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1 ean absolute errors: 3.11 versus 2.35 DOTs), resulting in 31-33% more hospitals moving into bottom or
3 yclopentenes, derived from (+)-vince lactam, resulted in 5-exo cyclizations which furnished a series
4 nding, the use of systemic therapy alone can result in a castrate-resistant state; therefore, increas
6 ., followed from 2015 through to death), and result in a health-related net monetary benefit of pound
7 us change to declining environmental quality result in a higher risk of population quasi-extinction,
8 es at the transmembrane region of IrtAB that result in a partially collapsed inward-facing substrate-
9 imate change scenarios considered here could result in a potential loss of suitable habitat in Minnes
10 followed by the removal of the ion template, result in a wholly organic molecular material that forms
11 munosuppression in the recipients in the RGT resulted in a 12% BCAR rate (expected range 3.2-18.0).
12 Notably, only 14% of the boundary deletions resulted in a change in expression in nearby genes of mo
13 e RotaTeq vaccine were radical in nature and resulted in a change in polarity from a polar to non-pol
14 at position D195G was radical in nature and resulted in a change in polarity from a polar to non-pol
15 ine-an open channel blocker of HCNs-for 24 h resulted in a dose-dependent higher HRV and lower heart
16 f drug resistance in Helicobacter pylori has resulted in a greater need for susceptibility-guided tre
17 between local water flow and reef morphology resulted in a highly heterogenous physical environment e
18 ; however, in females, overexpression of CRF resulted in a larger increase in CRFr1 and CRFr2 relativ
23 an AAV8-ZAP-70 vector into ZAP-70(-/-) mice resulted in a rapid thymocyte differentiation associated
25 Applying the 8th edition staging criteria resulted in a stage change for >35% of patients diagnose
26 of 302 volunteers, early morning vaccination resulted in a superior cytokine production capacity comp
27 nsgenic mouse model, oncogene transformation resulted in a timely abrogation of miR-223 expression, l
28 lipid-induced stabilization to the channel, resulting in a 3D reconstruction at 1.9 angstrom resolut
30 l attention, and expanding economic activity resulting in a dramatic increase in shipping activity.
32 tion of monocarboxylate transporters (MCTs), resulting in a negative feedback on glycolytic rate.
33 anism is lost with acute irradiation injury, resulting in a paucity of tuft cells and acetylcholine p
35 patient age, 56 years; range, 25-94 years), resulting in a positive predictive value for biopsy of 4
36 17 was the result of higher physical demands resulting in a reduced demand for energy to thermoregula
37 ifferent gRNAs targeting HEK293 genomic DNA, resulting in a set of 55 high-confidence gRNA cleavage s
39 dy that binds across the E and prM proteins, resulting in a subnanometer resolution structure of caps
40 ind that every day ART initiation is delayed results in a 39% increase in the recrudescence rate (95%
45 that a gain-of-function JAK1 genetic variant results in a mutant protein with mosaic expression that
46 tified a single-nucleotide polymorphism that results in a premature stop in translation, yielding a t
47 informing real-time public health responses, resulting in accurate and prompt disease management and
49 ngoing coronavirus disease 2019 pandemic has resulted in additional challenges for systems designed t
52 t disabling of the PKS gene at fertilization resulted in albinism throughout all life stages and thro
53 rget for developmental endocrine disruption, resulting in altered neuroendocrine control of hormonal
54 d that the antibiotic resistance crisis will result in an annual death rate of 10 million people by t
55 less valuable (studies 9A and 9B), which may result in an imbalanced and inefficient provision of res
57 We found that stimulation at 1 Hz for 1 hr resulted in an almost complete suppression of spontaneou
60 tion of plasmanylethanolamine substrates and resulted in an inability of these cells to form labeled
62 ceptor properties of the formazanate ligand, resulting in an "inverted" ligand field, with an approxi
63 ation or de-escalation in 48.2% of patients, resulting in an average savings of 6.2 antibiotic days/p
65 se of a failure to learn sensory statistics, resulting in an impaired representation of the world.
66 mperature was the main driver of adaptation, resulting in an increased thermotolerance of the 30 degr
67 lowering responses of Arabidopsis accessions resulting in an interplay between promotion and delay of
71 murine models for Cornelia de Lange syndrome results in an inefficient and senescent placenta that im
73 ion of impalpha-1, impalpha-2 and impalpha-3 resulted in Arabidopsis plants with a rapid flowering ph
74 nditional knockout of Grp in sensory neurons results in attenuated non-histaminergic itch, without im
75 e symptoms in conjunction with standard care resulted in better functional outcomes at 90 days than s
78 r NAc findings, using published smoking EWAS results in blood, to identify DNAm smoking effects that
80 electron-lattice scattering are intertwined resulting in breaking of the Matthiessen's rule with inc
81 hown that germline deletion of Grb14 in mice results in cardiac hypertrophy and impaired systolic fun
83 antly as the replacement of forbs by grasses resulted in changes in relative abundance across trophic
85 tween B2 RNA and the Polycomb protein, EZH2, results in cleavage of B2 RNA, release of B2 RNA from ch
86 suppression using checkpoint inhibition has resulted in clinical responses in some patients with RCC
88 ion voltages in the interface of tandem-TIMS results in collision-induced dissociation (CID) of avidi
89 UC), is a disease associated with dysbiosis, resulting in compromised intestinal epithelial barrier a
90 mutational disruption of these interactions resulted in constitutively active proteins, freed from a
92 om passive and active IgE sensitization, and resulted in cross-protection against different allergens
94 on of HPCs with an HCMVDeltamiR-US5-2 mutant resulted in decreased TGF-beta expression and restoratio
96 gions of H3K18ac, and the depletion of DIGIT results in decreased recruitment of BRD3 to these region
97 antimicrobial susceptibility testing (AST), resulting in delayed therapeutic decisions at the point
98 BDG antigenaemia, in the absence of IFD, can result in deleterious pro-inflammatory immune responses.
100 stly, contractions at different times of day resulted in differential changes of core clock gene expr
101 ated conformational changes within RRS1 that results in distinct modes of derepression of the complex
106 , and the potential interventions that might result in efficient treatment of social-emotional disord
107 ckening and occlusion by neointimal lesions, resulting in elevated pulmonary vascular resistance and
109 etion of the pe/ppe genes in M. tuberculosis resulted in enhanced autophagy and improved intracellula
110 ment before AAV vector infusion was safe and resulted in enhanced liver transduction, even in the set
111 erein 5-AzadC induced DNA damage, which then resulted in enhanced occupancy of NF-kB, P-TEFb, and ser
112 tarch co-precipitation during RNA extraction resulted in enhanced yield and quality of RNA with RIN v
113 s and Mn(2+) for chemodynamic therapy (CDT), resulting in enhanced reactive oxygen species (ROS) gene
114 iciently increase cell membrane permeability resulting in enhanced tissue distribution and intracellu
115 the activating Fcgamma receptor FcgammaRIIa results in enhanced ability to prevent or treat lethal v
117 the gene encoding Slack (K(Na)1.1) channels, result in epilepsy of infancy with migrating focal seizu
123 rbations are inflammatory events that rarely result in full hospitalization following an ER visit.
124 siologic milieu and systemic regulation that resulted in functional and histological recovery after 2
126 e quiescence of tissue-resident macrophages, resulting in genetically programmed susceptibility to ba
128 ptal TMVI to treat failing bioprostheses may result in good short-term outcomes that allow uneventful
129 Infection with laboratory-adapted Mtb H37Rv resulted in granulomas that are characterized by unorgan
130 ls and their interactions differently as DTW results in greater daily temperature variation and moves
131 Because the combination of these actions results in Grp1 being recruited preferentially to the re
132 nts underwent an 8-wk low-calorie diet (LCD) resulting in >=8% body weight loss, during which changes
133 ation of FMT capsules in adults with obesity results in gut microbiota engraftment in most recipients
134 acterized by severely short telomeres, often resulting in hematopoietic stem cell failure in the most
135 only the features selected by the algorithm, resulted in high agreement with the gold standard based
137 rotubule-bound state by slowing ATP-binding, resulting in high-force production at both homotetramer
138 mg/kg (600 mg for flat-dosing), flat-dosing resulted in higher median AUC0-24h compared to the weigh
139 ce leaves increases carotenoid availability, resulting in higher lutein and beta-carotene absorption,
140 ogical fluids and a decrease in its activity results in higher bacterial load and exacerbated organ d
141 al colonization from patients with cirrhosis results in higher degrees of neuroinflammation and activ
142 ribution around the tips of lithium buds and results in homogeneous plating and stripping of lithium
143 meat preparations with added nitrate to rats resulted in hyperactivity reminiscent of human mania, al
146 fluenza virus infects a wide range of hosts, resulting in illnesses that vary from asymptomatic cases
147 to HEV network density and/or morphology can result in immune activation or, as recently implicated,
148 oriomeningitis virus (LCMV) clone 13 (CL13), result in immune dysfunction that predisposes the host t
149 rived regulatory T (Treg) cells (ie, FOXP3), resulting in impaired Treg function and autoimmunity.
151 anscriptional activity in skin microvessels, resulting in improved microvascular function, as assesse
152 of function of ANK or ENPP1 (reducing PP(i)) resulted in increased cementum formation, suggesting PP(
155 ro, knockdown of GPRC5B in human aortic SMCs resulted in increased IP-dependent cAMP production and c
156 show similar Ca(++)-induced differentiation, resulting in increased 5-hmC levels and reduced nestin e
157 ll surface protrusions and poor aggregation, resulting in increased dissemination of small clusters c
158 glycans on trophoblasts and chorionic villi, resulting in increased permeability of human placentas.
162 he repair of acetaldehyde-induced crosslinks results in increased mutation frequency and an altered m
163 eart regeneration, and that absence of runx1 results in increased myocardial survival and proliferati
164 the mosquitoes, whereas SAP2 overexpression results in increased resistance, probably owing to high-
167 s aberrant H3K9me3 spreading over bdH3K4me3, resulting in insufficient transcriptional activation of
168 over, first-time magnetocaloric measurements resulted in irreproducible entropy change versus tempera
169 treatment of IEC organoids with type III IFN results in ISG expression that mirrors the in vivo type
172 s to either hemisphere are equally likely to result in language deficits, suggesting that language is
173 Water deficits that coincide with flowering result in leaf wilting, necrosis, tassel browning, and s
178 se of the chemoattractant and killing agents result in long-range chemotactic attraction, trapping, a
179 zalutamide plus androgen-deprivation therapy resulted in longer median overall survival than placebo
181 e preparation leads to detrimental cascades, resulting in loss of precious time, money and finally co
183 ry compared with an endoscopy-first approach resulted in lower pain scores when integrated over 18 mo
184 continuous exposure to rec-TF up to 14 days, resulted in lower PTEN antigen levels, enhanced Akt acti
185 trates required longer irradiation times and resulted in lower surface coverage at the same wavelengt
187 signaling, however, depletion of CD8 T cells resulted in lytic infection of the choroid plexus and ep
188 73/STING-dependent DNA sensor pathway, which results in macrophage infiltration and activation during
189 in cells and in vivo demonstrates promising results in many disease models, in which autophagy upreg
190 that low level exposure to diethyl phthalate results in measurable genomic changes in breast tissue w
191 nhibitors (ICIs) have achieved unprecedented results in melanoma, the biological features of the dura
192 ors governing the hypoxia signaling pathway, resulting in metabolic dysregulation, heightened angioge
194 or phosphorylated tau and total tau may thus result in misclassifications for non-amnestic Alzheimer'
195 trategies use either nonspecific conjugation resulting in mixtures, or site-specific methods that req
197 0 percentage points, an increase expected to result in more than 16 million individuals losing ESDI i
200 ibrin hydrogels pre-incubated with LN-511-E8 resulted in multilayered stratified epithelial construct
202 F improved dewatering of both foodstuffs and resulted in net dewatering efficiencies of 7.4% and 4.9%
204 ion and increased oxidative stress, possibly resulting in neurodegeneration in non-dividing cells.
205 rs modify the intrinsic kinetic mechanism to result in new molecular and cellular functionality.
207 ed by excellent DNA surveillance and repair, resulting in one of the lowest spontaneous mutation rate
209 activity and altered mtDNA copy number that result in organ dysfunction in aging and disease have of
210 intense cytoplasmic vacuolization, possibly resulting in osmotic stress; no accumulation of multiple
211 nd inter-observer variability in grading can result in overtreatment and undertreatment of prostate c
213 dens the class of possible interactions that result in peripheral positioning to include boundary int
216 adsorption of the three CMMs was performed, resulting in polyphenols adsorption increase due to thei
217 modules with non-native substrates primarily resulted in poor conversions to anticipated macrolactone
218 s of equipoise over the course of the trial, resulting in poor adherence to the assigned study treatm
219 ment transfer to heteronuclei, SABRE-SHEATH) resulted in positive enhancements of up to ~100-fold in
223 , inserted in the 3' UTR of the target gene, resulted in rapid self-cleavage and subsequent decay of
225 se of MELD-GRAIL-Na as compared with MELD-Na resulted in reclassification of 16.7% (n = 672) of patie
226 in lung cancer cell lines repolarized TAMs, resulting in recovered cytolytic activity and antitumora
228 sruption of the food matrix by prior cooking results in reduced carotenoid levels and transfer to the
232 ne tetrahydrofolate reductase (Mthfr), which results in retention of 1-carbon groups in the folate cy
233 a disease of the pulmonary vasculature that results in right heart failure and death, are usually as
235 for aromatic compound oxidation that do not result in ring hydroxylation, we identified products for
236 ein membrane-proximal external region (MPER) results in robust blocking of viral infection by a class
237 3 alterations are frame-shift mutations that result in several cancer-specific neoantigens that activ
239 Although it is well established that EBOV results in severe organ damage, our understanding of tis
241 Global deletion of Kir6.1 or SUR2 subunits results in severely impaired lymphatic contractile respo
243 velopment efforts.IMPORTANCE Ebola outbreaks result in significant morbidity and mortality in affecte
244 t levels of these biotic and abiotic factors resulted in significant variation in total plant mass, d
245 the trees are destroyed within a few months, resulting in significant environmental and economic loss
247 stance to stresses found that both mutations result in similar nuclear envelope perturbations that we
248 as as effective as a threshold of 90 g/L and resulted in similar HRQOL and HCT outcomes with fewer tr
250 Ectopic expression of ZIKV NS4B protein results in similar changes, demonstrating a role for NS4
251 4)(THF)(2)] with MOtBu (M = Na, Li) does not result in simple metathetic ligand exchange but entails
252 , Web of Science, as well as Google Scholar, resulted in six studies meeting the criteria of primary
254 and iodine content; particularly the latter results in small, yet, noticeable differences in VNC att
259 er density and suppresses bipolar diffusion, resulting in superior power factors than those of the Bi
260 es thus far have revealed a mixed pattern of results in support of either the "sharpening" or "dampen
261 , O -> S substitution in squaramide synthons resulted in supramolecular polymers with increased fiber
262 lls recapitulates the effects of fibroblasts resulting in sustained MTOR signaling and poor lapatinib
264 A lesion of primary visual cortex, V1, can result in the perceived size of objects varying with the
266 ing fact that growth of B. subtilis does not result in the significant accumulation of extracellular
267 o uncultured groups from the environment has resulted in the description of several new phyla, many o
268 esponses to bacterial molecular patterns and resulted in the expansion of lysozyme-sensitive mucolyti
269 ollowed by growth using a longer wavelength, resulted in the second-stage morphology exhibiting termi
270 ive than the previous one, and specifically, resulting in the formation of a known product, confirmed
271 n caused a durable loss of ventral identity, resulting in the generation of neurons with the characte
272 180 nm and 1 mum line spacing was achieved, resulting in the highest resolution EGaIn patterning tec
273 d be however purified by ultracentrifugation resulting in the mitigation of MCPDE levels by a factor
274 the most common neurodegenerative disorder, resulting in the progressive decline of cognitive functi
276 of serine protease inhibitor SerpinB9 (Sb9) results in the death of tumor cells in a granzyme B (GrB
277 e was successfully applied with satisfactory results in the determination of phthalate esters in yogu
278 P80 and failure therein of BRCA1 PARsylation results in the dysregulated accumulation in these foci o
281 c area of high glycan density on MERS S that results in the formation of oligomannose-type glycan clu
282 ar cycloaddition reaction (Prato's protocol) results in the formation of pyrrolidine rings bearing a
283 ical NF-kappaB signalling pathway by AZD5582 results in the induction of HIV and SIV RNA expression i
285 tion of a weakly basic triflate counteranion results in the stereoselective hydroalkynylation of the
286 or 3 (FGFR3) compounds are showing promising results in the treatment of bladder cancer, including in
288 docytosis in Abeta(25-35)-exposed astrocytes resulted in their retention at the cell surface in the f
289 ndent RNA polymerase 6-dependent small RNAs, resulting in their continued turnover likely to free the
290 n with the recombinant A4G (rA4G) RSV mutant resulted in transcriptional readthrough and lower G and
291 rabidopsis (Arabidopsis thaliana) AtSCS gene results in two in-frame transcripts and subsequently two
293 zygous loss-of-function mutations in SLC39A8 result in undetectable serum manganese (Mn) and a Congen
295 violations from theoretical models, this can result in unsubstantiated claims of a method's performan
296 lenge of animals given SARS or MERS vaccines resulted in vaccine hypersensitivity reactions (VAH), si