ライフサイエンスコーパス: recurrently

1 f MAX-interacting proteins, was also deleted recurrently.

2 95,843 circRNAs, of which 20,441 were found recurrently.

3 systems behaviors that have been discovered recurrently across signaling networks.

4 s the consequence of allergen exposures that recurrently activate memory B cells and identify these a

5 alf of all GWAS CRC risk loci co-localize to recurrently activated enhancers.

6 Of the enhancers highly recurrently activated in CRC, most are constituents of s

7 These mutations recurrently affect specific amino acid residues, leading

8 he focus has shifted to pinpointing the loci recurrently affected by LOH events across multiple tumor

9 osses in 13q32.3-q34, we identified 47 genes recurrently affected by protein-changing mutations (each

10 We search for genes that are recurrently affected by rare variants (minor allele freq

11 r coactivators (SRCs; SRC-1, -2 and -3) were recurrently affected by these SiM-miRNAs.

12 In 35 NMZL patients, 41 genes were found recurrently affected in >/=3 (9%) cases, including highl

13 genetic mechanism by which PP2A function is recurrently affected in human cancer, involving haploins

14 Cancer Gene Census genes, many of which were recurrently affected in the set of 25 immortalized cell

15 pectively, with MEN1, PSIP1 and ARID1A being recurrently affected.

16 ified chromothripsis in 5 HCC genomes (5.7%) recurrently affecting chromosomal arms 1q and 8q.

17 ules by three criteria: (1) Member genes are recurrently altered across a set of tumor samples; (2) m

18 A subset of genes was recurrently altered across tumors derived from different

19 Further, nine recurrently altered genes in passaged D. rerio T-ALL wer

20 WGS and WES identified novel mutations in recurrently altered genes not previously implicated in T

21 lymphoma (DLBCL) have identified hundreds of recurrently altered genes.

22 brafish and 61 human samples), 10 genes were recurrently altered in > 3 zebrafish cancers and >/= 4 h

23 enomics approach identified cancer hallmarks recurrently altered in human HCC that may be targeted by

24 in several genes not previously known to be recurrently altered in SMZL.

25 l patterns of putative driver genes that are recurrently altered in these tumors by investigating dif

26 nd somatic copy number variations identified recurrently altered mechanisms of carcinogenesis: chroma

27 ng and noncoding alteration and identify ten recurrently altered pathways, with associations between

28 161 putative driver genes associated with 11 recurrently altered pathways.

29 Transcriptional regulators are recurrently altered through translocations, deletions, o

30 Our analysis identified 29 recurrently amplified and 22 recurrently deleted regions

31 RNA interference library targeting 369 genes recurrently amplified and overexpressed in both ERBB2-am

32 screen we assessed whether genes found to be recurrently amplified and overexpressed in ERBB2+ve brea

33 associated factor 2), as an oncogene that is recurrently amplified and rearranged in 15% of human epi

34 , which is the ligand for the BMP family, is recurrently amplified and transcriptionally upregulated

35 RB2-associated binding protein 2 (GAB2) as a recurrently amplified gene that potently transforms immo

36 alysis of human cancers showed that PHGDH is recurrently amplified in a genomic region of focal copy

37 e antiapoptotic BCL2 family member BCL2A1 is recurrently amplified in approximately 30% of melanomas

38 There are several, recurrently amplified oncogenes throughout the human gen

39 zebrafish melanoma model to test genes in a recurrently amplified region of chromosome 1 for the abi

40 creens to pinpoint driver genes within large recurrently amplified regions of DNA.

41 Complex rearrangements occur recurrently and are associated with amplification of TER

42 rogramming of somatic stem cells to produce, recurrently and reversibly, a bewildering array of diffe

43 eage; and (iv) MUC7 PTS-repeats have evolved recurrently and under adaptive constraints.

44 phisms (STRPs), which can mutate rapidly and recurrently, and SNPs in 721 regions across the human ge

45 Recurrently appearing post-chemotherapy mutations are ra

46 Bs in P. autumnale probably form recurrently as by-products of the extensive genome restr

47 matic structural variant (SSV) breakpoint is recurrently associated with altered expression or DNA me

48 aberration and showed this aberration to be recurrently associated with morphologic and clinical fea

49 apply this method to identify CNVs that are recurrently associated with postglacial adaptation of ma

50 This process operates recurrently at discrete genomic regions and generates dr

51 and observed that the genetic adaptation was recurrently based on a strategic mutation that changed t

52 ation using the cghMCR method and identifies recurrently broken genes that may be disrupted or fused.

53 However, one undisputable observation recurrently confirmed during influenza seasons of the la

54 bursting cells and regular firing cells are recurrently connected among themselves but connections b

55 Theoretical studies indicate that recurrently connected auto-associative or discrete attra

56 ed input patterns arriving onto dendrites of recurrently connected CA3 neurons.

57 Before vision, a transient network of recurrently connected cholinergic interneurons, called s

58 nsists of a functionally columnar network of recurrently connected excitatory and inhibitory neural p

59 te-and-fire neurons with synaptic delays and recurrently connected inhibitory interneurons.

60 this, it induces global structures within a recurrently connected network.

61 e persistent activity hypothesis, holds that recurrently connected neural networks, presumably locate

62 a neuronal network model that represents two recurrently connected neural systems.

63 In addition, L4 recurrently connected neurons were driven by thalamocort

64 e how these concepts could be implemented by recurrently connected probabilistic population codes.

65 yeless/Pax6 regulates the development of two recurrently-connected CX subtypes: Eyeless loss simultan

66 Here, we present converging evidence that recurrently-connected piriform populations stabilize sen

67 en pairwise correlations and firing rates in recurrently coupled excitatory-inhibitory spiking networ

68 Recurrently coupled networks of inhibitory neurons robus

69 RNAs) targeting the mouse orthologs of genes recurrently deleted in a series of human hepatocellular

70 thus directly bind and inhibit K-Ras and are recurrently deleted in human cancer.

71 ate genes present within chromosomal regions recurrently deleted in human cancers, we coupled high-re

72 s identified 29 recurrently amplified and 22 recurrently deleted regions with a high level of copy nu

73 , Nf1, Flt3, Cbl, Notch1 and Mll2, which are recurrently deleted/mutated in human haematological mali

74 The expression patterns of 917 recurrently deregulated lncRNAs are correlated with clin

75 Many recurrently deregulated lncRNAs are enriched in co-expre

76 ), and CARD11 gain-of-function mutations are recurrently detected in human diffuse large B-cell lymph

77 MIR142 mutations have been recurrently detected in IDH-mutated AML samples.

78 Only RAS mutations were recurrently detected in patients and found to be associa

79 ding activities of novel RBPs that have been recurrently detected in the RNA interactomes of multiple

80 ci with aberrant copy numbers and identified recurrently disrupted genes in genomically unstable canc

81 ve identified many de novo mutations but few recurrently disrupted genes.

82 mutation analysis showed that 63 miRNAs were recurrently disrupted in DLBCL, including highly express

83 lation of KIT-MAPK signaling also feature as recurrently disrupted pathways.

84 rticipating in known human CRC pathways were recurrently disrupted, indicating that these pathways mi

85 g., sticklebacks, cichlids, and whitefishes) recurrently diverge toward slender-bodied pelagic forms

86 Mating system shifts recurrently drive specific changes in organ dimensions.

87 Numerous 2OGDDs are recurrently dysregulated in cancer.

88 the Hedgehog (Hh) signaling pathway are each recurrently dysregulated in many types of human cancer.

89 entify pairs of metabolic genes which may be recurrently dysregulated.

90 not accidental, and may be explained by the recurrently elevated physical and biological activity of

91 cer recurrence signaled by a persistently or recurrently elevated prostate-specific antigen (PSA) lev

92 specific T(regs) (termed MJ23 T(regs)) found recurrently enriched in the tumors of mice with oncogene

93 nalysis suggests that one of the viral types recurrently evolved at least four times in the past ~30,

94 Such autoimmune risk alleles have recurrently evolved at the DANGEROUS MIX2 (DM2) nucleoti

95 c chromosomes in meiotic prophase provides a recurrently evolving trigger for the meiotic arrest of i

96 cific instance of such a model, in which two recurrently excited populations of neurons compete for h

97 The expansion occurred recurrently, explaining the seemingly non-mendelian inhe

98 lmer amaranth and waterhemp populations were recurrently exposed to herbicide drift in a wind tunnel

99 scripts to support a viral etiology of SS or recurrently expressed gene fusions, but it did identify

100 B1 (Ribosomal protein S6 kinase beta-1) were recurrently expressed in a number of breast tumor cell l

101 Four out of nine transcripts were found recurrently expressed in an extended panel of primary TG

102 Many of these patients were rehospitalized recurrently for a problem in the same organ system.

103 6 originated independently, including 4 ENCs recurrently formed at the same position in not closely r

104 Approximately 20 genes are recurrently found as mutated in CH, indicating they conf

105 roteins involving Nucleoporin 98 (NUP98) are recurrently found in acute myeloid leukemia (AML) and ar

106 isorder Coffin-Siris syndrome (CSS), and are recurrently found in cancers.

107 While some such mutations are recurrently found in many tumors, many others exist sole

108 One mutation (R96L) was recurrently found in three ethnically diverse families w

109 serine cluster (residues 271, 273, and 275) recurrently found to be phosphorylated in both human and

110 e explanation as to the reason that RUNX1 is recurrently found translocated to ETO family members, wh

111 ) Project to determine recurrent fusions and recurrently-fused genes within different brain tumor his

112 as a comparator, we identify enhancers with recurrently gained or lost activity across CRC specimens

113 e identified 12 expression programs that are recurrently heterogeneous within multiple cancer cell li

114 it is becoming apparent that these mutations recurrently hijack the same hallmark molecular pathways

115 siological changes), and 13 fall within loci recurrently hit by copy number variants.

116 me-wide significance; however, 16 genes were recurrently hit by protein-truncating DNMs, correspondin

117 However, cIAP1 and cIAP2 are recurrently homozygously deleted in multiple myeloma (MM

118 contributes to counterregulatory failure in recurrently hypoglycemic (RH) and diabetic rats.

119 During hypoglycemia, recurrently hypoglycemic rats exhibited a 49-63% reducti

120 mic extracts that high-intensity exercise in recurrently hypoglycemic rats increases levels of a numb

121 carboxylase (GAD), in the VMH of control and recurrently hypoglycemic rats.

122 Overall, 76 gene body promoters were recurrently hypomethylated, including TERT and the oncog

123 EGFR activation has been recurrently identified in a set of vemurafenib-resistant

124 ogenic signaling output of various mutations recurrently identified in human tumors.

125 antly moderated neuroanatomical diagnosis as recurrently-ill patients had higher misclassification ra

126 Importantly, the EZH2(Y641) mutants recurrently implicated in lymphoma pathogenesis are unab

127 induced by NF-kappaB2 mutations, which occur recurrently in a variety of human lymphoid malignancies.

128 s promoted by homologous recombination occur recurrently in humans and great apes and they are not ta

129 at grouping and segmentation are implemented recurrently in humans, and show that CapsNets reproduce

130 53, and NOTCH1, mutations were also observed recurrently in MEF2B, TRAF2, and TET2.

131 are bioactive metabolites that have evolved recurrently in plants, presumably for defense.

132 ny structural variations were shown to occur recurrently in the population.

133 rovide additional evidence that HGT occurred recurrently in this yeast lineage and was crucial for th

134 Our findings define PARD3 as a recurrently inactivated cell polarity regulator in LSCC

135 nal (PSS) sequences at their breakpoints and recurrently inactivated tumor-suppressor genes.

136 ation of both strands of miR-30a and miR-145 recurrently increased cell cycle pathway genes and signi

137 etic alterations and genomic profiles, which recurrently involve multiple signaling pathways, have be

138 conserved phylogenetically, while others are recurrently involved in chromosomal rearrangement, resul

139 We present the discovery of genes recurrently involved in structural variation in nasophar

140 genes in endometrial stromal tumors, is also recurrently involved in the pathogenesis of OFMTs, irres

141 ations in genes not previously recognized as recurrently involved in Wilms tumors, the most frequent

142 Rociletinib resistance recurrently involves MET, EGFR, PIK3CA, ERRB2, KRAS and

143 eptibility testing (AST) when an organism is recurrently isolated from the same specimen source.

144 ximate quantities, or number sense, has been recurrently linked to mathematical skills, although the

145 D1) and 14q (including DICER1 and AKT1) were recurrently lost in HPV-positive OSCCs, in contrast to t

146 altered in PanINs and tumors, but few other recurrently modified genes were detected.

147 Dependent colony foundation (DCF) evolved recurrently multiple times across the ants, bees, and wa

148 /or lymphoma-associated genes, and nine were recurrently mutated (DNMT3A, TET2, JAK2, ASXL1, TP53, GN

149 nd only a few genes (TP53, ATRX, RB1) highly recurrently mutated across sarcoma types; (2) within sar

150 However, the specific genes recurrently mutated as a consequence of BRCA1 dysfunctio

151 disclosed that the NOTCH1 proto-oncogene is recurrently mutated at CLL presentation.

152 e fewer genetic lesions overall and no known recurrently mutated cancer consensus genes.

153 n Braf(V600E) mutant mice and identify 1,232 recurrently mutated candidate cancer genes (CCGs) from 7

154 sites in the SB-induced tumors identified 45 recurrently mutated candidate cancer genes.

155 Analysis of these data reveals recurrently mutated driver genes shared between species

156 The SRE includes a recurrently mutated enhancer whose activity is also affe

157 s in CEBPZ, suggesting that CEBPZ is a novel recurrently mutated gene in AML.

158 ltraviolet pathogenesis and discovered a new recurrently mutated gene in melanoma.

159 CDK12 is a recurrently mutated gene in serous ovarian carcinoma, wh

160 In addition to discovering novel, recurrently mutated genes (for example, WAC, SMC3, DIS3,

161 Here we identify 44 recurrently mutated genes and 11 recurrent somatic copy

162 tical models to disentangle the effect of 12 recurrently mutated genes and 4 cytogenetic alterations

163 We identified recurrently mutated genes and assessed clonal structure

164 Distribution of recurrently mutated genes and clonal architecture differ

165 tumor cells, we identified additional novel recurrently mutated genes and confirmed mutations of one

166 have enabled the identification of a set of recurrently mutated genes central to the pathogenesis of

167 Screening of recurrently mutated genes in 48 additional FR-CLLs revea

168 ed the coding regions or hotspot areas of 68 recurrently mutated genes in a cohort of 664 patients ag

169 k and single-cell-targeted sequencing of MDS recurrently mutated genes in CD34+ progenitors (and dysp

170 al PCR to broadly measure mutated alleles of recurrently mutated genes in CR marrows of AML patients

171 Unexpectedly, the majority of recurrently mutated genes in EAC were also mutated in ND

172 We report the identification of 15 novel recurrently mutated genes in FL.

173 omic sequencing studies have identified many recurrently mutated genes in human SCLC tumors.

174 FAM46C is one of the most recurrently mutated genes in multiple myeloma; however i

175 Recurrently mutated genes in myelodysplastic syndrome (M

176 cted before HSCT for somatic mutations in 34 recurrently mutated genes in myeloid neoplasms.

177 Screening for recurrently mutated genes in the mononuclear cell fracti

178 0.60 per Mb (0.48 nonsilent) and notably few recurrently mutated genes in these tumors.

179 % of mutations were seen in both groups, and recurrently mutated genes include NRAS, KRAS, BRAF, and

180 shing cancer-driving genes from thousands of recurrently mutated genes remains a significant challeng

181 creatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathway

182 exome sequencing (WES) of 47 tumors revealed recurrently mutated genes that included KDR, TP53, and P

183 ematological malignancies identified several recurrently mutated genes that may be disease initiators

184 We identified recurrently mutated genes that showed positive associati

185 H (cnLOH) together with sequence analysis of recurrently mutated genes to characterize paired AML gen

186 Recurrently mutated genes were investigated by targeted

187 nes, which are shown to interact with highly recurrently mutated genes yet have been ignored by conve

188 is revealed significant correlations between recurrently mutated genes, as well as genotype-phenotype

189 nic DNA from prostate cancers has identified recurrently mutated genes, but the spectrum of genome-wi

190 ondary-AML samples contained mutations in 11 recurrently mutated genes, including 4 genes that have n

191 While ICC and HCC share recurrently mutated genes, including TP53, ARID1A, and A

192 residues, rather than methods that identify recurrently mutated genes, may uncover new biologically

193 tations outside of these previously reported recurrently mutated genes.

194 n pattern, sharing only one of their 15 most recurrently mutated genes.

195 No exome-sequenced TMD/AMKL sample had other recurrently mutated genes.

196 f cancer driver genes, although enriched for recurrently mutated genes.

197 MML carried at least 1 somatic mutation in 9 recurrently mutated genes.

198 aracterized by low mutational burden and few recurrently mutated genes.

199 Genomic studies have identified a number of recurrently mutated genes; in order of descending freque

200 A total of 30 genes were recurrently mutated in >=3% of the cohort.

201 Additionally, 40 amino acid sites were recurrently mutated in 36 genes, and targeted sequencing

202 the human homologue, SETD2, was found to be recurrently mutated in a significant percentage of renal

203 JAK1 and JAK3 are recurrently mutated in acute lymphoblastic leukemia.

204 decades have identified many genes that are recurrently mutated in acute myeloid leukemia (AML).

205 It was recurrently mutated in advanced human cancers and signif

206 equently harbored somatic mutations in genes recurrently mutated in AML or myelodysplastic syndromes

207 these, an average of 5 are in genes that are recurrently mutated in AML.

208 ssor gene, joining the growing list of genes recurrently mutated in AML.

209 It is now clear that many genes are recurrently mutated in AML; moreover, individual leukemi

210 Finally, we report that KLHL6, which is recurrently mutated in B cell lymphomas, is an off-targe

211 We identified 70 genes that were recurrently mutated in Burkitt lymphomas, including ID3,

212 atically identify noncoding regions that are recurrently mutated in cancer.

213 luding the cohesin complex member STAG2, are recurrently mutated in cancer.

214 we identify to be essential for cohesion, is recurrently mutated in chronic lymphocytic leukaemia.

215 SF3B1 is recurrently mutated in chronic lymphocytic leukemia (CLL

216 Mutations in genes that are recurrently mutated in de novo AML were underrepresented

217 he screen with a panel of 264 genes that are recurrently mutated in de novo AML, we identified rare,

218 throughput functional interrogation of genes recurrently mutated in DLBCL.

219 locus has previously been demonstrated to be recurrently mutated in GCB DLBCL; the transcriptional si

220 r mutations, and in 31 nodules, for 10 genes recurrently mutated in HCC.

221 nsertions or deletions in 160 genes that are recurrently mutated in hematologic cancers.

222 tion sequencing (NGS) of a panel of 28 genes recurrently mutated in hematologic malignancies in a coh

223 ploinsufficient transcription factor that is recurrently mutated in hematopoietic and solid tumors.

224 hese data extend the range of genes that are recurrently mutated in high-risk childhood B-precursor a

225 a specific codon; the corresponding codon is recurrently mutated in human cancer.

226 onarily conserved residues in SETD2 that are recurrently mutated in human cancers.

227 vel genes, isocitrate dehydrogenase (IDH) is recurrently mutated in intrahepatic cholangiocarcinomas.

228 In addition, the human KAT6 HATs are recurrently mutated in leukemia and solid tumors.

229 is regard, recent studies on TBL1XR1, a gene recurrently mutated in MCD/C5s and PENLs, suggest that a

230 The NFE2L2-KEAP1 and MLL pathways are recurrently mutated in multiple cohorts of HCC.

231 argeted next-generation sequencing for genes recurrently mutated in myeloid malignancies in patients

232 e further identified a number of novel genes recurrently mutated in patients with MCL including RB1,

233 Recurrently mutated in primary and metastatic prostate t

234 identified 322 DLBCL cancer genes that were recurrently mutated in primary DLBCLs.

235 subunit of a Polycomb repressor complex, is recurrently mutated in several forms of cancer and is hi

236 r focused on drugging gene products that are recurrently mutated in specific cancer types.

237 mon gamma chain of cytokine receptors and is recurrently mutated in T-cell acute lymphoblastic leukem

238 CREB binding protein (CREBBP) and EP300 are recurrently mutated in the activated B cell-like and ger

239 tations identified were in genes known to be recurrently mutated in the tumor type tested.

240 While few non-coding genomic elements are recurrently mutated in this cohort, we identify 93 genes

241 sucrose nonfermentable (SWI/SNF) complex are recurrently mutated in tumors, suggesting that altering

242 performance of these two tests, we simulated recurrently mutated loci each flanked by sites with neut

243 n RNA processing genes, ribosomal genes, and recurrently mutated MDS and acute myeloid leukemia-assoc

244 TAM model, we tested loss-of-function of 22 recurrently mutated ML-DS genes.

245 to the identification of many driver genes, recurrently mutated more than expected.

246 We sequenced 40 recurrently mutated myeloid malignancy genes in tumor DN

247 precise metabolic vulnerability imposed by a recurrently mutated oncogene.

248 rved the expected patterns of mutation, with recurrently mutated positions for oncogenes and evenly d

249 eveloped a statistical algorithm to identify recurrently mutated residues in tumor samples.

250 c locus-specific mutation rates, we identify recurrently mutated sites across individuals with cancer

251 omas by mutation signatures and identify ten recurrently mutated UVR signature genes that predict pat

252 ning homologous chromosome, however, are not recurrently mutated, and the identity of key 8p tumor-su

253 tion of tumours has uncovered numerous genes recurrently mutated, deleted or amplified, but gene fusi

254 %), KRAS (26%), TP53 (26%) and SOX8 (19%), a recurrently-mutated gene previously unreported in EnOC.

255 One is the total number of mutants at a recurrently mutating locus among sampled sequences, whic

256 ven the states of the sampled sequences at a recurrently mutating locus and an incompletely resolved

257 inutes, 15.6% (24 of 154) of treated lesions recurrently narrowed by more than 50%, with a majority o

258 Several CNAs recurrently observed in primary tumors gradually disappe

259 Recurrently observed loss-of-function mutations were ass

260 d death-1 (PD-1) ligands PD-L1 and PD-L2 are recurrently observed.

261 The FBXW7 mutations recurrently occur in a specific codon; the corresponding

262 rement to consider the effect of the various recurrently occurring genetic lesions in AML on the init

263 of genes reveals human orthologs known to be recurrently overexpressed and/or amplified in tumors.

264 gulated lncRNA 1 (BANCR) was identified as a recurrently overexpressed, previously unannotated 693-bp

265 Overall, myelination-related processes were recurrently perturbed in multiple cell types, suggesting

266 the serine at codon 34 (Ser34) in U2AF1 was recurrently present in 13 out of 150 (8.7%) subjects wit

267 The human brain recurrently prioritizes task-relevant over task-irreleva

268 They may have recurrently produced favourable deep-water formation con

269 studies of C-T-C circuits, thus suggest that recurrently projecting thalamocortical neurons are the p

270 effectiveness of such a process, it has been recurrently proposed that a remote coupling with LO phon

271 ene encoding the transcription factor ERG is recurrently rearranged and plays a critical role in pros

272 breakage under replication stress conditions recurrently rearranged in cancer.

273 D7 fusion genes, indicating that CHD7 may be recurrently rearranged in this disease.

274 In addition, HLXB9 is recurrently rearranged in young children with acute myel

275 ular level, ranging from gene families being recurrently recruited to identical amino acid replacemen

276 f the transcriptome varied significantly and recurrently, reflecting large, reproducible cell-state t

277 epeatedly and recently colonised CTVT cells, recurrently replacing incumbent CTVT haplotypes.

278 However, many recurrently reported properties, such as the spatial clu

279 In particular, TE-derived proteins have been recurrently repurposed as part of defense systems that p

280 encoding NLR plant immune receptor genes are recurrently responsible for hybrid necrosis, highlightin

281 immunodeficiency virus (HIV), others may be recurrently risky.

282 Associated features that were recurrently seen in these individuals included hypotonia

283 red clover (Trifolium pratense L.) that were recurrently selected for 2,4-D resistance to detect geno

284 identified somatic hypermutations that were recurrently selected in such public clonotypes, indicati

285 breather(15), in which vibrational energy is recurrently shared among several resonance modes-dynamic

286 RB1, SMAD4, HRAS, APC, PIK3CA and GNAQ were recurrently somatically altered in SDC.

287 NF1 was the only gene that was recurrently somatically inactivated in multiple tumors.

288 ductivity and fitness in tolerant species in recurrently stressed environments.

289 y genes in DNA repair and oncogenic pathways recurrently subject to MSI and uncover non-coding loci t

290 Here, we show that STING signaling is recurrently suppressed in melanoma cells, where this eve

291 dulators or members of the NOTCH pathway are recurrently targeted by genetic lesions in SMZL; these i

292 Our analysis defines 96 genomic regions recurrently targeted by homozygous deletions.

293 mic deletions, mutations, and rearrangements recurrently targeted genes encoding components of the SW

294 otein kinase (MAPK) components are recruited recurrently to transduce signals of different origins, a

295 es and identify 23 genomic regions that have recurrently toggled between a direct and an inverted sta

296 A rush followed to identify recurrently translocated genes in all types of cancer, w

297 Among the three TET genes, TET2 recurrently undergoes inactivating mutations in a wide r

298 ed research, the value of animal research is recurrently undermined.

299 Chemists recurrently utilize "fuzzy" chemical concepts (e.g. atom

300 goal-oriented motor behavior is regulated by recurrently wired sensory-motor neurons.