ライフサイエンスコーパス: respiratory muscle

1 r atrophy in limb muscles when compared with respiratory muscle.

2 educing the metabolic demands of cardiac and respiratory muscles.

3 lve truncal, neck-flexor, facial, bulbar and respiratory muscles.

4 ic pressure and it increases the load on the respiratory muscles.

5 with activity related to the contractions of respiratory muscles.

6 ry control system or due to paralysis of the respiratory muscles.

7 rons, leading to atrophy of limb, axial, and respiratory muscles.

8 erception of increased work performed by the respiratory muscles.

9 itional/motor control, including that of the respiratory muscles.

10 ts primarily from the loss of innervation of respiratory muscles.

11 tory complications secondary to paralysis of respiratory muscles.

12 in the work output and metabolic rate of the respiratory muscles.

13 ary component in addition to the weakness of respiratory muscles.

14 uscles of vital organs including cardiac and respiratory muscles.

15 ventilator imposes too little stress on the respiratory muscles.

16 consideration when setting PSV to unload the respiratory muscles.

17 reflect in part structural attributes of the respiratory muscles; (2) that the variation of maximal t

18 Respiratory muscle activation was achieved by placing th

19 exercise and associated effects on dyspnea, respiratory muscle activation, and pulmonary gas exchang

20 flow or pressure at the airway opening or in respiratory muscle activation.

21 f tightness were unchanged by the absence of respiratory muscle activity (p = 0.12).

22 isease-specific differences in mechanics and respiratory muscle activity did not influence the key as

23 e vestibular system contributes to adjusting respiratory muscle activity during changes in posture, a

24 he vestibular system contributes to altering respiratory muscle activity during movement and changes

25 tatic pressure tests may not reveal specific respiratory muscle adaptations to disruptions in breathi

26 reathing, and thereby minimize activation of respiratory muscle afferents and motor command, subjects

27 lail chest, interfere with the action of the respiratory muscles-again in a manner unique to each dis

28 s using bioelectrical impedance, quadriceps, respiratory muscle and handgrip strength, and physical p

29 o-IMT) control group on weaning outcomes and respiratory muscle and pulmonary function 28 days after

30 ter fraction of whole-body VO2 towards their respiratory muscles and develop EIAH.

31 %max), quantifies the mechanical load on the respiratory muscles and relates closely to breathlessnes

32 ed a suppression of tone in the postural and respiratory muscles and simultaneously caused a signific

33 quired weakness syndromes affecting both the respiratory muscles and the limb muscles.

34 ter fraction of whole-body VO2 towards their respiratory muscles, and demonstrate EIAH, suggesting wo

35 other tissues, including multiple accessory respiratory muscles, and of course the heart itself for

36 r muscles and, albeit to a lesser extent, in respiratory muscles, and they persisted during chronic t

37 lated by means of the recipient's airway and respiratory muscles, and they provided gas exchange in v

38 = 51-63) underwent comprehensive (invasive) respiratory muscle assessment and evaluation of dyspnea.

39 rmal values and in 293 patients referred for respiratory muscle assessment to compare the two measure

40 te that C-26 cancer cachexia causes profound respiratory muscle atrophy and weakness and ventilatory

41 Our findings demonstrate that respiratory muscle blood flow is increased while the loc

42 dings suggest the presence of a pathological respiratory muscle blood flow steal phenomenon in PH and

43 rk at a given workload in PH commands higher respiratory muscle blood flow, impairing locomotory musc

44 This study was conducted to stimulate respiratory muscles by functional magnetic stimulation (

45 ypothesis that reflexes arising from working respiratory muscle can elicit increases in sympathetic v

46 Weakness of the respiratory muscles can dominate the clinical manifestat

47 An imbalance between work of breathing and respiratory muscle capacity often results in rapid, shal

48 related to physiologic work of breathing and respiratory muscle capacity, should improve application

49 wever, fentanyl also paradoxically activates respiratory muscles causing a potentially lethal effect

50 nd exercise intolerance include skeletal and respiratory muscle contractile and metabolic disturbance

51 aled minute ventilation, and the duration of respiratory muscle contraction assessed by the ratio of

52 is a patient-ventilator interaction where a respiratory muscle contraction is triggered by a passive

53 l, pleural pressures generated during active respiratory muscle contraction, lung resistance and dyna

54 Accessory respiratory muscle deoxygenation was present only in pat

55 led at least 50 adult ICU patients, reported respiratory muscle (diaphragm or intercostal) ultrasound

56 reserving O(2) transport to locomotor and to respiratory muscles during exercise.

57 urons or in coordinating the contractions of respiratory muscles during nonrespiratory responses (e.g

58 of the lung to increase ventilation and not respiratory muscle dysfunction a more attractive explana

59 r, a highly significant relationship between respiratory muscle dysfunction and symptoms of dyspnea.

60 Evidence has accumulated that respiratory muscle dysfunction develops in critically il

61 develop respiratory muscle weakness and that respiratory muscle dysfunction may contribute to the une

62 umans with peritonitis may be predisposed to respiratory muscle dysfunction.

63 rance, which is associated with skeletal and respiratory muscle dysfunction.

64 tient-ventilator asynchrony and do not allow respiratory muscle effort assessment.

65 ometer captures chest wall vibrations due to respiratory muscle effort, known as high-frequency mecha

66 Research on the respiratory muscles embraces techniques of molecular bio

67 reas MV-RDOS score, esophageal pressure, and respiratory muscle EMG did not change as compared with f

68 -RDOS] scores), P(0.1), esophageal pressure, respiratory muscle EMG, and arterial blood gas were comp

69 MV-RDOS score, P(0.1), esophageal pressure, respiratory muscle EMG, and gas exchange.

70 pogonadal and eugonadal patients had similar respiratory muscle endurance times (302 +/- 29 and 313 +

71 Respiratory muscle endurance was measured with an increm

72 rythmias and concurrent myositis, leading to respiratory muscle failure and death.

73 nce in support of one possible mechanism for respiratory muscle failure in emphysema.

74 tricular or sinus block requiring pacemaker, respiratory muscle failure requiring mechanical ventilat

75 e: time to severe arrhythmia, heart failure, respiratory muscle failure, and/or cardiomyotoxicity-rel

76 erated morbidity and mortality consequent to respiratory muscle failure.

77 ized myositis, myasthenia-like syndrome, and respiratory muscle failure.

78 PV in children with acute severe asthma with respiratory muscle fatigue and failure of medical treatm

79 re overweight or obese, populations in which respiratory muscle fatigue can be limiting.

80 keletal muscle MR deficiency led to improved respiratory muscle force generation and less deleterious

81 eakness (Pdi(sniff) < 30 cm H(2)O), abnormal respiratory muscle function (lesser rise in Pdi) and a l

82 These patients had pathologic respiratory muscle function (P=0.005) and decreased insp

83 ing several bedside indicators of bulbar and respiratory muscle function can aid in evidence-based ri

84 virus (HIV), the effects of HIV infection on respiratory muscle function have not been well character

85 Indeed, most clinicians do not evaluate respiratory muscle function in critically ill patients a

86 rage clinicians from having a closer look at respiratory muscle function in critically ill patients.

87 ring and possible implications of monitoring respiratory muscle function in critically ill patients.

88 To test this postulate, we measured limb and respiratory muscle function in nine clinically stable lu

89 uggest a new therapeutic approach to improve respiratory muscle function in patients with respiratory

90 : Inspiratory muscle training (IMT) improves respiratory muscle function in patients with weaning dif

91 No drugs are available to improve respiratory muscle function in these patients.

92 nsation of dyspnea was related to indices of respiratory muscle function including respiratory rate a

93 Impaired respiratory muscle function is the most severe consequen

94 Pulmonary emphysema impairs lung and respiratory muscle function leading to restricted physic

95 This impairment in respiratory muscle function may contribute to the feelin

96 ormal subjects, however, these decrements in respiratory muscle function may result in symptoms of sh

97 s an intact cough reflex as well as adequate respiratory muscle function to generate elevated intrath

98 Respiratory muscle function was assessed by pulmonary fu

99 ance, reducing ventilatory demand, improving respiratory muscle function, and altering central percep

100 LVRS improves not only lung recoil, but also respiratory muscle function, and reduces dynamic hyperin

101 hyperinflation, air trapping, and improving respiratory muscle function, enables the lung and chest

102 Restoration of diaphragm and other respiratory muscle function, irrespective of the method

103 of the interaction between lung function and respiratory muscle function.

104 ce might result from altered IC and impaired respiratory muscle function.

105 nly at the beginning of routinely monitoring respiratory muscle function.

106 muscles, the diaphragm, and heart; limb and respiratory muscle functional improvement; and reduction

107 We hypothesized that dynamic respiratory muscle functional tests reflect distinct ven

108 Heart failure is characterised by limb and respiratory muscle impairments that limit functional cap

109 and imbalance within the diaphragm and other respiratory muscles in emphysema has been considered the

110 s of studying neuronal circuits that control respiratory muscles in humans with better spatial and te

111 enic strains of PRV were injected into these respiratory muscles in nine ferrets; the strain injected

112 , it seems highly appropriate to monitor the respiratory muscles in these patients.

113 Chronic neuromuscular diseases affect the respiratory muscles in varying patterns and degrees.

114 Owing to a greater relative VO2 of the respiratory muscles in women, less of a change in work o

115 siological drivers, the impact of obesity on respiratory muscles-in particular, the diaphragm-has not

116 ientific understanding of ventilator-induced respiratory muscle injury has not reached the stage wher

117 Research on ventilator-induced respiratory muscle injury is in its infancy and portends

118 y care, as complications such as cardiac and respiratory muscle involvement vary greatly.

119 itis indicated that systematic screening for respiratory muscle involvement, coupled with active vent

120 two-step process: the time from diagnosis to respiratory muscle involvement, followed by the time fro

121 In mammals, a key respiratory muscle is the diaphragm, which is innervated

122 nderstanding of disease states affecting the respiratory muscles is necessary for every physician who

123 ition to the diaphragm's role as the primary respiratory muscle, it also plays an under-recognized ro

124 lusion, whilst the diaphragm is an important respiratory muscle, it is likely that dystrophin needs t

125 Session 2 (S2): 5 min NB, 5 min of respiratory muscle loading with inspiratory resistance,

126 s and administration of pharmacotherapy, the respiratory muscles may be rendered almost (or completel

127 ung injury, regional forces generated by the respiratory muscles may lead to injurious effects on a r

128 To avoid different respiratory muscle metaboreflex and arterial chemoreflex

129 To avoid different respiratory muscle metaboreflex and arterial chemoreflex

130 cts of ageing and female sex hormones on the respiratory muscle metaboreflex are unclear.

131 The arterial blood pressure response to the respiratory muscle metaboreflex is greater in older male

132 We conclude the respiratory muscle metaboreflex response is heightened i

133 etically mediated pressor reflex, termed the respiratory muscle metaboreflex, in which young females

134 sed state-dependent changes in breathing and respiratory muscle modulation under urethane anesthesia

135 sses the latest developments in the field of respiratory muscle monitoring and possible implications

136 which include reflex responses recorded from respiratory muscle nerves of the thorax and abdomen.

137 of vestibular-evoked responses recorded from respiratory muscle nerves of the upper airway. as well a

138 ion of airflow (e.g. neuromuscular junction, respiratory muscles or respiratory mechanics) and is not

139 ion, albuterol relieves dyspnea and enhances respiratory muscle output in patients with COPD primaril

140 Accessory respiratory muscle oxygenation was assessed using near-i

141 nn disease) is associated with quadriplegia, respiratory muscle paralysis and death in infancy.

142 also led to morbidity and mortality owing to respiratory muscle paralysis and paralysis in the face o

143 a potential nanotherapy for the treatment of respiratory muscle paralysis resulted from cervical SCI.

144 ith muscle fatigue, n = 11) displayed weaker respiratory muscles (Pdi(max) 61 versus 115 cm H(2)O; p

145 y reported that hypogonadism does not affect respiratory muscle performance and exercise capacity in

146 was to determine if this agent also improves respiratory muscle performance.

147 ropositivity is associated with a decline in respiratory muscle performance.

148 hieved by other mechanisms, such as improved respiratory muscle perfusion.

149 tment algorithm was defined to target a peak respiratory muscle pressure between 5 and 10 cm H2O.

150 tion with load-adjustable gain factors, peak respiratory muscle pressure can be estimated from the pe

151 rements and Main Results: Inflation volumes, respiratory muscle pressure generation, and transpulmona

152 istance to maintain a predefined boundary of respiratory muscle pressure is feasible, simple, and oft

153 We conclude that respiratory muscle pressure production is the predominan

154 .7-1.8) times per day, according to the peak respiratory muscle pressure target range in 91% of cases

155 The peak respiratory muscle pressure, estimated in cm H2O as (pea

156 ning, forced expiratory volumes, and maximum respiratory muscle pressure, leisure-time physical activ

157 The pressure output of the respiratory muscles, quantified as pressure-time product

158 The mechanism of rapid respiratory muscle recovery following spinal trauma occu

159 ion, exercise performance, gas exchange, and respiratory muscle recruitment (estimated by esophageal

160 comotion to minimize antagonistic loading of respiratory muscles, reduce work of breathing and minimi

161 ing factors such as recruitment of accessory respiratory muscles, reduction in REM sleep, and loss of

162 Mead-Whittenberger technique was used, with respiratory muscle relaxation provided by brief manual v

163 of slow fibers, but overall strength of the respiratory muscles remains well preserved.

164 in posture can affect the resting length of respiratory muscles, requiring alterations in the activi

165 gm function in determining the metabolic and respiratory muscle response to arm elevation.

166 both excessive patient effort and excessive respiratory muscle rest.

167 enly had paralysis of all four limbs and the respiratory muscles, resulting in death.

168 We assessed respiratory muscle (RM) and cardiopulmonary function dur

169 se capacity, we evaluated static and dynamic respiratory muscle (RM) function, and dyspnea.

170 with severe COPD occurs as a consequence of respiratory muscle (RM) weakness or fatigue, we would ex

171 pulmonary endpoints that allow assessment of respiratory muscle status, especially in nonambulatory s

172 Nearly 35% of children had diminished respiratory muscle strength (aPiMax </= 30 cm H2O) at th

173 27, 95% confidence interval 0.02, 0.52), and respiratory muscle strength (g = 0.51, 95% confidence in

174 sure during an occlusion maneuver to measure respiratory muscle strength (maximal change in airway pr

175 Measurements of respiratory muscle strength (PImax, 74 +/- 28 versus 50

176 c lateral sclerosis (ALS) and measurement of respiratory muscle strength (RMS) has been shown to have

177 xercise-related symptoms while IMT increased respiratory muscle strength and endurance.

178 Changes in respiratory muscle strength and rates of ICU survival an

179 sts (PFTs), arterial blood gases (ABGs), and respiratory muscle strength as estimated by maximum stat

180 Each respiratory muscle strength assessment individually achi

181 predictive power of invasive and noninvasive respiratory muscle strength assessments for survival or

182 effect of oral magnesium supplementation on respiratory muscle strength by using manuvacuometry and

183 ith significant bulbar involvement, tests of respiratory muscle strength do not predict hypercapnia.

184 Respiratory muscle strength during acute upper respirato

185 Reduced respiratory muscle strength has been reported in chronic

186 at it could usefully be included in tests of respiratory muscle strength in ALS and will be helpful i

187 neuromuscular disease develop reductions in respiratory muscle strength in association with URI.

188 ntation helped improve both the SK score and respiratory muscle strength in pediatric patients with C

189 n COPD is multifactorial, changes in DCO and respiratory muscle strength may contribute to its intens

190 From a previously published report respiratory muscle strength measurements were available

191 In the critically ill, respiratory muscle strength usually has been assessed by

192 Respiratory muscle strength was tested by measuring maxi

193 entional spirometry, lung volumes, DLCO, and respiratory muscle strength were measured.

194 y, body plethysmography, diffusion capacity, respiratory muscle strength, 6-min walk test, and increm

195 ovement in lung function, exercise capacity, respiratory muscle strength, and ventilatory efficiency.

196 of spontaneous breathing trials, measures of respiratory muscle strength, assessment of risk of poste

197 y of life, physical function, peripheral and respiratory muscle strength, increasing ventilator-free

198 ents with COPD performed pulmonary function, respiratory muscle strength, six-minute walk and cardiop

199 owed a linear decline for direct measures of respiratory muscle strength, whereas VC showed little to

200 tubation failure, with specific attention to respiratory muscle strength.

201 ratory problems, including: (1) reduction in respiratory muscle strength; (2) airways hyperresponsive

202 cal evaluations of extremity, hand grip, and respiratory muscle strength; anthropometrics (height, we

203 ate O2 supply and O2 demand in locomotor and respiratory muscles, subjects performed both maximal con

204 nation, complete pulmonary function testing, respiratory muscle testing, cardiopulmonary exercise tes

205 These patterns include the respiratory muscles that, in both birdsong and speech, p

206 e airways interferes with the ability of the respiratory muscles to generate subatmospheric pressure

207 thing depends on coordinated activity of the respiratory muscles to generate subatmospheric pressure.

208 This novel mechanism of treating respiratory muscles to prevent cardiomyopathy in dystrop

209 ss of intercostal muscles, reorganization of respiratory muscles to the ventral side of the ribs, (su

210 rate and variability and with modulation of respiratory muscle tone.

211 ned but respond to aggressive whole-body and respiratory muscle training with an improvement in stren

212 Significant variations exist in the use of respiratory muscle ultrasound in intensive care with no

213 ercise endurance improvements accompanied by respiratory muscle unloading and dyspnea reductions in p

214 monstrate improved locomotor blood flow with respiratory muscle unloading during activity.

215 (S1): 5 min of normal breathing (NB), 5 min respiratory muscle unloading with a ventilator, and 5 mi

216 output and oxygen uptake is disrupted during respiratory muscle unloading.

217 vels ranging from 7 to 25 cm H2O in terms of respiratory muscle unloading.

218 mbered, nasal O(2), and NIOV+Air, signifying respiratory muscle unloading.

219 alpha causes atrophy and loss of function in respiratory muscle, we asked whether transgenic mice dev

220 Because these neurons innervate respiratory muscles, we hypothesized that respiratory de

221 2) 67 versus 104% predicted; p < 0.0001) and respiratory muscle weakness (PI(max) 77 versus 115% pred

222 Patient 1 had cervical, limb girdle, and respiratory muscle weakness and died of respiratory fail

223 Impaired lung function, respiratory muscle weakness and exercise intolerance are

224 pothesized that HIV+ individuals may develop respiratory muscle weakness and that respiratory muscle

225 ssociated with relevant axial, proximal, and respiratory muscle weakness but without vocal cord palsy

226 In motor neurone disease (MND), respiratory muscle weakness causes substantial morbidity

227 g function tests revealed progressive global respiratory muscle weakness detectable from the time of

228 Respiratory muscle weakness frequently develops during m

229 nale: A model for stratifying progression of respiratory muscle weakness in amyotrophic lateral scler

230 Although respiratory muscle weakness is a known predictor of poor

231 e and early treatment for cardiomyopathy and respiratory muscle weakness is advocated because early t

232 Respiratory muscle weakness is the primary cause of resp

233 agm atrophy and contractile dysfunction, and respiratory muscle weakness is thought to contribute sig

234 had mucocutaneous involvement, skeletal and respiratory muscle weakness, and myalgia that negatively

235 reduced chest wall motion in the presence of respiratory muscle weakness.

236 y representing the earliest manifestation of respiratory muscle weakness.

237 necrosis, leading in many patients to fatal respiratory muscle weakness.

238 ion included predominant distal, proximal or respiratory muscle weakness.

239 , young adult females, with bulbar, neck, or respiratory muscle weakness.

240 d near infrared spectroscopy of an accessory respiratory muscle were obtained during exercise.

241 ow, as well as electromyographic activity in respiratory muscles were recorded in combination with lo

242 heart failure, pulmonary factors, including respiratory muscle work and airflow turbulence, contribu

243 or [2] clinical signs suggestive of intense respiratory muscle work and/or labored breathing) if it

244 Greater respiratory muscle work at a given workload in PH comman

245 blood flow; and reducing the normal level of respiratory muscle work during heavier intensity exercis

246 part, due to the accompanying high levels of respiratory muscle work.