ライフサイエンスコーパス: resection

1 heatre, and 26 (87%) underwent successful R0 resection.

2 er tissues of 3 patients who underwent liver resection.

3 owed by APE2 recruitment to continue SSB end resection.

4 to DNA break sites and inhibition of DNA end resection.

5 s without evidence of disease >5 years after resection.

6 surgical complication rate after pancreatic resection.

7 dies on standardized surveillance after PDAC resection.

8 mately 50% of patients died within a year of resection.

9 irrhosis or normal liver tissue from hepatic resection.

10 umulate due to defective MRE11 initiation of resection.

11 ications or mortality in patients undergoing resection.

12 patient samples obtained from transurethral resection.

13 ociated with higher predicted rates of colon resection.

14 ents, 3-10 weeks and 1 year after ileocaecal resection.

15 stence could explain incomplete responses to resection.

16 ven as neoadjuvant treatment before surgical resection.

17 e of HCC at 22 and 26 months following liver resection.

18 to detect residual tumor tissue after glioma resection.

19 triple negative breast tumors after surgical resection.

20 cycles, which were then followed by surgical resection.

21 de yields (LNY) compared to initial surgical resection.

22 idity and/or are not candidates for pancreas resection.

23 not be reversed by suppressing excessive end resection.

24 the survival of the treated mice post tumor resection.

25 herapy improves overall survival after liver resection.

26 eceiving first-line chemotherapy followed by resection.

27 ransplanted on the affected eye after pannus resection.

28 y SBRT and 475 (45%) underwent delayed wedge resection.

29 status in risk of recurrence after surgical resection.

30 and annealing repair involving extensive end resection.

31 icrobiome, in mice that underwent colorectal resection.

32 hymal margin) with recurrence after surgical resection.

33 colon polypoid lesions), ablation, piecemeal resection.

34 tor for colorectal recurrence after curative resection.

35 val of patients with HCC treated by surgical resection.

36 oing transthoracic or transhiatal esophageal resections.

37 detrimental outcome despite successful tumor resections.

38 ostoperative complications after major liver resections.

39 tal (46.4%) gastrectomy were the predominant resections.

40 , radiologically solid nodules, and anatomic resections.

41 121 multivisceral resections and 171 venous resections.

42 -organ metastasis to the lung compared to no resection (14.0 +/- 1.93 months vs 6.0 +/- 0.31 months,

43 %; PTx and hemithyroidectomy: 24.1%; en bloc resection 15.7%; others 37.3%] and complications of surg

44 ) pancreaticoduodenectomy, 40,328 (14%) lung resection, 16,127 (6%) CABG and 10,602 (3%) esophagectom

45 ed including all patients who underwent PDAC resection (2014-2016).

46 Of the 77, 73 (95%) underwent successful resection; 21 (29%) required vascular reconstruction, 62

47 04) and anatomic resection compared to wedge resection (88.2% vs 52.2%, P = 0.04).

48 at of patients who underwent "delayed" wedge resection (90-120 days after diagnosis).

49 arly HCC who are not candidates for surgical resection, ablation and liver transplantation should be

50 hepatobiliary malignancies include surgical resection, ablation, and liver transplantation.

51 The study describes the risk factors for R1 resection after liver surgery for CRLMs, which may be us

52 acquired over several decades and series of resection after patient selection by neoadjuvant therapy

53 om 16 centers, of whom 66 patients underwent resection after preoperative therapy and 98 patients aft

54 be improved in patients undergoing surgical resection, although this difference did not meet the MID

55 For patients with incomplete surgical resection, an additional boost of 14.4 Gy was delivered

56 significantly increased survival compared to resection and ablation, the absolute incremental surviva

57 romotes initiation of HR by facilitating end-resection and accumulation of CtIP at IR-induced foci.

58 consistent in patients treated with upfront resection and adjuvant chemotherapy (DM 83.0%, LR 16.9%)

59 ent for glioblastoma (GBM) includes surgical resection and adjuvant radiotherapy (RT) and chemotherap

60 a stretched scar, which must be treated with resection and advancement of the medial rectus.

61 ated MRX and cohesin loading, despite normal resection and checkpoint activation.

62 The current standard of care-resection and chemoradiation-is limited in part due to t

63 valuated visually for complete or incomplete resection and compared with MRI.

64 R0 resection and complete mesocolic excision rate were 94%

65 lly impaired at DNA breaks, with reduced end resection and diminished recruitment of downstream repai

66 ic endoscopic interventions (eg, endoluminal resection and endoscopic sphincterotomy) and be familiar

67 29) or after (n = 56) anterior temporal lobe resection and healthy volunteers (n = 124) comparable re

68 mpass both benign tumors cured with surgical resection and highly lethal cancers with no efficacious

69 vo hepatectomy (n = 18), followed by ex vivo resection and intestinal autotransplantation (n = 12), e

70 went hepatectomy for CRLM, 1497 had complete resection and known BRAF status.

71 m Hg; P=0.67) mitral gradients after leaflet resection and leaflet preservation, respectively.

72 The rates of R0 resection and pathologic invasion of venous and arterial

73 Equipoise exists between the use of leaflet resection and preservation for surgical repair of mitral

74 BRCA1 promotes the DNA end resection and RAD51 loading steps of homologous recombin

75 rates for patients in A3973 with incomplete resection and radiotherapy (n = 47) were 10.6% +/- 4.6%,

76 Our in vivo studies with a resection and recurrence mouse model suggest that this p

77 clinically relevant orthotopic models of GBM resection and recurrence.

78 Here we introduce a resection and response-assessment approach for studying

79 lso prevents tumor recurrence after surgical resection and results in 100% metastasis-free survival u

80 val analysis of patients who underwent tumor resection and started adjuvant chemotherapy showed impro

81 cents who have undergone unilateral cortical resection and, yet, display remarkably normal behavior.

82 eatment options include brachytherapy, local resection and/or cryotherapy in selected cases.

83 larger than 20 mm, and endoscopic submucosal resection and/or dissection as polypectomy approaches.

84 mor recurrences, including 121 multivisceral resections and 171 venous resections.

85 Colorectal resections and anastomoses were then performed.

86 f distal switch regions (consistent with end resection), and preferential usage of microhomology-all

87 Four patients underwent liver resection, and 1 was treated with radioembolization.

88 8 (26.7%) received LT, 244 (11.5%) underwent resection, and 1317 (61.59%) received ablation.

89 Ninety-one percent patients had R0 resection, and 57% had no recurrence to date with median

90 , monitor treatment response, focus surgical resection, and enable image-guided biopsy.

91 ain an oncological benefit with this type of resection, and many problems must still be solved.

92 chemotherapy, 105 (89%) simultaneous venous resections, and 101 (85.5%) arterial reconstructions.

93 Evidence for any dysplasia, colon segment resection, aneuploidy, male sex, and age was classified

94 ue Myectomy (IOM), Inferior Oblique combined Resection-Anterior Transposition (IORAT) and Inferior Ob

95 e roles of these proteins in nucleolytic DSB resection are well characterized, but their role in brid

96 Hepatic resections are associated with a significant acute syste

97 ompletion of neoadjuvant therapies and tumor resection as well as to cancer survivors could eliminate

98 underwent esophageal, pancreatic, or rectal resections at far HVH meeting volume standards versus lo

99 established injury model of ventricular apex resection, autophagy plays a critical role during cardia

100 et minimum volume thresholds for lung cancer resection based on definitions provided by the Volume Pl

101 eria for high-dose therapy (HDT), and had no resection before induction were included.

102 uded patients with HCC treated with surgical resection between January 2008 and February 2018 and who

103 ibonucleotides at the 5' terminus stimulates resection by EXO1.

104 urs at gaps formed by PrimPol re-priming and resection by MRE11 and EXO1.

105 ortality and morbidity for colorectal cancer resections by Lapco delegates and non-Lapco surgeons in

106 nopathy were technically resectable but that resection carried a substantial risk of morbidity becaus

107 This process is initiated by a short-range resection catalyzed by MRE11-RAD50-NBS1 (MRN) stimulated

108 ES) for insertion into the margin of the GBM resection cavity to provide a sustained high local dose

109 hanges in (18)F-FET uptake at the rim of the resection cavity within the first 2 wk after resection o

110 d by maximum lesion-to-brain ratios near the resection cavity.

111 ules (77.4% vs 33.3%, P = 0.04) and anatomic resection compared to wedge resection (88.2% vs 52.2%, P

112 tumors, allowing IGS and more complete tumor resection compared with white light surgery.

113 In patients with PMNSGCT undergoing resection, completeness of resection, postoperative path

114 Individuals who underwent colon resection, coronary artery bypass graft (CABG), lung res

115 Exonucleolytic resection, critical to repair double-strand breaks (DSBs

116 vascular bypass, lung resection, pancreatic resection, cystectomy, or esophagectomy.

117 Upfront resection decreased over time and 15.4% of patients even

118 Our data might help explain the less severe resection defects of MRE11 nuclease-deficient cells comp

119 5% of patients remain ineligible for hepatic resection due to insufficient hypertrophy of the FLR.

120 ilure to cure was defined as: 1) no surgical resection due to intraoperative metastasis or locally ir

121 Local control consisted of surgical resection during induction chemotherapy and radiotherapy

122 ive strategies to reduce the incidence of R1 resection during OLS and LLS.

123 Endoscopic mucosal resection (EMR) is a minimally invasive procedure used f

124 dy was to evaluate the outcome of endoscopic resection (ER) versus esophagectomy in node-negative cT1

125 -day cycle, for three cycles before surgical resection, followed by adjuvant intravenous nivolumab mo

126 rst sensed by APE1 to initiate 3'-5' SSB end resection, followed by APE2 recruitment to continue SSB

127 pancreas, esophageal, lung, rectal, or colon resection for cancer at a hospital within the highest-qu

128 cologic efficacy of laparoscopic versus open resection for CLM.

129 Ex vivo surgery may provide a chance at R0 resection for conventionally unresectable tumors.

130 ation and may be the main drivers of colonic resection for diverticular disease.

131 edicare patients underwent an elective colon resection for diverticulitis at 2462 hospitals over the

132 Patients undergoing liver resection for HCC between 2008 and 2018 in 18 Centers en

133 follow-up data on recurrence after surgical resection for IPMN are currently lacking.

134 In order to improve the efficacy of resection for lesions >=2 cm and to optimize R0 resectio

135 Further, studies on resection for metastatic disease to the lung were system

136 orty-four patients undergoing elective colon resection for nonmetastasized cancer were randomly assig

137 ns of first recurrence after curative-intent resection for pancreatic adenocarcinoma (PDAC).

138 tive cohort study of 233 patients undergoing resection for rectal cancer from January 2007-October 20

139 adult patients undergoing elective abdominal resection for rectal cancer over a 10-year period were r

140 All patients undergoing upfront resection for resectable and borderline-resectable PDAC

141 rfusion injury (IRI) during liver-metastasis resection for treatment of colon cancer may increase the

142 Overall, 3387 consecutive liver resections for CRLMs were included.

143 sessing tumor regression in post-neoadjuvant resections for PDAC.

144 ectomies, 79 distal pancreatectomies, and 10 resections for tumor recurrences, including 121 multivis

145 on was observed in 3 subjects in the leaflet resection group and 2 in the leaflet preservation group.

146 Gross total resection (GTR) was achieved in 119 cases (70.8%) with t

147 However, the CC resection had no significant effects on the distribution

148 ceiving second-line chemotherapy followed by resection had significantly worse OS and PFS than patien

149 the indications for and complexity of liver resections have evolved.

150 multivariable models, patients who underwent resection (hazard ratio: 5.42; 95% confidence interval:

151 d high-grade dysplasia (HGD) in the original resection (HR 3.60, 95%CI 1.13-11.48; P = 0.03) were ass

152 nsarterial chemoembolization (TACE), hepatic resection (HR) and chemotherapy (CTX).

153 72 patients (77%) and incomplete macroscopic resection (IME) in 359 (23%).

154 sis of (18)F-FET PET scans revealed complete resection in 16 of 43 patients and incomplete resection

155 The clinical impact of R1 resection in liver surgery for CRLMs has been continuous

156 The model was able to predict R1 resection in OLS (area under curve 0.712; 95% confidence

157 nsplantation should be probably preferred to resection in regard of organ availability.

158 esection in 16 of 43 patients and incomplete resection in the remaining patients.

159 performed 25 years ago as an alternative to resection in the treatment of extensive fibrostenosing j

160 perform fluorescence-guided surgical tumour resection, in mice.

161 Surgeon-assessed extent of resection included complete macroscopic excision (CME) i

162 s short-term benefits compared to open liver resection, including decreased blood loss and postoperat

163 d-joining contributing to the robustness and resection independence of A-EJ-mediated CSR.

164 Similarly, surgical resection is also the definitive treatment for biliary t

165 unction in lung cancer patients before tumor resection is essential for patient selection for surgery

166 a comparison between ESD and local surgical resection is needed to guide decision making for the opt

167 Partial organ resection is not only a common clinical approach in canc

168 le for a stage to be assigned until surgical resection is performed.

169 n and opioid use in patients undergoing lung resection is unknown.

170 repair, in that repair is initiated with end resection, leading to single-stranded 3' ends, which req

171 Although laparoscopic liver resection (LLR) was initially indicated for small benign

172 eration, readmission, oncologic outcomes (R0-resection, lymph nodes harvested), and operative times.

173 ling was assessed by gastroscopy, histology (resection margin [R] positivity of polypectomy or biopsy

174 A microscopically clear resection margin is most important in predicting overall

175 a transition zone and proximal pull-through resection margin where ENS was present.

176 samples of the oral tumour and the surgical resection margin with more than 95% sensitivity and spec

177 sion, perineural invasion, T-stage, N-stage, resection margin, and adjuvant chemotherapy were correla

178 pecimen's surface to detect PC tissue at the resection margin.

179 , in up to 18.6% of patients, tumor-positive resection margins are detected on histopathology.

180 patients with R0 versus R1 margins but wider resection margins do not confer a survival benefit [57 m

181 erall POM, intraoperative complications, and resection margins, was performed.

182 from 27 to 70 days in a GBM xenograft mouse resection model with no sign of tumour recurrence.

183 care beneficiaries undergoing an elective HP resection, more than 1 in 4 hospitals performing HP surg

184 Surgery (hepatic artery ligation n = 26; resection n = 13; embolization n = 1) was required in 40

185 Laparoscopic liver resections necessitate a long learning curve trough a st

186 xplain why eukaryotic cells possess multiple resection nucleases.

187 carcinoma can occur years after the surgical resection of a non-invasive IPMN.

188 Complete surgical resection of abnormal brain tissue is the most important

189 ove predicting survival and recurrence after resection of ampullary adenocarcinoma.

190 It requires resection of broken ends to generate long, 3' single-str

191 rognosis for patients who undergo concurrent resection of CLM/EHD is unclear and the impact of somati

192 Adjuvant HAI after resection of CRLM is independently associated with impro

193 The nucleolytic resection of DSB-adjacent DNA is a key step in meiotic D

194 resection cavity within the first 2 wk after resection of gliomas.

195 the MRE11 nuclease that is implicated in the resection of HU-induced stalled replication forks.

196 and safety of TAMIS and ESD for the en bloc resection of large non-pedunculated rectal lesions.

197 En-bloc resection of large, flat dysplastic mucosal lesions of t

198 d to completely describe surgical biopsy and resection of NBL and their outcomes.

199 rols; P = .1) or proportion of subjects with resection of non-neoplastic lesions (26.0% in the CADe g

200 antage over chemotherapy alone after upfront resection of PDAC.

201 Outcomes after resection of PMNSGCTs are not well-characterized, with l

202 egative margins are the goal of any surgical resection of primary oral cavity carcinoma.

203 of the premetastatic microenvironment after resection of primary tumours.

204 ing tumor tissues are needed during surgical resection of prostate adenocarcinoma.

205 56 genome, cloning of several fragments, and resection of the fragments that retained the exclusion p

206 s a rare disease that results from extensive resection of the intestine.

207 2 months and 83.0 +/- 24.84 months following resection of the primary tumor and metastasis, respectiv

208 The role of early resection of the primary tumor in metastatic small bowel

209 Complete surgical resection of the primary tumor is an important part of N

210 st lesion>5.5 cm, and less than 2 years from resection of the primary tumor to transplantation.

211 Resection of the primary tumor was associated with longe

212 However, there is mounting evidence that resection of the primary tumour and/or localised radioth

213 While recession-resection of the vertical recti and weakening of both el

214 ere collected for 546 patients who underwent resection of their PDAC between 2005 and 2016 from 2 ter

215 On this basis, fluorescence-guided resection of tumor masses was successfully carried out o

216 ents with VHL disease who underwent surgical resection of tumors between November 2014 and October 20

217 Surgical resection of tumours requires precisely locating and def

218 ome available for minimally invasive en bloc resections of large non-pedunculated rectal lesions (pol

219 radiotherapy, phototherapy and local tumour resection, often administered in combination.

220 1 or APE1 leads to greater dependence of DNA resection on DNA2.

221 d effectively delineates tumors for improved resection on the day after administration.

222 the incremental survival benefit of LT over resection or ablation was small, between 0.02 and 0.03 y

223 ich is costly and only available after tumor resection or biopsy.

224 epair of mitral prolapse with either leaflet resection or leaflet preservation was associated with si

225 tation surgically amenable to either leaflet resection or preservation were randomized at 7 specializ

226 ive decision making with regard to extending resections or applying intraoperative radiation therapy

227 acroscopically or microscopically incomplete resection, or 3) 30-day/in-hospital mortality.

228 graft (CABG), pancreaticoduodenectomy, lung resection, or esophagectomy from 2006-2017.

229 n, coronary artery bypass graft (CABG), lung resection, or lower extremity joint replacement (LEJR) w

230 We performed a partial resection, or partial sialoadenectomy, in the female mur

231 uding age, tumor location, M stage, surgical resection, order of therapy, germline status, and molecu

232 ntracranial EEG (iEEG) findings and surgical resection outcomes in a cohort of 36 patients with focal

233 xygen, neonatal ventilator use, and neonatal resection (p < 0.001).

234 rgest cohort of pancreatectomy with arterial resection (P-AR).

235 epair, lower extremity vascular bypass, lung resection, pancreatic resection, cystectomy, or esophage

236 MNSGCT undergoing resection, completeness of resection, postoperative pathology, and postoperative ST

237 b and provides advantage in PFS, ORR, and R0 resection rate at the price of a moderate increase in to

238 ve chemoradiotherapy may improve the radical resection rate for resectable or borderline resectable p

239 ed in 1792 cases whereas LLS in 1595; the R1 resection rate was 14% and 14.2%, respectively.

240 The resection rate was 61% and 72% (P = .058).

241 R0 resection rate was similar between the groups.

242 In terms of the outcomes survival, resection rate, and R0 resection rate, this appeared to

243 Measured parameters included resection rate, margin positivity, pathologic response,

244 he outcomes survival, resection rate, and R0 resection rate, this appeared to be a representative gro

245 , and compared resection rates, radical (R0) resection rates and overall survival (OS) between the va

246 ection for lesions >=2 cm and to optimize R0 resection rates of lesions suspected of harboring high-g

247 not participating in the trial, and compared resection rates, radical (R0) resection rates and overal

248 ion (excess of 3-fold) in standardized colon resection ratios for recurrent diverticulitis.

249 Standardized colon resection ratios ranged from 0 in the Tuscaloosa HRR to

250 's disease (CD) who have undergone ileocecal resection remains to be established.

251 Surgical resection resulted in a significant 36.2% reduction in m

252 inal adaptation occurs weeks to months after resection, resulting in hyperplasia of the remnant gut,

253 protein 1 (53BP1)-associated complex in DNA resection sheds light on how BRCA1 influences the choice

254 BEST PRACTICE ADVICE 11: Surgical resection should be performed at high-volume centers.

255 An elective segmental resection should not be advised based on the number of e

256 surgery to RT, in conjunction with extent of resection, should be considered in the clinical manageme

257 ve a pathologically complete response in the resection specimen.

258 e-guided imaging (FGI) of the fresh surgical resection specimens (n = 8) was performed.

259 A total of 328 transurethral resection specimens from 232 patients were included, and

260 We evaluated resection specimens with marked target fields from 151 c

261 of 'difficult-to-replicate' DNA regions, end resection, stalled replication fork processing, and mito

262 activity of DNA2 involved in the long-range resection step.

263 y 1 case with an orbital pseudotumor was the resection subtotal because of the fibrous consistency, i

264 st assessed the risk for aerosol during lung resection surgery and proposed steps for mitigation.

265 guidelines for the conduct of elective lung resection surgery in this context.

266 In the context of lung resection surgery, specific time points during the proce

267 efaecatory dysfunction known as Low anterior resection syndrome (LARS).

268 function complaints, namely the low anterior resection syndrome (LARS).

269 ents each who received early SBRT or delayed resection that were well-matched with regard to baseline

270 s of ICL repair to prevent aberrant nuclease resection, the role of BRCA2 in this process has not bee

271 ation positive because both require surgical resection, the sensitivity increased to 97.5% and the PP

272 Root resection therapy remains a treatment solution for molar

273 th remained functional after 9 years of root resection therapy.

274 recurrent disease after previous small bowel resection, thickened mesentery, large inflammatory mass,

275 (S25A) allows sufficient DNA2-dependent end resection to rescue the lethality of BRCA1(Delta11) mice

276 Sensitivity analysis excluding emergent resections to define USBR did not alter the results.

277 Resection tracts averaged 1100 nt, but with substantial

278 e examined the impact of upfront small bowel resection (USBR) for metastatic SB-NET compared to non-o

279 ate the direct detection of meiotic DSBs and resection using END-seq on mouse spermatocytes with low

280 nce was 451+/-147 m for those in the leaflet resection versus 481+/-95 m for the leaflet preservation

281 rt the hypothesis that a strategy of leaflet resection (versus preservation) is associated with a ris

282 The predictive size of tumor for R1 resection was >45 mm in OLS and >30 mm in LLS, > 2 lesio

283 /- 1.1 mm, and the mean medial rectus muscle resection was 6.7 +/- 0.9 mm.

284 A gross total resection was achieved in 95.5% of patients.

285 Laparoscopic resection was associated with a lower hazard rate of dea

286 In multivariable analysis, delayed resection was associated with improved survival [adjuste

287 Surgical resection was performed in 85% and radiation in 55%.

288 hroplasty, total knee arthroplasty, and lung resection were identified.

289 Associated strictureplasties and bowel resection were performed in 44% and 80%, respectively.

290 4-28.1) and 35 of 41 patients who had tumour resection were progression free.

291 f 151 patients who underwent a major hepatic resection were randomized (mean age = 62.8 years; 57% ma

292 After DS, more laparoscopic resections were performed (56.8% vs 9.2%, P < 0.001) and

293 ese ALT-EJ events likely require limited end resection, whereas RNF8 is not required for single-stran

294 tients undergoing a colectomy, CABG, or lung resection who lived in highly socially vulnerable counti

295 uence reported in the present study in colon resections with primary anastomosis.

296 oradiation (median dose 50.4 Gy) followed by resection within 4 months.

297 USBR was defined as resection within 6 months of diagnosis.

298 Elective Sigmoid Resection within 6 weeks vs. Conservative Management MAI

299 cohort study of patients undergoing anterior resection within the ROLARR trial was undertaken.

300 emic therapy and undergo successful surgical resection without prohibitive perioperative complication