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1 in neural circuits is believed to be tightly regulated.
3 g development, signaling by this superfamily regulates a variety of embryological processes, and it h
4 rophage migration inhibitory factor (MIF) in regulating a metabolic rhythm in the model light-organ s
5 elongation response to auxin, most likely by regulating a subset of auxin inducible genes related to
9 cell stress and nutrient deprivation can up-regulate and activate DinB/pol IV, the bacterial ortholo
10 osuppressive B7 family members, yet how they regulate and coordinate alphabeta and gammadelta T cell
13 UBR5, and to a lesser degree UBR4, were down-regulated as cellular demand for antibody expression inc
14 we sought to investigate the mechanisms that regulate AXL over-expression in pancreatic ductal adenoc
15 is pleiotropic cytokine, including how IL-10 regulates basic processes of neural and adipose cells an
18 over, expression of the c-di-GMP and calcium-regulated, biofilm-promoting brp exopolysaccharide was I
19 nally, a rescue experiment revealed that YY1-regulated BMP6 expression in ECs was involved in EC migr
22 ue and its microbial and dietary content(1), regulating both physiological intestinal functions such
26 diverse substrates whose activities are down-regulated by acylation but are required for biofilm form
27 as others are ubiquitously expressed but are regulated by AD risk variants within myeloid enhancers i
31 r, our findings define a metabolic mechanism regulated by astrocytic alpha2-Na/K ATPase that triggers
32 reviously reported enhancer regions of genes regulated by ATOH1, including genes that encode Delta-li
33 at expression of m(6)A demethylase ALKBH5 is regulated by chromatin state alteration during leukemoge
34 Mitochondrial fission and fusion are highly regulated by energy demand and physiological conditions
36 led 19 new cases of genes whose integrity is regulated by IGEs (including dut, eccCa1, gntT, hrpB, me
38 nt stages of myogenesis are orchestrated and regulated by myogenic regulatory factors and various dow
40 s with increased expression were known to be regulated by peroxisome proliferator-activated receptor
41 ivation is dually dependent on and bimodally regulated by phosphatidylinositol 4,5-bisphosphate (PIP(
43 sites by the core spliceosomal machinery is regulated by several protein factors that predominantly
44 in growth and virulence by identifying genes regulated by SpxA1 in broth and during macrophage infect
45 emonstrate that cell shape in V. cholerae is regulated by the bacterial second messenger cyclic dimer
46 us, the competence state in cyanobacteria is regulated by the circadian clock and can adapt to season
47 lls that Fes1 oxidation is reversible and is regulated by the cytoplasmic methionine sulfoxide reduct
48 se mammary tumor cells, PD-L1 expression was regulated by the nuclear receptor NR4A1/Sp1 complex boun
51 2 are paralogous transcription factors (TFs) regulated by the Ssy1-Ptr3-Ssy5 (SPS) amino acid sensing
52 triggered oviposition in these mosquitoes is regulated by the stress- and immune-responsive c-Jun N-t
53 c O(2) and [Formula: see text] are primarily regulated by their relative partial pressures, [Formula:
55 Ca(2+) responses, the importance of tightly regulated Ca(2+) dynamics for mitochondrial axonal trans
56 Spatial variations in collagen organization regulate cardiac fibroblast phenotype through mechanical
59 It largely localizes in the cell nucleus and regulates CD39 by interacting with nucleolin and heterog
60 Additionally, TCR signal strength is able to regulate CD8(+) T cell effector cytokine R production in
71 ngs identify a widely distributed NREM sleep-regulating circuit in the brainstem with a common molecu
73 eveal effector-triggered and phosphorylation-regulated conformational changes within RRS1 that result
74 ally interacts with SERCA and differentially regulates contractility in skeletal and atrial muscle.
76 are highly dependent on circadian clocks to regulate critical behaviors, such as foraging orientatio
78 ulates LFA1-mediated adhesion and positively regulates CXCL12-induced migration in DN thymocytes.
83 mate and inhibitory neurotransmitter GABA in regulating delay activity in rhesus monkeys performing a
84 rgo trafficking; however, the mechanism that regulates dendritic microtubule organization is still un
86 he capability to design high-performance ion-regulating devices and promotes the utilization of susta
87 re we show that aerobic exercise training up-regulates DICER in adipose tissue of mice and humans.
88 gnaling strength and genetically interact to regulate digit number, body patterning, and cardiac deve
89 and ChIP-seq approaches we identified genes regulated directly and indirectly by RFX1, RFX2 and RFX3
91 recent studies have shown that MAGE proteins regulate diverse cellular and developmental pathways, im
93 omixotrophy, the cell must therefore tightly regulate electron fluxes from photosynthetic and respira
94 Here, we report a function of human DBC1 in regulating ELL stability involving HDAC3, p300, and Siah
95 histones by PADI4 was recently implicated in regulating embryonic stem and hematopoietic progenitor c
96 copies LSD1 inhibition, suggesting that LSD1 regulates endocrine cell differentiation by limiting the
103 n of a fusion protein combining wheat GROWTH-REGULATING FACTOR 4 (GRF4) and its cofactor GRF-INTERACT
106 t, but little is known about the molecule(s) regulating FGF signaling during nephron development.
111 gulation and unbiased interrogation of USP22-regulated functions in vitro demonstrated critical roles
116 r, these results demonstrate that holo-WhiB1 regulates gene expression by a non-canonical mechanism r
119 evious transcriptomic findings of miR-128 in regulating gene networks that govern membrane excitabili
121 thus information about posttranscriptionally regulated genes and associated networks is lacking.
122 st exposure were enriched for glucocorticoid-regulated genes and immune pathways with some of these g
127 eveal a mechanism by which satellite repeats regulate global gene expression in trans via piRNA-media
128 PP)(2)-InsP(4) impacts beta-cell activity by regulating granule localization and/or priming and calci
129 Consistent with a role for the G-proteins in regulating GSC division frequency, RNA-i against seven o
130 r/PI3K/protein kinase B-dependent manner, to regulate hepatic acetyl-CoA and cholesterol synthesis.
133 inal BAs(2) that are important hormones that regulate host cholesterol metabolism and energy balance
134 nized defense machineries, which can jointly regulate host-derived danger molecule signaling and inte
135 s, Fgl2 is a TFR cell effector molecule that regulates humoral immunity and limits systemic autoimmun
136 RS knockdown alters HuR cytosolic shuttling, regulating HuR targets such as p53, p27, Caspase-9, and
138 our results demonstrated that stromal Lama5 regulated immune responses through altering LN structure
139 IL-2) is a small alpha-helical cytokine that regulates immune cell homeostasis through its recruitmen
142 ed expression of the stress response protein regulated in development and DNA damage 1 (REDD1) is nec
144 ally enriched for genes that are commonly de-regulated in PDAC tumors upon activation of KRAS and ina
145 ulator of adipocyte differentiation, is down-regulated in RCC and shows a differential expression pat
146 ators of gene expression that are aberrantly regulated in several inflammatory and infectious disease
149 whole pancreas, has long been believed to be regulated independently from the surrounding exocrine ti
150 small non-coding RNAs which are reported to regulate inflammatory response and cell proliferation.
151 are crucial for understanding how the brain regulates information flow across senses to interact wit
152 g pathway, will shed light on the origins of regulated innate immunity, and may have relevance to our
153 Kindlins are focal adhesion proteins that regulate integrin activation and outside-in signaling.
157 formin-regulated miRNAs and that some of the regulated isomiRs (e.g. the 5' miR-217 isomiR) are endow
161 f MAPK kinase (MEK) and extracellular signal-regulated kinase 1/2 signaling; however, the clinical ef
162 phosphorylation of ERK (extracellular signal-regulated kinase), JNK, and p38 mitogen-activated protei
165 Furthermore, we show that WNK1 negatively regulates LFA1-mediated adhesion and positively regulate
166 f-containing nuclear localized (AHL) protein regulates lipid mobilization and fatty acid beta-oxidati
167 lin, we studied the mechanisms by which LNSC regulate low-avidity autoreactive cells in the NOD mouse
168 ciprocally, caspase-1, as well as caspase-8, regulated LUBAC activity by proteolytically processing H
169 s, mTNF alone is necessary and sufficient to regulate lung inflammation but it has no direct antivira
174 tate cancers functions in a negative role in regulating MEIS1 expression, and that this down-regulati
175 tigens that have been identified thus far to regulate members of the human Vdelta1 population and dis
176 le factor-dependent signaling, which in turn regulates metabolic reprogramming, immune suppression, r
177 nutrient sensing are modulated by metformin-regulated miRNAs and that some of the regulated isomiRs
178 e collection identified chemical probes that regulate mitochondrial membrane potential, adenosine 5'-
180 a role for mitochondria-lysosome contacts in regulating mitochondrial calcium dynamics through the ly
182 d in reward-related brain areas, its role in regulating motivation and preference for nutrients has n
183 Among the many cellular mechanisms that regulate mRNA fate, covalent nucleotide modification has
186 se findings demonstrate that BRD4 negatively regulates MYC levels, which is counteracted by ERK1 acti
190 ent of carbohydrates to proteins and lipids, regulates nearly all cellular processes and is critical
192 tion plays a crucial role in maintaining and regulating neural function, and importantly its dysfunct
193 -helix-orange transcriptional repressor that regulates neurogenesis in several developmental contexts
196 ht the ways in which STEP(61) differentially regulates NMDARs and AMPARs, as well as its role in plas
198 ription on chromosome arms, yet how the cell regulates nuclear and chromatin-associated RNAs after ch
199 The small and transient actin structures regulating organelle dynamics are challenging to detect
200 non-traditional immunological functions that regulate organismal metabolism by controlling insulin ac
201 conclusion, orchestrated T cells are able to regulate osteoclasts at the early stage of rapid palatal
202 ight into how a unique collagen fragment may regulate ovarian cancer, but in addition may help provid
205 endently of PM depolarization and negatively regulates pathogen-associated molecular pattern-triggere
207 f cells, including the vascular endothelium, regulates permeability, leukocyte traffic, nitric oxide
209 d SAR in jmj14 plants, suggesting that JMJ14 regulated Pip biosynthesis and other downstream factors
210 E transcription factors BPC1/BPC2 positively regulate plant salt tolerance by repressing GALS1 expres
211 ike protein kinases (RLKs) play key roles in regulating plant growth, development and stress adaptati
213 The LIN28:pre-let-7:TUTase ternary complex regulates pluripotency and oncogenesis by controlling pr
216 re clear roles for branched architectures in regulating proteasome-mediated degradation, but the prot
218 as a new posttranslational modification that regulates protein synthesis during cellular response to
222 tofrontal cortex (OFC) and the opioid system regulate reward, motivation, and food intake, understand
225 al support for roles for PME-1 and LCMT-1 in regulating sensitivity to Abeta-induced impairments, and
227 r units and propose that the developmentally regulated silencing of ESRRB triggers the selective inac
232 of lineage-defining transcription factors in regulating specification programs of innate and adaptive
239 chanism for social memory formation, through regulating synaptic receptor trafficking in pyramidal ne
243 In this study, we show that PIFs positively regulate the ABA signaling pathway during the seedling s
246 methylation in silencing transposons and to regulate the expression of CG/CHG-depleted transposons.
247 be distinguished by the capacity of cells to regulate the formation, modification, and dissolution of
250 that keratin intermediate filaments directly regulate the morphogenesis of microridges, elongated pro
253 these data suggest that alpha3beta4* nAChRs regulate the stimulatory effects of nicotine on the mHb-
254 more, we found that c-Abl and integrin beta1 regulated the positioning of Abi1 at the leading edge.
256 of Shh activity in pMN progenitors, and also regulates the allocation of oligodendrocyte lineage cell
258 f blood vessels in the bone marrow, and also regulates the differentiation of resident mesenchymal pr
260 nce of the amino acid cysteine and that gigC regulates the expression of several genes involved in th
263 es that flagellar assembly transcriptionally regulates the production of more initial building blocks
265 ation analysis revealed that CDK8 positively regulates the transcription of several ABA-responsive ge
266 H2Bub)-Myc signaling cascade also positively regulates the transcription of the MCM6 gene that is inv
267 tically, we show a pivotal role for ESRRB in regulating the activity of ESC-specific enhancer units a
269 visiae) responds to low cytosolic iron by up-regulating the expression of iron import genes; iron imp
270 ntial requirement for LAMTOR4 and LAMTOR5 in regulating the mTORC1 pathway under fed and starved cond
271 to accumulate, indicating a role of SPAs in regulating the phyB-PIF4 module at high ambient temperat
272 osis during later developmental stages by up-regulating the pro-apoptotic genes reaper and hid The ap
273 suppressing ability of Zic1 was mediated by regulating the process of cell invasion, adhesion and ep
274 cRNA that specifically interacts with SART3, regulating the subcellular localization of the protein d
276 to identify which key mRNA and microRNAs are regulating this complex process in pathological and heal
279 transport behavior in these materials can be regulated through structural and compositional engineeri
280 al metabolism and gene expression are highly regulated to accommodate these environmental changes, in
281 way to elucidate how polar Tfp machines are regulated to coordinate multicellular movements, a conse
282 ese different components is spatiotemporally regulated to ensure efficient spindle assembly remains u
285 of higher-order DNA secondary structures to regulate transcription beyond its well-established role
286 ne-response 1 (TREE1) interacts with EIN3 to regulate transcriptional repression that leads to an inh
287 that Myo6 and the transcription factor Knot regulate transient surges of microtubule polymerization
288 rotein (FMRP) is an RNA binding protein that regulates translation and is required for normal cogniti
291 develop bone metastases, but the mechanisms regulating tumor cell dissemination from the primary sit
292 chanistically, we find that loss of the Elf5-regulated ubiquitin ligase FBXW7 ensures stabilization o
293 -associated signals converges in the NAc and regulates various aspects of reward-motivated behaviors.
294 nase (MAPK) activating death domain protein, regulates various cellular functions, such as vesicle tr
295 We also show that the circulating miR-122 regulates vascular miR-204 as miR-122 inhibition decreas
296 nt roles in human cardiovascular physiology, regulating vascular tone and smooth-muscle cell phenotyp
298 trix, but how mtDNA nucleoids are formed and regulated within cells remains incompletely resolved.
299 P(trpBA) is also dependent on tryptophan by regulating YtgR levels through a rare triple-tryptophan
300 SLC30 family and plays an essential role in regulating Zn(2+) accumulation in the insulin secretory