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1 al regulation of Ptch1, a known Hh-signaling repressor.
2 og of Escherichia coli OmpR, was a virulence repressor.
3 te the DNA-binding activities of the lactose repressor.
4 r6, a basic helix-loop-helix transcriptional repressor.
5 chromatin and functions as a transcriptional repressor.
6 epends on MNT, a MYC-related transcriptional repressor.
7 ch putatively functions as a transcriptional repressor.
8 In this study, we create 41 inducible anti-repressors.
9 CH1 and PURalpha, two androgen receptor (AR) repressors.
10 es by binding to TetR family transcriptional repressors.
11 for engineering systems of non-natural anti-repressors.
12 thy further suggests crosstalk between these repressors.
13 -protein interaction between BCL6 and its co-repressors.
14 s including association with transcriptional repressors.
15 terplay between transcription activators and repressors.
16 C transcription factors that cannot bind JAZ repressors.
17 ssion via the degradation of transcriptional repressors.
18 ers that was attributable to known and novel repressors.
19 ional activators and CRY-PER transcriptional repressors.
20 ely used naturally occurring transcriptional repressors.
21 8) or CBFA2/RUNX1 partner transcriptional co-repressor 3 (Cbfa2t3, also called Mtg16), and derived th
24 studied, less is known about transcriptional repressors acting directly on IFN-I regulatory regions.
25 ve distribution of its plasmid partition and repressor activities, using a ParA with an alanine subst
27 allele is compromised for partition, but its repressor activity is dramatically improved so that it b
29 1 territory, correlates with increased Gli3 repressor activity, a Hoxd negative regulator, resulting
31 G sites within the aryl-hydrocarbon receptor repressor (AHRR) associate with PTSD after adjustment fo
32 lloblastomas with high expression of the AHR repressor (AHRR) exhibited a significantly worse prognos
33 d the emergence and evolutionary dynamics of repressor alleles after P-elements invaded the Drosophil
34 nsertion in a piRNA cluster, indicating that repressor alleles are produced by de novo insertion at a
36 eolytic cleavage of the LexA transcriptional repressor, allowing expression of > 40 gene products inv
41 of YAP nuclear function as a transcriptional repressor and highlights how loss of contact inhibition
42 of Lactococcus lactis, controlled by the CI repressor and the modulator of repression (MOR) antirepr
43 lian Gli proteins to nuclear transcriptional repressors and by activating the full-length Ci or Gli p
45 from the reduced formation of Gli2 and Gli3 repressors and early depletion of adenylyl cyclase III i
46 ycomb group (PcG) of proteins are epigenetic repressors and lamin A interactors, primarily involved i
47 by the appearance of quiescent cell-specific repressors and rewiring of the interactions of protein-f
48 ocesses driving oscillations in an activator-repressor architecture and allows us to make predictions
49 urprising discovery that, in the nucleus, co-repressors are dramatically more abundant than co-activa
50 YC) activators and PERIOD-TIMELESS (PER-TIM) repressors are feedback loop components whose transcript
52 indings describe CHD4, a classically defined repressor, as positive regulator of transcription and su
53 netic architectures represent a nascent anti-repressor based transcriptional programming structure.
54 increased expression of the transcriptional repressor Bcl6 and that Bcl6 is required for differentia
56 mRNA extension encoding a Nab1 translational repressor binding site in a CAO knockout line it was pos
57 nal scanning of the CRISPRi KRAB maps the co-repressor binding surface and identifies substitutions t
59 antly decreases the binding affinity for the repressor Broad, driving differential allele-specific nu
62 osome thus serves not only as a general gene repressor, but also as a repressor of all transcription
64 ctivator, YAP functions as a transcriptional repressor by interacting with the multifunctional transc
65 tringent activation requirements function as repressors by blocking promoter access of SHP-bound conf
66 ntagonizing the activity of another group of repressors called PHYTOCHROME-INTERACTING FACTORs (PIFs)
67 script levels using a CRISPR-based synthetic repressor can be an effective strategy for AAV-based CRI
69 odestly increased expression of the ATXN1 co-repressor Capicua (Cic) in anterior cerebellar Purkinje
70 ect the ERK-dependent control of the HMG-box repressor Capicua (Cic), which plays critical roles in d
71 A decay factors, including the translational repressors CAR-1/LSM14 and CGH-1/DDX6, and the decapping
72 Small molecule inhibition of one of these repressors, CDC7, by XL413 and other inhibitors increase
74 on as master regulators of this multisubunit repressor complex (E2F-Rb-HDAC) to reverse its suppressi
78 s, both RBR and E2FB are abundant and form a repressor complex that is reinforced by an autoregulator
81 ARTNER A, further elevate the amount of this repressor complex, leading to reduced leaf cell number.
88 rice FERTILIZATION-INDEPENDENT SEED-POLYCOMB REPRESSOR COMPLEX2 component, in MADS78 and 79 mutants a
89 4 proteins assemble into florigen activation/repressor complexes (FACs/FRCs), which regulate transiti
90 Mdm4 interacts with members of the Polycomb Repressor Complexes and supports the ubiquitination of H
91 mpanied by loss of recruitment of epigenetic repressor complexes containing PRMT5 and either histone
92 rs via the recruitment of co-activator or co-repressor complexes that epigenetically regulate gene ex
93 lar level, TBL1XR1 mutants co-opt SMRT/HDAC3 repressor complexes toward binding the MB cell transcrip
96 vealed a major role of the carbon catabolite repressor CRE-1 in regulating the expression of major fa
97 al activators (BMAL1 and CLOCK) and negative repressors (CRYPTOCHROMEs (CRYs) and PERIODs (PERs)).
98 mice, while deletion of the transcriptional repressor (Deltargg3) increased the percentage of coloni
100 ectly by facilitating degradation of Aux/IAA repressors, direct ETTIN-auxin interactions allow switch
101 d plants that express a fusion of TCP15 to a repressor domain (pTCP15::TCP15-EAR) had shorter stamens
104 ourse of our studies, we discovered that the repressor domain SID (SIN3-interacting domain) derived f
105 cell lines used, SID is superior to the KRAB repressor domain, which serves routinely as a transcript
107 2F members, in particular activator E2F1 and repressors E2F7 and E2F8, form a feedback circuit at the
109 arget of hypoxia through the transcriptional repressor element 1-silencing transcription factor, link
112 or forced APC/C activation by targeting its repressor EMI1 are both potential therapeutic approaches
114 -ADABA is known to induce the MocR/GabR-type repressor EnuR, which controls the expression of many ec
115 e underlying mechanism of transcriptional co-repressor ETO2 during early erythropoiesis and hemoglobi
117 ur study reveals that a transcription factor-repressor feedback module employs tight regulation of Tf
119 variation in expression levels of the floral repressor FLOWERING LOCUS C (FLC) leads to differences i
122 e with neuron-specific expression of a super-repressor form of the NF-kappaB inhibitor (IkappaBalpha-
124 r Zur binds to DNA tightly in its metallated repressor form to Zur box operator sites, repressing the
125 onditions, exists in its metal-deficient non-repressor forms having no significant affinity with Zur
130 bly due to the activation of transcriptional repressor genes such as Cbfa2t3 and Jdp2 The large numbe
133 hough changes in the state of activators and repressors has been characterized, how their status is t
135 Recently, non-natural transcription factors (repressors) have been engineered and employed in synthet
136 ggered overexpression of the transcriptional repressor Hes-related family BHLH transcription factor w
137 n this repressor system, two transcriptional repressors-heterochromatin protein 1 (HP1a) and Kruppel-
142 IAA33 competes with the canonical AUX/IAA repressor IAA5 for binding to ARF10/16 to protect them f
148 ins MvaT and MvaU act coordinately as global repressors in Pseudomonas aeruginosa by binding to AT-ri
149 ally improved so that it behaves as a "super-repressor." In vitro, ParA(R351A) binds and hydrolyzes A
150 gnals on short photoperiods induce circadian repressors including DEC1, suppressing BMAL2 and the EYA
151 ent in limb buds devoid of GLI activator and repressor, indicating that their activity is primarily r
153 , and Botts-Morales formalisms), and genetic repressor kinetics, thereby allowing a large class of mo
154 on of the well-characterized transcriptional repressor Kruppel-like factor 3 (KLF3), which, in turn,
156 rigen gene FTa1 and repression of the floral repressor LF Our results establish the conserved importa
157 neuron-specific expression of IkappaB super-repressor mitigated behavioral and pathologic changes in
161 miR-US5-2 downregulates the transcriptional repressor NGFI-A binding protein (NAB1) to induce myelos
162 ssion (EAR) domain-dependent transcriptional repressors: NO abolished this activity for SRG3 but not
163 her these results identify TFII-I as a novel repressor of a subset of TGFbeta-responsive genes throug
165 y as a general gene repressor, but also as a repressor of all transcription (genic, intragenic, and i
168 gs identify FOXF1 as a novel transcriptional repressor of ATX and demonstrate that loss of FOXF1 prom
169 MSCs via its role as a novel transcriptional repressor of autocrine motility-stimulating factor Autot
171 and an unexpected role of XBP1u as a potent repressor of both XBP1s and ATF6-mediated activation.
172 BRASSINOSTEROID-INSENSITIVE 2 (BIN2), a key repressor of brassinosteroid signaling, to repress hypoc
173 active protein synthesis and that 4E-BP1, a repressor of cap-dependent protein translation, specific
174 TED (RBR), a sugar-dependent transcriptional repressor of cell proliferation, depletes meristematic a
177 nscription factor that functions as a global repressor of fungal secondary metabolism in Aspergillus
179 rectly stimulates transcription of BCL11A, a repressor of gamma-globin transcription, by binding to i
180 specific tRF-5' tRF-Gly-GCC, or tRF-GG-as a repressor of genes associated with the endogenous retroe
182 ZBED2 is a sequence-specific transcriptional repressor of IFN-stimulated genes, which occurs through
183 The transcription factor ZBED6 acts as a repressor of Igf2 and affects directly or indirectly the
184 nding transcription activator3 (CAMTA3) is a repressor of immunity-related genes but an activator of
185 insights into YAP as a broad transcriptional repressor of key regulators of the cell cycle, in turn i
191 RR3b(H6) appears to act as a transcriptional repressor of multiple predicted circadian clock genes, i
196 The apocarotenoid acted in parallel to the repressor of photomorphogenesis, DEETIOLATED1 (DET1), to
197 OsRAV9/OsTEM1 has a conserved function as a repressor of photoperiodic flowering upstream of the flo
198 Here we identify TGF-beta1 as a principle repressor of PPM1A, as conditional renal tubular-specifi
199 her neuronal overexpression of 4E-BP1, a key repressor of protein translation, can protect against mi
200 ing peptide, Phr*pLS20, inactivates the anti-repressor of RcopLS20, named RappLS20, which belongs to
203 The 5-methylcytosine DNA glycosylase/lyase REPRESSOR OF SILENCING 1 (ROS1)-mediated active DNA deme
211 is a nucleoid structuring protein and global repressor of virulence and horizontally-acquired genes i
212 in the biochemical network of activators and repressors of cytoskeleton dynamics have been invoked to
215 circSamd4 associated with PURA and PURB, two repressors of myogenesis that inhibit transcription of t
216 SUPPRESSOR OF PHYA (SPA), one of the central repressors of photomorphogenesis, is critical for mainta
217 Collectively, FBXO44/SUV39H1 are crucial repressors of RE transcription, and their inhibition sel
218 CHMP2BIntron5 expression, we have uncovered repressors of retrovirus (RV) activity as modifiers of C
219 RF6, ERF016 and ORA59 appear to act as trans-repressors of RPW8.1, with OAR59 being able to directly
220 repressor, REST, function as transcriptional-repressors of SPINK1, and AR-antagonists alleviate this
224 es controlled as a unit, usually by the same repressor or activator gene, is known as a regulon.
225 H) mutations, editing of transcriptional HbF repressors or their binding sites and/or regulating epig
230 Here we show that Spen, an Xist-binding repressor protein essential for XCI , binds to ancient r
233 ctor) protein, a neuronal gene transcription repressor protein, is responsible for NE gene expression
235 binds auxin, leading to dissociation from co-repressor proteins of the TOPLESS/TOPLESS-RELATED family
236 All 16 maize auxin/indole-3-acetic acid repressor proteins were degraded in response to auxin wi
237 as a temperature-responsive transcriptional repressor, providing rhythmicity and temperature respons
238 on plants suggests a role as transcriptional repressor, putatively targeting pathways involved in cel
242 identify a critical role for the epigenetic repressor REST corepressor 1 (CoREST) in promoting Treg
243 Here, we reveal that the transcriptional repressor role of SerRS is inactivated under hypoxia thr
245 hology, when supplemented by constitutive Ci repressor, showing that Hh can signal normally in the ab
246 lated by the activity of the transcriptional repressor, SinR, and its inactivation by its primary ant
249 en identified, including the transcriptional repressor SPEN(1-3), the loss of which has been associat
250 that direct repression of WOX9 by WUS clade repressor STF/LAM1 is required for correct blade archite
251 the KRAB domains, discover that Homeodomain repressor strength is collinear with Hox genetic organiz
254 l activator, Tbx5, and T-box transcriptional repressor, Tbx3, determined the molecular and functional
255 c plaques, inclusions of the transcriptional repressor TDP-43, angiopathy, neuron loss and gliosis.
258 mRNA turnover that binds DCP2, but also as a repressor that binds MARF1 to prevent the decay of MARF1
260 expected role for Blimp-1, a transcriptional repressor that constrains autoimmunity, as an upstream p
261 (CIC) is a highly conserved transcriptional repressor that is differentially regulated through mitog
262 ompeting with H-NS, a global transcriptional repressor that oligomerizes on DNA to form filaments and
265 oncoding regulatory activities, as a cis-DNA repressor that regulates neighboring genes and as a lncR
266 asic helix-loop-helix-orange transcriptional repressor that regulates neurogenesis in several develop
267 e encodes a C2H2 zinc-finger transcriptional repressor that regulates the floral organ number in the
269 uence (FRS) 7 and FRS12, two transcriptional repressors that accumulate in short-day conditions, as r
271 omplemented by 14 additional engineered anti-repressors that respond to the ligand isopropyl beta-d-1
272 ic exclusion conferred by the phage immunity repressor, the phenotype observed in B3-like lysogens su
273 rogen receptor-alpha (ER) transcriptional co-repressor through leucine/isoleucine-rich motifs that ar
274 inactivated FOXA1 binding to its interacting repressors TLE3, HDAC7, and NFIC, thereby blocking FOXA1
276 ormation transformed Orb2 from a translation repressor to an activator and "seed" for further transla
280 e super-enhancers by tethering transcription repressors to enhancers significantly reduces target gen
281 ue to the intrinsic challenges of connecting repressors to gene upregulation in complex cell types wi
282 romatin enables a network of transcriptional repressors to regulate expression levels of class A ARF
284 , including C2H2 zinc finger transcriptional repressor TraesCS5A02G542800 upregulated in developing s
285 blishes a mechanism by which transcriptional repressor TREE1 interacts with EIN3 to inhibit shoot gro
287 een the transcription factor TEAD and its co-repressor VGL4, both playing a central role in the Hippo
289 vators and Rgg3 proteins are transcriptional repressors, we propose that both are capable of transcri
290 f-activating activator that also activates a repressor, which inhibits the activator and diffuses to
291 ng with the induction of the CcMADS19 floral repressor, which prevents the activation of the floral p
293 degrades Rim4, an amyloid-like translational repressor whose timed clearance regulates protein produc
295 a dichotomous transcriptional activator and repressor, with a non-canonical deacetylase-independent
296 gether with the modern clade transcriptional repressor WOX genes in embryogenesis and meristems maint
297 nisms by direct interaction of activator and repressor WOX genes may be required for cell proliferati
299 Furthermore, repurposing the iron-dependent repressor YtgR underscores the fundamental importance of
300 eport that the BTB-ZF family transcriptional repressor Zbtb20 negatively regulates CD8 T cell metabol