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1 ression and that they are also intrinsically recombinogenic.
2 , with the former being 10 to 100 times more recombinogenic.
3 5'-nuclease, which permits the generation of recombinogenic 3'-overhanging, single-stranded DNA (ssDN
5 s of a repeat motif highly homologous to the recombinogenic 76-bp repeat sequences present upstream o
10 ce reporter transgenes, we demonstrate a new recombinogenic activity of AID leading to intra- and int
12 gene-containing ecotropic virus demonstrated recombinogenic activity with endogenous FeLV sequences i
13 e that combining RNP delivery with naturally recombinogenic adeno-associated virus (AAV) donor vector
16 single-stranded gene insertion cassettes are recombinogenic and that these cassettes preferentially t
19 ls how genomic plasticity within lineages of recombinogenic bacteria can permit adaptation to clinica
25 s at an early step of recombination in a pro-recombinogenic complex with Rlp1 and Rdl1, two RecA-like
26 Int protomers, within a multiprotein 400-kDa recombinogenic complex, is thought to bind and, with the
30 rm-type sites in integrative versus excisive recombinogenic complexes reflects the regulation of reco
34 leost fish IgL each contain only two to four recombinogenic components (one to three V, one J) and ex
38 such DNA:RNA hybrids constitute a source of recombinogenic DNA damage taking advantage of Rad51-inde
43 idence that marker exchange is stimulated by recombinogenic DNA lesions formed as intermediates in th
44 ry of replicative DNA polymerases results in recombinogenic DNA lesions, presumably double-strand DNA
46 However, it has also been suggested that recombinogenic DNA:RNA hybrids could be facilitated by t
48 ication efficiencies (>10%) by introducing a recombinogenic double-strand break into the targeted gen
51 iety of cells and cell types by delivering a recombinogenic DSB to the targeted chromosomal locus, us
53 lines will enhance the utility of the hyper-recombinogenic DT40 cell line as a system for the geneti
54 genetic study was undertaken using the hyper-recombinogenic DT40 chicken cell line and a series of mu
55 e from these findings that the mutagenic and recombinogenic effects of msDNAs are due to titrating ou
57 targeting vector was constructed with small recombinogenic ends (500 bp) derived from flanking seque
58 ectively cloned by recombination between the recombinogenic ends in the targeting vector and homologo
59 linear DNA containing YAC-specific, unique, recombinogenic ends, thereby ensuring co-integration of
61 te full-length 3'-UTR reporter constructs by recombinogenic engineering (recombineering) in vivo clon
64 alters the chromosomal architecture in that recombinogenic factors accumulate, fostering large-scale
65 t Rad9 promotes stable annealing between the recombinogenic filament and the donor template in yeast,
66 ombinogenic form of the RecBCD enzyme into a recombinogenic form by causing two distinct enzymatic ch
68 Smc5/6 complex can counteract/modulate a pro-recombinogenic function of Mph1 or facilitate the resolu
71 s RecBCD from a destructive exonuclease to a recombinogenic helicase, we mutated the nuclease catalyt
73 metabolic burden imposed by the plasmid in a recombinogenic host, rather than to ensure plasmid stabi
75 tability yet revealed that this locus may be recombinogenic in a primarily clonal population structur
77 ich causes DNA strand breakage and is highly recombinogenic in some model organisms, was tested for i
78 he repeats at the replication fork creates a recombinogenic intermediate that can be differentially p
79 tioning and spatial proximity of potentially recombinogenic intrachromosomal loci.Oncogene advance on
80 he potential of a donor sequence to act as a recombinogenic, invasive end is determined by the stabil
81 sulted in the presence of large and probably recombinogenic LCRs across the region, the creation of t
82 mutation, rfa1-D228Y, causes an increase in recombinogenic lesions as well as the activation of a RA
83 loss of heterozygosity events stemming from recombinogenic lesions on the ribonucleotide-containing
87 ains indicates a persistent albeit decreased recombinogenic lifestyle near the emergence of the MTBC.
88 nsights into the genetic structure of highly recombinogenic loci responsible for combinatorial geneti
89 ic region encoding these proteins revealed a recombinogenic locus with PfRh2a and PfRh2b in a head-to
91 ne, suggesting involvement of a common novel recombinogenic mechanism that might also contribute to t
92 PCR to reconstruct missing elements from the recombinogenic middle region of pspB, SP85 was shown to
93 usion events into a distinct group of highly recombinogenic, multireplicon, self-transmissible plasmi
94 ght to have originated in East Africa from a recombinogenic Mycobacterium canettii-like ancestral poo
95 his method exploits the highly efficient and recombinogenic nature of DNA uptake during natural trans
102 eral previous studies have indicated a hyper-recombinogenic phenotype in the absence of active PARP1
108 by K63-linked polyubiquitylation triggers a recombinogenic process involving template switching.
110 lity in strand transfer have illuminated the recombinogenic properties of type IB topoisomerases and
111 he BRCA2 C terminus was thought to stabilize recombinogenic RAD51 after the assembly of ATP-extended
113 Although critically short telomeres are very recombinogenic, recombination among telomeres that have
114 plasmid recombination events in this highly recombinogenic region, even in the absence of viral enzy
115 nation hotspot is located within the 'highly recombinogenic' region of the full-length CaMV RNA that
116 in the large internal repeats, as well as to recombinogenic regions of cellular DNA, such as variable
117 netically dissect and molecularly manipulate recombinogenic regions to test their roles in regulating
119 rent Alu elements, combined with a potential recombinogenic role of retrotransposon target-site dupli
122 he co-location of these genes on a small non-recombinogenic segment simplifies their deployment as a
124 (TRBP) was found to recognize several G-rich recombinogenic sequences in the EBV genome and in cellul
128 ent processing of broken DNA ends to produce recombinogenic single-stranded DNA competent for HR.
130 ture is the narrow 1.5-2.5-kb width of these recombinogenic sites, these analyses revealed that hot s
131 lly evolving the naturally transformable and recombinogenic species Acinetobacter baylyi with a cockt
132 he genetic macrovariation within a low-level recombinogenic species would accurately be characterized
134 these changes is the production of a highly recombinogenic structure known as the presynaptic filame
136 ase, gammadelta resolvase, form a simplified recombinogenic synaptic complex containing a tetramer of
140 m that murine leukemia virus replicative and recombinogenic template switches differ in homology requ
143 tep process, few seek to exploit the natural recombinogenic tendencies and exponential amplification
144 ipeline showed generally higher abundance in recombinogenic than in nonrecombinogenic regions of the
145 f the proposal that broken DNA ends are more recombinogenic than internal sequences, we have investig
146 tors that make wild-type female meiosis less recombinogenic than male wild-type meiosis do not apply
148 aking HIV-1 up to an order of magnitude more recombinogenic than recognized previously and demonstrat
150 te homology facilitates both replicative and recombinogenic transfers, but homology-independent deter
151 ype cells that are normally removed in a non-recombinogenic way, possibly by Rqh1 catalysing their re