ライフサイエンスコーパス: resolve

1 ranscriptome whose cellular origin is poorly resolved.

2 ms that control these processes remain to be resolved.

3 he group's evolutionary history is not fully resolved.

4 regulated within cells remains incompletely resolved.

5 isk variants linked to brain disease must be resolved.

6 real, but it is less clear how it should be resolved.

7 its correlation with learning have not been resolved.

8 fferent size duplications has not been fully resolved.

9 to highlight key issues that are still to be resolved.

10 , the structure of the holo-MSC has not been resolved.

11 reactions, primarily erythema, which rapidly resolved.

12 g increasingly elaborate sub-complexes to be resolved.

13 hough the VFT heterodimer structure has been resolved(16), the structure of the full-length receptor

14 laser writing on graphene toward a spatially resolved 2D-patterned architecture.

15 possesses a relatively rare(2) and spatially resolved(3) edge-on debris disk extending from about 35

16 This HiCanu assembly correctly resolves 337 out of 341 validation BACs sampled from kno

17 isaccharide isomer mixture, HRdm was able to resolve 5 out of 6 components.

18 ariability of number concentration of source-resolved 50 - 1,000 nm particles and particle mixing sta

19 ds and nearly 19,000 annotated gene sets for resolving 52 experimentally determined developmental tra

20 We resolve a controversy over two competing hypotheses abou

21 Aeroponics is thought to resolve a variety of plant physiological constraints tha

22 de superfused onto hindlimb skeletal muscle) resolved a decreased blood flow and interstitial PO(2) d

23 mple of such computations, an internal model resolves a sensory ambiguity where the peripheral otolit

24 essfully adapted to address the challenge of resolving a cascade of fast and co-occurring redox steps

25 mation of the mid-descending colon typically resolved, a subset showed characteristic stricturing by

26 In this study, a total of 71 eyes with "resolved" (absence of subretinal fluid) chronic CSC at b

27 mouse and human leukocytes abrogated the pro-resolving actions of RvD5n-3 DPA, including the regulati

28 ivated Treg cells (SuperTreg cells) that can resolve advanced autoimmunity, with Brg1 re-expression i

29 Spatially resolved AFM-IR spectra acquired from individual liposom

30 18% of patients, but in most cases, symptoms resolved after oral paracetamol or a short course of pre

31 but more quickly with advancing decay, which resolves ambiguity about the after-life consequences of

32 th m/z differences as small as 1.79 mDa were resolved and identified with high mass accuracy.

33 multiple breakpoints are often difficult to resolve, and predicting their effects on gene expression

34 Our larger, more resolved, and better-evaluated TWiG-based hypothesis sup

35 later, retinal hemorrhages had substantially resolved, and there was optic disc pallor.

36 etween tumor and normal samples is still not resolved, and this hinders the potential clinical applic

37 Here, we report the 1.67-Gb haplotype-resolved assembly of a diploid potato, RH89-039-16, usin

38 microbiota, in facilitating weight loss and resolving associated comorbidities.

39 y, boys and girls were equally likely to has resolved asthma (33% vs 29%).

40 crystallized as a dimer and was structurally resolved at 3.0 angstrom resolution.

41 rent paternal lineages of domestic sheep and resolved, at the global level, their paternal origins an

42 more than 300 daily PM(10) and further size-resolved atmospheric PM samples in the size range from 1

43 enario, inter-regional transfers could fully resolve bed shortfalls.

44 His respiratory symptoms resolved but the diarrhea persisted during a 4-week foll

45 ted after substrate reduction, which is then resolved by a conserved cysteine, Cys-66, or by the nonc

46 east initiation kinetics, which could not be resolved by bulk luminescence kinetics.

47 Herein, this problem is resolved by chemically installing extended pai-rich alte

48 Here, this longstanding conundrum is resolved by demonstrating 100% spatially homogeneous cur

49 ed by six open questions that may need to be resolved by forming a global hydrogen taskforce in order

50 The swine-origin A(H1N1) variant cases were resolved by full genome sequence comparison of the varia

51 Their three-dimensional (3D) position can be resolved by holographic analysis of the diffraction patt

52 s and carbohydrates, which were successfully resolved by HRdm, including two monosaccharide regioisom

53 ration suggests that this uncertainty can be resolved by incorporating additional cues that are predi

54 The complex mixture was resolved by liquid chromatography-tandem mass spectromet

55 soot can be exactly determined and spatially resolved by low-fluence laser desorption ionization, cou

56 cond spike timing in the avian cortex can be resolved by superfast syringeal muscles and that the sen

57 lly when they contain harmonics individually resolved by the cochlea.

58 n frequency components that are individually resolved by the cochlea.

59 (CTA) of the neck because of its ability to resolve calcium and create multiplanar reconstructions.

60 Altogether, our data provide a time-resolved census of neutrophil diversity and gene express

61 Here, we present a time-resolved chemical proteomic strategy to track the early-

62 enetic perturbations, live imaging, and time-resolved ChIP-seq assays in Drosophila embryos were used

63 that measures the cleavage kinetics and time-resolved cleavage products for over 10,000 targets conta

64 In vivo, femoral hematomas resolved completely between days 8 and 9 in littermate c

65 , the versatility of the mechanoreceptor for resolving complex stimuli in diverse daily scenarios is

66 mains are provided alongside their spatially resolved concentration maps.

67 We present shipborne measurements of size-resolved concentrations of aerosol components across oce

68 Our findings resolve conflicting reports on the permeability and gati

69 est that RTEL1 maintains genome stability by resolving conflicts that can arise between the replicati

70 limits of Bessel and Butterworth filters for resolving consecutive transients.

71 Depth-resolved crystallography shows that the Ni films transfo

72 determination of membrane proteins and time-resolved crystallography.

73 periods; and finally, (c) spatially coarsely resolved data sources are unlikely to represent site-lev

74 the human cortex, with single-lead and time-resolved decoding, using a wide range of temporal freque

75 By applying a phylogenomic approach, we resolve deep relationships of the core Chlorophyta (Ulvo

76 and putative therapeutic approaches aimed at resolving detrimental myeloid cell responses in tissues,

77 ngly being requested to confirm injury or to resolve diagnostic uncertainty.

78 that measures of tissue mechanics may better resolve disease-specific differences in adipose tissue f

79 The, so far resolved, disparate structural details have provided ins

80 Lateral dimensions and separation were resolved down to 0.50lambda for hard objects, with tissu

81 isease heterogeneity has proved difficult to resolve due to poor tumor cellularity and extensive geno

82 een them and invokes different mechanisms to resolve each roadblock.

83 acence imparts superior spectral resolution, resolving eight colors in 300-nm width, about 37.5-nm pe

84 Time-resolved emission and transient absorption experiments r

85 ndependently using high-resolution spatially resolved epifluorescence.

86 Via theoretical computation and time-resolved EPR spectroscopy, we confirmed that the ISC of

87 This represents the most highly resolved evidence yet of microevolutionary change within

88 Time-resolved experiments indicate that the critical process

89 logic inflammation and subsequent failure to resolve fibrosis in response to epithelial injury.

90 Time-resolved fluorescence emission and resonance-enhanced se

91 Spectrally resolved fluorescence microscopy on single block copolym

92 Transient absorption and time-resolved fluorescence show that, relative to the lifetim

93 ctroscopic tools such as steady-state & time-resolved fluorescence spectroscopy, Circular Dichroism (

94 of unnatural amino acid incorporation, time-resolved fluorescence, and (19)F nuclear magnetic resona

95 ny terrestrial ecosystems, but remain poorly resolved for many marine ecosystems, particularly those

96 T studies, and anti- and syn-dG(N2-H)(.) are resolved for the first time.

97 this drug despite there being only a single resolved form for almost 70 years.

98 elocity in the literature, the particle-size-resolved fresh filtration efficiency of seven different

99 anging states yield ESR signals that are not resolved from each other within their respective line wi

100 These determinants were resolved further by site-directed mutagenesis.

101 preferentially unwinding RNA:DNA hybrids and resolving G-quadruplex structures.

102 ages using a new dataset of 30,612 spatially resolved gene expression data matched to histopathology

103 r selection from evolutionary histories that resolves genetic linkage.

104 This work exemplifies the value of haplotype-resolved genomes to better explore evolutionary and func

105 of 400 allelic differences between isolates resolved gonococci into discrete and stable core genome

106 n the transformation of rate-place coding of resolved harmonics along the auditory pathway.SIGNIFICAN

107 Complications were limited to three self-resolving hematomas.

108 ach holds tremendous promise in reproducibly resolving hidden cell populations in complex datasets.

109 Selection under conditions that resolve highly active mutants reveals that 23.3% of all

110 Spatial Profiling (DSP) allows for spatially resolved, highly multiplexed quantification of proteins

111 eny across genomes of bioluminescent species resolved how the luciferase cluster was derived by dupli

112 brain parenchyma, allowed high-content time-resolved imaging of cell migration.

113 Time-resolved imaging under these low-light conditions is ach

114 virus infection may persist or spontaneously resolve in different brain regions.

115 NASH resolved in all mice receiving saroglitazar.

116 mic spatial replenishment are identified and resolved in both the filament core and reservoir regions

117 Inflammation that is not resolved in due course becomes a chronic disease.

118 acutely treated mice while more varicosities resolved in mice with delayed treatment.

119 of patients, all lesions on (68)Ga-PSMA PET resolved in response to treatment.

120 e findings highlight the power of temporally resolved in situ cell-surface proteomic profiling in dis

121 e a potentially useful tool for substructure-resolved in vivo habenula imaging, and provide a groundw

122 Here, using atomic-resolution, time-resolved in-situ environmental transmission electron mic

123 rate the capability of TOF-SIMS to spatially resolve individual tens of nanometer large nanoparticles

124 irillum magneticum strain AMB-1 using a time-resolved inductively coupled plasma-mass spectrometry me

125 cence signals gives valuable space- and time-resolved information.

126 benzo[d]imidazole as an electron donor, time-resolved infrared measurements revealed that about 90% o

127 In fact, only 12% of GLUT1 resolved into a highly mobile subpopulation.

128 le-RBD-up conformations dominated at pH 5.5, resolving into a solitary all-down conformation at lower

129 ion, suggesting that a 'tug of war' reliably resolves lagging.

130 Resolvins (D-series and E-series) are pro-resolving lipid mediators involved in resolution and tis

131 ion through wide-field optics in a spatially resolved manner, and this functionality can be added to

132 Among 177 eyes with resolved ME, the cumulative percent with relapse within

133 mages can provide quantitative and spatially resolved measurements of glycolytic flux in tumors that

134 , we examined novel approaches in which time-resolved measurements of reference proteins provide the

135 Despite progress in resolving mechanisms of CaM-Ca(V) feedback, the stoichio

136 X2 induces the production of specialized pro-resolving mediators (SPMs).

137 ation microscopy with the new tension probes resolves membranes well below the diffraction limit.

138 interdisciplinary approach including isotope-resolved metabolomics to show that in Drosophila melanog

139 Genome-resolved metagenomics can help unravel these complex int

140 Using genome-resolved metagenomics, we identified organisms with hgcA

141 py (ULM) permits the reconstruction of super-resolved microvascular images at clinically relevant pen

142 women in which surgery failed to adequately resolve midline pain) and the frequency of operative and

143 sing utility due to its ability to spatially resolve molecular biomarkers directly from sectioned tis

144 omics can provide high-resolution proteoform-resolved molecular fingerprints of diverse cTnI proteofo

145 Spatially-resolved molecular profiling by immunostaining tissue se

146 MR scalar images are replaced with spatially resolved multidimensional spectra.

147 Taken together, our genome-wide data help to resolve multiple contentious sets of relationships among

148 tional equilibrium can be determined by time-resolved NMR.

149 y sensor, activated by glucose limitation to resolve nutrient supply-demand imbalances, critical for

150 We obtained spatially resolved O-PTIR and AFM-IR spectra confirming the presen

151 ales using a model of adaptation and an eddy-resolving ocean circulation climate model.

152 multiple observational platforms and an eddy-resolving ocean model to identify an unrecognized deep f

153 an be assessed and corrected using the depth-resolved OCT signals.

154 PSS), is characterized using multimodal time-resolved operando techniques.

155 extremely crowded, coupling patterns are not resolved, or if symmetry reasons preclude interpretation

156 These results further resolve oxidation-driven structural perturbation of CaM,

157 A chronic or resolved PAMM lesion was defined as inner nuclear layer

158 Spatiotemporally resolved particulate matter (PM) estimates are essential

159 werful tool for the development of component-resolved, patient-tailored AIT for IBH and could be usef

160 is more closely fixed in time using annually resolved patterns of (14)C, modulated by cosmic radiatio

161 Here, a dynamic analysis of the size-resolved PER is conducted through a comparative study of

162 Notably, short-term acute heat stress assays resolved per-colony (genotype) differences that may have

163 ctrometer could enable high-speed spectrally resolved photoacoustic imaging.

164 A powerful approach is angle-resolved photoelectron spectroscopy, whereby the kinetic

165 g a back-gated device architecture for angle-resolved photoemission measurements with a nano-focused

166 Angle-resolved photoemission spectra and DFT calculations show

167 and VI[Formula: see text] measured by angle-resolved photoemission spectroscopy (ARPES).

168 Our angle-resolved photoemission spectroscopy measurements and fir

169 luminescence, light-intensity-dependent time-resolved photoluminescence, and density function theory

170 otoluminescence (PL) imaging and the spatial-resolved PL intensity and lifetime scanning confirm the

171 The spatiotemporally resolved PM estimations produced by the suggested model

172 ange of binding modalities, including highly resolved positioning around splicing signals and mRNA un

173 on Orbitrap platforms at a minimum of 60,000 resolving power (at 400 m/z), and we demonstrate accurat

174 ectrometry continues to be the leader in the resolving power among all mass spectrometry methods.

175 The mass resolving power depends on the uncertainties in both qua

176 Peak anatomical spatial resolving power in both species is approximately 10-11 c

177 21T is demonstrated for the first time: mass resolving power in excess of 1 600 000 (at m/z 400), roo

178 r, we present a new approach to increase the resolving power of a drift time IMS without employing hi

179 cell, it has become possible to achieve the resolving power of more than 10 million at m/q = 1000 wi

180 s wavelength-measurement technique with high resolving power R = 3.4 x 10(6) (i.e., resolution < 0.3

181 echanism in O. wendtii, providing sufficient resolving power to detect the stimuli.

182 In previous work, the mass resolving power was modest, around 30-40.

183 Despite the improved mass resolving power, the measured peak widths are still domi

184 not show a proportional increase in the mass resolving power.

185 Mobility resolving powers of up to 17 are measured for the tetraa

186 o the magnetic subsystem monitored by a time-resolved probe.

187 emoves sources of systematic uncertainty and resolves problems with typical background-correction sch

188 reaction-diffusion modelling and a spatially resolved promoter activation assay to study signal excha

189 To address the need for spatially resolved protease activity profiling in cancer, we devel

190 cryoEM) is becoming the preferred method for resolving protein structures.

191 Past efforts to make spatially resolved proteome measurements across tissues have had l

192 tient group differences when compared to DTI-RESOLVE protocol (SE = 87.88%, SP = 76.92%).

193 ulated by EGF stimulation, we performed time-resolved quantification of the EGF-dependent oxidation o

194 Efforts to resolve quantum states with spectroscopic tools are typi

195 Here, a time-resolved quartz crystal microbalance with dissipation mo

196 variation is an important, but not yet fully resolved question in ecology.

197 l patients, but most reactions were mild and resolved quickly.

198 Phylogenetic studies have resolved Radiodonta (also known as anomalocaridids) as t

199 will require means to establish a spatially resolved relation between ion bombardment time and depth

200 ls due to coincidently-detected cells can be resolved reliably.

201 emonstrate both a positive health impact and resolve remaining safety concerns, wider roll-out could

202 DNA double strand break (DSB) repair and in resolving replication stress.

203 Using time-resolved representational similarity analysis on the EEG

204 Here, we use a combination of atom-resolved scanning probe microscopy and density functiona

205 ch has been used to develop spatiotemporally resolved, sectorally disaggregated fossil fuel CO(2) (FF

206 Here we use time-resolved serial femtosecond crystallography(1) using an

207 unbiased organoid analysis readouts, should resolve several of the current limitations.

208 d-state NMR (SSNMR) experiments, including J-resolved SiH coupling and quantitative (29)Si measuremen

209 of our microfluidic technology to study time-resolved single-cell responses upon PM exposure.

210 By next integrating spectrally resolved single-molecule imaging, we show that this loca

211 Thus, spatially resolved, single-cell analysis can characterize intratum

212 Spatially resolved, single-cell analysis identified the phenotypes

213 levels in seconds, and thereby enables time-resolved, single-molecule, through-space probing of RNA

214 We directly resolve slipping by predominantly two CAG units.

215 these platforms have proven their ability to resolve some of the most challenging regions of the huma

216 To resolve spatial and seasonal variation in species' respo

217 FRAP, however, is limited in its ability to resolve spatial heterogeneity.

218 In this study, we analyzed highly resolved spatial variables in cities, together with case

219 tes bulk metamaterial modes, which have well-resolved spatial-temporal separation owing to the hypebo

220 Microsecond resolved spectra can be obtained with high spectral reso

221 stalline state contributes to provide better resolved spectral components compared to those collected

222 regional baselining, for time- and potential-resolved spectroelectrochemical (SEC) analysis.

223 Herein, steady-state and time-resolved spectroscopic techniques are combined with new

224 around 90% efficiency), as evidenced by time-resolved spectroscopy.

225 n thin films is investigated by polarization-resolved spectroscopy.

226 -capillary spatial resolution and blood flow-resolving speed is lacking.

227 rk offers a new route towards studying phase-resolved spin dynamics and hybrid magnonic systems.

228 symptoms given that most of these conditions resolve spontaneously.

229 ed protein quality control (RQC) system that resolves stalled translation events is activated when ri

230 Time-resolved stomatal conductance measurements using intact

231 We present a 700-year long, near-annually resolved stratigraphic record of hurricane passage near

232 In addition, comparing the newly resolved structure with those of well-investigated cytoc

233 e how fragmentation of THF-doped DOM in APPI resolved subtle differences between riverine DOM that wa

234 etic resonance imaging (fMRI) are capable of resolving such changes and thus should be explored furth

235 g that of the human head domain which we now resolve, suggest that ligand specificity derives from fa

236 Spatially resolved supratopic- and Janus-binding were periodically

237 Here we present a reference of sequence-resolved SVs constructed from 14,891 genomes across dive

238 linical tests and can provide a solution for resolving t-mAb interferences.

239 We resolve the developmental trajectory and transcriptional

240 Here we resolve the function of YAP/TAZ during regeneration of t

241 ctional or case studies that are not able to resolve the longitudinal consequences of individual vari

242 choice towards those which most effectively resolve the obstruction.

243 To resolve the precise connectivity of these circuits, we f

244 cule spectroscopy and microscopy are able to resolve the spatial and temporal resolution of T cell re

245 he operation strategy for 3DI to capture and resolve the VDF within the field of view.

246 Surgical removal of the tumor partially resolved the CFs and contributes to impressive visual ac

247 In this multifaceted study we have resolved the date of the eruption to 431 +/- 2 CE by ide

248 Using cryoelectron microscopy (cryo-EM), we resolved the first three-dimensional (3D) structures of

249 two-dimensional (2D) LiInP(2)Se(6) detectors resolved the full-energy peak with an energy resolution

250 FttA resolves the dichotomy of a prokaryotic gene structure (

251 range of 30 orders of magnitude in mass and resolves the internal structure of hundreds of Earth-mas

252 In conclusion, reduction of GSL metabolism resolves the multi-organ pathology of Bbs2-/- mice by di

253 Remarkably, transcription effectively resolves the PSC, and we predict that this is a conserve

254 rum of the polymer non-backtracking operator resolves the true compartmental structure up to the theo

255 e present cryo-electron microscopy (EM) data resolving the EC1 and EC1+2 domains of human CDHR3 compl

256 However, resolving the extent, diversity, and quantitative impact

257 Nevertheless, resolving the importance of indirect and environmental t

258 -resolution X-ray crystallographic structure resolving the site of catalysis, a protein-bound Mn(4)Ca

259 g modeled for this scaffold was confirmed by resolving the two most potent ligands [(+/-)-47, and (+/

260 To systematically resolve their functional status, we performed a massivel

261 ctural variants (SVs) in the same brains and resolve their precise breakpoints.

262 s to treat five additional patients who also resolved their acute AMR episode and had sustained disap

263 To resolve these issues we directly observed microglia beha

264 he inability of even well-powered studies to resolve these key relationships.

265 It is difficult to resolve these patterns using traditional field approache

266 derstand the differentiating properties that resolve this apparent conflict.

267 Current theories cannot resolve this apparent contradiction.

268 In this work we resolve this disparity, by showing that any amplificatio

269 To resolve this limitation, here we employ a new nonparamet

270 Control via electric fields would resolve this problem, but previous methods(7-9) relied o

271 nt work on spastin and katanin has partially resolved this paradox by showing that these enzymes are

272 Resolving this ambiguity is critical as CaM is enriched

273 Resolving this will provide insights that decipher how t

274 , with their priorly incorporated functions, resolve three bottleneck issues in the CTL epitope prese

275 (TTAGGG)n of telomeres that cannot be easily resolved through sequencing.

276 Annually resolved titanium from an annually laminated sedimentary

277 truct 790 non-redundant genomes, 43 of which resolve to TM7, a member of the Candidate Phyla Radiatio

278 ey enable regulation of microtubule dynamics resolved to subcellular regions within individual neurit

279 Genome-scale technologies that resolve transcript subpopulations in the nucleus and cyt

280 These data revealed time-resolved transcription factor activities and cell-state

281 nes in data generated from various spatially resolved transcriptomic techniques.

282 toacoustic method to impart high accuracy in resolving tumor hemodynamics during bevacizumab therapy

283 We applied PRISM to resolve two developmentally important, but contentious,

284 the reaction between CBT and aminothiols, we resolved two transient intermediates, the thioimidate an

285 Time-resolved two-dimensional spectral imaging was performed

286 may emerge, in part, because persisting can resolve uncertainty.

287 These phenotypes are resolved upon inhibition of endothelial NF-kappaB signal

288 lationships within Pulsatilla were certainly resolved using the complete cp genome sequences.

289 for three eyes (17.6%) due to recurrent non-resolving VH in group I. late recurrent VH occurred in t

290 Twenty-nine cases were resolved via jury trial, 8 of which were associated with

291 Here, we report combined time-resolved vibrational sum frequency generation (TR-vSFG)

292 We describe how these problems can be resolved with a slightly modified form of the MM rate la

293 and lipids at intermediate steps can only be resolved with cryo-electron tomography (cryoET).

294 The majority of biliary complications resolved with endoscopic management.

295 children, malaria is a febrile illness that resolves with time, but in ~1% of cases, for reasons we

296 during Leishmania spp. infection is far from resolved, with some studies showing a protective role an

297 ldwide; for unknown reasons, most infections resolve within two years.

298 In five cases, the myoclonus completely resolved within 2 days of onset, while in three cases, i

299 serious adverse events were reported - both resolved without sequelae and neither was considered rel

300 Here, we report a femtosecond time-resolved X-ray pump/X-ray probe experiment on protein na