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1 ERS) coronavirus causes a highly fatal lower-respiratory tract infection.
2 ve ability increase risk of dying from lower respiratory tract infection.
3 n cognitive ability and mortality from lower respiratory tract infection.
4 at resulted in two bacteremias and one lower respiratory tract infection.
5 vg+) phase that are necessary for successful respiratory tract infection.
6 on following a primary diagnosis of an upper respiratory tract infection.
7 rs), 414 (47%) were women, and 379 (43%) had respiratory tract infection.
8  for Haemophilus colonization and subsequent respiratory tract infection.
9 ial virus (HRSV) is a major cause of serious respiratory tract infection.
10  clinical presentation was frequently a mild respiratory tract infection.
11 dverse events were nasopharyngitis and upper respiratory tract infection.
12 ommon adverse events were headache and upper respiratory tract infection.
13 actor for the development of recurrent upper respiratory tract infections.
14 cept were injection-site reactions and upper respiratory tract infections.
15 nt of adults with bronchiectasis and chronic respiratory tract infections.
16             They often precede serious lower respiratory tract infections.
17             Numerous viruses can cause upper respiratory tract infections.
18 a exacerbations, and hospital attendance for respiratory tract infections.
19 escribing of antibiotics for childhood upper respiratory tract infections.
20 ide and represent the leading cause of upper respiratory tract infections.
21 nriched in clinical isolates associated with respiratory tract infections.
22 the appropriate use of antibiotics for acute respiratory tract infections.
23 rum antibiotics for most children with acute respiratory tract infections.
24 n children for the prevention of viral upper respiratory tract infections.
25 ae (NTHI) is the causative agent of multiple respiratory tract infections.
26 tion did not reduce overall wintertime upper respiratory tract infections.
27 ospitalized patients <2 years old with lower respiratory tract infections.
28 gic association in persons with severe lower respiratory tract infections.
29 t common indications were skin disorders and respiratory tract infections.
30 in D levels and a higher risk of viral upper respiratory tract infections.
31 ts frequently present to doctors with severe respiratory tract infections.
32 sitive and culture-negative sepsis and lower respiratory tract infections.
33 f future hospital admission in children with respiratory tract infections.
34 appropriate antibiotic prescribing for acute respiratory tract infections.
35 enza virus (PIV) is a leading cause of lower respiratory tract infections.
36 articular concern in the management of lower respiratory tract infections.
37 piratory syncytial virus (RSV)-induced lower respiratory tract infections.
38 method for detection of pathogens from lower respiratory tract infections.
39 ult patients with bronchiectasis and chronic respiratory tract infections.
40  in patients with bronchiectasis and chronic respiratory tract infections.
41 a (13 [12%]), headache (11 [10%]), and upper respiratory tract infection (11 [10%]).
42 dverse events in all groups were viral upper respiratory tract infection (14-16%) and worsening asthm
43 ction (19 [7%] vs 11 [4%] vs 13 [5%]), upper respiratory tract infection (15 [5%] vs 15 [5%] vs 11 [4
44 on (343 [45%] infections), followed by lower respiratory tract infections (171 [22%]), gastrointestin
45 two studies, 1 681 020 events) and for lower respiratory tract infections (-18.48% [-32.79 to -4.17];
46 s), and rates of hospital attendance for all respiratory tract infections (-3.45% [-4.64 to -2.25]; t
47 h dupilumab compared with placebo were upper respiratory tract infections (33-41% vs 35%) and injecti
48 haryngitis (30 [11%] vs 15 [11%]), and upper respiratory tract infection (35 [12%] vs ten [7%]).
49    The most common adverse events were upper respiratory tract infection (36 [10%] patients) and head
50 rse events included fatigue (62%), and upper respiratory tract infection (42%), infusion reactions (4
51 fections (54 [19%] of 278 patients had upper respiratory tract infections; 42 [15%] had bronchitis, 3
52 re infusion reactions (56 [38%] vs 0), upper respiratory tract infections (43 [28%] vs 26 [17%]), and
53 revalent ARI syndromes included: viral upper respiratory tract infection (47%), pharyngitis (18%), an
54 te ratio, 0.85; 95% CI, 0.79 to 0.91), upper respiratory tract infections (4893 vs. 5763 episodes; in
55 confirmed RSV ARTI (includes upper and lower respiratory tract infections), 500 without and 50 with c
56 , headache (57 [15%] vs 46 [12%]), and upper respiratory tract infection (51 [13%] vs 30 [8%]).
57 ost common adverse events overall were upper respiratory tract infection (51 [9%] of 581 patients rec
58 ts were fatigue (25%), headache (13%), upper respiratory tract infection (8%), and arthralgia (8%).
59                                        Acute respiratory tract infections account for the majority of
60 5.2%]; placebo, 89 events [5.0%]), and upper respiratory tract infection (aclidinium, 86 events [4.8%
61 c-inappropriate diagnoses (nonspecific upper respiratory tract infections, acute bronchitis, and infl
62 , 2.75; 95% CI, 2.03 to 3.73), current upper respiratory tract infection (adjusted odds ratio, 1.35;
63 ong the most important causes of acute lower respiratory tract infection (ALRI) in young children.
64 t hospitalizations for all-cause acute lower respiratory tract infection (ALRI).
65 dren worldwide, commonly through acute lower respiratory tract infections (ALRI).
66 al virus (RSV) is the leading cause of lower respiratory tract infection among infants and young chil
67 yncytial virus is the leading cause of lower respiratory tract infection among infants.
68 ate with the incidence and severity of acute respiratory tract infection and childhood asthma develop
69 d high risk of future hospital admission for respiratory tract infection and could be used to reduce
70 180 days to assess outcomes related to lower respiratory tract infection and for 364 days to assess s
71 g viral pathogen associated with acute lower respiratory tract infection and hospitalization in child
72           It is a major cause of acute lower respiratory tract infection and is associated with signi
73 y elective CS had an increased risk of lower respiratory tract infection and juvenile idiopathic arth
74 ic patterns of AWaRe antibiotic use in lower respiratory tract infection and neonatal sepsis were obs
75 anisms provide new insights into herpesvirus respiratory tract infection and pathogenesis.IMPORTANCE
76  months and 12 years diagnosed with an acute respiratory tract infection and prescribed an oral antib
77 er fashion as regards risk factors for lower respiratory tract infection and there is evidence that t
78  three common viruses implicated in seasonal respiratory tract infections and are a major cause of mo
79 general nontuberculosis morbidity, including respiratory tract infections and atopic diseases.
80 nt siblings presenting with recurrent severe respiratory tract infections and bronchiectasis.
81 tions, events that are often associated with respiratory tract infections and cold symptoms.
82                                    Bacterial respiratory tract infections and exacerbations of chroni
83 esent in the nasal mucosa during acute viral respiratory tract infections and further characterize th
84 cytial virus (RSV) is a major cause of lower respiratory tract infections and hospital visits during
85 us (RSV) is the leading cause of acute lower respiratory tract infections and hospitalizations in inf
86 ewer medically attended RSV-associated lower respiratory tract infections and hospitalizations than p
87 teroid-insensitive asthma is associated with respiratory tract infections and noneosinophilic endotyp
88 , influenza, and respiratory syncytial virus respiratory tract infections and ovalbumin-induced, seve
89 um antibiotics and those admitted with lower respiratory tract infections and skin and soft tissue in
90 um antibiotics and those admitted with lower respiratory tract infections and skin and soft tissue in
91 ietary supplements, primarily to treat upper respiratory tract infections and to support immune funct
92 which were nasopharyngitis, influenza, upper respiratory tract infection, and headache.
93 verse events were injection-site pain, upper respiratory tract infection, and nausea.
94 %]), febrile neutropenia (five [10%]), lower respiratory tract infection, and pneumonia (each three [
95 iratory tract illnesses, time to first upper respiratory tract infection, and serum 25-hydroxyvitamin
96 d placebo groups were dyspnoea, cough, upper respiratory tract infection, and worsening of IPF; and t
97 nd susceptibility to allergic sensitization, respiratory tract infections, and asthma.
98 r respiratory tract infections, severe lower respiratory tract infections, and exacerbations of under
99 isodes of troublesome lung symptoms, asthma, respiratory tract infections, and neonatal airway immuno
100            Infusion-related reactions, upper respiratory tract infections, and oral herpes infections
101  tobacco smoke, controller medication, upper respiratory tract infections, and seasonality.
102                                        Viral respiratory tract infections are associated with asthma
103                                              Respiratory tract infections are frequent causes of hosp
104                                              Respiratory tract infections are often viral and but are
105                                              Respiratory tract infections are one of the leading caus
106                                        Viral respiratory tract infections are the main causative agen
107                                        Viral respiratory tract infections are the most common human a
108                      Although non-CAAP lower respiratory tract infections are usually not considered
109 y-confirmed antibiotic-resistant urinary and respiratory-tract infections are more likely to experien
110                                        Acute respiratory tract infections (ARI) constitute a substant
111 s to identify biomarkers of severe RSV acute respiratory tract infection (ARTI) in infants.
112 elines on antibiotic prescriptions for acute respiratory tract infection (ARTI) in PEDs.
113                                        Acute respiratory tract infection (ARTI) is the most common re
114 cohort to obtain incidence data on RSV acute respiratory tract infection (ARTI).
115 t support use of systemic steroids for acute respiratory tract infections (ARTIs), but such practice
116 didates were efficacious in preventing lower respiratory tract infection as well as in reducing the n
117 used Bordetella pertussis, a common neonatal respiratory tract infection, as a proof of concept to in
118                       Asthma-, allergy-, and respiratory tract infection-associated phenotypes (inclu
119  and the secondary end points included lower respiratory tract infections, asthma exacerbations, ecze
120 riate antibiotic prescribing for acute upper respiratory tract infections (AURIs) requires a better u
121 e number of laboratory-confirmed viral upper respiratory tract infections based on parent-collected n
122                    Among children with acute respiratory tract infections, broad-spectrum antibiotics
123         Dementia increases the risk of lower respiratory tract infection, but it is unclear whether r
124               Early-life wheezing-associated respiratory tract infection by rhinovirus (RV) is a risk
125                             While most viral respiratory tract infections can be diagnosed clinically
126 ntification of the causative agents of lower respiratory tract infections can promote better patient
127       Coronavirus disease 2019 (COVID-19), a respiratory tract infection caused by a novel human coro
128  inflammation is a critical feature of lower respiratory tract infections caused by viruses such as r
129 ied a child with life-threatening, recurrent respiratory tract infections, caused by viruses includin
130 , stinging insects, fungi, pollutants, viral respiratory tract infections, climate change, and microb
131 60 yr) patients in health and during a lower respiratory tract infection, community-acquired pneumoni
132                                        Lower respiratory tract infection contributed to 174 (57%) of
133 me comprising a range of potentially serious respiratory tract infections, contributes to mortality i
134 5%] had bronchitis, 34 [12%] had viral upper respiratory tract infections), cough (34 [12%]), and dia
135    The most frequent AEs were fatigue, upper respiratory tract infection, cough, and dyspnea.
136 ice with TP73 deficiency suffer from chronic respiratory tract infections due to profound defects in
137 strongest manifest increased risk for severe respiratory tract infections during infancy and subseque
138 9% women) for antibiotic-inappropriate acute respiratory tract infections during the baseline period
139 ation study and subsequent symptoms of lower respiratory tract infections during the first year of li
140  pyrexia (eight [73%] of 11 patients), upper respiratory tract infection (eight [73%]), craniosynosto
141 HBoV1 is pathogenic to humans, causing acute respiratory tract infections, especially in young childr
142 lated from nasal lavage fluid during a viral respiratory tract infection expressed CysLTR1.
143                         Mortality from lower respiratory tract infection fell as cognitive ability in
144 eight [8%] patients in each group) and upper respiratory tract infections (five [5%] patients in each
145               Virus-associated febrile lower respiratory tract infections (fLRIs) during infancy have
146                                        Lower respiratory tract infections from respiratory syncytial
147  Adverse events were manageable and included respiratory tract infections, gastrointestinal symptoms,
148 st frequently reported on-treatment AEs were respiratory tract infection, headache, bronchitis, and a
149 ween neonatal interferon responses and lower respiratory tract infection history during infancy, whee
150 ] women), clinical presentation was an upper respiratory tract infection in 12 (67%), and viral shedd
151 ects of oral corticosteroids for acute lower respiratory tract infection in adults without asthma.
152 ruses (RVs) are a major cause of symptomatic respiratory tract infection in all age groups.
153      Parainfluenza virus (PIV) is a cause of respiratory tract infection in children and the immunoco
154 rus (hMPV) is a leading cause of viral lower respiratory tract infection in children.
155 ocavirus (HBoV) 1 can cause life-threatening respiratory tract infection in children.
156 d, although hMPV is a leading cause of lower respiratory tract infection in children.
157 b for the prevention of RSV-associated lower respiratory tract infection in healthy infants who had b
158 re present during symptoms of an acute viral respiratory tract infection in human subjects.
159 ion is a leading cause of severe acute lower respiratory tract infection in infants and children worl
160 RSV and hMPV are the leading causes of acute respiratory tract infection in infants and children.
161  virus (RSV) is a significant cause of lower respiratory tract infection in infants and elderly.
162 the most prevalent worldwide cause of severe respiratory tract infection in infants and young childre
163 l virus (RSV) is the leading cause of severe respiratory tract infection in infants and young childre
164  RSV-associated, medically significant lower respiratory tract infection in infants up to 90 days of
165 irus (RSV) is the most common cause of lower respiratory tract infection in infants, and a need exist
166  syncytial virus (RSV) is a leading cause of respiratory tract infection in infants, causing signific
167 rus (hRSV) is a leading cause of acute lower respiratory tract infection in infants, elderly and immu
168  (RSV) is the dominant cause of severe lower respiratory tract infection in infants, with the most se
169 us (RSV) is the most frequent cause of lower respiratory tract infection in infants.
170 efficiently inhibits established acute lower respiratory tract infection in the animals, even when tr
171 irmed COVID-19 adults with symptoms of lower respiratory tract infection in the emergency department
172 the pitavastatin group (n=12, 10%) and upper respiratory tract infection in the pravastatin group (n=
173 tial virus (RSV) is a leading cause of lower respiratory tract infection in young children worldwide.
174 cytial virus is a major cause of acute lower respiratory tract infection in young children, immunocom
175 -level proportion of prescriptions for upper respiratory tract infections in 2-14-year-old outpatient
176  cause of acute otitis media in children and respiratory tract infections in adults with chronic obst
177 RSV) is the leading etiologic agent of lower respiratory tract infections in children, but no license
178 rrow-spectrum antibiotic treatment for acute respiratory tract infections in children.
179  (hRSV) is the leading cause of severe lower respiratory tract infections in children.
180                          Coronaviruses cause respiratory tract infections in humans and outbreaks of
181 nts.IMPORTANCE Influenza viruses cause upper respiratory tract infections in humans.
182 served in vivo and the occurrence of chronic respiratory tract infections in immunocompromised hosts.
183 he most common viruses associated with acute respiratory tract infections in infancy.
184 al virus (RSV) is the leading cause of lower respiratory tract infections in infants, a safe and effe
185 (RSV) is a major cause of severe acute lower respiratory tract infections in infants.
186 yncytial virus (RSV) is the primary cause of respiratory tract infections in infants; however, curren
187 al virus (RSV) is the leading cause of lower respiratory tract infections in the very young.
188 biotic use in patients with non-severe acute respiratory tract infections in Vietnam.
189        RSV is a major cause of serious lower respiratory tract infections in young children and cause
190                           HBoV1 causes acute respiratory tract infections in young children and has a
191 e of the significant pathogens causing acute respiratory tract infections in young children worldwide
192 emerging respiratory virus that causes lower respiratory tract infections in young children worldwide
193 rus of the Parvoviridae family, causes acute respiratory tract infections in young children.
194 oV1) is a human parvovirus that causes acute respiratory tract infections in young children.
195 BoV1) is pathogenic to humans, causing acute respiratory tract infections in young children.
196 on reduces the incidence of wintertime upper respiratory tract infections in young children.
197  1 (HBoV1), a human parvovirus, causes lower respiratory tract infections in young children.
198 ytial virus (RSV) is the main cause of lower respiratory tract infections in young children.
199  a major causative agent of upper- and lower-respiratory-tract infections in infants, the elderly, an
200 en and is the leading cause of serious lower-respiratory-tract infections in young children.
201 ild diarrhea (in 52% of the patients), upper respiratory tract infection (in 48%), nausea (in 47%), a
202   Common grade 1-2 toxicities included upper respiratory tract infections (in 28 [57%] of 49 patients
203  of the respiratory tract during viral upper respiratory tract infection, in addition to the relation
204                          Multiplex tests for respiratory tract infections include up to 20 targets fo
205 risk of respiratory morbidity from recurrent respiratory tract infections including those from respir
206                                        Lower respiratory tract infections, including hospital-acquire
207                                        Viral respiratory tract infections increase the risk of develo
208 thelial secretome participating in RSV lower respiratory tract infection-induced airway remodeling.
209 DARA-MD 1200 mg were thrombocytopenia, upper respiratory tract infection, insomnia, and decreased app
210 s pneumoniae, the transition to severe lower respiratory tract infection is associated with an increa
211                                  Acute lower respiratory tract infection is common and often treated
212      Respiratory syncytial virus (RSV) lower respiratory tract infection is implicated in asthma deve
213 g for viruses in children who present with a respiratory tract infection is to differentiate between
214       Inappropriate antibiotic use for acute respiratory tract infections is common in primary health
215 ad-spectrum antibiotic prescribing for acute respiratory tract infections is increasing.
216 body deficiencies (PADs) experience frequent respiratory tract infections, leading to chronic pulmona
217 nical trial of the FDA-cleared Unyvero lower respiratory tract infection (LRTI) application (Curetis)
218                                        Lower respiratory tract infection (LRTI) commonly causes hospi
219 ith respiratory failure (RF) and fatal lower respiratory tract infection (LRTI) in premature children
220 evious pulmonary tuberculosis (PTB) or lower respiratory tract infection (LRTI) was significantly ass
221 iratory tract infection (URTI) without lower respiratory tract infection (LRTI), URTI progressing to
222  common reason for hospitalization was lower respiratory tract infection (LRTI).
223 nificance remains unclear in pediatric lower respiratory tract infection (LRTI).
224 I), urinary tract infection (UTI), and lower respiratory tract infection (LRTI).
225 5.84 (95% CI 5.61-6.08; p < 0.001) for lower respiratory tract infection (LRTI).
226 nfirmed hospitalizations or outpatient lower respiratory tract infection (LRTI).
227                                        Lower respiratory tract infections (LRTIs) are a leading cause
228                              Childhood lower respiratory tract infections (LRTIs) cause substantial m
229 l pathogen in hospitalized adults with lower respiratory tract infections (LRTIs).
230  growth of pathogens potentially relevant to respiratory tract infection may be triggered by changes
231               Pneumonia (n=5 [5%]) and lower respiratory tract infection (n=4 [4%]) were considered t
232 ost common serious adverse events were lower respiratory tract infection (n=7 [7%]), pneumonia (n=7 [
233                  In contrast, non-CAAP lower respiratory tract infections (NA-LRI) are generally not
234                  In contrast, non-CAAP lower respiratory tract infections (NA-LRIs) are generally not
235 y their child exhibited symptoms of an upper respiratory tract infection or asthma exacerbation (epis
236 /3IFNs, whereas risk for infant wheezy lower respiratory tract infections or "transient early wheeze"
237 eated with intravenous ceftriaxone for lower respiratory tract infections, oral ribaxamase reduced th
238     Eighteen (86%) patients were treated for respiratory tract infections; others were treated for bl
239 irus (CMV) antigenemia (p = 0.005) and lower respiratory tract infection (p = 0.003) and no leucopeni
240 he mean number of laboratory-confirmed upper respiratory tract infections per child was 1.05 (95% CI,
241 Subject Headings terms: "acute bronchitis," "respiratory tract infection," "pharyngitis," "rhinosinus
242 considering prevention or treatment of viral respiratory tract infections, potential targets include
243 ypically young children with upper and lower respiratory tract infection, presenting with symptoms in
244                        Anemia (33.3%), upper respiratory tract infection, pyrexia, and diarrhea (26.7
245 atracheal routes to cause an upper and lower respiratory tract infection, respectively.
246 elop respiratory syncytial virus acute lower respiratory tract infection.Respiratory syncytial virus
247  syncytial virus (RSV) is a leading cause of respiratory tract infection (RTI) in young children.
248                            Consultations for respiratory tract infection (RTI), skin or urinary tract
249     The clinical signs and symptoms of acute respiratory tract infections (RTIs) are not pathogen spe
250 urden of severe human metapneumovirus (HMPV) respiratory tract infections (RTIs) in European children
251 urden of human coronavirus (HCoV)-associated respiratory tract infections (RTIs) in hospitalized chil
252 ota stability and thereby resistance against respiratory tract infections (RTIs) over time.
253 s in the prospective cohort, 21 distinct BoV respiratory tract infections (RTIs) were observed by 1 y
254  mediator in the susceptibility to childhood respiratory tract infections (RTIs).
255 fection rates, and identify risk factors for respiratory tract infections (RTIs).
256 in uncomplicated urinary and upper and lower respiratory tract infections (RTIs).
257 ct microbiota are related to pathogenesis of respiratory tract infections (RTIs).
258 ized adults varies widely and includes upper respiratory tract infections, severe lower respiratory t
259  immunodeficiency characterized by recurrent respiratory tract infections, susceptibility to herpesvi
260 osteroids should not be used for acute lower respiratory tract infection symptoms in adults without a
261 or duration or severity of other acute lower respiratory tract infection symptoms, duration of abnorm
262 es were duration and severity of acute lower respiratory tract infection symptoms, duration of abnorm
263                              Atopy and viral respiratory tract infections synergistically promote ast
264 vents in both groups were headache and upper respiratory tract infection (ten [16%] for both events i
265  respiratory tract infection to severe lower respiratory tract infection, that can lead to diffuse al
266 ted with intravenous ceftriaxone for a lower respiratory tract infection, thereby supporting continue
267 act animals demonstrated various symptoms of respiratory tract infection, they were mild, and the cal
268 ral, bacterial, or fungal pathogens, such as respiratory tract infections, this necessitates large pa
269  was medically attended RSV-associated lower respiratory tract infection through 150 days after admin
270 was hospitalization for RSV-associated lower respiratory tract infection through 150 days after admin
271 pectrum of diseases, ranging from mild upper respiratory tract infection to severe lower respiratory
272  RSV-associated, medically significant lower respiratory tract infection up to 90 days of life, and t
273 s completed daily from the onset of an upper respiratory tract infection (URTI) until asthma symptom
274 e grouped according to the presence of upper respiratory tract infection (URTI) without lower respira
275 t paediatric diarrhoea and adult acute upper respiratory tract infection (URTI), which were presented
276 There are no antivirals to treat viral upper respiratory tract infection (URTI).
277 (QoL) assessments and the incidence of upper respiratory tract infection (URTI).
278                                        Upper respiratory tract infections (URTIs) are important trigg
279  Chinese primary care to children with upper respiratory tract infections (URTIs), we developed an in
280  RSV-associated, medically significant lower respiratory tract infection was 1.5% in the vaccine grou
281 e of medically attended RSV-associated lower respiratory tract infection was 70.1% lower (95% confide
282  of hospitalization for RSV-associated lower respiratory tract infection was 78.4% lower (95% CI, 51.
283           One treatment-related death from a respiratory tract infection was reported in the docetaxe
284 sLTR1 signaling in the first days of a viral respiratory tract infection was sufficient to reduce acc
285                                        Upper respiratory tract infection was the most frequent treatm
286 for hospitalization for RSV-associated lower respiratory tract infection were 2.1% and 3.7% (vaccine
287  one focal and one systemic symptom of acute respiratory tract infection were assigned 1:1 to receive
288                   Patients with severe acute respiratory tract infection were excluded.
289 enting with acute cough (for </=28 days) and respiratory tract infection were recruited to a prognost
290                                              Respiratory tract infections were most common and were d
291  breakthrough in the field of multimicrobial respiratory tract infections, wherein control of inflamm
292 pansion of CD8(+) T cells following an upper respiratory tract infection with a pathogenic influenza
293 had been admitted to a hospital with a lower respiratory tract infection with a pneumonia index score
294 dex was found to be a robust marker of viral respiratory tract infection with a sensitivity of 80% an
295 ponding percentages for RSV-associated lower respiratory tract infection with severe hypoxemia were 0
296  the performance of BN in infants with acute respiratory tract infections with different degrees of d
297       The outcome was hospital admission for respiratory tract infection within 30 days, collected us
298  reduced antibiotic use for non-severe acute respiratory tract infection without compromising patient
299 ibing rates when diagnostics suggested viral respiratory tract infection, without a higher rate for r
300 ibing rates when diagnostics suggested viral respiratory tract infection, without a higher rate for r

 
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