ライフサイエンスコーパス: repetitive

1 ton conductance and high fidelity in driving repetitive action potentials in neurons.

2 sed reports of dream movement, especially of repetitive actions.

3 n(2+) inhibition is significant during rapid repetitive activity with pulses of millimolar concentrat

4 citatory currents that depress deeply during repetitive activity, driving phasic spike output.

5 ore complex mechanisms capable of sustaining repetitive activity, overcoming inhibitory mechanisms th

6 demonstrate that in diabetic animal strains repetitive ambient ozone exposure led to early and exagg

7 Quantification of enrichment for repetitive and abundant multicopy elements reveals 70% o

8 MG) development is controlled locally by the repetitive and bi-directional cross-talk between the epi

9 wheat genome are shaped by the interplay of repetitive and gene-encoding regions that are predictive

10 However, because of its repetitive and haploid nature, it is frequently absent f

11 ole that is evident at forks traversing both repetitive and non-repetitive DNA, though it becomes cru

12 behaviours (SIBs) are defined as deliberate, repetitive and persistent behaviours that are directed t

13 induced generalized seizures, hyperactivity, repetitive and reduced anxiety behaviours, plus several

14 n gray matter ROIs correlated with increased repetitive and restricted behaviors and poor social inte

15 studies demonstrating exposure to both mild-repetitive and severe TBIs are linked to tau depositions

16 is an elongate and segmented bilaterian with repetitive and trilobate body units, each of which consi

17 one of 70 (1%) for diagnostic, quantitative, repetitive, and explorative tasks, respectively.

18 hat the effect of NMES on BP was dampened by repetitive anesthesia.

19 How repetitive antigenic stimulation impairs T cell self-ren

20 ase that underscores affinity enhancement by repetitive arrangement of disaccharide units.

21 matic spatial assemblies of the well-ordered repetitive arrays of transcription units.

22 iguously extract DNA methylation patterns of repetitive, as well as single genetic loci from pure cel

23 Repetitive AVA firing and reversals require EGL-30/Galph

24 Initially, PCR methods targeted the 35-fold repetitive B1 gene, and more recently, coding sequence R

25 ater samples via cloud point extraction on a repetitive basis.

26 e secondary endpoints, oxytocin reduced ADOS repetitive behavior (2.0 to 1.5; P < .0001) compared wit

27 D1-MSN specific translatome associated with repetitive behavior by using RNA sequencing of ribosome-

28 icity (L-LTP), and potentiates perseverative/repetitive behavior in mice.

29 /neuritogenic pathways, concurrently causing repetitive behavior, social deficits, and synaptic dysfu

30 impaired social communication and restricted repetitive behavior.

31 suggests oxytocin's possibility to treat ASD repetitive behavior.

32 ss in dorsal striatum D1-MSNs from mice with repetitive behavior.

33 in microglia reproduced social deficits and repetitive behavior.

34 mission and influences social preference and repetitive behavior.

35 mgl-2 loss blocks oscillations and repetitive behavior; while RIM activation is sufficient

36 ntly associated with tics in humans and with repetitive behavioral pathology in mice, making it a pla

37 ee sites reliably observed a hyperactive and repetitive behavioral phenotype in KO rats compared to t

38 aking and has been implicated in restricted, repetitive behaviors (RRB) in autism spectrum disorder (

39 C during pregnancy shows abnormal social and repetitive behaviors and elevated striatal dopamine, a m

40 itory neurons in the hippocampus, as well as repetitive behaviors and impairments in novelty interest

41 , rigid personality was related to increased repetitive behaviors in children.

42 paired synaptic transmission and ameliorated repetitive behaviors in these mice.

43 /CMKII) displayed increased anxiety-like and repetitive behaviors that were both restored by chronic,

44 ruptions in social behavior and increases in repetitive behaviors that were larger in males than in f

45 D, including impaired social interaction and repetitive behaviors, and reduced brain network activiti

46 Autism is characterized by repetitive behaviors, impaired social interactions, and

47 In addition, Kdm5a(-/-) mice displayed repetitive behaviors, sociability deficits, cognitive dy

48 of this circuit induced social deficits and repetitive behaviors, whereas activation of Purkinje cel

49 l interaction and communication deficits and repetitive behaviors.

50 n individuals spending more time engaging in repetitive behaviors.

51 social motivation, and restricted interests/repetitive behaviors.

52 cial interactions, restricted interests, and repetitive behaviors.

53 n of impairments in social communication and repetitive behaviours, highly restricted interests and/o

54 inhibition, impulsivity, loss of empathy and repetitive behaviours.

55 The mortality rates in patients with repetitive bleeding, repetitive MI, and both bleeding an

56 Here, we explore the effect of delayed and repetitive boosting of RV144 vaccine recipients with AID

57 Repetitive, but not single blast exposure, induced delay

58 nces (up to 150 frames/s) to be analyzed and repetitive Ca(2+) events (Ca(2+) sparks and Ca(2+) puffs

59 ated the relationship between P2Y-stimulated repetitive Ca(2+) waves and fibrinogen binding to the pl

60 uction of a switchable magnetic trap enables repetitive capture and release of magnetic particles for

61 roallergen-induced experimental asthma using repetitive cat dander extract exposure.

62 engineering, but their use is limited by the repetitive centromeric alpha-satellite DNA needed to for

63 eosome seeding strategy, a construct lacking repetitive centromeric DNA formed several self-sufficien

64 deleterious meiotic recombination events at repetitive centromeric sequences.

65 nt disorder characterized by involuntary and repetitive co-contractions of agonist and antagonist mus

66 Although repetitive, cognate TCR signaling is recognized as the p

67 cal examination was delayed relaxation after repetitive contractions.

68 zed by compulsive drug seeking, and involves repetitive cycles of compulsive drug use, abstinence, an

69 G4 unwinding mediated by Rep involves repetitive cycles of G4 unfolding and refolding fueled b

70 ral integrity and detection capability under repetitive deformations, including bending and twisting.

71 costriatal functioning we recorded increased repetitive digging behavior and decreased sociability.

72 he unconverted rate (UCR) by using telomeric repetitive DNA as native spike-in control.

73 Here we show that repetitive DNA becomes de-repressed more rapidly in old

74 es disrupt heterochromatin, transcription of repetitive DNA elements and subsequent processing of the

75 These highly repetitive DNA elements pose a risk to genome stability

76 SUV420H2-bound regions are enriched with repetitive DNA elements, which are de-repressed in SUV42

77 terrogates the binding of >1000 human TFs to repetitive DNA elements, while the second evaluates TF b

78 erochromatin formation and the repression of repetitive DNA elements.

79 ric heterochromatin is generally composed of repetitive DNA forming a transcriptionally repressive en

80 We find that clustering of repetitive DNA loci into chromocenters takes place in a

81 We propose that the repetitive DNA sequence of the PAR confers unique chroma

82 Centromeres are built on repetitive DNA sequences (CenDNA) and a specific chromat

83 Repetitive DNA sequences are often associated with chrom

84 The human genome is replete with repetitive DNA sequences that can fold into thermodynami

85 These long stretches of repetitive DNA vary in length among human chromosomes.

86 Heterochromatin suppresses repetitive DNA, and a loss of heterochromatin has been o

87 Half the Ot genome is composed of repetitive DNA, and there is minimal collinearity in gen

88 ~ 12-30 Gbp), which also consist of ~ 80% of repetitive DNA, is a very complex and computationally in

89 at forks traversing both repetitive and non-repetitive DNA, though it becomes crucial at long CAG re

90 alized chromatin marked by CENP-A wrapped by repetitive DNA.

91 enes and drives recombination in a region of repetitive DNA.

92 ploid species with pronounced improvement in repetitive-DNA-enriched centromeric regions.

93 ies to reduce relapse.SIGNIFICANCE STATEMENT Repetitive drug use induces synaptic plasticity that und

94 We report a sensitive PCR-based assay called Repetitive Element AneupLoidy Sequencing System (RealSeq

95 P-43 and redistribution of TDP-43 binding to repetitive element transcripts and mRNAs encoding mitoti

96 Repetitive element transcripts could be detected in hemo

97 f this strain (NHDP-385) identified a unique repetitive element, RLPM, on which a specific real-time

98 Repetitive elements (REs) compose ~50% of the human geno

99 f many non-coding RNAs (ncRNAs) generated by repetitive elements and their connection with pathologic

100 3K9-methylated heterochromatin helps silence repetitive elements and tissue-specific genes.

101 en songbird species and contain a variety of repetitive elements and unique sequences with paralogs i

102 associated with a loss of heterochromatin at repetitive elements during ageing in male flies, and a g

103 Indeed, ectopic expression of repetitive elements enhanced HSPC formation in wild-type

104 ral role for H1 linker histones in silencing repetitive elements in mouse embryonic stem cells.

105 tier of genome editing and enable editing of repetitive elements of mammalian genomes, we made use of

106 ngth of introns flanking circularized exons, repetitive elements such as Alu elements and SINEs, comp

107 th siRNAs from transposons and newly evolved repetitive elements that are packaged in EVs and release

108 Thus, repetitive elements transcribed during development drive

109 changes, e.g. tracts of homozygosity (TOH), repetitive elements, and insertion/deletions, may provid

110 We identified incomplete DNA methylation of repetitive elements, associated with specific genomic co

111 How repetitive elements, epigenetic modifications, and archi

112 alf of the assembled sequence is composed of repetitive elements, which are enriched within recombina

113 We used a set of gRNAs targeting repetitive elements-ranging in target copy number from a

114 el insight into the evolutionary dynamics of repetitive elements.

115 tention at inter- and intragenic regions and repetitive elements.

116 ctorial, fibroinflammatory syndrome in which repetitive episodes of pancreatic inflammation lead to e

117 girl was referred to our hospital because of repetitive episodes of urticaria when she consumed pork

118 med event correlation microscopy that aligns repetitive events with respect to the high time-resoluti

119 d on changes in local activity levels during repetitive executions of a task.

120 r H3K9me3 deposition over LINE-1 repeats and repetitive exons in transcribed genes.

121 cific repeat elements; the promoter; and non-repetitive exons, as well as the entire XIST gene, were

122 orming long-term memory (LTM) often requires repetitive experience spread over time.

123 and their genetic diversity was measured by repetitive extragenic palindromic (REP)-PCR fingerprinti

124 We show that in both regions, repetitive firing parameters increase and excitability d

125 ibition in pvBCs after a spike and inhibited repetitive firing.

126 1 channels homeostatically reduce motoneuron repetitive firing.

127 ty, Kv2.1 channels homeostatically reduce MN repetitive firing.

128 rolong action potential duration and enhance repetitive firing.

129 increase in Na(V)1.8 surface expression and repetitive firing.

130 AP latency and jitter during high frequency repetitive firing.

131 ped and characterized a habituation assay to repetitive footshocks in mixed sex Drosophila groups and

132 y of complex and native antigens in a highly repetitive form on their surface and can easily reach ly

133 A repetitive GAA motif was identified to be an exonic spli

134 ain oncogenic viruses activate expression of repetitive genes called retrotransposons, which are norm

135 lity de novo assembly is possible for large, repetitive genomes.

136 in understanding trait differences in highly repetitive genomes.

137 The occurrence of repetitive genomic changes that provide a selective grow

138 of genes, transposable elements, and highly repetitive genomic features such as telomeres, heterochr

139 topologically associating domains involving repetitive genomic regions, thereby unlocking a previous

140 mitations in detecting insertions in complex repetitive genomic regions.

141 ted TE insertions frequently found in highly repetitive genomic regions.

142 guarantee is lost and accuracy is reduced in repetitive genomic regions.

143 s HUSH assembly and epigenetic regulation of repetitive genomic targets.

144 Repetitive glutamate release and reversal behavior requi

145 crumb is mainly made up by protein from non-repetitive gluten domains.

146 d by the release by Aq1 of peptides from the repetitive gluten protein domains during baking.

147 Repetitive head impacts (RHI) are a growing concern due

148 generative tauopathy that is associated with repetitive head impacts or exposure to blast waves.

149 n athletes and military personnel exposed to repetitive head impacts.

150 egenerative disorder that is associated with repetitive head impacts.

151 attention because of possible links between repetitive head injury and neurodegenerative diseases.

152 domain (CTD) of RNA polymerase II contains a repetitive heptad sequence (YSPTSPS) whose phosphorylati

153 calyx of Held terminals of either sex during repetitive high-frequency spiking.

154 Repetitive hind limb ischemia in rats-blood plasma trans

155 evaluated the immune response as a result of repetitive, homologous immunization using BALB/c mice.

156 Further enrichment by repetitive HPLC fractionation resulted in the quantitati

157 rk operates in single human cells to process repetitive IFN stimulation.

158 Thus, we propose that repetitive IgH switch regions represent favored substrat

159 a biotinylated synthetic peptide comprising repetitive immunogenic gluten motifs.

160 A components of ribosomes (rRNA), are highly repetitive in all eukaryotic genomes, containing 100s to

161 ared mouse and human AD brains combined with repetitive in vivo two-photon imaging showed focal fibri

162 s improved social preference impairments and repetitive/inflexible behaviors, respectively, in male P

163 PFC mediates cerebellum-regulated social and repetitive/inflexible behaviors; and showed disruptions

164 ors for idiopathic pulmonary fibrosis, where repetitive injury to the alveolar epithelium is consider

165 rticles trigger anti-apoptotic pathway after repetitive intravenous administrations in mice.

166 Because LINE-1 elements are repetitive, it is difficult to quantify LINE-1 RNA at sp

167 Our qPCR assay utilized repetitive LINE-1 elements specific to the genome of Sus

168 d from major complications of WRS, including repetitive liver failure episodes and poorly controlled

169 that the glomerular network does not form by repetitive longitudinal splitting of capillaries.

170 fied biomarker signatures in rats exposed to repetitive low-level blast that develop chronic anxiety-

171 Rats exposed to repetitive low-level blasts accumulated abnormal hyperph

172 minant repressive mechanism for silencing of repetitive major satellite sequences.

173 an follow the same host-guest complex during repetitive mechanical measurements, however, mechanical

174 rates in patients with repetitive bleeding, repetitive MI, and both bleeding and MI were 16.1%, 19.2

175 pathy (CTE) in particular is associated with repetitive mild TBI (mTBI) and is characterized patholog

176 Repetitive mild traumatic brain injury in American footb

177 While the mechanisms underlying repetitive mild traumatic brain injury-induced neurodege

178 Therefore, it is important to determine if repetitive, mild TBI (rmTBI) will also disrupt the gut m

179 itive patients' blood by serial dilution and repetitive mitogen stimulation.

180 The data suggest that the dominant and repetitive mode of DNA opening of the helicase can be us

181 Male C57BL/6J mice underwent repetitive moderate brain injury (rmdTBI) or sham injury

182 t neuropsychiatric disorder characterized by repetitive motor movements and vocal tics.

183 Tics are involuntary, repetitive movements and vocalizations that occur in bou

184 gnition, and/or memory deteriorate following repetitive mTBI.

185 By use of a novel human repetitive nasal allergen challenge (RAC) model, we eval

186 Novel repetitive nasal allergen challenge in participants with

187 However, the highly repetitive nature of the LRP reporter gene sequence lead

188 of behaviours linked by their reward-based, repetitive natures.

189 onfirmed by positive edrophonium or abnormal repetitive nerve stimulation, or abnormal single fibre e

190 ecific short-amplicon ddPCR assays targeting repetitive nuclear genomic elements (LINE-1) and mitocho

191 high incidence of nuclear bleb formation and repetitive nuclear ruptures, which promoted nuclear effl

192 Following repetitive O3 exposure, higher bronchoalveolar lavage fl

193 ARPin-bound at pH 7.4) in which the combined repetitive oligopeptides (CROPS) domain points away from

194 Toxin A (rARU, also known as CROPS [combined repetitive oligopeptides]) C-terminal region, was shown

195 Here, we show that repetitive optogenetic stimulation confined to cholinerg

196 hasing of structural variants, especially in repetitive or homologous regions, can be problematic due

197 subjects in the chronic stage following mild-repetitive or severe TBI and 15 healthy control subjects

198 ission exhibits high fidelity in response to repetitive OSN input.

199 animals were exposed to filtered air (FA) or repetitive ozone (0.5 ppm O3, 4 h/d, for 13 consecutive

200 to determine whether pulmonary responses to repetitive ozone exposures are exacerbated in murine str

201 nd rapid photodegradation is used to achieve repetitive passaging of stem cell colonies without loss

202 fluctuations in shear rate, occuring during repetitive passive stretching adminstration (passive str

203 Interestingly, we find a repetitive pattern of gene activity in progressive state

204 ectral-domain are known as complex and a non-repetitive phenomenon with the time scale from nanosecon

205 l progress has been made on the synthesis of repetitive polyketide motifs through the iterative appli

206 ax, besides having variations in the protein repetitive portion, can differ from each other in aspect

207 braries onto an agarose bead support enables repetitive primer extension assays for specific genomic

208 role of an intrinsically disordered protein, REPETITIVE PRO-RICH PROTEIN (RePRP), in regulating rice

209 oarse-grained representations while avoiding repetitive procedures such as ad hoc back-mapping from c

210 A family of repetitive proline-rich proteins interact with acidic pe

211 Spider silk spidroins consist of long repetitive protein strands, flanked by globular terminal

212 for the in vitro seamless assembly of large repetitive proteins with biotechnological relevance.

213 We hypothesize that repetitive PRPs interact with acidic pectins to form blo

214 Repetitive pulmonary injury causes fibrosis and inflamma

215 Software was categorized by task (repetitive, quantitative, explorative, and diagnostic),

216 ts combined with optical modelling show that repetitive re-absorption and re-emission of photons trap

217 d hence underestimate biological signal from repetitive regions of genomes.

218 igate the chromatin states of the coding and repetitive regions of the allopolyploid wheat genome.

219 romatin remodeler with roles in silencing of repetitive regions of the genome and in recruitment of t

220 The ability to characterize repetitive regions of the human genome is limited by the

221 o accurately quantify the activity of highly repetitive regions of the human genome.

222 variant detection by locating breakpoints in repetitive regions.

223 ircles from unique regions of the genome and repetitive regions: rDNA and telomeric Y' regions.

224 Repetitive REs switching repeat classes during different

225 lasticity, the facilitation or depression of repetitive responses.

226 while RIM activation is sufficient to induce repetitive reversals in glt-1 mutants.

227 y of each arginine side chain even in highly repetitive RGG amino acid sequence motifs found in numer

228 The repetitive RNA derived from the C9 repeat is known to se

229 Surprisingly, repetitive RNA loci expression remained unaltered follow

230 The expansion is transcribed into a long repetitive RNA, which negatively sequesters RNA-binding

231 e-flTrkB) in which a subset of animals shows repetitive rotations and head tics with juvenile onset.

232 In RNA sequencing of repetitive samples from the hollow fiber system and in i

233 In contrast, Treg cells adopt a confined, repetitive-scanning motility while contacting APCs.

234 itted in response to social cues with robust repetitive self-grooming behaviors relative to saline tr

235 Finally, lithium treatment ameliorated a repetitive self-grooming phenotype in Shank3 knockout mi

236 nt statistics by reducing brain responses to repetitive sensory information is key for efficient info

237 volving subtelomere - the telomere-adjacent, repetitive sequence - is a primary driver of the 'telome

238 ompanied by decreased H3K9 trimethylation of repetitive sequence chromatin.

239 se results suggest that pervasive intergenic repetitive sequence expression during human spermatogene

240 mina approaches reveal only a portion of the repetitive sequence landscape of eukaryotic genomes and

241 Activation of repetitive sequence transcription is accompanied by decr

242 Molecular typing was done by repetitive-sequence PCR to define distinct S aureus stra

243 Although repetitive sequences are enriched in H3K9me2 and linker

244 Toxic RNAs expressed from such repetitive sequences can be eliminated using CRISPR-medi

245 istinctive features of transposons and other repetitive sequences in Marchantia compared with floweri

246 space complexity for detecting most types of repetitive sequences in multiple scenarios, including fi

247 Although highly diverse, their repetitive sequences induce DNA polymerase slippage and

248 Repetitive sequences such as satellite DNAs are potentia

249 a large sex chromosome composed primarily of repetitive sequences with a large number of Copia and Gy

250 ffsets aberrant behavior caused by excessive repetitive sequences without compromising its targeting

251 annotations (e.g., transposable elements and repetitive sequences).

252 profound de-repression of several classes of repetitive sequences, including major satellite, LINE-1,

253 Transcribed genomic repetitive sequences, including simple centromeric repea

254 % of mouse and human genomes are composed of repetitive sequences.

255 to failure when their genetic parts contain repetitive sequences.

256 HPV-EM, to address the ambiguities caused by repetitive sequencing reads.

257 overable structural failure arising from the repetitive severe volume change during lithium-sulfur ba

258 intraretinal, and subretinal stresses during repetitive shaking.

259 ar to the plane of hexagonal lattices prompt repetitive shear-like deformations of the solitons, whic

260 The repetitive size change of the electrode over cycles, ter

261 inefficient, relying upon harsh conditions, repetitive steps, and ligands with only modest selectivi

262 or the salient features of autism, including repetitive stereotyped behaviors (self-grooming and marb

263 onding to greater sustained responses during repetitive stimulation, despite a reduction in the measu

264 Finally, after just 2 min (~10%) of repetitive stimulation, we were able to predict poststim

265 abling duration-dependent desensitization to repetitive stimulations.

266 al mechanisms are needed to sometimes ignore repetitive stimuli (e.g., the tic of a clock) or detect

267 However, repetitive stimuli induce a more stable fusion pore, lea

268 content inside the vesicles decreases after repetitive stimuli, resulting in a higher average releas

269 ore, during, and after the presentation of a repetitive stimulus over 5 consecutive days.

270 , apical and basolateral flow, and flow plus repetitive stretch.

271 Repetitive stretching of tendon cells activates the AKT

272 We developed a mechanical model that mimics repetitive stretching of the amniotic membrane (AM) isol

273 ch to compare alternative splicing of large, repetitive structural genes in muscles.

274 s in chromosome segregation and disease, the repetitive structure and vast size of centromeres and th

275 the bioinformatic complexity associated with repetitive TEs in any organism.

276 x (dlPFC), in anxiety expression using 10 Hz repetitive TMS (rTMS).

277 Repetitive training induced Primed Neurons to shift from

278 key to this problem, as it provides data on repetitive trait evolution between lineages [4, 8].

279 We then temporarily inhibited PPC by repetitive transcranial magnetic stimulation (rTMS) and

280 m fMRI, diffusion tensor imaging, and online repetitive transcranial magnetic stimulation (rTMS) appl

281 work dynamics following low frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) as a

282 Despite growing evidence that repetitive transcranial magnetic stimulation (rTMS) can

283 dies have proposed therapeutic potential for repetitive transcranial magnetic stimulation (rTMS) in s

284 Repetitive transcranial magnetic stimulation (rTMS) is a

285 Critically, repetitive transcranial magnetic stimulation (rTMS) on p

286 efore, after, and 1 hour after low-frequency repetitive transcranial magnetic stimulation (rTMS) to t

287 ization, etc.,) or need for retreatment with repetitive transcranial magnetic stimulation (rTMS).

288 of three groups: piTBS monotherapy (n = 35), repetitive transcranial magnetic stimulation monotherapy

289 onded equally well to two different forms of repetitive transcranial magnetic stimulation therapy for

290 responsivity and related differentially to a repetitive transcranial magnetic stimulation treatment o

291 the standard protocol is an updated form of repetitive transcranial magnetic stimulation, and it is

292 degenerative disease that is associated with repetitive traumatic brain injury (TBI).

293 A qPCR test for the detection of the highly repetitive Tsol13 sequence has been developed and shown

294 Telomeres, the nucleoprotein structures with repetitive (TTAGGG) sequences at the end of chromosomes,

295 ication with ubiquitin (priming) followed by repetitive ubiquitin-to-ubiquitin attachment (elongation

296 Stereotypies-repetitive, unvarying, functionless behaviours -are comm

297 nmental education organizations should avoid repetitive use of the same site for their stream classes

298 ible for vegetative growth restriction after repetitive wounding.

299 Mbp), and from 3.6% to 0% within the highly repetitive X centromere (3.1 Mbp).

300 y reversible electrochemical reaction during repetitive Zn(2+) insertion and extraction, as demonstra