ライフサイエンスコーパス: reconstitute

1 ontaining a sessile and a pendant channel is reconstituted.

2 We present here the structure of a reconstituted 13-subunit Ctf19c determined by cryo-elect

3 e marrow-liver-thymus) humanized mice, which reconstitute a functional human immune system, develop p

4 In this work we reconstitute a fungal bioluminescence pathway (FBP) in p

5 Here, we reconstitute a parS-dependent ParB spreading event using

6 Here, we reconstituted a complete chemotransduction signaling com

7 This report is the first example of reconstituting a trans-acyltransferase assembly line PKS

8 Here, we reconstitute accelerated and selective deadenylation of

9 mics in a budding yeast nuclear extract that reconstitutes activator-dependent transcription in vitro

10 We have reconstituted active C/D RNPs with recombinant proteins

11 For the dimerization, we reconstitute acto-myosin connection of a tailless E-cadh

12 Here, we reconstitute AID-catalyzed deamination during Pol II tra

13 confirms the mechanical contribution of the reconstituted AJs.

14 of long-term expansion in vitro, and able to reconstitute an anatomic phenocopy of the native thymus,

15 We reconstituted an active human histone pre-mRNA processin

16 tain enteric neuronal progenitors capable of reconstituting an enteric nervous system when transplant

17 By reconstituting an OmpF porin in an artificial lipid bila

18 Here we reconstitute and dissect the substrate specificity under

19 Preservative-free powders were reconstituted and applied to coat sliced cakes, a bakery

20 Using both reconstituted and ciliary polycystin channels, we furthe

21 We therefore reconstituted and imaged the early stages of HIV-1 repli

22 on of proteins in direct contact with DNA in reconstituted and native chromatin after cross-linking b

23 cal systems have been identified that can be reconstituted and studied in vitro under defined conditi

24 evolution of material properties, can all be reconstituted and understood via a minimal macromolecula

25 to diverse proximity triggers and capable of reconstituting and locally activating the acetyltransfer

26 ated that the used type of water (distilled, reconstituted, and rainwater) does not influence the out

27 some positioning sequences are often used to reconstitute arrays of nucleosomes in vitro.

28 Variants of these bNAbs reconstituted as IgA demonstrated broadly neutralizing a

29 Here we reconstitute assembly of mammalian, non-muscle actin fil

30 We show that this preparation of SUV-reconstituted ATP synthase monomers, when fused into gia

31 rapy with gamma-retroviral vectors failed to reconstitute B-cell and NK-cell immunity and was complic

32 transcription complexes and R-loops using a reconstituted bacterial DNA replication system.

33 rently with network formation on Matrigel, a reconstituted basement membrane matrix regularly used to

34 Compared with detergent-reconstituted beta(2)AR, the beta(2)AR in HDL particles

35 Whereas cell-free reconstituted biopolymer networks typically soften under

36 ) to track the contribution of HSC clones to reconstituted blood.

37 ally degradable interpenetrating networks of reconstituted BM matrix and alginate, which presented a

38 imized a fusion/electroformation approach to reconstitute bo (3) oxidase in giant unilamellar vesicle

39 ied Xenopus laevis proteins we biochemically reconstitute branching microtubule nucleation, which is

40 Our work therefore conclusively reconstitutes branching MT nucleation.

41 Using the reconstituted budding yeast DNA replication system, we f

42 Here, we have reconstituted budding yeast Hsf1-Hsp70 activation comple

43 Using reconstituted budding yeast replisomes, we show that mut

44 tern" with reaction components being rapidly reconstituted by 10 muL sample addition, enabling detect

45 . mutans biofilm extracellular matrices, are reconstituted by co-incubation of monomers and amyloid f

46 osine and adenine base editors that are then reconstituted by trans-splicing inteins.

47 ure has been determined and the virus can be reconstituted by transgenesis of the host.

48 Using genetically-reconstituted Caco-2 cysts as proxy for polarized epithe

49 We reconstituted cccDNA formation with purified human homol

50 the lack of a biochemical system that fully reconstitutes cccDNA formation.

51 on signaling events and was even observed in reconstituted cell-free liposomes.

52 Infection of the reconstituted cells with HSV-1 revealed that both the cG

53 We further quantitatively characterize the reconstituted chromatin folding structures by identifyin

54 ablish nucleosome-depleted regions (NDRs) in reconstituted chromatin, and was implicated in removing

55 c Bmal1-null mice, we generated animals with reconstituted circadian expression of BMAL1 exclusively

56 We reconstitute cohesin as tri- or tetrameric assemblies an

57 rheology with exponents that match those of reconstituted collagen and actomyosin networks prestress

58 Here, we combine shear rheology of reconstituted collagen networks with computer simulation

59 Here, by reconstituting components of human UPR, ER stress and Bi

60 both in vivo and in an in vitro system that reconstitutes DDR events on nucleosomes.

61 al proteasome complex ClpXP degrades MinD in reconstituted degradation reactions in vitro and in vivo

62 ral to T cell exhaustion, thymic cellularity reconstituted despite ongoing viral replication, with a

63 We reconstituted detergent-purified mitochondrial ATP synth

64 Additional analyses revealed that ART reconstituted different quantities of CD4(+) T lymphocyt

65 -C cells indicated that Dist-Luminal-C cells reconstituted distal prostate luminal lineages through s

66 we combine FRAP experiments on both in vitro reconstituted droplets and intracellular condensates wit

67 Here, we co-reconstituted ECF transporters for folate (ECF-FolT2) an

68 istinguish between the two C/D motifs in the reconstituted enzyme, suggesting that the assembly speci

69 sing the conventional 'on-bead' approach, we reconstituted Escherichia coli proteins MsbA and MscS an

70 and then used to characterize fractions and reconstituted extracts of field-collected OSPW.

71 ty of individual IOCs, acidic fractions, and reconstituted extracts of OSPW was observed.

72 ism in regulating multicellular processes in reconstituted fibrin gels.

73 without temperature restrictions and easily reconstituted for preparation of eyedrops for standard c

74 to the generation of mouse chimeras with ESC-reconstituted forebrain regions that can be directly ana

75 omain architecture of protein-free membranes reconstituted from IM and OM lipids in vitro from M. sme

76 The only exception is a gyrase reconstituted from mycobacterial GyrA and B. subtilis Gy

77 rculosis gyrases and of heterologous enzymes reconstituted from subunits of two different species.

78 Here we reconstitute fuscanodin biosynthesis in vitro with purif

79 Reconstituted fusion involving a lipid-mixing assay indi

80 We have reconstituted fusion with pure components from yeast vac

81 Experiments in reconstituted gamma-KO cells, whose gamma subunits are l

82 nd on the biological response of an in vitro reconstituted gingival epithelium tissue.

83 Here, we show that bioprinted reconstituted glioblastoma tumours consisting of patient

84 of transport dynamics of unlabeled membrane-reconstituted Glt(Ph), a prokaryotic EAAT homologue, wit

85 A-associated VPS34CII kinase activation in a reconstituted GTP-Rab5A-VPS34CII-PI3P-PX signaling pathw

86 le FRET assay to probe the folding status of reconstituted hairpins in lipid bilayers, we found that

87 PON1 activation/stabilization compared with reconstituted HDL (WT apoA-I, 1.92 +/- 0.04; 5-OHTrp(72)

88 Here, reconstituted HDL formulations are oriented on glass sub

89 Using a panel of reporter assays in reconstituted HEK293T/17 cells, we found that GPR139 fun

90 ry response to beta-adrenergic agonists when reconstituted heterologously with beta(2B) and Rad or tr

91 use heterologous expression to functionally reconstitute human uniporter machinery both in wild-type

92 n microscopy to determine the structure of a reconstituted human 48S The structure reveals insights i

93 determined the cryo-EM structure of nanodisc-reconstituted human ABCB4 trapped in an ATP-bound state

94 1 x 10(7) of human spleen mononuclear cells reconstituted human CD45(+) cells that were predominantl

95 Using single-molecule imaging of reconstituted human DNA repair factors, we identify phos

96 3 (-/-) mouse B cells and decreased in TRAF3-reconstituted human multiple myeloma cells.

97 o address specific mechanistic questions, we reconstituted human RNAPII promoter-proximal pausing in

98 2D in vitro tumor immunotherapy models have reconstituted immortalized cancer cell lines with immune

99 hing between thymus donor and recipient, the reconstituted immune system displays tolerance toward th

100 ed immunodeficiency (SCID-X1) often fails to reconstitute immunity associated with T cells, B cells,

101 oting IL-4Ralpha mutation; and hu cord blood-reconstituted immunodeficient, hu cytokine-secreting, mi

102 tsZ complex enhances the dynamics of Z rings reconstituted in a heterologous system.

103 ved from experiments with purified receptors reconstituted in detergent micelles.

104 The RCD-1 incompatibility system was reconstituted in human 293T cells, where coexpression of

105 M2 muscarinic or beta2-adrenergic receptors reconstituted in lipid nanodiscs activate Src by reducin

106 in complex with M2 muscarinic receptor (M2R) reconstituted in lipid nanodiscs.

107 elegans cyclic GMP-activated channel TAX-4, reconstituted in lipid nanodiscs.

108 s LRRC8A in complex with the inhibitor DCPIB reconstituted in lipid nanodiscs.

109 opy structure of substrate-bound human ABCB1 reconstituted in lipidic nanodiscs, revealing a single m

110 rom Torpedo electric tissue and functionally reconstituted in lipids optimal for cryo-electron micros

111 The pKa of D97 was compared between PR reconstituted in liposomes with different net headgroup

112 tivity), which requires powder samples to be reconstituted in liquid.

113 tent experimental observations is that, when reconstituted in membranes formed by zwitterionic phosph

114 crete equilibrium conformational states when reconstituted in membranes.

115 (DEER) between pairs of spin labels in MdfA, reconstituted in nanodiscs, with cysteine cross-linking

116 For PR reconstituted in net positively charged compared to net

117 ifference in the pKa of D97 observed from PR reconstituted in oppositely charged liposome environment

118 The membrane proteins are reconstituted in peptide discs, deposited on a solid sur

119 the effects of temperature on VDAC channels reconstituted in planar lipid membranes at the single- a

120 Membrane proteins can be reconstituted in polymer-encased nanodiscs for studies u

121 demonstrate that human DHHC20 is active when reconstituted in POPC nanodiscs.

122 onstrate that semi-recombinant holo U7 snRNP reconstituted in this manner has the same composition an

123 normal functioning of the transporter, when reconstituted in vesicles of defined lipid composition.

124 Here, using a DNA replication system reconstituted in vitro in tandem with a LexA cleavage as

125 ionic-strength buffers, thereby serving as a reconstituted in vitro model for muscle thick filaments.

126 nd accurately cleaves histone pre-mRNAs in a reconstituted in vitro processing reaction.

127 chia coli and paired that model with a fully reconstituted in vitro system to examine the capabilitie

128 Reconstituted in vitro systems have largely contributed

129 Here, we use a reconstituted in vitro transcription system with purifie

130 , PORCN-mediated Wnt lipidation has not been reconstituted in vitro with purified enzyme.

131 The motor and filament system can be reconstituted in vitro with the surface-adhered motors t

132 Kinetochore-fibers cannot be reconstituted in vitro, and exerting controlled forces i

133 OMP assembly has been reconstituted in vitro, but assembly reactions have invo

134 es, as well as the structure of M1 oligomers reconstituted in vitro.

135 These cells resuscitate rapidly to reconstitute infections once the stress is removed and n

136 By reconstituting initial biosynthetic steps in a heterolog

137 an agonist-bound activated DRD2-G(i) complex reconstituted into a phospholipid membrane.

138 examine the structural details of KirBac1.1 reconstituted into both POPC and an activating lipid mix

139 ures of the full-length GlyR protein complex reconstituted into lipid nanodiscs that are captured in

140 lectron microscopy structures of human TRPV3 reconstituted into lipid nanodiscs, representing distinc

141 n detergent-solubilized SthK and in channels reconstituted into lipid nanodiscs.

142 Monomers of mitochondrial ATP synthase reconstituted into liposomes do not bend membrane visibl

143 with green fluorescent protein that had been reconstituted into nanodiscs or proteoliposomes.

144 monitoring the two sides of the transporter reconstituted into nanodiscs reveal large-amplitude move

145 We report Cryo-EM structures of Glt(Ph) reconstituted into nanodiscs, including those structural

146 rial voltage-dependent anion channel (VDAC), reconstituted into planar bilayers of a plant-derived li

147 nalysis of mSlc35a3 and its genetic variants reconstituted into proteoliposomes disclosed the followi

148 ingle recombinant cellulose synthase isoform reconstituted into proteoliposomes opens new doors to fu

149 The t-SNARE acceptor complex DeltaN49 was reconstituted into PSMs containing 2 mol % 1,2-dipalmito

150 rifugation to be dismantled and subsequently reconstituted into vesicles.

151 Here we show that membrane-reconstituted IrtAB is sufficient to import mycobactins,

152 , we characterized the domains of MtBzaC and reconstituted its methyltransferase activity with the pr

153 d most of the quantified compounds, with the reconstituted juice having good nutritional quality.

154 Here we have biochemically reconstituted key elements of this pro-crossover pathway

155 The reconstituted kinetochores are capable of self-assemblin

156 Using reconstituted Las1 HEPN-HEPN' chimeras, we defined the m

157 Finally, we use purified proteins to reconstitute LC3- and JMY-dependent actin network format

158 We show that membrane-reconstituted LHCII contains selective sites that underg

159 microscopy (cryo-EM) structures of nanodisc-reconstituted ligand-free TRPA1 and TRPA1 in complex wit

160 deuterium-labeled lipoprotein substrate with reconstituted Lit to investigate intramolecular acyl cha

161 ating that our workflow is not restricted to reconstituted materials.

162 ver a specific requirement of CL for in vivo reconstituted MCU stability and activity.

163 aseline mechanosensitivity, is sufficient to reconstitute mechanically activated currents.

164 ndicates that measurements on OM proteins in reconstituted membrane systems may not reflect the nativ

165 ace, we developed an in vitro assay based on reconstituted membrane-coated target particles to which

166 Senescent RBCs with reconstituted membranes were phagocytosed in significant

167 Mid-infrared analysis of reconstituted milk is proposed as a feasible solution fo

168 of patchy particles has made it possible to reconstitute molecules and macromolecules of simple geom

169 Using reconstituted mononucleosomes containing a site-specific

170 Importantly, reconstituting myosin activity is sufficient to restore

171 ferentiate in the damaged environment of the reconstituting niche.

172 ronomic exploitation, leading to a desire to reconstitute novel oil biosynthesis in crop plants.

173 Recent studies with reconstituted nucleosomes in vitro and chromatin binding

174 ork describes a novel, streamlined method to reconstitute OMP assembly in vitro.

175 Nucleosomes reconstituted on such arrays are ideal for interrogation

176 phosphatidic acid (LBPA) in vivo, and can be reconstituted on supported bilayers in vitro.

177 osed to perform this cycloaddition have been reconstituted, only pyridine products have been isolated

178 nelles, to induce organelle contacts, and to reconstitute OSBP-VAP ER-Golgi tethering implicated in p

179 nic ovarian somatic cells to form xenogeneic reconstituted ovaries, which are cultured under an air-l

180 amics are coupled to downstream proteins, we reconstituted part of the bacterial cell division machin

181 nexpectedly, the PIC alone was sufficient to reconstitute pausing, suggesting RNAPII pausing is an in

182 Consistent with such a role, we reconstitute PG multi-enzyme complexes containing NlpI,

183 e lateral organization of cell membranes and reconstituted phospholipid bilayers; however, the mechan

184 eIF2.GTP.Met-tRNAi ternary complex (TC) from reconstituted PICs with a UUG start codon, indicating de

185 Reconstituted polyphenolic and aromatic fractions (PAFs)

186 We show here that reconstituted PRC1 readily phase-separates into droplets

187 Three mixtures were reconstituted proportionally to median concentrations fo

188 Using reconstituted proteasome complexes, we find that chain d

189 ins has been studied in vitro using purified reconstituted proteins or in CL synthesis knockout cells

190 n in both detergent-solubilised micelles and reconstituted proteoliposomes.

191 In this study, we reconstituted PTEN-deficient breast cancer cells with wi

192 We reconstitute purified monomeric ATP synthase from porcin

193 hese substitutions and deletions in vitro by reconstituting purified RD3 variants with GCAP1-activate

194 for Rab conversion in vivo and in vitro, and reconstitute Rab7 activation with yeast and metazoan pro

195 nterval learning, we demonstrate that sparse reconstituted rat hippocampal neural circuits are intrin

196 (+) LT-HSCs are lineage-balanced and stably reconstitute recipients.

197 lonRIalpha mice, as well as human cord blood-reconstituted reNSGS mice, which are immune-deficient, p

198 oli transcription elongation complexes block reconstituted replisomes.

199 e membrane-protein complexes, and used it to reconstitute Rhodobacter sphaeroides reaction center com

200 -MAP, in vitro microtubule dynamics assay to reconstitute robust plus-end-leading treadmilling, consi

201 We use an in vitro reconstituted Saccharomyces cerevisiae replisome to demo

202 om electrophysiological assays with membrane-reconstituted SDBC disclosed that it is a nonselective c

203 The reconstituted serotonergic regulation of sympathetic act

204 For each reconstituted serum mixture, its inhibitor-TTR dissociat

205 liver editing efficiency, thereby completely reconstituting serum F8 activity in a mouse model of hem

206 Here, we use a reconstituted single-vesicle fusion assay under physiolo

207 in can self-assemble in vitro and be used to reconstitute skin in vivo.

208 Reconstituted SNAREs are constitutively active, so a maj

209 We present a pipeline called RESPECTEx (REconstituting SPecific Cell-Type Expression) and use it

210 TMEM16K forms contact sites with endosomes, reconstituting split-GFP with the small GTPase RAB7.

211 Here, we reconstitute Staphylococcus aureus CP biosynthesis and e

212 glass surfaces and full-length constructs on reconstituted, supported lipid bilayers.

213 escribe measurements on full-length membrane-reconstituted synaptotagmin 1 using site-directed spin l

214 values did barely permit ATP synthesis in a reconstituted system containing purified yeast F(1)F(0)

215 Here, using a reconstituted system of defined peptide-exchange compone

216 This reconstituted system uncovers the role of the capsid in

217 Here, we utilized a reconstituted system with a defined set of signals to in

218 Using a reconstituted system with purified proteins from Sacchar

219 the same ECF module, but a minimal liposome-reconstituted system, required to substantiate this idea

220 single particle fluorescence microscopy in a reconstituted system.

221 the membrane and have enzymatic activity in reconstituted systems after truncation or modification o

222 is predicted to be natively unstructured, in reconstituted systems PopZ can self-assemble into a macr

223 Using biochemically reconstituted systems, we show that two transcription fa

224 ), however, whether successful DAA treatment reconstitute T follicular helper (T(FH))-B cell axis in

225 To quantify phagocytosis, the reconstituted target particles are incubated with macrop

226 (T1LCs) using long-term cultured xenogeneic reconstituted testes.

227 We reconstitute the 34 proteins needed to form the S. cerev

228 oenvironmental cues, human mini-brain models reconstitute the arrangement of structural tissues and s

229 lection are methods that can computationally reconstitute the complete transcriptome in partially-mea

230 Here, we reconstitute the disassembly of a collided polysome in a

231 rotein, cofilin, and AIP1) are sufficient to reconstitute the formation of cables that undergo polari

232 demonstrate that healthy donor HSPC not only reconstitute the hematopoietic system after transplantat

233 ould fully and glutamic acid could partially reconstitute the level of chloroquine/quinine resistance

234 Here, we reconstitute the linker for activation of T cells (LAT):

235 ; while horse and pig, but not rat, MLKL can reconstitute the mouse pathway.

236 neurons contact their peripheral targets and reconstitute the muscle spindle proprioceptive receptors

237 Here we successfully reconstitute the PC-1/PC-2 complex in the plasma membran

238 red BTNL8 expression but was insufficient to reconstitute the physiological Vgamma4(+)/Vdelta1(+) sub

239 possible in principle to fully biochemically reconstitute the sequential processes of HIV-1 assembly

240 In vitro, we reconstitute the SYD-2 and ELKS-1 liquid-phase scaffold,

241 Here, we in vitro reconstitute the venemycin PKS, a short assembly line th

242 lecular basis for tetherin counteraction, we reconstituted the AP-2 complex with a simian tetherin an

243 ne synthetase from Nocardia brasiliensis and reconstituted the biosynthetic pathway in vitro to link

244 Here, we reconstituted the Chlamydomonas reinhardtii RS head that

245 We have reconstituted the core machinery for regulating lipid sa

246 Here, we have reconstituted the FA pathway in vitro to study functiona

247 , plus two homologous DNA molecules, we have reconstituted the genetic recombination-initiated pathwa

248 properties of the receptor, we biochemically reconstituted the GLR3.3 ligand-binding domain (LBD) and

249 To test this idea, we have reconstituted the interactions between viperin, IRAK1, a

250 Here, we reconstituted the maturation of mitochondrial [4Fe-4S] a

251 Here, we reconstituted the patterning of the small GTPase Rab5 an

252 We reconstituted the PT reaction using purified DndCDE from

253 y is restricted by the lack of a system that reconstitutes the in-situactivation dynamics of quiescen

254 n in-cell assay in 384-well plates by stably reconstituting the FGF14:Nav1.6 complex using the split-

255 To this end, we generated chimeric motors by reconstituting the MHC fast isoform (MyHC-IId) and slow

256 sociated polyketide) aglycone by first fully reconstituting the NOCAP synthase in vitro from purified

257 d immunological non-responders (INR) fail to reconstitute their CD4 + T cell pool after initiation of

258 e purified cross-linked rhodopsin dimers and reconstituted them into nanodiscs for cryo-EM analysis.

259 y purifying 19 Escherichia coli proteins and reconstituting them in vitro in the presence of acetyl-C

260 rupted in these lines by CRISPR/Cas9, before reconstituting them with mutant and wild-type TRIF expre

261 We have reconstituted these membrane helices in model membranes

262 By reconstituting these processes with purified budding yea

263 )-dependent, in vitro motility parameters of reconstituted thin filaments (RTFs).

264 We developed an in vitro membrane system to reconstitute this process, to identify the essential pro

265 We reconstituted this "short NC" gp41 into a virus-mimetic

266 ne the mechanism of GCN2 activation, we have reconstituted this process in vitro, using purified comp

267 Collectively, we have elucidated and reconstituted three divergent pathways for the biosynthe

268 wo inactive fragments of TurboID that can be reconstituted through protein-protein interactions or or

269 Synthetic venom reconstituted through recombinant VST expression will ai

270 iNKT cells in bone marrow chimeras that reconstituted thymic cellularity developed beyond stage

271 er C-terminal domains that are necessary for reconstituted TNL cell death signaling.

272 ous lipids and coopted host factors, we have reconstituted Tomato bushy stunt virus (TBSV) replicase

273 on of electron cryo-microscopy (cryo-EM) and reconstituted translation initiation assays with native

274 we assayed Ski's activity using an in vitro reconstituted translation system and report that this co

275 By reconstituting translation in vitro using highly purifie

276 teins from Saccharomyces cerevisiae, we have reconstituted translesion synthesis (TLS)-mediated resta

277 hows that a minimal in vitro system with two reconstituted transporters recapitulates intricate kinet

278 Furthermore, the BRCA1-reconstituted tumor cells are more sensitive to the hist

279 We reconstituted two in vitro reactions targeting a pre-tra

280 The concentrated juice was reconstituted up to the original degrees Brix of the who

281 The membrane-reconstituted VcChiP channel was highly dynamic and volt

282 Here we use a reconstituted vesicle system to explore how PS influence

283 FokI-Cascade can be reconstituted via an optimized two-component expression

284 sion can be synchronized and controlled, and reconstituting viral fusion to synthetic membranes, whic

285 n of MS2 was significantly lower in both the reconstituted water samples and isolates compared to the

286 Those vectors were introduced in two reconstituted wines to assess whether simpler vectors co

287 of the CENP-A nucleosome core particle (NCP) reconstituted with a human alpha-satellite DNA derivativ

288 SECH treatments can clear HIV-1 in >50% mice reconstituted with a human immune system, as demonstrate

289 ductants and BTN3-deficient human 293T cells reconstituted with alpaca or human BTN3 or alpaca/human

290 re, cryo-EM data were derived from filaments reconstituted with alpha1-actin, cardiac alphaalpha-trop

291 n FRDA patient's lymphoblastoid cells stably reconstituted with frataxin, indicated HS-1-associated p

292 er NOD.Cg-Prkdc(scid) Il2rgt(m1Wjl)/SzJ mice reconstituted with human hematopoietic stem cells (Hu-NS

293 elia burgdorferi infection in humanized mice reconstituted with human hematopoietic stem cells from d

294 ficantly greater when IQGAP1-null cells were reconstituted with IQGAP1 Y1510A than when cells were re

295 , we employed a biochemically defined system reconstituted with recombinant KMT2 core complexes (KMT2

296 paired in virus release and are rescued when reconstituted with wild-type Lyn, but not a kinase- or p

297 AP1, and mouse embryonic fibroblasts [MEFs]) reconstituted with wild-type or phosphorylation mutant f

298 uted with IQGAP1 Y1510A than when cells were reconstituted with WT IQGAP1.

299 We studied the convergence of reconstituted yeast replication forks that include all c

300 First, we use an in vitro reconstituted yeast translation system to demonstrate th