ライフサイエンスコーパス: reporter

1 d lineages by using a CRE-dependent TdTomato reporter.

2 creted embryonic alkaline phosphatase (SEAP) reporter.

3 g the same binding site but with a different reporter.

4 imals expressing NF-kappaB inducible imaging reporter.

5 rated an HPAT-targeted fluorescent secretion reporter.

6 th BiPNHP, a non-N-glycosylated GPI-anchored reporter.

7 MP signaling, measured by a pathway activity reporter.

8 n simply by detecting the status of excreted reporters.

9 achieve task with available substrate-based reporters.

10 ration with the corresponding combination of reporters.

11 MYC's effect on the expression of synthetic reporters.

12 nist JA-isoleucine (JA-Ile) only affect some reporters.

13 th metal isotopes of defined mass and act as reporters.

14 d with nuclear TCF-4 resulting in luciferase reporter activity and cyclin D1 expression.

15 down of these receptors antagonized TOPflash reporter activity and spheroid growth in vitro and eleva

16 The mouse SAN enhancer also directed reporter activity to the inflow tract in developing zebr

17 entified by measuring growth as a readout of reporter activity.

18 Using a recently developed MDR1-knockin reporter allele (Abcb1aAME), we found that constitutive

19 We additionally generated an RFX6(HA) reporter allele by gene targeting in wild-type H9 cells

20 Here, we developed a multicolor reporter allele system to genetically label and trace po

21 ion of three spectrally-distinct fluorescent reporters allowed us to evaluate different transfection

22 ion strategy, Preparative Cellular O-Glycome Reporter/Amplification (pCORA), that introduces 4-N(3)-B

23 e dual role both as an effective PET imaging reporter and as a suicide switch for CAR T cells.

24 ivation (CRISPRa) technology to induce a GFP reporter and endogenous gene expression.

25 transfer using gold nanoclusters as a signal reporter and gold nanoparticles conjugated with antibodi

26 ing proteins using a let-7 sensor luciferase reporter and identified the tRNA pseudouridine synthase,

27 RISPR screen using an endogenous cholesterol reporter and identify >100 genes involved in LDL-cholest

28 myonucleus expressing a fluorescent nuclear reporter and monitored its distribution among all myonuc

29 h various crRNA modifications, target types, reporters, and divalent cations.

30 ng and forthcoming fluorescent physiological reporters, and establish highly accessible, inexpensive

31 this CRISPR assay by cofocusing Cas12-gRNA, reporters, and target within a microfluidic chip.

32 t, thanks to innovations in live imaging and reporter animals.

33 However, currently available optical reporters are not capable of detecting small changes in

34 monstrated differential recombination; thus, reporters are not reliable proxies for another locus of

35 s with acute lung inflammation, the volatile reporters are released and expelled in breath at levels

36 ar-infrared (NIR) fluorescent macromolecular reporters are synthesized to specifically detect an immu

37 ouse ESCs, we assayed two massively parallel reporter assay (MPRA) libraries composed of binding site

38 e designed and executed a massively parallel reporter assay (MPRA) to investigate the effect of trans

39 In the massively parallel reporter assay (MPRA), short barcodes are counted by seq

40 gulate GNL3 expression using dual luciferase reporter assay and CRISPR interference experiment in hum

41 inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to

42 s validated kinetically using the nitrocefin reporter assay and in silico binding studies.

43 oth methods, indicating that the cannabinoid reporter assay can be used for an estimation of drug con

44 Bioinformatics analysis and luciferase reporter assay confirmed that miR-466o-3p directly targe

45 Finally, using the reporter assay developed, we find that the histone deace

46 We developed a two-color fluorescence reporter assay in Escherichia coli to overcome this prob

47 At the molecular level, luciferase reporter assay indicates that POGZ is a negative regulat

48 Reporter assay of MRP3 promoter (ABCC3pr) revealed that

49 bacteria using a riboswitch-controlled GFPuv-reporter assay revealed that each mutant had a deleterio

50 Luciferase reporter assay revealed that miR-124 post-transcriptiona

51 ays, we focused on E2F2, with the luciferase reporter assay revealing that it was a direct target for

52 Our reporter assay showed that volatile anesthetics isoflura

53 Here, we used a massively parallel reporter assay to measure the cis-regulatory consequence

54 Additionally, the outcome of the cannabinoid reporter assay was compared to the gold standard (LC-MS/

55 genome-wide small interfering RNA screen and reporter assay were used to identify host proteins requi

56 try, in situ hybridization, and a transgenic reporter assay, our results demonstrate a requirement fo

57 t cellular cytotoxicity (ADCC) activity in a reporter assay.

58 tested RIFINs and abolishes signalling in a reporter assay.

59 typic changes in a human embryonic stem cell reporter assay.

60 ition in WNT/beta-catenin signaling cellular reporter assay.

61 he wild-type, as demonstrated via luciferase reporter assay.

62 mparable to GCAUG in a trichromatic splicing reporter assay.

63 t an approach integrating massively-parallel reporter assays (MPRA) with cell-type-specific epigenome

64 Massively parallel reporter assays (MPRAs) can simultaneously measure the f

65 Massively parallel reporter assays (MPRAs) functionally screen thousands of

66 S inhibitors using MEIS dependent luciferase reporter assays and analysis in the ex vivo HSC assays.

67 c responses were determined using luciferase reporter assays and gene expression.

68 s negatively regulated by MYCN in luciferase reporter assays and its synthesis in neuroblastoma cells

69 Consistently, reporter assays combined with proteomic and immunopeptid

70 Luciferase reporter assays confirmed that chondrocyte enhancers cha

71 Luciferase-based reporter assays demonstrated target engagement at low nM

72 Reporter assays demonstrated that these LTR12C elements

73 High-throughput reporter assays dramatically improve our ability to assi

74 of distance and orientation in plasmid-based reporter assays of gene expression.

75 n of the top associated miRNAs by luciferase reporter assays of glucocorticoid-mediated transrepressi

76 Importantly, reporter assays showed that Gsx2 mediates opposing outco

77 Here, we use massively parallel reporter assays to directly measure the transcriptional

78 thod, Reg-Seq, that links massively parallel reporter assays with mass spectrometry to produce a base

79 l-time polymerase chain reaction, luciferase reporter assays, chromatin immunoprecipitation, docking

80 Using reporter assays, RNA-seq, ChIP-seq, and loss-of-function

81 y binds an unmethylated promoter used in the reporter assays.

82 using chromatin precipitation and luciferase reporter assays.

83 lidated the functionality of this site using reporter assays.

84 onal experiments, such as genome editing and reporter assays.

85 chromatin immunoprecipitation and luciferase reporter assays.

86 precipitation, cell invasion, and luciferase reporter assays; we measured gene expression, binding ac

87 owed that a green fluorescence protein (GFP) reporter becomes unstable when fused to the last 10 amin

88 rated the first replication competent tagged reporter birnaviruses, infectious bursal disease viruses

89 arry out a high throughput screen using Msi2-reporter blast crisis chronic myeloid leukemia (bcCML) a

90 describe a multiplexed bioluminescent repair reporter (BLRR) for non-invasive monitoring of DSB repai

91 sing numerous surface markers and transgenic reporters, but none is both universal and lineage restri

92 weight 162-410 g/mol) as PISTOL-based oxygen reporters by characterizing their calibration constants.

93 metry in conjunction with an engineered FRET reporter called VIral ProteasE Reporter (VIPER) to inves

94 % injected doses at 24 h postinjection), the reporters can be used for optical urinalysis of immunoac

95 d on enzyme-generating reporter cells; these reporters can detect specific mAb in hybridoma supernata

96 dependent transcription factor activity in a reporter cell assay.

97 NFAT DsRed IgE reporter cell binding was significantly increased on all

98 Herein, we combined reporter cell lines and activity-based protein profiling

99 se differences on FcgammaR-IgG interactions, reporter cell lines expressing common allotypes of human

100 ontent imaging screens against a panel of 15 reporter cell lines, which expressed a diverse set of fl

101 riggered ITAM signaling of corresponding CLR reporter cells.

102 naling domain expressed on enzyme-generating reporter cells; these reporters can detect specific mAb

103 d and known) using a rapid split fluorescent reporter characterization platform, and establish a libr

104 ding, we created a large library of isogenic reporter clones and identified reporter integration site

105 Using a CRISPR/Cas9 Zebrafish her6::Venus reporter combined with mathematical and in vivo experime

106 decreases fluidity of phase-separated TDP-43 reporter compartments in cells.

107 nsfection assays (Col3a1 promoter-luciferase reporter) confirmed PTH1R-mediated inhibition and Mkl-1-

108 emonstrate that the optimal placement in the reporter construct of enhancer sequences from a plant vi

109 . melanogaster S2 cells with dual luciferase reporter constructs validated predictions that miR-310s

110 Using 3'-UTR luciferase reporter constructs, CYP2B11-H3 showed markedly lower ge

111 /ionomycin-driven activation of a luciferase reporter containing BACH2/AP-1 target sequences from the

112 ixation, nucleic acid staining and catalysed reporter deposition fluorescence in situ hybridization (

113 latform combining the flavivirus sensor with reporter dyes for detection of chromatin condensation an

114 Reporters enable noninvasive monitoring of changes in ce

115 In worms, this reporter enables whole-brain imaging with faster kinetic

116 ldtype controls using a sarcomere functional reporter engineered by inserting tdTomato into the endog

117 By mapping our measurements of reporter expression at different genomic loci with multi

118 Thirty-two of these displayed reporter expression in restricted subsets of inner retin

119 Turning to a mouse model, Smoc2-GFP reporter expression indicates SMOC2 dynamically marks a

120 within promoter regions causes a decrease in reporter expression.

121 Collectively, the HOXA9 reporter facilitated the functional interrogation of the

122 shed on a large-scale and whether integrated reporter faithfully represents target biology.

123 Transgenic reporter fish demonstrated nuclear ESR activity in the d

124 pGTag (plasmids for Gene Tagging), contains reporters flanked by a universal CRISPR sgRNA sequence w

125 Using quinine as an endogenous reporter for pDNA intercalation, Raman imaging revealed

126 Using a transgenic reporter for RE transposition activity, we demonstrate i

127 esponses were also observed in agr-regulated reporters for leucocidin A (lukA, IC(50) 0.4-25 muM) and

128 the FBP in planta to build auto-luminescent reporters for the study of gene-expression and hormone f

129 tribution, we generated a live sphingomyelin reporter from Lysenin, a sphingomyelin-specific toxin fr

130 ify genes that, when overexpressed, induce a reporter (FUS1-HIS3) that responds to ERK-type pathways

131 Using a gfp reporter fusion, we demonstrated that induction of the l

132 is a target of miR-34a by a dural luciferase reporter gene assay in vitro.

133 Transactivation studies with a reporter gene assay revealed that gmAhr1a is one order o

134 Using a reporter gene assay, we demonstrated that C/P efficiency

135 Reporter gene assays demonstrated the ability of ICP0 to

136 quantitative real-time PCR, immunostaining, reporter gene assays, RNA-Seq, and two-photon glutamate

137 Ps, using GAL4-UAS-based in vitro luciferase reporter gene assays.

138 endent interaction with miRNAs, as proven by reporter gene assays.

139 or activate an antioxidant response element reporter gene due to the absence of a Keap1-binding moti

140 interrogation of genetic elements that alter reporter gene expression readout.

141 Using a reporter gene for eilA activation, we defined conditions

142 hylline-dependent down-regulation of the GFP reporter gene in a dose- and time-dependent manner.

143 ion of a downstream beta-glucuronidase (GUS) reporter gene in tobacco leaves.

144 therapies and 2) is correlated with optical reporter gene transduction of the brain.

145 The reporter gene used in the study is the green fluorescent

146 tor expressing the green fluorescent protein reporter gene was evaluated in the cat.

147 active in the 3' untranslated region of the reporter gene.

148 ne expression in the controlled setting of a reporter gene.

149 and prostate cancer cell lines, and elicited reporter-gene expression following intra-tumoural and in

150 mice, ~30% of GHRH neurons coexpressed both reporter genes in adult females, but not in males.

151 Using a mouse model with two reporter genes, we observed that, while GHRH(tdTom) neur

152 g two-photon imaging of fluorescent activity reporters has become a powerful tool for studying the fu

153 A few reporters have migrated to proof-of-principle clinical d

154 enhancer drove high expression of a betaGeo reporter in chondrocytes, but not in the hypertrophic zo

155 ased screen with an MLL2-dependent gene as a reporter in mouse embryonic stem cells.

156 GFP is frequently used as a reporter in proteasomal degradation assays.

157 crosslinking, and subsequently developed as reporters in a competitive displacement assay to identif

158 inized bacterial artificial chromosome (BAC) reporters in human fibroblasts, we found that ETV5 and c

159 protein of a given gene via dual fluorescent reporters in single, live cells of the yeast Saccharomyc

160 e editing technologies may enable the use of reporters in the context of genome-wide analysis and the

161 ith the need to provide a substrate to these reporters, including its high cost and non-uniform tissu

162 y of isogenic reporter clones and identified reporter integration sites in a massive and parallel man

163 Since the peptide-coupled reporter ion is precursor-specific while fragment ions o

164 fragment-ion series instead of only a single reporter ion.

165 fragmentation, as commonly observed in other reporter-ion-based approaches, such as TMT and iTRAQ.

166 the issue of ratio distortion observed with reporter-ion-based approaches.

167 show that 21-plex DiLeu tags generate strong reporter ions following HCD fragmentation of labeled pep

168 -specific glycans was achieved utilizing TMT reporter ions from HCD MS3 spectra.

169 uantifying proteins based on peptide-coupled reporter ions is a multiplexed quantitative strategy in

170 gh-resolution HCD MS/MS spectra via distinct reporter ions that differ in mass from each other by a m

171 echnologies that use elemental (heavy metal) reporter ions, such as mass cytometry (also known as CyT

172 pon tandem MS in the form of peptide-coupled reporter ions.

173 ce isobaric quantitative protein interaction reporter (iqPIR) technology which utilizes stable isotop

174 s whether tagging endogenous proteins with a reporter is a scalable strategy for generating cell mode

175 The functionality of the C-tag TNF reporter is based on the exposure of a cryptic epitope o

176 cause such clusters, which we call signaling reporter islands (SiRIs), can be modularly designed, the

177 Using nascent-transcription reporter knock-ins of YAP target genes, we show a strict

178 bow-KSHV replicated similarly to a prototype reporter-KSHV, KSHVr.219, and wild-type BAC16 virus.

179 line expressing an ERK-kinase translocation reporter (KTR) that enables live quantification of ERK a

180 dual genetic strategy in mice that restricts reporter labelling to a subset of the most quiescent lon

181 ease in ocular bioluminescence in the T cell reporter line.

182 he laminated murine retina to screen 92 lacZ reporter lines available through the Knockout Mouse Proj

183 Furthermore, GUS reporter lines for major GA20ox, GA3ox and GA2ox genes w

184 issue-specific expression using promoter:GUS reporter lines revealed their predominant expression in

185 We have established reporter lines, cultivation conditions, and imaging prot

186 sections from different bone types and 3 HSC reporter lines.

187 bred to express rod and/or cone fluorescent reporters, manifested a retinopathy and thin optic nerve

188 and have shown promise as metabolic chemical reporters (MCRs) for labeling inositol-containing glycoc

189 Web of Science and NIH Reporter metrics were also reviewed for each applicant.

190 We utilize fluorescent reporter mice (Otr(venus/+)) and find that cortical regi

191 Experiments with Glp1r reporter mice and a validated GLP-1R antibody indicated

192 Combining MP-designed fluorescent reporter mice and coherent anti-Stokes Raman scattering

193 ate tracking and transcriptome assessment in reporter mice establishes SOSTDC1-expressing T(FH) cells

194 PLVs from Cre-tdTomato reporter mice specific for progenitors of skeletal myocy

195 Here we develop bioluminescent circadian reporter mice that are Cre dependent, allowing the circa

196 ession in CAFs and by using Osx-cre;TdTomato reporter mice we confirm the presence and pro-tumorigeni

197 availability of hetero- and homozygous Gata3 reporter mice with an exceptionally bright fluorescent m

198 Using reporter mice with SOX2-driven, inducible gene expressio

199 -cell RNA-sequencing (scRNA-seq) and genetic reporter mice, we identified discrete lineages of intest

200 Using male D1tdTomato transgenic reporter mice, whole-cell patch-clamp electrophysiology,

201 e also detectable in the spleens of cytokine reporter mice.

202 he convenient cell isolation from Ccl17(E/+) reporter mice; it also exploited both CCL17-dependent an

203 , we examined the expression of a BSP-GFPtpz reporter mouse line during odontoblast differentiation,

204 Using a transgenic steroidogenesis-reporter mouse line we identify and characterize de novo

205 Here, we employed Gdf5-LacZ reporter mouse lines to assess the spatiotemporal activi

206 Analysis of reporter mouse lines TRPV1(PLAP-nlacZ) and TRPV1-Cre:tdT

207 In this study, we use a reporter mouse model to permanently "time stamp" NK cell

208 ing viral tracing, immunohistochemistry, and reporter mouse models.

209 Using reporter mouse strains, we show that DN T cells transit

210 Here, we develop a transgenic reporter mouse that allows dynamic measurement of CMA ac

211 Using a Notch reporter mouse, we discovered FCSCs localized within the

212 Moreover, in TPR-depleted cells reporter mRNAs generated from short transcripts accumula

213 rowth, polysome assembly, and translation of reporter mRNAs with structured 5'UTRs.

214 owed by hydrolysis to eliminate unmask redox reporter N-alkylated aminoferrocene (AAF) to monitor the

215 Matlab code before and after the addition of reporter nanoparticles containing IL-6 as target protein

216 dose-dependent activity against the nuclease reporter (nuc), which is under the control of the sae tw

217 al CD4 T cells, and cells expressing a Foxp3 reporter null allele revealed that the majority of Foxp3

218 Using a live-cell reporter of cell cycle phase and long-term imaging, we m

219 n cell lines with a barcoded transcriptional reporter of G protein signal transduction.

220 g an anti-poxvirus monoclonal antibody (as a reporter of protein expression), we showed that improved

221 e, thereby establishing survival itself as a reporter of RNAi.

222 er the use of their spin-labeled variants as reporters of conformational dynamics of membrane protein

223 owing the transgene to be used with numerous reporters of gene expression or neuronal dynamics.

224 Most such systems sort using fluorescent reporters on modified substrates or reactions that are r

225 unctional groups, inserting nuclei to act as reporters on their surrounding chemical environment.

226 ereas MYC-box III mutations delivered higher reporter output indicating that MBIII limits over-amplif

227 We developed a robust assay using gametocyte-reporter parasite lines to accurately measure the impact

228 Transfecting K562 cells with a reporter plasmid harboring the TOP2alpha/170 3'-UTR toge

229 es a fluorescent single stranded DNA (ssDNA) reporter present in the assay.

230 cement factor (EF), including suitable Raman reporter/probe molecules, and finally on c) good analyti

231 an ORF encoding NSP3 fused to a fluorescent reporter protein (i.e., UnaG, mRuby, mKate, or TagBFP).

232 n mice a cell fate mapping strategy based on reporter protein expression (ZsGreen) consecutive to pre

233 he MTS of BCO2a directed a green fluorescent reporter protein to the mitochondria when expressed in A

234 tion elements with beta-galactosidase as the reporter protein was designed and applied to cheap and p

235 -free system that can synthesize fluorescent reporters, protein nanocages, and the gene-editing nucle

236 S inhibition, and experiments using cellular reporter proteins have shown that proteasome inhibition

237 om mice expressing cell-specific fluorescent reporters purified by fluorescence activated cell sortin

238 in a novel WKY-hCD68-GFP monocyte/macrophage reporter rat strain.

239 , the pseudotyped doubly labeled fluorescent reporter red/green (R/G)-HIV-1 was used to identify and

240 A daf-2b splicing reporter revealed active regulation of this transcript t

241 e cell microscopy using chemical and genetic reporters revealed that PI(3)P stabilizes the digestive

242 cond, we implemented a parallel detection of reporter RNAs.

243 we used the same type of test cells for all reporters; second, we implemented a parallel detection o

244 erference (CRISPRi) with barcoded expression reporter sequencing (CiBER-seq).

245 To solve this problem, gold nanostar@Raman reporter@silica-sandwiched nanoparticles have been devel

246 A reporter strain of mice with enhanced green fluorescent

247 ) by utilizing bioluminescent B. burgdorferi reporter strains and in vivo imaging.

248 h to build a set of 10 versatile yeast-based reporter strains for studying human G protein-coupled re

249 promotes accumulation of a nuclear transport reporter, suggesting conserved NPC regulation by CN.

250 Using a dual fluorescent reporter system (NKX2-1(GFP);TP63(tdTomato)), we track a

251 ndent signaling in a receptor-specific yeast reporter system and in CXCR4-expressing human HEK293 tra

252 eloped and characterized a novel fluorescent reporter system for the assessment of cardiomyocyte matu

253 y developed luciferase-based DENV-2 protease reporter system in HeLa cells (DENV2proHeLa) was employe

254 EG-mediated protoplast transformation, a GFP reporter system that allows the rapid assessment of CRIS

255 f DOC was tested using an in vitro multiplex reporter system that evaluates modulation of the activit

256 We also developed a sensitive reporter system to quantify promoter leakiness and show

257 Here, we developed a reporter system to simultaneously monitor CDK4/6 and CDK

258 these ZFPs in a dual luciferase coincidence reporter system under the control of 4-kb promoter of hu

259 tudies of viral infection kinetics with this reporter system will enable basic investigations of viru

260 Using a luciferase reporter system, mutagenesis to disrupt and restore base

261 The outcome of the cell-based cannabinoid reporter system, which monitored the cannabinoid recepto

262 teracting fragments using a yeast two-hybrid reporter system.

263 f the exciton couplets observed for inductor-reporter systems might be correlated with an absolute co

264 ntial for engineering cell-based devices and reporter systems.

265 ificial antigen-presenting cells (aAPCs) and reporter T cells.

266 Two Component Signalling cytokinin-specific reporter (TCSn::GFP) closely matches intracellular cytok

267 plitude and lengthens the period of all four reporters tested while MJ and another JA agonist JA-isol

268 ned a novel CRISPR endoribonuclease Csy4/GUS reporter that enabled in situ visualization of HpasRNA-i

269 The system consists of GFP-based reporters that become fluorescent upon cleavage by recom

270 Using a TCR-transgenic Nur77-GFP reporter to distinguish "antigen-specific" from "bystand

271 generated C-tag TNF as a genetically encoded reporter to study TNF shedding at the single-cell level.

272 Cre/lox recombination with a linked Flp/frt reporter to track individual cell fates.

273 y designed, they permit a set of fluorescent reporters to be efficiently adapted for simultaneous mea

274 a2,3-sailoglycopeptides then generate unique reporters to distinctly differentiate those of alpha2,6-

275 s can be considered as reliable quantitative reporters to follow neurovascular coupling dynamics.

276 ansfer RNA (tRNA) accumulation activated ISR reporter transcription.

277 make morphological measurements in membrane reporter-transduced D1- and D2-MSNs and astrocytes, and

278 Using an IL-27 reporter transgenic mouse model, we show in this study t

279 n of the specific high-sensitivity enzymatic reporter unlocking (SHERLOCK) assay using the enzyme Cas

280 n the surface that is cleaved into a urinary reporter upon exposure to specific proteases overexpress

281 The nanosensors shed volatile reporters upon cleavage by neutrophil elastase, an infla

282 aracteristic Raman spectral features of each reporter used in different nanotags.

283 tional, translational, and posttranslational reporters using CRISPR interference (CRISPRi) with barco

284 by mobility shift assays and with luciferase reporters using mouse and human FXR isoforms.

285 gineered FRET reporter called VIral ProteasE Reporter (VIPER) to investigate heterogeneity of proteas

286 2 (SARS-CoV-2) pathogenesis and a luciferase reporter virus to demonstrate sera collected from SARS a

287 a reverse genetics system to generate a GFP reporter virus to explore severe acute respiratory syndr

288 Here, we generated a recombinant reporter virus, which we named "Rainbow-KSHV," that enco

289 NIH RePORTER was queried for new grants (R01, -03, -21) awar

290 Utilizing an optical RQC reporter we identify OTUD3 and USP21 as deubiquitylating

291 Due to the single-fluorophore nature of this reporter, we envision that this could find broad applica

292 Using a MIXL1 reporter, we explore mesoderm lineage-bias within the hu

293 Using the same reporter, we found decreased activity when ceRNA 3'UTRs

294 With an S1P(1) signaling reporter, we reveal that abluminal polarization shields

295 ing imaging methodologies and virus-specific reporters, we demonstrate that beta-coronaviruses utiliz

296 nal scanning with engineered transcriptional reporters, we establish a generalizable method for explo

297 g in vivo microscopy and transgenic vascular reporters, we observed that while bcar1-/- zebrafish sho

298 stematic implementation of such conformation reporters will allow to accelerate the decision process

299 yOFP, has emerged as a bright bioluminescent reporter with orthogonal substrate specificity to firefl

300 sed Cre/ER and the Cre-inducible fluorescent reporter YFP.