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1 xic stress by inhibition of an essential DNA replication factor.
2 onfunctional and fails to interact with Cut5 replication factor.
3 a regulatory process targeting this key DNA replication factor.
4 y directly targeting expression of the Cdc45 replication factor.
5 k whether it also functions as a specialized replication factor.
6 hat converts the inhibitor into a beneficial replication factor.
7 e in levels and chromatin association of DNA replication factors.
8 bably involved in its interaction with other replication factors.
9 of BPDE on the chromatin association of DNA replication factors.
10 of the cytoskeleton, and, unexpectedly, DNA replication factors.
11 the promoters of other coordinately induced replication factors.
12 alphavirus-like superfamily, encodes two RNA replication factors.
13 poly(A) signal influence expression of viral replication factors.
14 ntrol by regulating the transcription of DNA replication factors.
15 vely repressing mitotic, DNA repair, and DNA replication factors.
16 NUCLEAR ANTIGEN, which encode essential DNA replication factors.
17 r foci that contain HPV genomes and cellular replication factors.
18 c], cyclin D1/3, chromatin licensing and DNA replication factor 1 [Cdt1]), concomitant with increased
19 ases A and B and chromatin licensing and DNA replication factor 1 may explain the reduction in cellul
20 lization of gammaH2AX foci with the telomere replication factor 1 protein in untreated melanoma cells
21 anslation or translation of BMV RNA1-encoded replication factor 1a, and was independent of p20, a cel
22 evels and interactions of brome mosaic virus replication factors 1a and 2a polymerase (2apol) shifted
23 embrane-associated compartments, require BMV replication factors 1a and 2a, and use negative-strand R
25 Brome mosaic virus (BMV) encodes two RNA replication factors: 1a has a C-terminal NTPase/helicase
28 binding protein-Interacting Factor 1 [RIF1], Replication Factor A 3 [RFA3], Cell Division Cycle 13 [C
29 dition of Rta to Z(S186A) and the mixture of replication factors activated viral replication and late
30 serves the activity of several essential DNA replication factors, active processes may contribute to
31 bserved decline in the expression of ten DNA replication factors after the midblastula transition (MB
34 n is synthetic lethal with inhibition of DNA replication factors, allowing additional models to be se
36 cetylated proteins to include a critical DNA replication factor and provide an additional level of co
37 pathways for induction of this essential DNA replication factor and suggest a mechanism for oncogenic
38 ochondrial DNA (mtDNA) biosynthesis requires replication factors and adequate nucleotide pools from t
39 tool that may facilitate the study of other replication factors and aid in the discovery of novel in
41 ion by screening an RNAi library against DNA replication factors and identified multiple shRNAs again
44 heckpoint Rad complexes and the PCNA and RFC replication factors and thus provide further support for
46 patients with mutations in mitochondrial DNA replication factors, and show that these have distinct d
48 omic RNA1 (gB1) and RNA2 (gB2), encoding the replication factors, are packaged into two separate viri
49 rotein 7 (MCM7), an E2F-induced cellular DNA replication factor, as a novel biomarker for cervical ca
50 ry subunits, mitochondrial transcription and replication factors, as well as certain heme biosyntheti
51 after pre-RC formation to promote loading of replication factors at origins, a previously unrecognize
52 d origin usage by evaluating the kinetics of replication factor binding in fission yeast and show tha
53 the EBV lytic cycle, is a transcription and replication factor, binding to Zta response elements (ZR
54 nscriptional regulator and mitochondrial DNA replication factor, both in P493-6 lymphocytes with high
55 CDKs are thought to activate one or more replication factors, but the identities of these protein
56 infection induces the accumulation of a host replication factor by activating transcription of its ge
61 ating cell nuclear antigen (PCNA) loading by replication factor C (RFC) acts as the initial sensor of
62 oliferating cell nuclear antigen (PCNA), and replication factor C (RFC) and a reconstituted Mlh1-Pms1
63 , proliferating cell nuclear antigen (PCNA), replication factor C (RFC) and DNA polymerase delta.
64 plication clamp PCNA is loaded around DNA by replication factor C (RFC) and functions in DNA replicat
66 en (PCNA), and show that PCNA, together with replication factor C (RFC) and replication protein A (RP
73 , and D subunits of Saccharomyces cerevisiae replication factor C (RFC) clamp loader, respectively, a
75 ell nuclear antigen (PCNA) sliding clamp and replication factor C (RFC) clamp-loading complex, using
76 ELG1 protein, which comprises an alternative replication factor C (RFC) complex and plays an importan
78 visiae, this process involves an alternative replication factor C (RFC) complex that contains the fou
79 s, sliding clamps are loaded onto DNA by the replication factor C (RFC) complex, which consists of fi
80 igated the communication between subunits in replication factor C (RFC) from Archaeoglobus fulgidus.
85 ing cell nuclear antigen loading onto DNA by replication factor C (RFC) is a key step in eukaryotic D
87 netic experiments reveal that ATP binding to replication factor C (RFC) is sufficient for loading the
88 Rad17 homologs have extensive homology with replication factor C (RFC) subunits (p36, p37, p38, p40,
89 tin by a complex of Rad17 and the four small replication factor C (RFC) subunits (Rad17-RFC) in respo
90 Pase, is the bacterial homolog of eukaryotic replication factor C (RFC) that loads the sliding clamp
91 24 interacts with the four small subunits of replication factor C (RFC) to form the RFC-Rad24 complex
92 ometry to contain Rfc2 and Rfc3, subunits of replication factor C (RFC), a five subunit protein that
95 and DNA binding by Saccharomyces cerevisiae replication factor C (RFC), and present the first kineti
96 l nuclear antigen (PCNA) and show that PCNA, replication factor C (RFC), and replication protein A (R
97 y the Saccharomyces cerevisiae clamp loader, replication factor C (RFC), and the DNA damage checkpoin
98 When loaded onto primed DNA templates by replication factor C (RFC), PCNA acts to tether the poly
99 tionation of these crude extracts identified replication factor C (RFC), proliferating cell nuclear a
100 several DNA replication proteins, including replication factor C (RFC), proliferating cell nuclear a
101 on, hLigI interacts with and is inhibited by replication factor C (RFC), the clamp loader complex tha
102 is study, we describe an association between replication factor C (RFC), the clamp loader, and DNA li
104 dogenous and transfected Brd4 interacts with replication factor C (RFC), the conserved five-subunit c
105 utation in RFC4, encoding a small subunit of replication factor C (RFC), was found to display allele-
107 proliferating cell nuclear antigen (PCNA) in replication factor C (RFC)-catalyzed loading of the clam
108 e-molecule analysis, we demonstrate that the replication factor C (RFC)-CTF18 clamp loader (RFC(CTF18
109 hat Ctf18, Ctf8, and Dcc1, the subunits of a Replication Factor C (RFC)-like complex, are essential f
116 DNA requires the activity of a clamp-loader [replication factor C (RFC)] complex and the energy deriv
117 a nucleotide-bound eukaryotic clamp loader [replication factor C (RFC)] revealed a different and mor
119 ating cell nuclear antigen (PCNA, clamp) and replication factor C (RFC, clamp loader), we have examin
121 ding proteins have been reported previously: replication factor C (the PCNA clamp loader), family B D
122 Our results demonstrate that S. cerevisiae Replication Factor C (yRFC) can load yPCNA onto 5'-ssDNA
123 CTF7/ECO1, POL30 (PCNA), and CHL12/CTF18 (a replication factor C [RFC] homolog) genetically interact
124 pha, proliferating cell nuclear antigen, and replication factor C activate MutLalpha endonuclease to
126 h three- and four-subunit complexes required replication factor C and proliferating cell nuclear anti
127 rms a replication complex in the presence of replication factor C and proliferating cell nuclear anti
129 n A, proliferating cell nuclear antigen, and replication factor C and was active in the SV40 DNA repl
134 tion in the large subunit of the replicative replication factor C complex (rfc1-1) increased the expa
135 ase delta/proliferating cell nuclear antigen/replication factor C complex on telomeric templates that
136 pendent phosphorylation; associates with the replication factor C complex, a critical component of th
137 ion: proliferating cell nuclear antigen, the replication factor C complex, DNA polymerase delta, flap
140 ng cell nuclear antigen and the clamp loader replication factor C facilitated DNA synthesis with Dpo3
141 ticipation that the discovery of this unique replication factor C homolog will lead to critical insig
142 a its non-conserved C-terminal domain (CTD); replication factor C interaction results in approximatel
145 s two similar small subunits (M. acetivorans replication factor C small subunit (MacRFCS)) and one la
146 lelic intronic AAGGG repeat expansion in the replication factor C subunit 1 (RFC1) gene as the cause
150 gammaS), a nonhydrolyzable analog of ATP, to replication factor C with a N-terminal truncation (Delta
152 ation factors, and the clamp loader complex (replication factor C) remained tethered to chromatin.
154 ntenance (MCM) 3' --> 5' DNA helicase, PolB, replication factor C, and proliferating cell nuclear ant
155 sence of proliferating cell nuclear antigen, replication factor C, and single-stranded binding protei
157 These functions include loading onto DNA by replication factor C, as well as Okazaki fragment synthe
159 liferating cell nuclear antigen clamp loader replication factor C, DNA polymerase delta, and DNA liga
160 conformations matching the helical pitch of Replication Factor C, it is not biased toward a right-ha
161 ix purified human proteins: AP endonuclease, replication factor C, PCNA, flap endonuclease 1 (FEN1),
162 system comprised of MutS alpha, MutL alpha, replication factor C, proliferating cell nuclear antigen
163 S. pombe Uve1p, Rad2p, DNA polymerase delta, replication factor C, proliferating cell nuclear antigen
164 ating cell nuclear antigen (PCNA) loading by replication factor C, providing a potential mechanism fo
166 loaded onto the template-primer junction by replication factor C, the C-terminal domain of PCNA medi
167 this process through a pathway that includes replication factor C, the chromatin assembly factor Asf1
168 a circular substrate without the addition of replication factor C, which is the protein responsible f
169 nterfaces by the ATP-dependent clamp loader, Replication Factor C, whose clamp-interacting sites form
170 loaded onto DNA by a dedicated complex, the replication factor C, whose mechanism has been studied i
171 d circular DNA do in fact support MutSbeta-, replication factor C-, and PCNA-dependent activation of
172 log 6, Exonuclease 1, replication protein A, replication factor C-Delta1N, proliferating cell nuclear
174 factor is loaded onto DNA by the Rad24-RFC (replication factor C-like complex with Rad24) clamp load
175 es now present data strongly implicating the replication factor C-like complex, Elg1/ATAD5-RLC, in th
181 th the 9-1-1 heterotrimer reminiscent of the replication factor C/proliferating cell nuclear antigen
183 re of the five-protein clamp loader complex (replication factor-C, RFC) of the yeast Saccharomyces ce
185 on factors: replication protein A70 (RPA70), replication factor C1 (RFC1), and DNA polymerase delta.
187 BRCA1/2), Poly-ADP ribose polymerase (PARP), replication factor c2-5 (Rfc2-5), ataxia telangiectasia
188 The top hits based on the combined data-replication factor C3 (RFC3), FAM111A, and interferon re
192 Here we show that stabilization of the DNA replication factor Cdt1, a substrate of cullins 1 and 4,
193 -G2-M phases produces high levels of the DNA replication factor Cdt1, and this leads to efficient Mcm
197 nt form of the nuclear matrix-associated DNA replication factor Ciz1 is present in 34/35 lung tumors
199 biallelic intronic AAGGG repeat expansion in replication factor complex subunit 1 (RFC1) as the cause
200 ors, proliferating cell nuclear antigen, and replication factor complex, was disrupted by DeltaNLA.
203 ver one such metazoa-specific process: a new replication factor, cyclin-dependent kinase 8/19-cyclinC
205 of interactions between the Escherichia coli replication factor DnaC protein and the DnaB helicase ha
206 e report that MAT switching requires the DNA replication factor Dpb11, although it does not require t
207 dDP eliminates G(1)-S transcription of known replication factors during embryogenesis and compromises
208 nding model to decipher the roles of various replication factors during metazoan DNA replication.
212 s bound by a virus-encoded transcription and replication factor E2, which binds to a 12 bp recognitio
216 ed by competition among origins for limiting replication factors establishes the timing and efficienc
217 These findings make CDC45 the only putative replication factor experimentally proven to be essential
218 been well established, its effects on viral replication factor expression and plasmid replication of
219 re we investigate the role of one of the DNA replication factors, flap endonuclease I (FEN1), in regu
222 Rbf1-dependent repression of E2f1-regulated replication factor genes, which are expressed continuous
223 Saccharomyces cerevisiae, but not other DNA replication factors, greatly reduced PFA at replication
225 e through S phase and implicated several DNA replication factors in silencing, later works showed tha
226 ion defect is due to dosage insufficiency of replication factors in the nucleus, which stems from two
227 te in vitro plasmid DNA replication, whereas replication factors in the polymerase fractions are stri
228 Vpr indirectly binds MCM10, a eukaryotic DNA replication factor, in a Vpr-binding protein (VprBP) (Vp
229 o a regulator of viral gene expression and a replication factor, in association with the viral E1 pro
230 ve restart was inhibited along with numerous replication factors, including MCM6 and RPA, the latter
231 mutations and the genes encoding several DNA replication factors, including POL1, CTF4, DNA2, and CHL
234 identity and order of assembly of eukaryotic replication factors is highly conserved across all speci
235 This motif, named RRF (for repression of replication factors), is conserved in the promoters of o
236 tes polymerase translation relative to other replication factors, just as many single-component RNA v
237 irects cell-specific expression of the viral replication factor large T antigen, and thus transcripti
239 for optimal replication, encode a conserved replication factor, LEF-7, that manipulates the DDR via
243 that the G1 phase-specific expression of the replication factor Mcm2 is a useful marker for detecting
245 s revealed significantly lower levels of the replication factors Mcm4, Mcm7, and Cdc45 at replication
246 icing factors Rbmx, Sfrs5 and Sfrs7, the DNA replication factors Mcm5 and Brd4, phosphoinositide-3-ki
247 sion, and prevented chromatin recruitment of replication factor Mcm7, demonstrating that JADE1 is req
248 nt cells also retain high levels of tethered replication factors, MCM7 and PCNA, indicating that DNA
249 tions of the DnaB-primase complex with other replication factors might be critical for determining th
251 proteins, transcription regulation proteins, replication factors, modifying enzymes, and a number of
252 racts with DNA as both a transcription and a replication factor, modulates both intracellular signal
253 lisome) by yet unidentified host factors [Mu replication factors (MRF alpha 2)], which displace the t
256 in determining the function of the different replication factors once they have been assembled at the
257 ested that the direct interaction of RB with replication factors or sites of DNA synthesis may contri
259 Our data indicate that Cdc2 phosphorylates replication factor Orp2, a subunit of the origin recogni
261 eckpoint components with limited homology to replication factors PCNA and RF-C, respectively, suggest
262 l, Dzantiev et al. present evidence that the replication factors PCNA and RFC modulate the directiona
266 n S phase and replicates via accumulation of replication factors, rather than recruitment of DNA to p
267 h HPV16 E1, E2, and a number of the cellular replication factors: replication protein A70 (RPA70), re
268 been shown to be structurally similar to the replication factors, RFC clamp loader and proliferating
269 re11/NBS1 complex and Rad51/Rad52 along with replication factors (RPA) and telomere binding proteins
271 xRTS, which bears homology to the yeast replication factors Sld2/DRC1, is essential for DNA repl
274 ays a direct role in recruiting cellular DNA replication factors, such as replication protein A or po
276 Moreover, the viral E2 transcription and replication factor that is expressed at high levels in d
277 the yeast Sld3 protein, is an essential DNA replication factor that is regulated by cyclin-dependent
280 drug targets because they are essential DNA replication factors that are highly expressed in cancer
281 some maintenance) proteins are essential DNA replication factors that each contain a putative ATP bin
282 ycle progression, here we identify three DNA replication factors that interact with each other and th
283 herichia coli DnaB helicase complex with the replication factor, the DnaC protein, have been examined
284 RB, we observed the attenuation of multiple replication factors, the complete cessation of DNA synth
285 rongly attenuated the RNA levels of multiple replication factors, their protein expression was not di
287 cm10) is an essential eukaryotic DNA-binding replication factor thought to serve as a scaffold to coo
292 wn to recruit many of the necessary cellular replication factors to the viral origin of replication.
293 show that the binding of cellular and viral replication factors to viral RNA is conserved despite ge
294 In particular, expression of the viral DNA replication factor UL84 is affected by the deletion of I
295 alization of the human cytomegalovirus viral replication factor UL84 relative to other proteins invol
297 y, several proteins, including the viral DNA replication factors UL84 and UL57, were identified by ma
299 stein-Barr virus (EBV) encodes a set of core replication factors used during lytic infection in human