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1 hibit context dependent trans-activation or -repression activity.
2 h a C-terminal domain, resulting in additive repression activity.
3 lycine repeat domain of OsDrAp1 enhanced its repression activity.
4 red for both deacetylase and transcriptional repression activity.
5 s necessary and sufficient for its intrinsic repression activity.
6 ine- and proline-rich domain of OsDr1 had no repression activity.
7 he same surface of TBP that mediates the NC2 repression activity.
8 n3A interaction and thereby inhibits TIEG2's repression activity.
9 show that HERP has intrinsic transcriptional repression activity.
10  been shown to contain a Groucho-independent repression activity.
11 exhibit decreased or loss of transcriptional repression activity.
12 unchanged, reduced, or completely eliminated repression activity.
13  with WT1 and mediates WT1's transcriptional repression activity.
14  the cytoplasm and block its transcriptional repression activity.
15 P-1-like site in the TNF-RE is essential for repression activity.
16 ain but not with KRAB mutants that have lost repression activity.
17 d mSin3 and inactivate Mad's transcriptional repression activity.
18  with CRX/OTX2, consistent with a general co-repression activity.
19 by which mTORC1 controls LARP1's translation repression activity.
20 esting that the long CTD may modulate CtBP's repression activity.
21 ontacts with Not1 that are essential for its repression activity.
22 ) motif is required for this transcriptional repression activity.
23 viously described long-range transcriptional repression activity.
24 but strikingly, these mutations also cripple repression activity.
25  to the homeodomain confer activation versus repression activity.
26 as overexpression potentiates, SMRT-mediated repression activity.
27 ion of these sites altered its stability and repression activity.
28 istone deacetylases for full transcriptional repression activity.
29  TBX22 missense mutations result in impaired repression activity.
30 vide evidence that methylation augments Scd6 repression activity.
31 ad a negative impact on K-bZIP transcription repression activity.
32 clear protein that possesses transcriptional repression activity.
33 eins has both transcriptional activation and repression activity.
34 lated, exhibited the reduced transcriptional repression activity.
35  vivo promoter occupancy and transcriptional repression activity.
36 ain (aa 5-62), exhibits auto-transcriptional repression activity.
37 ined significant dephosphorylation-dependent repression activity.
38 moters, thereby exerting its transcriptional repression activity.
39 ity requires HCF-1 self-association and gene repression activity.
40 ne residues were required for efficient gene repression activity.
41       Knirps also possesses CtBP-independent repression activity.
42 e domains displays intrinsic transcriptional repression activity.
43 k together to phosphorylate PER and increase repression activity.
44 st significantly the ARMs, contribute to the repression activity.
45 titive inhibitor of RUNX2 and exhibited weak repression activity.
46 tive, rather than qualitative, deficiency in repression activity.
47 RX, however, it alleviates its transcription repression activity.
48 -motif could be a general modulator of their repression activity.
49 at sumoylation modulates its transcriptional repression activity.
50 that HoxA10 has Pbx1a-independent endogenous repression activity.
51 th transcriptional activators and endogenous repression activity.
52 t Ume1p binding to Rpd3p is required for its repression activity.
53  possible functional distinctions of the two repression activities.
54 NIC-1 and NIC-1 mutants retaining activation/repression activities.
55  deficient in transcriptional activation and repression activities.
56 physical interaction enhances KNAT7 and BLH6 repression activities.
57 g its critical function in mediating the CAR repression activities.
58 anscriptional activation and transcriptional repression activities.
59 , nonsteroidal GR ligand that possesses high repression activities against inflammatory mediator prod
60 rfering RNA inhibited BCL11B transcriptional repression activity and (3) MTA1 was specifically recrui
61 , although they possess comparable intrinsic repression activity and association with histone deacety
62 p-1 is required for its full transcriptional repression activity and function as an inhibitor of skel
63 (3) c-Abl inhibition reduces HDAC2-dependent repression activity and HDAC2 recruitment to the promote
64 onomeric state reduces Yan's transcriptional repression activity and impairs its function during embr
65 MO modification enhances p68 transcriptional repression activity and inhibits the ability of p68 to f
66 CDD component DET1 possesses transcriptional repression activity and physically interacts with two cl
67  GATA protein with intrinsic transcriptional repression activity and possibly a negative regulator of
68 hat GLI3 shows transcriptional activation or repression activity and subcellular localization similar
69 lex as a target for ataxin-1 transcriptional repression activity and suggest a novel pathogenic mecha
70 st that phosphorylation directly affects PER repression activity and that PER nuclear localization is
71 at AR possesses an intrinsic transcriptional repression activity, and AR interacts directly with SMRT
72 ation, DNA binding activity, transcriptional repression activity, and growth inhibitory effects of TI
73 dification, affecting both its stability and repression activity; and (5) treatment with Imatinib dec
74  (commonly found in human cancers) lost this repression activity; and (iii) this p53 repression activ
75          This result indicates that multiple repression activities are combined to exceed critical th
76 ctly binds to the Ssn6-Tup1 complex, and its repression activities are dependent upon Ssn6-Tup1 and h
77 nces between CtBP-dependent and -independent repression activities are poorly understood.
78                        The finding that both repression activities are simultaneously deployed sugges
79 n genetic switches, suggesting that multiple repression activities are utilized to provide quantitati
80 -DNA binding domains (MBDs), associated with repression activities, are sensitive to the substitution
81 ub-complexes that are required for Ssn6-Tup1 repression activity, are found to be required for Sfl1 r
82 e p130 pocket domain, which is important for repression activity, as well as an LXCXE sequence within
83 ivation but deficient in the transcriptional repression activity associated with c-Fos, did not induc
84       We further demonstrate DNA-binding and repression activities by the mammalian neural BEN-solo p
85 II sites potentiates VIPR-RP transcriptional repression activity by enhancing its nuclear translocati
86 lish that arginine methylation augments Scd6 repression activity by promoting eIF4G1-binding.
87 f life and exhibited reduced transcriptional repression activity compared to wild-type TBX18.
88 2 proteins all exhibited transactivation and repression activities, depending on the sequence context
89                                          One repression activity depends on dCtBP binding, and this f
90 aneously deployed suggests that the multiple repression activities do not function as cryptic 'backup
91 ent studies investigate modulation of HoxA10 repression activity during myelopoiesis.
92 the full-length mSin3A, exhibited a level of repression activity equivalent to, or greater than, the
93 tational analysis of CHF2 indicated that the repression activity for both transcription and myogenic
94 os-CtBP interactions do not abolish Ikaros's repression activity, implicating the involvement of addi
95 ibited compromised trans-activation or trans-repression activities in reporter gene assays.
96                             We studied giant repression activity in a CtBP mutant and find that this
97 served regions of RD3 that are important for repression activity in cell-based reporter gene assays.
98 n, nuclear localization, and transcriptional repression activity in cultured S2 cells.
99  importance of this putative transcriptional repression activity in neural cytotoxicity nor the trans
100       We also tested the modulation of their repression activity in response to specific plant metabo
101 the native Giant protein does not impair its repression activity in transgenic embryos.
102                    We have titrated out AmiC repression activity in vivo by increased AmiR production
103 o sites in vitro abolish Nanos translational repression activity in vivo.
104  not flank the HD is particularly crucial to repression activity in vivo.
105 , indicating that Rpd3 contributes to Knirps repression activity in vivo.
106 taining both CtBP-dependent and -independent repression activities is higher than that of the CtBP-in
107        The functional importance of multiple repression activities is not well understood, but the fi
108            We find that this transcriptional repression activity is abrogated by histone deacetylase
109                            The translational repression activity is found throughout the oocyte and a
110  general transcriptional repressor, and that repression activity is in the pseudoreceiver domain of t
111                               This intrinsic repression activity is masked by the AF-2 helix, which a
112 ressing E2F-regulated transcription, and its repression activity is not affected by trichostatin A, a
113 CpG), while MBD3 which has a dual activation/repression activity is not sensitive to the d(mCpG) d(hm
114  temperatures (30 degrees C and below), MogR repression activity is specifically inhibited by an anti
115                                    GmaR anti-repression activity is temperature dependent due to DegU
116  a central region, which harbours autonomous repression activity, is mainly responsible for this inte
117 ex is required for the known transcriptional repression activities mediated by UBC9 and SUMO1.
118 tween target mRNA cleavage and translational repression activities of Ago2.
119                Neither the apoptosis nor the repression activities of CtBP required histidine-315, su
120  required for both self-association and gene repression activities of HCF-1 were also required for ef
121 n experiments to examine the transcriptional-repression activities of the Hunchback (Hb) protein grad
122 nvolved only in the induction or only in the repression activities of the protein.
123 itical role in mediating the transcriptional repression activity of AR.
124 e region responsible for the transcriptional repression activity of ataxin-1 and participates in prot
125                          The transcriptional repression activity of AtERF7 is enhanced by HDA19 and A
126 tic environment promotes the transcriptional repression activity of c-Myc for gene-specific co-regula
127      We also provide details for testing the repression activity of CRISPRi using quantitative fluore
128 uents, HDACs contribute predominantly to the repression activity of CtBP1.
129                           Moreover, the full repression activity of CtIP requires a PLDLS domain that
130                                          The repression activity of CWH-3 was mapped to the region of
131 iate with and inactivate the transcriptional repression activity of E2F6, thereby subverting a critic
132 ction of FoxD3 and Grg4, the transcriptional repression activity of FoxD3 is enhanced by Grg4, and re
133 talytic residue, were important for the gene repression activity of HD2A.
134 on with 14-3-3 and dramatically enhanced the repression activity of HDAC7 in NIH3T3 cells, but not in
135 -dependent transactivation activity and auto-repression activity of IE2.
136 ic protease 1 attenuated the transcriptional repression activity of K-bZIP.
137 ays an important part in the transcriptional repression activity of K-bZIP.
138 action is important for the CtBP-independent repression activity of Knirps and is required for regula
139 hich is essential for the transactivation or repression activity of Miz1, resulted in hyperinflammati
140                                   Endogenous repression activity of other Hox-Pbx1a complexes require
141 dition to the inhibition of DNA binding, the repression activity of P3 on TR may also be mediated by
142                            Surprisingly, the repression activity of Pbx1 did not require homeodomain-
143 placing PML from PODs, failed to inhibit the repression activity of PML1, whereas the sumoylation-neg
144 e embryonic development and much of the gene repression activity of PRC1.
145                             We localized the repression activity of PU.1 to a small acidic N-terminal
146  leads to spatial and temporal regulation of repression activity of RGG-motif proteins remains unknow
147 domain of RUNX2 may contribute to the strong repression activity of RUNX2 for some target gene promot
148 ed on ELF4 promoter, but the transcriptional repression activity of RVE5 is weaker than that of CCA1.
149                        Here we show that the repression activity of RXR correlates with its binding t
150 ole of arginine methylation in regulation of repression activity of Scd6, a conserved RGG-motif prote
151 The importance of Arg-57 methylation for the repression activity of SHP provides a molecular basis fo
152  first time that Pak1 promotes transcription repression activity of Snail from E-cadherin, occludin,
153 a N-terminal motif that is essential for the repression activity of some regulators in ethylene signa
154 nding domains of StBEL5 or POTH1 blocked the repression activity of StBEL5 or POTH1, respectively.
155  StBEL5-POTH1 heterodimer also abolished the repression activity of StBEL5, POTH1, and the StBEL5-POT
156 evidence for the gene-specific transcription repression activity of Tet2 via histone deacetylation an
157 ction, which leads to enhanced transcription repression activity of the ARF6/8-IAA9 complex but impai
158 e leaves, whereas the E2F1 site counters the repression activity of the E2F2 element in young leaves.
159 is of IRE binding affinity and translational repression activity of the resulting IRP1 mutants showed
160              This motif is essential for the repression activity of these proteins in transgenic embr
161  nucleotide sequence and does not affect the repression activity of WT1.
162 l revealed that p.Ser420Phe CRY2 had reduced repression activity on CLOCK:BMAL1-driven transcription
163 sphatases, the control of ScoC transcription repression activity plays a crucial role in the initiati
164 ng E2A-mediated gene transcription, but full repression activity required the presence of two conserv
165 function also lost most of its transcription repression activity suggesting that interaction with the
166 HD fingers or bromodomains failed to restore repression activity, suggesting high specificity in thei
167  A treatment reduced Dermo-1 transcriptional repression activity, suggesting that histone deacetylati
168  that the CTD may help provide a spectrum of repression activity suitable for developmental programs.
169  greater DNA binding activity and a stronger repression activity than do the respective homodimers.
170 er, this study identifies a P-body-dependent repression activity that coordinates with known transcri
171 ong form of Atrophin-2 has a transcriptional repression activity that is not found in the other Atrop
172 main protein had independent transcriptional repression activity that mapped to the C-terminal region
173             BRCA1 exerts its transcriptional repression activity through interaction with the transcr
174 ing deletion constructs of SSX1 we localized repression activity to 33 amino acids at the C-terminus.
175  Knirps synergizes with the CtBP-independent repression activity to potently repress promoter element
176  DR4 promoter and Hh requires an intact GLI3-repression activity to silence DR4 expression.
177 tro mapping studies define the transcription repression activity to the PHD finger domain of the chic
178 ted SSX-KRAB domains to specifically measure repression activity, using a previously characterized KO
179           Using this approach, we found that repression activity was highly conserved and likely the
180 this repression activity; and (iii) this p53 repression activity was mediated at least in part by the
181                          TRP transcriptional repression activity was specifically reduced by mutation
182  separately analyze the components of Knirps repression activity, we elucidated the specific repressi
183 To initiate mechanistic studies of the giant repression activity, we have identified a minimal repres
184 ers showed that Meq/Meq homodimers exhibited repression activity, whereas Meq/Jun heterodimers showed
185              OsVOZ1 displays transcriptional repression activity while OsVOZ2 confers transcriptional
186 rated that SQU possesses both activation and repression activities, while KEW acts only as an activat

 
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