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1 ajor phosphatase revealed that the enzyme is redox sensitive.
2 re prevented, suggesting that the pathway is redox-sensitive.
3 smooth muscle, have certain members that are redox-sensitive.
4 neither the AP1/Ets regulatory sites nor the redox sensitive (-1607/2G) site in MMP-1 promoter are in
6 substrate-binding domain of FBXL5 contains a redox-sensitive [2Fe-2S] cluster that, upon oxidation, p
7 rombogenicity through angiotensin II-induced redox-sensitive activation of mitogen-activated protein
10 hypoxia may have an independent influence on redox-sensitive adaptive responses to exercise and exerc
11 sformation may be mediated, in part, through redox-sensitive AKT signal transduction pathways by up-r
12 g the crucial role of these highly conserved redox-sensitive amino acid residues for P-protein activi
15 idative stress response that reactivates the redox-sensitive AMPK and activates the redox-sensitive s
17 or barrier to a cure for AIDS is exquisitely redox sensitive and could be selectively targeted by Trx
20 on also led to oxidative inactivation of the redox-sensitive and ERK-specific phosphatase, DUSP3/VHR,
21 suggest that ubiquitination of lung ENaC is redox-sensitive and may have significant implications fo
22 Zn/Fe(T) (where Fe(T) = Fe(2+) + Fe(3+)) is redox-sensitive and retains a memory of the valence stat
24 Two novel prodrug polymers POEG-b-PSSDas (redox-sensitive) and POEG-b-PCCDas (redox-insensitive),
25 t mTORC2 complex stability and activation is redox sensitive, and further defined a novel role for p2
26 oderm: since the activity of bZIP factors is redox sensitive, and the initial polarization of oral vs
27 Zn(2+)-LpxC, the activity of Fe(2+)-LpxC is redox-sensitive, and a time-dependent decrease in activi
29 vide novel insights for targeting endogenous redox-sensitive antioxidant pathways to ameliorate the d
30 , and sequence analyses, we propose that the redox-sensitive APSK evolved after bifurcation of the su
32 anges cellular metabolism and thus activates redox-sensitive as well as oxygen-dependent signal trans
34 or TXNIP increases catalytic activity of the redox-sensitive ATG4B cysteine endopeptidase, leading to
39 related ODA light chains LC3 and LC5 and the redox-sensitive Ca2+ -binding subunit of the docking com
40 cal production as measured by Quest MRI, and redox-sensitive calcium dysregulation as measured by man
43 ere we report that TRPM2, a nonselective and redox-sensitive cation channel, inhibited ROS production
46 DX-FTR-TRXs pathway allows the regulation of redox-sensitive chloroplast enzymes in response to light
47 tric oxide (NO) synthesis, eNOS requires the redox-sensitive cofactor tetrahydrobiopterin (BH(4)); ho
48 er the speciation, and thus the mobility, of redox-sensitive contaminants including Cr(VI) is of grea
49 " moieties, polyethylene glycol (PEG) units, redox-sensitive cross-linker, and tumor-specific targeti
50 f alternate functional motifs such as 'KGD', redox-sensitive Cys and hydrophobic Trp/Phe residues arg
51 TRPA1 activation was dependent on essential redox-sensitive cysteine and lysine residues within N-te
52 hydrophobic clamp, including insertion of a redox-sensitive cysteine pair, confirms the importance o
53 ole in the phosphorelay signaling, where its redox-sensitive cysteine residue may provide additional
54 the C797S variant, confirming Cys-797 as the redox-sensitive cysteine residue that regulates kinase a
55 eukaryotic protein kinases, is regulated by redox-sensitive cysteine residues in the kinase domain.
57 ochemically, confirming that the C-terminal, redox-sensitive cysteine residues reside within the inte
58 ures of the Aurora A kinase domain delineate redox-sensitive cysteine residues that, upon covalent mo
64 other cellular components through energy- or redox-sensitive cytosolic kinase signalling and transcri
65 try and secondary ion mass spectrometry) and redox-sensitive detrital grains--reveal that the origina
66 te that CopZ has a strong propensity to form redox-sensitive dimers via two conserved cysteine residu
67 (D,L-lactide-co-glycolide) polymeric core by redox-sensitive disulfide bond, while TET was physically
69 so reveals the presence of a solvent-exposed redox-sensitive disulphide bridge, unique among the subt
71 scovered that a colorimetric sensor array of redox sensitive dyes can detect even very low levels of
72 ts and mitochondrial membrane potential- and redox-sensitive dyes are used to define RSV's impact on
75 gII-activated sources of ROS, the downstream redox-sensitive effectors, Ang-(1-7)-stimulated increase
76 s an integrated redox "hub" linking upstream redox-sensitive effects of BH4 and glutathione with redo
79 l iron may control the sorption mechanism of redox sensitive elements on the surface of clay minerals
80 ed the co-occurrence of four health-relevant redox-sensitive elements (U, As, V, and Cr) in 1494 grou
82 monstrates a degree of co-occurrence between redox-sensitive elements, which may pose additional risk
83 channels to H2S required the presence of the redox-sensitive extracellular residue H191, which is als
84 hibitory action requires the presence of the redox-sensitive, extracellular region of the channel whi
86 e oxygen species (ROS) were detected using a redox-sensitive fluorescent dye, a cytochrome c reductio
87 In this issue, Merksamer et al. exploit a redox-sensitive fluorescent protein to monitor the envir
91 to evaluate in vivo RBC redox status using a redox sensitive GFP (roGFP2) sensor under control of a b
92 by a redox-based topology assay (ReTA) with redox-sensitive GFP and confirmed by a protease protecti
94 geted viral gene transfer vectors expressing redox-sensitive GFP fused to sensor domains to measure H
98 itoPark mice), at the same time expressing a redox-sensitive GFP targeted to the mitochondrial matrix
99 n this study, we describe a system that uses redox-sensitive GFP to nondisruptively measure real-time
100 uence the redox status of cells, we utilized redox sensitive GFP2 (roGFP2) to determine the redox sta
101 2)) augments cellular ROS as detected by the redox-sensitive green fluorescent protein (roGFP) but do
103 orff-perfused hearts based on the use of the redox-sensitive green fluorescent protein 2, coupled to
104 iol redox status by mitochondrially targeted redox-sensitive green fluorescent protein and measuremen
105 g of the hepatic GSH redox potential using a redox-sensitive green fluorescent protein biosensor show
107 ings were corroborated by measurements using redox-sensitive green fluorescent protein, another prote
108 ) cytosolic oxidation (e.g. oxidation of the redox-sensitive Green fluorescent protein2 probe), (3) a
109 from the development of genetically encoded redox-sensitive green fluorescent proteins (roGFPs), whi
111 suggest that 6-TGNP can also react with the redox-sensitive GXXXCGK(S/T)C and GXXXXGK(S/T)C motif of
112 rn reacts with the Cys(20) side chain of the redox-sensitive GXXXCGK(S/T)C motif of RhoC to produce a
114 Loss of NRF2 decreased the expression of the redox-sensitive histone deacetylase, HDAC4, resulting in
116 nder gene mutations in MDSs license a common redox-sensitive inflammasome circuit, which suggests new
118 A cysteine-null mutant FKBP12.6 retained redox-sensitive interaction with RyR2, suggesting that t
123 situ equilibrium redox titrations and thiol redox-sensitive labeling studies showed that the gamma s
124 involvement of the Trx1 inhibitor Txnip as a redox-sensitive ligand of NLRP3 as previously proposed.
125 llular compartments, influence the status of redox-sensitive macromolecules, and protect against oxid
126 ion of their potential for use in assembling redox-sensitive magnetic resonance imaging contrast agen
129 ubiquitin-mediated degradation by Keap1 in a redox-sensitive manner through modifications of distinct
130 e 15-Lox1-15(S)-HETE axis activates EGFR via redox-sensitive manner, which in turn mediates Src-Jak2-
133 s of F. tularensis prevent the activation of redox-sensitive MAPK signaling components, NF-kappaB sig
135 tive stress induced microglia activation and redox-sensitive matrix metalloproteinase 9 (MMP9) stimul
136 tivity, thereby raising the possibility that redox-sensitive mechanisms underlie amino acid-dependent
139 ry direct evidence of crystallization from a redox-sensitive metallic liquid phase in the deep mantle
140 ns of Hg and lesser amounts of As, and other redox sensitive metals to groundwater and surface water.
141 record expansion of the oceanic inventory of redox-sensitive metals and the growth of the marine sulp
143 s with low affinity for organic matter, some redox-sensitive metals, and some metals with exceptional
144 agation of the reaction front is retarded by redox-sensitive mineral dissolution reactions and carbon
145 ic determinants of 2-OG levels, we uncover a redox sensitive mitochondrial lipoylation pathway, depen
146 CHCHD4, which is the central component of a redox-sensitive mitochondrial intermembrane space import
147 e to oxidative stress and identified a novel redox-sensitive mitochondrial TXNIP-Trx2-ASK1 signaling
148 oxidative stress, our studies focused on the redox-sensitive mitogen-activated protein kinase kinase
149 The small heat-shock protein HSP27 is a redox-sensitive molecular chaperone that is expressed th
150 es a previously undefined mechanism by which redox-sensitive molecules signal via apoptotic pathways
155 t the TSC complex plays an important role in redox-sensitive mTORC1 regulation and argues for the act
157 alters the abundance and oxidation state of redox-sensitive multiple proteins and that these changes
160 mediated production of ROS and activation of redox-sensitive NF-kappaB were PKCdelta dependent, sugge
161 hly regulated defense systems, including the redox sensitive Nrf2-Keap1 signaling pathway involved in
162 uclear factor-kappaB p65, a component of the redox-sensitive nuclear transcription factor nuclear fac
166 ever, the geochemical behavior of this toxic redox-sensitive oxyanion in anoxic environments is poorl
167 unx2 in diabetes mellitus is regulated via a redox-sensitive pathway that involves a direct interacti
168 s induced by air pollution are activation of redox-sensitive pathways and a role for antioxidants in
169 and adipose tissue/adipocytes and focused on redox-sensitive pathways, Rho kinase activity, and prote
172 inducing MAPK p38alpha, belong to a group of redox-sensitive phosphatases (protein tyrosine phosphata
175 ed hydrogen peroxide, activation of vascular redox-sensitive PKG-1, and downregulation of Rho kinase
176 g flow cytometry, oxidative stress using the redox-sensitive probe dihydroethidium, tissue factor act
178 obial denitrification (and potentially other redox-sensitive processes) that could improve water qual
179 s upon IL-4 treatment suggests more than one redox-sensitive protein implicated in this pathway.
180 nd protein interaction "social network" of a redox-sensitive protein in cells with high temporal reso
181 decreased thrombin-induced activation of the redox-sensitive protein kinases (Janus kinase 2, Akt, an
183 ication of specific cysteine residues within redox-sensitive protein targets, including Cys797 in the
186 mediated post-translational modifications of redox-sensitive proteins are postulated as a key mechani
188 essential E. coli genes encode one-third of redox-sensitive proteins, a finding that might explain t
190 n is largely dependent on the development of redox-sensitive proxies, many of which remain unexplored
191 asuring the oxidation state distribution for redox sensitive radionuclides and other metal ions is ch
194 )Tc-DTPA as noninvasive imaging probes for a redox-sensitive radiotracer and a conservative flow trac
200 ryonic fibroblast cells, suggesting that the redox-sensitive regulation of mTORC1 occurs independent
202 y and conserved cysteine provides an unusual redox-sensitive regulation to an enzyme functioning in b
203 conclusion, we identified MKP-1 as a central redox-sensitive regulator of monocyte adhesion and migra
204 gh-mobility group box 1 protein (HMGB1) is a redox-sensitive regulator of the balance between autopha
205 cystathionine beta-synthase (CBS) acts as a redox-sensitive regulator that impairs CBS activity upon
208 demonstrate that caspase-1 and Prdx4 form a redox-sensitive regulatory complex via caspase-1 cystein
209 disulfide proteome, a structural group and a redox-sensitive regulatory group, with the latter having
212 effect may become critical in volatile-rich, redox sensitive rocks such as carbonate-rich lithologies
215 Empirically, sustained expression of the redox-sensitive S70pBcl2 prevents oxidative stress-induc
218 issues throughout the body and activate many redox-sensitive signal transduction and gene expression
220 itoNEET suggest that it may participate in a redox-sensitive signaling and/or in Fe-S cluster transfe
221 nfected macrophages to prevent activation of redox-sensitive signaling components that ultimately res
222 on affects skeletal muscle's performance and redox-sensitive signaling during the inflammatory and re
223 d H2O2 production resulted in disturbance of redox-sensitive signaling including Akt and MAPKs pathwa
224 induced increase in ROS production triggered redox-sensitive signaling mechanism emanating from the c
225 spectrometry-based approach to elucidate the redox-sensitive signaling network (redoxome) mediating t
227 cxcl8 gene expression, via the activation of redox-sensitive signaling pathways, and further point ou
231 This review will highlight two important redox sensitive signalling pathways that contribute to R
232 hem (reactive oxygen species, ROS) stimulate redox-sensitive signalling pathways to modify the cellul
233 duced (i) ROS generation, (ii) activation of redox-sensitive signalling pathways, and (iii) ROS stres
234 sensitivity was mediated by an extracellular redox-sensitive site, which was also highly sensitive to
235 e heads, temperatures, and concentrations of redox-sensitive species, iomeprol and 15 of its transfor
236 n that wound-induced H2O2 is detected by the redox-sensitive Src family kinase (SFK) Lyn within the r
241 induced by reactive oxygen species (ROS) on redox-sensitive targets such as zinc finger proteins pla
242 116 ppb) O(3) concentrations was examined by redox-sensitive thiol labeling, mass spectrometry, and t
243 oxidant stress, confirming that Cys405 is a redox-sensitive thiol that is necessary for ET(B)-eNOS s
245 also show that the FAD 2'-OH group acts as a redox-sensitive toggle switch that controls PutA-membran
246 e zinc center of Hsp33 appears to act as the redox-sensitive toggle that adjusts the thermostability
249 ion is consistent with crustal abundances of redox-sensitive trace elements in saponitic mudstones de
250 xidizing equivalents to mobilize sulfate and redox-sensitive trace metals from land to the oceans whi
251 rant benthic foraminiferal species, peaks in redox-sensitive trace metals, and enhanced (15)N/(14)N r
255 ed adenosine triphosphate content, and Nrf2 (redox sensitive transcription factor) up-regulation.
257 essential micronutrient that suppresses the redox-sensitive transcription factor NF-kappaB-dependent
258 Minocycline reduces ubiquitination of the redox-sensitive transcription factor Nrf2 and increases
259 demonstrate that Cu((II))ATSM activates the redox-sensitive transcription factor Nrf2 in human coron
260 unction of minocycline, which stabilizes the redox-sensitive transcription factor Nrf2, thus protecti
261 ion of MIOX induced nuclear translocation of redox-sensitive transcription factor Nrf2, which binds t
265 rythroid 2-related factor 2 (Nrf2/NFE2L2), a redox-sensitive transcription factor plays a critical ro
266 ear erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that is the key reg
267 erythroid 2 p45-related factor 2 (Nrf2) is a redox-sensitive transcription factor that regulates expr
268 tor erythroid-2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that regulates the
269 erythroid 2 p45 related factor-2 (Nrf2) is a redox-sensitive transcription factor that up-regulates a
271 ammatory processes as follows: activation of redox-sensitive transcription factors (NFkappaB) and MAP
272 mistry to determine DNA-bound potentials for redox-sensitive transcription factors because such bindi
273 the genome and facilitates the activation of redox-sensitive transcription factors globally in respon
275 ytoprotective proteins through activation of redox-sensitive transcription factors is severely attenu
276 active oxygen species-mediated activation of redox-sensitive transcription factors is the hallmark of
277 at DNA-binding sites (response elements) for redox-sensitive transcription factors may also exist in
278 sponses to contraction include activation of redox-sensitive transcription factors such as nuclear fa
279 against oxidative stress are coordinated by redox-sensitive transcription factors that transduce oxi
281 wever, does not seem to be under a classical redox-sensitive transcriptional regulation, being unresp
283 tion governing TrfA activity, wherein Spx, a redox-sensitive transcriptional regulator degraded by Cl
284 based on the authigenic accumulation of the redox-sensitive transition element molybdenum in sulphid
285 e of molecular oxygen (P = 3.4 x 10(-8)) and redox-sensitive transition metals and compounds, which i
286 aphy reveals an episode of enrichment of the redox-sensitive transition metals molybdenum and rhenium
287 phosphate oxidase and the activation of the redox-sensitive tyrosine kinase Pyk2 as essential for VE
288 Proline-rich tyrosine kinase 2 (PYK2), a redox-sensitive tyrosine kinase, directly phosphorylates
289 induces oxidation of target cysteines in the redox-sensitive tyrosine phosphatases, LMW-PTP and SHP-2
290 iple levels by Keap1, which targets Nrf2 for redox-sensitive ubiquitin-mediated degradation in the cy
293 ified SET1/MLL histone methyltransferases as redox sensitive units of the H3K4-trimethylating complex
294 xes of (232)Th and excess barium, along with redox-sensitive uranium concentrations to examine past v
296 show, using transgenic mice that expressed a redox-sensitive variant of green fluorescent protein tar
297 rylation at Ser1177 as well as expression of redox-sensitive vascular cell adhesion molecule-1 (VCAM-
299 contains an equivalent P-loop Cys, was also redox sensitive, whereas ancestral bacterial FN3K homolo
300 ealed that microvascular K(ATP) channels are redox sensitive, with oxidants increasing their activity