ライフサイエンスコーパス: response

1 cyte adherence, and activation of the immune response.

2 cular bed is crucial for an effective immune response.

3 bility and the ability to tailor its dynamic response.

4 y associated with the induction of an immune response.

5 promoted the acquisition of an instrumental response.

6 ween cell envelope homeostasis and stringent response.

7 RLK1L) and others involved in abiotic stress response.

8 ory studies identify potential biomarkers of response.

9 ironment that vary by subtype and pathologic response.

10 can operate to create an ultrasensitive dose response.

11 e conventional pharmacodynamic biomarkers of response.

12 lecular imaging agents for endocrine therapy response.

13 tion to a highly cooperative flagellar motor response.

14 o dictate cancer progression and therapeutic response.

15 ransmission, vectorial competence and immune response.

16 broadly protective CD4(+) and CD8(+) T cell responses.

17 nd the induction of protective CD8(+) T cell responses.

18 d therapeutically targetable regulator of GC responses.

19 lus history to odor sensation and behavioral responses.

20 nd stable responses, in addition to adapting responses.

21 gate the B-cell compartment and evade immune responses.

22 suppressed Ag-specific humoral and cellular responses.

23 es, leading to detrimental effects on immune responses.

24 r of Nrf2 signaling-dampens these protective responses.

25 esult in deleterious pro-inflammatory immune responses.

26 tions corroborate the observed physiological responses.

27 ssing exosomes can inhibit antitumour immune responses.

28 ry (Tfr) cells that regulate germinal center responses.

29 vector to induce HBV-specific B- and T-cell responses.

30 ate ionizing radiation-induced innate immune responses.

31 mune responses and adaptive cytotoxic T cell responses.

32 nses correlated with spike-specific antibody responses.

33 me shifts and enhanced intestinal CD8 T cell responses.

34 lysosomal injury, Gal3 controlled autophagic responses.

35 ype-B Response Regulator family of cytokinin response activators.

36 d a remarkable increase of functional immune responses against GBS compared to the simple co-administ

37 for inducing effective cytotoxic and humoral responses against pathogens.

38 Neutralising antibody responses against SARS-CoV-2 were detected in 32 (91%) o

39 y plotting the measured ratios of the MS ion responses against the known spiked-in ratios (CVs < 8% f

40 nal through the MAVS adaptor to activate IFN responses against viruses.

41 ution, including dampening of the T helper 1 response, alternative activation of macrophages, efferoc

42 The diversity of responses among species highlights the necessity to asse

43 Vitamin A regulates the adaptive immune response and a modulatory impact on type I allergy is di

44 dysregulation indicative of an inflammatory response and cellular function deficits.

45 mpacts of minority HIV variants on virologic response and clinical outcome.

46 elevant tumour behaviours, such as treatment response and emergence of drug resistance: inference bas

47 ormed to investigate potential biomarkers of response and resistance.

48 n intestinal epithelial cells in the colitis response and shows how a highly conserved chromatin remo

49 is unclear, as are potassium's role in this response and the receptor's effect on intercalated and p

50 er immunotherapy to further improve clinical response and toxicity profiles has grown.

51 al-grade assays developed to predict patient response and, ultimately, to help select those most like

52 must evade both intracellular innate immune responses and adaptive cytotoxic T cell responses.

53 viewing real-world images, and found visual responses and category selectivity consistent with previ

54 d elements enables differentiated mechanical responses and consistently enables and extends functiona

55 organs and consequent excessive inflammatory responses and endothelial damage.

56 The ability to rapidly predict SaB patient responses and guide personalized treatment regimens coul

57 Single-drug oral selinexor induced durable responses and had a manageable adverse events profile in

58 ping to study the strength of LH optogenetic responses and network oscillations, which were consisten

59 anging from cellular communication to immune responses and the protein-driven mineralization of bone.

60 associated with cell adhesion, inflammatory response, and extracellular exosome.

61 day 85), 29% of the patients had a molecular response, and this percentage increased to 60% after two

62 proteins enables fast actions, supra-linear responses, and long-lasting molecular switches.

63 thromboinflammation, dysregulation of immune responses, and maladaptation of ACE2-related pathways mi

64 een adjacent stages of processing in autism: responses are attenuated in a primary visual area but am

65 However, these responses are diminished after postnatal day-6 (P6), rep

66 These responses are nucleated via the AKAP5-dependent clusteri

67 These responses are preferentially reduced by anaesthesia and

68 /6 depletion triggers a CHEK2-p53 DNA damage response, as concomitant deletion of the Trp53 tumor sup

69 both promoters and targets of the autoimmune response, as well as discussing the mechanistic and ther

70 18 fluorodeoxyglucose PET/MRI for treatment response assessment in children and young adults.

71 ht of 72 patients were evaluable for a first response assessment with both PET- and CT-based criteria

72 Sustained virological response at 12 weeks post-treatment (SVR12) was the prim

73 I}, -11.9% to 1.2%]), and favorable clinical response at early follow-up was 61.0% and 55.8%, respect

74 lege of Rheumatology 20% improvement (ACR20) response at week 24 in all patients per assigned treatme

75 measure the frequency of EBV-specific T-cell responses between groups following stimulation with an E

76 See also the response by Yin et al. (2020), published in this issue.

77 ions that blunt productive anti-tumor immune responses by directly or indirectly excluding effector C

78 C voltammetry, the intensity of the Faradaic response can be enhanced at low frequencies (1 Hz) or ma

79 l size within 3 h, and the systemic stomatal response can be retriggered within 6 h.

80 Neutralising antibody responses correlated strongly with antibody levels measu

81 Total and spike-specific T cell responses correlated with spike-specific antibody respon

82 Our analysis shows that the dose-response curve with the FSS data clearly differs from th

83 Dose response curves of ML385, an NRF2 inhibitor, showed that

84 r22a and Or35a) showed a shift in their dose-response curves when Orco was co-integrated, reflecting

85 rporating parameters from rapid fluorescence response curves.

86 base excision repair and ATR-Chk1 DNA damage response (DDR) pathways, it remains unknown how the APE2

87 The thermal challenge response (DeltaSBF/DeltaT) was calculated using the foll

88 eys, tree diversity noticeably affected bird responses, demonstrated by significantly higher abundanc

89 ual variability in weight loss and metabolic responses depends upon interactions between genetic, phe

90 ch convergence enables stereotypy in sensory responses despite random connectivity.

91 macrophages, showed that the transcriptional response downstream of TLR4 was intact in cells lacking

92 S3 within EVs serves as a brake on airway EC responses during allergic inflammation, but is impaired

93 es converge on the transcription factor cAMP response element-binding protein (CREB) to enhance the e

94 n be temporarily rescued by the inflammatory response elicited by the administration of lipopolysacch

95 are critical for the expression of defensive responses elicited by conditioned threats.

96 ent age on their GABA(A) receptor (GABA(A)R) responses, elicited by muscimol.

97 and 31% and 52% of genes with cis-eQTLs have response eQTLs (reQTLs) in myeloid cells and T cells, re

98 G showed that learning augments the muscular response evoked by motoneuron output and that this effec

99 IAA)-histone deacetylase (HDA) and (2) auxin response factor (ARF)-histone acetyltransferase (HAT).

100 production to promote an altered Th2 immune response following RSV infection that leads to more seve

101 nflammatory, prothrombotic, and procoagulant responses following severe acute respiratory syndrome-co

102 treatment induced a similar early metabolic response for both WT-ER and Y537S-ER tumors.

103 A declining first-phase insulin response (FPIR) is associated with positivity for multip

104 Responses from 347 of 808 eligible first- and second-yea

105 Color contrast response functions were measured in two experiments with

106 relatively little about individual and group responses given the rarity of observed predation events.

107 isorders, objectively measured physiological responses have commonly been used as a proxy for measuri

108 of action potentials, we found that calcium responses have the capacity to encode action potential f

109 hat lack rapid testing of the patient immune response, impeding clinicians from providing appropriate

110 The electronic Seebeck response in a conductor involves the energy-dependent me

111 e found that visual speech evokes a positive response in the human posterior superior temporal gyrus,

112 d of patients have a pathologically complete response in the resection specimen.

113 role of betaCA3 in the high CO(2) -mediated response in tomato and two other Solanaceae crops is dis

114 lerated and can induce a sustained antiviral response in WHV-infected woodchucks; the identification

115 We analyzed immune responses in 76 COVID-19 patients and 69 healthy individ

116 In addition to neutralizing IgG antibody responses in a protective range, multifunctional CD8(+)

117 induced activating versus suppressive immune responses in affording protection from HIV.IMPORTANCE CD

118 ntioxidants, to facilitate enhanced cytokine responses in HIEs.

119 e rates of UTIs, we examined adaptive immune responses in mouse bladders.

120 d provided clinically meaningful and durable responses in patients with mUC; survival data are encour

121 lop bronchopneumonia and strong inflammatory responses in the lungs with neutrophil infiltration and

122 ly contributes to flexible control of threat responses in unpredictable environments.

123 cortex (A1) exhibit facilitating and stable responses, in addition to adapting responses.

124 the percentage of patients with a molecular response increased further after additional blinatumomab

125 peripherally restricted, affect brain oxygen responses induced by intravenous heroin at low, human-re

126 n underlying adaptive codon-based regulatory response inherent to the genetic code.

127 noma, the biological features of the durable responses initiated by these drugs remain unknown.

128 The bladder epithelial repair response is cumulative and aberrant as, after multiple i

129 ere, we tested the hypothesis that the S-OFF response is mediated by the S-ON pathway through inhibit

130 easing Atlantic influence, but the eukaryote response is more complex.

131 i into biochemical signals and physiological responses is still limited.

132 ough soil structure affects local hydrologic response, its implications on global-scale climate remai

133 we report that inhibitors of the DNA damage response kinase ATR can significantly potentiate ionizin

134 components involved in multifaceted disease responses, like atherosclerosis.

135 daunorubicin activated an integrated stress response-like transcriptional program to induce ABCB1 th

136 hway to demonstrate dissociation in the fMRI response magnitude between adjacent stages of processing

137 In response, many diagnostic manufacturers have developed m

138 In response, marine resource managers in many locations hav

139 The responses measured were an increase in the intracellular

140 stress, and dysregulation of these adaptive-response mechanisms underlies the development of myeloid

141 Random effects dose-response meta-analyses were used to estimate summary rel

142 ance of blood homeostasis requires a dynamic response of HSCs to stress, and dysregulation of these a

143 The response of mangroves to high rates of relative sea leve

144 w mechanistic insights on the selective poor response of SCC-TAFs to nintedanib.

145 molecular underpinnings of the innate immune response of the larvae to the pathogen.

146 In vitro and in vivo growth responses of Abi-/Enza-resistant LNCaP-95 cells in which

147 This variation influences flowering responses of Arabidopsis accessions resulting in an inte

148 y have relevance to our understanding of the responses of ecologically important organisms to changin

149 While several ATP analogues gave responses of similar magnitude to ATP, including the pre

150 Simultaneously, negative responses of winter survival and reproductive-status cha

151 rous chromosomal alterations associated with response or resistance to PD-1 blockade.

152 nesis, innate viral control, adaptive immune responses or the balance of inflammation and tissue repa

153 elation with cell adhesion molecules and IFN response pathways and a strong negative correlation with

154 re correlated with the pathological complete response (pCR).

155 inding with contrast-reversing gratings that response phase advances with grating spatial phase.

156 previously described that tailoring the rate-response programming of cardiac implantable electronic d

157 own activities but also to trigger critical responses promoting homeostasis in its host.

158 ated that increased expression of the stress response protein regulated in development and DNA damage

159 motherapy did not improve major pathological response rate (TRG1 = 8%) but was associated with a sign

160 Objective response rate and progression-free survival per investig

161 owing season of treatment, the shrub warming response rate increased to 2.54 km m(-2) degrees C(-1) S

162 median follow-up of 12 months, the objective response rate to ipilimumab and nivolumab was 20%.

163 The RECIST-defined radiological response rate was lower than that frequently quoted to p

164 year adult nephrology fellows were examined (response rate=42.9%).

165 RCB-0 (pathologic complete response) rate was 53% and RCB-0/I was 63%.

166 rst cycle had significantly higher objective response rates and longer progression-free and overall s

167 Response rates were 41.7% in the active group and 36.4%

168 45 surgeons (10 countries), the second-round response rates were 61% and 85% respectively, with ten o

169 llow-up was 59 months, and overall and major response rates were 90.5% and 79.4%, respectively.

170 R0 and pathologic complete response rates were 96% and 62%, respectively.

171 PD-L1 expression (n = 28/40 evaluable), and response rates were higher in PD-L1-positive (8/28; 29%)

172 tivation of proteins belonging to the type-B Response Regulator family of cytokinin response activato

173 Innate immune responses rely on rapid and precise gene regulation medi

174 one methylation dynamics during inflammatory responses remain enigmatic.

175 capable to provide an assessment of both the response reproducibility, by enabling measurement in tri

176 el of TCR signaling in which multiple T cell responses share a common rate-limiting threshold and a c

177 In response, some tools have been augmented with spaced see

178 e and affinity do not provide any additional response-specific information.

179 Oncology, Oncology, Treatment Effects, Tumor Response Supplemental material is available for this art

180 The systemic inflammatory response syndrome (SIRS) frequently occurs in patients w

181 variceal bleeding; R: systemic inflammatory response syndrome (SIRS), spontaneous bacteria peritonit

182 invasive biomarkers for monitoring treatment response, tests for quantifying the "net state of immuno

183 ses and produced higher levels of interferon responses than were seen with wild-type icPEDV infection

184 e to attenuate an overly robust inflammatory response that is detrimental to the host during CDI.

185 activate an attenuated telomeric DNA damage response that lacks accompanying telomere fusions, and p

186 ive immunity and amplifies the type 2 immune response that may favor the development of cryptococcal

187 ma (PDAC) is characterized by a desmoplastic response that promotes hypovascularity, immunosuppressio

188 , and contribute to tissue-specific cytokine responses that are protective against mortality during e

189 s also are involved in non-nicotine-mediated responses that may predispose to addiction-related behav

190 essing efflux pumps are similar (impaired QS response), the underlying mechanisms are different.

191 r CaMKII in neuronal TRPV4-associated Ca(2+) responses, the importance of tightly regulated Ca(2+) dy

192 nt (visual) size does not cross their prey's response threshold until after rapid jaw expansion.

193 (2)O(3) and other existing materials lack in response time and stability at elevated temperatures.

194 biosensor for lactate detection which had a response time of less than 10 s over the range of 0.05-1

195 ce exhibits a high proton conductivity, fast response time, and extremely large on/off ratio upon vis

196 gets in a visual search task while recording response times (RTs) and event-related potentials, focus

197 expression of many transcription factors in response to 5,8-diHODE.

198 In response to a longstanding Federal mandate to minimize t

199 oth terminal domains, and characterize their response to a number of biomimetic spinning triggers.

200 n the heat and carbon uptake of the ocean in response to anthropogenic emissions.

201 Ocn-Cre(+) dDG neurons were highly active in response to anxiogenic environment but had lower excitab

202 of a phosphate group onto another protein in response to appropriate regulatory cues.

203 f methods to quickly quantify the pathogen's response to beta-lactams.

204 Brain changes in response to binge EtOH treatment were more pronounced in

205 mble filamentous polymers in cells, often in response to changes in physiological conditions.

206 reading processes, pathogens often evolve in response to changing environments and medical interventi

207 the recent work examining animal movement in response to changing phenology from migratory birds and

208 ectable cholangiocarcinoma (CCA) is its poor response to chemotherapy, which is partly due to reducti

209 astrocyte-mediated synaptogenic mechanism in response to cocaine experience and embed critical cue-as

210 the brain's initial molecular and epigenetic response to cocaine.

211 e metabolites that modulated the hypothermic response to CR.

212 influenced richness and diversity, likely in response to differences in soil properties.

213 innate immune defence that are activated in response to diverse stimuli, including pathogen-associat

214 Nocturnal mosquitoes exhibit a behavioral response to divert away from surfaces when vision is una

215 the importance of root exudates in ecosystem response to drought.

216 evels of IRE1alpha and IGFBPs predict a poor response to drugs inducing unresolvable UPR and possibly

217 production revealed differential patterns in response to each inhibitor.

218 l annotations of this core set center around response to energy crisis and renewal of energy resource

219 on the genetic basis of resting Tpe and Tpe response to exercise and recovery, unveiling plausible c

220 ongitudinal changes in retinal blood flow in response to flicker stimulation and systemic hyperoxia i

221 he "shrubification" of northern peatlands in response to global change.

222 ic transcriptional signature associated with response to GS-9688 treatment provides insights into the

223 nables cytoplasmic chromatin recognition and response to immune checkpoint blockade.

224 utation develops and whether it predicts the response to immunotherapy are poorly understood.

225 g desmin or vimentin generated less force in response to KCl and carbachol relative to the levels in

226 cilitate protein secretion in macrophages in response to LPS.

227 jury in RVD patients, but does not change in response to medical or interventional therapy over 3 mon

228 terferon Genes) mediates protective cellular response to microbial infection and tissue damage, but i

229 netics and selectivity of gene activation in response to microbial ligands; however, these studies do

230 y to higher rates of litter decomposition in response to N deposition.

231 emission tomography (PET) as a predictor of response to naltrexone.

232 regulates protein synthesis during cellular response to oxidative stress.

233 robustness and which anticipates an embryo's response to perturbations in lineage composition.

234 ransport of bacteria within a leaf tissue in response to photosynthesis occurring within plant mesoph

235 using the proposed technique delivers sensor response to raw fish within 4 min, reflecting its freshn

236 lls are mobilized from bone marrow niches in response to remote ischemic injury and migrate to the ar

237 d multi-unit activity (MUA) in the cortex in response to repeated brief optogenetic stimulation of th

238 We first show that in response to repeated tones pyramidal (Pyr) neurons in ma

239 h increasing frequency as the globe warms in response to rising concentrations of greenhouse gases.

240 utrophils are critical for the innate immune response to S. aureus infection.

241 phorylation (Ser73), and AP-1/DNA-binding in response to S. mansoni infection.

242 Regenerative response to skeletal muscle injury in Speg-KO mice was c

243 mans linked to individual differences in the response to stress.

244 differential regulation of 12-OPDA and JA in response to T. virens colonization results in ISR induct

245 e seeded with cell-laden collagen, which, in response to the gradual slope of the circumferential ram

246 in the imaging of bone metastases and their response to therapy have led to adoption of some of thes

247 ardized uptake value (SUV) metrics to assess response to therapy, and we optimized a preclinical PERC

248 nalysis, which is critical for a data-driven response to this public health challenge.

249 st that assessing the proinflammatory immune response to trauma exposure immediately after trauma exp

250 s needed to understand how to monitor immune response to vaccines in immunosuppressed patients and wh

251 affects ammonium and nitrate assimilation in response to various nitrogen sources.

252 beta is a key component of the innate immune response to viral infection.

253 a master regulator of energy metabolism, in response to ZIKV challenge.

254 et binding is a major predictor of bacterial responses to antibiotics.

255 Lyz1-deficiency diminished intestinal immune responses to bacterial molecular patterns and resulted i

256 We assessed endogenous proteomic responses to cysteine limitation in Mycobacterium smegma

257 We tuned responses to different wavelengths, by using nanorods of

258 rstand how tree size and traits shape growth responses to droughts.

259 ly related plant species show more divergent responses to each other's soil microbiota compared with

260 Adaptive responses to ecological uncertainty may affect the dynam

261 or their vegetative growth and physiological responses to four different water regimes: 100% (control

262 M.tb infection and BCG vaccination on B cell responses to heterologous pathogen recall antigens.

263 tein with diminished abilities to block host responses to infection.

264 ll-cell signaling in homeostatic health, the responses to injury, and new methods to study lung repai

265 Acute cardiorespiratory responses to O(2) deficiency are essential for physiolog

266 zed an intriguing mechanism that enhances V1 responses to perceptual figures, we have a poor understa

267 These findings suggest that root responses to precipitation change may critically influen

268 on of the PFC-BNST pathway restored abnormal responses to predator odor in alcohol-exposed mice.

269 hashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease pr

270 ns orchestrate cardiorespiratory and arousal responses to somatic stresses, whereas RTN selectively c

271 eneity in phenotype trends indicates complex responses to spatiotemporal environmental gradients pote

272 , we constructed four scenarios for possible responses to the COVID-19 pandemic: no action, mitigatio

273 munization provides a method to focus immune responses to the desired target region, in the absence o

274 ether CCL2 or IL12 define effective monocyte responses to the parasite.

275 ing pathways is essential for fine-tuning of responses to the prevailing environmental conditions.

276 al trials in breast cancer have reported low responses to these therapies.

277 ted patients, highlighting stereotyped naive responses to this virus.

278 ative, population-level averages of monocyte responses to Toxoplasma have sometimes produced contradi

279 ction, CD40L has been used to enhance immune responses to vaccines, including candidate vaccines for

280 We observe here increased responses to vasoconstrictors in arteries from Jak2V617F

281 nonparametric approach in which group-level response trends for logarithmically scaled tumor volume

282 eatic cancer cells enhanced unfolded protein response (UPR) signaling and cell death upon ER stress i

283 er immunotherapies enhance anti-tumor immune responses using checkpoint inhibitors, such as PD-1 or P

284 changes in BW, BF%, and metabolic markers as response variables.

285 tiviral defense, influencing adaptive immune responses via interactions with dendritic cells (DCs).

286 Among 45 responders, the median duration of response was 8.0 months (95% CI 6.5-14.7).

287 An independent reviewer-assessed overall response was achieved by 20 (47%, 95% CI 31-62) of 43 pa

288 The response was eliminated by a 2-ns bipolar pulse with pos

289 This response was impaired when the minimum EBE was fused wit

290 In response, we directly test the original methods in a mul

291 filtration were not associated with clinical response, we discovered numerous chromosomal alterations

292 nitiative study, and the analyses of 64 drug responses, we demonstrate that MKpLMM consistently outpe

293 cked visual cues in one environment, whereas responses were almost completely absent when the same cu

294 Responses were blocked by atropine or DAU 5884, but not

295 SARS-CoV-2-specific T cell responses were driven by TCR clusters shared between pat

296 Total memory T-cell responses were measured after anti-CD3 or vaccinia virus

297 No responses were observed with ATM or CHEK2 mutations alon

298 tude and fully restored (unipolar-equivalent response) when the delay between each phase of the bipol

299 ription factor is crucial for cytoprotective response, whereas Keap1-an endogenous inhibitor of Nrf2

300 ge, multifunctional CD8(+) and CD4(+) T cell responses with S protein-specific killing activity were