ライフサイエンスコーパス: retinoic acid

1 and is elicited by the vitamin A metabolite, retinoic acid.

2 ed with rapamycin or rapamycin and all-trans retinoic acid.

3 igation and is modulated by DC expression of retinoic acid.

4 mesenchymes, depending on a concentration of retinoic acid.

5 e generated in the presence of vitamin C and retinoic acid.

6 r own niche, which is high in Wnt and low in retinoic acid.

7 signaling pathways, including Wnt, Notch and retinoic acid.

8 1 (CHIR), BMP pathway antagonist Noggin, and retinoic acid.

9 al RARE in the ROL transporter stimulated by retinoic acid 6 (Stra6) gene are required for EtOH induc

10 cell-surface receptor known as stimulated by retinoic acid 6 (STRA6), which transports retinol into c

11 r retinoid-binding protein and stimulated by retinoic acid 6 protein showed significantly lower level

12 nergistically activating RXRalpha with 9-cis-retinoic acid (9-cis-RA), a natural ligand binding to th

13 nflammation mouse model in response to 9-cis retinoic acid (9cRA) and after lymphocyte-specific genet

14 he effect of the endogenous metabolite 9-cis retinoic acid (9cRA) on allergic sensitization is unknow

15 the neurorestorative effect of delayed 9 cis retinoic acid (9cRA) treatment for stroke.

16 he rate-limiting step in the biosynthesis of retinoic acid, a bioactive lipid molecule that regulates

17 tinol in ester form, preventing synthesis of retinoic acid, a cofactor for Treg generation.

18 Some serve on-site for the synthesis of retinoic acid, a hormone-like compound, which exerts ple

19 Spinal application of retinoic acid, a key molecule necessary for iMF, bypasse

20 ignalling, which can be rescued by exogenous retinoic acid, a molecule necessary for iMF.

21 following search terms: isotretinoin, 13-cis-retinoic acid, Accutane, retinoids, acitretin, surgery,

22 Retinoic acid, an active metabolite of dietary vitamin A

23 Upon treating APL with all-trans retinoic acid and achieving complete remission, the leve

24 Retinoic acid and its synthetic compound AM80 play roles

25 scriptional response of human MCF-7 cells to retinoic acid and TGF-beta, applied individually and in

26 corepressor (NCoR) and silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepr

27 tor corepressor (NCoR)/silencing mediator of retinoic acid and thyroid receptors (SMRT) corepressor c

28 ng and maturation include the Wnt, Hedgehog, retinoic acid, and Hippo signaling pathways.

29 PKC (protein kinase C) was induced by retinoic acid, and PKC inhibition also rescued the abnor

30 mediator of the renal protective effects of retinoic acid, and repair of the endogenous retinoic aci

31 Treatment with all-trans retinoic acid antagonizes stress-induced activation of d

32 l for oncogene-targeted therapies: all-trans retinoic acid (ATRA) and arsenic both target and degrade

33 al showed that the combination of all- trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is at le

34 until the recent identification of all-trans retinoic acid (ATRA) as a Pin1 inhibitor.

35 The identification of all-trans retinoic acid (ATRA) as a potent Pin1 inhibitor provides

36 arge clinical trials that included all-trans retinoic acid (ATRA) as part of induction, we assessed k

37 reversed for K1 and K10 by adding all-trans retinoic acid (ATRA) but increased for K2 in the absence

38 All patients received all-trans retinoic acid (ATRA) during induction, each consolidatio

39 The all-trans-retinoic acid (atRA) hydroxylase Cyp26a1 is essential fo

40 outcomes of patients treated with all-trans retinoic acid (ATRA) in combination with anthracycline-b

41 eacetylase inhibitor valproate and all-trans retinoic acid (ATRA) in treatment-naive elderly patients

42 All-trans retinoic acid (ATRA) increased IRF4 expression, restored

43 es the first evidence showing that all-trans retinoic acid (ATRA) induces the interaction and chromat

44 Additionally, we reveal that all trans retinoic acid (ATRA) induces VCP expression, creating a

45 In mammals, all-trans retinoic acid (ATRA) is instrumental to spermatogenesis.

46 valuated the impact of exposure to all-trans retinoic acid (ATRA) on wild-type NK and CD38KO NK cell

47 The combination of all-trans-retinoic acid (ATRA) plus arsenic trioxide (ATO) has bee

48 We recently reported that all-trans retinoic acid (atRA) rapidly (within minutes) activates

49 yeballs are a source of diffusible all-trans retinoic acid (ATRA) that allow their targeting by the E

50 We have also found that all-trans retinoic acid (ATRA) treatment increased AGAP2 protein l

51 All-trans retinoic acid (ATRA), a derivative of vitamin A, is a co

52 ts biologically active metabolite, all-trans retinoic acid (ATRA), exhibits a potent antiviral proper

53 All-trans-retinoic acid (atRA), the active metabolite of vitamin A

54 All-trans-retinoic acid (atRA), the active metabolite of vitamin A

55 n and leukemogenesis, and inhibits all-trans-retinoic acid (ATRA)-induced AML cell differentiation, t

56 udy, we present an effective model All-Trans Retinoic Acid (ATRA)-induced differentiation of HL-60 ce

57 TAL were associated with increased all-trans retinoic acid (ATRA)-induced differentiation, generation

58 arget gene expression and inhibits all-trans-retinoic acid (ATRA)-induced myeloid differentiation of

59 rectly and potently upregulated by all-trans retinoic acid (atRA).

60 N-SH) cells to neuronal cells with all-trans retinoic acid (ATRA).

61 y to another known limb teratogen, all-trans retinoic acid (atRA).

62 ing pancreatic stellate cells with all-trans-retinoic-acid (ATRA) reprograms pancreatic stroma to sup

63 Vitamin A (all trans retinoic acid, ATRA) treated leukemic cells had increase

64 in stem cells, which is mediated by cellular retinoic acid binding protein 1 (Crabp1).

65 nd in the retinoic acid-transporter cellular retinoic acid binding protein 1 (p < 0.05 vs. NC-HDL).

66 atment, we investigated the role of cellular retinoic acid binding protein 2 (CRABP2) in MPNST in vit

67 effect, depending on how it engages cellular retinoic acid binding proteins (CRABPs).

68 ember 5 (SDR16C5) and SDR16C6, contribute to retinoic acid biosynthesis in living cells and are also

69 ; however, their physiological relevance for retinoic acid biosynthesis in vivo remains unclear.

70 hich have substantially decreased endogenous retinoic acid biosynthesis, Fgf21 expression was increas

71 ted to its bioactive derivatives retinol and retinoic acid by the intestinal epithelium, yet little i

72 Finally, we find that retinoic acid controls the spatiotemporal dynamics of Hg

73 ytic capacity, enhance their ability to make retinoic acid, dampen their capacity to make inflammator

74 uding IL-13, cigarette smoke condensate, and retinoic acid deficiency, at concentrations and times th

75 -autonomously by increased expression of the retinoic acid-degrading enzyme CYP26B1.

76 Retinoic acid-dependent and -independent hallmark genes

77 ed from human pluripotent stem cells enables retinoic acid-dependent emergence of hepato-biliary-panc

78 IL-17, IL-22, and IFN-gamma in a STAT3- and retinoic acid-dependent manner.

79 nteract with RARalpha, and failed to inhibit retinoic acid-dependent transcriptional activity upon ex

80 The retinoic acid derivative fenretinide (FR) is capable of

81 nal toxicity and mitochondrial function on a retinoic acid-differentiated SH-SY5Y human neuroblastoma

82 e we measure the gene expression dynamics of retinoic acid driven mESC differentiation from pluripote

83 the natural killer (NK) cell receptor NKG2D, Retinoic Acid Early 1 (RAE1), is re-expressed in adult d

84 Notably, we also showed that treatment with retinoic acid enhanced NRIP1 binding to RARalpha RNA in

85 9-cis-retinoic acid enhances ST8SIA2 expression, providing a m

86 tk), driven by the promoter of stimulated by retinoic acid gene 8 (Stra8), a germ cell-specific gene

87 lates illumination differences and generates retinoic acid gradients that underlie the generation of

88 lyceride content in BAT, as well as impaired retinoic acid homeostasis, associated with decreased BAT

89 sis, associated with decreased BAT levels of retinoic acid in alcohol-consuming mice.

90 response to targeted therapy with all-trans retinoic acid in vivo was dependent on NB integrity.

91 These data suggest a retinoic acid-independent, non-tumor suppressor role of

92 e haploinsufficient for the SMS causal gene, Retinoic acid induced-1 (Rai1), were hypersensitive to l

93 th human transcription factor 20 (TCF20) and retinoic acid-induced 1 (RAI1)-that suppresses the adver

94 We have previously identified retinoic acid-induced gene G (Rig-G) as a tumor suppress

95 ells, and its expression decreased following retinoic acid-induced neuroblastoma differentiation.

96 acid receptor that doubles as a cytoplasmic retinoic acid-induced postsynaptic regulator of protein

97 re, we report that the sensing of IAV RNA by retinoic acid inducible gene I (RIG-I) initiates ZBP1-me

98 na fide RNA sensors, Toll-like receptors and retinoic-acid inducible gene-I (RIG-I)-like receptors in

99 The retinoic acid-inducible gene 1 (RIG-I) signaling pathway

100 f Toll-like receptor 7 (TLR7) and, possibly, retinoic acid-inducible gene I (RIG-I) after viral sensi

101 These defective RNAs bind to retinoic acid-inducible gene I (RIG-I) and initiate mito

102 (IFN-beta) by interacting with and degrading retinoic acid-inducible gene I (RIG-I) and melanoma diff

103 Retinoic acid-inducible gene I (RIG-I) receptor recogniz

104 Using retinoic acid-inducible gene I (RIG-I) signaling as a mo

105 as mitochondrial antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma dif

106 ognition receptors, such as the RNA helicase retinoic acid-inducible gene I (RIG-I), that sense viral

107 s to an increase in viral RNA recognition by retinoic acid-inducible gene I (RIG-I), thereby stimulat

108 late a robust interferon (IFN) response in a retinoic acid-inducible gene I (RIG-I)-dependent manner

109 oduction, most likely through suppression of retinoic acid-inducible gene I (RIG-I)-like receptor (RL

110 IFI16) as well as viral RNA receptors of the retinoic acid-inducible gene I (RIG-I)-like receptor (RL

111 Retinoic acid-inducible gene I (RIG-I)-like receptors (R

112 Mammalian retinoic acid-inducible gene I (RIG-I)-like receptors de

113 e cytoplasmic pathogen recognition receptor, retinoic acid-inducible gene I (RIG-I).

114 f the 2016-17 outbreak viruses, mediated via retinoic acid-inducible gene I (RIG-I).

115 fluenza virus genome replication can trigger retinoic acid-inducible gene I (RIG-I)/mitochondrial ant

116 zed after stimulation with TLR4, TLR7/8, and retinoic acid-inducible gene I agonists.

117 red type I interferon (IFN) signaling in the retinoic acid-inducible gene I-like receptor (RLR) pathw

118 nstream of Toll-like receptor 7 and possibly retinoic acid-inducible gene I.

119 ng oligomerization domain-like receptor, and retinoic acid-inducible gene RIG-like receptor pathways

120 ng oligomerization domain-like receptor, and retinoic acid-inducible gene RIG-like receptor signaling

121 te suppression of the TLR4 and the antiviral retinoic acid-inducible gene-I (RIG-I) pathways with cli

122 Upon sensing cytosolic viral RNA, retinoic acid-inducible gene-I-like receptors (RLRs) int

123 d pattern recognition receptors (PRRs), like retinoic acid-inducible I (Rig-I) and melanoma different

124 rization domain (NOD)-like receptors (NLRs), retinoic acid-inducible protein I (RIG-I)-like receptors

125 anoma differentiation-associated gene 5, and retinoic acid-inducible protein I in bronchial biopsy sp

126 he intestine, it increased the expression of retinoic acid-inducible target genes such as Aldh1a2, Dh

127 gnificantly attenuated by siRNA depletion of retinoic acid-inducible-I-like receptors (RLR) or adapto

128 s such as myxoma resistance gene 1 (Mx1) and retinoic acid-inducing gene-I (RIG-I).

129 ting the regulatory T cell-inducing molecule retinoic acid, inhibiting inflammatory cytokine producti

130 We demonstrate that retinoic acid is critical in establishing asymmetric pig

131 During vertebrate somitogenesis, retinoic acid is known to establish the position of the

132 The differentiation therapy, retinoic acid, is currently used in clinic, leading to t

133 tive oxygen and nitrogen species production, retinoic acid-mediated apoptosis, and RIG-I-like recepto

134 and (3) exhausted stem cells alter the local retinoic acid metabolism and maintain the epithelial tis

135 A sequencing, we show the role of endogenous retinoic acid metabolism in initiating transcriptional p

136 tor signaling in HBCs, together with altered retinoic acid metabolism within the niche, promote HBC l

137 alcohol has a significant impact on cellular retinoic acid metabolism, with resultant effects on its

138 genous gels demonstrated a stiffness-driven, retinoic-acid-modulated upregulation of SIRPalpha and th

139 In the absence of retinoic acid, MPNST cells depleted of CRABP2 had reduce

140 We then characterize a crucial role for retinoic acid nuclear receptors in controlling exit from

141 been applied, consistent with the effects of retinoic acid on alternative pathways for ceramide gener

142 However, retinoic acid only works in a subset of patients.

143 -SY5Y human neuroblastoma cells by all-trans retinoic acid, or oxidative stress induced by mitochondr

144 We reveal that retinoic acid organizes topography by specifying anterio

145 ILC2s expressed GATA-3, retinoic acid orphan receptor (RORC) 2, and RORalpha; we

146 entiation following treatment with all-trans retinoic acid (P = 3.1 x 10(-13) to 2.4 x 10(-30)).

147 retinoic acid, and repair of the endogenous retinoic acid pathway offers another potential therapeut

148 ion, low Myc levels and high expression of a retinoic acid program are characteristic for dHSCs.

149 Retinoic acid (RA) activates RA receptors (RAR), resulti

150 y the combination of two targeted therapies: retinoic acid (RA) and arsenic.

151 As expected retinoic acid (RA) and FGF are able to modulate HOX expr

152 Our data revealed for the first time that retinoic acid (RA) and histone deacetylase (HDAC) inhibi

153 intenance of somitogenesis symmetry requires retinoic acid (RA) and its coactivator Rere/Atrophin2.

154 B1) regulates the concentration of all-trans retinoic acid (RA) and plays a key role in germ cell dif

155 f ST2 expression in alveolar ECs to generate retinoic acid (RA) and supports the synthesis of RA from

156 scriptional network that integrates opposing retinoic acid (RA) and Wnt signals to determine the rate

157 th the differentiation-promoting activity of retinoic acid (RA) could provide an alternative strategy

158 direct interaction existed between APLNR and retinoic acid (RA) in the cancer regulatory network.

159 tudies have underscored the critical role of retinoic acid (RA) in the development of lineage-committ

160 Retinoic acid (RA) induces rapid differentiation of embr

161 Retinoic acid (RA) is an autocrine and paracrine signali

162 by nuclear receptors for estrogen (E(2)) or retinoic acid (RA) is associated with formation of chrom

163 CYP26B1, CRABP1 and RALDH3 establish dynamic retinoic acid (RA) landscapes in feather mesenchyme, whi

164 Inhibition of CYP450-mediated retinoic acid (RA) metabolism by RA metabolism blocking

165 of active vitamin D3 (VD3) and/or all-trans retinoic acid (RA) on wild-type mouse skin induces a hum

166 All-trans retinoic acid (RA) plays crucial roles in embryogenesis.

167 ular control of embryonic bilateral symmetry.Retinoic acid (RA) regulates the maintenance of somitoge

168 Retinoic acid (RA) regulates transcription via RA recept

169 Finally, we found that retinoic acid (RA) signaling affects the irx2a expressio

170 d homeostasis, as well as the involvement of retinoic acid (RA) signaling in the entire process.

171 Retinoic acid (RA) signaling is essential for multiple d

172 Previous studies have suggested that retinoic acid (RA) signaling is involved in diencephalic

173 Retinoic acid (RA) signaling is involved in various phys

174 cal and knock-down experiments show that the retinoic acid (RA) signaling promotes differentiation of

175 Retinoic acid (RA) signaling was identified as a regulat

176 e and shape, as well as SNPs associated with retinoic acid (RA) signaling-associated genes, have been

177 Aldehyde dehydrogenase 1A1 (ALDH1A1), a retinoic acid (RA) synthase, is selectively expressed by

178 l like receptor 3 (TLR3) to induce intrinsic retinoic acid (RA) synthesis in a pattern that predicts

179 Retinoic acid (RA) treatment blocked the P4 increase in

180 All-trans-retinoic acid (RA), a bioactive derivative of vitamin A,

181 Retinoic acid (RA), a metabolite of retinol (vitamin A),

182 Retinoic acid (RA), a vitamin A (retinol) derivative, ha

183 Here we show that retinoic acid (RA), signaling through its receptor (RAR)

184 er target tissues at converting vitamin A to retinoic acid (RA), which activates retinoic acid recept

185 A (retinol/ROL) can be oxidized to all-trans-retinoic acid (RA), which plays a critical role in stem

186 that the TME induces tumor cells to produce retinoic acid (RA), which polarizes intratumoral monocyt

187 s distal to their origin unless treated with retinoic acid (RA), which results in proximodistal (PD)

188 Here, we describe light-inducible polymeric retinoic acid (RA)-containing nanoparticles (NPs) with t

189 In all-trans retinoic acid (RA)-induced differentiation of acute prom

190 vealed that LSD1 silences transiently active retinoic acid (RA)-induced enhancers and their target ge

191 ccessibility and gene expression data from a retinoic acid (RA)-induced mouse embryonic stem cells (m

192 se 2 (RALDH2), a rate-limiting enzyme in the retinoic acid (RA)-producing pathway.

193 ifferentiate to enter meiosis in response to retinoic acid (RA).

194 e inputs, including the vitamin A metabolite retinoic acid (RA).

195 sion of integrin subunit alpha is induced by retinoic acid (RA).

196 which was regulated by enzymes that degrade retinoic acid (RA).

197 P450 26b1 (Cyp26b1)-mediated degradation of retinoic acid (RA).

198 wn to be coregulated by an extrinsic signal, retinoic acid (RA).

199 We identified several retinoic acid receptor (RAR) agonists that reduced secre

200 the dimerization and DNA binding behavior of retinoic acid receptor (RAR) and retinoid X receptor (RX

201 The retinoic acid receptor (RAR) and retinoid X receptor (RX

202 Here, we show that CBFA2T3 represses retinoic acid receptor (RAR) target gene expression and

203 sion of lamin-A is known to be controlled by retinoic acid receptor (RAR) transcription factors, but

204 Retinoic acid receptor (RAR)-beta signaling is involved

205 While human ILCPs express low levels of retinoic acid receptor (RAR)-related orphan receptor C (

206 ediated suppression of the expression of the retinoic acid receptor (RAR)-related orphan receptor gam

207 h repeat protein 2) and STRA6 (stimulated by retinoic acid receptor 6), apparently mediated by allele

208 arget and degrade its ProMyelocytic Leukemia/Retinoic Acid Receptor alpha (PML/RARA) driver.

209 ed critical developmental factors, including retinoic acid receptor alpha (RARA) and homeobox D (HOXD

210 10772119 and rs883868 disrupt the binding of retinoic acid receptor alpha (RARA) and Yin and Yang 1 (

211 ML) nuclear bodies (NBs) mediated by the PML-retinoic acid receptor alpha (RARalpha) oncoprotein.

212 transcriptome analysis in APA and identified retinoic acid receptor alpha (RARalpha) signaling as a c

213 a (PPARgamma), vitamin D receptor (VDR), and retinoic acid receptor alpha (RARalpha).

214 The retinoic acid receptor analog acitretin, which up-regula

215 cell expression of the transcription factor retinoic acid receptor beta (RARbeta) is essential for v

216 tochondrial dynamics in neurite outgrowth by retinoic acid receptor beta signaling.

217 authors present the crystal structure of the retinoic acid receptor beta-retinoic X receptor alpha (R

218 the quaternary architecture of multi-domain retinoic acid receptor beta-retinoic X receptor alpha (R

219 Expression levels of retinoic acid receptor gamma (NR1B3/RARG, encodes RARgam

220 Here we report that the cytoplasmic retinoic acid receptor gamma (RARgamma) controls recepto

221 , the authors show that the nuclear receptor retinoic acid receptor gamma is released from the nucleu

222 Retinoic acid receptor responder 2 (RARRES2) is transcri

223 ated by RA signaling that is mediated by the retinoic acid receptor responder protein 1 (RARRES1).

224 This process required RARalpha, a nuclear retinoic acid receptor that doubles as a cytoplasmic ret

225 the introduction of "photohormones" for the retinoic acid receptor, farnesoid X receptor, and estrog

226 We also demonstrate that the PML retinoic acid receptor-alpha (PML-RARalpha) oncofusion p

227 th rapamycin with or without agonists of the retinoic acid receptor-alpha (RARA), and their gene expr

228 Retinoic acid receptor-alpha is the key mediator of the

229 Here, we explored the role of retinoic acid receptor-beta (RARbeta) signaling in remye

230 rs of vitamin D receptor (VDR)/RXR-alpha and retinoic acid receptor-gamma (RAR-gamma)/RXR-beta are bo

231 Using reporter assays, ChIP assays, and retinoic acid receptor-gamma (RARgamma) knockout ESC lin

232 gh small-molecule thymus-specific isoform of retinoic acid receptor-related orphan nuclear receptor g

233 rentiation of Th17 cells is dependent on the retinoic acid receptor-related orphan nuclear receptor R

234 ugh inducing aryl hydrocarbon receptor (AhR)-retinoic acid receptor-related orphan nuclear receptor-g

235 Here we showed that retinoic acid receptor-related orphan receptor alpha (RO

236 sive analysis reveals an unexpected role for retinoic acid receptor-related orphan receptor gamma (RO

237 pin RNA (shRNA) to CD30(+) T cells to target retinoic acid receptor-related orphan receptor gamma t (

238 regulation by impairing microbiota-dependent retinoic acid receptor-related orphan receptor gamma t (

239 Retinoic acid receptor-related orphan receptor gamma-t (

240 ins under the control of keratin 5, CD4, and retinoic acid receptor-related orphan receptor gamma.

241 s response is driven by the master regulator retinoic acid receptor-related orphan receptor gammat (R

242 Retinoic acid receptor-related orphan receptor gammat (R

243 The retinoic acid receptor-related orphan receptor-gammat (R

244 The retinoic acid receptor-related orphan receptors RORalpha

245 In particular, the nuclear hormone receptor retinoic-acid-receptor-related orphan receptor gamma (RO

246 sms by which progesterone receptors (PR) and retinoic acid receptors (RAR) regulate CK5 expression an

247 In this study, we target specific retinoic acid receptors (RARs) to either PD duplicate (R

248 al cofactor that directly interacts with the retinoic acid receptors (RARs) to modulate retinoic acid

249 min A to retinoic acid (RA), which activates retinoic acid receptors (RARs).

250 inding to nuclear transcription factors, the retinoic acid receptors.

251 n which a changing gradient of the morphogen retinoic acid regulates the expression of guidance facto

252 Retinoic acid-related orphan receptor (ROR)-gammat, the

253 CD8(+) T cells that express retinoic acid-related orphan receptor (ROR)gammat (TC17

254 Mechanistically, they identified retinoic acid-related orphan receptor alpha (RORalpha) a

255 pression in livers of mice by activating the retinoic acid-related orphan receptor alpha, and induced

256 Retinoic acid-related orphan receptor beta (RORbeta) is

257 expression and histone modifications at the retinoic acid-related orphan receptor gammat (Rorgammat)

258 expression of the TH17 transcription factor retinoic acid-related orphan receptor gammat or intracel

259 egulatory T-cell subsets expressing CXCR3 or retinoic acid-related orphan receptor gammat, and demeth

260 r 4, B cell-activating transcription factor, retinoic acid-related orphan receptor gammat, and SMAD2

261 of Th17-associated genes IL-17A, IL-22, and retinoic acid-related orphan receptor gammat.

262 mat(lo) (promyelocytic leukemia zinc finger, retinoic acid-related orphan receptor gT) iNKT1 cell sub

263 , respectively, CYP27B1 and CYP24A1, and the retinoic acid-related orphan receptors (ROR) alpha (RORa

264 To understand retinoic acid resistance in glioma, we studied the turno

265 e development of new treatment protocols for retinoic acid-resistant patients.

266 The frequency of Retinoic Acid Response Element (RARE) sequences was incr

267 which results in dissociation of TACC1 from retinoic acid response elements and leads to transcripti

268 a complex in the nucleus that binds specific retinoic acid response elements in the absence of RA.

269 tor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but

270 in visual pigments, decreased expression of retinoic acid-responsive genes and photoreceptor cell lo

271 There was evidence of increased retinoic acid signaling in both human embryonic stem cel

272 sis that chronic alcohol consumption impairs retinoic acid signaling in brown adipose tissue (BAT), l

273 e stem cell genes is consistent with reduced retinoic acid signaling in the skin of the double-knocko

274 siRNA-mediated downregulation of retinoic acid signaling induces upregulation of LOXL1 an

275 key components of the STRA6 receptor-driven retinoic acid signaling pathway.

276 ddition, regionalized epicardial/mesothelial retinoic acid signaling regulates lymphangiogenesis, con

277 2, and PDX1 expression and increasing normal retinoic acid signaling that promotes diaphragm developm

278 osis point to a role for thyroid hormone and retinoic acid signaling, as well as phototransduction pa

279 rown/beige adipocyte formation via elevating retinoic acid signaling.

280 CRABP2 is a transcriptional co-activator of retinoic acid signaling.

281 ipose tissue may be mediated through altered retinoic acid signaling.

282 epresses Bco1 gene expression in response to retinoic acid signaling.

283 Loss of Hand2 also led to dysregulation of retinoic acid signalling and disruption of anterior-post

284 known roles for several pathways, among them retinoic acid signalling.

285 We generated and characterized mature retinoic acid-skewed dendritic cells (DC-RAs) and assess

286 Signaling pathways (retinoic acid, sonic hedgehog, and Notch) that pattern t

287 lant cultures of embryonic kidney rudiments, retinoic acid stimulated Nrip1 expression, whereas a pan

288 en we block fin bud development by impairing retinoic acid synthesis or Fgfr function, the entire str

289 failure to express a key enzyme involved in retinoic acid synthesis.

290 ventrolateral constitutive expression of the retinoic acid-synthesizing enzyme (RALDH1) in supporting

291 ion contributes to the therapeutic effect of retinoic acid, the main treatment for acne.

292 e retinoic acid receptors (RARs) to modulate retinoic acid transcriptional activity.

293 tations can cause CAKUT by interference with retinoic acid transcriptional signaling, shedding light

294 ng protein 4 and apolipoprotein M and in the retinoic acid-transporter cellular retinoic acid binding

295 ospho-Cx43, which was further accentuated by retinoic acid treatment and by the presence of risk alle

296 Within 2 h of retinoic acid treatment, Hoxa1 is rapidly recruited to t

297 Wnt5a and retinoic acid were found to exhibit differential effects

298 t5a and Raldh2, the synthesizing enzymes for retinoic acid, were further analyzed for their function

299 re kept inactive by the vitamin A derivative retinoic acid, which is synthesized and degraded locally

300 ubicin, cytarabine, etoposide, and all-trans-retinoic acid with or without GO.