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1 ed the precursors of M2 macrophages, DCs and regulatory T cells.
2 tates, including multiple distinct states of regulatory T cells.
3 rtant impacts on the suppressive activity of regulatory T cells.
4 such as myeloid-derived suppressor cells and regulatory T cells.
5 ages, tumor-infiltrating dendritic cells and regulatory T cells.
6 c T-cell engager activated both effector and regulatory T cells.
7 s II-dependent fashion and are suppressed by regulatory T cells.
8 n of gut T cells and an accumulation of skin regulatory T cells.
9 ing less targeted by FOXP3(+) CD4(+) CD25(+) regulatory T cells.
10 ls and loss of intestinal forkhead box p3(+) regulatory T cells.
11 and suppression, which is mediated mainly by regulatory T cells.
12 nt and expansion of ChgA-specific peripheral regulatory T cells.
13 cells and autoimmune-protective human blood regulatory T cells.
14 he induction of therapeutic antigen-specific regulatory T cells.
15 ing of the immune response and inhibition of regulatory T cells.
16 cose metabolism because of maintenance of AT regulatory T cells.
17 ter differentiation of T helper 17 cells and regulatory T cells.
18 t was not sufficient to restore the level of regulatory T cells.
19 engraftment, including an increase in human regulatory T cells.
20 CCL2 induced formation of highly functional regulatory T cells.
21 a transcription factor which is a marker of regulatory T cells.
22 immunity, countering negative regulation by regulatory T cells.
23 ation of atheroprotective immunity involving regulatory T cells.
24 licular helper, T follicular regulatory, and regulatory T cells.
25 cytotoxic T cells and more CD25(+)/FOXP3(+) regulatory T cells.
26 ls (MDSCs) and further decreased circulating regulatory T cells.
27 sitization and anaphylaxis, while sustaining regulatory T cells.
28 necessary for the development of T(H)17 and regulatory T cells.
29 , and a decreased presence of CD4(+)Foxp3(+) regulatory T cells.
30 e deviated toward naive cells with increased regulatory T cells.
31 id cells, which then cross-regulated Th2 and regulatory T cells.
32 and CD8(+) effector T cells and in Foxp3(+) regulatory T cells.
33 , upregulated (median [interquartile range]) regulatory T cells (5.3% [3.1%-18.2%]; P < .05), reduced
34 ns suggest that immune modulators that block regulatory T cell activity may increase responses to vir
36 oportions of intestinal Foxp3(+)RORgammat(+) regulatory T cells and BALB/c mice developed increased R
37 bers correlated with increased occurrence of regulatory T cells and effector T cells and decreased na
38 immune response by inducing infiltration of regulatory T cells and expression of immune-suppressive
39 that depletes CD25-positive cells including regulatory T cells and has been approved for the treatme
40 n; numerous forkhead box protein P3 (FoxP3)+ regulatory T cells and IgG4 plasma cells; and abundant a
42 ngside PNA-specific forkhead box P3-positive regulatory T cells and IL-10(+) and TGF-beta1(+) skin-re
43 evels, but the latter preferentially induced regulatory T cells and in general downregulated T cell c
44 expression of CD3(+)/CD4(+)/CD25(+)/FoxP3(+) regulatory T cells and increased the Teff/Treg ratio.
45 cleotidases on various immune cells, such as regulatory T cells and macrophages, as well as component
48 ltration of immune-inhibitory cells, such as regulatory T cells and myeloid-derived suppressor cells,
49 tumour immune microenvironment by decreasing regulatory T cells and myeloid-derived suppressor cells.
50 The TME already shows a reduction in type 1 regulatory T cells and PD-L1+ tumor-associated macrophag
51 scribed correlations between the presence of regulatory T cells and recovery from Lyme arthritis.
55 oneal (i.p.) administration of MDP triggered regulatory T cells and the accumulation of a population
56 ited the induction of antigen-specific FoxP3 regulatory T cells and the prevention of food allergy by
59 otential by regulating macrophage functions, regulatory T cells, and secretion of proresolving mediat
60 ut neither IL-12Rbeta2 nor IL-23R, protected regulatory T cells, and suppressed Th1 and Th17 biasness
61 r function of IL-2 is to maintain functional regulatory T cells, and thus its essential function is i
62 Th2 cells, group 2 innate lymphoid cells and regulatory T cells, and to a lesser extent, on NK cells
63 tment of low HLA-DR expressing monocytes and regulatory T-cells; and transcription of immune checkpoi
64 (regs) treatment and its bystander effect on regulatory T cells are associated with CNS repair as ref
66 ell-DC interaction preferences, and discover regulatory T cells as a major T cell subtype interacting
67 responsive RORgammat-positive FOXp3-positive regulatory T cells as critical for the maintenance of to
69 nce that an elevated proportion of activated regulatory T cells at birth was specific to the sensitiz
70 ed include decreased suppressive activity of regulatory T cells at steady state, which correlates wit
74 the transcriptional adaptation trajectory of regulatory T cells between lymphoid tissue and colon.
75 as independent of antioxidant mechanisms and regulatory T cells but dependent on residential alveolar
76 TLA-4(+)) and treatment-induced depletion of regulatory T-cells (CD4(+) Foxp3(+)/CTLA-4(+)) was seen
77 eanut-specific clones in the effector versus regulatory T-cell compartment, which distinguished the c
81 atients received one of six CBMPs containing regulatory T cells, dendritic cells, or macrophages; pat
83 tive effects of propionate were abrogated in regulatory T cell-depleted angiotensin II-infused mice,
84 vitro stimulation of splenocytes from these regulatory T cell-depleted mice resulted in increases in
85 onset of autoimmune T cell activation after regulatory T cell depletion in an established model of s
89 TGF-beta activation blocks immunosuppressive regulatory T cell differentiation, which is a potential
93 ell-extrinsic factors, such as nutrients and regulatory T cells, directly and indirectly balance quie
94 nopportune induction of peripherally induced regulatory T cells during immune responses against forei
97 tively, these findings provide evidence that regulatory T cells existing at the time of, and possibly
98 spring exposed to UFPs, suggesting increased regulatory T cell expression and suppressed Th2/Th17 res
99 y two populations of tTreg, one in which the regulatory T cell fate is associated with unique propert
101 ls (p = 0.006), whereas lower proportions of regulatory T cell fractions (p = 0.009), which induce an
102 ividuals, plasma TL1A levels correlated with regulatory T cell frequencies, whereas soluble DR3 was s
104 e (CD25(+) ) forkhead box P3-positive CD4(+) regulatory T-cell frequency was lower in ALR-H-HET than
105 doleamine-2,3-dioxygenase-1 enzyme activity, regulatory T-cell frequency, activated CD38+Human Leukoc
106 ts of AIT are attributed mainly to increased regulatory T-cell function and increased allergen-specif
107 le of regulatory lymphocyte subsets, such as regulatory T cells, gammadelta regulatory T cells, NKT10
108 ubset strictly equivalent to IL-10-secreting regulatory T cells has only recently been proposed.
109 hymal stromal cells and, to a lesser extent, regulatory T cells have demonstrated efficacy in humans.
110 tion, and the induction of allergen-specific regulatory T cells, highlighting its potential use in th
111 rom the lymphoid compartment promotes a Th17/regulatory T cell imbalance and exacerbates the developm
112 aim was to investigate the role of CCR4 and regulatory T cells in cutaneous wound healing in diabeti
113 ector lymphocytes and a higher activation of regulatory T cells in grafts with subTCMR compared to cT
116 ) PD1(+) CD73(+) ICOS(+) IL-10(+) peripheral regulatory T cells in prediabetic mice, and liposome adm
118 growth, increased the ratio of cytotoxic to regulatory T cells in tumors, and prolonged survival.
119 (all CD11c-expressing cells) expands aortic regulatory T cells in vivo, limits the accumulation of T
120 y led to a reduction in AT immunosuppressive regulatory T cells, increased AT CD8(+) T cells, and no
121 Early-relapse tumors have reduced levels of regulatory T cells, increased dendritic cells (DCs), and
126 king antibody studies suggested that loss of regulatory T cells is the most important cause of aggrav
127 as well as an increase in the frequency of a regulatory T cell, known as Tr1, by week 12 of follow-up
128 were reduced natural killer cells, elevated regulatory T cells, M2-type macrophages, and high PD-L1
131 -specific immunoglobulins, T-cell cytokines, regulatory T cells, mast cells, and basophils were quant
132 kin was characterized by the accumulation of regulatory T cells, mast cells, M2 macrophages, and mark
136 e T-cell responses to interleukin (IL)-2 and regulatory T cell-mediated suppression, the composition
139 Our data suggest that the receptor CCR4 and regulatory T cells negatively affect wound healing in di
140 sets, such as regulatory T cells, gammadelta regulatory T cells, NKT10 cells, and perifollicular mast
142 tudy consortium after injection of recipient regulatory T cells, or injection of donor regulatory mon
143 sLeX(+)CD4(+)T cells exclusively contain the regulatory T cell population (CD127(low)CD25(high) and F
144 he severity of psoriasis linked to a reduced regulatory T cell population and increased IL-17A expres
147 g in the balance between proinflammatory and regulatory T cells potentially favoring a proinflammator
148 e LAMP3 + DC subgroup may be able to recruit regulatory T cells, potentially taking part in the forma
153 anistically, GM-CSF had no adverse effect on regulatory T-cell reconstitution, but linked adaptive to
155 er central memory T cell response, and lower regulatory T cell response, compared with controls.
162 Follicular regulatory T (Tfr) cells are a regulatory T cell subset that controls antibody producti
163 ies of a majority of CD4(+) conventional and regulatory T cell subsets; in general, Ag-naive subsets
164 gulatory over effector T cells, expansion of regulatory T-cell subsets expressing CXCR3 or retinoic a
165 with the presence of functional effector and regulatory T-cell subsets with diverse T-cell receptor c
167 tor expression patterns that interfered with regulatory T-cell suppression assays and were associated
169 fic CD4(+) T cells with an atheroprotective, regulatory T cell (T(reg)) phenotype in healthy individu
171 ng distinct T cell compartments, and several regulatory T cell (T(reg))-biasing anti-IL-2 antibodies
174 programs that generate a broad repertoire of regulatory T cells (T(reg) cells) able to respond to bot
182 ne receptor 4 (CCR4) is broadly expressed on regulatory T cells (T(reg)) as well as other circulating
183 Recruitment of suppressive CD4(+) FOXP3(+) regulatory T cells (T(reg)) to the tumor microenvironmen
188 neonatal Tgammadelta17 cells are innate skin regulatory T cells that are critical for skin homeostasi
189 ast in part by generation of IL-10-secreting regulatory T cells that mediate bystander immunosuppress
190 ably the retinoic orphan receptor gamma T(+) regulatory T cells, the epithelial barrier, and healthy
194 ) regulatory T cells (Treg cells) and type 1 regulatory T cells (Tr1 cells), concomitant with a reduc
196 eing evaluated for T1D is the restoration of regulatory T cell (Treg) activity, specifically directed
202 cross-sectional study aimed to determine the Regulatory T cell (Treg) properties, together with 14 pl
205 he expansion of MOG(35-55)-specific FoxP3(+) regulatory T cells (Treg cells) and type 1 regulatory T
208 ed with expansion of peripheral Foxp3CD4CD25 regulatory T cells (Treg) and increased forkhead box P3
209 athway reduced the intratumoral abundance of regulatory T cells (Treg) and the expression of the Treg
212 d detect whether the helper T cells (Th) and regulatory T cells (Treg) could affect osteoclasts and f
213 ofiles, and differing capacities to increase regulatory T cells (Treg) during coculture assays, featu
215 the latter is due to selective depletion of regulatory T cells (Treg) in a tumor microenvironment.
216 nged with Ova in vitro, though the number of regulatory T cells (Treg) in the LN remained comparable.
218 ts, with significantly reduced donor-derived regulatory T cells (Treg), increased cytotoxic effector
219 l transplantation, but they induce long-term regulatory T cells (Treg)-dependent graft acceptance onl
224 une cells including activated CD4(+)Foxp3(+) regulatory T cells (Tregs) and CD4(+)Foxp3(-) convention
225 ated with expansion of CD4(+)CD25(+)FOXP3(+) regulatory T cells (Tregs) and enhanced transforming gro
227 observed between relative counts of FOXP3(+) regulatory T cells (Tregs) and lung cancer risk, and sig
228 eatment also increases the percentage of the regulatory T cells (Tregs) and maintains immune toleranc
229 regulatory myeloid cells (Mregs) that expand regulatory T cells (Tregs) and suppress effector T cells
239 ivo and are able to increase the function of regulatory T cells (Tregs) at well-tolerated concentrati
241 for HIV cure cannot be discarded.IMPORTANCE Regulatory T cells (Tregs) can decisively contribute to
242 To test if Ag-independent stimulation of regulatory T cells (Tregs) can prevent T1D onset, groups
249 , we found that the upregulation of Foxp3(+) regulatory T cells (Tregs) in the mesothelioma tumor mic
250 for uterine tropism, we explored the role of regulatory T cells (Tregs) in the pathogenesis of Brucel
252 be-induced population of RORgamma-expressing regulatory T cells (Tregs) is essential in controlling g
253 The equilibrium of T-helper 17 (Th17) and regulatory T cells (Tregs) is often found altered in pat
254 ciated toxicity and expansion of suppressive regulatory T cells (Tregs) limit its use in patients wit
256 eous and systemic accumulation of Foxp3(+) T regulatory T cells (Tregs) partially at the expense of m
260 , functional imbalance of Th17 effectors and regulatory T cells (Tregs) promote inflammatory diseases
262 t cells, substantially increase the ratio of regulatory T cells (Tregs) to allo-activated Tconvs, and
264 mma(+) effector Th1 cells and CD4(+)Foxp3(+) regulatory T cells (Tregs) were evaluated by flow cytome
265 ition of B cell depletion to the transfer of regulatory T cells (Tregs) with indirect alloresponse fu
267 genic potential, lower frequency of Foxp3(+) regulatory T cells (Tregs), and increased number of CD8(
268 +)) T cells, CD8(+) T cells, CD4(+) T cells, regulatory T cells (Tregs), gammadelta T cells, B cells,
271 articular effector/memory subsets, including regulatory T cells (Tregs), which also displayed hardwir
283 cytometry for presence of ovalbumin-specific regulatory T cells, using activation markers, FoxP3, and
284 bset, it accounted for more than 25% of CD4+ regulatory T-cell variation and over 50% of CD8+ central
285 At birth, a higher proportion of activated regulatory T cells was associated with ST (OR = 2.89, 95
288 ge-dependent expansion of ovalbumin-specific regulatory T cells was only observed in infants who (a)
290 ed by markers associated with exhaustion and regulatory T cells, was explored by flow cytometry.
295 were significantly lower, and pro-cancerous regulatory T cells were significantly higher in Late tum
297 genic phenotype and promote the expansion of regulatory T cells, whereas no such effects are seen wit
298 ycosylated antigens also expanded functional regulatory T cells, which are necessary for the durable
299 peripheral homeostasis of Foxp3(+)Helios(+) regulatory T cells, which likely accounts for our findin