ライフサイエンスコーパス: renal tumor

1 ilms tumor (WT) is the most common pediatric renal tumor.

2 WT-1 expression was observed in the primary renal tumor.

3 atment and more than 2.0-fold in the primary renal tumor.

4 al Ewing's sarcoma (PNET/EES) is a very rare renal tumor.

5 our approach with a case study of a cryptic renal tumor.

6 age, 68.1 years) underwent RF ablation of 15 renal tumors.

7 rwent RF ablation for 26 liver tumors and 17 renal tumors.

8 sion of cyclin D1, a common feature of human renal tumors.

9 protein kinase pathways in brain but not in renal tumors.

10 for diagnosing, characterizing, and staging renal tumors.

11 n an increased detection of incidental small renal tumors.

12 s in 5 families with unilateral and solitary renal tumors.

13 significant uterine fibroids and aggressive renal tumors.

14 rizes current developments in the imaging of renal tumors.

15 t somatic BHD mutations are rare in sporadic renal tumors.

16 r understanding the origins of nonhereditary renal tumors.

17 ere found to be elevated in the TSC2-related renal tumors.

18 I clinical trials for the treatment of small renal tumors.

19 radiofrequency ablation for the treatment of renal tumors.

20 d is not yet widely utilized in the study of renal tumors.

21 iderable interest in the treatment of select renal tumors.

22 is peptide also inhibits the invasiveness of renal tumors.

23 ocation is cytogenetically balanced in these renal tumors.

24 found to develop variable size and number of renal tumors.

25 14.3, an area known to be lost in hereditary renal tumors.

26 months of estrogen treatment and in primary renal tumors.

27 ns from 5 patients with no family history of renal tumors.

28 enal cell carcinoma and no family history of renal tumors.

29 r cell carcinoma), and 10 patients had other renal tumors.

30 eat promise in the differential diagnosis of renal tumors.

31 metastasis and the outgrowth of established renal tumors.

32 e configuration between benign and malignant renal tumors.

33 (ccRCC) and generally not expressed on other renal tumors.

34 een benign oncocytic neoplasia and malignant renal tumors.

35 mental mesenchymal populations and childhood renal tumors.

36 n alphavbeta3 expression and angiogenesis in renal tumors.

37 solitary kidney or in the face of bilateral renal tumors.

38 costs for patients with small (< or = 4-cm) renal tumors.

39 tablished procedure for the treatment of T1a renal tumors.

40 wth and metastasis of tumor cells, including renal tumors.

41 49 and H1975 lung, as well as A498 and 786-O renal tumors.

42 ution and current status of cryoablation for renal tumors.

43 ing of the genetics and molecular biology of renal tumors.

44 FN-gamma secretion by HC/2G-1 in response to renal tumors.

45 nimally invasive nephron-sparing surgery for renal tumors.

46 olipomas; and 16 (8%), other or unclassified renal tumors.

47 has demonstrated variable growth rate among renal tumors.

48 an the past in the preoperative diagnosis of renal tumors.

49 are important advances in the management of renal tumors.

50 afe and effective for the treatment of solid renal tumors.

51 d imaging-guided biopsy in the management of renal tumors.

52 ced to make possible new methods of managing renal tumors.

53 can be effective treatments for select small renal tumors.

54 For this purpose, thirty-three renal tumors (14 renal oncocytic tumors and 19 RCC) were

55 tion was detected in 11 of 39 (28%) sporadic renal tumors: 2 of 7 (29%) renal oncocytomas, 1 of 9 (11

56 forming laparoscopic partial nephrectomy for renal tumors 4-7 cm in size has clearly been demonstrate

57 adult patients with pathologically verified renal tumors: 9 patients with clear cell subtype of the

58 y prevailing methods used for nonextirpative renal tumor ablation.

59 f outcomes prior to routine clinical use for renal tumor ablation.

60 sms mediating the resistance of SMARCB1-null renal tumors against angiogenesis inhibition therapies.

61 ogy of these eight ASPL-TFE3 fusion-positive renal tumors, although overlapping in some aspects that

62 DNA was extracted from 26 renal tumor and paired lymphocyte samples and amplified

63 de expression and regulatory networks of 609 renal tumors and 256 non-tumor renal tissues.

64 A relationship between these renal tumors and ASPS was initially suggested by the cyt

65 tudy also expands the histologic spectrum of renal tumors and FH mutations associated with HLRCC.

66 tatistical modeling allows discrimination of renal tumors and has the potential to be used in the cli

67 -AKT pathway was activated in both human BHD renal tumors and kidney tumors in BHD(d/+) mice.

68 Analyses of ovarian cancers, pediatric renal tumors and multiple breast cancer cell lines showe

69 ged 6 1/2, 7, and 11 years) with adenomatous renal tumors and polycythemia.

70 pression of HIF-alpha subunits in 45 primary renal tumors and related this to tumor subtype, the pres

71 iochemical profiles characteristic of benign renal tumors and renal cancers of different grades.

72 ic biomarkers and therapeutic strategies for renal tumors and renal ischemia.

73 Sensitivity for renal tumors and specificity for renal cysts were establ

74 benign skin tumors, and to a lesser extent, renal tumors and spontaneous pneumothorax.

75 e evaluate the growth of genetically defined renal tumors and their association with patient clinical

76 tatistical modeling allows discrimination of renal tumors and thus has the potential to be used in th

77 ite of metastasis.METHODSWe analyzed primary renal tumors and tumors derived from metastatic sites to

78 s were > 4 cm in diameter, except in lung or renal tumors), and one was treated with alcohol ablation

79 ancers, including ovarian cancers, pediatric renal tumors, and breast cancers.

80 ught new insights into the classification of renal tumors, and may provide new markers that identify

81 promise for the treatment of selected small renal tumors, and MR imaging can be used to monitor the

82 re accurate preoperative clinical staging of renal tumors, and the necessity of completing all the co

83 Here, we review renal tumor angiogenesis and metabolism from a HIF-centr

84 Small renal tumors appear to be similar to larger ones in natu

85 Renal tumors are a family of neoplasms ranging from the

86 Growth kinetics of genetically defined renal tumors are not well known.

87 ivities were directed against a broad set of renal tumor-associated antigens, including telomerase re

88 coming a standard of care for selected small renal tumors at high volume centers.

89 amples, to classify pathological subtypes of renal tumors (benign oncocytoma, clear cell, papillary,

90 ally done with expandable electrodes) of 273 renal tumors between May 2005 and April 2019.

91 ts the expression of integrin alphavbeta3 in renal tumors but represents angiogenesis only when tumor

92 or the minimally invasive treatment of small renal tumors but will remain experimental until the reso

93 Screening for asymptomatic renal tumors by abdominal imaging is not cost-effective

94 g of a ketogenic diet promotes the growth of renal tumors by recruiting ERK1/2 and mTOR which are ass

95 xpectancy of management strategies for small renal tumors by using 1 000 000 simulations in the follo

96 e non-PSA-producing prostate cell line PC-3, renal tumor cell line R11, and cervical adenocarcinoma c

97 Coculture experiments revealed that renal tumor cell lines induced a time-dependent decrease

98 RNA (siRNA) knockdown of Nox4 in 786-0 human renal tumor cells expressing empty vector (PRC) or wild-

99 HIF2-alpha expression and activity in 786-0 renal tumor cells, even in the absence of functional VHL

100 B pathway as a therapeutic strategy to treat renal tumors characterized by biallelic VHL inactivation

101 correlate with PSMA expression in malignant renal tumors compared with benign renal masses, supporti

102 s technique may prove useful for ablation of renal tumors completely in one session, but long-term fo

103 ome with classic "second hits" detectable in renal tumors, conventional genetic analysis has not reve

104 lectively, our data indicate that high-l-2HG renal tumors could be specifically targeted by strategie

105 ce imaging have many indications for imaging renal tumors, CT, with new uses and improved diagnostic

106 The present renal tumor demonstrated morphologic and immunohistochem

107 ic follow-up of radiofrequency ablated small renal tumors demonstrates little or no residual contrast

108 Several lines of evidence, including renal tumors derived from TSC2+/- animals, suggest that

109 mens and in melanoma, leukemia, ovarian, and renal tumor-derived cell lines, suggesting that increase

110 We describe gene expression profiles in 41 renal tumors determined by using DNA microarrays contain

111 xpected number of metachronous contralateral renal tumors developing after an initial diagnosis of RC

112 crossed to p62(-/-) mice were protected from renal tumor development.

113 ress-induced apoptosis and markedly promotes renal tumor development.

114 Twenty-six renal tumors (diameter range, 1.0-4.6 cm; mean, 2.6 cm)

115 c findings in two TSC patients with multiple renal tumors, each of whom had the germline mutation TSC

116 J-BV bladder tumors (EGF+) or human SN12-PM6 renal tumors (EGF-).

117 nimally invasive nephron-sparing surgery for renal tumors encompasses extirpative laparoscopic partia

118 e subtraction enables accurate assessment of renal tumor enhancement, particularly in the setting of

119 of c-fos, was detected in 67% of the primary renal tumors examined, by Southern blot analyses.

120 SMARCB1 wild-type renal tumors exhibited lower levels of SMARCB1 and more

121 Therefore, it was hypothesized that renal tumors express hKIM-1 and release this protein int

122 hown to be localized preferentially in early renal tumor foci after 3.5-4.0 months of estrogen treatm

123 eclin1 almost completely blocked macroscopic renal tumor formation in Tsc2(+/-) mice.

124 for differentiating malignant or aggressive renal tumors from benign or indolent ones, thereby poten

125 ho underwent RF ablation and cryoablation of renal tumors from June 19, 2003, to February 28, 2004, w

126 d MMP-9 were significantly higher in primary renal tumors from patients with either synchronous or me

127 ollected from an additional 42 patients with renal tumors, from 30 normal control subjects, and also

128 nefits of performing partial nephrectomy for renal tumors greater than 4 cm.

129 role of c-Met signaling axis on CNI-induced renal tumor growth and tested the anti-tumor efficacy of

130 k response on AKT Ser473 phosphorylation and renal tumor growth by other phosphoinositide 3-kinase (P

131 Age at diagnosis correlated negatively with renal tumor growth rate (P = .03).

132 In vivo, HNK markedly inhibited CNI-induced renal tumor growth; and it decreased the expression of p

133 Renal tumors had significantly lower ADCs (median, 189.3

134 aging-guided RF ITA for treatment of primary renal tumors has a high success rate.

135 een benign oncocytic neoplasia and malignant renal tumors, highlighting pathways differentially expre

136 xtrapulmonary complications (e.g., malignant renal tumors in Birt-Hogg-Dube syndrome), and surveillan

137 se 4-hydroxyestradiol induces DNA damage and renal tumors in hamsters, and this metabolite is formed

138 Delivery of FGF9 to renal tumors in mice yielded microvessels that were cove

139 uppressor complex have only been reported in renal tumors in patients with the rare Birt-Hogg-Dube sy

140 ppressor gene predispose patients to develop renal tumors in the hamartoma syndrome, Birt-Hogg-Dube (

141 e observed, respectively, for carcinomas and renal tumors in the poorest income quintile.

142 cell proliferation and migration and reduced renal tumors in Tsc2(+/-) mice while reducing PSAT1 expr

143 graft tumors, and development of spontaneous renal tumors in Tsc2(+/-) mice.

144 CNI treatment increased the growth of human renal tumors in vivo, and the expression of CXCR3-B was

145 CNI treatment increased the growth of human renal tumors in vivo, and the Ras-Raf pathway is signifi

146 CsA also promoted the progression of human renal tumors in vivo, wherein VEGF is overexpressed.

147 Most sporadically occurring renal tumors include a functional loss of the tumor supp

148 clustering results of RNA-seq data from 219 renal tumors including 140 rare kidney cancers are large

149 es equivalent oncological results for larger renal tumors including those of 4-7 cm and even for grea

150 Renal tumors invade into large vessels forming tumor thr

151 vailable treatment for patients with a small renal tumor is a form of nephron-sparing tumor excision

152 ing a live donor evaluation in which a small renal tumor is detected, a careful analysis of risk and

153 The management of small renal tumors is changing from radical nephrectomy to nep

154 nt decisions for small incidentally detected renal tumors is cost-effective and can prevent unnecessa

155 50 renal cysts was less than 5%; for the 50 renal tumors, it was 97% or higher.

156 aneous ablation is extremely efficacious for renal tumors; it improves the prognosis of renal carcino

157 ected group of patients with small exophytic renal tumors laparoscopic partial nephrectomy became an

158 omy has become the standard of treatment for renal tumors less than 4 cm in size.

159 For renal tumors less than 4-7 cm (T1 lesions), partial neph

160 s preincubated with the autologous apoptotic renal tumor line in the presence of IFN-alpha.

161 nd beta chains of the HC/2G-1 TCR recognized renal tumor lines, demonstrating that tumor recognition

162 We have also shown that renal tumor lines, including SK-RC-45, induce apoptosis

163 Small renal tumors (<or=3.5 cm) were similar to larger tumors

164 ing kidney donors, the surgical treatment of renal tumors may result in loss of function of the remai

165 Of the 198 renal tumors (median size, 3.4 cm; range, 1.1-20.0 cm) i

166 d with other p120 isoforms, is predictive of renal tumor micrometastasis and systemic progression, fo

167 In the A498 renal tumor model, 7c exhibited superior efficacy over 3

168 othesis by using an estrogen-induced hamster renal tumor model, a well established animal model of ho

169 ibe herein eight morphologically distinctive renal tumors occurring in young people that bear the ide

170 kidney tumorigenesis, we studied 39 sporadic renal tumors of different cell types: 7 renal oncocytoma

171 Growth rates in renal tumors of different sizes, subtypes, and grades re

172 the treatment and outcomes for children with renal tumors on a global level.

173 Published series of growth rates of renal tumors on active surveillance largely consist of t

174 has become a widely accepted option for most renal tumors, open surgery remains the standard in manag

175 Complex partial nephrectomy for multiple renal tumors, or multiplex partial nephrectomy, requires

176 tients with chronic kidney disease and small renal tumors, personalized treatment selection likely ex

177 s were followed up according to our standard renal tumor protocol.

178 inheritance of multiple benign skin lesions, renal tumors, pulmonary blebs, and pneumothoraces.

179 al biogenesis is increased in TSC-associated renal tumors, pulmonary lymphangioleiomyomatosis, kidney

180 enal cell carcinomas (CC-RCCs) but not other renal tumors, raising a question about the importance of

181 Patients with the most common benign renal tumor, renal oncocytomas, may be overtreated with

182 1 literature on pediatric Wilms tumor, other renal tumors, rhabdomyosarcoma of the pelvis, paratestic

183 ogous dendritic cells transfected with total renal tumor RNA have been shown to be potent stimulators

184 studies, as well as primary estrogen-induced renal tumor RNA, for reference.

185 activities against allogeneic tumors because renal tumor RNA-transfected DCs stimulated polyclonal CT

186 Renal tumor RNA-transfected dendritic cells were adminis

187 vement of delivery of care in the setting of renal tumor(s) in a solitary kidney.

188 enetically and histologically different from renal tumors seen in other hereditary renal syndromes an

189 Further, reconstitution of SMARCB1 restored renal tumor sensitivity to hypoxic stress in vitro and i

190 reintroducing chemotherapy in the pediatric renal tumor setting after severe hepatopathy (SH), inclu

191 Thus, patients newly diagnosed with small renal tumors should be referred to centers with expertis

192 grade clear cell carcinomas and sarcomatoid renal tumors) show aberrant expression of cadherin-6, in

193 R imaging-guided percutaneous cryotherapy of renal tumors shows promise for the treatment of selected

194 weight 3.2-kb transcript was observed in the renal tumor, similar to that seen in the newborn mouse k

195 ndard of care for small renal masses, if the renal tumor size and complexity are amenable to such a s

196 HD) patients are uniquely susceptible to all renal tumor subtypes.

197 Complex renal tumors, such as hilar and endophytic lesions, have

198 the entire spectrum of histological types of renal tumors, suggesting its major role in kidney cancer

199 The mechanism of renal tumor suppression by VHL protein is only partly el

200 mechanism by which pVHL protein functions in renal tumor suppression remains unclear.

201 candidate regulatory factor in VHL-mediated renal tumor suppression.

202 ish called NBP which is an ortholog of human renal tumor suppressor Kank.

203 echanism by which VHL protein functions as a renal tumor suppressor remains largely unknown.

204 domain protein Jade-1 (PHF17) is a candidate renal tumor suppressor stabilized by pVHL.

205 ed ccRCC, HIF1alpha has been implicated as a renal tumor suppressor, whereas HIF2alpha is considered

206 Therefore, Jade-1 may be a renal tumor suppressor.

207 res are mimicked in a less common hereditary renal tumor syndrome, known as hereditary leiomyomatosis

208 ive about the management of small, localized renal tumors that are being discovered with increasing f

209 in some cases, caused partial regression of renal tumors that were implanted in the dorsal flank of

210 dings provide a cellular definition of human renal tumors through an approach that is broadly applica

211 ression of CXCR3-B may prevent the growth of renal tumors through the inhibition of antiapoptotic HO-

212 orescence in situ hybridization in all seven renal tumors thus analyzed, which contrasts sharply with

213 in mononuclear leukocytes infiltrating human renal tumor tissue.

214 tissues examined as compared to the matched renal tumor tissues (67%, 1.2-fold to>10-fold, n=18).

215 CD103, the latter significantly enriched in renal tumor tissues.

216 on]; range, 53-92 years), each with a single renal tumor, underwent one percutaneous cryoablation tre

217 e percentage of each immune cell type in 526 renal tumors using the new powerful technique of digital

218 of personalized treatment for small (<=4 cm) renal tumors versus routine partial nephrectomy (PN), ac

219 n-expressing cell line isolated from a mouse renal tumor, was characterized for synthesis, processing

220 ally fused to partner proteins in subsets of renal tumors, we found that wild-type, unfused TFE3 stim

221 lopment or progression of nonproximal tubule renal tumors, we performed a detailed microsatellite all

222 Renal tumors were evaluated for somatic genetic alterati

223 Twenty-six renal tumors were found in the 25 patients.

224 At surgery, 152 renal tumors were identified (77 clear cell, 22 papillar

225 in the exon 11 hotspot, significantly fewer renal tumors were observed in patients with the C-deleti

226 ablished clinical observations, SMARCB1-null renal tumors were refractory to hypoxia-inducing therape

227 rs, when given as single agents, but induced renal tumors, when given together.

228 molecular markers to better characterize all renal tumors will better enable individualized therapy.

229 Renal tumors with c-met genotype show a distinctive papi

230 hereditary renal syndromes and most sporadic renal tumors with papillary architecture.

231 Twenty-five sporadic renal tumors with prominent papillary architecture and w

232 Cryoablation of renal tumors with ultrasound monitoring may be performed

233 ith blood flow, and (d) subcutaneous and (e) renal tumors without blood flow, which was achieved by s