ライフサイエンスコーパス: retinal pigment epithelium

1 1% intraretinal, 38% subretinal, and 36% sub-retinal pigment epithelium).

2 e retina, separating photoreceptors from the retinal pigment epithelium.

3 ia but also throughout the retina and in the retinal pigment epithelium.

4 s well as degeneration of photoreceptors and retinal pigment epithelium.

5 their induced pluripotent stem cell-derived retinal pigment epithelium.

6 eduction of bisretinoid formation within the retinal pigment epithelium.

7 d by oxidative stress in the choroid and the retinal pigment epithelium.

8 rrected P < 10(-9)), even in areas of intact retinal pigment epithelium.

9 ved were drusen, atrophy, and changes to the retinal pigment epithelium.

10 of increased ICP, and perhaps changes in the retinal pigment epithelium.

11 e can suppress consumption of glucose by the retinal pigment epithelium.

12 sociated with perturbed melanogenesis in the retinal pigment epithelium.

13 istent with PVR, and reactive changes in the retinal pigment epithelium.

14 on, optic nerve head pallor, and mottling of retinal pigment epithelium.

15 tween the interdigitation zone and an intact retinal pigment epithelium.

16 ning of the cone outer segment closer to the retinal pigment epithelium.

17 in pigment cells, including melanocytes and retinal pigment epithelium.

18 represent progressive migration and loss of retinal pigment epithelium.

19 glia cells, and the basolateral side of the retinal pigment epithelium.

20 hed chromophores and recycling in the nearby retinal pigment epithelium.

21 ar surface ectoderm, lens, neuro-retina, and retinal pigment epithelium.

22 generalized dysfunction at the level of the retinal pigment epithelium.

23 ural crest, but only specifically around the retinal pigment epithelium.

24 acid transport between the neural retina and retinal pigment epithelium.

25 limbal eye stroma and epithelial cells from retinal pigment epithelium.

26 ge, indicative of pathological events in the retinal pigmented epithelium.

27 ated retina preparation after removal of the retinal pigmented epithelium.

28 9 screens against 27 genotoxic agents in the retinal pigment epithelium-1 (RPE1) cell line.

29 (1) hypertransmission, (2) disruption of the retinal pigment epithelium, (3) photoreceptor degenerati

30 undus photographs were graded for drusen and retinal pigment epithelium abnormalities and were evalua

31 o 17.6% (n = 37) in those 80 years or older, retinal pigment epithelium abnormalities from 4.1% (n =

32 Retinal pigment epithelium abnormalities, AVLs, neovascu

33 inal Muller cells, endothelial cells, and in retinal pigment epithelium; agonism of PPARalpha with ge

34 ound the injection site demonstrated diffuse retinal pigment epithelium alterations with dense hard e

35 location of vitamin A derivatives across the retinal pigment epithelium and Bruch's membrane, 2 tissu

36 The 2 biomarkers were RPE65 for retinal pigment epithelium and CD163 for histiocytes, ea

37 s proliferation of POM cells surrounding the retinal pigment epithelium and decreases the expression

38 ipofuscin accumulate in the lysosomes of the retinal pigment epithelium and display cytotoxic effects

39 Electron microscopy showed thinning of the retinal pigment epithelium and disruption of the externa

40 Quantifying preserved retinal pigment epithelium and EZ areas on FAF and OCT i

41 tors then export the lactate as fuel for the retinal pigment epithelium and for neighboring Muller gl

42 lly if multimodal imaging supports an intact retinal pigment epithelium and inner retina but an abnor

43 insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may lim

44 s in the choriocapillaris, Bruch's membrane, retinal pigment epithelium and occasionally neurosensory

45 ns in the choriocapillaris in the absence of retinal pigment epithelium and outer retinal abnormaliti

46 area using 2 distinct criteria: (1) complete retinal pigment epithelium and outer retinal atrophy (cR

47 ts and achieved a more rapid recovery of the retinal pigment epithelium and photoreceptor cells.

48 in the choriocapillaris, which supplies the retinal pigment epithelium and photoreceptors, and the c

49 lar components of individual granules in the retinal pigment epithelium and present their analytical

50 dal gammadelta T cells in protection against retinal pigment epithelium and retinal injury.

51 The normal retinal pigment epithelium and uveal melanocytes did not

52 s were associated with absence of underlying retinal pigment epithelium and were longer (r = -0.62; 9

53 H35.54 (dystrophies primarily involving the retinal pigment epithelium), and H35.50 (unspecified mac

54 xcavation involving the neurosensory retina, retinal pigment epithelium, and choroid in 4 eyes (44%).

55 Total retinal, retinal pigment epithelium, and choroid layer thickness

56 able degrees of atrophy of the outer retina, retinal pigment epithelium, and choroid, with outer reti

57 extent of structural alterations of the CC, retinal pigment epithelium, and photoreceptors with mult

58 quantitative characteristics of the choroid, retinal pigment epithelium, and retina were compared bet

59 ion, likely by promoting inflammation of the retinal pigment epithelium, and validate TLR2 as a novel

60 totoxicity and genotoxicity studies in human retinal pigment epithelium (ARPE-19) cells.

61 beneath the small irregular elevation of the retinal pigment epithelium at the site of the quiescent

62 eas of pathology revealed the following: (1) retinal pigment epithelium atrophy (with or without resi

63 Retinal pigment epithelium atrophy and photoreceptor lay

64 Retinal pigment epithelium atrophy and photoreceptor los

65 , because of the extent of photoreceptor and retinal pigment epithelium atrophy in the macula.

66 Retinal pigment epithelium atrophy was delineated on the

67 Retinal pigment epithelium-BM thickness, as measured by

68 ight thickening of the nerve fiber layer and retinal pigment epithelium-Bruch's membrane, with thinni

69 cted after semiautomatic segmentation of the retinal pigment epithelium/Bruch membrane complex.

70 In age-related macular degeneration, the retinal pigment epithelium can be damaged by light actin

71 Suppression of glucose consumption in the retinal pigment epithelium can increase the amount of gl

72 d by the analysis of LC/MS data from a human retinal pigment epithelium cell line (ARPE-19) grown on

73 y AMD, including Bruchs membrane thickening, retinal pigment epithelium cell loss, retinal functional

74 lesion perimeter (a measure of the number of retinal pigment epithelium cells exposed at the lesion b

75 ascularization and a decrease in mesenchymal retinal pigment epithelium cells in alphaB-crystallin kn

76 Retinal pigment epithelium cells were in the centre, pho

77 Finally, in primary human fetal retinal pigment epithelium cells, ligand binding to TLR2

78 ine, bipolar, horizontal, photoreceptor, and retinal pigment epithelium cells, thus exposing the anat

79 served in the mammalian cochlea and in human retinal pigment epithelium cells.

80 n epithelial-mesenchymal transition (EMT) of retinal pigment epithelium cells.

81 and photoreceptor-specific markers in human retinal pigment epitheliums cells.

82 sing cells revealed molecular resemblance to retinal-pigment epithelium cells, and anatomic analysis

83 the human visual system (retina, macula, and retinal pigment epithelium/choroid) reveals features of

84 maintains therapeutic levels of sunitinib in retinal pigmented epithelium/choroid and retina for more

85 angles, loss of pigment and thinning of the retinal pigment epithelium, choroidal thinning, undiffer

86 orders, resembling congenital hypertrophy of retinal pigment epithelium (CHRPE) lesions.

87 tics of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) involving the macula

88 disk ratio (3.8%), vessel tortuosity (2.5%), retinal pigment epithelium degeneration (2.5%), myelinat

89 Retinal pigment epithelium degeneration followed by reti

90 A; n = 9, collected from outside the zone of retinal pigment epithelium degeneration) were evaluated

91 changes correlating with different stages of retinal pigment epithelium degeneration.

92 nal pigment epithelium (RPE) layer in serous retinal pigment epithelium detachment (PED) with multi-c

93 ges of different retinal layers, such as the retinal pigment epithelium-drusen complex (RPEDC), were

94 l mice had thickening of Bruchs membrane and retinal pigment epithelium dysfunction.

95 howed a typical macular cherry-red spot with retinal pigment epithelium dystrophy in the middle perip

96 tion of the automatically provided boundary "retinal pigment epithelium fit" positioned at the level

97 e fellow eye, hemorrhage, and absence of sub-retinal pigment epithelium fluid at baseline were associ

98 lial detachment, intraretinal fluid, and sub-retinal pigment epithelium fluid were predictive of FS a

99 ntraretinal fluid, subretinal fluid, and sub-retinal pigment epithelium fluid.

100 sition was associated with protection of the retinal pigmented epithelium from damage caused by disea

101 terns of NIR-AF over the island of surviving retinal pigment epithelium: Group 1 (preserved NIR-AF ce

102 Retinal pigmented epithelium has plentiful melanosomes,

103 A uptake across the blood-retinal barrier or retinal pigment epithelium have not been identified.

104 , we use human induced pluripotent stem cell-retinal pigment epithelium (hiPSC-RPE) derived from pati

105 An in vitro model of human retinal pigment epithelium (HRPEsv) cells was treated wi

106 hemorrhages in 2 (17%) and 3 (18%); loss of retinal pigment epithelium in 1 (8%) and 4 (24%); and dr

107 terminated at a variable distance before the retinal pigment epithelium in 56.67% of eyes.

108 id zone and hyperreflectivity underlying the retinal pigment epithelium in 9 eyes (100%), retinal thi

109 monstrate that Mfsd2a is highly expressed in retinal pigment epithelium in embryonic eye, before the

110 ive foci were correlated with changes in the retinal pigment epithelium in eyes with age-related macu

111 TLR2 was robustly expressed by the retinal pigment epithelium in mouse and human eyes, both

112 ine the incidence of atrophic lesions of the retinal pigment epithelium in patients with Stargardt di

113 lindrical melanosomes forming the remains of retinal pigment epithelium indicates that it is a verteb

114 eceptor layer thickness: inner nuclear layer-retinal pigment epithelium (INL-RPE) and the specific su

115 ilized induced pluripotent stem cell-derived retinal pigment epithelium (iPSC-RPE) to test the potent

116 ite the several treatments available, if the retinal pigment epithelium is damaged, we have to cope w

117 nct morphologies arranged in layers, forming retinal pigment epithelium, is a synapomorphy of vertebr

118 (ELM-ISOS); and inner segment outer segment-retinal pigment epithelium (ISOS-RPE).

119 Progressive geographic atrophy (GA) of the retinal pigment epithelium leads to loss of central visi

120 A loss of the choriocapillaris/retinal pigment epithelium left a "window-defect", where

121 gh closely coupled, the results suggest that retinal pigment epithelium loss is more extensive than p

122 hypertransmission of light into the choroid, retinal pigment epithelium loss, and loss of outer retin

123 the retinal vasculature, optic atrophy, and retinal pigment epithelium loss.

124 tors of peripheral monocyte infiltration and retinal pigment epithelium migration, and their depletio

125 Mild disease presented with retinal pigment epithelium mottling, a patchy pattern of

126 gic functions of photoreceptor cells and the retinal pigmented epithelium necessitate precise gene re

127 arget of TLR2 signaling, was detected in the retinal pigment epithelium of human eyes, particularly i

128 point to subnormal lipofuscin levels in the retinal pigment epithelium or, alternatively, limitation

129 inal hyperreflective foci represent cells of retinal pigment epithelium origin that are similar to th

130 ted with acquired vitelliform lesions are of retinal pigment epithelium origin, and the natural cours

131 pment of ischemic infarction of the choroid, retinal pigment epithelium, outer part of the retina and

132 g vortex vein, congenital hypertrophy of the retinal pigment epithelium, pars plana, ora serrata pear

133 a, photoreceptor layer (PRL) outer segments, retinal pigment epithelium plus drusen (RPE+drusen) comp

134 physiological function of photoreceptors and retinal pigment epithelium requires precise regulation t

135 Interestingly, the retinal pigment epithelium, responsible for normal phago

136 usen phenotypes, including the occurrence of retinal pigment epithelium (RPE) abnormalities, choroida

137 The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenera

138 Frank atrophy of the retinal pigment epithelium (RPE) and a neovascular compl

139 opathy that begins around the age of 30 with retinal pigment epithelium (RPE) and Bruch's membrane ch

140 pear as hyperreflective deposits between the retinal pigment epithelium (RPE) and Bruch's membrane on

141 The human retinal pigment epithelium (RPE) and choroid are complex

142 nced by increased deposition of C5b-9 in the retinal pigment epithelium (RPE) and choroid.

143 se cause remains elusive, dysfunction of the retinal pigment epithelium (RPE) and dysregulation of co

144 ter segments is an important function of the retinal pigment epithelium (RPE) and it is essential for

145 Bestrophin1 (BEST1) is expressed in human retinal pigment epithelium (RPE) and mutations in the BE

146 depend on support functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutri

147 NH surfaces (BMOM, BMOH) and the terminal of retinal pigment epithelium (RPE) and ONH surfaces (RPEM,

148 oid zone disruption), components of complete retinal pigment epithelium (RPE) and outer retinal atrop

149 d pigmented Abca4(-/-) mouse model presented retinal pigment epithelium (RPE) and photoreceptor degen

150 roduced by neighboring epithelial cells, the retinal pigment epithelium (RPE) and podocytes, respecti

151 he interaction between autophagy impaired in retinal pigment epithelium (RPE) and the responses of ma

152 ration (AMD) is a progressive disease of the retinal pigment epithelium (RPE) and the retina leading

153 ration of cone photopigments may require the retinal pigment epithelium (RPE) and/or retinal Muller g

154 ations in the morphology and function of the retinal pigment epithelium (RPE) are common features sha

155 nner and outer boundaries of the choroid and retinal pigment epithelium (RPE) as well as the inner re

156 outer retinal disruption and atrophy of the retinal pigment epithelium (RPE) associated with ORT on

157 that photoreceptor atrophy can occur without retinal pigment epithelium (RPE) atrophy and that atroph

158 refied choriocapillaris in correspondence of retinal pigment epithelium (RPE) atrophy in 80% (n = 16)

159 est-corrected visual acuity (BCVA), age, and retinal pigment epithelium (RPE) atrophy were recorded a

160 ed on multimodal imaging and ocular history: retinal pigment epithelium (RPE) atrophy with treatment-

161 hannel is localized to the apical aspects of retinal pigment epithelium (RPE) cells and contributes t

162 polar cells, mitochondria, Muller cells, and retinal pigment epithelium (RPE) cells and were visualiz

163 Retinal pigment epithelium (RPE) cells are cultured on t

164 o evaluate the intraretinal migration of the retinal pigment epithelium (RPE) cells in age-related ma

165 Cholesterol accumulation beneath the retinal pigment epithelium (RPE) cells is supposed to co

166 h encodes cadherin-3, a protein expressed in retinal pigment epithelium (RPE) cells that may have a k

167 In human retinal pigment epithelium (RPE) cells, the primary site

168 require trophic and functional support from retinal pigment epithelium (RPE) cells.

169 in cell culture media was incorporated into retinal pigment epithelium (RPE) cells.

170 status, method of subretinal fluid drainage, retinal pigment epithelium (RPE) changes, and choroidal

171 eloping murine eye, melanin synthesis in the retinal pigment epithelium (RPE) coincides with neurogen

172 ound TRPV4 expression in the endothelium and retinal pigment epithelium (RPE) components of the BRB,

173 tory milieu in wild-type mouse, we triggered retinal pigment epithelium (RPE) damage/PRC death by sub

174 ed macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributabl

175 al dystrophy, characterised by extensive sub-retinal pigment epithelium (RPE) deposits, RPE atrophy,

176 discovery cohort of 4 eyes revealed that in retinal pigment epithelium (RPE) elevations with a great

177 nal fluid (IRF), subretinal fluid (SRF), sub-retinal pigment epithelium (RPE) fluid, and subretinal t

178 d induced pluripotent stem cells to generate retinal pigment epithelium (RPE) from an individual suff

179 eceptors in three-dimensional optic cups and retinal pigment epithelium (RPE) from iPSCs with this co

180 profiled mRNA levels in both neuroretina and retinal pigment epithelium (RPE) from mouse and baboon o

181 atrix (ECM) microenvironment surrounding the retinal pigment epithelium (RPE) has been implicated in

182 To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, a

183 ed using spectral-domain OCT with respect to retinal pigment epithelium (RPE) in 836 spectral-domain

184 lipid profiles specifically localized to the retinal pigment epithelium (RPE) in Abca4 (-/-) Stargard

185 s, the vascular/neural network in DR and the retinal pigment epithelium (RPE) in AMD.

186 o assess growth and maturation phases of the Retinal Pigment Epithelium (RPE) in-vitro at the cell la

187 Daily, the retinal pigment epithelium (RPE) ingests a bolus of lipi

188 While AMD histopathology involves retinal pigment epithelium (RPE) injury associated with

189 The retinal pigment epithelium (RPE) is a highly polarized e

190 The retinal pigment epithelium (RPE) is a key site of injury

191 The retinal pigment epithelium (RPE) is a monolayer of cobbl

192 The retinal pigment epithelium (RPE) is a monolayer of pigme

193 The retinal pigment epithelium (RPE) is a particularly vulne

194 interface between the neural retina and the retinal pigment epithelium (RPE) is critical for several

195 Lipofuscin in the retinal pigment epithelium (RPE) is the major source of

196 he long-term natural history of the residual retinal pigment epithelium (RPE) is unclear, with report

197 < 0.001-0.03) were: hyperreflective foci and retinal pigment epithelium (RPE) layer atrophy or absenc

198 is study was to evaluate focal damage in the retinal pigment epithelium (RPE) layer in serous retinal

199 s calculated from the SD-OCT and the area of retinal pigment epithelium (RPE) loss from the FAF.

200 e damage to mitochondrial DNA (mtDNA) in the retinal pigment epithelium (RPE) may play a key role in

201 ated kinase 1/2 (ERK1/2) is increased in the retinal pigment epithelium (RPE) of age-related macular

202 lel clinical phenotypes were observed in the retinal pigment epithelium (RPE) of individuals with but

203 shown that autophagy is dysfunctional in the retinal pigment epithelium (RPE) of the AMD donor eyes (

204 ther NLRP3 inflammasome activation mainly in retinal pigment epithelium (RPE) or rather in non-RPE ce

205 s in DPED, estimate of coverage by different retinal pigment epithelium (RPE) phenotypes in the DPED

206 nd that increased activation of Rap1a in the retinal pigment epithelium (RPE) reduces oxidative signa

207 ean (SD) height of 45.3 (36.1) mum above the retinal pigment epithelium (RPE) reference plane that wa

208 absolute measurements of vitreous (VIT) and retinal pigment epithelium (RPE) signal intensities, whi

209 ements were obtained from en face SS-OCT sub-retinal pigment epithelium (RPE) slab images.

210 dy the impact of miR-204 loss on retinal and retinal pigment epithelium (RPE) structure and function.

211 To investigate when retinal pigment epithelium (RPE) tears occur and their a

212 ek 100, including central macular mean EZ to retinal pigment epithelium (RPE) thickness (2q4: 26.6 mu

213 ted to OCT measurement parameters, including retinal pigment epithelium (RPE) thickness, central macu

214 roduce robust gene editing in vivo in murine retinal pigment epithelium (RPE) tissue and skeletal mus

215 d efficient genome editing in vivo in murine retinal pigment epithelium (RPE) tissue via subretinal i

216 rdly rectifying potassium ion channel in the retinal pigment epithelium (RPE) to maintain ionic homeo

217 abolite transport is a major function of the retinal pigment epithelium (RPE) to support the neural r

218 tiated, biologically and genetically defined retinal pigment epithelium (RPE) to the diseased human e

219 Retinectomies expose the retinal pigment epithelium (RPE) to the vitreous cavity;

220 ling demonstrated no adverse perturbation of retinal pigment epithelium (RPE) transcriptional program

221 Electron microscopy of the obelix(td15) retinal pigment epithelium (RPE) uncovered reduced phago

222 In contrast, the canonical retinal pigment epithelium (RPE) visual cycle produces e

223 rmalities in regions with normally appearing retinal pigment epithelium (RPE) were the loss of the PO

224 Proteins in the retinal pigment epithelium (RPE), a cell layer adjacent

225 lated macular degeneration (AMD) affects the retinal pigment epithelium (RPE), a cell monolayer essen

226 t), (3) retinal projection through SHRM onto retinal pigment epithelium (RPE), and (4) masking of cho

227 ted Cl(-) channel predominantly expressed in retinal pigment epithelium (RPE), and over 250 genetic m

228 en the inner and outer segments (IS/OS), the retinal pigment epithelium (RPE), and the choriocapillar

229 tina, resulting from loss of photoreceptors, retinal pigment epithelium (RPE), and underlying chorioc

230 e photoreceptor support system involving the retinal pigment epithelium (RPE), Bruch's membrane, and

231 this reisomerization occurs in the adjacent retinal pigment epithelium (RPE), but because ipRGCs are

232 a well-characterized pathway in cells of the retinal pigment epithelium (RPE), cone visual pigments a

233 on was found in the photoreceptor-supporting retinal pigment epithelium (RPE), especially in a zone c

234 h the coordinated terminal maturation of the retinal pigment epithelium (RPE), fenestrated choroid en

235 rusen, an accumulation of material below the retinal pigment epithelium (RPE), have long been establi

236 subretinal hyperreflective material (SHRM), retinal pigment epithelium (RPE), hyperreflective foci (

237 tinoid-containing lipofuscin pigments in the retinal pigment epithelium (RPE), increased oxidative st

238 n abundant membrane-associate protein in the retinal pigment epithelium (RPE), is a key retinoid isom

239 of TGF-beta signaling in the entire eye, the retinal pigment epithelium (RPE), or the vascular endoth

240 On B-scans, the choroid, retinal pigment epithelium (RPE), photoreceptor (PR) lay

241 n (lws) in red cone photoreceptors, while in retinal pigment epithelium (RPE), TH regulates expressio

242 ning of photoreceptor layers, despite intact retinal pigment epithelium (RPE), to approximately 70% o

243 The retinal pigment epithelium (RPE), which lies between the

244 artially met by Muller glia and cells of the retinal pigment epithelium (RPE), which provide essentia

245 ciations of ocular and systemic factors with retinal pigment epithelium (RPE)-Bruch's membrane (BM) c

246 The volumes of retinal pigment epithelium (RPE)-drusen complex, RPE-dru

247 ia 9.7, P = .001; SE -2.27 D [SD 4.65]), and retinal pigment epithelium (RPE)-related dystrophies (OR

248 A nonvisual opsin known as retinal pigment epithelium (RPE)-retinal G-protein-coupl

249 teractions of matured photoreceptors and the retinal pigment epithelium (RPE).

250 ds on proper interaction with the underlying retinal pigment epithelium (RPE).

251 ls in a model of chronic degeneration of the retinal pigment epithelium (RPE).

252 the retina, the ciliary margin (CM), and the retinal pigment epithelium (RPE).

253 d epithelial mesenchymal transition (EMT) of retinal pigment epithelium (RPE).

254 may regulate the phagocytosis of OSs by the retinal pigment epithelium (RPE).

255 teristics, especially the involvement of the retinal pigment epithelium (RPE).

256 epends on the retinoid cycle in the adjacent retinal pigment epithelium (RPE).

257 eracts with Ca(V) 1.3 Ca(2+) channels in the retinal pigment epithelium (RPE).

258 espread pigment clumping at the level of the retinal pigment epithelium (RPE).

259 mice lacking caveolin-1 specifically in the retinal pigment epithelium (RPE).

260 levels were higher in neural retina than in retinal pigment epithelium (RPE).

261 hotoreceptor outer segments (POS) within the retinal pigment epithelium (RPE).

262 e (ELM) and mild transient thickening of the retinal pigment epithelium (RPE)/Bruch's complex (Bc).

263 lammatory IL-1beta was markedly increased in retinal pigment epithelium (RPE)/choroid and positively

264 ntally regulated manner in chicken embryonic retinal pigment epithelium (RPE)/choroid in the absence

265 b readily penetrates the retina to reach the retinal pigment epithelium (RPE)/choroid with minimal su

266 fied negative regulator of the ER-associated retinal pigment epithelium (RPE)65 isomerase necessary f

267 the photoreceptor zone, ellipsoid zone, and retinal pigment epithelium (RPE, P < 0.001 and P = 0.005

268 cific with majority of the expression in the retinal pigmented epithelium (RPE) and limited expressio

269 herapy, but delivery of viral vectors to the retinal pigmented epithelium (RPE) and retina can be cha

270 Funduscopy revealed focal alterations in the retinal pigmented epithelium (RPE) and yellow retinal do

271 elated macular degeneration characterized by retinal pigmented epithelium (RPE) death; the RPE also e

272 The retinal pigmented epithelium (RPE) forms the outer blood

273 Accumulation of bis-retinoids in the retinal pigmented epithelium (RPE) is a hallmark of agin

274 One of the major biological functions of the retinal pigmented epithelium (RPE) is the clearance of s

275 ession, we delivered a wild-type Mfrp to the retinal pigmented epithelium (RPE) of Mfrp (rd6) /Mfrp (

276 ecific stem cells for neural retina (NR) and retinal pigmented epithelium (RPE) of the teleost medaka

277 ar, mutant eyes show substantially increased retinal pigmented epithelium (RPE) proliferation in the

278 enotype consisting of vision loss, increased retinal pigmented epithelium (RPE) stress, and increased

279 ipid metabolism involving dysfunction of the retinal pigmented epithelium (RPE) underlies the pathoge

280 alysis revealed predominant up-regulation of retinal pigmented epithelium (RPE)-specific genes associ

281 FH is expressed in the retinal pigmented epithelium (RPE).

282 iRNA)-processing enzyme DICER1 in the mature retinal pigmented epithelium (RPE).

283 pecialized phagocytes: Sertoli cells and the retinal pigmented epithelium (RPE).

284 chronic reactive oxygen species (ROS) in the retinal pigmented epithelium (RPE).

285 arance and accumulation of lipofuscin in the retinal-pigmented epithelium (RPE) and of lipoproteins a

286 le-layer sign (separation of hyperreflective retinal pigment epithelium [RPE] from Bruch's membrane,

287 n area >/=196350 mum2) and depigmentation of retinal pigment epithelium (slope of -19.17 for the NEI-

288 erived monocytes, together with RPE65 in the retinal pigment epithelium, supports differentiation tow

289 Retinal pigment epithelium tears act differently dependi

290 d on-study events (atrophy status, fibrosis, retinal pigment epithelium tears).

291 imes leading to a loss of photoreceptors and retinal pigment epithelium that manifests clinically as

292 Loss of retinal pigment epithelium, the presence of a thin choro

293 rystal mutant lacks pigmentation also in the retinal pigment epithelium, therefore enabling optical a

294 from the choroidal blood passes through the retinal pigment epithelium to the retina where photorece

295 r displacement of the temporal peripapillary retinal pigment epithelium (tRPE) from its position in c

296 Retinal pigment epithelium undulations and vascular dila

297 erve fiber layer, outer plexiform layer, and retinal pigmented epithelium using image guidance and se

298 bilateral soft drusen and depigmentation of retinal pigment epithelium was associated with substanti

299 and complete atrophy of the outer retina and retinal pigment epithelium were observed in both split-d

300 ss of external limiting membrane and loss of retinal pigment epithelium with hypertransmission of OCT