ライフサイエンスコーパス: recombinant DNA

1 after transfection of CEMx174 cells with the recombinant DNA.

2 with purities approaching 90%, from a single recombinant DNA.

3 e-boost regimens with adjuvanted proteins or recombinant DNA.

4 In order to address these concerns, the Recombinant DNA Advisory Committee (RAC) held a symposiu

5 an UCLA Human Subject Protection Committee, Recombinant DNA Advisory Committee, and FDA-approved cli

6 macaques in the form of either purified VLP, recombinant DNA and canarypox (ALVAC) vectors engineered

7 easing database of natural enzyme diversity, recombinant DNA and fermentation technologies that allow

8 by ambitious scientists in the early days of recombinant DNA and follow the implementation of this te

9 ical advances, among them the development of recombinant DNA and its many applications, opened the wa

10 Recombinant DNA and modified vaccinia virus Ankara (rMVA

11 Recently, however, recombinant DNA and molecular phylogenetic techniques ha

12 emonstrate that prime-boost vaccination with recombinant DNA and MVA vectors can induce multifunction

13 For example, recombinant DNA and PCR are powerful tools used to isola

14 Using recombinant DNA and proteins in vitro, we demonstrate th

15 ical sciences spurred on by the discovery of recombinant DNA and the advent of automated DNA sequenci

16 ogies concurrent with the development of new recombinant DNA approaches have enabled the extension of

17 n of native chemical ligation technology and recombinant DNA approaches that are amenable to the in-c

18 Using recombinant DNA approaches, we demonstrated that the hem

19 al CPE deletion fragments was constructed by recombinant DNA approaches.

20 Purified recombinant DNAs are then injected into 1-2-cell zebrafi

21 echnologies such as combinatorial chemistry, recombinant DNA as well as computational multi-scale met

22 This recombinant DNA-B component, which contained the ToMoV o

23 infection in a chimpanzee HBV carrier using recombinant DNA-based immunization followed by a recombi

24 large intersubspecific cross, a panel of 53 recombinant DNAs between D15Mit29 and D15Mit2 has been a

25 Unlike the full-length ER, the recombinant DNA binding domain of ER did not discriminat

26 The recombinant DNA-binding antibody, called Fab-E box, bind

27 Full-length (67 kDa) ER or its 11 kDa recombinant DNA-binding domain (ER-DBD) is also suscepti

28 Recombinant DNA-binding protein B binds the selenocystei

29 Monoclonal antibodies and recombinant DNA biopharmaceuticals are derived from rela

30 matic and bacterial processes used to create recombinant DNA can introduce errors, sequence validatio

31 mbryonic stem (ES) cells, transfected with a recombinant DNA consisting of a fatty acid-binding prote

32 expression vectors were used to introduce a recombinant DNA construct containing enhanced green fluo

33 Our system uses a recombinant DNA construct in which the coding sequences

34 adenovirus vectors were used to introduce a recombinant DNA construct, containing the enhanced green

35 ering RNA (siRNA) duplexes within cells from recombinant DNA constructs, because this might allow lon

36 Recombinant DNA controls for each of these organisms wer

37 Using a recombinant DNA-derived alpha-neurotoxin (Naja mossambic

38 a day along with subcutaneous injections of recombinant DNA-derived insulin.

39 The assembly of large recombinant DNA encoding a whole biochemical pathway or

40 ve been reported previously after expressing recombinant DNAs, encoding CYP17 from various species, i

41 lating EMMPRIN expression and activity using recombinant DNA engineering and neutralizing antibodies.

42 should improve the efficiency of performing recombinant DNA experiments in Gram-positive bacteria.

43 pORT plasmid vectors designed to facilitate recombinant DNA exploitation.

44 his study with native, wild-type, and mutant recombinant DNA-expressed AChEs, each inhibited by repre

45 nsulin at the synthetic efficiency levels of recombinant DNA expression methods.

46 ation of the integrin alpha(IIb)beta(3) in a recombinant DNA expression model, and show that 14-3-3 i

47 es either in vitro or in vivo using standard recombinant DNA expression techniques.

48 An immunization protocol using injection of recombinant DNA followed by injection of recombinant mod

49 eterologous prime-boost vaccine regimen used recombinant DNA for priming and recombinant modified vac

50 uch greater versatility in the generation of recombinant DNA for the purposes of synthetic biology.

51 to the apoptotic changes in nuclei by using recombinant DNA fragmentation factor (DFF), a heterodime

52 ngineered plasmids contain sequences-such as recombinant DNA from all domains of life, wholly synthet

53 Production of recombinant DNA in bacterial cells is an essential techn

54 rom natural sources and by overexpression of recombinant DNA in Escherichia coli.

55 PNAS describing two methods for constructing recombinant DNAs in vitro.

56 g molecular mechanism for the integration of recombinant DNA into the genome of most eukaryotic syste

57 ing the introduction of a total of 1.1 Mb of recombinant DNA into their genomes.

58 Microinjection of recombinant DNA into zygotic pronuclei has been widely u

59 een included, which permits linearization of recombinant DNA irrespective of the characteristics of t

60 he presence of neither the GM strain nor its recombinant DNA is allowed for fermentation products pla

61 the goal of selecting, retrieving, and using recombinant DNA is exemplified by simple visual-based co

62 We also discuss the disposal of recombinant DNA, its persistence in the environment and

63 ell development within GCs, we constructed a recombinant DNA library enriched for cDNAs derived from

64 h the 5p maps of other groups using the same recombinant DNA library, a comprehensive map was constru

65 ey assumption-for a large randomly generated recombinant DNA library, there exists a staircase of DNA

66 Recombinant DNA ligase III was a substrate for calpain d

67 ponge'-based approaches, for which extensive recombinant DNA manipulation is required.

68 microbiota composition of ileum content (16S recombinant DNA massive sequencing), permeability (fecal

69 Epitope tagging is a recombinant DNA method by which a protein encoded by a c

70 ange of lengths of polyglutamine produced by recombinant DNA methodology by constructing a library of

71 SIT programs could be overcome by the use of recombinant DNA methods and molecular genetics.

72 ctionally active scIL5 was constructed using recombinant DNA methods by linking two IL5 monomers with

73 Recent developments have utilized recombinant DNA methods to prepare artificial protein hy

74 Recombinant DNA methods were used to create artificial p

75 Recombinant DNA methods were used to make the Streptococ

76 Specifically, recombinant DNA methods were used to prepare a protein t

77 or-intensive and time-consuming hybridoma or recombinant DNA methods.

78 y, misapprehensions and misinformation about recombinant DNA-modified (also known as 'genetically mod

79 For decades, in most regulatory frameworks, recombinant DNA-modified organisms have been the wrong f

80 mechanism is the lack of a system in which a recombinant DNA molecule undergoes cytokine-regulated cl

81 sing the same approach and that interspecies recombinant DNA molecules can produce a biologically fun

82 acts to assemble multiple DNA fragments into recombinant DNA molecules in a single in vitro recombina

83 ating plasmid, and introducing the resulting recombinant DNA molecules into bacteria.

84 ides a means for the in vivo construction of recombinant DNA molecules that may be problematic to ass

85 Efficient formation of recombinant DNA molecules was observed in ruvC+ recG+, r

86 ate the rapid and systematic construction of recombinant DNA molecules.

87 , that facilitates the rapid construction of recombinant DNA molecules.

88 keys were intramuscularly primed with either recombinant DNA (n = 4) or modified vaccinia virus Ankar

89 ays could reproducibly detect 10 copies of a recombinant DNA plasmid containing a partial region of t

90 We designed recombinant DNA plasmids encoding soluble multitrimers o

91 Recombinant DNA pol delta was also purified by immunoaff

92 Species-specific 16S recombinant DNA polymerase chain reaction assays targeti

93 Recombinant DNA polymerase delta efficiently replicated

94 mmunoprecipitation experiments revealed that recombinant DNA polymerase epsilon directly interacts wi

95 me into the public policy debates regarding recombinant DNA practices.

96 report unique mechanistic characteristics of recombinant DNA primase from Bacillus anthracis.

97 Here we examined recombinant DNA priming followed by subunit protein boos

98 ce in situ hybridization (FISH) using large, recombinant DNA probes consisting of contiguous genomic

99 nts a substantial advance in high-throughput recombinant DNA production that will save time, effort a

100 Plasma-derived and recombinant DNA products currently have good viral safet

101 Since 1987, dozens of purified recombinant DNA products derived from CCLs have been dev

102 ons, genetic recombination, formation of new recombinant DNA products, and the presence of both drug

103 ccine manufacturing, gene therapy, and other recombinant DNA products.

104 cobacterium bovis BCG (rBCG), electroporated recombinant DNA (rDNA) along with an interleukin-12 (IL-

105 owing biotic and economic threats, for which recombinant DNA (rDNA) technology can sometimes provide

106 f different origins is fundamental to modern recombinant DNA research.

107 , the extraordinarily exciting time when the recombinant DNA revolution hit yeast genetics.

108 CR cassettes facilitates the introduction of recombinant DNA sequences into the lambda-phage genome w

109 le and exportable forms of neuroligin-1 from recombinant DNA sources, by truncating the protein befor

110 c community, the 1975 Asilomar Conference on Recombinant DNA stands as a singular achievement.

111 to re-form a 3'-5' phosphodiester bond in a recombinant DNA strand.

112 t study with isogenic strains constructed by recombinant DNA strategies unambiguously documented that

113 analyzed in vitro using purified protein and recombinant DNA substrates that model the U3 and U5 ends

114 chain reaction (PCR) amplification of a 16S recombinant DNA target, and a mouse infectivity assay.

115 Here, we apply a recombinant DNA technique to investigate the role of dop

116 ted a single-headed dimer of L7/L12 by using recombinant DNA techniques and chemical cross-linking.

117 s study, AF17121 was fused to thioredoxin by recombinant DNA techniques and examined for IL5Ralpha in

118 biological control agents but development of recombinant DNA techniques has made it possible to signi

119 A number of new recombinant DNA techniques have been developed for genet

120 Recombinant DNA techniques have been used to add 14 amin

121 Development of recombinant DNA techniques in the 1970s and their applic

122 east for beta-keto ester reductions by using recombinant DNA techniques to alter the levels of three

123 part of my laboratory was using the then-new recombinant DNA techniques to clone and characterize man

124 + ... Cu1.5+ structure through spectroscopy, recombinant DNA techniques, and crystallography.

125 Using recombinant DNA techniques, we have identified the epito

126 Using recombinant DNA techniques, we prepared a fusion protein

127 m genomic DNA, and thus more quickly than by recombinant DNA techniques.

128 onsive control ELP in Escherichia coli using recombinant DNA techniques.

129 peptide, a fusion protein was produced using recombinant DNA techniques.

130 the family II CBD (E4-74) were made by using recombinant DNA techniques.

131 y of developing molecular computers based on recombinant DNA techniques.

132 tive pharmaceutical ingredients derived from recombinant DNA technologies and as a method to detect c

133 sis for improved approaches to gene-chip and recombinant DNA technologies and provide new insight int

134 Monoclonal antibody and recombinant DNA technologies have led to the development

135 Recombinant DNA technologies have opened the possibility

136 tome sequencing, mass spectrometry (MS), and recombinant DNA technologies were applied to characteriz

137 ng methods and as bispecific diabodies using recombinant DNA technologies.

138 loned, and its expression was analyzed using recombinant DNA technologies.

139 conjugation (GnRH-PAP conjugate) or through recombinant DNA technology (GnRH-PAP fusion).

140 The advent of recombinant DNA technology allowed the expression of EPO

141 Application of recombinant DNA technology and electrophysiology to the

142 nd alphaB-crystallins) have been prepared by recombinant DNA technology and shown to differ in the fo

143 for preventive allergy vaccination based on recombinant DNA technology and synthetic peptide chemist

144 ve helped to perpetuate 'The Big Lie' - that recombinant DNA technology applied to agriculture and fo

145 The framing of agricultural products of recombinant DNA technology as GMOs lacks biological cohe

146 iction endonucleases are used prevalently in recombinant DNA technology because they bind so stably t

147 ns (HCPs) in biopharmaceuticals derived from recombinant DNA technology can present potential safety

148 The advent of recombinant DNA technology changed this dramatically in

149 GMAP represents a recombinant DNA technology designed for widespread circu

150 designer low O(2) affinity Hbs generated by recombinant DNA technology for applications as Hb based

151 ority of chemical synthetic strategies used, recombinant DNA technology has allowed for the productio

152 At the same time, remarkable progress in recombinant DNA technology has enabled the development o

153 In the past 30 yr, introduction of recombinant DNA technology has facilitated the dissectio

154 Recombinant DNA technology has profoundly advanced virtu

155 The recent advances in recombinant DNA technology have begun to help to elucida

156 The contribution of recombinant DNA technology in defining the molecular pat

157 ch plakoglobin or parts thereof, produced by recombinant DNA technology in E. coli, are exposed to mo

158 With the advent of recombinant DNA technology in the 1970s, the idea of usi

159 Recombinant DNA technology is widely used for different

160 The advent of recombinant DNA technology made it possible to overcome

161 The emergence of recombinant DNA technology occurred via the appropriatio

162 proteins produced in different host cells by recombinant DNA technology often contain terminal GlcNAc

163 The production of proteins via recombinant DNA technology often requires the in vitro f

164 Recombinant DNA technology permits large-scale, low-cost

165 wild-type S. flexneri 2a by rational use of recombinant DNA technology that achieves a remarkable de

166 estriction enzymes (e.g. EcoRI) gave rise to recombinant DNA technology that has transformed molecula

167 In the present studies, we applied the recombinant DNA technology to prepare native, unmodified

168 successful drug spawned by the revolution in recombinant DNA technology".

169 Using recombinant DNA technology, 5C12 isotype variants (IgG1,

170 sessment of compounds, the implementation of recombinant DNA technology, and large-scale manufacture

171 Unlike recombinant DNA technology, embryonic stem cell research

172 Progress in recombinant DNA technology, genomics, and computational

173 locyte colony-stimulating factor produced by recombinant DNA technology, is frequently used to stimul

174 Building on recombinant DNA technology, leaps in synthesis, assembly

175 n drug development (using such techniques as recombinant DNA technology, site-directed mutagenesis, p

176 Through recombinant DNA technology, the alphavirus RNA replicati

177 Using recombinant DNA technology, the present study provides t

178 Before the application of recombinant DNA technology, these two alpha-crystallin s

179 Through recombinant DNA technology, tPA was cloned and modified

180 ining a complete recombinant KSHV genome and recombinant DNA technology, we inserted stop codons into

181 Recombinant DNA technology, which is based on the assemb

182 ated since their successful production using recombinant DNA technology.

183 It is a live vaccine developed using recombinant DNA technology.

184 biological research is highly dependent upon recombinant DNA technology.

185 to prevent these complications by the use of recombinant DNA technology.

186 inhibitor, turkey ovomucoid third domain, by recombinant DNA technology.

187 ecombine genes from different pathways using recombinant DNA technology.

188 must be produced in heterologous hosts using recombinant DNA technology.

189 A into the microbial cells is fundamental in recombinant DNA technology.

190 ) were fused to the Fc portion of IgG1 using recombinant DNA technology.

191 h no affinity receptor is available by using recombinant DNA technology.

192 red from mammalian cell cultures by means of recombinant DNA technology.

193 lagellin protein of S. typhi was prepared by recombinant DNA technology.

194 End ligase activity may have applications in recombinant DNA technology.

195 ns, but only a few LAB have been modified by recombinant-DNA technology because of consumer resistanc

196 ch for the rapid and efficient generation of recombinant DNA that can be used for parallel processing

197 y laboratory developed a method for creating recombinant DNAs that led us and others, over the next t

198 netically engineered functions and confining recombinant DNA to intended hosts are necessary to cope

199 The EcoRI endonuclease is an important recombinant DNA tool and a paradigm of sequence-specific

200 owth rate, culture conditions, and available recombinant DNA tools.

201 ted from a 55-year-old male with OAC without recombinant-DNA transformation.

202 mors could markedly affect the expression of recombinant DNA under control of both inducible and cons

203 he cell-mediated immune profile induced by a recombinant DNA vaccine was assessed in the simian/HIV (

204 useful for future rational designs of other recombinant DNA vaccines targeting tissue differentiatio

205 In this study, we used a recombinant DNA virus expressing different forms of a mo

206 rpesvirus type 2 (GHV-2) genomes, generating recombinant DNA viruses that now circulate in wild birds

207 llows efficient and reproducible assembly of recombinant DNA with as many as 5 and 10 fragments simul

208 io in the 1960s and 1970s, later followed by recombinant DNA work in the 1990s, which led to a reviva