ライフサイエンスコーパス: regeneration

1 ry, and new methods to study lung repair and regeneration.

2 velopment and the dynamics of injury-induced regeneration.

3 ulations to embryonic development and tissue regeneration.

4 sis and toward PL synthesis may promote axon regeneration.

5 transitional stem cell state during alveolar regeneration.

6 treatments for vital pulp therapy and dentin regeneration.

7 g therapeutic target for human sensory nerve regeneration.

8 ack of informative adult mammalian models of regeneration.

9 p" for pathways that control human beta cell regeneration.

10 ing endothelial proliferation and LepR+ cell regeneration.

11 or Myc as a therapeutic target for beta-cell regeneration.

12 animals to identify genes essential for limb regeneration.

13 establishing where a lesion is conducive for regeneration.

14 scularization-mediated diabetic wound tissue regeneration.

15 giogenesis, fertilization, wound healing and regeneration.

16 of inflammation, bridging healing and tissue regeneration.

17 inflammation, organ development, and tissue regeneration.

18 l proliferation, leading to early urothelial regeneration.

19 igration and their contribution to epidermal regeneration.

20 he components has been shown to influence HF regeneration.

21 this proliferation is critical to successful regeneration.

22 e characteristics, resulting in robust heart regeneration.

23 sues harbor progenitors capable of mediating regeneration.

24 tes and how this might relate to renewal and regeneration.

25 for addressing patterning mechanisms during regeneration.

26 ow clinically distinct recovery patterns and regeneration.

27 more complex picture of polyploidy in heart regeneration.

28 hepatocytes did not noticeably impair liver regeneration.

29 that knocking out PAR1 also promotes myelin regeneration.

30 blood flow and accelerated the wound tissue regeneration.

31 of the cell types participating in digit tip regeneration.

32 otype in injured muscle profoundly influence regeneration.

33 anipulate cell motility in disease or tissue regeneration.

34 , longitudinal study of pancreatic endocrine regeneration.

35 molecules to support wound healing and bone regeneration.

36 atellite cells during homeostasis and muscle regeneration.

37 tion of inflammation, resolution, and repair/regeneration.

38 n and are a potential approach for cartilage regeneration.

39 nsitivity to dim conditions and high retinal regeneration.

40 +/- 1.81 mm) were treated with guided tissue regeneration.

41 rlying the evolution of multicellularity and regeneration.

42 tty acid synthase (Fasn) in SGC impairs axon regeneration.

43 creased Hippo activity, and suppressed liver regeneration.

44 ment, suggesting a specific role in dendrite regeneration.

45 e nucleation at baseline and during dendrite regeneration.

46 in the proliferating progenitors during limb regeneration.

47 gulates development, tissue homeostasis, and regeneration.

48 apeutic opportunity to improve hematopoietic regeneration.

49 , also facilitates cell division and cardiac regeneration.

50 nases that regulated neuronal death and axon regeneration.

51 jury alterations of gene expression in liver regeneration.

52 gions that gain accessibility during cardiac regeneration.

53 ermine the location of fin ray joints during regeneration.

54 vement of Wnt signaling proteins in dendrite regeneration.

55 -lineage cells during injury repair and lung regeneration.

56 , sarcolemmal fragility, and impaired muscle regeneration.

57 ta A (inhba), a known effector of vertebrate regeneration.

58 iomyocyte proliferation and subsequent heart regeneration.

59 induced proliferation required for efficient regeneration.

60 arly calcium signaling and subsequent tissue regeneration.

61 ental models of stem cell biology and tissue regeneration.

62 lls and molecular pathways that drive tendon regeneration.

63 olecular pathway that drives neonatal tendon regeneration.

64 family, and is critically involved in tissue regeneration.

65 spatiotemporal gene expression during heart regeneration.

66 enitors (DATPs), that arises during alveolar regeneration.

67 uld have therapeutic potential for beta-cell regeneration.

68 laments and in protoplasts before and during regeneration.

69 gical effects of materials, tissue and organ regeneration.

70 , and is cell-autonomously required for axon regeneration.

71 th O(2) allows H(2) O(2) accumulation and AQ regeneration.

72 cteristics to instruct organ development and regeneration(1,2).

73 inflammation, cell proliferation, and tissue regeneration(2-4).

74 To investigate the effects of CES on nerve regeneration, a series of kinetic, kinematic, skilled lo

75 urvival and proliferation, and overall heart regeneration, accompanied by decreased fibrosis.

76 ocyte progenitor cells maturation and myelin regeneration across the remyelination phase of the cupri

77 parameters, ischemia-reperfusion injury and regeneration after hepatectomy.

78 n patterns and transcriptomes, promotes axon regeneration after injury, and reverses vision loss in a

79 pports development, synaptic plasticity, and regeneration after injury.

80 l cycle entry and potentially cardiac tissue regeneration after injury.

81 Neonatal mice exhibit natural heart regeneration after myocardial infarction (MI) on postnat

82 pave the way to applications such as cardiac regeneration after myocardial infarction and gene correc

83 regulatory mechanisms to enhance myocardial regeneration after myocardial infarction.

84 tial for Schwann cell myelination and myelin regeneration after nerve injury.

85 During regeneration after transection, the spinal cord tissues

86 perimetry is a powerful tool to capture cone regeneration after vitreoretinal surgery.

87 audal fin regeneration and abrogated cardiac regeneration altogether.

88 nd its genomic deletion perturbed caudal fin regeneration and abrogated cardiac regeneration altogeth

89 ulate functionally distinct phases of airway regeneration and aging.

90 bx3 and Meis1 as critical regulators of tail regeneration and axon organization.

91 Despite its pivotal role in homeostasis, regeneration and cancer, little is known about the post-

92 erimentally demonstrate simultaneous solvent regeneration and CO(2) desorption in a continuous system

93 nical changes that accompany skeletal muscle regeneration and determined the implications on SC fate.

94 ts uncover a mechanism that controls myeloid regeneration and early lineage decisions in HSCs and cou

95 may provide a new option for promoting axon regeneration and functional recovery after CNS trauma.

96 apidly after injury and necessary for axonal regeneration and functional recovery.

97 nitor proliferation during retinogenesis and regeneration and glia proliferation in proliferative ret

98 effectiveness of this biomaterial for tissue regeneration and in vivo restoration of organ functions.

99 Their silencing promotes faster regeneration and increases cell number during homeostasi

100 ion of Csnk2a1 mRNA from PNS axons decreases regeneration and increases G3BP1 granules.

101 sive disability because of failure of myelin regeneration and loss of neurons, suggesting additional

102 -derived NRG1 is a potent mediator of tissue regeneration and may inform the development of therapies

103 molecular and cellular determinants of nerve regeneration and neuropathic pain in humans.

104 l injury model used to examine mechanisms of regeneration and repair in organs.

105 naling pathway and are essential for cardiac regeneration and repair.

106 The regeneration and reusability studies of spent PNHM/Fe(3)

107 Further testing on the POP nanotrap regeneration and selectivity found that POP-oNH(2) -Py o

108 ve factors and PET incorporation have on ACL regeneration and signal a promising step toward the clin

109 human tissues identified processes of tissue regeneration and stem cell regulation.

110 g adsorption efficiency after electrothermal regeneration and the great adsorption efficiency of HNO(

111 milarities between wound healing, epimorphic regeneration and the progression of solid tumors have be

112 ent the endogenous osteogenic cells for bone regeneration and the treatment of bone loss.

113 ate epithelial cell growth during intestinal regeneration and tumorigenesis.

114 between stroma and epithelium during tissue regeneration and tumorigenesis.

115 binding growth factors inducing greater bone regeneration and wound repair than wild-type growth fact

116 pathetic innervation, promoted sensory nerve regeneration, and alleviated disease.

117 ample type with dynamic accessibility during regeneration, and assigned these regions to proximal gen

118 cification is critical for skin development, regeneration, and evolution.

119 tic potential to promote human hematopoietic regeneration, and further studies are warranted to asses

120 rates, grazing, growth, calcification, spine regeneration, and gonad production under constant, 3-hou

121 ocyte, its antagonistic effect on myocardial regeneration, and its potential contribution to cardiac

122 tion signatures are stably maintained during regeneration, and regeneration enhancers are preset as h

123 ls and exhibit delayed and protracted muscle regeneration, and satellite cell-derived myogenic cells

124 ed pro-survival signaling, dampens AML blast regeneration, and strongly synergizes with chemotherapy,

125 ed at the injury site during zebrafish heart regeneration, and that absence of runx1 results in incre

126 renal mass reduction, indicating that kidney regeneration approaches, besides whole kidney reconstruc

127 Regulatory networks important for regeneration are constructed through integrative analysi

128 ng, strategies for the induction of neuronal regeneration are desperately needed.

129 the molecular mechanisms that underlie this regeneration are unknown.

130 gingival HIF-1alpha protein levels and bone regeneration, as compared to mice treated with vehicle c

131 ination in cortex changed dramatically after regeneration, as new oligodendrocytes were formed in dif

132 architectural cues that promote in situ bone regeneration at locations distant from existing host bon

133 Hydroxide base regeneration at low temperatures was observed for the fi

134 tory of reduced maize cultivation and forest regeneration at mid-elevation.

135 The BioCer implant promoted bone regeneration at nonosseous sites, and bone bonding to th

136 r a mammal, it displays surprising powers of regeneration because it does not fibrose (i.e. scar) in

137 ing to their impacts on forest structure and regeneration, biodiversity, and ecosystem services.

138 rowing tissues is crucial in development and regeneration but remains poorly understood.

139 sion with short hairpin RNA (shRNA) improves regeneration but to a lesser extent, likely due to subop

140 The PLT-CUC2 module is required for vascular regeneration, but is dispensable for midvein formation i

141 uiescence to activation that is required for regeneration, but it remains unknown if the trajectory a

142 Growth factors can stimulate tissue regeneration, but the side effects and low effectiveness

143 late-bud) and studied its role during tissue regeneration by ablating the function of one of its comp

144 results demonstrate that Protrudin promotes regeneration by functioning as a scaffold to link axonal

145 ds the rate of ATP turnover in cells, NAD(+) regeneration by mitochondrial respiration becomes constr

146 e witnesses but contribute to protection and regeneration by producing HS.

147 This mechanism of suppressing regeneration by silencing damage-responsive enhancers at

148 gas mixtures, this material shows excellent regeneration capability when releasing the external mech

149 eration in intestinal crypts and compromises regeneration capacity.

150 e took advantage of naturally occurring tail regeneration-competent and -incompetent developmental st

151 not only enhanced axon regeneration in both regeneration-competent and -incompetent sensory neurons

152 myeloid lineage for tail regeneration in the regeneration-competent tadpoles.

153 Regeneration-competent vertebrates are considered to sup

154 d techniques are able to promote periodontal regeneration coupled with the provision of tooth root co

155 Tissue regeneration declines with ageing but little is known ab

156 Muscle regeneration depends on a robust albeit transient inflam

157 sensitivity in most of them thanks to nerve regeneration documented by IVCM.

158 Hg(0) adsorption and regeneration efficiencies of raw and HNO(3)-treated acti

159 to 450 degrees C) and aqueous stability, low regeneration energy, and a high degree of chemical and g

160 To identify candidate tissue regeneration enhancer elements (TREEs) important for zeb

161 We dissected a cardiac regeneration enhancer in zebrafish to elucidate the mech

162 This analysis also revealed that cardiac regeneration enhancers are not only activated by injury,

163 e stably maintained during regeneration, and regeneration enhancers are preset as hypomethylated befo

164 Desorption and regeneration experiments revealed that TLSB could be des

165 organogenesis, promote tissue protection or regeneration, facilitate antimicrobial responses, and di

166 Axon regeneration failure causes neurological deficits and lo

167 te that FoxM1 is important for renal tubular regeneration following AKI and that GSK3beta suppresses

168 ly studied for its role in inhibiting axonal regeneration following injury to the central nervous sys

169 eased muscle fibrosis and increased myofiber regeneration following IR injury, suggesting short-term

170 premature involution and orchestrates thymic regeneration following stress, while thymocyte-derived L

171 d Wnt signaling transiently triggers myeloid regeneration from HSCs in response to stress, and that c

172 regenerative capabilities, fish have robust regeneration from Muller glia (MG).

173 ity of the new bone formation in guided bone regeneration (GBR) procedures with different titanium me

174 ctive tissue grafting (CTG) or guided tissue regeneration (GTR) using bioabsorbable barriers for root

175 trol is a major determinant of guided tissue regeneration (GTR).

176 lopmental processes underlying normal tissue regeneration have been implicated in cancer, but the deg

177 ex, and premature claims of successful heart regeneration have both fueled interest and created contr

178 nces of transcriptional programs during lung regeneration have remained elusive.

179 promote neuroprotection by enhancing myelin regeneration, hence restoring nerve conduction and metab

180 NT Replacement of oligodendroglia and myelin regeneration holds tremendous potential to improve funct

181 undamental role biodiversity plays in forest regeneration, identifying and prioritizing degraded fore

182 d hemostatic hydrogels as a scaffold on pulp regeneration in a minipig model.

183 proteins amplify Wnt signaling and stimulate regeneration in a variety of tissues.

184 or optoAKT activation not only enhanced axon regeneration in both regeneration-competent and -incompe

185 ew PANk2(-/-) knockout model that allows CoA regeneration in brain cells to be evaluated and describe

186 als while exhibiting features in common with regeneration in lepidosaurs and amphibia.

187 factor (GDNF) induces enteric nervous system regeneration in mouse models of HSCR.

188 KKepsilon) have shown to stimulate beta-cell regeneration in multiple species.

189 acerbating chronic inflammation and reducing regeneration in old age.

190 is an osteoinductor frequently used for bone regeneration in oral and maxillofacial surgery.

191 e for their functions, and tissue repair and regeneration in renal diseases.

192 ith hair follicle stem cells to promote hair regeneration in response to cold.

193 ated intestinal epithelial proliferation and regeneration in response to mucosal damage.

194 Moreover, GRF4-GIF1 induced efficient wheat regeneration in the absence of exogenous cytokinins, whi

195 s for these cellular components in mediating regeneration in the adult central nervous system.

196 oferrins in hepatocytes dramatically reduced regeneration in the adult mouse liver, further supportin

197 ing myelination after injury and during axon regeneration in the central nervous system (CNS).

198 n is thus a promising strategy to promote HC regeneration in the mature mammalian cochlea.

199 The main limitation on axon regeneration in the peripheral nervous system (PNS) is t

200 sential role of the myeloid lineage for tail regeneration in the regeneration-competent tadpoles.

201 ome exhibited therapeutic potential for lung regeneration in two experimental models of pulmonary fib

202 We show that hematopoietic regeneration in vivo following total body irradiation is

203 GF promotes HSC DNA repair and hematopoietic regeneration in vivo via augmentation of NHEJ.

204 europrotective properties and drove CNS axon regeneration in vivo, in part via secretion of a cocktai

205 mation in vitro and prostate epithelial duct regeneration in vivo.

206 miR-206 is required for skeletal muscle regeneration in vivo.

207 US morphometric parameters to quantify bone regeneration in vivo.

208 nesis and on nascent myofibers during muscle regeneration in vivo.

209 tion of a drug that is able to induce axonal regeneration in vivo.

210 tially increases the efficiency and speed of regeneration in wheat, triticale and rice and increases

211 We have identified a case of regeneration in Xenopus embryonic aggregates that restor

212 erative cell type that promotes healthy skin regeneration in young skin.

213 viously unrecognized roles of PAR1 in myelin regeneration, including integrated actions across the ol

214 Moreover, treatment of regeneration-incompetent tadpoles with immune-suppressin

215 cellular mechanisms failed to be executed in regeneration-incompetent tadpoles.

216 ated deacetylase HDAC6, which functions as a regeneration inhibitor.

217 Self-regeneration is a fundamental function of all living sys

218 ts impact on ischemia-reperfusion injury and regeneration is unknown.

219 both factors concurrently on cementum and AB regeneration, mandibular fenestration defects were creat

220 We suggest that certain mechanisms enabling regeneration may be co-opted by cancer to promote growth

221 ic acid, namely maresin conjugates in tissue regeneration (MCTRs), were recently discovered.

222 A new dye regeneration mechanism is proposed in which electrons ar

223 nt insights into the complex development and regeneration mechanism of the retina and may offer a new

224 A Hg adsorption/regeneration mechanism was proposed to explain the incre

225 nt epithelial cells is impaired, alternative regeneration mechanisms can occur.

226 lagen sponge (ACS) in a vertical guided bone regeneration model.

227 frequently proposed therapies included cell regeneration (n = 115, 39.4%) mainly for treatment of ne

228 ds involved new drugs (n = 149, 51.0%), cell regeneration (n = 115, 39.4%), and immune and inflammato

229 ively active Pfn1 to rodents promoted axonal regeneration, neuromuscular junction maturation, and fun

230 The regeneration of ACFC was done by an electrothermal swing

231 of P-TEFb levels could be utilised to drive regeneration of adult cardiomyocytes for the treatment o

232 After trauma, regeneration of adult CNS axons is abortive, causing dev

233 rategy to promote functionally-relevant axon regeneration of adult neurons into the CNS after injury.

234 axis being essential for the maintenance and regeneration of both EMRMs and BMRMs.

235 al progenitor cells (NPCs) enable the robust regeneration of corticospinal axons and restore forelimb

236 hannels negatively regulates axon growth and regeneration of corticospinal neurons, the cells that or

237 ination with CM, may improve the periodontal regeneration of dehiscence-type defects in this animal m

238 n is delayed and conditioning-lesion-induced regeneration of DRG neuron central axons is abolished.

239 rogate sires as a tool for dissemination and regeneration of germplasm in all mammalian species.

240 bronchus-associated lymphoid tissue, induced regeneration of lung tissue, and reverted airway fibrosi

241 n on their surface potently inhibited axonal regeneration of mechanically injured cerebral cortex neu

242 characterized by cycles of degeneration and regeneration of multinucleated myofibers and pathologica

243 Remyelination is the regeneration of myelin sheaths following demyelination.

244 pends on the lactate dehydrogenase-catalyzed regeneration of NAD(+) from GAPDH-generated NADH because

245 demonstrated epithelial ablation followed by regeneration of normalized epithelium.Objectives: To eva

246 Mechanistically GLP-2 substitution promoted regeneration of PCs and ISCs, which enhanced production

247 all embryonic tendon cells and find complete regeneration of tendon structure and pattern.

248 velopment have been applied to interrogating regeneration of the diseased heart, exemplifying the imp

249 en deprivation, and do not contribute to the regeneration of the distal luminal compartments.

250 Following the removal process, efficient regeneration of the electrode is achieved at -1.2 V wher

251 tem cells fuel development, homeostasis, and regeneration of the epidermis.

252 ot clear how its activation affects ISCs and regeneration of the intestinal epithelium.

253 re we resolve the function of YAP/TAZ during regeneration of the liver, where Hippo's role in growth

254 r defects in vitamin A metabolism during the regeneration of the visual pigments required for the det

255 ons and tissue culture methods for efficient regeneration of transplastomic plants.

256 olves farmers selecting and managing natural regeneration on their fields, while keeping them under t

257 Ror was not required for axon regeneration or normal dendrite development, suggesting

258 signals via endothelial niche S1PR1 to spur regeneration over fibrosis.

259 animals had significantly accelerated nerve regeneration (p < 0.001), increased walking speed, and i

260 ve, in-depth perspective on peripheral nerve regeneration, particularly nerve guidance conduits and d

261 a potential and novel approach for cementum regeneration, particularly targeting ENPP1 and/or ANK.

262 h populations contribute equally to prostate regeneration, partly through androgen-driven expression

263 of the myeloid lineage on the creation of a regeneration-permissive environment and could be further

264 ystems biology approaches to models of liver regeneration, pharmacologically and genetically activate

265 on injury and during the early stages of the regeneration process.

266 genosis" to describe this conserved cellular regeneration program.

267 The donor plants prepared for regeneration purposes had 5.75% and 2.01% polymorphic me

268 mpaired at the G1/S and G2/M transitions and regeneration rate was reduced.

269 s of the TGF-beta family, including neuronal regeneration-related protein (NREP) and growth different

270 ell-derived cardiomyocytes can affect "heart regeneration", replacing injured cardiac scar tissue wit

271 Vertebrate appendage regeneration requires precisely coordinated remodeling o

272 The conserved response revealed several regeneration-responsive enhancers (RREs), including an e

273 KT differ in their signaling kinetics during regeneration, showing a gated versus graded response, re

274 ter, population size, apoptotic markers, and regeneration signaling.

275 s signaling to enhance neurite outgrowth and regeneration.SIGNIFICANCE STATEMENT SORLA is a transmemb

276 The clinical use of SCs in nerve regeneration strategies is hindered by the necessity of

277 evelopment of new clinically relevant myelin regeneration strategies.

278 inflammatory response during skeletal muscle regeneration, suppressed Fbxl2 mRNA expression in C2C12

279 ical research phase for the testing of heart regeneration therapies.

280 a novel role for sSORLA in promoting neurite regeneration through the EGF receptor/ERK/Fos pathway, t

281 bute to the understanding of skeletal muscle regeneration through the identification of Fbxl2 as both

282 c barriers that must be overcome for cardiac regeneration to occur.

283 insic, local, and systemic stimuli to adjust regeneration to tissue demands.

284 predicted upstream regulator disrupts normal regeneration, validating our prediction.

285 diverse processes in cancer, development and regeneration, via Hippo pathway and cytoskeleton regulat

286 In addition, dendrite regeneration was sensitive to partial reduction of gamma

287 Guided bone regeneration was the intervention most commonly applied

288 To develop means to augment tendon regeneration, we have previously prepared a soluble, low

289 Using a mouse model of neonatal tendon regeneration, we identified TGFbeta signaling as a major

290 elements (TREEs) important for zebrafish fin regeneration, we performed ATAC-seq from bulk tissue or

291 s and some new mechanisms involved in axonal regeneration were identified.

292 s biomaterials have positive effects on bone regeneration when used for repair of bone defects.

293 urine digit has been used to study mammalian regeneration, where stem/progenitor cells (the "blastema

294 cence to reactivity is essential for retinal regeneration, whereas in mice, a dedicated network suppr

295 wing ablation enabled spontaneous macrophage regeneration, which fully restored original macrophage d

296 s during infection and preventing epithelial regeneration, which prolongs epithelial barrier impairme

297 ded if they have both exotropia and aberrant regeneration with a ptosis that improved on adduction.

298 istant from existing host bone, whereas bone regeneration with inert titanium implants was confined t

299 ore, surface states significantly affect dye regeneration (with I(-)/I(3)(-) as redox couple) and hol

300 development, epithelial homeostasis, tissue regeneration, wound healing and immune modulation.