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1 nd proline-rich (30% of total) and contained repetitive regions.
2 h as copy number variations (CNVs) common to repetitive regions.
3 l portion of regulatory events that occur in repetitive regions.
4 bles analysis of genomic interactions across repetitive regions.
5 py-number neutral state and association with repetitive regions.
6 e genes in those references, particularly in repetitive regions.
7 ll struggle to accurately reconstruct highly repetitive regions.
8 ad sequencing is unable to interrogate these repetitive regions.
9 c laboratories, likely due to breakpoints in repetitive regions.
10 mplex rearrangements, and alterations within repetitive regions.
11 al difficulties in amplifying and sequencing repetitive regions.
12 d us to identify a function for one of these repetitive regions.
13 ently discriminate sequences with or without repetitive regions.
14 from the autosomes in their ploidy and large repetitive regions.
15 % for insertions and 13.75% for deletions in repetitive regions.
16 are able to extend paths into problematic or repetitive regions.
17  more between tissues than editing levels in repetitive regions.
18 variant detection by locating breakpoints in repetitive regions.
19 minimize the deleterious properties of these repetitive regions.
20 oblems caused by sequencing errors and short repetitive regions.
21 ces difficulties with regard to some complex repetitive regions.
22 stics of the protein-DNA interactions in non-repetitive regions.
23 an solve problems introduced by some complex repetitive regions.
24 es toward high GC content and intergenic and repetitive regions.
25 ently to annotate and prioritize variants in repetitive regions.
26 ger PacBio reads were better able to resolve repetitive regions.
27  is critical for accurately mapping reads to repetitive regions.
28 ed with a broad set of RNAs transcribed from repetitive regions.
29 elative positional homology for the internal repetitive regions.
30 e the alignment techniques are not ideal for repetitive regions.
31 cted to conserve Aliatypus spidroin internal repetitive regions.
32 ced sensitivity to detect SVs, especially in repetitive regions.
33 mily exhibit very little polymorphism in non-repetitive regions.
34      Accurate genome assembly is hampered by repetitive regions.
35  as 96% and unbiased coverage of GC-rich and repetitive regions.
36 a DNA sequence comprising repetitive and non-repetitive regions.
37 ntain 1046 putative protein-coding genes, 44 repetitive regions, 3 tRNAs, and 15 tRNAs.
38 ses, but especially for reads falling within repetitive regions, AlignerBoost dramatically increases
39 d the human species, the more complex 5' Yp2 repetitive region analyzed here appears to lack polymorp
40  were identified; rs13221869 is located in a repetitive region and was not a true variant in resequen
41 can more accurately map long reads to highly repetitive regions and align through insertions or delet
42 nance of cytosine methylation at CG sites in repetitive regions and central body regions of active ge
43 s needed to benchmark their newly accessible repetitive regions and complex variants.
44 oves read-mapping efficiency and coverage in repetitive regions and enhances haplotype phasing.
45 enging, in particular mapping short reads to repetitive regions and inferring expanded repeat lengths
46      Heterochromatic siRNAs are derived from repetitive regions and reinforce DNA methylation at targ
47 ddition, sequencing errors may produce false repetitive regions and uneven sequencing depth leads som
48 oietin 2 (Ang2, ANGPT2) promoter in a highly repetitive region, and SF-1-dependent activation was con
49 otein fibronectin (Fn) via an N-terminal non-repetitive region, and this protein-protein interaction
50 to identify structural events, cannot access repetitive regions, and fail to resolve the human genome
51 uence, end users working with sequences with repetitive regions are faced with 'ready-to-use' deposit
52 cient to map reads uniquely, especially when repetitive regions are long and nearly identical to each
53 rticular, non-coding regulatory elements and repetitive regions are often difficult to target with sp
54  be used to localize centromeres, telomeres, repetitive regions as well as unique regions, and total
55 arding sites with low mappability and highly repetitive regions, as well as sites with low genotype a
56 ation and host colonization; they comprise a repetitive region ("B region") and an N-terminal host co
57 s of high P-cloud density were identified as repetitive regions based on a sliding window approach.
58 some, which are known to contain GC-rich and repetitive regions, but at the distal tip of the largest
59                       RAmbler (1) identifies repetitive regions by detecting unusually high coverage
60 , we tackle the problem of assembling highly repetitive regions by developing a novel algorithm that
61                            The length of its repetitive region can be reduced while preserving its fu
62 methods struggle with this, primarily due to repetitive regions causing complex graph tangles, leadin
63          Sequence comparisons of the complex repetitive region close to the 5' end of this gene acros
64 des a large replication protein (RepA) and a repetitive region composed of a 35 bp iteron sequence re
65 anical phenotype arises from the B-domain; a repetitive region composed of alternating E and G5 subdo
66 glutamylates RPGR(ORF15) in its Glu-Gly-rich repetitive region containing motifs homologous to the al
67                         The assembly of such repetitive regions creates a need for their de novo anno
68 ssociated capsule transport genes flanked by repetitive Regions D and D'.
69 etic contribution to body mass have excluded repetitive regions due to the technical limitations of p
70 r large insertions (>=50 bp) and variants in repetitive regions, enabling the inclusion of these clas
71 bler specialized for the assembly of complex repetitive regions exclusively from Pacific Biosciences
72 ding regions was mainly achieved using novel repetitive region filters that were specifically designe
73              This region bears similarity to repetitive regions found in many transcription factors.
74 nome is unreliable in highly polymorphic and repetitive regions, further impacting genotyping perform
75        Transposable elements (TEs) and other repetitive regions have been shown to contain gene regul
76                                    While the repetitive region heavily influences silk fiber mechanic
77  Surprisingly, three different hypervariable repetitive regions in csd are present in the three speci
78  the assembly and variation analysis of such repetitive regions in Drosophila melanogaster, offering
79                                              Repetitive regions in eukaryotic genomes often contain i
80 r, scaffolding still faces the challenges of repetitive regions in genome, sequencing errors and unev
81            When extending one sequence seed, repetitive regions in the genome always cause multiple f
82 ion is a powerful technique to analyze large repetitive regions in the higher eukaryotic genomes and
83 aracterized 36 previously unidentified large repetitive regions in the proximity of sequence assembly
84 that the O-linked sites comprise independent repetitive regions in which each acceptor serine has a r
85 ifficult to study nucleotide polymorphism in repetitive regions, including certain types of structura
86 n of replication resources to origins within repetitive regions, induced by SIR2 deletion, leads to p
87 promote redistribution of H3K36me2 away from repetitive regions into active genes, which associate wi
88               Detecting sequences containing repetitive regions is a basic bioinformatics task with m
89 B2, and CEBPB) and global methylation, using repetitive region LINE-1 and ALUYb8 sequences.
90  to determine contiguous sequence for highly repetitive regions means that centromeres fall within mu
91 nsertions or deletions of 5 nucleotides in a repetitive region of avrBs2.
92         In contrast, deletion of the central repetitive region of LapA, consisting of 37 repeats of 1
93 te linear epitopes within the C terminus and repetitive region of LNA, detected antigen in primary ef
94 s included 23 families with mutations in the repetitive region of RPGR exon 15 that would have been m
95 one-half of the domains in the extracellular repetitive region of SasG are intrinsically unfolded in
96                       We have thus defined a repetitive region of the genomes of gammaherpesviruses a
97                                          The repetitive region of Xenopus TFIIS.h apparently correspo
98 ast centromere is complex, containing highly repetitive regions of DNA showing the characteristics of
99  Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes.
100                     Megabase-sized, complex, repetitive regions of genomes are poorly studied, due to
101      Segmental duplications and other highly repetitive regions of genomes contribute significantly t
102              However, interactions in highly repetitive regions of genomes have proven difficult to m
103 d hence underestimate biological signal from repetitive regions of genomes.
104                         The most dynamic and repetitive regions of great ape genomes have traditional
105 nomic alterations in previously inaccessible repetitive regions of HGSOC, including centromeric and t
106 ng the complexity of the highly recalcitrant repetitive regions of higher plant genomes.
107                                              Repetitive regions of reads are detected on the basis of
108 igate the chromatin states of the coding and repetitive regions of the allopolyploid wheat genome.
109 ng differences in the epigenome occurring at repetitive regions of the Arabidopsis genome.
110 romatin remodeler with roles in silencing of repetitive regions of the genome and in recruitment of t
111 ng because many variants have breakpoints in repetitive regions of the genome and thus are difficult
112 ral variants are found in complex and highly repetitive regions of the genome making their identifica
113             Accurate phasing and assembly in repetitive regions of the genome remain challenging, how
114 hromatic sequences; however, the most highly repetitive regions of the genome still could not be asse
115 ions and mapping protein-DNA interactions in repetitive regions of the genome that are difficult to s
116                                           In repetitive regions of the genome, it may be difficult to
117 chieve thorough phasing across homozygous or repetitive regions of the genome, long-read sequencing t
118 rence sequence of the single-copy and middle-repetitive regions of the genome, produced using cytogen
119 s long enough to span and resolve complex or repetitive regions of the genome.
120 ieves notable improvements in calling SVs in repetitive regions of the genome.
121 .99% unveiled the structural features of all repetitive regions of the genome.
122 quencing because they tend to integrate into repetitive regions of the genome.
123 s process a large fraction of 6mAs locate in repetitive regions of the genome.
124 pportioning short sequencing reads to highly repetitive regions of the genome.
125 ds or help assemblers resolve ambiguities in repetitive regions of the genome.
126 t can allocate multi-mapping reads in highly repetitive regions of the genomes with high accuracy.
127                  The ability to characterize repetitive regions of the human genome is limited by the
128 of varying reference structures (such as the repetitive regions of the human genome), alignments can
129 o accurately quantify the activity of highly repetitive regions of the human genome.
130 information about haplotypes and variants in repetitive regions of the human genome.
131 ve areas of HMW glutenins are located in the repetitive regions of the protein and could show that tw
132 or the existence of four NK-lysin genes in a repetitive region on cattle chromosome 11.
133 ification of structural variants, sequencing repetitive regions, phasing of distant nucleotide change
134 ircles from unique regions of the genome and repetitive regions: rDNA and telomeric Y' regions.
135 y S phase followed by most of the intergenic repetitive regions replicating during middle S phase.
136 ergenic regions, low CG density regions, and repetitive regions show room for improvement across all
137                                The predicted repetitive regions strongly overlap with known repeat el
138                  Complicating the matter are repetitive regions subject to programmed rearrangements,
139 etermined for many model organisms; however, repetitive regions such as centromeres, telomeres, and s
140  with known repeat elements as well as other repetitive regions such as gene families, pseudogenes, a
141 suggesting that centromeres and other highly repetitive regions such as telomeres are a significant y
142 g, as existing methods are often confined to repetitive regions, suffer from low resolution, or requi
143 ely, the weakening of replication origins in repetitive regions suppresses these gaps.
144                                          The repetitive regions surrounding the core element are foun
145  fibre type may be due to differences in the repetitive region (tandem Z-repeats) in the Z-band part
146                                            A repetitive region termed the 100-base-pair repeat region
147                            Specifically, one repetitive region that has been the focus in studies of
148 -terminal catalytic NDK domain followed by a repetitive region that includes three IQ motifs and a hi
149 ntains many polymorphic, low-complexity, and repetitive regions that are difficult to sequence and an
150 hesin (WI-1) in yeast stages, which contains repetitive regions that bind host-cell receptors.
151 ences; many of these variants lie in complex repetitive regions that cannot be aligned from short-rea
152 he diversity, distribution, and evolution of repetitive regions that have shaped the human genome.
153 centromere protein A localizes within highly repetitive regions that were unmappable with short seque
154 of read mapping tools deteriorates in highly repetitive regions, there is a need to develop accurate,
155 s sites are evolutionarily less conserved in repetitive regions, they share the overall sequence char
156 t mutated copies permits the sequence of the repetitive region to be inferred by consensus methods.
157  epigenomic landscape associated with genes, repetitive regions, transposons, transcription, differen
158 ng RPGR-ORF15 but shortened by 654 bp in the repetitive region was placed under the control of a chic
159 uth sets constrain recall within challenging repetitive regions, we observe a mean SNV F1 score >0.99
160 bles comparative assessment of DNA breaks at repetitive regions, we show that centromeric DNA breaks
161                                  Focusing on repetitive regions, we show that in contrast to pericent
162 previous studies, is that indels and SNPs in repetitive regions were not assessed due to the difficul
163    Moreover, because of improved coverage in repetitive regions where short sequencing reads fail to
164 hese methods are mostly applicable to highly repetitive regions, whereas imaging regions with low or
165 able to capture entire isoforms and overcome repetitive regions, whereas short reads still provide im
166 c silencing mechanism at heterochromatic and repetitive regions, whole genome methylome analysis reve
167 ning regions using a single sgRNA and of non-repetitive regions with as few as four unique sgRNAs.
168         Each locus consisted of three highly repetitive regions with four nonrepetitive intervening r
169 Delta reveals copy number changes flanked by repetitive regions with high R-loop-forming potential.
170 ly annealing DNA sequences characteristic of repetitive regions within a genome.
171 g reads, contigs or partial assemblies), and repetitive regions within a target genome.

 
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