ライフサイエンスコーパス: reduced form of

1 lse was nearly identical to the one-electron-reduced form of 1,4,5,8-naphthalene diimide (produced in

2 ivalents), but reacts rapidly with the fully reduced form of 1-methoxy-5-methylphenazinium methylsulf

3 oxygen, suggesting activation of O(2) by the reduced form of 1.

4 s allowed the isolation of singly and doubly reduced forms of 1 a, both forming pai-complexes with ce

5 The reduced form of 17-AAG is differentiated from its oxidiz

6 ic radical that accepts an electron from the reduced form of 2,3,4,6-tetra(9H-carbazol-9-yl)-5-(1-phe

7 Mono- and doubly reduced forms of [3]TrTol were isolated as solvent-separ

8 Instead, the reduced form of 31 behaves as an electrogenerated base,

9 ies with pH and exhibits a pKa value for the reduced form of 7.5.

10 rdF does not react with O2, but it binds the reduced form of a conserved flavodoxin-like protein, Nrd

11 By integrating a reduced form of a fully coupled atmospheric model within

12 st example of crystallization of a substrate-reduced form of a Se- and Mo-containing enzyme.

13 nt differential binding between oxidized and reduced forms of a 5-deazariboflavin derivative that is

14 f the binding constants for the oxidized and reduced forms of a bound species, binding free energy (d

15 entation sites, respectively, for native and reduced forms of a disease-associated SOD1 variant.

16 Switching in situ between the oxidized and reduced forms of a metal complex resulted in a change in

17 ological evidence that the conversion of the reduced form of AGT to its more active oxidized form is

18 Both one- and two-electron reduced forms of all zinc complexes studied have strong

19 This reduced form of alpha-ketoisocaproic acid was found to s

20 Dihydrolipoic acid (the reduced form of alpha-lipoic acid), which contains free

21 the interconversion between the oxidized and reduced forms of androgens and estrogens at the 17 posit

22 SVCT2 transports the reduced form of ascorbate into neurons and microglia, ho

23 The emergence of a reduced form of astatine, At(2), at higher radiation dos

24 At(2) was identified as a reduced form of astatine, presumably astatide, which cou

25 We demonstrate that the reduced form of Bacillus subtilis OhrR binds cooperative

26 Partially and fully reduced forms of benzo-fused eight- to ten-membered nitr

27 A new method for the synthesis of the reduced form of beta-nicotinamide [U-14C]adenine dinucle

28 ces to a greater iron-copper distance in the reduced form of bo(3) compared to that of ba(3).

29 Reduced forms of both AphB and OhrR directly bind to the

30 The reduced forms of both pyridine nucleotides are fluoresce

31 The disulfide-reduced form of bovine ribonuclease A, with the Cys thio

32 5 inhibits fatty acid synthesis; (b) C273, a reduced form of C75, is unable to inhibit fatty acid syn

33 ditions of the aromatic ketone reduction, or reduced form of Celastrol, had significantly decreased t

34 es of the protein agree on a predominance of reduced form of CISD3 in the cells.

35 Tase, ASNase, and ADI), NADPH/NADP(+) and/or reduced form of coenzyme Q (CoQH(2))/CoQ redox potential

36 The reduced form of CoQ is an antioxidant, which protects ag

37 Isolation of the reduced form of Cp*(3)CoMo(2)S(4) and subsequent reactiv

38 was also carried out, demonstrating that the reduced forms of CPR and CYP2C9 interact differently wit

39 Here we present the NMR structure of the reduced form of Cr-TRP16, along with its regulation of N

40 e mixed-valence form and 2.52 A in the fully reduced form of CuA.

41 Surprisingly, the reduced forms of cyclic nitroxides, cyclic hydroxylamine

42 be required to promote the formation of the reduced form of Cys 266, which is otherwise unreactive.

43 t with a square scheme in which oxidized and reduced forms of cyt P450s each participate in rapid con

44 The reduced form of cytochrome c2 strongly binds to reduced

45 tron reduction at -0.09 V vs SCE (MeCN), and reduced forms of DCNT have yet to be isolated and charac

46 We conclude that both oxidized and reduced forms of dCRY are capable of photosignaling.

47 y than its reduced form and the oxidized and reduced forms of Defr1 Y5C.

48 he reduced form of the wild-type enzyme, the reduced form of DeltaP34 Trx has disulfide isomerization

49 stal structures of the one- and two-electron reduced forms of diaryl-o-carboranes are disclosed to ga

50 In contrast, the reduced forms of disulfiram and cystamine, diethyl dithi

51 In addition, two reduced forms of DMSO reductase, prepared either anaerob

52 n and reduction are effected by oxidized and reduced forms of E. coli thioredoxin.

53 se data support the hypothesis that bats use reduced forms of echolocation and fly in silence to avoi

54 tial, consistent with oxygen reacting with a reduced form of enzyme before release of the carbonyl pr

55 te indicated that the catalytically relevant reduced form of enzyme is an anionic flavin semiquinone,

56 studies are now extended to the oxidized and reduced forms of ferredoxin I from spinach.

57 ng solutions (pH 5.0, 6.0, 7.0) containing a reduced form of flavin mononucleotide (FMNH2, 100 muM),

58 e ligand, only the oxidized and two-electron-reduced forms of FMN are detected.

59 that this is enabled due to the oxidized and reduced forms of FMN-Na being stabilized by resonance st

60 ized, one-electron-reduced, and two-electron-reduced forms of FTR.

61 othesis regarding the unknown peak to be the reduced form of furaneol(R).

62 m effects, including decreased levels of the reduced form of glutathione (GSH) and elevated oxidative

63 al is not only a well-known precursor of the reduced form of glutathione (GSH), but also is an scaven

64 and antioxidants N-acetylcysteine (NAC) and reduced form of glutathione (GSH).

65 ect was mimicked by external addition of the reduced form of glutathione ethyl ester.

66 es in plasma, together with decreases in the reduced form of glutathione in erythrocytes.

67 f these protein groups was achieved with the reduced form of glutathione or glutaredoxin, a protein k

68 mpounds by catalysing the conjugation of the reduced form of glutathione to the substrate.

69 Glutathione reductase, which regenerates the reduced form of glutathione, represents one such anti-ox

70 ly reversed by dithiothreitol but not by the reduced form of glutathione, suggesting that the disulfi

71 X, the antioxidant N-acetylcysteine, and the reduced form of glutathione.

72 The reduced form of graphene oxide (GO) is an attractive alt

73 ove the oxygen functional groups so that the reduced form of graphene oxide (GO; reduced form: rGO) r

74 The active, reduced form of GSH is rapidly degraded thus making it d

75 tructure, the NMR solution structure for the reduced form of hDim1(1)(-)(128) presented here, along w

76 hat the R391A mutation might destabilize the reduced form of heme b(558).

77 Overall, our results show that the reduced form of HMGB1 coordinates tissue regeneration an

78 f the carmustine type inhibit only the NADPH reduced form of human thioredoxin reductase.

79 131)-Arg(153) peptides from the oxidized and reduced forms of human RNase H1 in the presence and abse

80 BSO (10 micromol/L) depleted the reduced form of intracellular glutathione without induci

81 Fully and partially reduced forms of isolated bovine cytochrome c oxidase un

82 or of vitamin K is strictly dependent on the reduced form of its naphthoquinone ring.

83 The reduced form of JAK2 is the most active form, and the ox

84 he structural similarity between SAc and the reduced form of lipoic acid, a step which is similar to

85 tructures were obtained for the oxidized and reduced forms of M98A and M98Q amicyanins at atomic reso

86 ociation rate constant for NO binding to the reduced form of MPO, MPO-Fe(II), was over an order of ma

87 The biosensor detects reduced forms of MSMA and roxarsone and offers a practic

88 The interaction between Pck and the reduced form of mycobacterial thioredoxin, gene expressi

89 t of a paramagnetic Fe-S compound that binds reduced forms of N2 involved Fe complexes stabilized by

90 Both the oxidized and reduced forms of Na(+)-NQR exhibit a radical EPR signal.

91 icles (NPs) loaded with either NAD(+) or the reduced form of NAD(+) (NADH), hereafter NAD(H)-loaded N

92 RoDH-E2, with cytoplasmic phosphorylated and reduced forms of NAD-dependent retinol dehydrogenase act

93 cycle impairment, whereas metabolites in the reduced form of NADH-dependent lysine degradation pathwa

94 NADPH/NADP(+) (the reduced form of NADP(+)/nicotinamide adenine dinucleotid

95 ion for relief from inhibition by NADPH (the reduced form of NADP) expected of an adaptive landscape

96 6-diphosphate (FDP), 1.5-fold by oxidized or reduced forms of NADP, and 10-fold by HPr-P (Ser-46).

97 n of FDH and its complexes with oxidized and reduced forms of NADP.

98 drogenase (G6PD) regulates production of the reduced form of NADPH through the pentose phosphate path

99 ed the X-ray structures of oxidized and NADH-reduced forms of naturally folded recombinant murine AIF

100 hysiological temperature of 37 degrees C the reduced form of nicked BoNT/E adopts a dynamically flexi

101 icotinamide adenine dinucleotide(+) (NAD(+))/reduced form of nicotinamide adenine dinucleotid (NADH)

102 ponse to nicotinamide coenzymes, such as the reduced form of nicotinamide adenine dinucleotide (NADH)

103 lar oxidoreductase that is stimulated by the reduced form of nicotinamide adenine dinucleotide (NADH)

104 widely used to functionally characterize the reduced form of nicotinamide adenine dinucleotide and ni

105 imiting rearrangements of the FAD and NADPH (reduced form of nicotinamide adenine dinucleotide phosph

106 y underlie conidial susceptibility to NADPH (reduced form of nicotinamide adenine dinucleotide phosph

107 cing systems in vascular wall include NADPH (reduced form of nicotinamide adenine dinucleotide phosph

108 adenine dinucleotide phosphate (NADP(+)) to reduced form of nicotinamide adenine dinucleotide phosph

109 ule production, increasing expression of the reduced form of nicotinamide adenine dinucleotide phosph

110 antimicrobial mechanisms such as the NADPH (reduced form of nicotinamide adenine dinucleotide phosph

111 al and malondialdehyde as substrates and the reduced form of nicotinamide adenine dinucleotide phosph

112 n the presence and absence of cofactors (the reduced form of nicotinamide adenine dinucleotide phosph

113 li initiates synthesis of RNA with NADH (the reduced form of nicotinamide adenine dinucleotide) and F

114 logically important metabolites, such as the reduced form of nicotinamide adenine dinucleotide.

115 ment can simultaneously measure oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD(

116 dinucleotide (NAD(+) and NADH), oxidized and reduced forms of nicotinamide adenine dinucleotide phosp

117 e in this reaction, with NADH and NADPH (the reduced forms of nicotinamide adenine nucleotide and nic

118 ormation on both types of Cu centres for the reduced form of NiR from Alcaligenes xylosoxidans (AxNiR

119 A formally reduced form of nitrenium D-cyclic triazanes E-are intri

120 Nitroxyl anion (HNONO(-)), the one-electron reduced form of nitric oxide (NO), induces positive card

121 etection of nitroxyl (HNO), the one-electron reduced form of nitric oxide (NO), is reported.

122 Nitroxyl (HNO), the one-electron-reduced form of nitric oxide, enhances cardiac function

123 Nitroxyl (HNO/NO(-)), the reduced form of nitric oxide, has gained attention based

124 f nitroxyl (HNO), the transient one-electron reduced form of nitric oxide, is a significant challenge

125 ides evidence for nitroxyl, the one-electron reduced form of nitric oxide.

126 ide, evidence for nitroxyl, the one-electron-reduced form of nitric oxide.

127 Reduced forms of nitrogen (NH(x) = ammonia [NH(3)] + amm

128 onary biology of (a) elemental nitrogen; (b) reduced forms of nitrogen such as amines, ammonia, and h

129 Nitroxyl, HNO/NO(-), the one-electron reduced form of NO, is suggested to take part in distinc

130 e present here the crystal structures of the reduced form of NTR and its complexes with the inhibitor

131 We previously reported that the reduced form of OxyR is sufficient for repression of tra

132 epressed by OxyR(C199S), which resembles the reduced form of OxyR.

133 upporting the proposal that the oxidized and reduced forms of OxyR interact differently with their ta

134 nantly to the increased concentration of the reduced form of P680 ([P+] is low).

135 tide is initially unfolded by binding to the reduced form of PDI.

136 To understand how the reduced form of Pdx is stabilized and how reduction of t

137 -2,2'-bitriazine, [TCBT]*-, the one-electron reduced form of planar (D(2h)) TCBT, which is also struc

138 urther oxidation decreased the levels of the reduced forms of polysulfide and the antioxidative effec

139 titanium dioxide, while potassium bromide (a reduced form of potassium bromate) was detected in all s

140 The reduced form of Prussian blue, called Prussian white, is

141 e presence of the sulfinic form (but not the reduced form) of PrxI induces the conserved cysteine of

142 at recognize epitopes common to oxidized and reduced forms of PTP1B.

143 ized forms of Pu sorb less to sediments than reduced forms of Pu.

144 nd structural properties of the oxidized and reduced forms of Pyrococcus furiosus superoxide reductas

145 Copper also binds the four-electron-reduced form of QSOX with a visible spectrum suggestive

146 The reduced forms of quinone, tert-butylhydroquinone, and 5-

147 Most recently, the reduced form of (R)-lipoic acid, (R)-dihydrolipoic acid,

148 y-state voltammograms with both oxidized and reduced forms of redox species initially present in solu

149 Although responses to the reduced forms of redox-active metals, such as Mn(II) and

150 Thus, the unfolded reduced forms of RNase A are not statistical coils with

151 d increase in the propensity of the unfolded reduced forms of RNase A to form the native set of disul

152 angle x-ray scattering showed that the fully reduced form of Rv2466c adopts a "closed" compact confor

153 Strikingly, a new crystal structure of the reduced form of Rv2466c revealed the binding of a C-term

154 Despite the reduced forms of Se being oxidized, very little Se was r

155 The observation of the reduced forms of several metal-containing proteins using

156 The structures of the oxidized and reduced forms of SOR suggest a mechanism by which supero

157 xylated by a P450 monooxygenase to yield the reduced form of sorgoleone.

158 ster ligands C45 and C64 in the oxidized and reduced forms of T4MOC.

159 The stability of the one-electron reduced form of TCAQ renders it the acceptor of choice.

160 ere, we report the solution structure of the reduced form of the 98-amino acid Fd domain determined b

161 clearly distinguished the oxidized from the reduced form of the binuclear cluster.

162 atom of PQQ in that study represents the C-5-reduced form of the cofactor and lends support for a hyd

163 n in yeast and that inadequate levels of the reduced form of the cofactor can produce lethality.

164 modified ligand diminish the ability of the reduced form of the complex to serve as a nucleophile bu

165 ical to the Cu...Cu distance observed in the reduced form of the Cu(A) site of thiolate-bridged cytoc

166 we determined the solution structure of the reduced form of the dominant negative human hDim1 (hDim1

167 In the reduced form of the double mutant, an N/O ligand was app

168 undertake a thorough characterization of the reduced form of the enzyme and the determination of the

169 epresents the formation of the four-electron reduced form of the enzyme, EH(4).

170 and the bend increases (25 degrees ) in the reduced form of the enzyme, roughly the conformation pre

171 exhibited cleavage rates comparable with the reduced form of the enzyme, suggesting that the cysteine

172 e heteroduplex substrate comparable with the reduced form of the enzyme.

173 lex requires reaction of O(2)(*)(-) with the reduced form of the enzyme.

174 rential binding of NADP+ to the oxidized and reduced form of the enzyme.

175 neutral FAD radical are also observed in the reduced form of the enzyme.

176 -SSG with GRX led to the regeneration of the reduced form of the enzyme.

177 s a characteristic 1405 cm(-)(1) band of the reduced form of the FMN cofactor.

178 , known clinically as leucovorin, which is a reduced form of the folic acid present in DMEM.

179 A stable reduced form of the ICL has applications in understandin

180 Using a reduced form of the Kuramoto model, we analyse how a pat

181 The solution structure of the reduced form of the MAL TIR domain, determined by NMR sp

182 The reduced form of the mediator is markedly more reactive t

183 K, which was also seen in simulations of the reduced form of the mesophilic Clostridium pasteurianum

184 m bis(hydromethanesulfonate; LMTM), a stable reduced form of the methylthioninium moiety, acts as a s

185 CO binds to the reduced form of the mutants, indicating that it is able

186 Proxy(OH) is a reduced form of the OH steady-state equation representin

187 equilibrium between two conformations of the reduced form of the oxidase.

188 here backbonding from uranium gives a highly reduced form of the P-C-O unit that is perhaps best desc

189 tion of beta-RFA-P and the accumulation of a reduced form of the proposed cyclohexadienimine reaction

190 t FMOs exist in the cell as a complex with a reduced form of the prosthetic group and NADPH cofactor,

191 The reduced form of the protein exhibited an EPR spectrum ch

192 he folding reactions, we found the disulfide-reduced form of the protein that exposes the C-terminal

193 6, was identified that existed in an already reduced form of the quinone.

194 y and folding of the protein, we studied the reduced form of the recombinant human PrP as well as the

195 ligand was apparent that was not seen in the reduced form of the T1D protein.

196 es that are involved in the transport of the reduced form of the tetrazolium dye 3-(4,5-dimethylthiaz

197 The reduced form of the thromboxane A(2) receptor experience

198 and proteomic data proved the presence of a reduced form of the translocon of inner membrane, they f

199 e oxidized enzyme reacts with ubiquinol (the reduced form of the usual electron acceptor) in a proces

200 In contrast to the reduced form of the wild-type enzyme, the reduced form o

201 al spectroscopy (NRVS) to study oxidized and reduced forms of the [4Fe-4S] cluster in the D14C varian

202 isms involving either one- or three-electron reduced forms of the A cluster as immediate precursors t

203 .86 and gav = 1.87 signals characteristic of reduced forms of the active site (center C) of wild-type

204 Reduced forms of the C56S and C60S variants of the thior

205 the variants are similar, EPR spectra of the reduced forms of the cluster show small differences in s

206 owing incubation of NBD-Cl with oxidized and reduced forms of the denatured peroxidase, indicating a

207 Titrations of the reduced forms of the domains with artificial electron ac

208 s performed on the succinate- and dithionite-reduced forms of the enzyme demonstrated that the 4Fe-4S

209 chroism spectral studies of the oxidized and reduced forms of the enzyme suggest the Fe centers to be

210 9-nortestosterone binds to both oxidized and reduced forms of the enzyme with dissociation constants

211 ide and azide were added to the oxidized and reduced forms of the enzyme, and Mn(II) CW-EPR and ESEEM

212 of CuB, in both the fully oxidized and fully reduced forms of the enzyme, has been examined by Cu XAS

213 es suggest that it is the immature disulfide-reduced forms of the familial ALS mutant SOD1 proteins t

214 arison of the structures of the oxidized and reduced forms of the native enzyme shows that the princi

215 of the 7-nitrobenzoxadiazole lead, carrying reduced forms of the nitro group and/or oxidized forms o

216 The oxygenated and reduced forms of the prosthetic group help stabilize int

217 The crystal structures of the oxidized and reduced forms of the protein reveal that the copper site

218 nces in UDP binding between the oxidized and reduced forms of the protein which most likely explain t

219 te binds to the inactive oxidized and active reduced forms of the protein with similar affinities.

220 In the semiquinone and reduced forms of the protein, the Gly57-Asp58 peptide ad

221 re separated by 6 A in both the oxidized and reduced forms of the protein.

222 ce mass spectrometry allows the oxidized and reduced forms of the proteins to be distinguished.

223 quantum chemical models of the oxidized and reduced forms of the proteins, based upon both isolated

224 Resonance Raman data of the oxidized and reduced forms of the R481L mutant indicate that the muta

225 The reduced forms of the redox cofactors, NAD(H) and NADP(H)

226 nd by the concentrations of the oxidized and reduced forms of the redox couple.

227 eme group in oxidized, reduced, and CO-bound reduced forms of the Rhodospirillum rubrum CO oxidation

228 ion of the mixed-valence (i.e., two-electron reduced) form of the enzyme with dioxygen.

229 ligand charge-transfer excited state and the reduced form of these compounds do not inject electrons

230 -N(3)(-) complexes in oxidized and substrate-reduced forms of these enzymes.

231 In contrast, reduced forms of these in vivo models led to discrepanci

232 Reaction of oxygen with reduced forms of these modified enzymes in the absence o

233 ing cells in the root meristem, in which the reduced forms of these two species are favored.

234 In addition, only the reduced form of thioredoxin activated NF-kappaB, whereas

235 to compare backbone dynamics of oxidized and reduced forms of this 414-residue metalloenzyme via hydr

236 2466c allowing the release of the activated, reduced form of TP053.

237 o a rate-limiting electron transfer from the reduced form of TPQ (p-aminohydroquinone form) to dioxyg

238 copper-associated water molecule to form the reduced form of TPQ (TPQ(red)), followed by facile oxida

239 The reduced form of Trx suppresses the serum-free-induced hy

240 The reoxidations of two chemically distinct reduced forms of TTQ were studied, a quinol (O-quinol) g

241 he ET reactions from two chemically distinct reduced forms of TTQ were studied: an O-quinol form that

242 chain, and recent evidence suggests that the reduced form of ubiquinone (QH2) may play a second role

243 Recent evidence suggests that the reduced form of ubiquinone (ubiquinol) may also function

244 Inducer binding for both oxidized and reduced forms of V52C was comparable to wild-type lac re

245 lotoxin did not affect cytotoxicity, and the reduced form of wild-type CdtA exhibited a statistically

246 VTMCD studies show that the CO-bound reduced forms of wild-type, H77Y, and C75S contain low-s

247 he low-temperature photoproducts of CO-bound reduced forms of wild-type, H77Y, and C75S CooA.

248 resolved XPS measurements suggest that these reduced forms of Y and Zr exist only within the first fe