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1 onditions, the ER-mitochondria ud can play a regulatory role.
2 other tumors in which peroxynitrite plays a regulatory role.
3 REs with specific genomic repeats suggests a regulatory role.
4 hat the state of cell migration also plays a regulatory role.
5 gion, suggesting that this region may play a regulatory role.
6 ighted for an especially early and important regulatory role.
7 ng of T cells in vivo, indicating a critical regulatory role.
8 ervous system (SNS), wherein CB1 plays a key regulatory role.
9 ly unstable, and in this capacity it plays a regulatory role.
10 ibility to apoptosis underscored its central regulatory role.
11 ion pathway, potentially contributing to its regulatory role.
12 ibrosis suggests they may have unanticipated regulatory roles.
13 membrane protein cysteine residues with many regulatory roles.
14 Hippo signaling also plays important immune-regulatory roles.
15 the genome and thought to act through their regulatory roles.
16 RNAs and RNA-binding proteins with potential regulatory roles.
17 ssembling tRNA fragments and emphasize their regulatory roles.
18 ce of backtracking transitions with possible regulatory roles.
19 nderlying molecular mechanisms including its regulatory roles.
20 osphorylation at this site has an additional regulatory role and reinforcing a previously reported re
21 ory responses through dsRNA sensing and gene-regulatory roles and are controlled by the HUSH complex.
22 The core nucleosome performs a fundamental regulatory role, apart from the histone "tails," which m
24 dispensable for snRNA processing, also have regulatory roles at these protein-coding genes, possibly
25 ellular ISG15 is suggested to have an immune-regulatory role, based on disease phenotypes of ISG15-de
28 rading nonfunctional toxic proteins and play regulatory roles by targeting particular substrates in r
30 ng enzyme in polyamine catabolism, has broad regulatory roles due to near ubiquitous polyamine bindin
31 /RNA-binding protein, which plays a critical regulatory role during cell stage transitions of mouse e
32 we propose that G3BP proteins do not have a regulatory role during polyprotein processing.IMPORTANCE
33 4 residue of the 1/2 site is known to play a regulatory role during processing at this site, and we f
36 ies have suggested that dynamin also plays a regulatory role during the early stages of CME; however,
38 w that different muscle fibres have distinct regulatory roles during regeneration in the planarian Sc
40 Identifying its DNA targets is crucial given regulatory roles exerted by members of the MEF2 family a
43 likely that the CHIM will play an important regulatory role for advancing the range of Shigella vacc
46 results provide unprecedented evidence for a regulatory role for circFOXP1 as a gatekeeper of pivotal
47 In summary, these studies present a novel regulatory role for Crth2 during inflammatory response i
50 s had reduced TGFbeta signaling, revealing a regulatory role for embryonic myosin in the TGFbeta sign
51 reticulocyte yields, suggesting an important regulatory role for EMP3 in erythropoiesis and control o
53 Overall, these results establish a novel regulatory role for histone H3 acetylation during the in
54 L33-ILC2-IL5-neutrophil axis defines a novel regulatory role for ILC2 in acute lung injury that could
56 ever, some studies have suggested a positive regulatory role for NLRX1 in inducing antiviral response
57 These empirical results suggest a plausible regulatory role for NnCYP76B6 in CPT biosynthesis and al
60 n protein dephosphorylation, revealing a new regulatory role for phosphorylation/dephosphorylation cy
63 ollectively, these results demonstrate a new regulatory role for SLX4IP in maintaining an efficient S
64 than wild-type littermates, which suggests a regulatory role for testicular phosphate and calcium hom
65 Taken together, our studies support a key regulatory role for the fractalkine axis in advanced and
66 Taken together, these findings outline a regulatory role for the GPR146/ERK axis in systemic chol
68 ken together, our results indicate a pivotal regulatory role for the SphK1/S1P axis in maintaining th
70 of ZMP/SZMP and ATP, revealing a much wider regulatory role for these intermediate metabolites in an
78 mtDNA could be further elevated, suggesting regulatory roles for 6mA in mitochondrial stress respons
79 revealed additional B12-binding enzymes and regulatory roles for B12 Here we report the development
80 differentiation in the field and suggest key regulatory roles for clinical factors and gdv1 in gameto
84 ted to directly control gene regulation, but regulatory roles for ribosomal RNA (rRNA) remain largely
86 ty for each construct, we uncovered new auto-regulatory roles for the ubiquitin binding domains and t
87 tral role of NAD in plant metabolism and its regulatory role have been investigated extensively at th
88 lular GABA concentration [GABA] could play a regulatory role here, we use a GABA 'sniffer' patch in a
91 tophagy in the developing mouse lung and its regulatory role in airway branching and terminal sacculi
92 The tumor microenvironment plays a critical regulatory role in cancer progression, especially in cen
94 rs and mutants, provided insights into their regulatory role in defined modules of the JA network.
95 sociating domains (TADs) was shown to have a regulatory role in development and cellular function, bu
97 er, the molecular mechanisms underlying ER's regulatory role in endometrial cancer are poorly underst
98 rs of microRNA-200 (miRNA-200) family have a regulatory role in epithelial to mesenchymal transition
99 , it is not clear whether ECRs play a direct regulatory role in G-protein signaling or simply serve a
100 e architecture is thought to play a critical regulatory role in gene expression, but the mechanisms g
102 -derived extracellular vesicles (EVs) play a regulatory role in hematopoiesis and have been shown to
103 function focused on the nervous system, its regulatory role in hematopoiesis has not been reported.
105 e to nutrient limitation, plays an important regulatory role in lipid homeostasis upon energy demands
106 ntified an lncRNA that can play an important regulatory role in liver function and provide new insigh
107 crophages by ER stress, and VDR plays a dual regulatory role in macrophages by protecting against ER
108 is not known whether the CTD takes an active regulatory role in metal recognition and discrimination
111 ation (APA) plays a key post-transcriptional regulatory role in mRNA stability and functions in eukar
112 lude that nucleoporins play an unanticipated regulatory role in NEBD, by recruiting PLK-1 to the NE t
114 d that MKK7-JNK signaling plays an important regulatory role in neural development, however, post-dev
115 sults suggest that RN-tre plays an important regulatory role in NMII RLC distribution, phosphorylatio
116 e two distinct endodermal barriers and their regulatory role in nutrient transport is still limited.
118 t dynamic RNA methylation plays an important regulatory role in oligodendrocyte development and CNS m
119 of alphaBSer-59, known to play an important regulatory role in oligomerization, was severely inhibit
120 mmary, our data suggest that CytM may have a regulatory role in photomixotrophy by modulating the pho
121 ight and in the dark, suggesting a potential regulatory role in photosynthesis, but this has not been
122 increasingly recognized to play an important regulatory role in post-transcriptional gene regulation.
124 s integrin-dependent cell migration, but its regulatory role in skin dendritic cells (DCs) during inf
127 in the mediation of autophagy; however, its regulatory role in the autophagic process remains contro
130 s suggest the Sts proteins play an important regulatory role in the host response to bacterial infect
132 and DNA binding), S. suis 2 retains a single regulatory role in the modulation of NAD(+) salvage.
133 show that the PDK2-lactic acid axis plays a regulatory role in the observed metabolic imbalance and
135 ng that mechanical forces may play a broader regulatory role in translation than previously appreciat
136 other findings suggest that CLP1/cbc plays a regulatory role in tRNA splicing by serving as a negativ
137 udy to demonstrate that uterine PVAT plays a regulatory role in UtBF, at least in part, as a result o
139 r Ser78 in the T78S mutant) plays a negative regulatory role in vivo and provides an explanation for
142 to pancreatic cancer progression through its regulatory roles in both tumor cells and the tumor micro
143 S family of adaptor proteins, with important regulatory roles in cell migration, cell cycle control,
144 ylation is an epigenetic mark with important regulatory roles in cellular identity and can be quantif
145 owth and metastasis, may also have important regulatory roles in controlling the tumor microenvironme
146 stinct from RBP-P, RBP-L exhibits additional regulatory roles in development, either directly through
147 The ECM serves important structural and regulatory roles in establishing tissue architecture and
148 plays important but still poorly understood regulatory roles in eukaryotic cells, including as a sig
150 a current view of the enteric glia and their regulatory roles in gastrointestinal (GI) (patho)physiol
151 As) have been demonstrated to play important regulatory roles in gene expression, from histone modifi
156 Fibrinogen is a complex glycoprotein with regulatory roles in hemostasis, tumor development, wound
157 from rice (Oryza sativa), and unravel their regulatory roles in key steps of reproductive developmen
160 RNAs) are small noncoding RNAs with profound regulatory roles in many areas of biology, including can
161 MA is growing due to its recently identified regulatory roles in metabolism, differentiation, cell cy
162 hypothesize that the circadian system plays regulatory roles in minimizing the IR-induced cardiotoxi
163 ion of 5'TOP mRNAs are controversial and its regulatory roles in mTORC1-mediated translation remain u
164 of small noncoding RNAs that have important regulatory roles in multicellular organisms including in
166 t trehalose and trehalose 6-P play important regulatory roles in nectary starch degradation and necta
167 discovered in animals and plants, and their regulatory roles in numerous biological processes have b
169 nct ribosomal protein (RP) stoichiometry and regulatory roles in protein synthesis has been speculate
175 organelles, implying that they may have key regulatory roles in the biophysical assembly process.
176 two signaling molecules that have important regulatory roles in the development and plasticity of ne
177 cyclin-dependent kinases (CDK) had critical regulatory roles in the expression and chromatin activat
178 croRNAs have demonstrated critical and broad regulatory roles in the pathogenesis of PH via the direc
179 s evidence for better understanding of miRNA regulatory roles in the process of fiber development, wh
182 s transcriptomes, which could play important regulatory roles in translation and other biological pro
183 rent muscle types have distinct and specific regulatory roles in wound signalling and patterning to e
184 generally not thought to play a significant regulatory role, in fact impart restrictions on the deve
185 evealed the potential molecular profiles and regulatory roles involving the TL difference between NSE
187 previously unknown structural, functional or regulatory roles, not apparent from systematic point mut
188 nknown cannabinoid receptor 2 (CB2)-mediated regulatory role of 2-AG on IFN-alpha induction by pDCs.
189 el in Arabidopsis (Arabidopsis thaliana) the regulatory role of ABA in mechanisms that determine root
192 f holo-ACPP in the cell identify a potential regulatory role of ACPS in fatty acid biosynthesis.
193 These results provide new insights into the regulatory role of adherens junctions in initiating and
194 enhanced cell death, which confirmed the key regulatory role of Ca2+ in EPEC-induced pyroptosis.
196 in living cells and elucidates the essential regulatory role of CK1e in DVL conformational dynamics.
199 ion addition, including Zn(2+), suggesting a regulatory role of divalent cations in tubule formation.
202 Gene silencing approaches confirmed the regulatory role of HIF-1alpha in BACE1-AS/BACE1 in Tat-m
203 3D angiogenesis model demonstrated the dual regulatory role of high-sulfated derivatives on the biol
205 try and replication and highlight a positive regulatory role of IFN-induced proteins in HIV-1 infecti
206 specific conformations of an enzyme, but the regulatory role of IMPDH filaments has remained unclear.
207 drial ATP production, demonstrating a direct regulatory role of insulin on brain mitochondrial functi
211 we aimed to improve our understanding of the regulatory role of lncRNA KCNQ1OT1 during osteoblast pro
212 vances regarding both the pathogenic and the regulatory role of lymphocytes in SLE beyond the product
213 es a comprehensive overview of the important regulatory role of methylation in metastatic castration-
215 This is the first study demonstrating a regulatory role of miR-485-5p for multiple UGT2B enzymes
219 xic induction of SLC2A3, indicating a direct regulatory role of NICI in SLC2A3 expression, which was
224 thrombin production in PRP, underlining the regulatory role of PN-1 released from platelet granules.
225 roximal ribosome binding sites, suggesting a regulatory role of processing on translation initiation.
226 ults of our study not only shed light on the regulatory role of RPTP-D2 domains, but also provide a p
228 ain kinase (MLCK) expression, confirming the regulatory role of TAK-1 and NF-kappaB p65/p50 in up-reg
232 Among the three tRNA binding sites, the regulatory role of the exit (E) site, where deacylated t
233 h tRNA gene activity, supporting a prominent regulatory role of the local genomic context in combinat
240 Together, these data indicate a fundamental regulatory role of the VDR in the regulation of myogenes
241 eriments can be performed to investigate the regulatory role of thousands of oligonucleotide sequence
244 es provided unambiguous understanding of the regulatory role of WsMYC2 in context to withanolides and
245 block, These findings confirm the important regulatory roles of AlucJHEH in A. lucorum and indicate
249 Altogether, our results elucidate positive regulatory roles of CaMPK9 and CaWRKY40 in modulating de
250 results illuminate previously unappreciated regulatory roles of DNA cleavage activity on Cas9's conf
251 In the present study, we characterized the regulatory roles of five BRC gene members in tobacco (Ni
253 tive small-molecule inhibitors to assess the regulatory roles of interleukin-1 receptor (IL-1R)-assoc
257 RNA transfer and add multiple layers to the regulatory roles of miRNAs and PMPs in tumor progression
260 environmentally regulated, architectural and regulatory roles of nucleoid-associated proteins and the
261 emerging research indicates that the immune regulatory roles of platelets may be just as important.
265 R, we sought to investigate specifically the regulatory roles of the beta-arrestin2 isoform on expres
271 Our data suggest that rare codons have a regulatory role only if they are present within appropri
273 AP2 transcription factors may play a limited regulatory role, perhaps operating in conjunction with e
274 ocess during cutaneous wound healing and the regulatory roles played by catecholamines during the pro
275 tly extends the current understanding of the regulatory roles played by dynamin isoforms during early
277 Taken together, our study reveals dynamic regulatory roles played by neurogranin on synaptic plast
279 lude upstream ORFs that are likely to have a regulatory role, several in-frame internal ORFs within e
283 ntial behavior, potentially highlighting the regulatory role that this domain may play in the two ant
284 These findings, along with the well-known regulatory roles that SIRT1 plays in modulating both ana
285 ptic active zone (AZ) proteins have multiple regulatory roles that vary during distinct stages of neu
286 intensified research into the pathogenic and regulatory roles these cells play in demyelinating disea
288 hese regions play a variety of signaling and regulatory roles, they appear to be rapidly evolving at
290 ar sarcomeric protein playing structural and regulatory roles through its dynamic interaction with ac
291 pathway of Mei2 turnover, but rather plays a regulatory role to limit its accumulation or inhibit its
292 2 functions in a noncanonical/non-cell cycle regulatory role to maintain adult pyramidal neuron ribos
293 or antiviral functions, PTMs generally play regulatory roles to tune protein functions, levels, and
294 nsient over-expression displayed significant regulatory role vis-a-vis withanolides and stigmasterol
295 ation between an i-modulon and sigmaS, whose regulatory role was previously undefined; 3) the regulat
296 findings that E2F3a and E2F3b have divergent regulatory roles, we set out to study the putative trans
297 -GMP specified by these enzymes has a global regulatory role, with about 20% of all S. venezuelae gen
300 ined immune-cell subsets can play key immune-regulatory roles, yet their detailed study is often hamp