ライフサイエンスコーパス: relief of

1 Immediate pain relief of 100% was achieved in all patients.

2 r exposure to C. parvum, which resulted in a relief of 3' untranslated region-mediated translational

3 ly activated p21 gene expression, suggesting relief of a corepressor function dependent on both prote

4 udy uncovers a novel function of TNKS in the relief of a feedback loop induced by MEK inhibition on F

5 l redistribution of RNAP that may facilitate relief of a metabolic bottleneck to growth.

6 sion of a constitutively active PI3K or (ii) relief of a negative feedback loop on PI3K by prolonged

7 dependent export does not simply reflect the relief of a nuclear retention mechanism.

8 es that stenting achieves superior immediate relief of a relevant pressure gradient compared with bal

9 rints encode information only in the surface relief of a single polymeric material, nanoscale 3D prin

10 Galphaz-null islets appears to be due to the relief of a tonic inhibition of adenylyl cyclase, as cAM

11 ed short-acting beta2-agonists provide rapid relief of acute symptoms, but maintenance with daily inh

12 prevalence of herbal treatment usage for the relief of allergic rhinitis symptoms in Turkey.

13 l separation is stimulated by the reversible relief of amidase autoinhibition governed by conserved s

14 ivity to increase NADP(+) production through relief of an autoinhibitory function inherent to its ami

15 beta2-agonists: a decrease likely caused by relief of an intra-acinar airway obstruction that we pro

16 obstruction due to FM, providing significant relief of anatomic obstruction and sustained clinical im

17 ensatory hypertrophy, and improves following relief of aortic constriction.

18 stent is safe and associated with persistent relief of aortic obstruction.

19 in a subset of prostate cancer cells due to relief of AR-mediated feedback repression of GR expressi

20 Relief of AS by transcatheter aortic valve implantation

21 Relief of auto-inhibition to an active, open state, due

22 ion of the auto-inhibitory segment, and thus relief of auto-inhibition, requires the recruitment of C

23 adigm for WASP regulation invokes allosteric relief of autoinhibition by diverse upstream activators.

24 was reported that Hsl1p activation involved relief of autoinhibition in response to septin interacti

25 iation, our data show that force-independent relief of autoinhibition is sufficient to mediate their

26 a more accessible ABL catalytic site through relief of autoinhibition.

27 his construction enables efficient, stepwise relief of autoinhibition: initial phosphorylation events

28 Relief of aversive states, including pain, is rewarding.

29 smolarity, and this reduction was due to the relief of betaine-mediated suppression of compatible sol

30 group than in the placebo group had adequate relief of bloating (39.5% vs. 28.7%, P=0.005, in TARGET

31 also use a poultice of these leaves for the relief of body pains.

32 with room air delivered by nasal cannula for relief of breathlessness in this population of patients.

33 I-V curve, consistent with a K(+) -dependent relief of Ca(2+) inactivation of G(K(LV)) .

34 ay result largely from a potassium-sensitive relief of Ca(2+) inactivation of the channel pore select

35 f opioid analgesics, which is crucial to the relief of cancer pain, there is a lack of evidence to su

36 sma0113 in-frame deletion mutants show a relief of catabolite repression compared to the wild typ

37 uture studies should focus on prevention and relief of chemotherapy-induced neuropathy.

38 ate analgesic drugs such as morphine for the relief of chronic pain may result in the development of

39 tin, and that cannabinoids provide long-term relief of chronic pain states.

40 ssurance for women with hysterectomy seeking relief of climacteric symptoms in terms of the effects o

41 ive hospice care, including the presence and relief of common symptoms (ie, pain, dyspnea), concordan

42 The relief of "compressional" strain serves to explain the d

43 to millisecond duration) as a mechanism for relief of compressive forces in the tested dsDNAs.

44 s) and infants (31 days to 1 year) underwent relief of congenital aortic stenosis.

45 theter aortic valvuloplasty is effective for relief of congenital AS, there are steady long-term haza

46 h fewer signs of organ damage and more rapid relief of congestion during the first days after admissi

47 ms in patients with acute heart failure, and relief of congestion is a critical goal of therapy.

48 Severity of constipation, adequate relief of constipation, global relief of constipation, t

49 ion, adequate relief of constipation, global relief of constipation, treatment satisfaction, quality

50 For relief of coronary obstruction, percutaneous coronary in

51 The findings indicate that smoking-induced relief of craving and withdrawal reflects primarily non-

52 rm facilitation (S pathway), consistent with relief of cross-talk inhibition.

53 has the potential to be useful for prolonged relief of cutaneous pain and might have a use as a resea

54 been associated with antitumour activity and relief of debilitating symptoms in patients with advance

55 e desensitizing dentifrices to provide rapid relief of dentin hypersensitivity (DH).

56 neuropsychological mechanisms to bring about relief of depressed mood.

57 prefrontal cortex activity correlate with a relief of depression symptoms.

58 trial pressure; r=0.67; P=0.003), suggesting relief of diastolic ventricular interaction as a contrib

59 duction of p53 activity and partially due to relief of direct repression by BCL6 of p53 target genes.

60 During relief of dormancy, H3K27me3 repressive marks slowly acc

61 Relief of ductal obstruction in BDL rats reduced Hh path

62 All patients had relief of dysphagia [dysphagia score </= 1 ("rare")].

63 in patients with RBES may lead to long-term relief of dysphagia in 30 and 40% of patients, respectiv

64 e is approved in the United States for early relief of dyspnea in patients with acute heart failure.

65 sure, relaxin was associated with favourable relief of dyspnoea and other clinical outcomes, with acc

66 entionally believed to be due principally to relief of dyssynchrony, although we recently showed that

67 the glioblastoma vascular microenvironment, relief of edema, and depletion of regulatory T and endot

68 gulation of EphB receptor expression through relief of endocytosis and degradation.

69 down expression of mutant MYOC, resulting in relief of ER stress.

70 ibit RAF monomers and ERK signaling, causing relief of ERK-dependent feedback, reactivation of ligand

71 r effect is caused, at least in part, by the relief of ERK-mediated RAF inhibition.

72 is restored after TAVI, suggesting an acute relief of excess compression in systole that likely bene

73 tive, inhibiting SOM neurons, which leads to relief of excitatory neurons from suppression.

74 ronic situation, which is facilitated by the relief of excited state antiaromaticity of the benzene r

75 Herein, we clarify to what extent relief of excited-state antiaromaticity (ESAA) triggers

76 ssynchrony, although we recently showed that relief of external constraint to left ventricular fillin

77 related to both contractile improvement and relief of external constraint.

78 The primary end point was adequate relief of FD symptoms for >/=5 weeks of the last 10 week

79 e proposed that this increase was due to the relief of feedback inhibition of translation as a conseq

80 However, this relief of flap-inhibition does not simply originate from

81 19%]), fenestration creation (15 [48%]), and relief of Fontan obstruction (7 [23%]).

82 om SERCA by high calcium during systole, and relief of functional inhibition does not require dissoci

83 or cardiac function does not translate into relief of functional intolerance in patients with COPD o

84 Facilitation caused by frequency-dependent relief of GABABR-mediated inhibition was observed when t

85 Based on this, we propose that ERK-dependent relief of gene repression by Cic is a two-step process,

86 ective way, and ultimately contribute to the relief of global energy and climate issues.Energy wasted

87 group than in the placebo group had adequate relief of global IBS symptoms during the first 4 weeks a

88 the proportion of patients who had adequate relief of global IBS symptoms, and the key secondary end

89 This indicates that the relief of glucose repression is already operable at much

90 lectively attenuates beta 2AR signaling, yet relief of GRK2/3-dependent beta 2AR desensitization does

91 on of ihtA with the cognate hctA resulted in relief of growth repression.

92 to warm to analyze the role of T6P/SnRK1 in relief of growth restriction.

93 downregulation of miR-1 is necessary for the relief of growth-related target genes from its repressiv

94 her proportion of patients reported adequate relief of gut symptoms following the low FODMAP diet (14

95 Our results indicate that relief of H-NS repression and recruitment of RNA polymer

96 expression: activation of transcription and relief of H-NS-mediated repression.

97 behavior-may offer a viable intervention for relief of HF.

98 unrelieved dyspnea and oxygen for short-term relief of hypoxemia.

99 Here, we report that relief of hypoxia in the developing cerebral cortex by i

100 The primary efficacy end point, relief of IBS pain and discomfort, improved significantl

101 The co-primary endpoint was overall relief of IBS symptoms, as defined by the European Medic

102 h rifaximin for 2 weeks provided significant relief of IBS symptoms, bloating, abdominal pain, and lo

103 The primary outcome was adequate relief of IBS symptoms, with responders defined as patie

104 the proportion of patients who had adequate relief of IBS-related bloating, were assessed weekly.

105 The TR binding to this site triggers the relief of Ig20 and protein kinase A (PKA)-mediated phosp

106 nd complement-dependent cytotoxicity through relief of immunosuppression.

107 steroidal anti-inflammatory drug (NSAID) for relief of inflammatory pain.

108 after SVP by using a strategy consisting of relief of inflow and outflow tract obstructions, resecti

109 Id3 was required for relief of inhibition by the transcription factor GATA-3

110 teine cross-linking approach, we showed that relief of inhibition following cleavage requires dissoci

111 te (T state) of the protein (PLN), while the relief of inhibition involves promotion of PLN to excite

112 We propose that relief of inhibition may be mediated by the activity of

113 so inhibited BK, although acidosis-dependent relief of inhibition varied.

114 that increases in these enzymes were due to relief of inhibitory glucocorticoid signaling.

115 e pointing to nucleoid-wide accumulation and relief of internal stress.

116 Relief of intra-abdominal hypertension may be instrument

117 ed tethers, implying cyclic accumulation and relief of intranucleoid mechanical stress.

118 Relief of intratumor immunosuppression may increase cons

119 Relief of iron (Fe) limitation in the Southern Ocean dur

120 tion of PI3K thus requires both PKA-mediated relief of IRS1 inhibition and IGF-1R-dependent tyrosine

121 ypochlorous acid (HOCl) formulations lead to relief of itch in human patients with atopic dermatitis;

122 ticosteroids with respect to practicability, relief of itch, and improvement in quality of life.

123 nal changes of Sso2 that are crucial for the relief of its auto-inhibition.

124 MCA), causing the release of this domain and relief of its autoinhibitory function.

125 myopathy patients undergoing surgery for the relief of left ventricular outflow tract obstruction hav

126 uary 1997 and December 2007 for the surgical relief of left ventricular outflow tract obstruction.

127 cardiomyopathy patients undergoing surgical relief of left ventricular outflow tract obstruction.

128 ticosteroid injections offer only short-term relief of leg pain and disability for patients with scia

129 ction that enables growth recovery following relief of limitations such as low temperature.

130 and after vulval induction, suggesting that relief of LIN-1-mediated repression in P6.p is likely du

131 Duloxetine exerts only modest relief of male stress urinary incontinence, but may be r

132 herapy is commonly prescribed for palliative relief of malignant dysphagia in patients with incurable

133 valid approach in the treatment, or at least relief, of many acute and chronic pathologies, such as i

134 phocytes (CTL) in the TME, consistent with a relief of MDSC-mediated immunosuppression.

135 se, and the twisting was associated with the relief of mechanical shear stress in assembled ribbons c

136 e natural menopause and were treated for the relief of menopausal symptoms.

137 sed steady-state translation, in part due to relief of microRNA-mediated silencing, this work demonst

138 therapeutic strategies only give symptomatic relief of motor impairment and do not address the underl

139 Device implantation was successful with relief of MR in all 9 patients.

140 Post-conditioning, or relief of myocardial ischemia in a stuttered manner, has

141 to excessive alcohol ingestion motivated by relief of negative emotionality.

142 ll patients had dysphagia relief, 83% having relief of noncardiac chest pain.

143 Overall, 138 (46%) patients had surgical relief of obstruction (91% myectomy) and 6 (2%) alcohol

144 tal myectomy is highly effective with a >90% relief of obstruction and improvement in symptoms.

145 hy, who do not uniformly experience complete relief of obstruction and symptoms.

146 he importance of patient selection, adequate relief of obstruction, and measures to prevent and manag

147 ive for migraine headache selectively elicit relief of ongoing cephalic, but not postsurgical, noncep

148 ids and laxatives for 3 or more days without relief of opioid-induced constipation were randomly assi

149 alternatively, alcohol septal ablation) for relief of outflow obstruction and symptoms of heart fail

150 luated by using subjective criteria, from no relief of pain (= 1) to complete relief of pain (= 4).

151 ia, from no relief of pain (= 1) to complete relief of pain (= 4).

152 Relief of pain activates the dopaminergic reward pathway

153 Aspirin is widely used for relief of pain and for cardioprotective effects.

154 f arterial occlusion is too severe to permit relief of pain and healing of ischemic ulcers.

155 ACC opioid neurotransmission is required for relief of pain and subsequent downstream activation of N

156 ears to be both necessary and sufficient for relief of pain aversiveness.

157 c ablation, and excision are associated with relief of pain due to endometriosis.

158 n in vivo film implantation showed effective relief of pain for more than 4 days post-implantation an

159 Relief of pain from organ directed treatment of chronic

160 Because relief of pain is rewarding, analgesic agents that are n

161 Relief of pain is rewarding.

162 ools in neurological disorder as well as for relief of pain or in comorbidity of anxiety states and d

163 e that patients are forced to choose between relief of pain or itch.

164 he data directly support the hypothesis that relief of pain produces negative reinforcement through a

165 siveness of pain, as well as the reward from relief of pain, is encoded by brain reward/motivational

166 other opioids offer dramatic and impressive relief of pain, their impact is truncated by loss of eff

167 ed with depression of behavior and mood, and relief of pain-related depression is a common goal of tr

168 st "on" treatment value) in daily "on" time (relief of parkinsonian motor features) without troubleso

169 ons was neither necessary nor sufficient for relief of parkinsonian symptoms.

170 These advances have led to relief of patients' symptoms and improved quality of lif

171 y significant proven benefit for symptomatic relief of pelvic organ prolapse and improvement of quali

172 stroke volume or a (desirable) compensatory relief of peripheral vasoconstriction.

173 sis would pay a lifetime cost of $11,498 for relief of physical symptoms and emotional health; howeve

174 Here, we demonstrate that relief of PKC-mediated desensitization of endogenous Cys

175 Relief of PLN inhibition is length-dependent, allowing S

176 MPAR pore size, suggesting that TARP-induced relief of polyamine block does not reflect altered pore

177 Relief of polyamine block in GluK2/GluK5 heteromers resu

178 dditive effect to heteromerization, and thus relief of polyamine block is due to a different mechanis

179 MA401 (100 mg twice daily) provides superior relief of postherpetic neuralgia compared with placebo a

180 We conclude that relief of PraR-mediated repression determines a lifestyl

181 d directly by mTOR, thus contributing to the relief of PRAS40-mediated substrate competition.

182 Lon-mediated relief of proteotoxic stress and protein aggregation in

183 gly suggest that ESIs can provide short-term relief of radicular symptoms but are less convincing for

184 ovides no additional symptomatic benefit for relief of refractory dyspnoea in patients with life-limi

185 ative to long-term changes in subsidence and relief of regional lithology must be considered for expl

186 The relief of repression allows expression of HXT transporte

187 Hence, we conclude that both relief of repression and adoption of an activating form

188 These findings support the model of relief of repression as the mechanism of restoration of

189 anslocase subunit further indicate that this relief of repression is achieved through expending energ

190 Similar relief of repression is also observed upon overexpressio

191 Relief of repression is associated with defective affini

192 e show that this induction involves both the relief of repression mediated by the enhancer-blocking p

193 Relief of repression of lag-2 in P6.p offers a plausible

194 antagonizes bowl to promote Dl expression by relief-of-repression.

195 BST-2 from the cell surface and the optimal relief of restricted virion release.

196 ination of BST-2 and that this underlies the relief of restriction.

197 EV1 is modified by SUMO2/3, resulting in the relief of REV1's inhibition of p53 and enhancing p53's e

198 atients underwent 11 reoperations, including relief of right ventricular outflow tract obstruction (n

199 ne ring to the palladium(0) catalyst and the relief of ring strain as a driving force for product for

200 odel in which fluorogenicity arises from the relief of ring strain.

201 ted repression of the RUNX1 promoter and the relief of RUNX1-directed growth repression.

202 ine, promoting methyltransferase activity by relief of SAH inhibition.

203 ion of phospholamban by protein kinase A and relief of sarco/endoplasmic reticulum Ca(2+)-ATPase inhi

204 guided popliteal sciatic nerve block for the relief of severe rest pain during endovascular treatment

205 Relief of SMURF2 autoinhibition is induced by TGFbeta an

206 analysis of mutants that bypass the need for relief of SpoIVFB inhibition.

207 determined using von Frey filaments, and the relief of spontaneous pain was determined by using place

208 By multivariate analysis, having the relief of stenosis by balloon valvuloplasty and undergoi

209 ation by the mutant does not result from the relief of steric incompatibility in the fiber state.

210 hich the cleavage is accompanied by either a relief of strain energy or the formation of an aromatic

211 a cyclic carbenium ion intermediate, (2) the relief of strain in the methylenecyclopropane moiety pro

212 Relief of strain, avoidance of antiaromaticity, and incr

213 Upon relief of stress, HBO1 reassociates with replication ori

214 to the activation of the enhancer following relief of Su(H)-mediated default repression by the Notch

215 Loss of HPr resulted in partial relief of succinate-mediated catabolite repression, extr

216 in the presence of PI4P and demonstrate that relief of such auto-inhibition remains compatible with s

217 Palliative care is focused on the relief of suffering, in all of its dimensions, throughou

218 action between the interventions in adequate relief of symptoms (P = .52) or Bifidobacterium species

219 The relief of symptoms after conservative therapy predicts b

220 (PEH) has been shown to result in excellent relief of symptoms and improved quality of life (QOL) de

221 that treatment with serelaxin may result in relief of symptoms and in better outcomes in patients wi

222 Steroid treatment provided good relief of symptoms and patients were advised to avoid po

223 The co-primary endpoints were adequate relief of symptoms and stool Bifidobacterium species abu

224 pe natriuretic peptide (NT-proBNP) level-and relief of symptoms as defined by the dyspnea visual anal

225 Surgical treatment resulted in a better relief of symptoms compare to conservative therapy.

226 Adequate relief was defined as self-reported relief of symptoms for at least 2 of the first 4 weeks a

227 Long-term relief of symptoms has the potential to improve overall

228 ssociated with modest benefit for short-term relief of symptoms in adults with severe symptoms of acu

229 is feasible and acceptably safe and provides relief of symptoms in most patients (90%); however, abou

230 All patients reported relief of symptoms on postprocedure day 1.

231 Therapy-associated relief of symptoms was paralleled by substantial gains i

232 hs) follow-up was available, 12 had complete relief of symptoms with no need for medications and full

233 use of short-acting beta2-agonists for rapid relief of symptoms, and daily use of inhaled corticoster

234 morbidity and mortality, prompt and durable relief of symptoms, and maintenance of liver function.

235 edications are often used for a period, with relief of symptoms, and then discontinued, after which r

236 ect was observed on time to the beginning of relief of symptoms, on time to resolution of symptoms, a

237 ajority of patients experience a significant relief of symptoms, there is a substantial risk of reinn

238 (100 mug per actuation) by MDI as needed for relief of symptoms.

239 engthy medication trials before experiencing relief of symptoms.

240 issue regeneration and yield only short-term relief of symptoms.

241 nide and formoterol for both maintenance and relief of symptoms.

242 olization led to improved albumin levels and relief of symptoms.

243 ns unclear which treatment provides the best relief of symptoms.

244 MDI), with one extra actuation as needed for relief of symptoms; treatment in the standard group cons

245 In cells with elevated betaCaMKII, relief of synaptic-activity blockade uncovered an increa

246 aromatization processes likely are driven by relief of the considerable ring strain of the silaazirid

247 of the DNA strand with the quencher and thus relief of the contact quenching, resulting in a change o

248 all cases, in addition to the generation or relief of the curvature stress, the buds recruit specifi

249 t contribute to the preservation rather than relief of the effects of frustration.

250 Relief of the elongation block is associated with recrui

251 cial erosion explains the high elevation and relief of the Gamburtsevs.

252 This pH change may provide relief of the H+ block of NMDA receptors (NMDARs) and th

253 ption of halted transcripts was resumed upon relief of the heat shock.

254 of TAG synthesis 2-fold, leading to complete relief of the low-oil phenotype.

255 Use of oral drugs to provide symptomatic relief of the movement disorders is limited by adverse e

256 teral nutrition until weight gain results in relief of the obstruction.

257 roblasts were completely depleted 4 wk after relief of the obstruction.

258 treatment brought only partial and temporary relief of the pain and symptoms.

259 y aortic constriction and improved following relief of the pressure gradient.

260 bstruction and PR, but it is unknown whether relief of the right ventricular volume and/or pressure o

261 tent with a typical lifespan when mechanical relief of the stenosis is provided in a timely fashion.

262 Following relief of the stress, the growth arrest and DNA damage-i

263 Relief of the underlying SVC obstruction is the cornerst

264 in temporizing active variceal bleeding, but relief of the underlying SVC obstruction is the cornerst

265 The sharpness and relief of the worn cusp apices of teeth (mesowear) are a

266 ion procedures excluded 288 patients: 42 had relief of their heartburn during the 2-week omeprazole t

267 after interventional catheterization and the relief of their stenosis lasts longer.

268 regulated by negative feedback circuits and relief of these circuits represents a common mechanism o

269 itial photoexcitation, and by the subsequent relief of this antiaromaticity as the reaction progresse

270 stage due to cell cycle quiescence, and that relief of this block during the third larval stage relie

271 Relief of this feedback limits the sustained inhibition

272 Upon relief of this inhibition, SnRK2 kinases can autoactivat

273 Relief of this steric clash ensures the subsequent 6pi r

274 cteriophage lambda PR-PRE system show strong relief of TI and a lack of dislodgement and roadblocking

275 In vivo measurements of relief of TI by CI or Cro repressors in the bacteriophag

276 moters, stochastic simulations indicate that relief of TI can be inhibited if the repressor at the in

277 R Cas9 protein gave either compromised or no relief of TI depending on the orientation at which it bi

278 evolutionarily tuned to set the magnitude of relief of TI.

279 ected by alpha-B crystallin probably through relief of titin aggregation.

280 y to unlock growth-defense tradeoffs through relief of transcription repression provides an approach

281 iption arises from antitoxin degradation and relief of transcriptional autoregulation.

282 plained by increased P2 transcription due to relief of transcriptional interference, by a 3-fold more

283 histone ubiquitination may link DNA repair, relief of transcriptional repression, and activation of

284 ure of systems in which ERK induces genes by relief of transcriptional repression.

285 We show that the advantage arises from relief of translational competition between GAL1 transcr

286 Upon relief of tumor hypoxia, PMNs were recruited less intens

287 on of IBTKalpha mRNA involves stress-induced relief of two inhibitory upstream open reading frames in

288 Resurgent currents arise after relief of ultra-fast open-channel block mediated by an e

289 Even after relief of valve obstruction in patients with aortic sten

290 lycine and glutamate in combination with the relief of voltage-dependent magnesium block to open an i

291 An emphasis on early relief of volume and pressure overload culminating in th

292 e ondansetron, have demonstrated efficacy in relief of vomiting, decreased need for intravenous fluid

293 nking inductive and lateral signaling is the relief of VPC-wide lag-2 repression in P6.p.

294 s, such as lower abuse liability and induced relief of withdrawal symptoms and drug cravings, despite

295 anticipation of pleasure from cigarettes and relief of withdrawal symptoms.

296 By contrast, relief of withdrawal-related attentional deficits and ci

297 ed ubiquitin variants is largely mediated by relief of WW domain linker autoinhibition.

298 ation of YAP in lysosomes and, consequently, relief of YAP-mediated inhibition of the cellular antivi

299 The relief of Zn(2+) inhibition by plasmin occurs in PAR1(-/

300 or removal of the amino-terminal domain and relief of Zn(2+) inhibition.