ライフサイエンスコーパス: resolution

1 lting in a 3D reconstruction at 1.9 angstrom resolution.

2 -C data with breakpoints at single base-pair resolution.

3 hin discrete brain networks at high temporal resolution.

4 MFDSs) were measured before and after drusen resolution.

5 Peripheral eosinophilia predicted resolution.

6 ctural characterization with high spatial 3D resolution.

7 issect TE expression dynamics at single-cell resolution.

8 of Fab:CHIKV complexes at 4- to 5- angstrom resolution.

9 -EM structure of the complex at 3.5 angstrom resolution.

10 between throughput, sensitivity, and spatial resolution.

11 scale materials with ultimate spatiotemporal resolution.

12 ng spatial force measurements at subcellular resolution.

13 s of viral plaque formation with single-cell resolution.

14 bility over the past four decades at a ~1-km resolution.

15 human motor cortical areas at single-neuron resolution.

16 are placed at mid cell for subsequent dimer resolution.

17 d the two capsids by cryo-EM at 3.5 angstrom resolution.

18 VA) and brolucizumab achieving greater fluid resolution.

19 ield into the vacuum cladding with nanometer resolution.

20 hing robust droplet screening at single-cell resolution.

21 ative mapping of ac(4)C at single-nucleotide resolution.

22 l samples with force sensitivity and spatial resolution.

23 had their structures characterized at atomic resolution.

24 ism Chaetomium thermophilum at 2.6- angstrom resolution.

25 k widths are still dominated by instrumental resolution.

26 ore within the 1-hr resolution than the 3-hr resolution.

27 ect, was never characterized in high spatial resolution.

28 s to identify drivers are limited by spatial resolution.

29 s to >=240 mum in an eye that previously had resolution.

30 onsequently productivity increase with model resolution.

31 nd was structurally resolved at 3.0 angstrom resolution.

32 res of all five compounds with <1.1 angstrom resolution.

33 interactions with single-molecule, nanoscale resolution.

34 of magnitude, leading to much higher spatial resolution.

35 -binding sites at close to single-nucleotide resolution.

36 ack of real-space imaging at single particle resolution.

37 PET MPI agent with superior image and defect resolution.

38 lex with cyclophilin A (CypA) at near-atomic resolutions.

39 ed artery before pPCI or complete ST-segment resolution 1 h after pPCI in patients presenting with ST

40 llenges and opportunities at three scales of resolution: (1) technologies, (2) users and scenarios, a

41 12 glomeruli were reconstructed at an x-y-z resolution ~ 10 x higher than that of paraffin sections.

42 le, is much coarser than the animal's visual resolution (~2 degrees).

43 Using high-resolution 7 T time-of-flight angiography we manually cl

44 noisy 1D and 2D NMR data with high temporal resolution, allowing further analysis by fitting with ki

45 i-BLESS labels DSBs with single-nucleotide resolution, allows detection of ultrarare breaks, takes

46 High-resolution analyses of these two types of QTLs reveal di

47 RNA sequencing (scRNA-seq) has allowed high-resolution analysis of cell-type diversity and transcrip

48 The resolution and accuracy of single-molecule localization

49 re imaging method with sub-capillary spatial resolution and blood flow-resolving speed is lacking.

50 t tissues and can gain power as fine-mapping resolution and cell-specific annotations become richer.

51 These features normalized over the resolution and convalescence phases.

52 on of individual D-loops with near base-pair resolution and deep coverage, while also revealing their

53 Using a combination of confocal, super-resolution and EM, we defined DAT localization and its m

54 d spectra can be obtained with high spectral resolution and fractional monolayer detection limits in

55 volumetric imaging with high spatiotemporal resolution and high dynamic range force capability (10 p

56 fetime imaging targets that require cellular resolution and molecular specificity.

57 ents across tissues have had limited spatial resolution and proteome coverage and have relied on manu

58 dothelial cells and improved venous thrombus resolution and pulmonary vaso-occlusions in End.TGFbetaR

59 ka virus) particles are known to near-atomic resolution and show detailed structure and arrangement o

60 ever, their analysis is challenging, both in resolution and speed.

61 termines the trade-off between the frequency resolution and the number of elements required to achiev

62 re pro-resolving lipid mediators involved in resolution and tissue repair, whose intracellular signal

63 usion and T(2)* at 7T with improved temporal resolution, and demonstrated assessment of spatial and t

64 IR) region are potentially noninvasive, high-resolution, and rapid biological imaging materials.

65 otease, solved the structure at 1.6 angstrom resolution, and refined the model to R (work) and R (fre

66 IR-II signals with high spatial and temporal resolution, and remarkable NIR-II image-guided photother

67 sing method, based on the multivariate curve resolution approach (MCR), to denoise 2D solid-state NMR

68 ectrometry would greatly benefit from higher resolution approaches for intact proteins and their comp

69 interferences, results obtained at low mass resolution are indistinguishable from medium mass resolu

70 established methods with high spatiotemporal resolution are limited by the potential for laser damage

71 Many applications of directional local resolution are possible, and we concentrate here on map

72 odent brains, but there is a lack of spatial resolution as either the tissue samples were homogenized

73 o the environment, especially at low spatial resolution as generated by current retinal prostheses.

74 eved from room-temperature 3D-ED data with a resolution as low as ca. 3.78 angstrom.

75 Studies with high spectral resolutions, as is required e.g. for high-resolution str

76 Using a high-resolution assessment of human pressure, we show that wh

77 ilayer on Cu(111) at 5 K, and imaged by high-resolution atomic force microscopy.

78 ictive for logarithm of the minimum angle of resolution BCVA with averaged images (0.21; P = 0.004),

79 bly of collagen fibrils to be imaged in high resolution beneath an approximately 5-10 nm thick layer

80 Utilizing collimation, 3.6x greater lateral resolution beyond the Fresnel zone limit was achieved.

81 f in spectroscopic measurements between high resolution, broadband coverage, and acquisition time.

82 n iron oxide particle was visualized at high resolution by cryo-EM.

83 positive tumor cells and CTLs with cellular resolution by non-invasive NIR-IIb light sheet microscop

84 er an area of ca. 1000 nm and with a spatial resolution ca. 5 nm to reveal domain morphology and dist

85 High-resolution chromosome conformation capture (Hi-C) analys

86 l clustering different from prevalent single-resolution clustering methods.

87 High-resolution confocal images allowed us to analyze AL inne

88 NanoSPECT/CT(PLUS) to evaluate system energy resolution, count rate performance, sensitivity, collima

89 Here we present the high-resolution cryo electron microscopy structure of the GFL

90 We developed a high-resolution cryo-EM refinement method that divides an ima

91 Here we report a ~3.9 angstrom resolution cryo-EM structure of activated Schizosaccharo

92 The 4 angstrom resolution cryoelectron microscopy (cryo-EM) structure o

93 High-resolution cryoelectron microscopy (cryo-EM) structures

94 latory effect of ATP through a 2.5- angstrom-resolution crystal structure of the BRAF(KD)-14-3-3 comp

95 ognostic value of baseline clinical and high resolution CT (HRCT) findings in patients with severe CO

96 hanges rely on seasonally aggregated, coarse-resolution data.

97 In addition to providing high-resolution descriptions of archaeal chromosome architect

98 ynamics simulations can provide novel atomic resolution details regarding mechanostability and can se

99 ith mass spectrometry to produce a base pair resolution dissection of more than a E. coli promoters i

100 n between KRAS and CRAF, and we provide high-resolution domain mapping on this and other protein-inte

101 acing was achieved, resulting in the highest resolution EGaIn patterning technique to date.

102 The fast development of high-resolution electron microscopy (EM) demands a background

103 technologies have been shown to provide high-resolution electrophysiological recording with high sign

104 Our study reports a unique method of resolution enhancement purely relying on post-printing t

105 In summary, definition of high-resolution enhancer boundaries enables deconvolution of

106 nce and phylogenetic data with gridded, high-resolution environmental layers and computational modell

107 n ethnically heterogeneous population to low-resolution equivalents and tested the ability of the NMD

108 We also perform a high-resolution ex vivo analysis of pre-existing and induced

109 teractions on actin-tropomyosin because high-resolution experimentally determined structures of filam

110 f molecular microenvironments with nanometer resolution, facilitating the discovery of complex and dy

111 Subsequently, high-resolution fluorescence imaging results consolidated the

112 Using high-resolution fMRI, collected within an ultra-high-field (7

113 ur peripheral visual field, and this loss of resolution follows an approximately logarithmic decrease

114 These panels provide genetic resolution for variant discovery and functional characte

115 as well as a point for comparison with high-resolution force spectroscopy experiments.

116 aste within the human brain using ultra-high resolution functional magnetic resonance imaging (MRI) a

117 Using high field (7-tesla), high-resolution functional magnetic resonance imaging in huma

118 ed by cryoelectron microscopy to 3- angstrom resolution, has a similar surface morphology to Penaeus

119 o probe connectivity with cell-type-specific resolution have expanded the understanding of circuit ch

120 ograms to impute/reproduce the measured high-resolution HLA type, using the more common "winner-takes

121 This study demonstrates at single-neuron resolution how motor neurons may help shape threat-rewar

122 y combining its occurrence range with a high-resolution hydrography and the locations of the dams.

123 ctures of purified stable intermediates, low resolution images of cell sections and genetic approache

124 At the same time, quality of super-resolution imaging depends on high label specificity, ma

125 Cryo-OrbiSIMS is applicable to high resolution imaging of a wide variety of non-volatile and

126 green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in behaving anim

127 g speed, providing an efficient way for high-resolution imaging of large extended specimens.

128 on, transport and fusion in vitro with super-resolution imaging techniques, and two-photon microscopy

129 Here, we used three-dimensional high-resolution imaging to investigate the formation of pleom

130 -specific BioID proximity labeling and super-resolution imaging, we identify CEP112 as a basal foot p

131 a convenient and versatile method for super-resolution imaging, which may be routinely used for cell

132 weight metabolite visualization include high resolution imaging, while maintaining sufficient ion num

133 tate quenchers for single-molecule and super-resolution imaging.

134 NA-Seq) that was combined with in situ super-resolution imaging.

135 tudied using atomic force microscopy at high resolution in air and buffer.

136 d RNAs and their binding sites at nucleotide resolution in intact colorectal cancer (CRC) cells.

137 togrammetric data coupled with high temporal resolution in situ acoustic doppler current profile meas

138 single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel trans

139 or fraction of Treg cells sufficient for the resolution in some cases.

140 High-resolution in vivo brain MRI can be used to estimate gen

141 tion, and impaired hallmarks of inflammation resolution, including dampening of the T helper 1 respon

142 S) provides a method to obtain important low-resolution information for integral membrane proteins (I

143 Herein, we report on the use of high-resolution ion mobility spectrometry separations in stru

144 large volumes at high speed and subcellular resolution is a difficult task.

145 The lateral resolution is comparable to that of linear structured il

146 e spatial details in central vision, whereas resolution is poor in our peripheral visual field, and t

147 ctured illumination microscopy and the axial resolution is similar to that of a standard confocal mic

148 At atomic resolution, it becomes possible to extend frustration an

149 Here, using high spatial and temporal resolution live-cell microscopy, we identified a role fo

150 We use high-resolution location data and an integrated step-selectio

151 g was 0.35 logarithm of the minimum angle of resolution (logMAR; optotype equivalent, 20/45; range, 0

152 tion (1.00 logarithm of the minimum angle of resolution [logMAR; Snellen equivalent, 20/200] in 2020

153 High-resolution magic-angle-spinning (1)H NMR spectroscopy (H

154 Our study provides a high-resolution map of eRNA loci through which super-enhancer

155 h stable and unstable VTs delineated by high-resolution mapping.

156 We used HiCorr to compare the high-resolution maps of chromatin interactions from 10 tissue

157 Subnanometer resolution maps of isolated, bound cofilin molecules and

158 action (SPME) fiber, and the inlet of a high-resolution mass spectrometer is described.

159 e-isolation quantitative strategies for high-resolution mass spectrometry (HRMS) combined with profil

160 ylbenzodipyrroles were characterized by high-resolution mass spectrometry (HRMS), NMR, and X-ray crys

161 with liquid chromatography/electrospray/high-resolution mass spectrometry (LC/ESI/HRMS) are gaining i

162 ents of lipids are readily derived from high-resolution mass spectrometry (MS) and tandem-MS (MS(n)),

163 ahigh-performance liquid chromatography high-resolution mass spectrometry (UHPLC-HRMS) supported by 1

164 Ion-chromatography coupled to high resolution mass spectrometry analysis of the 105 samples

165 he use of negative-ionization mode with high-resolution mass spectrometry appeared promising to impro

166 In this study, using a non-targeted high-resolution mass spectrometry approach, a selection of ch

167 hes for standardized processing of ultrahigh-resolution mass spectrometry data of complex molecular m

168 pounds carefully selected based on ultrahigh-resolution mass spectrometry data revealed that, while D

169 The field of high-resolution mass spectrometry has undergone a rapid progr

170 ser desorption ionization, coupled with high-resolution mass spectrometry imaging.

171 Ultrahigh-resolution mass spectrometry is one of the most powerful

172 Lipidome analysis of KSO using high-resolution mass spectrometry showed that trilinoleate (C

173 Multivariate curve resolution (MCR) analysis of Raman spectra can be utiliz

174 ential for multiplexing using a digital high-resolution melt (dHRM) after the digital PCR (dPCR).

175 dy was to adapt a Methylation-sensitive High-Resolution Melting (MS-HRM) approach from dried blood sp

176 ic potency of TGF-beta1 and KGN using a high resolution micropellet model system.

177 nation of imaging approaches including super-resolution microscopy and electron microscopy we identif

178 s been further investigated by genetic, high-resolution microscopy and high-throughput co-immunopreci

179 Single-molecule super-resolution microscopy has developed from a specialized t

180 oth immunogold electron microscopy and super-resolution microscopy showed that ITPR3 in CCA cells was

181 e combine single-molecule tracking and super-resolution microscopy, light-induced subcellular localiz

182 identification that is complementary to high resolution MS/MS.

183 GANs were used to synthesize mammograms at a resolution of 1280 x 1024 pixels by using images from 90

184 resolved the full-energy peak with an energy resolution of 13.9 per cent.

185 ic vesicles (EVs) with an unmatched temporal resolution of 2 s.

186 d bound to phospholipid, ADP or AMP-PNP to a resolution of 3.3-4.1 angstrom and establish a proteolip

187 entified by reaching up the limit of spatial resolution of 35 nm.

188 erature in transient systems with a temporal resolution of 50 fs and for which accurate measurements

189 lities, and after 2 years there was complete resolution of abnormal multifocal reduced diffusion.

190 e that VB theory readily enables a clear-cut resolution of both of these contributions to the bond fo

191 To advance the sensitivity and spatial resolution of cellular force imaging, we developed a for

192 M, and is able to achieve close-to-nanometer resolution of complexes inside crowded cellular environm

193 guanides and/or diamidines or azoles without resolution of disease before starting miltefosine.

194 Timeless protein Tof1 in DRC signalling and resolution of DNA topological stress require distinct N

195 Globally, the coarse spatial resolution of ESMs and their inability to simulate inten

196 Aerosol mass spectrometry improves the time resolution of experimental investigations into these pro

197 4.8 years (range, 1-7 years), outcomes were resolution of exudation or proliferation with return to

198 The resolution of high shear stress through TAVI reduces Mac

199 The main outcome measures were resolution of infection, final visual acuity, tolerance

200 nce of inflammation and tissue repair in the resolution of infection.

201 ical control point for the induction and the resolution of inflammation and to NAAA itself as a targe

202 ursor of several molecules that regulate the resolution of inflammation.

203 dataset, Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage III trial and

204 The primary endpoint was resolution of NASH.

205 ray ionization (EESI) and the ultrahigh mass resolution of Orbitrap for real-time, near-molecular cha

206 ions provide sufficient information for the resolution of outer arm structure motifs with recognized

207 Resolution of Pol II blocking can be as straightforward

208 nterventions is the low temporal and spatial resolution of publicly available administrative data suc

209 to DNA-damaging agents, NUCKS1 controls the resolution of RAD54 foci.

210 ments or clinical samples with the depth and resolution of single-cell RNA sequencing.

211 The time from randomization to resolution of stromal keratitis and uveitis was signific

212 Partial or complete resolution of subretinal fluid was achieved in 93% of pa

213 ion but also as candidate drugs for a faster resolution of such episodes.

214 Complete resolution of symptoms after surgery ranged from 66% to

215 are able to resolve the spatial and temporal resolution of T cell receptor signaling in the context o

216 contribution of neutrophils and monocytes to resolution of the condition and the subsequent developme

217 contact area determines the lateral physical resolution of the measurement, and considering the soft

218 The high spatial and temporal resolution of the reported technique can be used to stud

219 5 patients had near complete (0-5 degrees ) resolution of their tilt.

220 les, and presented superior single base-pair resolution of this assay.

221 exonuclease 1 (EXO1) plays a key role in the resolution of, and replication through, telomeric G-quad

222 ution are indistinguishable from medium mass resolution offering the benefit of increased sensitivity

223 ses has evolved with the application of high-resolution omics screening to populations enrolled in la

224 historic passing of a World Health Assembly resolution on RHD in 2018 now mandates a coordinated glo

225 ce metals, both performed with 40 nm spatial resolution, on primary rat hippocampal neurons.

226 Although ultra-high-resolution opioid receptor crystal structures have revea

227 nsider multiple topologies when phylogenetic resolution or clear apomorphies are lacking.

228 Resolution or decreased size in some lesions resembled f

229 ation of drug effects in vivo at single-cell resolution over days.

230 ISM rainfall variability with multi-decadal resolution over the last two millennia is investigated u

231 ors and simultaneous brain imaging with high-resolution positron emission tomography brain imaging.

232 Here, we apply a high-resolution, pressure-based approach to describe how two

233 This study uses a high-resolution, process-based modeling framework to assess t

234 Using high temporal-resolution proteomics, we compare the relative extent of

235 nimizing the impact on sensitivity on a high-resolution Q-TOF equipped with ETD and an electrospray i

236 aphy, and other modalities are enabling high-resolution reconstructions of cellular and organelle geo

237 ls into Par4(-/-) mice restored inflammation resolution, reduced cardiac rupture incidence, and impro

238 f such transient weak interactions at atomic resolution remains challenging.

239 ppropriate probes to bridge both microscopic resolutions restricts the areas and structures that can

240 erlying primate ovarian aging at single-cell resolution, revealing new diagnostic biomarkers and pote

241 disconnect in situ by utilising high spatial resolution ROV photogrammetric data coupled with high te

242 tigated with electron diffraction and atomic resolution scanning transmission electron microscopy.

243 High-resolution separation of glycan isomers differentiating

244 ted method showed a stable baseline and high-resolution separation of the standards.

245 We converted high-resolution, sequence-based, HLA typing of 310 subjects f

246 object scatter, spectral crosstalk, spatial resolution, spatial registration accuracy, image uniform

247 al resolutions, as is required e.g. for high-resolution strain mapping, and with large wavelength ran

248 In this study, we present the first high-resolution structural data for this human tumor virus an

249 Here we report the first high-resolution structure of a SctK protein family member, Ps

250 the transient subunit association, an atomic resolution structure of an active alpha2beta2 RNR comple

251 nd prM proteins, resulting in a subnanometer resolution structure of capsid proteins within the virus

252 The 1.4 angstrom resolution structure of OLPVR1 reveals remarkable differ

253 human mitochondria, we report ~3.0 angstrom resolution structure of the human mitoribosome, includin

254 Here we present the first high-resolution structure of the receptor type found in muscl

255 The 2.80 angstrom resolution structure reveals the presence of ATP and GMP

256 ap, combined with previously determined high resolution structures and molecular dynamics simulations

257 By probing recent high-resolution structures in the context of functional and b

258 forms and modeling muscle diseases, but high-resolution structures of fruit fly contractile proteins

259 However, high-resolution structures of full-length monomeric M1 and th

260 ntering an exciting time where many new high-resolution structures of large complexes and membrane pr

261 pathways for viruses are inferred from high resolution structures of purified stable intermediates,

262 onstructs and ligand complexes used for high-resolution structures recently revealed that they corres

263 ization of folding energy landscapes at high resolution, studies of structurally complex multidomain

264 Outcomes in the favorable early hypoxia resolution subgroup significantly depended on infiltrati

265 ical systems at experimentally relevant time resolutions, such as those afforded by single-molecule f

266 averaging yields structures to 5.6 angstrom resolution, sufficient to identify secondary structural

267 Using high-resolution synchrotron radiation microtomography (SRmuCT

268 onance spectroscopy (1D and 2D NMR) and high-resolution tandem mass spectrometry (HRMS/MS) analysis.

269 ptide pools were analysed by untargeted high resolution tandem mass spectrometry and the resulting fr

270 tion coupled with liquid chromatography-high resolution tandem mass spectrometry, we have discovered

271 lusion: MUSE DWI is a promising high-spatial-resolution technique that may enhance breast MRI protoco

272 st was used to check that the proposed super-resolution technique yields the highest peak signal-to-n

273 uran assemblages varied more within the 1-hr resolution than the 3-hr resolution.

274 gained the ability to profile tumors with a resolution that allowed for granular assessment of both

275 A high-resolution, three-dimensional, optical imaging technique

276 in architecture at high spatial and temporal resolution through in vivo mouse erythroid differentiati

277 The pivotal one involves a resolution, through the quinine- or quinidine-promoted m

278 crease the available flux of high wavelength resolution time-of-flight neutron Bragg edge imaging at

279 Here, using atomic-resolution, time-resolved in-situ environmental transmis

280 aging (MRSI) 7 Tesla (7 T) provides enhanced resolution to quantify GABA and Glu levels in the thalam

281 functional MRI analyses to increase temporal resolution to seconds and explore transient configuratio

282 We developed a nucleotide resolution transcriptome-wide, single molecule SM-PAT-se

283 papilledema progression, time to papilledema resolution, treatment interventions and final visual out

284 High-resolution ultrasonic spectroscopy (HR-US) was applied f

285 Patients underwent high-resolution ultrasonography of the breast in addition to

286 e recording neural activity with millisecond resolution using magnetoencephalography.

287 ons can be monitored with high spectroscopic resolution using zero-field nuclear magnetic resonance s

288 digital systems with higher sensitivity and resolution, using novel collimator designs based on tung

289 Here, we collect high spatial resolution video of single zebrafish larvae swimming in

290 The structures provide high-resolution views of CMG-DNA interactions, revealing a me

291 to produce complex 3D structures using high-resolution visible light 3D printing, demonstrating the

292 virus assembly and egress at (sub)nanometer resolution were uncovered.

293 ngle-molecule probes, which rapidly degrades resolution with increasing depth.

294 NASH resolution with no worsening of fibrosis was observed in

295 verexpression of SEMA3F delayed inflammation resolution with slower neutrophil migratory speeds and r

296 logical advances are improving the scale and resolution with which we can dissect interactions among

297 d by single-particle cryo-EM at 3.7 angstrom resolution, with the aid of an antibody chaperone acting

298 S(3)/S(4) species, as studied by high energy-resolution X-ray absorption near edge structure (HR-XANE

299 Column experiments imaged with high-resolution X-ray computed tomography are used to measure

300 een made following the 2011 report of a high-resolution X-ray crystallographic structure resolving th