1 atment, methodological challenges, and novel
research designs).
2 hould be considered both in patient care and
research design.
3 s, but has never been tested with a rigorous
research design.
4 es and discuss ways they can be addressed in
research design.
5 he original reports according to the type of
research design.
6 psychopathology provide valuable focuses for
research design.
7 hould be considered a virtual requirement in
research design.
8 by ethical considerations that constrain the
research design.
9 and 2.21% using our difference-in-difference
research design.
10 ing disaggregated data, actions which impact
research design.
11 hered through a multisited and mixed-methods
research design.
12 bservational data, however, requires careful
research design.
13 ctices in social science and used a credible
research design.
14 ed by unmeasured factors in an observational
research design.
15 this paper emerged from within the inductive
research design.
16 tive and theoretically appropriate for their
research design.
17 nd the remaining eight used a combination of
research designs.
18 lausibility from different but complementary
research designs.
19 ulation level should be assessed with robust
research designs.
20 ol conditions that call for forward-thinking
research designs.
21 Trends suggest a growing maturity in the
research designs.
22 By adopting a cross-sectional
research design,
a purposive sampling technique was used
23 Differences in topic and
research design account for a small part of the relation
24 llow-up genome scan, which used a consistent
research design across studies and examined the largest
25 4) How has
research design affected the results of studies of bupre
26 sex as a biologic variable be factored into
research design,
analyses, and reporting of vertebrate a
27 RESEARCH DESIGN AND A cannula was placed in the lateral
28 RESEARCH DESIGN AND A cross-sectional study of 1,066 men
29 RESEARCH DESIGN AND A nested case-control analysis was c
30 RESEARCH DESIGN AND A total of 11 intensively treated ty
31 RESEARCH DESIGN AND About 2% of LEW*1WR1 rats develop sp
32 RESEARCH DESIGN AND About 2% of LEW.1WR1 rats develop sp
33 RESEARCH DESIGN AND Ad*VEGF and Ad*Ang1 were intramyocar
34 RESEARCH DESIGN AND Adipocytes from intra-abdominal/peri
35 RESEARCH DESIGN AND Adult mice deficient in either p130
36 RESEARCH DESIGN AND Adult transgenic zebrafish were inje
37 RESEARCH DESIGN AND After congenic transfer of the NOD H
38 RESEARCH DESIGN AND After excluding subjects who reporte
39 RESEARCH DESIGN AND All studies were performed using per
40 RESEARCH DESIGN AND An expression plasmid of plasminogen
41 ic approaches and discuss factors related to
research design and analysis that can enhance the inform
42 RESEARCH DESIGN AND Angiogenesis (capillary density) and
43 RESEARCH DESIGN AND Apoptosis, albuminuria, ROS generati
44 tely require incorporation of both stringent
research design and assessment in the clinical context i
45 RESEARCH DESIGN AND At baseline, 301 type 2 diabetic par
46 RESEARCH DESIGN AND At baseline, 32 male adult cynomolgu
47 RESEARCH DESIGN AND beta-Cell mass, beta-cell proliferat
48 RESEARCH DESIGN AND Blood glucose, insulin, lipid measur
49 RESEARCH DESIGN AND Both human umbilical vein endothelia
50 RESEARCH DESIGN AND C57BL/6 Ldlr(-/-) mice were cross-br
51 RESEARCH DESIGN AND Cav1 knockout and wild-type C57BL/6
52 RESEARCH DESIGN AND Conscious 60-h fasted canines were s
53 Using a quasiexperimental
research design and daily data on EEC from 2007 to 2015,
54 forts are needed to coordinate and integrate
research design and data acquisition and interpretation
55 r approaches reflect prevailing paradigms of
research design and data analysis and suggest future res
56 RESEARCH DESIGN AND Differentiated 3T3-L1, Simpson-Golab
57 RESEARCH DESIGN AND Dogs were fed a regular diet (lean)
58 RESEARCH DESIGN AND Effects of each therapy were tested
59 RESEARCH DESIGN AND Effects of high glucose on wound hea
60 RESEARCH DESIGN AND Eight subjects with risk-conferring
61 RESEARCH DESIGN AND ELVs released from adipose tissue we
62 d and opportunity for innovation in surgical
research design and evaluation.
63 However, an appreciation of optimal
research design and execution is a prerequisite and shou
64 RESEARCH DESIGN AND Experimental mice were pregnant fema
65 RESEARCH DESIGN AND Expression of RAGE, S100A8, S100A12,
66 These recommendations will improve
research design and facilitate study combinations, betwe
67 RESEARCH DESIGN AND Fifteen robustly associated type 2 d
68 RESEARCH DESIGN AND For fine-mapping, we sequenced WFS1
69 RESEARCH DESIGN AND For islet labeling, we adapted the F
70 RESEARCH DESIGN AND For this study, 22 type 1 diabetic s
71 RESEARCH DESIGN AND FOXO1 was tested in vivo by DNA bind
72 RESEARCH DESIGN AND From the Multi-Ethnic Study of Ather
73 rms of the health care enterprise combine in
research design and funding, as the latter bears the imp
74 RESEARCH DESIGN AND Gene-targeted mutations of either It
75 RESEARCH DESIGN AND Gene-trap techniques were used to ab
76 RESEARCH DESIGN AND Genotypic data from a genome-wide as
77 RESEARCH DESIGN AND Healthy human volunteers (n = 14) we
78 RESEARCH DESIGN AND Here, we examine the half-life of ad
79 RESEARCH DESIGN AND HIP rats were treated with sitaglipt
80 RESEARCH DESIGN AND ICR mice were food restricted by 50%
81 RESEARCH DESIGN AND In all, 5,290 single nucleotide poly
82 RESEARCH DESIGN AND In dietary-obese C57BL/6J mice, sodi
83 RESEARCH DESIGN AND In order to separate the transient n
84 RESEARCH DESIGN AND In this study, 10 obese diabetic and
85 RESEARCH DESIGN AND In this study, the anorectic effects
86 RESEARCH DESIGN AND In this study, we analyzed the pheno
87 RESEARCH DESIGN AND In vivo testing of mechanical and th
88 Using a high-frequency
research design and individual fixed effects, we find th
89 RESEARCH DESIGN AND Male C57BL/6 mice were fed a high-fa
90 RESEARCH DESIGN AND Male Grp78(+/-) mice and their wild-
91 RESEARCH DESIGN AND MCK-IL10 and wild-type mice were fed
92 Although there is variability in
research design and measured outcomes, evidence supports
93 RESEARCH DESIGN AND METHODS Seven studies of the STAMPEE
94 RESEARCH DESIGN AND METHODS Ten single nucleotide polymo
95 RESEARCH DESIGN AND METHODS- TLR4 gene expression and pr
96 RESEARCH DESIGN AND METHODS-Rats were cannulated and bil
97 Research design and methods: We established lymphoblasto
98 RESEARCH DESIGN AND METHODS; Genetic analysis of HLA-DRB
99 RESEARCH DESIGN AND METHODS; The glucoregulatory actions
100 RESEARCH DESIGN AND Mice (n = 10) were fed a control (10
101 RESEARCH DESIGN AND Mice deficient in the catalytic subu
102 RESEARCH DESIGN AND Mitochondrial matrix and membrane fr
103 RESEARCH DESIGN AND Mstn(Ln/Ln) mice were weaned onto a
104 RESEARCH DESIGN AND Muscle biopsies were obtained basall
105 RESEARCH DESIGN AND Mutations were directly sequenced, a
106 RESEARCH DESIGN AND Nephrin expression in human pancreas
107 RESEARCH DESIGN AND Nine subjects with the E23K genotype
108 RESEARCH DESIGN AND Nonsmokers (n = 18, aged 20 +/- 0.5
109 RESEARCH DESIGN AND Of 32,826 Nurses' Health Study parti
110 RESEARCH DESIGN AND Offspring of ethylnitrosurea-mutagen
111 RESEARCH DESIGN AND Participants from the Epidemiology o
112 RESEARCH DESIGN AND Participants were 1,399 women (39% b
113 RESEARCH DESIGN AND Perifusion analyses of isolated Munc
114 RESEARCH DESIGN AND Persistence of Tregs was assessed by
115 RESEARCH DESIGN AND Placental samples were analyzed usin
116 application of interdisciplinary methods to
research design and practice (e.g., developing research
117 RESEARCH DESIGN AND Pregnant female Sprague-Dawley rats
118 RESEARCH DESIGN AND Rats exposed to recurrent insulin-in
119 RESEARCH DESIGN AND Rats were depleted of KCs by adminis
120 RESEARCH DESIGN AND Rats were fasted overnight.
121 RESEARCH DESIGN AND Relevant studies published before Ju
122 RESEARCH DESIGN AND Serum and adipose tissue biopsies we
123 RESEARCH DESIGN AND SIM1 was sequenced in 96 individuals
124 RESEARCH DESIGN AND Since 1993, the Diabetes Autoimmunit
125 stigators abstracted study details including
research design and sonographic imaging technique to det
126 Detailed
research design and statistical methods are presented in
127 RESEARCH DESIGN AND Steady-state kinetic parameters of A
128 RESEARCH DESIGN AND Sural nerve myelinated fiber density
129 RESEARCH DESIGN AND TCF7L2 expression in rodent islets a
130 RESEARCH DESIGN AND The CRR was evaluated in rats and mi
131 RESEARCH DESIGN AND The Diabetes Audit and Research in T
132 RESEARCH DESIGN AND The effect of preoptic area administ
133 RESEARCH DESIGN AND The INS gene was sequenced in 16 Fre
134 RESEARCH DESIGN AND The relationships of MetS or its com
135 RESEARCH DESIGN AND The Type 1 Diabetes Genetics Consort
136 RESEARCH DESIGN AND The Women's Antioxidant and Folic Ac
137 RESEARCH DESIGN AND Thirty-four G1/S regulatory proteins
138 RESEARCH DESIGN AND This was a population-based study (M
139 RESEARCH DESIGN AND Tissue gene and protein expression p
140 RESEARCH DESIGN AND To address this, we fed wild-type (W
141 RESEARCH DESIGN AND To distinguish neurons that mediate
142 RESEARCH DESIGN AND To evaluate the roles of AMPK and Ak
143 RESEARCH DESIGN AND To identify key metabolic pathways t
144 RESEARCH DESIGN AND To investigate the role of Isl-1 in
145 RESEARCH DESIGN AND Twelve young lean, 12 young obese, 1
146 RESEARCH DESIGN AND Twenty-two insulin-naive subjects wi
147 RESEARCH DESIGN AND Using data from an ongoing genome-wi
148 RESEARCH DESIGN AND Using data from an ongoing GWAS of p
149 RESEARCH DESIGN AND Using matrix-targeted photoactivatab
150 RESEARCH DESIGN AND Using miRNA microarrays, we profiled
151 RESEARCH DESIGN AND We analyzed T1-weighted magnetic res
152 RESEARCH DESIGN AND We analyzed the capacity of beta-cel
153 RESEARCH DESIGN AND We analyzed the morphology of the pa
154 RESEARCH DESIGN AND We applied multicolor flow cytometry
155 RESEARCH DESIGN AND We assessed adaptive beta-cell proli
156 RESEARCH DESIGN AND We assessed skeletal muscle microvas
157 RESEARCH DESIGN AND We compared the expression of VEGF-A
158 RESEARCH DESIGN AND We determined cytokine profiles in c
159 RESEARCH DESIGN AND We developed a protease-resistant du
160 RESEARCH DESIGN AND We developed an mfat-1 transgenic mo
161 RESEARCH DESIGN AND We evaluated 50 juvenile rats with D
162 RESEARCH DESIGN AND We examined the gene expression prof
163 RESEARCH DESIGN AND We examined this question in skeleta
164 RESEARCH DESIGN AND We first quantified insulin sensitiv
165 ntal influences) were controlled for by this
research design and we further adjusted for time-varying
166 RESEARCH DESIGN AND We generated a T-cell receptor (TCR)
167 RESEARCH DESIGN AND We generated IL-21R-deficient NOD mi
168 RESEARCH DESIGN AND We generated TgKO mice expressing SH
169 RESEARCH DESIGN AND We generated transgenic mice overexp
170 RESEARCH DESIGN AND We genotyped approximately 360,000 s
171 RESEARCH DESIGN AND We genotyped single-nucleotide polym
172 RESEARCH DESIGN AND We initially demonstrated that the M
173 RESEARCH DESIGN AND We investigated the effect of nutrit
174 RESEARCH DESIGN AND We investigated the molecular mechan
175 RESEARCH DESIGN AND We investigated the relations of ser
176 RESEARCH DESIGN AND We measured GDR, fasting glucose, an
177 RESEARCH DESIGN AND We observed that activation of AMPK
178 RESEARCH DESIGN AND We performed a 60-h endotoxemia prot
179 RESEARCH DESIGN AND We performed cross-sectional analyse
180 RESEARCH DESIGN AND We show that glucose, acting through
181 RESEARCH DESIGN AND We studied mammary tumor development
182 RESEARCH DESIGN AND We studied the ability of cellular a
183 RESEARCH DESIGN AND We tested whether iNKT-conditioned D
184 RESEARCH DESIGN AND We tested whether these variants are
185 RESEARCH DESIGN AND We used bacterial artificial chromos
186 RESEARCH DESIGN AND We used ELISPOT to characterize the
187 RESEARCH DESIGN AND We used individual level genotype da
188 RESEARCH DESIGN AND We used mice and islets deficient in
189 RESEARCH DESIGN AND We utilized in vivo (13)C nuclear ma
190 RESEARCH DESIGN AND Wild-type and Nur77 null mice were f
191 RESEARCH DESIGN AND With two parallel approaches-a fat b
192 The
research designs and analytic methods used to address cl
193 ties Questionnaire, in relation to different
research designs and clinical purposes.
194 Whereas the sophistication of
research designs and data analysis for the study of psyc
195 sion-making and have used multiple different
research designs and data collection methods to explore
196 gical variation, one that may provide better
research designs and inform public policy.
197 ating older adults with cancer, (2) leverage
research designs and infrastructure for generating evide
198 eviews regarding the context, processes, and
research designs and interventions underlying CEnR that
199 l numbers of patients and the use of varying
research designs and methods have limited research in th
200 We next review the
research designs and results obtained from animal studie
201 We focus first on the variety of
research designs and substantive issues to which SEM can
202 There was marked heterogeneity in
research designs and the assessment of sedentary time an
203 a challenge to the predominant correlational
research designs and the search for sociodemographic or
204 ent for psychotherapeutic effectiveness, (b)
research design,
and (c) treatment technique.
205 mpirical study involves choosing a sample, a
research design,
and an analysis path.
206 (FDA) regulations do not adequately address
research design,
and that emergency research fits within
207 elated statistics, which are found in recent
research designs,
and the identified variants often over
208 ing partly because interventional controlled
research designs are difficult to apply.
209 Research designs are needed that enable longitudinal inv
210 , the most common problems found in proposed
research designs are related to unwarranted assumptions
211 the importance of the prospective nature of
research design,
as well as the consequences of its aban
212 on records rather than unique patients); (2)
research design (
avoiding use in performing state-, hosp
213 flexible yet robust statistical method, our
research design can be easily transferable to explore ur
214 ffectiveness of FSC certification because of
research design challenges, predominantly limited sample
215 mental health, which in turn have influenced
research-design changes in the field.
216 In implementing these prospective
research designs,
collaboration between researchers and
217 nd summarized according to key components of
research design concerning subject characteristics, ther
218 research results, and avoidable weakness in
research design,
conduct and analysis.
219 The natural experiment
research design controls for confounding variables, and
220 The co-twin control
research design controls for familial vulnerability and
221 problem, care orientation, conceptual bases,
research designs,
data analysis procedures, discussion o
222 In a previous article, the
research design,
details of the simulation protocol, and
223 In this article, the
research design,
details of the simulation protocol, inf
224 rends in future research including pragmatic
research design,
digital health interventions, and imple
225 oL research from 1990-2010 by discipline and
research design (
e.g., descriptive, longitudinal, clinic
226 These concordant findings using 2 different
research designs emphasize the importance of reducing SH
227 The authors examined which, if any,
research design features and patient characteristics wou
228 ay provide guidance in clinical practice and
research design for sequencing and prioritizing advanced
229 Prior
research designs,
however, have not leveraged the random
230 To inform
research design,
implementation and dissemination, this
231 periments by replicating and extending their
research design in a large-scale field experiment.
232 data also underlines the importance of sound
research design in benchmarking and comparison of bioinf
233 nd summarized according to key components of
research design,
including lesion type, location, and ad
234 By using explicit
research designs intended to isolate the causal effects
235 definition of self-care, use of theory, and
research design,
intended to provide guidance to researc
236 nce use in young people warrant high-quality
research design interventions to prevent or ameliorate t
237 y, specialists have suggested that the ideal
research design involving aDNA would include multiple in
238 ality of a study based solely on category of
research design is unscientific.
239 on included selection of area medical sites,
research design issues, comorbid conditions, alcohol abu
240 The most significant
research-design issues arose as a consequence of the lac
241 and data sharing in research through use of
research designs known to reduce inefficiencies, and fur
242 We conclude that recent advances in
research design may provide a transition that will bring
243 In particular, the focus is on issues of
research design,
measurements, mechanisms, potential eff
244 are reports, there was much heterogeneity in
research designs,
methods, study aims, and program targe
245 RESEARCH DESIGN/
METHODS AND RESULTS: Here, we identified
246 inical stroke is a desired goal, the current
research design of embolic protection devices focuses on
247 Despite decades of
research, design of new membrane materials remains a lar
248 protocol that raises ethical questions about
research design or implementation for which there is no
249 However, from a clinical-management and
research-design perspective, patient self-reports can be
250 s were included if they (a) used qualitative
research designs,
qualitative data collection and analys
251 ppeared in peer-reviewed journals; had clear
research designs;
reported results for at least 20 male
252 ust be put in the context of the appropriate
research design selection.
253 design and data analysis and suggest future
research design should consider including the 32 shared
254 ition research and community-based nutrition
research designs should be dictated by the local culture
255 Observational studies using traditional
research designs suggest that influenza vaccination redu
256 using a complement of genetically sensitive
research designs suggest that smoking during pregnancy i
257 The Task Force examines evidence of various
research designs that addresses the key questions within
258 f quantitative bias analysis and alternative
research designs that aim to decrease the strength of as
259 judgements could be a feature of evaluative
research designs that fail to accurately represent clini
260 Research designs that incorporate time have long been in
261 tions that produce eyeblink conditioning and
research designs that produce reinstatement in other for
262 y diverge from previous findings and propose
research designs that yield greater internal and externa
263 In the hierarchy of
research designs,
the results of randomized, controlled
264 What is the optimal
research design to address whether current and future ex
265 We used a quasi-experimental
research design to evaluate the association between coll
266 nt progress and well-developed strategies in
research designed to accomplish flexible and stretchable
267 This article reviews progress in
research designed to accomplish these outcomes with esta
268 Research designed to ameliorate neurodevelopmental disor
269 The PGC has recently commenced a program of
research designed to deliver "actionable" findings-genom
270 y in existing studies highlight the need for
research designed to examine the stability, comorbidity,
271 clude by outlining key priorities for future
research designed to facilitate precision management of
272 This article reports on
research designed to identify a core set of healing skil
273 ely to share etiology, so results may inform
research designed to identify causes.
274 Research designed to identify the etiology of these prob
275 ll ultimately provide support for innovative
research designed to increase the availability of organs
276 The present brief review describes
research designed to link these general concepts by exam
277 gestive carcinomas (ADCs), highlight ongoing
research designed to optimize their therapeutic effectiv
278 Basic
research designed to overcome these obstacles is current
279 the last 30 years, there has been extensive
research designed to quantify the extent of oral bioavai
280 history orientation conducted field and lab
research designed to reveal how animals cope with the ci
281 t risk-benefit ratios are molecular-targeted
research designed to target away from known adverse sign
282 fication of this relationship has stimulated
research designed to understand how HDL metabolism is re
283 ritique by employing a variety of innovative
research designs to identify the causal effect of father
284 Information was extracted on study location,
research design,
type of ICU, healthcare workers, measur
285 The
research design used geomorphological and palynological
286 l is a panacea to rectify limitations of the
research design used to gather data.
287 hnologies for Advanced Genomics Analysis and
Research Design (
VANGARD), has developed a thorough exom
288 A mixed-methods
research design was applied.
289 therapy interventions; the most common study
research design was before-after studies (33%).
290 ohort study using a difference-in-difference
research design was conducted from March 14, 2020, to Ap
291 ignored the fact that Brosnan and de Waal's
research design was not capable of offering an unequivoc
292 A quasi-experimental
research design was used, and the study followed the tra
293 IGN, SETTING AND PARTICIPANTS: A qualitative
research design was used.
294 g 3 studies using distinct but complementary
research designs were used: The Christchurch Health and
295 alternative to previously used epidemiologic
research designs when one is including localization in t
296 dy highlights the power of transdisciplinary
research designs when using aDNA data and sets a methodo
297 f the hospitalist model requires an adequate
research design,
which should include a precise definiti
298 so used cross-sectional and/or retrospective
research designs,
which led to researchers and clinician
299 cepted principles of scientific inquiry, the
research design will generate an appropriately phrased h
300 A cross-sectional
research design with chain mediation model involving 461