1 se and its consequences in the US population
remain.
2 position, we believe that achievement of the
remaining ~
0.5% in anode reversibility will require fres
3 This
remained 100-fold lower than baseline during the 3 year-
4 erefore excluded from efficacy analyses; the
remaining 151 patients were included in the per-protocol
5 Our meta-analysis focused on the
remaining 29 human studies, including twelve human datas
6 n, 41 (4.4%) had HUS at presentation; of the
remaining 886, 126 (14.2%) developed HUS.
7 ive nontyphoidal Salmonellosis in particular
remain a major health and economic burden worldwide.
8 with a few molecules in artificial cells has
remained a challenge.
9 xchange on chip for large numbers of embryos
remains a bottleneck.
10 , processing the resulting radiomic datasets
remains a challenge due to the lack of specific tools fo
11 the effects of m(6)A on viral and host RNAs
remains a challenge for the field.
12 Achieving long-range uniformity
remains a challenge, but this process could provide a ro
13 trait changes through particular communities
remains a challenge.
14 r risk stratification to guide interventions
remains a challenge.
15 Drug delivery to the brain always
remains a challenging issue for scientists due to the co
16 stoscopy improves diagnostic sensitivity, it
remains a costly and invasive approach.
17 ions in COVID-19, lung transplantation (LTx)
remains a critical life-saving operation.
18 upports (N-doped carbon, metal oxides, etc.)
remains a formidable challenge, especially under high-te
19 ing genomic variation to phenotypical traits
remains a major challenge in evolutionary genetics.
20 gens, acquired resistance to hormone therapy
remains a major challenge in treating advanced prostate
21 While postoperative myocardial injury
remains a major driver of morbidity and mortality, the a
22 This
remains a particularly acute problem for triploids, whic
23 proved vaccines that elicit broader immunity
remains a public health priority.
24 Spinal cord injury
remains a scientific and therapeutic challenge with grea
25 Actuation
remains a significant challenge in soft robotics.
26 ti-redox reaction on metal-oxide photoanodes
remains a significant experimental and theoretical chall
27 order and cation-oxygen-vacancy coordination
remains a subject of active debate.
28 nd that splitter neurons were more likely to
remain active and retained more consistent spatial infor
29 icated that the sensitivity of the electrode
remains active for several runs of the analysis.
30 ts were deceased, 28 were discharged, and 26
remained admitted.
31 Strong significant inter-hospital variation
remained after adjustment for the major clinical conditi
32 No significant (P < .01) covariates
remained after backward elimination and no effect of asp
33 These groupings
remained after sex adjustment.
34 ate-to-high doses of opioids and expected to
remain alive and ventilated for an additional 48 hours a
35 orter dysfunction to disease pathophysiology
remain ambiguous as the fundamental relationship between
36 Sepsis
remains among the most common complications from infecti
37 However, matter-wave interferometry has
remained an outstanding challenge for natural polypeptid
38 tection of low-abundance proteins from blood
remains an unsolved challenge due to the extraordinary d
39 de of antimicrobial MR1-dependent activation
remained as potent and polyfunctional as with younger ad
40 d HbA1c > 5.7% (aOR 5.82, 95% CI 1.50-22.54)
remained associated with presence of cysts and solid les
41 More than half the patients
remained asymptomatic during the stress test.
42 d high-risk, age-matched HTLV-1 carriers who
remained ATL-free after a median of 10 years of follow-u
43 and produces two-fragment holoreceptors that
remain bound at the cell surface.
44 resented HRCT features of active PTB and the
remaining cases were negative but had presented a few fe
45 ellular populations without side effects has
remained challenging.
46 ters for gastrointestinal (GI) tract imaging
remains challenging due to fluorescence quenching in the
47 l role in development and evolution, the LPM
remains challenging to study and to delineate, owing to
48 d shapes and sizes in the range of 10-100 nm
remains challenging.
49 saving the species from extinction, condors
remain compromised by lead poisoning and limited genetic
50 rse-grained level, but atomistic simulations
remain computationally challenging.
51 lucose utilization should not be expected to
remain constant.
52 was associated with a lower hazard when PAEE
remained constant (for example, 30% (8-47%) lower hazard
53 SERCA function
remains constant in CH but decreases (tau for SERCA-medi
54 the complexities of DENV immunopathogenesis
remain controversial.
55 promoted regenerative proliferation, but YAP
remained cytoplasmic and little proliferation occurred i
56 s and the paradigms through which they arise
remain debated.
57 ly light carbon, although the carbon sources
remain debated.
58 ases signal diversity during clade radiation
remains debated.
59 in our understanding of Alzheimer's disease
remain despite intense research efforts.
60 s to help address the most common cases that
remain difficult for text-mining tools.
61 s and within dynamic molecular regimes often
remain difficult to ascertain.
62 However, tumors less than 1 cm in size still
remain difficult to localize by conventional means becau
63 s of interest prior to analysis; however, it
remains difficult to isolate and then single-cell sequen
64 tood as potential underlying pathomechanisms
remain elusive, and no relationship to the administered
65 ular events underlying HIV neuropathogenesis
remain elusive, mainly due to lack of brain-representati
66 However, their charge transport properties
remain elusive, plagued by the issues of excessive conta
67 of STEAP1 and its role in cancer progression
remain elusive.
68 glA, but the underlying molecular mechanisms
remain elusive.
69 ound organelles such as the Golgi apparatus,
remain elusive.
70 ecular mechanisms underlying photoactivation
remain elusive.
71 als supervising these phenotypic transitions
remain elusive.
72 its (e.g., mild, moderate or severe drought)
remain elusive.
73 the molecular nature of this requirement has
remained elusive despite intensive study.
74 , the causes of evolutionary constraint have
remained elusive due to a poor mechanistic understanding
75 e role of PKI proteins in these pathways has
remained elusive.
76 se, its implications on global-scale climate
remains elusive in current ESMs.
77 t least 200 years, yet the trigger mechanism
remains elusive(1).
78 LMP2A signaling contributes to tumorigenesis
remains elusive.
79 he performance of contact-assisted threading
remains elusive.
80 ation dynamics during inflammatory responses
remain enigmatic.
81 ported, but many of these noncanonical roles
remain enigmatic.
82 ation, and filament growth in cable bacteria
remains enigmatic.
83 complex area in which many further questions
remain,
especially regarding the well-conducted studies
84 We found at least 28% of the global total
remaining extent of LPE was affected in Florida alone.
85 linical effectiveness of beta-lactams, which
remain first-line antibiotics for many infections, is an
86 The precise roles of the five
remaining genes (Flcn, Map1lc3b, Me2, Prkd2, and Scarb2)
87 deleted in gut using Villin-Cre, female mice
remain healthy despite significant X-autosome dosage imb
88 At birth, infants who
remained healthy had significantly higher RSV-A and RSV-
89 ular structures in complex tissues that have
remained hidden until now.
90 However, restenosis rates
remain high.
91 M-MDSCs
remained high for 1 y posttransplantation.
92 Mortality
remains high, but the majority of patients were discharg
93 ing the development of the visual cortex and
remains high.
94 discharged alive, 178 (29%) died and 55 (9%)
remained hospitalized at censoring.
95 dence and outcome in critically ill patients
remain,
however, largely unknown.
96 matchmaking RNA chaperone, significant gaps
remain in our understanding of the molecular mechanisms
97 g layer of focal adhesions, whereas vinculin
remained in its normal position within the force transdu
98 sorder (OUD) treatment during therapy, and 9
remained in OUD treatment after completion of DAA treatm
99 Significant carriage of these serotypes
remains in all age groups.
100 Even so, today, most of Antarctica
remains in the grip of continental ice sheets, with only
101 cell (dSPB) during anaphase and the SPB that
remains in the mother cell.
102 al solutions show that such scale separation
remains in the strongly nonlinear turbulent regime, prov
103 ase mutations lead to the migraine phenotype
remain incompletely understood.
104 cruitment to inflammatory micro-environments
remain incompletely understood.
105 e mechanisms responsible for these phenomena
remain incompletely understood.
106 leoids are formed and regulated within cells
remains incompletely resolved.
107 regulates adipocyte development and function
remains incompletely understood.
108 ying mechanism of BAX and BAK pore formation
remains incompletely understood.
109 lignant transformation at the junction areas
remain insufficiently elucidated.
110 echanisms underlying specific dream contents
remain largely elusive.
111 ci selected for improving grain productivity
remain largely unclear.
112 e and physical properties of these materials
remain largely unknown.
113 nation from the primary site to the skeleton
remain largely unknown.
114 ing enzymatic activities, the rates of which
remain largely unknown.
115 onment (TME) and its molecular underpinnings
remain largely unstudied.
116 rust, lower crust gabbros in particular, has
remained largely unexplored by microbiologists.
117 in rTg4510 mice, while head-direction tuning
remains largely intact.
118 e central role of alpha-klotho in metabolism
remains largely unexplored.
119 seasonal dynamics of ecosystem productivity
remains largely unknown.
120 or rise to detectable frequencies by chance
remains largely unknown.
121 ities modulates plant species' distributions
remains largely untested.
122 However, patient access
remains limited because of restricted insurance coverage
123 lity to accurately identify patients at risk
remains limited despite decades of clinical research.
124 itive cysteines in the human immune proteome
remains limited.
125 ty to tailor their structures and properties
remains limited.
126 roparticles self-aggregate into a depot that
remains localized and maintains therapeutic levels of su
127 al failure and immunological graft rejection
remain long-term complications leading to late graft fai
128 l agent, SARS-CoV-2, in the human population
remains mysterious, although bat and pangolin were propo
129 ad 3-times higher risk compared to those who
remained negative (21.8% vs 8.5%, p=0.01; OR 3.0, 95%CI
130 d resistance to enzymatic degradation, while
remaining nontoxic.
131 nes in preventing infectious diseases, there
remain numerous globally devastating diseases without fu
132 The true ecological function of most SMs
remains obscure, but understanding of both the activatio
133 Calculus
remained on the roots surfaces after they were judged to
134 ollow-up period during which CsA CE patients
remained on their original regimen (CsA CE 4 times daily
135 ney transplantation (KT) compared with those
remaining on dialysis.
136 Stroke
remains one of the leading causes of permanent disabilit
137 Cigarette smoking
remains one of the leading public health threats worldwi
138 risk factors, with a significant association
remaining only for ACR (>=103 compared with 5 mg/g) and
139 is more responsible for phenotypic variation
remains opaque.
140 maS or ADP, whereas the apo MCM2-5 interface
remains open.
141 Despite medical advancements, it's prognosis
remains poor as many patients with heart failure experie
142 l survival in patients with relapsed disease
remains poor, and thus novel therapeutic approaches are
143 e fundamental aspects of protein-DNA binding
remain poorly understood(1,2).
144 and temperature signaling pathways in plants
remain poorly understood.
145 s droughts, are overlooked and their impacts
remain poorly understood.
146 ixing on the membrane biophysical properties
remain poorly understood.
147 the mechanisms linking these two phenomena,
remain poorly understood.
148 erpin mutational selection in normal tissues
remain poorly understood.
149 re is intrinsically disordered and therefore
remains poorly characterized.
150 type, the associated capsular polysaccharide
remains poorly characterized.
151 r, basic understanding of dog sleep patterns
remains poorly characterized.
152 e contribution of ZO-1 to cardiac physiology
remains poorly defined.
153 Yet, this specific subset of patients
remains poorly described.
154 thic pain disorders, is highly prevalent but
remains poorly treated.
155 y investigated, the genetic etiology of NTDs
remains poorly understood.
156 ied, precisely how gamma-TuRC nucleates a MT
remains poorly understood.
157 but how they affect substrate conformations
remains poorly understood.
158 egulatory elements, yet how this is achieved
remains poorly understood.
159 nity against hemibiotrophic fungal infection
remains poorly understood.
160 over to large-scale hydroclimate variability
remains poorly understood.
161 ocessing higher up in the cortical hierarchy
remains poorly understood.
162 The cost associated with a hybrid suite
remains prohibitive for many centers.
163 The Expert Panel continues to endorse the
remaining recommendations for second-line chemotherapy,
164 the stability of intron-retained transcripts
remained relatively constant.
165 iviral detection mechanisms in the cytoplasm
remains relatively uncharacterized.
166 tro, but its cardiovascular function in vivo
remains relatively unexplored.
167 demic's overall effect on the RRT population
remained remarkably limited in Flanders.
168 release at the fewer, but larger, individual
remaining ribbon synapses colocalized with the post-syna
169 fibrillator (ICD) in this patient population
remain scarce.
170 in other physiological processes and species
remains scarce.
171 iatric disorders; its pharmacology, however,
remains scarcely understood.
172 The resulting burns
remain sensitive to touch for weeks, but it is unknown w
173 There
remain significant regional disparities in the managemen
174 rse ratio on day 1 and in-hospital mortality
remained significant (odds ratios, 1.29 and 1.26, respec
175 These effects
remained significant after excluding nonrandomized trial
176 abase lock, median progression-free survival
remained significantly improved with ramucirumab compare
177 me-of-interest quantitation showed that SUVs
remain stable down to 1/3 dose (1.2 MBq/kg).
178 -cadherin-mediated cell adhesion, LC numbers
remained stable and similar as in control mice, even in
179 rated in presence of oxygen (100 kPa), which
remained stable up to 22 h.
180 used to the last 10 amino acids of SpxA2 but
remained stable when fused to the C-terminal acidic tail
181 the pandemic, discard rates across organ has
remained stable.
182 itations caused by physical health problems)
remained statistically significant (P < 0.01).
183 l attainment attenuated after adjustment but
remained strong; for example, the OR after adjustment fo
184 om clinical trials of various AKT inhibitors
remain suboptimal, suggesting that AKT-driven tumor meta
185 ion dose with concurrent chemotherapy should
remain the standard of care, with the OS rate being amon
186 nthesis products from single microbial cells
remains the bottleneck for determining the specific turn
187 Endometrial cancer
remains the most common gynecological malignancy in the
188 /moderate glaucoma, whereas cpRNFL thickness
remains the most efficient for advanced glaucoma.
189 The NIH
remains the primary public funding source for surgical r
190 However, stroke
remains the second leading cause of death worldwide and
191 have received scant scrutiny and, crucially,
remain to be addressed.
192 rse set of other putative defense genes that
remain to be characterized.
193 nes (Flcn, Map1lc3b, Me2, Prkd2, and Scarb2)
remain to be determined.
194 ys a role in maintenance of genome stability
remain to be determined.
195 l survival and apoptosis signaling in cancer
remain to be elucidated.
196 late to the cognitive and affective deficits
remains to be determined with a large cohort of particip
197 isoforms whose biological relevance largely
remains to be determined.
198 , such as protein-protein interaction (PPI),
remains to be elucidated.
199 metabolism to support the dynamic phenotype
remains to be established.
200 ether this link has any causal aspects to it
remains to be explored.
201 gress in protein structure prediction, a lot
remains to be studied at this merging superhighway of de
202 ocesses in vivo and development in metazoans
remains to be understood.
203 All
remaining topics reviewed were addressed with evidence u
204 mor margins and adjuvant therapies to ablate
remaining tumor tissues are needed during surgical resec
205 AnxA8 gene expression, on the other hand,
remained unaltered upon manipulating Wnt signalling, sug
206 s are confounding materials whose properties
remain uncertain, even after years of study.
207 echanisms behind this directed movement have
remained uncertain.
208 sion, yet the underlying molecular mechanism
remains uncertain.
209 long-term continued survival of right whales
remains uncertain.
210 oligonucleotides the number of binding sites
remained unchanged with pressure rise while an increase
211 Although the canonical pathway
remained unchanged, autocrine SHH interference in colon,
212 and control conditions, while motor strength
remained unchanged.
213 ile the proportion in non-intervention sites
remained unchanged.
214 reg-specific demethylated region (TSDR) have
remained unchanged.
215 interactions between antibiotics and phages
remain unclear, in particular, whether and when phages c
216 Though its therapeutic mechanisms
remain unclear, it has been suggested that antidromic ac
217 However, its effects on OPOA
remain unclear.
218 c determinants of CHK1 inhibitor sensitivity
remain unclear.
219 rocesses that govern cocaine potency in vivo
remain unclear.
220 -sensing mechanisms and disease consequences
remain unclear.
221 riable severity of peanut-allergic reactions
remain unclear.
222 mmunity, the pathways driving this phenotype
remain unclear.
223 e mechanisms of AXL overexpression in cancer
remain unclear.
224 AD), but several aspects of this association
remain unclear.
225 gands in such intriguing additional capacity
remain unclear.
226 the background interacts with Mendelian loci
remain unclear.
227 ommon and optimal immunosuppressive regimens
remain unclear.
228 ll development, but the underlying mechanism
remained unclear.
229 However, it
remains unclear how neocortex maintains this asynchronou
230 It
remains unclear how these pathways interact to contribut
231 intensively studied in colorectal cancer, it
remains unclear whether activity in the tumor-associated
232 However, it
remains unclear whether this trend will continue, preven
233 atory syndrome coronavirus 2 illness, but it
remains unclear whether underlying asthma is associated
234 roteins localize to the nucleus; however, it
remains unclear which contain transcriptional effectors.
235 Contemporary incidence
remains unclear with few recent nationwide studies and l
236 ysiological relevance of this cleavage event
remains unclear, although it is thought to inhibit activ
237 suppression of predicted sensory information
remains unclear, and studies thus far have revealed a mi
238 the fundamental predictability of structures
remains unclear, as networks' complex underlying formati
239 e regulation of general cellular homeostasis
remains unclear.
240 n expansion of tumor-specific CD8(+) T cells
remains unclear.
241 rain structure during early neurodevelopment
remains unclear.
242 nship between lipid metabolism and longevity
remains unclear.
243 replication origin but the association state
remains unclear.
244 zation vary with bioenergy crop species also
remains unclear.
245 The significance of these features
remains unclear.
246 cell will proliferate following Ag encounter
remains unclear.
247 cise role of GR in the pathophysiology of AD
remains unclear.
248 mong these patients in contemporary practice
remains unclear.
249 ter DAA therapy can improve hepatic fibrosis
remains unclear.
250 ease or merely represents a bystander effect
remains unclear.
251 gulated to ensure efficient spindle assembly
remains unclear.
252 by which the UBQLN2 mutations cause disease
remains unclear.
253 nature and drivers of functional adaptation
remain undefined.
254 e and its contribution to disease etiologies
remain undefined.
255 gonadal steroid-sensitive neuronal crosstalk
remains undefined.
256 ving their radiation into diverse ecosystems
remain underexplored.
257 accelerate catalyst development which still
remains underexplored.
258 in meiotic DSB repair, but this process has
remained understudied.
259 HCC surveillance
remains underused in clinical practice, particularly amo
260 ibed associations, many cases of familial WT
remain unexplained.
261 ifferent Galpha proteins with the sole Gbeta
remain unexplored.
262 This possibility
remains unexplored on account of the lack of long-term p
263 ocused on the adult lung, the perinatal lung
remains unexplored.
264 he surface absorption spectra and reactivity
remains unexplored.
265 lved in the activation of many viral strains
remain unidentified.
266 l substrates of ELA-attributable differences
remain unknown due to a paucity of translational investi
267 The sources of these eruptions
remain unknown, but we propose that Mt.
268 ctures present in this heterogeneous pigment
remain unknown, limiting understanding of the properties
269 of nutrient supply regulates chondrogenesis
remain unknown.
270 e durable responses initiated by these drugs
remain unknown.
271 g n-3 PUFAs potential therapeutic properties
remain unknown.
272 HOS status and role of CI mutations in chRCC
remain unknown.
273 nisms leading to product aggregate formation
remain unknown.
274 eristics and drivers of the nMRTF cell state
remain unknown.
275 ough mechanisms explaining this relationship
remain unknown.
276 s outgroup deficit in observational learning
remained unknown, which limits our chances to improve in
277 exact mechanism of GrlA activation, however,
remained unknown.
278 y, the mechanism underlying this association
remained unknown.
279 -Chk1 DNA damage response (DDR) pathways, it
remains unknown how the APE2 gene is altered in the huma
280 However, it
remains unknown whether IRE1alpha adapts the ER in TNBC
281 It
remains unknown whether similar neurophysiological mecha
282 wever, the molecular basis for these effects
remains unknown.
283 ylome on development, homeostasis and stress
remains unknown.
284 observed phenotype change but the mechanism
remains unknown.
285 e of beta-cells to respond to glucose in T2D
remains unknown.
286 functional consequence of CK1alpha mutation
remains unknown.
287 and familial PD upon parkin loss-of-function
remains unknown.
288 s controlled via trans-synaptic interactions
remains unknown.
289 gulatory network that controls oocyte growth
remains unknown.
290 te alphabeta and gammadelta T cell responses
remains unknown.
291 e environmental dependence of most mutations
remains unknown.
292 fleet has been widely documented, its extent
remains unknown.
293 the main opiate receptor of skin mast cells
remains unknown.
294 rce and clinical relevance of the reactivity
remains unknown.
295 or sufficient for cohesion, and its function
remains unknown.
296 n endothelial cells to neuroendocrine tumors
remains unknown.
297 owever, predicting a conserved RNA structure
remains unreliable, even when using a combination of the
298 responsible for its formation and evolution
remain unresolved.
299 ble PCP defects; thus, how Wnts regulate PCP
remains unresolved.
300 29 patients went on to relapse and 38
remained well.