ライフサイエンスコーパス: repeated sequence

1 or example alleles containing transposons or repeated sequences).

2 lt if the repair joins different copies of a repeated sequence.

3 epair, especially when a DSB occurs within a repeated sequence.

4 tutions for adenine at six positions in this repeated sequence.

5 gh both of the solifuges possess a region of repeated sequence.

6 riction of error-prone recombination between repeated sequences.

7 DSB-independent, short deletions at tandemly repeated sequences.

8 ual decrease in RT for nose pokes completing repeated sequences.

9 t process but results in a homogenization of repeated sequences.

10 signal sequence and two conserved regions of repeated sequences.

11 and provide a robust method for dealing with repeated sequences.

12 s consistent with the transcription of short repeated sequences.

13 , resulting in more frequent contractions of repeated sequences.

14 y a remarkable genomic instability at simple repeated sequences.

15 c recombination between Ty elements or other repeated sequences.

16 bers, which bind to both single and tandemly repeated sequences.

17 ntains unprecedented amounts of very similar repeated sequences.

18 fied because they do not bind palindromic or repeated sequences.

19 f the immediate hypomethylation occurring in repeated sequences.

20 a major source of amplification of tandemly repeated sequences.

21 hat are difficult to repair, including other repeated sequences.

22 select for deletions or duplications of the repeated sequences.

23 The 3' region of the cagA gene contains repeated sequences.

24 nd to stimulate recombination between short, repeated sequences.

25 ions known to be mainly composed of tandemly repeated sequences.

26 screened for recombinant plasmids containing repeated sequences.

27 enetic effects, often due to the presence of repeated sequences.

28 by recombination between flanking homologous repeated sequences.

29 C enrichment in both regulatory elements and repeated sequences.

30 effectiveness in handling the complexity of repeated sequences.

31 engaged at collapsed-forks and breaks within repeated sequences.

32 ribonucleotide can compromise BER and RER in repeated sequences.

33 tochondrial genome recombination at numerous repeated sequences.

34 n to occur by recombination between directly repeated sequences.

35 on and can address the methylation status of repeated sequences.

36 lls whose genomes contain numerous divergent repeated sequences.

37 tern consisting of S-shaped distortion, with REPEATED sequences.

38 nt mutation, although most are not currently repeated sequences.

39 half of the mammalian genome is composed of repeated sequences.

40 ely long polypeptide chains with stipulated, repeated sequences.

41 iation and reinvasion occur within dispersed repeated sequences.

42 ed replication protein, TrfA; and A + T-rich repeated sequences, 13-mers, which serve as the initial

43 intron, by homologous recombination between repeated sequences (20-60 bp) abundant in that genome; A

44 A repeated sequence 3' of the DMD regulates imprinted meth

45 Repeated sequences account for 67.2% of the AtDt genome,

46 ficant differences in ADCs among the various repeated sequence acquisitions or the three ROIs.

47 ted by localizing interchromosomal identical repeated sequences along the nuclear genome of the Sacch

48 aracterized by genomic instability at simple repeated sequences, also known as microsatellite instabi

49 Despite repeated sequence analyses, no mutations were found.

50 n of a second chromosome region bounded by a repeated sequence and a telomere, suggesting the dicentr

51 tructural features, including a PEXEL motif, repeated sequences and a C-terminal PHIST domain, and sh

52 t eukaryotes, contain conserved 5'-TTAGGG-3' repeated sequences and are maintained by the action of t

53 ttle is known about the relationship between repeated sequences and deletion formation in mammalian c

54 buted relatively evenly across the length of repeated sequences and detected widespread internal exch

55 DNA, which comprises interspersed and tandem-repeated sequences and exons other than first exons, fro

56 ation followed by misaligned renaturation of repeated sequences and intermolecular pairing of unpaire

57 Despite its numerous repeated sequences and IS elements, the serotype 2 genom

58 This BAC clone lacked highly repeated sequences and mapped to the subtelomeric region

59 age mutations and increase mutation rates in repeated sequences and that there are sequence-specific

60 content, the deletion of several classes of repeated sequences and the introduction of thousands of

61 match repair clearly leads to instability of repeated sequences and to an increased risk for tumorige

62 s, silencing was found to depend strictly on repeated sequences and to correlate with an absence of s

63 e-strand break-induced recombination between repeated sequences, and capture of a chromosome arm by b

64 Complex genomes contain numerous repeated sequences, and genomic duplication is believed

65 ssing Ty1 mobility and recombination between repeated sequences, and one gene (YLR154c) that was not

66 uble-strand break (DSB) formation within the repeated sequences, and that the DSB formation is depend

67 dinucleotide frequencies, the interaction of repeated sequences, and the presence or absence of histo

68 This repeated sequence appears to provide targets for homolog

69 These short repeated sequences, approximately 80, 56, and 71 nucleot

70 Tandemly repeated sequences are a common feature of vertebrate mi

71 Tandemly repeated sequences are a major component of the eukaryot

72 Direct or inverse repeated sequences are important functional features of

73 However, these repeated sequences are notoriously prone to aberrant del

74 nally studied in experimental settings where repeated sequences are present or are being introduced i

75 pression may be silenced epigenetically when repeated sequences are present.

76 In Neurospora crassa, repeated sequences are silenced by repeat-induced point

77 Such repeated sequences are usually short and present at seve

78 bats representing 11 families revealed that repeated sequence arrays near the tRNA-Pro gene are pres

79 enome of trypanosomatids rearranges by using repeated sequences as platforms for amplification or del

80 ty are composites of familiar and unfamiliar repeated sequences as well as what could be considered "

81 ary; 24 of 103 tested (23%) contained highly repeated sequences, as determined by their hybridization

82 The low-frequency repeated sequences at either end of the commonly deleted

83 cate that in addition to the requirement for repeated sequences at the donor and acceptor sites, temp

84 Telomeric DNA - the short, tandemly repeated sequences at the ends of chromosomes - is synth

85 Telomeric DNA consists of short, tandemly repeated sequences at the ends of chromosomes.

86 is dependent on the shortening of telomeres, repeated sequences at the ends of the chromosomes.

87 Recombination between repeated sequences at various loci of the human genome a

88 There is a variety of repeated sequences, both local and dispersed.

89 repair of chromosomal DSBs occurring between repeated sequences by stimulating use of an error-prone

90 A consists of a variable length of the short repeated sequence C1-3A.

91 ur at sites of replication stalling at short repeated sequences capable of forming hairpin structures

92 same novel IS-like element identified by the repeated sequence capture method of Matsutani et al.

93 The repeated sequence CARE2/Rel2 is a subtelomeric repeat on

94 RNAP transcribing templates engineered with repeated sequences carrying imbedded, sequence-specific

95 Both copies of a repeated sequence CATT(A/T), located between bp -53 and

96 ropose that the vast amounts of very similar repeated sequences cause frequent errors in recombinatio

97 An exacerbated genomic instability at simple repeated sequences characterizes cancer of the microsate

98 A remarkable instability at simple repeated sequences characterizes gastrointestinal cancer

99 roteins and their relation to human disease, repeated sequences, comparative genome-wide studies of m

100 saccade and arm motor reaction times for the repeated sequence compared to random sequences.

101 he agr locus; deletions and mutations in the repeated sequences completely abolished the fsrB and gel

102 Methylation is regulated by a repeated sequence, consisting of a 41-mer repeated 40 ti

103 The libraries of human repeated sequences contain the DNA sequences of many TEs

104 and effective repression, arises from highly repeated sequences containing miRNA target sites.

105 a model that shows how pairings between long repeated sequences could be efficiently rejected even th

106 Intact rats that experienced repeated sequences demonstrated robust interference effe

107 o reactions with RNAs containing the GGGGCUG repeated sequence depress splicing of the upstream intro

108 tation of oligomers makes cloning of defined repeated sequences difficult.

109 1 integration frequencies near several human repeated-sequence DNA families, using a repeat-specific

110 d that polypeptides with a -Gly-4(R)-Hyp-Yaa-repeated sequence do not form a triple helix.

111 Misalignment of repeated sequences during DNA replication can lead to de

112 Misalignment of repeated sequences during RecBCD-mediated repair may acc

113 l recombination" between separated, directly repeated sequence elements (>100 bp), events that leave

114 l chromosome ends are interspersed with long repeated sequence elements denoted as long repeated-telo

115 Repeated sequence elements found upstream of the ribosom

116 Repeated sequence elements found upstream of the ribosom

117 Highly repeated sequence elements found within the loops of pre

118 The DNA breaks occur within repeated sequence elements in the linear nuclease-hypers

119 Duplication or expansion of directly repeated sequence elements is associated with a number o

120 Unusual tandemly repeated sequence elements located upstream of H chain g

121 Although repeated sequence elements such as HERVs have the potent

122 in the same fashion, they typically contain repeated sequence elements such as standard promoters an

123 ufficient for replication and contains three repeated sequence elements that are conserved in T.pyrif

124 ns may use either RNA secondary structure or repeated sequence elements to achieve high affinity and

125 Repeated sequence elements were found within the 3'NCR o

126 nscribed regions and frequently occur within repeated sequence elements, including CA repeats, non-CA

127 ted with their content of a number of common repeated sequence elements.

128 whereby they are typically unable to detect repeated sequences embedded within randomly presented st

129 of new cassette exons are composed of highly repeated sequences, especially Alu.

130 eric heterochromatin, where the abundance of repeated sequences exacerbates the risk of ectopic recom

131 tocols: homology-based excision via directly repeated sequences, excision by phage site-specific reco

132 e repeats (TNRs) are highly unstable, as the repeated sequences exhibit a high rate of mutational cha

133 ed domains comprised interspersed and tandem-repeated sequences, exons other than first exons, and no

134 ic region of chromosome 4, relative to other repeated sequence families and single copy sequences, wa

135 ispersion, and evolution of one of the major repeated sequence families of Arabidopsis.

136 findings in yeast that recombination between repeated sequences far apart on the same chromosome may

137 1 to 186) has six glycine-rich repeats of a repeated sequence found in HrpZ, and a purified HrpW har

138 inus of CCA1, which has some homology to the repeated sequence found in the DNA binding domain of Myb

139 Alpha-satellite is a family of tandemly repeated sequences found at all normal human centromeres

140 that replication forks stall at a family of repeated sequences (FR) within the Epstein-Barr virus la

141 When we removed the small regions of repeated sequence from either short or long probes, we f

142 Some of these correspond to highly repeated sequences from either duplicated endogenous gen

143 ng method is not significantly influenced by repeated sequences, genome size, and genome complexity.

144 (TAS), which consists of a mosaic of complex repeated sequences, has been identified as a source of g

145 ps and their elevated mutation rates, tandem repeated sequences have the potential to influence splic

146 fied in humans are flanked by short directly repeated sequences; however, mechanisms by which these d

147 ng human L1 elements to study methylation of repeated sequences, (i) we distinguish valid L1 sequence

148 chanism for deletion and/or amplification of repeated sequence in both prokaryotic and eukaryotic gen

149 L1 is a ubiquitous interspersed repeated sequence in mammals that achieved its high copy

150 Here we show that a repeated sequence in the cytoplasmic tail of synaptophys

151 is transcript revealed a cluster of tandemly repeated sequence in the human, orangutan, and chimpanze

152 ring sites, which consist mostly of a 240-bp repeated sequence in the intergenic spacers (IGS) of the

153 bp mitochondrial DNA (mtDNA) D-loop tandemly repeated sequence in the populations of a North American

154 gnment of the nascent strand relative to the repeated sequence in the template strand accomplishes th

155 tion in the de novo methylation of dispersed repeated sequences in a premeiotic genome scanning proce

156 patible with the presence of large arrays of repeated sequences in cloned DNA.

157 m both a higher number of repeats and larger repeated sequences in comparison to eight other angiospe

158 t mutation in Neurospora crassa and A:T-rich repeated sequences in heterochromatin in other organisms

159 ry that a large number of loci with tandemly repeated sequences in human and many eukaryote species a

160 ir are important in the somatic expansion of repeated sequences in mouse models of trinucleotide repe

161 osatellite expansion disorders, expansion of repeated sequences in noncoding regions gives rise to RN

162 Further, the abundance of repeated sequences in plant genomes requires that crossi

163 vercome the inherent difficulty of annealing repeated sequences in register.

164 y of ectopic recombination between naturally repeated sequences in S. pombe.

165 r GC skews and the presence of ISs and large repeated sequences in the AY-WB and OY-M genomes are ind

166 into the mechanism of recombination between repeated sequences in the context of replication stress,

167 In our studies of repeated sequences in the genome of the marine shrimp, P

168 Host defense mechanisms monitor repeated sequences in the genome, modulating their chrom

169 logous recombination in yeast between common repeated sequences in the targeted chromosomal fragment.

170 Template jumping also occurs between repeated sequences in the Tomato and green fluorescent p

171 The R751 genome reveals a family of repeated sequences in these regions which may form the b

172 a rationale for the extensive repertoire of repeated sequences in this genome.

173 The instability of repeated sequences in this strain may be linked to the l

174 ed for this purpose, we searched for various repeated sequences including inverted, direct tandem, an

175 the pattern of methylation of several highly repeated sequences including the rDNA arrays, a Y-specif

176 Detailed analyses of repeated sequences indicate that many of the Glycine rep

177 wo examples were control of transcription by repeated sequence inserts in sea urchin genomes.

178 mid-based recombination assay to investigate repeated sequence instability in human cells.

179 location and DNA sequence divided the seven repeated sequences into two classes.

180 mitochondrial DNAs is the presence of large repeated sequences involved in intramolecular and interm

181 which suggests that hairpin formation in the repeated sequence is disrupted.

182 lity and that the secondary structure of the repeated sequence is disrupted.

183 ous recombination occurring among misaligned repeated sequences is a significant source of the molecu

184 s proteolytic maturation in which any of six repeated sequences is cleaved by the nutrient-responsive

185 ion patterns on the complementary strands of repeated sequences is difficult using standard bisulfite

186 Homologous recombination between dispersed repeated sequences is important in shaping eukaryotic ge

187 leting multiple nucleotides between directly repeated sequences is reduced by approximately 10-fold i

188 ed with a transgene locus containing several repeated sequences is undesirable.

189 ed by single nucleotide polymorphisms, short repeated sequences known as short tandem repeats (STRs),

190 troduce erroneous spliced alignments between repeated sequences, leading to the inclusion of falsely

191 by negative regulation of DNA methylation at repeated sequences, linking to telomere maintenance and

192 The NT4 repeated sequence LKTEN was highly homologous with a sit

193 ple inputs; these include the interaction of repeated sequences, local states of histone lysine methy

194 We analyzed rearrangements mediated by repeated sequences located in different chromosomes.

195 RNA targets for these proteins include short repeated sequences, longer single-stranded sequences, RN

196 marked changes resulted in demethylation of repeated sequences, loss of insulin-like growth factor I

197 ssion of rearrangements involving divergent, repeated sequences may underlie the genome instability s

198 arently due to the copy number of a 135-base repeated sequence, may be the cause of the differential

199 eta-actin mRNA, Vera specifically binds to a repeated sequence motif in the Vg1 localization element

200 ber of a diverse protein family defined by a repeated sequence motif known as the KEL repeat (KREP).

201 Instead, it contains a repeated sequence motif similar to a regulatory element

202 disordering amino acid proline, they contain repeated sequence motifs and extensive posttranslational

203 lar numbers of genes, with abundant tandemly repeated sequence motifs, and transposable elements alon

204 at intrinsic DNA features, such as complexed repeated sequence motifs, predispose the human genome to

205 o tested peptides we created that included 3 repeated sequence motifs.

206 s of G(i)-like G proteins contain homologous repeated sequences named G protein regulatory (GPR) moti

207 a mechanism for metabolic regulation, since repeated sequences nucleate heterochromatin formation in

208 ose that rearrangements between short tandem repeated sequences occur by errors made during a replica

209 We hypothesize that polymorphisms in repeated sequences occur with some baseline distribution

210 f collagen is the triple helix formed by the repeated sequence of -Gly-Xaa-Yaa-.

211 line in the Yaa position of the -Gly-Xaa-Yaa-repeated sequence of collagen plays a crucial role in th

212 Mice were trained to respond to changes in a repeated sequence of natural images while neural activit

213 ington's disease is caused by expansion of a repeated sequence of the amino acid glutamine in the abn

214 ht healthy subjects listening passively to a repeated sequence of unrelated words.

215 Short tandem repeats (STRs) consist of repeated sequences of 1-6 bp and comprise >1 million loc

216 ain, typically eliminating five of the seven repeated sequences of 20 amino acids (aa) each in the ce

217 aa in length at its N-terminal end, and four repeated sequences of about 34 aa at its C-terminal end.

218 ates that LGN is a mosaic protein with seven repeated sequences of about 40 aa in length at its N-ter

219 Long repeated sequences of DNA and their associated secondary

220 Recently, it has been shown that short, repeated sequences of intermittent ischemia and reperfus

221 Repeated sequences of neural activity are a pervasive fe

222 iefly, the task involves the presentation of repeated sequences of odors at a single port and require

223 ntramolecular recombination between tandemly repeated sequences of rho(-) mtDNA to produce small, cir

224 Further, we found evidence of repeated sequences of site visitation in all species, su

225 ated template-matching algorithm to identify repeated sequences of syllables and a modified dynamic t

226 ed and recorded, determining variants within repeated sequences of the human genome remains a challen

227 t Cdc4, which is an F-box protein containing repeated sequences of WD40 (a unit containing about 40 r

228 The repeated sequencing of bacterially-cloned fragments of p

229 d approaches in Clostridium difficile, using repeated sequencing of the same isolates (replicates) an

230 l repair of double-strand breaks in tandemly repeated sequences often results in the loss of one or m

231 s recombination (NAHR), mediated by flanking repeated sequences or segmental duplications.

232 Large blocks of tandemly repeated sequences, or satellites, surround the centrome

233 ribosomal DNA tend to be formed of high copy repeated sequences organized in tandem arrays.

234 ther speculation about the role these highly repeated sequences play in centromere identification.

235 ParB bound in vitro to repeated sequences present in a region, parS, that posse

236 centromeric heterochromatin mostly comprises repeated sequences prone to aberrant recombination.

237 essing recombination in Arabidopsis at every repeated sequence ranging in size from 108 to 556 bp.

238 the chromosome of this bacterium is a set of repeated sequences related to msDNA.

239 array, a genomic locus consisting of short, repeated sequences ('repeats') interspersed with short,

240 vegetative cells of fungi are undefined, but repeated sequences seem particularly susceptible to thes

241 (e.g., common fragile sites, telomeres, and repeated sequences), selectively promotes homology-drive

242 Repeated sequences serve as donor and acceptor templates

243 BatC and BatE contain 2-4 repeated sequences similar to the tetratricopeptide repe

244 Highly repeated sequences smaller than 100 nt have been describ

245 umerary B chromosome were determined using a repeated sequence specific to the centric region.

246 Over 50% of the genome consists of repeated sequences, such as retrotransposons and genes f

247 ctures and several unusual sets of conserved repeated sequences suggesting novel regulatory systems f

248 RVFVmiR-142 includes an insertion of four repeated sequences targeted by hematopoietic-specific mi

249 The egg receptor for lysin is a tandemly repeated sequence that evolves by concerted evolution.

250 he intervening D(H)s form part of a tandemly repeated sequence that expresses tissue-specific, antise

251 These similarities include a repeated sequence that forms the basis of the reiterated

252 GlnR binding site includes four copies of a repeated sequence that may be the recognition site for t

253 Ribosomal DNA (rDNA) consists of highly repeated sequences that are prone to incurring damage.

254 belements of the silencer include five short repeated sequences that are required for Tra2 binding bu

255 oteins containing short lysine-rich tandemly repeated sequences that are sufficient to localize to th

256 Telomeres consist of short repeated sequences that are synthesized by telomerase, a

257 east in part, of relatively short modules of repeated sequences that are the source of insertion-dele

258 telomeres of most organisms consist of short repeated sequences that can be elongated by telomerase,

259 d endonuclease (VDE) and flanked by directly repeated sequences that can be used for intrachromatid s

260 ombination events between the abundant short repeated sequences that characterize the genomes of high

261 verse-transcribing genetic elements, require repeated sequences (the donor and acceptor sites) betwee

262 If heterologies are present between repeated sequences, the mismatch repair system dependent

263 'regional' centromeres embedded in tandemly repeated sequences to holocentromeres that extend along

264 s of rearranged gene clusters are flanked by repeated sequences, tRNAs, or pseudogenes.

265 Deletion analysis has shown that a repeated sequence, TTTTGAT, is required for ToxR binding

266 merase, telomeric DNA, is typically a G-rich repeated sequence, (TTTTGGGG)(n) in the ciliate Euplotes

267 e well-studied BimA protein, and found short repeated sequences unique to Burkholderia species, as we

268 e origin of the unique regions bordering the repeated sequence was located in the expected chromosome

269 amplification technique that creates tandem repeated sequences, was used in combination with a fluor

270 for the structural analysis of DNA in mirror-repeated sequences we modified a conventional protocol.

271 ng the genetic loci containing the conserved repeated sequences, we have characterized a prtP gene ho

272 Whereas dispersed repeated sequences were demethylated in mutant germ cell

273 tion experiments, it was concluded that both repeated sequences were essential for specific protein b

274 gions of extensive divergence that contained repeated sequences were found 3' to this conserved regio

275 MR imaging time and examinations with repeated sequences were recorded.

276 The directly repeated sequences were upstream of the polypurine tract

277 cal for TR2-11-f binding were mapped to both repeated sequences, whereas the spacer and the flanking

278 e more effectively resolves conflicts due to repeated sequences which is the main difficulty of the s

279 oth cases phiRv1 is inserted into a REP13E12 repeated sequence, which presumably contains the bacteri

280 The STT contained a repeated sequence, which was interleaved with random seq

281 This repeated sequence, which we refer to as the upstream hom

282 merous copies of the (TTAGGG)(n).(AATCCC)(n) repeated sequence with multiple TTAGGG repeats in 3' sin

283 Repeated sequences with >100 base pair lengths occupy mo

284 generated by recombination between pairs of repeated sequences with high identity.

285 ng the ribosomal DNA (rDNA), are composed of repeated sequences with well-defined copy numbers that m

286 Integration occurred before or after the repeated sequence, with one integration site between the

287 site-directed mutations to identify directly repeated sequences within attN1 that were required for s

288 Only the repeated sequences within DMD2 were required for imprint

289 We find that very short (e.g. 20 nt) perfect repeated sequences within much longer probes (e.g. 350-1

290 Each of the 20 repeated sequences within the FR contains a binding site

291 Genome assembly is difficult due to repeated sequences within the genome, which create ambig

292 The distribution of these repeated sequences within the karyotype of this species,

293 This study describes two tandemly repeated sequences within the Leishmania genome that all

294 mutation correlates with DNA methylation and repeated sequences within the loci, recent experiments a

295 at the strand junction profoundly influences repeated sequences within three-way junctions.

296 e, pairings between different copies of long repeated sequences would usually become irreversible.

297 Nup475 contains two tandemly repeated sequences YKTELCX8CX5CX3H (Cys3His repeats) tha