ライフサイエンスコーパス: reservoir

1 ats into people, possibly in an intermediate reservoir.

2 sought to reduce the size of the latent HIV reservoir.

3 n through Earth's largest terrestrial carbon reservoir.

4 me sequences of CCHFV directly from the tick reservoir.

5 d multilayered surface-associated surfactant reservoir.

6 in the host rock surrounding the Axial magma reservoir.

7 dendritic cell immunotherapeutic, on the HIV reservoir.

8 h uses microfluidic devices to mimic the oil reservoir.

9 patient-to-patient transmission or a common reservoir.

10 My of change in the ocean's largest oxidant reservoir.

11 ence and reduce the size of the latent viral reservoir.

12 proaches aimed at eliminating the latent HIV reservoir.

13 r response and expansion of the viral latent reservoir.

14 2019 from a currently uncharacterised animal reservoir.

15 SARS-CoV-2), emerged, likely from a zoonotic reservoir.

16 at (ERB; Rousettus aegyptiacus) as a natural reservoir.

17 ex, called the surface-associated surfactant reservoir.

18 id electrolyte separates the channel and the reservoir.

19 cs mechanisms for the possible deep-Earth Xe reservoir.

20 of the pneumococcus for sustaining its human reservoir.

21 .06-2.54 log(10) reduction in the HIV latent reservoir.

22 bovines have been identified as its natural reservoir.

23 cle) and share an arteriovenous fluid-mixing reservoir.

24 id, and humans are the organism's only known reservoir.

25 ontrols the size of the permissive host cell reservoir.

26 ART plus kick and kill on markers of the HIV reservoir.

27 ceramic disk was elevated over 3 m above the reservoir.

28 center response and expansion of the latent reservoir.

29 y other lipophilic ARVs for treatment of HIV reservoir.

30 is known about the biology of NiV in the bat reservoir.

31 increase in the delta(34)S of Earth surface reservoirs.

32 man and animal pathogens persist in wildlife reservoirs.

33 s an insufficient depiction of the risks and reservoirs.

34 microbial communities resident in heavy oil reservoirs.

35 ld potentially expand and sustain HIV tissue reservoirs.

36 y occur at present in critically pressurized reservoirs.

37 eractions with surface-laden condensed-phase reservoirs.

38 ing the risks of CO(2) storage in geological reservoirs.

39 model to study the impact of opioids on HIV reservoirs.

40 rebound, mostly due to the presence of viral reservoirs.

41 te formulation for application to soured oil reservoirs.

42 be key human immunodeficiency virus (HIV)-1 reservoirs.

43 infection and treatment-resistant bacterial reservoirs.

44 estock, and wildlife that could act as viral reservoirs.

45 s occur at conditions pertinent to petroleum reservoirs.

46 and pangolin were proposed to be the natural reservoirs.

47 Patients with diabetes had impaired LA reservoir (19.8% vs. 21.2%, P < 0.01) and conduit (7.6%

48 opia by simulating the filling period of the reservoir; a new normal period after the reservoir fills

49 unctional and non-genetically evolving viral reservoir along with an HIV-1-specific immune response s

50 n comparison with STE derived strain, the RA reservoir and conduit strain were not significantly diff

51 TnT functions as a myofilament Ca(2+) buffer/reservoir and is potentially critical to the high-freque

52 pacity of LDL to act as a plasma cholesterol reservoir and its potential impact in supporting the m-R

53 ctors determining disparate outcomes between reservoir and spillover hosts and defensive strategies l

54 ce of the virus was spillover from an animal reservoir and subsequent adaptation to humans sometime d

55 The focus of this report is HIV-1 reservoirs and correlates in the peripheral blood of chi

56 We introduce important reservoirs and processes affecting N in the environment,

57 environments; VBNC cells serve as important reservoirs and still pose threats to public health.

58 Finger-operated reservoirs and valves capable of fully-reversible dispen

59 e unable to eliminate the FDC-associated HIV reservoir, and alternative strategies to eradicate this

60 bundant at the villus base and provide a BMP reservoir, and we identified a CD81(+) PDGFRA(lo) popula

61 zation, viral evolution, generation of viral reservoirs, and compartmentalization are still a matter

62 ce of naphthalene-derived metabolites in oil reservoirs, and provides a simple experimental tool for

63 An infected reservoir animal host is often required for maintenance

64 emoval of dams on rivers and their connected reservoirs applies predominantly to smaller structures (

65 s that enable sanctuary specifically in this reservoir are unclear.

66 While prior studies have shown that aquatic reservoirs are important in the persistence of the disea

67 c data reflect sustained transmission within reservoir areas, further expanded by periodic importatio

68 questration, CO(2) is injected into geologic reservoirs as a supercritical fluid (scCO(2)).

69 o enhance immune recognition of latent viral reservoirs as part of a strategy for HIV clearance.

70 ust evidence of the establishment of aquatic reservoirs as well as ongoing evolution of V. cholerae i

71 early detection and treatment of infectious reservoirs, as well as the in vivo analysis of factors t

72 es from 50 ART-suppressed individuals in the Reservoir Assay Validation and Evaluation Network (RAVEN

73 the size of the deep-water marine phosphorus reservoir, associated with rising sulfate concentrations

74 an immunological mechanism by which the bat reservoir asymptomatically hosts MARV.

75 g water, already occurred in the clean water reservoir at the treatment plant before further distribu

76 maintained in individuals or populations of reservoir bats remain an enigma.

77 nt than the central faculae because the deep reservoir brines took a longer path to the surface and c

78 fected children limits the size of the virus reservoir, but whether the time of treatment initiation

79 may contribute to the longevity of the HIV-1 reservoir by stimulating the clonal expansion of latentl

80 V-coinfected persons, may sustain HIV tissue reservoirs by promoting T-cell proliferation but are poo

81 Both polymeric film and lyophilised reservoirs candidate patches achieved esketamine plasma

82 lyophilised reservoirs were assessed as drug reservoir candidates.

83 suggests that the brain can be an important reservoir causing long-term viral persistence.

84 all individuals, account for the majority of reservoir cells and are often maintained over time on AR

85 d to uninfected cells, the TCR repertoire of reservoir cells is heavily biased: expanded clonotypes a

86 ors that control HIV multiplication in these reservoir cells.

87 al levels of integrated virus, the degree of reservoir clearance was still insufficient to achieve vi

88 ransport through and transformation within a reservoir complex.

89 However, reservoir composition differs between tissues and blood,

90 Our findings highlight unique features of reservoir composition in pediatric infection that should

91 Here, we demonstrate a memristor-based reservoir computing (RC) system that can potentially ana

92 of mutual isotopic equilibrium (generally at reservoir conditions), suggesting that they form a secon

93 e evaluated using site-specific crude oil at reservoir conditions.

94 ) and circumferential and radial strains; LA reservoir, conduit, and booster pump strains; and infarc

95 In this study, impact of reservoir confinement (stress) on porosity and permeabil

96 ained in one fluidic compartment to a second reservoir, containing the enzyme CRE deiminase.

97 After 6 Ma, however, continental carbon reservoirs contract rather than expand during cold perio

98 lysis illustrates how during filling the HAD reservoir could fall to levels not seen in recent decade

99 lly modified magnesium silicates (MSils)-for reservoir drilling fluids where organic functionalities

100 ld contribute to the dynamics of the HIV DNA reservoir during suppressive ART, even when ART is initi

101 uch as herpesviruses, may sustain HIV tissue reservoirs during suppressive ART, suggesting future cur

102 However, the effect of opioids on viral reservoir dynamics remain elusive.

103 PW from oil reservoirs (e.g., Permian) is ~15x higher than that from

104 ured organisms from oil-contaminated and oil reservoir ecosystems.

105 oring the availability of the electron pair (reservoir emptying).

106 Via reservoir engineering and analogue quantum simulation te

107 application of microneedle patches with drug reservoir F3 and LW3, were 0.260 mug/ml and 0.498 mug/ml

108 nt toward the existence of an extra-European reservoir feeding plague into Western Europe in multiple

109 the reservoir; a new normal period after the reservoir fills; and a severe multi-year drought after t

110 a novel approach to characterizing the HIV-1 reservoir, focusing on the genetic integrity of individu

111 Human asymptomatic carriage as a reservoir for community transmission of infections might

112 in crop wild relatives can provide a genetic reservoir for crop improvement.

113 ell reprogramming into T(SCM) that acts as a reservoir for effector T cells with potent therapeutic c

114 human pharynx is commonplace and a potential reservoir for GAS transmission.

115 We propose that the aECM presents a rich reservoir for generating morphological novelty and highl

116 The atmosphere is a significant global reservoir for mercury (Hg) and its isotopic characteriza

117 or bacterial survival and establishment of a reservoir for outbreaks of high-level antibiotic resista

118 tic niche of the bone marrow (BM) is a major reservoir for parasite replication and the development o

119 Hotspots constitute the major reservoir for residual malaria transmission, with higher

120 Public aquaria will serve not only as a reservoir for the purpose of conservation, restoration,

121 ritidis (SE) in the chicken host serves as a reservoir for transmission of Salmonella to humans throu

122 Thus, European swine populations represent reservoirs for emerging IAV strains with zoonotic and, p

123 S-Nitrosothiols (RSNOs) serve as air-stable reservoirs for nitric oxide in biology.

124 lls, producers of pathogenic antibodies, and reservoirs for viruses that trigger demyelination.

125 ions; monitoring the mechanical integrity of reservoir formations is essential for effective and safe

126 The reservoir-free Al@Al half-cell is stable at 1000 cycles

127 Differences in HIV reservoir frequency and immune activation appear to be s

128 Aquatic birds represent a vast reservoir from which new pandemic influenza A viruses ca

129 from the aqueous environment and serve as a reservoir from which Wnt proteins can be handed over to

130 xtent to which interaction between hosts and reservoirs generates new infections.

131 suggests a role for intrinsic resistance of reservoir-harboring cells to CTL killing.

132 otyped directly, the features of the in vivo reservoir have remained elusive.

133 silicate Earth (BSE), and all its sampleable reservoirs, have a subchondritic niobium-to-tantalum rat

134 ICP was manipulated by varying reservoir height, and eye outflow facility (C) was deter

135 y combinations effective at targeting latent reservoir HIV-1 viruses from 10 individuals.

136 appealing solution to managing rabies in its reservoir host.

137 ces in the life history features of zoonotic reservoir hosts into pathogen transmission models, enabl

138 of the dynamics of these pathogens in their reservoir hosts is crucial to inform the risk of spill-o

139 ships, consisting of the avian and mammalian reservoir hosts of 415 RNA and DNA viruses along with th

140 leptospires that are excreted via urine from reservoir hosts of infection.

141 Thus, the P. falciparum reservoir in all ages can contribute to the maintenance

142 ct proviral DNA levels, and in inducible SIV reservoir in lymph nodes (LNs) of morphine administered

143 However, HIV-1 persists in a latent reservoir in resting CD4(+) T cells, and rebound viremia

144 h most infections occurring near the natural reservoir in rural areas and in individuals more likely

145 not sediment, is the primary carbon-bearing reservoir in slabs subducted to deep-lithospheric and tr

146 d the impact of hemoglobin, the largest iron reservoir in the body, on pneumococcal physiology.

147 hey often fail to effectively tackle the HIV reservoir in the brain because of inefficient penetratio

148 for neuronal access to an astrocytic energy reservoir in the hippocampus and neocortex, compromising

149 both HIV-infected CD4(+) T cells and the FDC reservoir in vitro Although CAR-T cells eliminated CD4(+

150 -affinity binding sites act as a competitive reservoir in vivo from which transcription factors are r

151 nic compounds (SVOCs) partition among indoor reservoirs in (1) a manufactured test house under contro

152 CE To cure HIV, we likely need to target the reservoirs in all anatomic compartments.

153 people with HIV who abuse opioids had higher reservoirs in CNS than the lymphoid system.

154 esearch, but the characteristics of proviral reservoirs in elite controllers remain to be determined.

155 ance of characterizing antibiotic resistance reservoirs in hospitals and establish the feasibility of

156 agent (LRA) to date effectively clears viral reservoirs in humans, suggesting a need for new LRAs and

157 esulted in efficient targeting of LPV to HIV reservoirs in mesenteric lymph and MLNs.

158 erapeutic strategies to reduce/eliminate HIV reservoirs in opioid dependent PLWH.IMPORTANCE Identific

159 show that methane emissions from old carbon reservoirs in response to deglacial warming were small (

160 y and potential to traffic to sites of viral reservoirs in SIV-infected rhesus macaques had no demons

161 HIV-1 reservoirs in the central nervous system (CNS) are chall

162 promising step toward the elimination of HIV reservoirs in the clinic.

163 d perivascular macrophages are important HIV reservoirs in the CNS.

164 (perivascular macrophages) are important HIV reservoirs in vivo, especially in the central nervous sy

165 ed blood cells and tissues known to be viral reservoirs including lymph nodes, spleen, bone marrow, a

166 Reservoirs interfaced with the chip use hydrostatic pres

167 trategy to reduce the size of the latent HIV reservoir is an avenue that should be explored.IMPORTANC

168 e primary human immunodeficiency virus (HIV) reservoir is composed of resting memory CD4(+) T cells,

169 om that of adults, which may alter where the reservoir is established in infancy.

170 st that, contrary to common assumptions, the reservoir is not randomly distributed among cell subsets

171 vity under conditions where the viral latent reservoir is predominantly hosted by peritoneal B cells.

172 PORTANCE Identification and clearance of HIV reservoirs is a major challenge in achieving a cure for

173 rategy which uses chemical bonds as electron reservoirs is introduced to demonstrate the new concept

174 A solid proton reservoir layer, PdH(x), also serves as the gate termina

175 -term ocean-atmosphere-sediment carbon cycle reservoir (LOSCAR) model.

176 reveals that the nuclear envelope acts as a reservoir, maintaining COP1 poised for action.

177 , Permian) is ~15x higher than that from gas reservoirs (Marcellus).

178 The removal of dams and reservoirs may seem to be an unforeseen and sometimes co

179 and alternative strategies to eradicate this reservoir must be sought.IMPORTANCE Efforts to cure HIV

180 human immunodeficiency virus type 1 (HIV-1) reservoirs occurs early in infection, and biomarkers of

181 present in the UK group may provide a robust reservoir of anti-feeding deterrents to mitigate future

182 The effects on the gut resistome, a reservoir of antimicrobial resistance genes in the body,

183 Microbial secondary metabolism is a reservoir of bioactive compounds of immense biotechnolog

184 The extracellular matrix encompasses a reservoir of bioactive macromolecules that modulates a c

185 Platelet-rich fibrin (PRF) serves as a reservoir of bioactive molecules to support wound healin

186 Bacterial toxins represent a vast reservoir of biochemical diversity that can be repurpose

187 acteria are an enormous and largely untapped reservoir of biosensing proteins.

188 uencing of actinomycetes reveals an untapped reservoir of biosynthetic gene clusters, but prioritizat

189 Earth's core is likely the largest reservoir of carbon (C) in the planet, but its C abundan

190 opical peat forests are a globally important reservoir of carbon, but little is known about CO(2) exc

191 in MSCs, which serve as a long-term natural reservoir of dormant M. tuberculosis.

192 Mycobacteriophages thus present a massive reservoir of genes for identifying mycobacterial essenti

193 liminate the follicular dendritic cell (FDC) reservoir of HIV-bound immune complexes (ICs) is unknown

194 infection will require the elimination of a reservoir of infected CD4+ T cells that persists despite

195 Few studies have addressed the unique reservoir of infectious HIV that exists on follicular de

196 iscovery in 1976 of waterfowl as the primary reservoir of influenza A viruses (IAVs) has since spurre

197 Both modules harbor a reservoir of latent dynamics, and their interaction form

198 eive antiretroviral therapy (ART) owing to a reservoir of latently infected cells that contain replic

199 be because of the very early formation of a reservoir of latently infected cells.

200 fection due to the existence of a long-lived reservoir of latently infected cells.

201 servations that demonstrate it to be a major reservoir of marine sulfur.

202 dix may play an active physiologic role as a reservoir of methanogens.

203 Soils represent the largest terrestrial reservoir of organic carbon, and the balance between soi

204 koth formed from a homogeneous or well-mixed reservoir of solids.

205 ity of folded RNAs offers a nearly unlimited reservoir of targets for small molecules to bind, simila

206 aterrestrial iron sulfide is a major mineral reservoir of the cosmochemically and astrobiologically i

207 human oral cavity contains a poorly explored reservoir of these genes.

208 ville, suggesting that there may be a larger reservoir of unmeasured ROC at the former site.

209 on of non-genic transcripts, which exposes a reservoir of variable polypeptides to natural selection.

210 t varies among mammalian species, granting a reservoir of young cells for the cerebral cortex.

211 Bats are presumed reservoirs of diverse coronaviruses (CoVs) including pro

212 integration sites, we show that the proviral reservoirs of elite controllers frequently consist of ol

213 r, these results reveal bats to be important reservoirs of exogenous KoRV-related gammaretroviruses.

214 n primate animal models and to known natural reservoirs of filoviruses, and metagenomic sequencing ca

215 which have the potential of exposing hidden reservoirs of HIV-1 to elimination by the immune system.

216 s new insights on the potential locations of reservoirs of HIV-infected cells that persist during the

217 kely to act as keystone hosts and constitute reservoirs of infection that can spill over into other s

218 and Actinomyces are key potential microbial reservoirs of macrolide resistance including the ermX, e

219 via a common blood substitute through their reservoirs of medium and endothelium-lined vascular chan

220 ing native soil phosphorus (P) and the large reservoirs of residual P accumulated over decades of cul

221 and respiratory ciliated cells as potential reservoirs of the SARS-CoV-2 receptor.

222 for HIV-1, presumably due to the presence of reservoirs of the virus.

223 the free-living survival of pathogens across reservoirs of various kinds and quantifying the extent t

224 ife history traits can help predict wildlife reservoirs of zoonoses and the vulnerability of populati

225 faces between people, livestock and wildlife reservoirs of zoonotic disease.

226 Most efforts to predict novel reservoirs of zoonotic pathogens use information about h

227 To directly test whether such "special reservoirs" of zoonoses exist, we used literature search

228 nogenesis in already heavily biodegraded oil reservoirs, oil sands samples were amended with nutrient

229 to estimate the size of the residual latent reservoir on ART.

230 ate the performance of EOR surfactants via a Reservoir-on-a-Chip approach, which uses microfluidic de

231 re sourced from the laterally extensive deep reservoir only.

232 a higher stiffness state that prevents inter-reservoir or leakage of the loads from the respective aq

233 uggest a role for better surveillance in its reservoirs or vectors, especially in remote regions wher

234 the molecular characteristics of the HIV DNA reservoir over time during antiretroviral treatment (ART

235 eruptions at Axial Seamount are triggered by reservoir overpressurization.

236 e, which serves as a rapid-response hydrogen reservoir, oxygen scavenger, sensor for power demand, an

237 icient methods to accurately quantify latent reservoirs, particularly in pediatric studies where samp

238 ced gas-phase emissions from condensed-phase reservoirs partitioned to airborne particles, contributi

239 AFL-assisted powder reservoir patch delivery involves no complex powder form

240 sustained drug delivery, AFL-assisted powder reservoir patch delivery showed a good safety.

241 Enlarging reservoir patch size to 10 cm(2) can conveniently expand

242 cies wherein they maintain a diverse natural reservoir, posing a risk to humans through the occasiona

243 The homopolymer designs have a drug reservoir potential of well over a year at mg/day dosing

244 redictable eruption pattern suggests a magma reservoir pressure threshold at which eruptions occur, a

245 Models consistently predict eruption at a reservoir pressure threshold of 12-14 MPa regardless of

246 n energy or oxygenation, and the analysis of reservoir quality given the impact of burrows on porosit

247 Reservoir reduction as an adjunct to other therapies mig

248 e hydro-fluctuation belt of the Three Gorges Reservoir Region, China, exhibited distinct patterns of

249 d and resolved in both the filament core and reservoir regions.

250 struct the largest existing dataset of virus-reservoir relationships, consisting of the avian and mam

251 ow-level persistent HIV replication in these reservoirs remains detectable, which contributes to neur

252 EPOCH-vorinostat did not eliminate HIV reservoirs, resulted in more frequent grade 4 neutropeni

253 ore surfaces are representative of carbonate reservoir rock.

254 igured in the microscopic pore spaces of the reservoir rock.

255 The occurrence of zeolite in Corriental reservoir sediments expands our understanding of the ear

256 ay be key contributors to the HIV/SIV latent reservoir, since they harbor high levels of HIV/SIV; rev

257 The spleen acts as a reservoir site for hematopoietic stem and progenitor cel

258 y be a practical initial indirect measure of reservoir size in the peripheral blood of children with

259 These organisms form an oil-reservoir specific clade based on the phylogenies of bot

260 injectivity and potentially compromises the reservoir storage integrity through pore fluid pressure

261 at the conditions of gas formation or during reservoir storage, becoming indistinguishable from equil

262 Impaired right atrial (RA) reservoir strain and elevated estimated RA pressure were

263 iabetes and LVEF >=35% (n = 237), GLS and LA reservoir strain below median were significantly associa

264 as the ratio of echocardiographic E/e'-to-LA reservoir strain.

265 ribe the design and testing of a long-acting reservoir subcutaneous implant capable of releasing cabo

266 s C, mimicking the cooling in subsurface oil reservoirs subjected to seawater injection.

267 trations, one may suppose that conditions in reservoirs, such as sulfate limitation, trigger metaboli

268 Thus, LECs may serve as a proficient viral reservoir that provides viral progeny for continuous de

269 allenge due to cellular and anatomical viral reservoirs that are often protected from treatment by ef

270 HIV-1 persists in cellular reservoirs that can reignite viremia if antiretroviral t

271 ates are large, climate-sensitive old carbon reservoirs that have the potential to emit large quantit

272 border, U.S.A.) encompasses three successive reservoirs that seasonally stratify, creating anoxic con

273 HIV persists in cellular and anatomical reservoirs that show minimal decay during ART.

274 cation and/or latent HIV reactivation in CNS reservoirs, thereby reducing HIV-associated neuroinflamm

275 V replication and/or HIV reactivation in CNS reservoirs, thereby reducing neuroinflammation and neuro

276 t state could accelerate the decrease in the reservoir, thus reducing the time to eradication.

277 reveals that neutrophils serve as an energy reservoir to fuel breast cancer lung metastasis.

278 GAS proteases and could therefore serve as a reservoir to maintain steady-state levels of CXCL1 in in

279 of lean mice serve as a substrate buffer or reservoir to modulate lipid, catecholamine, and iron ava

280 in patients, diversify clonally and serve as reservoirs to drive relapse, recurrence or progression t

281 ns have illustrated that these are excellent reservoirs to host organic compounds against the harsh s

282 -water contact within an isolated subglacial reservoir) up to 20 times higher than that found in mari

283 nd permissiveness of the monocytic host cell reservoir via regulation of IFN-gamma and IL-10.

284 cted women during ART may sustain HIV tissue reservoirs via Ag exposure or HIV replication.

285 sence of a (34)S-depleted pore water sulfide reservoir, via closed system (Raleigh-type) fractionatio

286 Measurement of the frequency of reservoir viruses capable of outgrowth in the presence o

287 th of a substantial but variable fraction of reservoir viruses is blocked by autologous contemporaneo

288 dinal measurements available, the HIV latent reservoir was not detected post-alloBMT in four patients

289 Germany's largest drinking water reservoir was sampled for 1 year, and DOM processing in

290 n to LNs, in the CNS, the size of latent SIV reservoirs was higher in the CD11b+ microglia/macrophage

291 between SARS-CoV-2 and the bat sarbecovirus reservoir were estimated as 1948 (95% highest posterior

292 e containing polymeric films and lyophilised reservoirs were assessed as drug reservoir candidates.

293 py-free remission, even though deeper tissue reservoirs were not targeted.TRIAL REGISTRATIONNot appli

294 tion substantially reduces the long-term HIV reservoir when complete donor chimerism is established.

295 torage, this "super-LUMO" serves as an empty reservoir, which can be filled by a two-electron reducti

296 s since 1950 promoted sediment deposition in reservoirs, which is thought to be starving the coast of

297 n/dearomatization shuttle, or as an electron reservoir with reversible redox activity.

298 ew the concept of targeting the HIV-1 tissue reservoirs, with an emphasis on the central nervous syst

299 , has potential for reducing the size of HIV reservoirs within the mesenteric lymphatic system.

300 were developed for conventional oil and gas reservoirs would require empirical parameters to be cali