ライフサイエンスコーパス: redundant

1 damental distinction between 'parallel' and 'redundant'.

2 driven proliferation pathways 'parallel' or 'redundant'?

3 Thus, are they 'redundant'?

4 , the three Cag ATPases are not functionally redundant.

5 s making the 'cryptic' addition to 'species' redundant.

6 circularly permuted and about 13% terminally redundant.

7 CDK19, which are presumed to be functionally redundant.

8 yze Nva-tRNAs even when editing of Nva seems redundant.

9 ither of those scientific positions would be redundant.

10 t interestingly, LC3 proteins appeared to be redundant.

11 rtex, a response that may seem unnecessarily redundant.

12 ng a neural code thought to be predominantly redundant.

13 s of the gene rendering each individual copy redundant.

14 ilar activities and are largely functionally redundant.

15 nformation that is complementary rather than redundant.

16 ways are parallel; those of Ras isoforms are redundant.

17 s appear strongly functionally clustered and redundant.

18 1/NOD2 nodosome signaling to be individually redundant.

19 Although these pathways were thought to be redundant, a DeltalipL mutant, in which the endogenous l

20 al trait is strain specific yet functionally redundant across phylogenetic lineages of the microbiota

21 e found evidence for essential and partially redundant actions of retina-derived (paracrine) and astr

22 gene functions can be probed effectively and redundant activities of genes can be uncovered when two

23 his risk may be mitigated by the use of dual redundant, albeit functionally unrelated, lethality syst

24 ow that PtmO3 and PtmO6 are two functionally redundant alpha-ketoglutarate-dependent dioxygenases tha

25 intervals are used, then the p-value may be redundant and can be omitted from reports.

26 t to provide a comprehensive analysis of the redundant and distinct roles of IL-4 and IL-13 in type 2

27 rases, DNMT3A and DNMT3B, which exhibit both redundant and distinctive methylation activities.

28 DASE9 (PRX9) and PRX40, that are genetically redundant and essential for proper anther and pollen dev

29 eature selection procedure to further remove redundant and irrelevant features in an effort to improv

30 After removing redundant and non-reproducible features, optimal linear

31 After removing redundant and non-reproducible radiomics features, backw

32 hat observed in IL-36R(-/-) mice, indicating redundant and overlapping roles for these cytokines in e

33 r data propose that influenza A virus uses a redundant and plastic network of RNA-RNA and potentially

34 influenza A virus genome is controlled by a redundant and plastic network of RNA/protein interaction

35 serine/threonine kinases that are partially redundant and regulate multiple pathways important for c

36 We show that these three TFs have both redundant and specific functions in ependymal cells.

37 ctions through the degradation of misfolded, redundant, and damaged proteins.

38 tia suggested that the two datasets were not redundant, and it is proposed that ICP-MS data is the mo

39 d that C2 and C10 are partially functionally redundant, and some but not all disease-causing mutation

40 ediated immunity, knowledge of the specific, redundant, and synergistic functions of helper RNLs is l

41 romes (NIS), nonbacterial infections, use of redundant antimicrobials, and continuation of empirical

42 ation and visual perception convey partially redundant appearance information.

43 of colitogenic CD4(+) T cells, which becomes redundant as colitis progresses.

44 ancestries are dependent and can provide non-redundant association information.

45 e connectivity level could be related to the redundant associations observed genome-wide between gene

46 oolkit to cluster, evaluate, and extract non-redundant associations of Gene Ontology-based functions.

47 Screen analysis confirmed non-redundant ATL functions and identified a specific role f

48 1 double-knockout and SAA3 knockout mice had redundant attenuation of the extent of periapical lesion

49 ligands and receptors are both specific and redundant: BAFFR binds BAFF, whereas BCMA and TACI bind

50 ckaging; furthermore, there are functionally redundant binding sites in viral RNA.

51 P-1 family of transcription factors play non-redundant biological roles despite recognizing the same

52 These mice reveal the redundant but critical role of SMAD8 in hepcidin and iro

53 tivity, whereas SPTLC2 and SPTLC3 are partly redundant but differ in their enzymatic properties.

54 ns (ANPs) ANP32A and ANP32B are functionally redundant but essential host factors for mammalian-adapt

55 rine embryonic fibroblasts in vitro, and the redundant but essential roles of both mitochondrial anti

56 that GcorInR1 and GcorInR2 are functionally redundant but that the latter is partially specialized f

57 ides (XMAn-v1) that complemented a minimally redundant, canonical database of Homo sapiens proteins.

58 tworks, the components in the network have a redundant capacity against the load, such as power grids

59 considering overloaded edges to describe the redundant capacity for edges and capture the interaction

60 vering the importance of the other seemingly redundant cell wall enzymes.

61 ntitative leptin expression is controlled by redundant cis elements and trans factors interacting wit

62 It contains redundant classical cis-acting signals necessary for the

63 maintained at Miami, FL contains > 1,200 non-redundant clones of different species and genera within

64 Redundant coding is widely believed to reflect a design

65 rotein expression in cocultures but acquired redundant compensatory signals enabling anchorage indepe

66 al depletion has been challenging due to the redundant complexity of its biosynthesis and the lack of

67 he transcription factor BMAL1/ARNTL is a non-redundant component of the clock pathway that regulates

68 6B and TNRC6C, as functionally important but redundant components of the miR-122/Ago2 host factor com

69 These redundant connections could maintain transmission of vol

70 Next, the impact of redundant constraints, sensitivity to constraint orderin

71 regulatory partner, allowing for dynamic and redundant control of p53-mediated transcription.

72 Those redundant copies are functional and are undergoing stron

73 al system suffered from low yields, deleting redundant copies of tRNA(fMet) from the genome afforded

74 Faith's Phylogenetic Diversity and non-redundant covariate analyses reveal that the serum 1,25(

75 nce bias as well as near-complete and highly-redundant coverage.

76 Compared with conventional methods using redundant cross-linking reactions, our method is simpler

77 Bacillus subtilis encodes two functionally redundant D,L-endopeptidases (CwlO and LytE) that cleave

78 e from a set of noisy optical inputs without redundant data storage, processing, and communications a

79 conclude that KWL1 and KWL1-b are part of a redundant defense system that tissue-specifically target

80 on, and diversification of these potentially redundant defenses across this genus.

81 dancers demonstrated greater utilization of redundant degrees of freedom (DoFs) supported by the gre

82 tral nervous system's ability to utilize the redundant DoFs in the whole-body system.

83 ammation initiation, also functions as a non-redundant downstream effector in inflammation clearance.

84 op a more dynamic and flexible model for how redundant, dynamic, and competing protein interactions c

85 trade-off governing their formation: adding redundant edges to supply networks is costly, yet benefi

86 binding sites and identified synergistic and redundant effects.

87 Moreover, genes with redundant enhancer domains are depleted of cis-acting ge

88 Deleting a redundant enhancer from the svb locus led to reduced tri

89 Shadow enhancers, groups of seemingly redundant enhancers, are found in a wide range of organi

90 human genome are established by an array of redundant enhancers.

91 sites and the gene promoter, suggesting non-redundant enhancers.

92 In total, 154,586 non-redundant enset microsatellite markers (EMM) were identi

93 our findings reveal previously thought to be redundant enzymes are instead specialized for distinct e

94 o indicate that FASs with multiple partially redundant enzymes enable tighter (i.e., more independent

95 tic rationale for the inclusion of partially redundant enzymes in fatty acid pathways and supplies a

96 the catalytic capabilities of two partially redundant enzymes).

97 le protein complexes as well as functionally redundant enzymes.

98 H-we discovered a subset of these so-called 'redundant' enzymes in Escherichia coli are required for

99 he relevance of MIF's partially functionally redundant family member, D-dopachrome tautomerase (D-DT)

100 e power to the neural network, we argue that redundant features could rather clutter the scenario and

101 to determine the most informative and least redundant features necessary for call classification.

102 f Fgf8 expression suggests that functionally redundant FGF ligands may contribute to vestibular hair

103 We conclude that Tfr1 is redundant for basal hepatocellular iron supply but essen

104 Moreover, NOS2 appeared to be redundant for control of other pathogens in this patient

105 ociated mucosal inflammation is important or redundant for effective induction of immunity is, howeve

106 Here, we show that VAPA and VAPB are redundant for HCV infection and that dimerization is not

107 We demonstrate that WAVE1 and WAVE2 are redundant for lamellipodia formation and motility.

108 sk of severe disease and are nonredundant or redundant for protection against SARS-CoV-2.

109 We identified mTOR to be redundant for sustaining T-bet expression in activated T

110 hermore, the DNA binding activity of DnaD is redundant for this filament remodelling.

111 produced from mature tRNA sequences and are redundant fragments.

112 NIPSNAP1 and NIPSNAP2 have a redundant function in mitophagy and are predominantly ex

113 oci, only RFX2 and RFX3 play a prominent and redundant function in the control of motile ciliogenesis

114 ocot maize, Kranz patterning is regulated by redundant function of SCARECROW 1 (ZmSCR1) and a previou

115 al deletion, and given previous data showing redundant function of Smad2 and Smad3, a double-conditio

116 These findings reveal a redundant function of XBP1s and ATF6 as activators of th

117 , especially when there are many toxins with redundant function.

118 s from different gene families or genes with redundant functions in the same gene family can be exami

119 r, a clear understanding of the specific and redundant functions of different RFX factors in ciliated

120 typical E2F family members, the specific and redundant functions of E2F proteins, how misexpression o

121 ion and mucus production, thus demonstrating redundant functions of these cytokines.

122 In conclusion, partially redundant functions of UNC-87 and CLIK-1 in ovulation ar

123 numerous receptors, and appear to have many redundant functions, as demonstrated by studies of knock

124 e intriguing proteins to determine their non-redundant functions.

125 and whether the different IP3R isoforms have redundant functions.

126 and biochemical interactions, serve largely redundant functions.

127 that the 3 bestrophin-like proteins may have redundant functions.

128 appear to provide complementary rather than redundant functions.

129 We identified 1305 non-redundant fusion events from 388 transcriptomes represen

130 e assemble a comprehensive human vaginal non-redundant gene catalog (VIRGO) that includes 0.95 millio

131 ranscription patterns and sequences of those redundant gene copies between resynthesized allopolyploi

132 apabilities of CRISPR screens to investigate redundant gene function in highly duplicated plant genom

133 n efficiency and determines relevant and non-redundant gene markers from three cancer gene expression

134 of CMVMC, a reduced set of relevant and non-redundant genes are found for each chosen data set.

135 the presence of a large number of irrelevant/redundant genes in expression data makes a sample classi

136 talog (VIRGO) that includes 0.95 million non-redundant genes.

137 e Tara Oceans data, we obtain 97 million non-redundant genes.

138 However, transcription of these 'coactivator-redundant' genes is strongly affected by rapid depletion

139 encephaly in mice is actively maintained via redundant genetic regulation of dorsal midline developme

140 In addition, we discover ~60 Mb of non-redundant genome content missing in the reference genome

141 multiple individuals and reconstruct 790 non-redundant genomes, 43 of which resolve to TM7, a member

142 s of GO terms, minimize biases introduced by redundant GO terms in data interpretation, and batch pro

143 neurodegeneration, suggesting that these non-redundant GTPases function in the same pathway to mitiga

144 ght into functional specificity of seemingly redundant Hsp90s, and the evolution of eukaryotic Hsp90

145 in the SAC because both phosphatases become redundant if PLK1 is inhibited or BUB-PLK1 interaction i

146 e same downstream protein families, they are redundant; if evolutionary-independent, they are paralle

147 ical inhibition of necroptosis was partially redundant, implying interlinked roles of these two pathw

148 Strikingly, DC expression of OX40L is redundant in a chronic intestinal Th1 response and expre

149 with better attention switching skills were redundant in efficient ways, demonstrating that the pres

150 The two isoforms are largely redundant in function and hence are often referred to ge

151 While Arabidopsis Peps appear largely redundant in function, previous work examining Pep-induc

152 ms of 2-OGDH E1 subunit are not functionally redundant in plant growth and development of A. thaliana

153 t the two E(1) isoforms are not functionally redundant in terms of plant growth in A. thaliana.

154 the assumption that older male elephants are redundant in the population and raise concerns over the

155 we show that EZH1 and EZH2 are functionally redundant in the slowly proliferating MPNST precursors.

156 ation domains (ADs), with AD1 and AD2 having redundant, independent, and cooperative functions in a c

157 redundant, or do they modulate their use of redundant information to facilitate communication?

158 sory systems must reduce the transmission of redundant information to function efficiently.

159 y, that this algorithm is able to filter out redundant information, enhance discrimination between od

160 not only increase the cost but also generate redundant information.

161 troponin T provide complementary rather than redundant information.

162 rge onto each postsynaptic muscle fiber, all redundant inputs are removed during early postnatal deve

163 upports included calm clinician behavior and redundant intraoperative resourcing.

164 ts of the TORC2 network identified a pair of redundant kinase paralogues called Ark1 and Prk1.

165 whereas re-import is mediated by Kap122 plus redundant, kinetically less efficient import pathways.

166 ehensive pipeline is needed to produce a non-redundant library of TEs for species lacking this resour

167 Overcoming the challenge posed by redundant ligands requires a deeper understanding of con

168 d reinforce conserved genome architecture as redundant loop anchors.

169 e ADR1 and NRG1 families act in an unequally redundant manner in basal resistance, effector-triggered

170 ecules RSPO1 and RSPO3 act in a functionally redundant manner to permit WNT/beta-catenin signalling a

171 role in inhibiting end resection, acts in a redundant manner with BRCA1 to load PALB2 onto damaged D

172 ion tolerance in seeds in a gene-specific or redundant manner.

173 al analyses, we have identified functionally-redundant MAPKK-kinases (M3Ks) that are necessary for ac

174 e selection and identifying relevant and non-redundant marker genes from high dimensional gene expres

175 ed with the two assays; however, the rate of redundant markers was dramatically reduced with the BARC

176 After filtering low quality and redundant markers, GWAS was conducted using 24,977 SNPs

177 engages the acidic patch, and we elucidate a redundant mechanism of acidic patch binding by nuclear p

178 They also suggest a redundant mechanism of recruitment of GBF1 to the replic

179 poiesis was not rejuvenated, indicating that redundant mechanisms inhibit that process.

180 uality control, neurons likely have multiple redundant mechanisms to ensure their long-term survival.

181 biological reconfiguration via multiple, non-redundant mechanisms.

182 Regulatory T cells (Tregs) are non-redundant mediators of immune tolerance that are critica

183 an, via three interconnected and potentially redundant metabolic pathways.

184 logy, suggesting that other complementary or redundant mitochondrial quality control pathways may exi

185 t, in Arabidopsis, an extremely functionally redundant mitogen-activated protein kinase (MAPK) cascad

186 t version of PRISMOID encompasses 17 145 non-redundant modification sites on 3919 related protein 3D

187 Tested on 510 non-redundant MPs, our server predicts correct folds for ~29

188 The database comprises 2 539 031 non-redundant mutated entries from 17 599 proteins, of which

189 This study reveals the complex and redundant nature of the plant transcription regulatory n

190 We show how adding apparently redundant neurons and connections to a network can make

191 tome was annotated with BLASTx using the non-redundant (nr) protein database, and Gene Ontology (GO)

192 tunately, most public databases, such as non-redundant (NR), rely on user input and do not have metho

193 We first identified redundant nuclear copies involved in those complexes.

194 TP-0903, an AXL kinase inhibitor, influences redundant oncogenic pathways in metastatic lung cancer c

195 s the striatum through these two pathways is redundant or complementary.

196 ctive facial characteristics and suppressing redundant or irrelevant responses across the population.

197 owever, there are also product ions that are redundant or uninformative, resulting in more congested

198 n follows: Are older adults indiscriminately redundant, or do they modulate their use of redundant in

199 whether they all localize to the matrix, are redundant, or have different roles is unresolved.

200 Yet, the hierarchical, redundant, or independent cooperation of each active zon

201 ed GO terms are often too large and contains redundant overlapping GO terms hindering informative fun

202 ervations strongly suggest that functionally redundant paralogs represent a targetable set of genetic

203 eutics include: (1) lack of consideration of redundant pathways controlling ATP and adenosine levels;

204 gosome formation, suggesting independent and redundant pathways for actin-mediated autophagy in plant

205 We suggest that either multiple redundant pathways function in T-DNA integration, and/or

206 at multiple integrative regulatory and often redundant pathways have evolved to detect and respond to

207 that E2 action through astrocytes activates redundant pathways promoting BM.

208 localization to dendritic spines, supporting redundant pathways that control tau mislocalization to s

209 Higher eukaryotes have evolved elegant and redundant pathways to protect their genomes from both ge

210 ific, chromatin-accessible, and parallel (or redundant) pathways to thwart the expected emergence of

211 ejection, revision, and resubmission causing redundant peer review.

212 activity of the E3 SUMO ligase NSE2, as non-redundant players that control the timing of the Topo2a-

213 Here, we show that two redundant PP2C phosphatases, Ptc2 and Ptc3, regulate mac

214 ise the question whether breast surgery is a redundant procedure.

215 for these extra genes in both GenBank's non-redundant protein database and all of the metagenomes in

216 The non-redundant protein database constructed from the proteins

217 R-enriched library peptides to probe the non-redundant protein database, bacterial peptides that elic

218 LNT2-CDG suggest that there are multiple non-redundant protein substrates of GALNT2 in various tissue

219 When the accumulation of redundant proteins exceed degradation, undesirable signa

220 Currently, PhaSepDB includes 2914 non-redundant proteins localized in different organelles cur

221 ce of genes encoding apparently functionally redundant proteins.

222 scale benchmark experiments based on 614 non-redundant proteins.

223 differential, partially overlapping but non-redundant regulation of anti-tumor immunity.

224 ory and show that Akt2 is a critical and non-redundant regulator of mTOR activity in brain.

225 This connectivity suppressed redundant responses and was necessary and sufficient to

226 at are repeated within short periods lead to redundant results at additional costs.

227 We define two separable and redundant RhoGEF/Pebble-dependent inputs into Sticky rec

228 We confirm an essential and non-redundant role for ADAM17 in TCR-induced proteolysis of

229 Thus, our findings establish a non-redundant role for beta4GalT1 in the regulation of beta1

230 We have resolved an essential and non-redundant role for DNA ligase 1 in the fusion of sister

231 of the apical marker Uninflatable and a non-redundant role for the Na(+)/K(+) ATPase in apical marke

232 hat these two proteins play an essential and redundant role in bacterial microcompartment assembly th

233 e conclude that IgA plays a critical and non-redundant role in controlling gut microbiota composition

234 vous system (ENS) plays an essential and non-redundant role in governing the antimicrobial protein (A

235 c receptor 8a (IR8a) plays a primary and non-redundant role in human host-seeking behaviors.

236 rgeting Wilms tumour cancer genes with a non-redundant role in nephrogenesis and targeting the fetal

237 states, while A. muciniphila may play a non-redundant role in patients with a severe asthma phenotyp

238 10,11, Hoxc9,10,11, Hoxd9,10,11 genes play a redundant role in the formation of uterine glands.

239 rved in THP-1 cells, possibly explaining the redundant role of NLRP3 and NAIP/NLRC4 during S. Typhimu

240 bserved in SlPIF4-silenced fruits revealed a redundant role of SlPIF4 in the accumulation of nutraceu

241 genes in mice and that many KRAB-ZFPs play a redundant role restricting TE activity.

242 and ORP10 are required, with OSBP1 playing a redundant role with ORP9, which does not involve its lip

243 The data reveal critical and non-redundant roles for Ano1 in organogenesis, and show that

244 effects on circadian period, suggesting non-redundant roles in circadian gene regulation.

245 atekeepers" of the ERK signaling output with redundant roles in controlling ERK activity.

246 In THP-1 cells, NAIP/NLRC4 and NLRP3 played redundant roles in inflammasome activation during infect

247 Thus, Thm1 and Thm2 have unique and redundant roles in MEF.

248 se results suggest that WAVE1 and WAVE2 have redundant roles in promoting Arp2/3-dependent actin nucl

249 dicates that the paralogues have shared, non-redundant roles in regulating osteoclast activity during

250 genes VRN1, FUL2 and FUL3 play critical and redundant roles in spikelet and spike development, and a

251 SYP-6 are paralogous to each other and play redundant roles in synapsis, providing an explanation fo

252 its related paralog AP2L2 play critical and redundant roles in the specification of axillary floral

253 toplasm, indicating that the two ZFs display redundant roles in this respect.

254 In particular, our earlier findings support redundant roles of NLR family pyrin domain-containing 3

255 we show that Nr4a1 and Nr4a3 play partially redundant roles to restrain B cell responses to antigen

256 RUNX1 plays complementary/redundant roles with FOXL2 to maintain fetal granulosa c

257 The USP20 homolog USP33, which shares redundant roles with USP20, had no effect on beta(1)AR u

258 drugs, are often considered to have largely-redundant roles.

259 Redundant self-motion responses may provide the brain wi

260 were added to the database after removal of redundant sequences and analysis of the remaining allele

261 Next, we analyzed the 43 million non-redundant sequences from the M5nr data and identified 32

262 cts in a variety of RNA molecules from a non-redundant set of crystal structures with resolution <=3.

263 We developed a non-redundant set of five quality control (QC) measurements

264 ots, the possibility to analyze all or a non-redundant set of proteins, and various technical updates

265 Whereas redundant SHOC2-dependent and -independent mechanisms of

266 A strategy is presented involving the use of redundant site labeling data from overlapping peptides,

267 ses dependence on the otherwise functionally redundant SoxR-regulated superoxide dismutase.

268 cally justified, statistically valid and non-redundant specifications; (2) displaying the results gra

269 A total of 3607 non-redundant SSR primer pairs was designed based on the seq

270 for fetal hemoglobin (HbF) control is a non-redundant subcomplex of NuRD protein family paralogs, wh

271 glycosylation of apolipoprotein C-III, a non-redundant substrate for GALNT2.

272 released from its precursor by a network of redundant subtilases.

273 ontology structure to provide a concise, non-redundant summary that can be expanded to reveal underly

274 First, redundant supracellular cytoskeletal network paths ensur

275 Redundant synaptic connections are removed in a process

276 nnotator (EDTA) that produces a filtered non-redundant TE library for annotation of structurally inta

277 ) binding data, we recover consolidated, non-redundant TF motifs.

278 they impact cellular phosphorylation and how redundant they are in cellular regulation is poorly unde

279 ation events, albeit in a manner genetically redundant to CPF.

280 e here PgnE, that appears to be functionally redundant to pelX In line with this, a DeltapelX Deltapg

281 1 locus on the pRAW plasmid, is functionally redundant to the protease domain of MycP(5) These result

282 NHE is a non-redundant toxin to haemolysin BL (HBL) despite having a

283 nded to consider YAP and TAZ as functionally redundant transcriptional cofactors with similar biologi

284 Exclusion prevents the redundant transfer of conjugative elements into host cel

285 an cells with a full capacity to up-regulate redundant transporters by an integrated stress response.

286 localize to the septum and are functionally redundant under normal laboratory conditions; however, o

287 vidual receptor, provides clear evidence for redundant use of these receptors in establishing tissue-

288 Information can be redundant, useful common representations of multimodal d

289 domain architecture but are functionally non-redundant: USP28 stabilizes c-MYC and other nuclear prot

290 plant recipients, items deemed irrelevant or redundant were dropped.

291 arly regulate axon turning, are functionally redundant with each other, and that Fzd3 genetically int

292 ependent and that NPD family members are not redundant with regard to their effects on rhizobial stra

293 The function of MSTN is partially redundant with that of another TGF-beta family member, a

294 t even though UAF1's DNA-binding activity is redundant with that of RAD51AP1 in FANCD2 deubiquitinati

295 that progress notes were, on average, 74.5% redundant with the prior progress note written for the s

296 d were long believed to play roles that were redundant with those of type I IFNs.

297 KDM6A is redundant with UTY and functions largely independently o

298 the past it was thought that ncRNAs would be redundant without relevant functions, it is now well est

299 Utilization of redundant working electrodes improves the measurement ac

300 We apply the strategy to a particularly redundant yet disease-relevant human glycosyltransferase