ライフサイエンスコーパス: replication protein A

1 the single-stranded DNA binding protein RPA (replication protein A).

2 f HEL308 is specifically stimulated by human replication protein A.

3 ctive capacity of the ssDNA-binding protein, replication protein A.

4 atalytic, requires ATP, and is stimulated by replication protein A.

5 e the physical interaction of Mei5-Sae3 with replication protein A.

6 d by the single-stranded DNA-binding protein replication protein A.

7 This inhibition can be overcome by replication protein A.

8 tranded DNA bubbles that are stably bound by replication protein A.

9 structure containing multifunctional FHV RNA replication protein A.

10 trimeric single-stranded DNA binding protein replication protein A.

11 because it does not require interaction with replication protein A.

12 plex that contains multifunctional viral RNA replication protein A.

13 ning topoisomerase III alpha, RMI1, RMI2 and replication protein A.

14 Furthermore, we show that replication protein A 2 and retinoblastoma protein are b

15 acting protein (ATRIP) and the ATR substrate replication protein A 32 (RPA32).

16 rate of DNA break formation, as measured by replication protein A accumulation at the site of damage

17 racts physically with two cellular proteins, replication protein A and DNA polymerase alpha-primase (

18 t proteins, we show here in studies of human replication protein A and Escherichia coli single-strand

19 nomic RNAs; RNA1 encodes multifunctional RNA replication protein A and RNA interference suppressor pr

20 SIRT6 depletion impaired the accumulation of replication protein A and single-stranded DNA at DNA dam

21 sphorylation of AID, which led to binding of replication protein A and subsequent propagation of the

22 completely lacked sequences similar to RPA (replication protein A) and DNA Helicases reported in oth

23 actor C, proliferating cell nuclear antigen, replication protein A, and DNA polymerase delta that sup

24 sociates with Cdc45, DNA polymerase epsilon, replication protein A, and two replication factor C comp

25 signaling and nucleotide excision repair is replication protein A, and we find that its accumulation

26 exhibited good specificity for XPA over RPA (replication protein A), another DNA-binding protein that

27 ent of DNA repair proteins BRIT1, BRCA1, and replication protein A at early steps of HR repair.

28 g because late G2 cells fail to recruit RPA (replication protein A), ATR (ataxia telangiectasia and R

29 to TIN2/TRF1/TRF2, POT1a is thought to block replication protein A binding to the single-stranded tel

30 ith single-stranded DNA-binding protein RPA (replication protein A) causes binding of Rad24-RFC via i

31 ctable Mcm2 phosphorylation in vivo, reduced replication protein A-ChIP signal at an origin, and dimi

32 We also observed a substantially reduced replication protein A- chromatin immunoprecipitation sig

33 However, chromatin enrichment of replication protein A, Claspin, Rad17-RFC, and Rad9-Rad1

34 ion by nucleating the Rad51 recombinase onto replication protein A-coated single-stranded DNA strands

35 ation mediator in enabling hRad51 to utilize replication protein A-coated ssDNA as recombination subs

36 , the oxidative deamination product of C, in replication protein A-coated ssDNA template and inhibits

37 ng Rad51 nucleoprotein filament formation on replication protein A-coated ssDNA.

38 e have recently characterized an alternative replication protein A complex (aRPA) that is unique to p

39 The replication protein A complex (RPA) plays a crucial role

40 ion complexes (PICs) identified Sub1 and the replication protein A complex (RPA), both of which bind

41 imilarities to corresponding subunits in the replication protein A complex, further supporting an evo

42 ough a non-R-loop mechanism involving an AID-replication protein A complex.

43 protein similar to the second subunit of the replication protein A conserved from yeast to mammals.

44 rsal signal consisting of genomic regions of replication protein A-covered single-stranded DNA.

45 g agents and display hyperphosphorylation of Replication Protein A due to increased activity of DNA2

46 tion sensitive genes, repaire related genes, replication protein A encoding gene, DNA replication ini

47 ts in RPA2, a homolog of yeast and mammalian replication protein A, exhibit loss of silencing at tran

48 Furthermore, IR-induced replication protein A foci formation is defective in ATM

49 damage as evidenced by increased gamma-H2AX, replication protein A foci, and Chk1 kinase phosphorylat

50 in cells following DNA damage, while leaving replication protein A focus formation unaffected.

51 r, the single-stranded binding protein human replication protein A (hRPA) restricts sliding and enfor

52 Human replication protein A (hRPA), a heterotrimeric single-st

53 p53 (p53TAD) and the 70 kDa subunit of human replication protein A (hRPA70) was investigated using he

54 ion by hMSH2-hMSH6 is not abrogated by human replication protein A (HsRPA) bound to the displaced sin

55 interactions between human RecQ proteins and Replication Protein A, identify SSB as a broadly conserv

56 he formation of intranuclear foci by ATR and replication protein A, implicating a functional role for

57 in conjunction with flap endonuclease 1 and replication protein A in DNA lagging strand replication

58 orthologs of the two OB fold/one zinc finger replication protein A in Methanosarcina acetivorans and

59 n in CD4+ lymphocytes is the accumulation of replication protein A in nuclear foci, an indication tha

60 MutSalpha or MutLalpha with Rad17, Rad9, or replication protein A in the extract system.

61 on ataxia telangiectasia mutated, NBS1, and replication protein A, indicating it functions after DNA

62 Replication protein A is known to stimulate the 5'- to 3

63 ed DUE-B inhibited chromatin replication and replication protein A loading in the presence of endogen

64 tion, the multifunctional, transmembrane RNA replication protein A of the nodavirus flock house virus

65 bound by the single-stranded binding protein Replication Protein A or are targeted by cellular nuclea

66 inds duplex regions up to 500 bp; and either replication protein A or Escherichia coli single strande

67 d in HR-defective cells do not colocalize to replication protein A or gammaH2AX, excluding the possib

68 ng cellular DNA replication factors, such as replication protein A or polymerase alpha-primase, to re

69 duced phosphorylation of Chk1 and UV-induced replication protein A phosphorylation and chromatin bind

70 FANCJ promotes replication protein A phosphorylation and the arrest of

71 e TIM-Tipin complex to the 34 kDa subunit of replication protein A provides a biochemical explanation

72 tment and activation appeared independent of replication protein A, Rad17, and the Rad9-Hus1-Rad1 pro

73 igen (PCNA) by regulating the recruitment of replication protein A, Rad18, and helicase-like transcri

74 olog 2 (Msh2)-MutS homolog 6, Exonuclease 1, replication protein A, replication factor C-Delta1N, pro

75 Salpha, MutLalpha, exonuclease 1 (Exo1), and replication protein A (RPA) (in the absence or presence

76 to be single-stranded DNA (ssDNA), coated by replication protein A (RPA) and containing a primer-temp

77 Human replication protein A (RPA) and HCV NS5A recruit NS5BDel

78 strate that SMARCAL1 directly interacts with Replication protein A (RPA) and is recruited to sites of

79 binds directly to the ssDNA-binding protein Replication protein A (RPA) and is recruited to sites of

80 eplication stress-induced DNA damage markers replication protein A (RPA) and Ku.

81 gle-stranded DNA, which are rapidly bound by replication protein A (RPA) and other single-stranded DN

82 studies indicate that WRN is associated with replication protein A (RPA) and p53 in vivo before and a

83 ingle-stranded DNA (ssDNA)-binding proteins, replication protein A (RPA) and protection of telomeres

84 ecruit RNF4 resulted in defective loading of replication protein A (RPA) and Rad51 onto ssDNA.

85 Tipin interacted with replication protein A (RPA) and RPA-coated DNA, and RPA

86 The single strand binding proteins replication protein A (RPA) and telomere-specific POT1 s

87 single-stranded DNA (ssDNA)-binding complex replication protein A (RPA) and the checkpoint kinase CH

88 SB resection, and thereby for recruitment of replication protein A (RPA) and the protein kinase ATR t

89 ATRIP and replication protein A (RPA) are recruited to the earlies

90 entified single-stranded DNA binding protein replication protein A (RPA) as a regulator of the deposi

91 nover of the DSB-responsive factors MDC1 and replication protein A (RPA) at DNA damage sites and that

92 Human replication protein A (RPA) becomes phosphorylated on th

93 Replication protein A (RPA) bound to single-stranded DNA

94 he yeast single-stranded DNA binding protein replication protein A (RPA) but not by a mutant form of

95 Phosphorylation of replication protein A (RPA) by Cdk2 and the checkpoint k

96 uclease inhibition impairs radiation-induced replication protein A (RPA) chromatin binding, suggestin

97 n leads to the subsequent recruitment of the replication protein A (RPA) complex to facilitate retrot

98 proteins, we show that Sgs1, Top3, Rmi1, and replication protein A (RPA) coordinate catenation and de

99 Replication protein A (RPA) coordinates important DNA me

100 The replication protein A (RPA) DNA-binding protein has a pi

101 ing of complementary strands of DNA bound by replication protein A (RPA) during discrete repair pathw

102 hows that mutants first accumulate extensive replication protein A (RPA) foci, followed by increased

103 showed that HCV NS5A(S25-C447) and cellular replication protein A (RPA) functionally cooperate as a

104 Eukaryotic DNA-binding protein replication protein A (RPA) has a strand melting propert

105 vation-induced cytidine deaminase (AID) with replication protein A (RPA) has been proposed to promote

106 (PKA) and subsequent interaction of AID with replication protein A (RPA) have been proposed to play i

107 cribe a CCCH type of zinc finger domain in a replication protein A (RPA) homolog found in members of

108 A lesions, the ssDNA-binding protein complex replication protein A (RPA) in budding yeast (Saccharomy

109 The activity of human replication protein A (RPA) in DNA replication and repai

110 CST resembles Replication Protein A (RPA) in that the two complexes ha

111 demonstrate that MRN directly interacts with replication protein A (RPA) in unperturbed cells and tha

112 However, flaps escaping cleavage bind replication protein A (RPA) inhibiting FEN1.

113 on with Mcm2-7 during S phase, and decreased replication protein A (RPA) interaction with origin DNA

114 complished through modulation of the p53 and replication protein A (RPA) interaction.

115 Replication protein A (RPA) interacts with multiple chec

116 The single-stranded DNA-binding protein replication protein A (RPA) interacts with several human

117 Replication protein A (RPA) is a eukaryotic single-stran

118 Replication protein A (RPA) is a eukaryotic single-stran

119 Replication protein A (RPA) is a heterotrimeric (70, 32

120 Replication protein A (RPA) is a heterotrimeric protein

121 Replication protein A (RPA) is a heterotrimeric protein

122 Replication protein A (RPA) is a heterotrimeric protein

123 Replication protein A (RPA) is a heterotrimeric protein

124 Replication Protein A (RPA) is a heterotrimeric protein

125 Replication protein A (RPA) is a heterotrimeric, multido

126 Replication protein A (RPA) is a heterotrimeric, single-

127 Replication protein A (RPA) is a highly conserved hetero

128 ly known as the DNA damage response, wherein replication protein A (RPA) is a key regulator playing m

129 Replication protein A (RPA) is a single-stranded DNA-bin

130 Replication Protein A (RPA) is a single-stranded DNA-bin

131 The replication protein A (RPA) is a single-stranded DNA-bin

132 Replication protein A (RPA) is a ubiquitous eukaryotic s

133 Replication protein A (RPA) is an essential eukaryotic s

134 Replication protein A (RPA) is an essential heterotrimer

135 have shown that the balance between RADX and Replication Protein A (RPA) is critical for DNA replicat

136 Replication protein A (RPA) is displaced from single-str

137 Replication protein A (RPA) is involved in many aspects

138 The replication protein A (RPA) is involved in most, if not

139 Replication protein A (RPA) is involved in multiple stag

140 ed whether the interaction of p53 with human replication protein A (RPA) is necessary for the regulat

141 Replication protein A (RPA) is the main eukaryotic ssDNA

142 Replication protein A (RPA) is the major single-stranded

143 Replication protein A (RPA) is the major single-stranded

144 Replication protein A (RPA) is the predominant eukaryoti

145 Replication protein A (RPA) is the primary eukaryotic si

146 Replication protein A (RPA) is the ubiquitous, eukaryoti

147 ent and alignment of DNA processing factors, replication protein A (RPA) lies at the heart of dynamic

148 n of the single-stranded DNA binding protein replication protein A (RPA) on damaged chromatin and sev

149 SV40 T antigen (Tag) helicase actively loads replication protein A (RPA) on emerging single-stranded

150 ow that Sgs1 acts upon ssDNA bound by either replication protein A (RPA) or the recombinase Rad51.

151 Replication protein A (RPA) plays essential roles in DNA

152 t signaling but correlates with the level of replication protein A (RPA) recruited to chromatin.

153 n of the single-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERC

154 using purified truncated Rad52 proteins and replication protein A (RPA) showed that annealing of oli

155 ion of the single-strand DNA-binding protein replication protein A (RPA) stimulated the helicase reac

156 Replication protein A (RPA) stimulates DNA end resection

157 e conserved eukaryotic ssDNA-binding protein replication protein A (RPA) suggest a novel mechanism by

158 with the single-stranded DNA-binding protein replication protein A (RPA) to displace BamHI-E111A boun

159 specifically required for the recruitment of replication protein A (RPA) to ICL-stalled replication f

160 ' overhangs and facilitating the switch from replication protein A (RPA) to protection of telomeres 1

161 ught to facilitate the handoff of ssDNA from replication protein A (RPA) to the RAD51 recombinase dur

162 Mammalian replication protein A (RPA) undergoes DNA damage-depende

163 reveals an increase in chromatin binding of replication protein A (RPA) upon Vpr expression.

164 TERRA and leads to persistent association of replication protein A (RPA) with telomeres after DNA rep

165 the expression of Bid and the association of replication protein A (RPA) with the ATR- interacting pr

166 Human replication protein A (RPA), a heterotrimer composed of

167 Very little is known about protozoan replication protein A (RPA), a heterotrimeric complex cr

168 Replication protein A (RPA), a major eukaryotic ssDNA-bi

169 e), a novel protein interaction inhibitor of replication protein A (RPA), a protein involved in the A

170 ses that include the hyperphosphorylation of replication protein A (RPA), a protein that plays key ro

171 Replication protein A (RPA), a single-stranded DNA (ssDN

172 study, we have examined the ability of human replication protein A (RPA), a single-stranded DNA bindi

173 We report here that RFWD3 associates with replication protein A (RPA), a single-stranded DNA-bindi

174 ated the potential interaction of FANCJ with replication protein A (RPA), a single-stranded DNA-bindi

175 orylated on serine residue 38 interacts with replication protein A (RPA), a ssDNA binding protein, to

176 In biochemical assays, replication protein A (RPA), a ssDNA-binding protein, as

177 In contrast, genomic occupancy of replication protein A (RPA), an AID cofactor, was restri

178 The ssDNA-binding replication protein A (RPA), an essential complex involv

179 Here we show that replication protein A (RPA), an essential replisome comp

180 Here we show that replication protein A (RPA), an ssDNA-binding protein, i

181 RNA polymerase II, replication protein A (RPA), and components of the ATR s

182 ion, including DNA polymerase alpha-primase, replication protein A (RPA), and more recently, human to

183 ent of long flaps, coating of those flaps by replication protein A (RPA), and sequential cleavage of

184 the archaeal/eukaryotic functional homolog, replication protein A (RPA), are essential for most aspe

185 Thus, the archaeal protein is called replication protein A (RPA), as in eukaryotes.

186 nd interacts with the essential NER protein, replication protein A (RPA), at these lesions.

187 of the DNA damage sensor complex, including replication protein A (RPA), ataxia telangiectasia and R

188 In the presence of replication protein A (RPA), but not Escherichia coli si

189 the uracils created by A3A- colocalize with replication protein A (RPA), but not with A3A.

190 Human replication protein A (RPA), composed of RPA70, RPA32, a

191 coded T antigen and three cellular proteins, replication protein A (RPA), DNA polymerase alpha/primas

192 Replication protein A (RPA), essential for DNA replicati

193 The single-stranded DNA-binding protein, replication protein A (RPA), governs cleavage activity.

194 nless it is destabilized by proteins such as replication protein A (RPA), GQ could interfere with DNA

195 er components of the repair complex, such as replication protein A (RPA), is controlled in part by a

196 e single strand DNA (ssDNA)-binding protein, replication protein A (RPA), is essential for DNA replic

197 aryotic single-stranded DNA-binding protein, replication protein A (RPA), is essential in DNA metabol

198 ger overhanging DNA is largely eliminated by replication protein A (RPA), likely because of the previ

199 In the presence of replication protein A (RPA), MRN acts as a processivity

200 uman activities: MutSalpha, MutLalpha, EXOI, replication protein A (RPA), proliferating cell nuclear

201 revealed that chromosome-associated foci of replication protein A (RPA), RAD51 and DMC1 are less abu

202 Increased replication protein A (RPA), Rad9, and ataxia telangiect

203 2-Msh6 (or Msh2-Msh3), exonuclease 1 (Exo1), replication protein A (RPA), RFC, PCNA, and DNA polymera

204 ligase that interacts with and ubiquitylates replication protein A (RPA), show profound defects in IC

205 Replication protein A (RPA), the eukaryotic single-stran

206 Replication protein A (RPA), the eukaryotic single-stran

207 Replication protein A (RPA), the eukaryotic ssDNA-bindin

208 case, identified a physical interaction with replication protein A (RPA), the major cellular single-s

209 Replication protein A (RPA), the major eukaryotic single

210 Replication protein A (RPA), the major eukaryotic single

211 Replication protein A (RPA), the major eukaryotic single

212 Recent studies revealed that replication protein A (RPA), the major ssDNA-binding pro

213 Replication protein A (RPA), the major ssDNA-binding pro

214 to replication forks via an interaction with replication protein A (RPA), the major ssDNA-binding pro

215 of the SOSS1 complex, containing SSB1, with Replication Protein A (RPA), the primary single-strand D

216 Human replication protein A (RPA), the primary single-stranded

217 polymerase delta (pol delta) is assisted by replication protein A (RPA), the single-stranded DNA-bin

218 Using the eukaryotic ssDNA binding protein, Replication Protein A (RPA), we demonstrate that NMR spe

219 he previously characterized interaction with replication protein A (RPA), we found that SMARCAL1 form

220 roliferating Cell Nuclear Antigen (PCNA) and Replication Protein A (RPA), which are critical for DNA

221 Rad3(ATR/Mec1) associates with replication protein A (RPA), which binds single-stranded

222 Long flaps are bound by replication protein A (RPA), which inhibits FEN1.

223 accumulation of single-stranded DNA bound by replication protein A (RPA), which triggers activation o

224 osphorylation of the Ser-15 site of p53 in a replication protein A (RPA)- and ATM and Rad3-related (A

225 In this study we identified RFWD3 as a novel replication protein A (RPA)-associated protein.

226 Analysis of replication protein A (RPA)-associated proteins reveals

227 SMARCAL1 contains a Replication protein A (RPA)-binding motif similar to tha

228 AH2 catalyzes the ATP-dependent rewinding of replication protein A (RPA)-bound complementary single-s

229 Replication protein A (RPA)-bound flaps inhibit cleavage

230 tivated primarily through the persistence of replication protein A (RPA)-bound single-stranded DNA at

231 or APEX2), is required for the generation of replication protein A (RPA)-bound single-stranded DNA, t

232 es the formation of dsDNA from complementary Replication protein A (RPA)-bound ssDNA.

233 e protein F (CENP-F), allowing ATR to engage replication protein A (RPA)-coated centromeric R loops.

234 Results show that displaced, replication protein A (RPA)-coated flaps could readily b

235 processive with PCNA, over at least 5 kb, on Replication Protein A (RPA)-coated primed single strand

236 n addition, formation of irradiation-induced replication protein A (RPA)-coated single-stranded DNA (

237 regulatory partner of ATR, binds directly to replication protein A (RPA)-coated ssDNA and enables the

238 the binding interactions of human RAD52 with replication protein A (RPA)-coated ssDNA, and we monitor

239 at DNA damage sites and is not recruited by replication protein A (RPA)-coated ssDNA.

240 (MRE11)-dependent accumulation of (phospho-)replication protein A (RPA)-coated ssDNA.

241 ogression accompanied by increased levels of replication protein A (RPA)-containing foci.

242 g partner ATR-interacting protein (ATRIP) to replication protein A (RPA)-covered single-stranded DNA

243 D3-related (ATR) signals the accumulation of replication protein A (RPA)-covered single-stranded DNA

244 The replication protein A (RPA)-ssDNA complex formed at arre

245 single-stranded DNA (ssDNA) that is bound by replication protein A (RPA).

246 , the nuclease/helicase Dna2, Top3-Rmi1, and replication protein A (RPA).

247 with a single-stranded DNA binding protein, replication protein A (RPA).

248 comprising MRE11, RAD50, and NBS1 (MRN); and Replication protein A (RPA).

249 eraction of Tipin with the 34-kDa subunit of replication protein A (RPA).

250 he human single-stranded DNA-binding protein replication protein A (RPA).

251 ence by the single-strand DNA-binding factor replication protein A (RPA).

252 oordinator of all DNA metabolic processes is Replication Protein A (RPA).

253 cation forks via its direct interaction with Replication protein A (RPA).

254 the eukaryotic ssDNA-binding protein complex replication protein A (RPA).

255 ed for flaps that become long enough to bind replication protein A (RPA).

256 1p appears to depend on its interaction with replication protein A (RPA).

257 ucts and that this activity is stimulated by replication protein A (RPA).

258 ility to anneal ssDNA that is complexed with replication protein A (RPA).

259 eplication that is suppressed by mutation of replication protein A (RPA).

260 rity to domains in the ssDNA-binding protein replication protein A (RPA).

261 with single-stranded DNA (ssDNA) coated with replication protein A (RPA).

262 ral single-stranded DNA binding heterotrimer replication protein A (RPA).

263 the MRN (Mre11, Rad50, and Nbs1) complex and replication protein A (RPA).

264 RFA1 and RFA2, genes that encode subunits of replication protein A (RPA).

265 ssDNA) overhangs, which are quickly bound by replication protein A (RPA).

266 ted to form single-stranded DNA, which binds replication protein A (RPA).

267 Rad51 on single-stranded DNA pre-occupied by replication protein A (RPA).

268 g protein Teb1, paralogous to heterotrimeric replication protein A (RPA).

269 rming 3'-ssDNA tails that become coated with replication protein A (RPA).

270 could be suppressed by exogenously expressed replication protein A (RPA).

271 ch can be recognized as a DNA damage site by replication protein A (RPA).

272 g DNA bubble-like structure that is bound by replication protein A (RPA).

273 trimeric single-stranded DNA binding protein replication protein A (RPA).

274 m, with BRCA1 IRIF forming between 53BP1 and replication protein A (RPA).

275 -stranded DNA (ssDNA) that is complexed with replication protein A (RPA); the resulting nucleoprotein

276 lutionarily related to the 32-kDa subunit of replication protein A (RPA-32) and contains an oligonucl

277 on single-stranded DNA (ssDNA) protected by replication protein-A (RPA) and annealing of RPA-coated

278 ble-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing R

279 Rad51, Rad52, and replication protein-A (RPA) play crucial roles in the re

280 helicase Sgs1 and the ssDNA-binding protein replication protein-A (RPA).

281 ged DNA, promotes DNA end joining, regulates replication protein A (RPA2) phosphorylation and ubiquit

282 rminal domain of the intermediate subunit of replication protein A (RPA32C) was identified and charac

283 e N-terminal domain of the 70 kDa subunit of replication protein A (RPA70N).

284 g properties of the Saccharomyces cerevisiae replication protein A (scRPA) using fluorescence titrati

285 Replication protein A stimulated FANCJ G4 unwinding, whe

286 Our results also indicate that the yeast replication protein A stimulated the ATPase activity of

287 ctors and identified multiple shRNAs against Replication Protein A, subunit 3 (RPA3).

288 The nuclear replication protein A subunits (RPA70 and RPA32) and the

289 The known viral replication proteins, a telomere binding protein, and a

290 CTC1 has stronger structural similarity to Replication Protein A than the expected similarity to ye

291 soSSB dynamic behaviour is closer to that of Replication Protein A than to Escherichia coli SSB; a fe

292 nucleolin and is required for recruitment of replication protein A to DSBs, a marker of DSB processin

293 lication arrest, spontaneous accumulation of replication protein A to foci and chromatin, and a G2/M

294 eased AID phosphorylation and recruitment of replication protein A to S regions.

295 on does not simply originate from binding of Replication Protein A to the flap and sequestering it.

296 aborates with the ssDNA-binding complex RPA (replication protein A) to induce the sumoylation of reco

297 accumulate phosphorylated and ubiquitinated replication protein A (ubq-pRPA), the latter of which is

298 ETAA1 specifically interacts with RPA (Replication protein A) via two conserved RPA-binding dom

299 Efficient PCNA loading requires Replication Protein A, which is associated with the disp

300 By catalyzing the replacement of replication protein A with Rad51 on single-stranded DNA,