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1 is readily degraded, while S100A8/S100A9 is resistant.
2 isolates from 4,038 patients were carbapenem-resistant.
3 ffected by benzoxazinoids, most showed to be resistant.
4 ophoblast cultures, which are otherwise ZIKV resistant.
5 are multidrug-resistant (MDR) or rifampicin-resistant.
6 or - rather than the auxin transporter AUXIN RESISTANT 1 (AUX1) - was considered to precede auxin-ind
7 r its interacting partner malin, degradation-resistant abnormally structured insoluble glycogen accum
8 ts of PRF membranes as indicated by tartrate-resistant acid phosphatase (TRAP) staining and pit forma
9 /4 [BMP2/4], osteocalcin [OCN], and tartrate-resistant acid phosphatase [TRAP]) analyses were perform
10 (from 24.15 to 15.76 per 10,000), carbapenem-resistant acinetobacter species infection (from 3.33 to
11 her the in vitro susceptibility of multi-NAI-resistant AIVs is associated with in vivo susceptibility
12 induced necrosis in several mutant and FLT3-resistant AML cell lines and primary blasts from AML pat
14 erstand the evolution of novel antimicrobial resistant (AMR) S. sonnei variants after introduction in
15 spectrum in vitro activity against multidrug-resistant and extensively drug-resistant bacteria, inclu
16 d the conversion of the mutated C1 into a PK-resistant and infectious form perpetuating the biochemic
17 0 experimentally supported circulating, drug-resistant and prognosis-related lncRNA biomarkers; (ii)
18 hat RUNX1(+) PLCs is an intrinsic castration-resistant and self-sustained lineage that emerges early
20 SNPs for Sbwm1 can effectively separate the resistant and susceptible lines in a new diversity panel
21 assessing a large and diverse collection of resistant and susceptible patient isolates collected fro
22 tibilities, 231/331 (69.8%) were methicillin resistant, and the proportion did not change by year.
24 nce, spread and persistence of antimicrobial-resistant (AR) bacteria, but their relative contribution
25 ction against clinical malaria in pyrethroid-resistant areas compared to standard pyrethroid-only LLI
26 n and AHR in a mouse model of severe steroid resistant asthma, potentially through the accumulation o
28 emergence of deadly pathogens and multidrug-resistant bacteria at an alarmingly increased rate, bact
29 biotics for combination therapy against drug resistant bacteria can be realized on an integrated micr
30 gulls are mobile and can shed antimicrobial-resistant bacteria for extended periods, gulls may facil
32 s against two clinically isolated multi-drug-resistant bacteria strains (including carbapenem-resista
34 nst multidrug-resistant and extensively drug-resistant bacteria, including ESBL, carbapenem- and coli
52 use of PARPi in BRCA-competent and olaparib-resistant cancers, making fully small-molecule-induced s
55 er, we find that A3B knockdown re-sensitises resistant cells to cisplatin, and A3B knockout enhances
56 fied schedules on the basis of the number of resistant cells where drug interactions and pharmacokine
57 sitivities, absent in therapy naive or fully resistant cells, suggesting the potential for new therap
62 nds C3 with low nanomolar affinity in an SDS-resistant complex, and the nanobody is demonstrated to b
63 -1 system is known to be impaired in insulin-resistant conditions, and we sought to understand the co
64 s (SEs) that are abnormally activated in Enz-resistant CRPC cells and associated with enhanced transc
65 ine-27 acetylation (H3K27ac) ChIP-seq in Enz-resistant CRPC cells, we identified a group of super enh
66 hybrid strain, a significant decrease of the resistant CYP6P9a-RR genotype was observed after ten gen
67 irst case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transpla
69 n 34 individuals (ages 18-65) with treatment-resistant depression (TRD) who received a single ketamin
73 Both are commonly associated with insulin resistant diabetes, usually accompanied by dyslipidemia
79 d CDI (CO-HCFA-CDI), incidence of vancomycin-resistant Enterococci (VRE) colonization after receiving
81 ant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), Pseudomonas aeruginosa (PA
82 about the population structure of vancomycin-resistant Enterococcus faecium (VREfm) in Latin America
86 rugs for antidepression, resensitize the Enz resistant (EnzR) cells to Enz treatment and further supp
87 and in neocortical parenchyma of young, drug-resistant epilepsy patients (18-28 years old) who underw
89 stant bacteria strains (including carbapenem-resistant Escherichia coli and methicillin-resistant Sta
91 Here we show that inappropriate, learning-resistant fear behavior results from disruption of brain
93 e presurgical evaluation, patients with drug-resistant focal epilepsy were instructed to overtly expl
96 ith respect to the transmission of multidrug-resistant gastrointestinal pathogens and the risk of tre
97 otic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in human gut microbiota have sign
98 virus infection model and selection for G418 resistant genomes, we demonstrated that Y138 is a critic
100 on incubation method, we measure degradation-resistant glycogen in as little as 30 mg of skeletal mus
101 -b-PDM12 sensitizes carbapenem- and colistin-resistant GNB to multiple antibiotics in vitro and in vi
103 is an opportunistic and frequently multidrug-resistant Gram-negative bacterial pathogen that primaril
110 g directed evolution, we engineered a 'decoy-resistant' IL-18 (DR-18) that maintains signalling poten
113 patterns associated with the susceptible and resistant interactions are highly specific and that nove
116 bal evolution of pathogenicity in carbapenem-resistant K. pneumoniae, resulting in the repeated conve
117 L/6J mice; hyperglycemic, but mildly insulin-resistant, KK mice; and hyperglycemic and markedly insul
118 mice; and hyperglycemic and markedly insulin-resistant KKAy mice were used for ozone exposure studies
119 1 or GFP in the parkinsonian striatum of LID-resistant Lewis or LID-prone Fischer-344 (F344) male rat
121 tence of phylogenetically diverse antibiotic-resistant lineages, widespread geographical mixing, and
122 ro and in vivo growth responses of Abi-/Enza-resistant LNCaP-95 cells in which CRISPR-Cas9 was used t
124 st of Essential Medications for treating non-resistant malaria, rheumatoid arthritis (RA) and systemi
127 aluated the accuracy of the BD MAX multidrug-resistant (MDR)-TB assay (BD MAX) in South Africa, Ugand
128 that PDAC consists of ALDH+/CD133+ and drug-resistant (MDR1+) subtypes of CSCs with specific metabol
129 was itself regulated by MDM2, and in therapy-resistant melanoma cell lines, nuclear accumulation of M
130 d to reduce CD40 relocation to the detergent-resistant membrane domain and to inhibit CD40-induced ph
131 derived cholesterol into transient detergent-resistant membrane domains (DRMs) within the ER, also ca
132 pplementation in middle-aged, obese, insulin-resistant men affects mitochondrial respiration, content
134 inulin prevented worm expulsion in normally resistant mice, instead resulting in chronic infection,
140 These findings were confirmed on bortezomib-resistant multiple myeloma cells as well as on bone marr
141 that the complexes block the G34E amantadine-resistant mutant despite some crowding in the binding si
143 Phylogenetic and network inferences, drug resistant mutations (DRMs), subtypes and HIV-1 diversity
144 ate adenocarcinoma histology to a castration-resistant neuroendocrine prostate cancer (CRPC-NE).
145 ar, but for both H3K4me3 and H3K27me3 in its resistant NIL; (ii) DBSs for H3K27me3 mark were more abu
146 ype of PSCs and are overactivated at disease-resistant NMJs [soleus muscle (SOL)] in SOD1(G37R) mice.
147 7-48 which exhibited greater potency in drug-resistant NSCLC cells (IC(50) = 17 nM) and in mice with
153 e changes in infection rates with antibiotic-resistant organisms in the 2 to 6 years post-implementat
154 UAT result was associated with less frequent resistant organisms, but usually did not lead to antibio
155 enty-eight patients infected with carbapenem-resistant P. aeruginosa isolates susceptible to TOL-TAZ
157 (p = 0.0005) and are more type I interferon-resistant (p = 0.007) than those transmitted to males.
159 -stage survival of wild-type and artemisinin-resistant parasites harboring the PfKelch13:C580Y mutati
162 stant Enterobacteriaceae (CRE) are multidrug-resistant pathogens for which new treatments are despera
165 nically relevant platinum and acquired PARPi-resistant patient-derived xenografts (PDXs) models.
168 Wnt ligand that drives a metastatic, therapy-resistant phenotype, stabilizes the half-life of p53 and
169 rrelations between most of the antimicrobial resistant phenotypes and genotypes observed among the in
171 is driven by tumor heterogeneity and therapy-resistant populations that can reinitiate growth and pro
172 ucted a genomic survey of clinical polymyxin-resistant (PR) Klebsiella pneumoniae to determine the mo
173 udomonas aeruginosa isolates were carbapenem-resistant preimplementation compared with 25.0% postimpl
174 ntravenously for the treatment of castration-resistant prostate cancer (CRPC) as the oral administrat
175 n extremely aggressive variant of castration-resistant prostate cancer (CRPC), is increasing in incid
178 apy among men with nonmetastatic, castration-resistant prostate cancer and a rapidly rising PSA level
179 vival of patients with metastatic castration-resistant prostate cancer and liver metastases assigned
180 ients with progressing metastatic castration-resistant prostate cancer taken prior to starting a stan
183 approximately 15%-20% of advanced treatment-resistant prostate cancers, and this may manifest clinic
185 f beta-lactam antibiotics against carbapenem-resistant Pseudomonas aeruginosa and carbapenem-resistan
188 schedule self-administration and punishment-resistant responding, food reward tolerance and escalati
189 strategies to design next-generation fouling-resistant RO membranes via structural optimization: firs
193 of treatment for 33 patients with treatment-resistant schizophrenia and 31 controls, and processed u
194 microbial pathogens including two antibiotic-resistant species [methicillin-sensitive Staphylococcus
197 Jails may facilitate spread of methicillin-resistant Staphylococcus aureus (MRSA) in urban areas.
199 ve Staphylococcus aureus (MSSA), methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resis
202 temic therapy alone can result in a castrate-resistant state; therefore, increasing focus is being pl
206 ld as toxic as permethrin in four pyrethroid-resistant strains and not significantly less toxic than
207 the mechanisms remain poorly clarified, drug-resistant strains are widely believed to be less infecti
208 olates of N. gonorrhoeae including multidrug-resistant strains at a concentration as low as 0.03 ug/m
209 -term coexistence of both drug-sensitive and resistant strains at intermediate levels, a ubiquitous p
210 bits asexual growth of multiple antimalarial-resistant strains of Plasmodium falciparum (half maximal
211 llent activity against several streptogramin-resistant strains of Staphylococcus aureus, exhibits dec
213 of polymyxins and the emergence of multidrug resistant strains(5), our understanding of the bacterial
214 related classes may occur by co-selection of resistant strains, thus leading to the rapid emergence a
215 nce can originate from heterogeneous, weakly resistant subpopulations with variable sensitivity to di
217 intensive protocols and in populations with resistant symptoms or intolerance to analgesic medicatio
219 rom all six Tau isoforms as well as Sarkosyl-resistant Tau aggregates extracted from cell cultures an
220 ent indicated an increased risk of multidrug-resistant TB (MDR-TB) emerging (8%), compared to drug-se
221 nsuring that all persons diagnosed with drug-resistant TB are started on an appropriate treatment reg
222 diagnosis and optimal treatment of isoniazid-resistant TB are urgently needed to avert the de novo em
223 ampin-susceptible TB accounted for 50% of FQ-resistant TB in South Africa and 83% in Southeast Asia.
224 infectious cause of death globally, and drug-resistant TB strains pose a serious threat to controllin
229 fruits showed that the transgenic lines were resistant to anthracnose disease-causing C. gloeosporioi
230 senescent myofibroblasts, rather than being resistant to apoptosis, are actually primed for apoptosi
231 Moreover, cells with 4E-BP knockdown were resistant to BBR-induced cell death and were resensitize
232 h could explain why the 20rDNA line is hyper-resistant to both bacterial and nematode infections.
234 rial fusion mutants eat-3 and fzo-1 are more resistant to both heat stress and oxidative stress.
236 liferation of two cancer cell lines that are resistant to cancer drugs and diminished ERK signaling.
240 characterized by recurrent seizures that are resistant to conventional anticonvulsant treatment but a
242 eloid cells (Asxl2DeltaLysM) were completely resistant to diet-induced weight gain and metabolically
243 surface is highly flexible, whereas they are resistant to diverging in color composition, presumably
246 atients, 386 had full DST, of which 246 were resistant to ethambutol and 217 were resistant to pyrazi
248 lopment of apple (Malus domestica) cultivars resistant to fire blight, a devastating bacterial diseas
249 d 60% were extensively drug-resistant (XDR), resistant to first-line antibiotics, fluoroquinolones an
250 Here, we found that Trem2(-/-) mice are more resistant to growth of various cancers than wild-type mi
254 roduce both TNFalpha and IL-1beta and highly resistant to lethality in these models, disclosing a com
258 one well established Pan-CoV assay is highly resistant to mutation compared to species-specific SARS-
260 t to RAF/MEK inhibitors (RMi) are frequently resistant to other therapies, such as immune checkpoint
262 xplain why patients with PMNs are frequently resistant to platinum-based chemotherapy and provide TP5
264 ha/Sulfono-gamma-AA peptides were completely resistant to proteolytic degradation, boosting their pot
265 ably, we found that TARK1 CRISPR plants were resistant to Pseudomonas syringae pathovar tomato strain
270 with gestational trophoblastic tumors (GTT) resistant to single-agent chemotherapy receive alternati
272 echanism where accurate individuals are more resistant to social influence (i.e., adjustments to the
274 amounts of PIP(2) in cells renders them more resistant to TAT-RasGAP(317-326), while reducing the abi
275 we demonstrate that post-pregnancy MECs are resistant to the downstream molecular programs induced b
277 astatic sites, breast cancer cells were more resistant to the estrogen receptor modulator tamoxifen a
279 grettably, the global insurgence of isolates resistant to the triazoles, the frontline antifungal cla
282 tions that allow tumors to evolve and become resistant to treatment can be readily identified with a
284 prone to weight gain during overfeeding and resistant to weight loss during caloric restriction.
285 pension can help individuals with medication-resistant tremor, worsening symptoms when the medication
287 Meta-analysis of patients with isoniazid-resistant tuberculosis (TB) given standard first-line an
289 id and pretomanid as new drugs to treat drug-resistant tuberculosis, there is now a renewed interest
292 dienone compounds are cytotoxic to apoptosis-resistant tumor cells and show activity in animal tumor
293 s anti-cancer agents to inhibit chemotherapy-resistant tumor growth by consuming intracellular glutat
295 gest a mechanism for the development of drug-resistant tumors and a target for overcoming resistance.
298 e presented for the selection of insecticide-resistant vectors and the spread of resistance through r
300 ne antibiotics and 60% were extensively drug-resistant (XDR), resistant to first-line antibiotics, fl