ライフサイエンスコーパス: regulatory system

1 a-subunit through the ferredoxin-thioredoxin regulatory system.

2 1, while highlighting the complexity of this regulatory system.

3 iated motility is repressed by the PhoP/PhoQ regulatory system.

4 function or perturbations in the Wnt5a-Sfrp5 regulatory system.

5 ge that prompts reassessment of this classic regulatory system.

6 r-independent mechanism involving the RsmAYZ regulatory system.

7 ng the response regulator of a two-component regulatory system.

8 omponent responder (CovR)/sensor (CovS) gene regulatory system.

9 on in yycG, a component of the WalKR sensory regulatory system.

10 flagella through the ExoS/ChvI two-component regulatory system.

11 imate the state of a model of the sleep-wake regulatory system.

12 nd misregulation of the cell-autonomous iron regulatory system.

13 e by sketching possible ways forward for the regulatory system.

14 ly controlled by the EnvZ/OmpR two-component regulatory system.

15 omal function for uS12/Rps23 central to this regulatory system.

16 omponent of the fungal ambient pH-responsive regulatory system.

17 stinal mucus, a bacterial toxin, and a toxin regulatory system.

18 ut2) neurons as a key node of the wake-sleep regulatory system.

19 ion were governed by the SrrAB two-component regulatory system.

20 entations of rhythms of multiple homeostatic regulatory systems.

21 al processes are still controlled by ancient regulatory systems.

22 luence organismal aging by affecting various regulatory systems.

23 the general properties of post-translational regulatory systems.

24 bias as an evolutionary driver in other cis-regulatory systems.

25 involve sophisticated genetic and epigenetic regulatory systems.

26 en may signal the degradation of body weight regulatory systems.

27 e expression by the DevRS/DosT and NarL/NarS regulatory systems.

28 ntain their homeostasis by multiple feedback regulatory systems.

29 increasing the robustness and plasticity of regulatory systems.

30 both protein expression and various cellular regulatory systems.

31 eptual framework for evolution of biological regulatory systems.

32 t well suited for a wide class of biological regulatory systems.

33 hich may compromise approach, avoidance, and regulatory systems.

34 n host, in part through its 16 two-component regulatory systems.

35 g gene functions and for engineering genetic regulatory systems.

36 erty-health relations by influencing emotion regulatory systems.

37 tress, causing wear and tear across multiple regulatory systems.

38 understanding of pathways and other complex regulatory systems.

39 th those seen in hypothalamic energy balance-regulatory systems.

40 to the workings of these complex eubacterial regulatory systems.

41 n in a manner similar to that by lantibiotic regulatory systems.

42 equires the contributions of both individual regulatory systems.

43 and neurologic significance of neuronal RNA regulatory systems.

44 used to describe allostery in two-component regulatory systems.

45 ple Michaelis-Menten type proteomic and gene regulatory systems.

46 evolutionary changes and shape developmental regulatory systems.

47 environment through the use of two-component regulatory systems.

48 use may benefit from targeting cytoskeletal regulatory systems.

49 bin formation, and perturbation of erythroid regulatory systems.

50 er, illustrating homeostatic behavior of DSB regulatory systems.

51 ential steps requiring several two-component regulatory systems.

52 ere, we investigated the role of 2-component regulatory systems (2CSs) in plague because the latter a

53 phosphate pst transporter and the phoB-phoR regulatory system, a high-affinity ammonium amtB transpo

54 containing a deletion of the accessory gene regulatory system (Agr), wherein both strains have signi

55 With the right changes to legal and regulatory systems, algorithms can thus potentially make

56 This type of regulatory system allows cooperating populations to resp

57 response regulators from other two-component regulatory systems, although a sensor for the system has

58 the end, this review will shed light on how regulatory systems, although seemingly conserved among b

59 dentified changes in the YxdJK two-component regulatory system and a putative fatty acid kinase (dak)

60 The MARS complex may be part of a cellular regulatory system and a target for drug development.

61 ption factor that is part of a developmental regulatory system and a ureteric bud marker.

62 -bp deletion in the fasC gene of the fasBCAX regulatory system and an inactivating polymorphism in th

63 ve research and implementation involving the regulatory system and clinical community could substanti

64 uted to the structure of the transcriptional regulatory system and could therefore be a common featur

65 DNA damage response takes advantage of this regulatory system and heavily relies on ubiquitin-based

66 oadens the genes controlled by the flagellar regulatory system and implicates this system in co-ordin

67 signaling network and the histone-based gene regulatory system and propose an integrated regulatory s

68 n in synovial fluid, low activity of the Agr regulatory system and subsequent low production of the p

69 hus far the origin and evolution of both the regulatory system and SXL protein's sex-determination fu

70 of mHtt into IBs is policed by the RQC-Hsf1 regulatory system and that such compartmentalization, ra

71 nal and mechanistic details of the plant PUF regulatory system and the biological relevance of the TE

72 ic variants as potential perturbants of gene regulatory system and to recover gene networks via analy

73 ng, group moralities reflect these different regulatory systems and emphasize social coordination thr

74 As understanding of bacterial regulatory systems and pathogenesis continues to increas

75 ween the emergence and expansion of microRNA regulatory systems and the evolution of complex multicel

76 y cellular stress are key components of this regulatory system, and further adaptation of the metabol

77 e exopolysaccharide/quorum sensing ExpR/SinI regulatory system, and posttranslational regulation seem

78 regulated by the GAS CovR-CovS two-component regulatory system, and we demonstrated that bacteria wit

79 lacked genes that encode known two-component regulatory systems, and antimicrobial production and res

80 Cells with an intact complement negative regulatory system are protected from complement attack,

81 ith mutations in the CovR-CovS two-component regulatory system are selected for during localized GAS

82 The clinical implications of this novel regulatory system are shown as miR-515-5p is significant

83 d the importance of the PhoP/Q two-component regulatory system are similar to what has been shown in

84 Although several aspects of this regulatory system are well understood, no BirA superrepr

85 Many environmental signals and regulatory systems are integrated into this circuit to p

86 ology of neurodegeneration and how different regulatory systems are interconnected through a central

87 Several regulatory systems are known to control acid resistance

88 Cellular metabolic and regulatory systems are of fundamental interest to biolog

89 hile simultaneously ensuring that these gene regulatory systems are robust to perturbation.

90 fectual means used by cells to control these regulatory systems are sulfur-based redox switches, whic

91 Here we describe an autogenous transgene regulatory system (ARES), based on the bacterial lac rep

92 the urinary tract and implicate the c-di-GMP regulatory system as an important factor in the persiste

93 d dimensional capacity in different top-down regulatory systems associated with ADHD and CD symptoms.

94 ts that the PmrAB TCS controls expression of regulatory systems associated with the production of add

95 lts suggest that the mbd cluster recruited a regulatory system based on the MbdR regulator and its ta

96 sion system in zebrafish and the gene-switch regulatory system based on the pGL-VP chimeric regulator

97 Here, we evaluate cell-free regulatory systems based on T7 promoter-driven expressio

98 ive strategy is achieved via a two-component regulatory system (BceRS) working in a sensory complex w

99 andom Forest (iJRF), which characterizes the regulatory system between miRNAs and mRNAs using a netwo

100 sors silence particular enhancers within cis-regulatory systems, blocking their expression throughout

101 sis involves the CrsR-CrsA partner-switching regulatory system, but the exact mechanism by which CrsR

102 f public hospitals, and institute a stronger regulatory system, but these changes have been slowed by

103 Their master regulatory system BvgAS controls expression of at least

104 nchiseptica rely on the global two-component regulatory system BvgAS to control expression of distinc

105 ltaneously decodes the perturbations of gene regulatory system by a large number of SNPs to identify

106 ng to the local cell-population density in a regulatory system called quorum sensing.

107 Because activation of either regulatory system can compensate for failure of the othe

108 Alterations of this Pol IV-based regulatory system can generate potentially desirable and

109 Together, our results show that several regulatory systems can independently affect energy organ

110 criptional regulator/noncoding RNA virulence regulatory system, capable of causing S. aureus bloodstr

111 ic balancing, enhancing respiration, dynamic regulatory systems, chromosomal engineering, decoupling

112 g peptide (CSP), via a classic two-component regulatory system ComDE.

113 The putative two-component regulatory system composed of EepR and EepS regulates he

114 tein) and CV2 (crossveinless-2) would form a regulatory system consisting of negative feedback loops

115 for signal transduction is the two-component regulatory system, consisting of a sensor kinase (usuall

116 nd broadly conserved WalR-WalK two component regulatory system continuously monitors changes in the a

117 sensor kinase (LiaS) of a poorly defined GAS regulatory system contributes to a carrier phenotype thr

118 provide insight, here we investigate the cis-regulatory system controlling brinker (brk) expression i

119 The regulatory system controlling cyclin C-Med13p interactio

120 Collectively, our findings establish a regulatory system controlling developmentally deposited

121 ns that constitute a previously unrecognized regulatory system controlling spread of IncI1 plasmids.

122 comprehensive picture of the transcriptional regulatory systems controlling periodic gene expression

123 The PhoPQ two-component regulatory system coordinates the response of Salmonella

124 algesia include activation of bimodal opioid regulatory systems, counter-regulatory mechanisms, neuro

125 the ecology of the community, by the role of regulatory systems coupled to the environmental conditio

126 is negatively regulated by the two-component regulatory system CovR/S.

127 ophils select mutations in the two-component regulatory system CovRS of group A Streptococcus (GAS) d

128 reptococcus (GAS) can have a mutation in the regulatory system CovRS, and this mutation can render st

129 responder (R)/sensor (S) two-component gene regulatory system (covRS), which enhances the virulence

130 cular underpinnings of a fructose metabolism regulatory system crucial for pathological growth.

131 n of mutational effects of a transcriptional regulatory system differs from the distributions of its

132 Plant-microbe interactions involve numerous regulatory systems essential for plant defense against p

133 imal complexity, but it is unclear when this regulatory system evolved.

134 Humans' circadian, circannual, and metabolic regulatory systems evolved to be adaptive in environment

135 This regulatory system exerts combinatorial control not only

136 ese results suggest that multiple sleep-wake regulatory systems exist in a brain region-specific mann

137 1157 DmdB enzymes, suggesting that a complex regulatory system exists in marine bacteria.

138 where DYNLL1 and CHICA-HMMR form part of the regulatory system feeding back spindle position to dynei

139 The reliance on this biochemical regulatory system for "exercising" synapses is reminisce

140 we describe a non-canonical, AGGF1-mediated regulatory system for endoplasmic reticulum stress signa

141 The UK self-regulatory system for exposing marketing violations reli

142 A key regulatory system for protein stability is given by the

143 onserved repeated sequences suggesting novel regulatory systems for both transcription and translatio

144 Both pathogens and hosts have complex regulatory systems for metal homeostasis.

145 icity is retained in classical two-component regulatory systems from this organism.

146 This work identifies a new transcriptional regulatory system governing the ability of S. pyogenes t

147 represent a previously unidentified internal regulatory system governing the establishment of adaptiv

148 Staphylococcus aureus uses the two-component regulatory system GraRS to sense and respond to host def

149 The two-component regulatory system, GraRS, appears to be involved in stap

150 The Staphylococcus aureus two-component regulatory system, GraRS, is involved in resistance to k

151 In this study, we identified a two-component regulatory system GrvRS as the main regulator of ace exp

152 It appears that the cyclic-AMP-CRP regulatory system has been adapted to respond to distinc

153 The Cpx two-component regulatory system has been shown in Escherichia coli to

154 that, to preserve function, an entire redox regulatory system has to be retained within its original

155 Several regulatory systems have been described to govern the ini

156 inducer in vivo, suggests that this type of regulatory system holds great promise for applications i

157 ca was also dependent on the BvgAS virulence regulatory system; however, in contrast to the case in B

158 o assess similarities with the known hormone regulatory system in Arabidopsis.

159 a comprehensive characterization of the gene regulatory system in each subpopulation.

160 The goal was to investigate this regulatory system in endothelial differentiation and vas

161 r results suggest a role of the miR858-MYB83 regulatory system in finely balancing gene expression pa

162 new information about this poorly described regulatory system in GAS.

163 ple, we established an orthogonal epigenetic regulatory system in mammalian cells using N6-methyladen

164 peroxiredoxins (Prxs) comprises a key redox regulatory system in mammalian cells.

165 gnaling, suggesting a universal role of this regulatory system in multiple pathways in Drosophila.

166 fic mutations in the GacS/GacA two-component regulatory system in swarming colonies of Pseudomonas pr

167 ined helices, is a key component of the iron regulatory system in the brain and thus is widely recogn

168 Perturbation of this regulatory system in the brain may contribute to the dev

169 argument that eCB signaling is an important regulatory system in the brain that largely functions to

170 xistence of an evolutionarily conserved gene regulatory system in the bundle sheath.

171 ion of the Y. pestis PhoP-PhoQ two-component regulatory system in the flea.

172 el to implement comparable recombination and regulatory systems in other bacteria.

173 the advantage of characterizing multi-switch regulatory systems in terms of their constituent switche

174 mechanisms and their interactions with other regulatory systems in the control of keratinocyte differ

175 hese results highlight the importance of the regulatory systems in the evolution and adaptation of ba

176 To determine whether cytoskeletal regulatory systems in the oPFC influenced decision-makin

177 ere, we explore the potential of elucidating regulatory systems in varied cell types using computatio

178 -28 as an example to illustrate how distinct regulatory systems, including miRNAs and multiple protei

179 es much of the known biochemistry of the IDH regulatory system into a single quantitative framework a

180 the ventral tissue are integral parts of the regulatory system involved in the development of HSCs.

181 The GBL regulatory system involves a small, and not completely d

182 Thus, MCV has evolved a regulatory system involving SCF(Fbw7) that controls vira

183 In summary, our results show a complex regulatory system involving TP53, KRAS, and let-7a.

184 ation threshold, the AgrC-AgrA two-component regulatory system is activated through a cascade of phos

185 We infer that the vertebrate Hox bipartite regulatory system is an evolutionary novelty generated b

186 The Gac/Csr regulatory system is conserved throughout the gamma-prot

187 The biological regulatory system is highly dynamic.

188 We find that the regulatory system is highly robust to variations in cofa

189 cate that while full activation of the BvgAS regulatory system is required for colonization and sever

190 we demonstrate that the phoPR two-component regulatory system is required to slow Mtb growth at acid

191 The core of this regulatory system is the PhyR protein, which contains a

192 re we investigate two levels at which the pH regulatory system is transcriptionally moderated by pH a

193 The importance of this complex regulatory system is underscored by the identification o

194 m that involves the Csr and BarA/UvrY global regulatory systems is exposed.

195 e transcription of gonococcal ompA through a regulatory system known to be important for survival of

196 n explore different approaches for composing regulatory systems, leading to the implementation of ind

197 At the heart of this regulatory system lies a class of specialized protein qu

198 ellular anion fluxes, and unveils a possible regulatory system linking PT growth modulation by pH, GA

199 sensory system that we refer to as the LytTR Regulatory System (LRS).

200 This regulatory system may represent a mechanism by which aux

201 In X. campestris, a regulatory system mediated by the signal molecule DSF co

202 Hence, a conserved WUS/WOX-CLV regulatory system might control cell proliferation and d

203 thetic refactoring makes naturally occurring regulatory systems more amenable to manipulation by remo

204 Vibrio cholerae's CarRS two-component regulatory system negatively regulates expression of vps

205 been studied as a paradigmatic two-component regulatory system not only to dissect structural and fun

206 creasing evidence that perturbations in this regulatory system occur in the hypertrophied and failing

207 eractions can achieve an emergent and robust regulatory system of collective foraging activity in ant

208 arises in the isocitrate dehydrogenase (IDH) regulatory system of Escherichia coli, which was shown i

209 ox gradient, which is interpreted by the cis-regulatory system of the nodal gene to cause its express

210 Novel relationships, common to the regulatory systems of all endotherms, are found to relat

211 o function broadly within the signalling and regulatory systems of the cell.

212 dly acidic pH activates the master virulence regulatory system PhoP/PhoQ in the facultative intracell

213 ssrB is necessary to activate the ancestral regulatory system PhoP/PhoQ of Salmonella enterica serov

214 Genes controlled by the two-component regulatory system PhoPQ modify lipopolysaccharides.

215 g aerobic nitrate metabolism, the DevRS/DosT regulatory system plays a primary role that is augmented

216 ostasis, emulating the role of the CusR/CusS regulatory system present in other enteric bacteria.

217 The Set2-Rpd3 regulatory system prevents cryptic promoter function wit

218 e architecture of the ICEMlSym(R7A) transfer regulatory system provides an example of how a set of mo

219 The CI regulatory system provides an intriguing comparison with

220 This unique acid-activated regulatory system provides insights into an evolutionary

221 This natural auto-regulatory system provides the basis for engineering IL-

222 a structural feature common to many cellular regulatory systems: regulators are typically either boun

223 Two-component regulatory systems represent potential therapeutic targe

224 y highlighting how sRNAs converge with known regulatory systems required for biofilm formation.

225 This regulatory system requires TFL1 expression to rise in pr

226 dules of this phosphorylation-based temporal regulatory system results in CCP maturation being delaye

227 odel microbial community is dependent on the regulatory system's influence on the distribution of dis

228 system as a spatiotemporally controlled gene regulatory system, several approaches of conditional act

229 based on experimental perturbations of gene regulatory systems such as gene knock-out experiments, f

230 es are most often regulated by two-component regulatory systems such as the EnvZ/OmpR system, which r

231 daptation is often mediated by two-component regulatory systems, such as the PhoP/PhoQ system that re

232 Specific key regulatory systems susceptible to programming may influe

233 gulated, in part, by the SrrAB two-component regulatory system (TCRS).

234 Shigella flexneri two-component regulatory systems (TCRS) are responsible for sensing ch

235 ic levels of metals, including two-component regulatory systems (TCRS).

236 systems that are composed of a two-component regulatory system (TCS) and an ATP-binding cassette (ABC

237 ens coordinate virulence using two-component regulatory systems (TCS).

238 Two-component gene regulatory systems (TCSs) are a major mechanism by which

239 In bacterial two-component regulatory systems (TCSs), dephosphorylation of phosphor

240 a central or peripheral role for BKs in the regulatory system that controls adipose tissue and weigh

241 Csr is a conserved global regulatory system that controls expression of several hu

242 r results establish that PmrAB is the global regulatory system that controls lipopolysaccharide modif

243 atomic scale, of a conserved transcriptional regulatory system that controls the cellular and infecti

244 d that BMP2K isoforms constitute a BMP2K-L/S regulatory system that controls the distribution of SEC1

245 Many elements of the regulatory system that controls this process are known,

246 These factors appear to be part of a regulatory system that enables concerted expression of t

247 kinase-mediated ER-PM cross-talk comprises a regulatory system that ensures cellular integrity under

248 A regulatory system that integrates science and welfare is

249 we provide a complementary analysis of this regulatory system that investigates the roles of both De

250 are regulated by the PhoR/PhoB two-component regulatory system that is used to sense and respond to P

251 opsis has a highly intricate transcriptional regulatory system that may allow for the optimization of

252 S. aureus AirSR is a redox-dependent global regulatory system that plays important roles in gene reg

253 CarRS is a two-component regulatory system that positively regulates almEFG expre

254 Finally, PTMs form a multidimensional regulatory system that provides the speed and flexibilit

255 We modeled our results to propose a regulatory system that transmits signals from differenti

256 Today, we are faced with a regulatory system that, weakened by decades of limited r

257 tory control primarily through two-component regulatory systems that allow for sensing and responding

258 tivating mutations within genes encoding two regulatory systems that control the expression of import

259 The regulatory systems that control the synthesis and regene

260 oordination of diverse cytological events by regulatory systems that drive the cell from mitosis into

261 tissues exhibit striking similarities in the regulatory systems that establish gene expression patter

262 dels: first, the combinatorial, hierarchical regulatory systems that generate the orderly, synchroniz

263 preliminary insight into the adipose tissue regulatory systems that may contribute to the physiologi

264 n rhythmicity, therefore bridging two global regulatory systems that modulate all aspects of bodily f

265 at includes the hptRS (a novel two-component regulatory system), the hptA (a putative phosphate senso

266 Despite the importance of this fine regulatory system, the molecular mechanisms underlying t

267 potential regulatory mechanisms of a global regulatory system, the well-studied carbon storage regul

268 evidence for the emergence of an epigenetic regulatory system through recruitment of selfish element

269 gher organism develops a complex translation regulatory system to achieve accurate and flexible gene

270 lusion, BAG and URX neurons work as a neural-regulatory system to counterbalance each other via diffe

271 s to explain the contribution of the Crc/Hfq regulatory system to evolutionary fitness of pseudomonad

272 nd Typhimurium, have evolved a two-component regulatory system to exist inside Salmonella-containing

273 he glucose transporter GLUT4 as a glycolytic regulatory system to meet the activity-driven increase i

274 omplexes are important, and that allows this regulatory system to respond rapidly to change in cellul

275 nd subsequently interacts with the VirA/VirG regulatory system to stimulate virulence (vir) gene expr

276 red with the number of bacterial genomes and regulatory systems to be discovered.

277 Bacteria utilize multiple regulatory systems to modulate gene expression in respon

278 days, a period thought to be sufficient for regulatory systems to respond to the overconsumption of

279 gnal transduction by classical two-component regulatory systems typically entails an intermolecular p

280 , the HPT system consists of a two-component regulatory system (UhpAB) and a phosphate sensor protein

281 The flagellar regulatory system ultimately influences sigma(28) activi

282 Pushing the boundaries of the regulatory system unveils a genetic hyperstress program

283 is instrumental in interrogating eukaryotic regulatory systems using heterogeneous data.

284 studying specific, experimentally tractable regulatory systems using the tools of modern systems bio

285 ible require the action of the two-component regulatory system VanSR to induce expression of resistan

286 inylation of lipopolysaccharides and related regulatory systems, was down-regulated in host-like medi

287 erential equation model for a single genetic regulatory system, we examine the dynamical effects of n

288 ion of the P. aeruginosa AlgZR two-component regulatory system were examined.

289 of pilus expression, and two-component gene regulatory systems were shown to affect the bacterial ph

290 t system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-

291 posed when PrEP was not approved through the regulatory system, which could have affected uptake; and

292 ntiporters, represent a carefully tuned self-regulatory system, which drives the cytoplasmic pH back

293 pH and CAMP through the PhoPQ two-component regulatory system, which stimulates lipid A remodeling,

294 Csr is a conserved global regulatory system, which uses the sequence-specific RNA-

295 the gacA/gacS bacterial two-component global regulatory system while leaving the plasmid sequence int

296 ata has been confirmed in inferring how gene regulatory systems will respond under various conditions

297 Saccharomyces cerevisiae HO gene is a model regulatory system with complex transcriptional regulatio

298 of E. coli respond by activating the TorTSR regulatory system with consequent induction of TMAO redu

299 An elaborate regulatory system within cells, the protein homeostasis

300 Thus, this universal regulatory system within the NPC is crucial to control l