ライフサイエンスコーパス: recombinant antigen

1 tion with common components of gTSSA-II/V/VI recombinant antigen.

2 orious solubilization procedures to generate recombinant antigen.

3 acids) was then designed and expressed as a recombinant antigen.

4 fic antibodies based on a WNV preM/E protein recombinant antigen.

5 (88.9%) contained antibodies to one or more recombinant antigens.

6 24 (80%) contained antibodies to one or more recombinant antigens.

7 41-G antigen and to one or more of the other recombinant antigens.

8 tilising 24 MPXV and 3 Vaccinia virus (VACV) recombinant antigens.

9 ts potency as a vaccine against poxvirus and recombinant antigens.

10 antage and enhance immunization of expressed recombinant antigens.

11 cted positively by an ELISA with one or more recombinant antigens.

12 Subcutaneous vaccination with recombinant antigen 2/PRA (rAg2/PRA) protected BALB/c mi

13 E cross-reactivity on molecular level, seven recombinant antigens 5 of the most important Vespoidea g

14 th venom extracts than in sIgE analyses with recombinant antigens 5.

15 No cross-reactivity with recombinant antigen 5a was found with sera from patients

16 Recombinant antigens 5a and 12a detected parasite-specif

17 sIgE against recombinant antigen 5s sensitization to be detected in 5

18 infection-primed lines were challenged with recombinant antigen 85 (Ag85) proteins.

19 ly higher CD8(+)-T-cell response against the recombinant antigen after challenge with recombinant L.

20 Five recombinant antigens (Ags; 85A, 85B, 85C, superoxide dis

21 binations of the previously described 27-kDa recombinant antigen and the 87-kDa heat shock protein we

22 The cartridge incorporates a microarray of recombinant antigens and antibody controls in a fluidic

23 81 women were assayed for antibodies against recombinant antigens and for IgG and opsonising antibodi

24 id apoptosis, leading to faster clearance of recombinant antigens and potentially blunting a greater

25 s, levels of antibodies in pregnant women to recombinant antigens and to intact IEs but not of opsoni

26 of multigravidae are not depleted on VAR2CSA recombinant antigens, and hence development of VAR2CSA v

27 munosorbent assay (ELISA), immunoblotting of recombinant antigens, and immunoprecipitation of 35S-met

28 Mycobacteria expressing recombinant antigens are already being developed as vacc

29 These results suggest that none of the four recombinant antigens are immunodominant, and that the 10

30 In phase 1, recombinant antigens are screened for reactivity to the

31 Highly pure recombinant antigens are typically very poorly immunogen

32 of a cocktail of three to four synthetic or recombinant antigens, based on the diagnostic bands of t

33 we have evaluated the performance of the new recombinant antigen-based Abbott AxSYM CMV IgM assay and

34 Recombinant antigen-based assays significantly increase

35 tudinally by quantitative PCR and by the new recombinant antigen-based AxSYM immunoassay for IgM to H

36 nt assay (ELISA) also tested positive by the recombinant antigen-based immunoassay (VacRIA).

37 nti-ZIKV immunoglobulin G antibodies using a recombinant antigen-based SGERPAxMap microsphere immunoa

38 guide the design and engineering of improved recombinant antigen-based vaccines.

39 lin M (IgM) by use of a monoclonal antibody, recombinant-antigen-based IgM capture enzyme immunoassay

40 rage may affect development of antibodies to recombinant antigens, but levels of opsonizing IgG remai

41 dy has identified, for the first time, three recombinant antigens capable of inducing protective immu

42 oth the secreted and nonsecreted form of the recombinant antigen compared to the response of naive mi

43 In particular, by using a combination of recombinant antigens, competitive inhibition assays, and

44 Recombinant antigens comprising truncated capsid protein

45 ), a licensed Nm vaccine containing OMVs and recombinant antigens, comprising a single arm, open labe

46 es to native antigen 85, indicating that the recombinant antigen contained T-cell and B-cell epitopes

47 While antibodies to recombinant antigens declined between enrolment and deli

48 etween enrolment and delivery, antibodies to recombinant antigens decreased, whereas antibodies to IE

49 dual or combinations of purified leishmanial recombinant antigens delivered as plasmid DNA constructs

50 In rabbit immunizations, a recombinant antigen derived from the basal virus showed

51 cteria could serve as a vaccine platform for recombinant antigens derived from other pathogens, aller

52 A panel of seven recombinant antigens, derived from Ehrlichia phagocytoph

53 The recombinant antigen elicited proliferation and gamma int

54 A cocktail of the recombinant antigens ESAT-6, MPB83, and MPB64 failed to

55 beta-glucosidases of other organisms, but a recombinant antigen expressed in a prokaryotic system sh

56 results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium

57 We describe a recombinant antigen for use in serologic tests for antib

58 using a model antigen and F1-V, a candidate recombinant antigen for Yersinia pestis, the causative a

59 These data identify new recombinant antigens for evaluation in vaccines and diag

60 with 100% sensitivity and specificity using recombinant antigens for the SARS-CoV-2 spike S1 protein

61 To address this unmet need, we evaluated recombinant antigens for their ability to detect serum a

62 eins that should be considered for design of recombinant antigens for vaccine trials and that implica

63 ella enterica serovar Typhimurium expressing recombinant antigens from other pathogens elicits primar

64 heavy and light chains assembled to bind the recombinant antigen GA733-2E and specifically bound to h

65 This recombinant antigen has great potential to become the an

66 djuvants in enhancing the immune response to recombinant antigens has led many researchers to re-focu

67 ht influence the chosen strategy to localize recombinant antigen in RASVs.

68 ycobacterium tuberculosis was expressed as a recombinant antigen in the nonpathogenic mycobacterial h

69 and appropriate subcellular location of the recombinant antigen in the Salmonella vaccine strain may

70 idence is presented for immune protection by recombinant antigens in a mouse model of C. ruminantium

71 ave evaluated the diagnostic utility of five recombinant antigens in enzyme-linked immunosorbent assa

72 ities against the gonococcal homologs of the recombinant antigens in the vaccine peaked at 10 but had

73 Purified preparations of recombinant antigens included outer surface protein A (O

74 noblotting were performed by using purified, recombinant antigens including F1, V antigen, YpkA, YopH

75 This recombinant antigen induced strong humoral and cellular

76 erologous IN boosting with NE/IVT adjuvanted recombinant antigen induces strong mucosal and systemic

77 Since production of recombinant antigen is faster and less expensive than pr

78 A recombinant antigen (Ll-SXP-1), preferentially recognize

79 n that a cocktail containing two leishmanial recombinant antigens (LmSTI1 and TSA) and interleukin-12

80 uman B cells and antibodies, using viral and recombinant antigens, mainly led to the isolation of dom

81 The assay was validated against purified recombinant antigens, monospecies malaria infections, an

82 hich contains the MeNZB OMV component plus 3 recombinant antigens (Neisseria adhesin A, factor H bind

83 us), a reservoir host species, with either a recombinant antigen of the pathogen, outer surface prote

84 to ehrlichiae revealed IgM antibodies to all recombinant antigens of B. burgdorferi except OspB and I

85 re immunized with the OMV component or the 3 recombinant antigens of Bexsero, and Western blots and e

86 nosorbent assays (ELISAs) with whole-cell or recombinant antigens of Borrelia burgdorferi sensu stric

87 immunosorbent assays (ELISAs) with purified recombinant antigens of Borrelia burgdorferi sensu stric

88 Recombinant antigens of Cryptosporidium parvum, Cp900 an

89 Luminex microspheres were coupled to recombinant antigens of genogroup I (GI) and II (GII) no

90 In contrast to earlier studies based on recombinant antigens of M. tuberculosis which suggested

91 Recombinant antigens of outer surface proteins (Osps) Os

92 The recombinant antigens of this library were used to stimul

93 lyzed for immunoglobulin (Ig) G responses to recombinant antigens of three noroviruses and Cryptospor

94 igens on persistently HIV-infected cells and recombinant antigens on Env-transfected cells.

95 be used in a QCM assay, in lieu of native or recombinant antigens or capture antibodies, to rapidly d

96 is system provides a method by which several recombinant antigens or reporter constructs can be seque

97 Five recombinant antigens, Ov7, Ov64, OvB8, Ov9M, and Ov73k,

98 The second recombinant antigen, pAg-1C, contained the remaining C-t

99 The first recombinant antigen, pAg-1N, contained the N-terminal 33

100 The availability of recombinant antigen [particularly thyroid peroxidase and

101 ely high degrees of specificity, ELISAs with recombinant antigens, particularly OspC and p41-G, can h

102 nd the IFA titers when greater than 50 ng of recombinant antigen per dot was used.

103 The combination of rK26 and rK39 recombinant antigen prepared from Iranian strain of Leis

104 were analyzed in parallel using immobilized recombinant antigens (rAgs) of HEV genotypes 1 and 3 and

105 g two recombinant outer membrane proteins as recombinant antigens (RCA) and a whole-cell inactivated

106 tigens affinity purified with MAb 4F11 and a recombinant antigen reactive with MAb 4F11.

107 (87%) of 15 serum samples had antibodies to recombinant antigens; reactivity to p22, p39, p41-G, Osp

108 ied and sequenced a subset of genes encoding recombinant antigens recognized by antibody and peripher

109 Nanobodies are the recombinant antigen-recognizing domains of the minimalis

110 n the present study, a series of overlapping recombinant antigens representing the polymorphic outer

111 In addition to two MSP recombinant antigens (rHGE-1 and -3) and a fusion protei

112 The final two recombinant antigens (rHGE-9 and -17) represent overlapp

113 These recombinant antigens should be useful in diagnostic and

114 ctivities to rK39 were tested with the novel recombinant antigens, some of the sera showed stronger a

115 mice were immunized with the five individual recombinant antigens, statistically significant reductio

116 -IgG4 PoC-ICT is superior amongst the single recombinant antigen tests for diagnosing fluke infection

117 cause it is thus far the only E. chaffeensis recombinant antigen that has been shown to work in an EL

118 ouis encephalitis virus (SLEV) noninfectious recombinant antigen that is a safe and easily produced a

119 NHBA is the only Bexsero recombinant antigen that is conserved and surfaced expos

120 was studied previously in L. aethiopica as a recombinant antigen that reacts with human antibodies.

121 velop a vaccine against this infection using recombinant antigens that are expressed in the early lar

122 Only recombinant antigens that contain a nine-amino acid (AA)

123 full-length protein and was not induced with recombinant antigens that contained only the C-terminal

124 frequently reacted positively to one or more recombinant antigens, the inclusion of OspF and p41-G an

125 sponses by facilitating adequate exposure of recombinant antigen to antigen-presenting cells for proc

126 be a powerful platform that can both deliver recombinant antigen to DCs for presentation and provide

127 capacity of four Mycobacterium tuberculosis recombinant antigens to elicit proliferation and cytokin

128 urium has been used for targeted delivery of recombinant antigens to gut- and nose-associated lymphoi

129 nt vaccines to serve as factories to produce recombinant antigens to induce the desired protective im

130 urium has been used for targeted delivery of recombinant antigens to the gut-associated lymphoid tiss

131 mL (95% CI of 0.53 to 0.77 ng/mL) ng/mL with recombinant antigen using an optical reader with sensiti

132 A recombinant antigen vaccine against Schistosoma mansoni

133 ions are described and initial success using recombinant antigen vaccines in these models is reviewed

134 Using newly generated recombinant antigen variant-expressing chronic lymphocyt

135 The recombinant antigen was reactive in IgM immunoblots usin

136 ermine whether the protective epitope of the recombinant antigen was sensitive to denaturation, recom

137 The gene encoding the recombinant antigen was sequenced, and database analysis

138 This recombinant antigen was subsequently used to design an a

139 n was expressed in Escherichia coli, and the recombinant antigen was used in a western line-blot.

140 gh the results of class-specific ELISAs with recombinant antigens were comparable to those recorded f

141 Purified recombinant antigens were employed to detect antibodies

142 The IBMP 8.1 and rLci1A/rLci2B recombinant antigens were immobilized over the surface o

143 mmunosorbent assay and western blotting, all recombinant antigens were shown to be antigenic.

144 The proliferative responses to the four recombinant antigens were similar in all patient groups,

145 e-based vaccine platforms and formulation of recombinant antigens with potent adjuvants.

146 om the CDC, comparing ELISAs using these two recombinant antigens with the 2-tier test method.

147 None of the recombinant antigens yielded false-positive results.