ライフサイエンスコーパス: retinoid X receptor

1 RA signaling were partially mediated by the retinoid X receptor.

2 ) could be bound by vitamin D receptor (VDR)/retinoid X receptor.

3 and involves direct interaction with RAR and retinoid X receptor.

4 and was dependent upon dimerization with the retinoid X receptor.

5 ein modification and heterodimerization with retinoid X receptor.

6 tor, and their obligate heterodimer partner, retinoid X receptor.

7 LXRs or their heterodimerizing partner, the retinoid X receptor.

8 overexpression of its heterodimeric partner, retinoid X receptor.

9 e PLA2g2a promoter as a heterodimer with the retinoid X receptor.

10 elements and for heterodimerization with the retinoid X receptors.

11 embers of retinoic acid receptors (RARs) and retinoid X receptors.

12 (negative association), and liver X receptor/retinoid X receptor activation (positive association).

13 mined the neuronally directed effects of the retinoid X receptor agonist bexarotene in an aggressive

14 and a panel of retinoid acid receptor (RAR)/retinoid X receptor agonist treatments suggested that RA

15 We investigated the effects of bexarotene (a retinoid X receptor agonist), CD1530 (a retinoic acid re

16 Alternatively, retinoid X receptor agonists partially restored myelin d

17 Human retinoid X receptor alpha (hRXRalpha) plays a critical r

18 Retinoid X receptor alpha (RXR alpha) localized througho

19 kely to be directly NRF2-dependent including retinoid X receptor alpha (RXRA).

20 port that Nuclear receptor-related 1 (Nurr1):Retinoid X receptor alpha (RXRalpha) activation has a do

21 three closely related human NRs--HNF4alpha, retinoid X receptor alpha (RXRalpha) and COUPTF2--reveal

22 way that strongly inhibits the expression of retinoid X receptor alpha (RXRalpha) and suppresses the

23 Signaling pathways regulated by retinoid x receptor alpha (RXRalpha) are involved in hep

24 tor activated receptor-gamma (PPARgamma) and retinoid X receptor alpha (RXRalpha) complex was found t

25 ferator-activated receptor gamma (PPARgamma):retinoid X receptor alpha (RXRalpha) heterodimer.

26 Although the DeltaNCARs maintain full retinoid X receptor alpha (RXRalpha) heterodimerization

27 sactivation of BSEP and SHP promoters by FXR/retinoid X receptor alpha (RXRalpha) in HepG2 cells.

28 Retinoid X receptor alpha (RXRalpha) plays a pivotal rol

29 r partner to class II nuclear receptors, the retinoid X receptor alpha (RXRalpha) plays a vital physi

30 93T, it was possible to demonstrate that the retinoid X receptor alpha (RXRalpha) plus its ligand can

31 epatocyte nuclear factor 4alpha (HNF4alpha), retinoid X receptor alpha (RXRalpha) plus peroxisome pro

32 ediated by hepatocyte nuclear factor 4alpha, retinoid X receptor alpha (RXRalpha) plus peroxisome pro

33 tocyte nuclear factor 4alpha (HNF4alpha) and retinoid X receptor alpha (RXRalpha) plus peroxisome pro

34 ptors hepatocyte nuclear factor 4 (HNF4) and retinoid X receptor alpha (RXRalpha) plus peroxisome pro

35 s predicted to interact efficiently with VDR-retinoid X receptor alpha (RXRalpha) was identified in s

36 pharmacologically perturbed the activity of retinoid X receptor alpha (RXRalpha), a key hub within t

37 The retinoid X receptor alpha (RXRalpha), a key nuclear rece

38 We have examined the role of hepatocyte retinoid X receptor alpha (RXRalpha), an essential partn

39 ctive homodimers to active heterodimers with retinoid X receptor alpha (RXRalpha), and phosphorylatio

40 depends on vitamin A signals mediated by the retinoid X receptor alpha (RXRalpha), as the systemic mu

41 Retinoid X receptor alpha (RXRalpha), functioning as eit

42 interact in an agonist-dependent manner with retinoid X receptor alpha (RXRalpha), suggesting that th

43 Pbeta), forkhead box protein A2 (FOXA2), and retinoid X receptor alpha (RXRalpha), were markedly decr

44 ln275, Arg316 and Arg371 in nuclear receptor retinoid X receptor alpha (RXRalpha), where berberine co

45 xisome proliferator-activated receptor alpha-retinoid X receptor alpha (RXRalpha), with which PGC-1be

46 retinoic acid receptor alpha (RARalpha) and retinoid X receptor alpha (RXRalpha).

47 ncer cell apoptosis mediated via the nuclear retinoid X receptor alpha (RXRalpha).

48 oblastoma tumor suppressor protein (pRb) and retinoid X receptor alpha (RXRalpha).

49 onstitutive androstane receptor (CAR, NR1I3)/retinoid X receptor alpha (RXRalpha, NR2B1) heterodimer

50 mation weight matrix for vitamin D3 receptor/retinoid X receptor alpha (VDR/RXRalpha) binding sites w

51 Retinoid X receptor alpha [RXRalpha; nuclear receptor (N

52 hereby implicating activation of a PPARgamma-retinoid X receptor alpha complex.

53 charide/Interleukin 1 mediated inhibition of Retinoid X Receptor alpha function and decreased Retinoi

54 ited the DNA binding activity of a PPARgamma/retinoid X receptor alpha heterodimeric complex.

55 Cotreatment with a retinoid X receptor alpha ligand, 9-cis-retinoic acid, d

56 d to this site as a monomer, because neither retinoid X receptor alpha nor retinoid X receptor beta a

57 Ralpha, induced the recruitment of PPARalpha:retinoid x receptor alpha, but not PPARgamma coactivator

58 stored the DNA binding activity of PPARalpha/retinoid X receptor alpha, induced mRNA levels of PPARal

59 itation studies confirmed the recruitment of retinoid X receptor alpha, PPARalpha, and PGC1alpha on t

60 Surprisingly, occupancies of FXR, retinoid X receptor alpha, RNA polymerase II, and epigen

61 eptor, constitutive androstane receptor, and retinoid X receptor alpha.

62 d miR193 expression via transcription factor retinoid X receptor alpha.

63 istent with this suggestion, it appears that retinoid X receptor alpha/farnesoid X receptor alpha and

64 dogenous PPARgamma together with its partner retinoid-X receptor alpha (RXRalpha).

65 eptor gamma (PPAR-gamma) and its co-receptor retinoid-X-receptor alpha (RXR-alpha).

66 -2 motif of CAR3 and is markedly enhanced by retinoid X receptor-alpha (RXR) cotransfection.

67 r expression of vitamin D receptor (VDR) and retinoid X receptor-alpha (RXR) has not been investigate

68 In cohort 1, retinoid X receptor-alpha (RXRA) chr9:136355885+ and end

69 Association of the retinoid X receptor-alpha (RXRA) coreceptor to PML/RARA

70 Retinoid X receptor-alpha (RXRalpha) binds to DNA either

71 ing protein-alpha (Cebpalpha), Cebpbeta, and retinoid x receptor-alpha (Rxralpha) compared with untre

72 Retinoid X receptor-alpha (RXRalpha) is a potent regulat

73 how here that keratinocytic nuclear receptor retinoid X receptor-alpha (RXRalpha) regulates mouse ker

74 In addition, coexpression of retinoid X receptor-alpha (RXRalpha) resulted in nuclear

75 brate drugs were abrogated in the absence of retinoid X receptor-alpha (RXRalpha), a molecule known t

76 n availability as hepatic nuclear PPARgamma, retinoid X receptor-alpha (RXRalpha), and PPARgamma/RXRa

77 roach designed to identify novel ligands for retinoid X receptor-alpha (RXRalpha).

78 ing binding to other molecules including the retinoid X receptor-alpha (RXRalpha).

79 Nuclear receptors including retinoid X receptor-alpha and peroxisome proliferator-ac

80 d 14, and normal melanocyte distribution and retinoid X receptor-alpha expression.

81 specific target genes.The vitamin D receptor/retinoid X receptor-alpha heterodimer (VDRRXRalpha) regu

82 The vitamin D receptor/retinoid X receptor-alpha heterodimer (VDRRXRalpha) regu

83 ferator responsiveness via the PPARgamma and retinoid X receptor-alpha heterodimer.

84 Heterodimerization of PPARalpha to the retinoid X receptor-alpha resulted in even larger increa

85 pha, but were decreased in mice deficient in retinoid X receptor-alpha, the major heterodimerization

86 ith a selective PPARgamma antagonist or with retinoid X receptor and retinoic acid receptor ligands p

87 clear receptors that heterodimerize with the retinoid X receptor and then modulate at the transcripti

88 ediated by preferential interactions between retinoid X receptors and CYP4F promoter elements in epid

89 inoic acid receptors (retinoic acid receptor/retinoid X receptor) and glucocorticoid receptors are re

90 Sult2A1 chromatin to recruit VDR, RXR-alpha (retinoid X receptor) and PXR in mice injected with D(3)

91 lets, also in vitro translated PPARgamma and retinoid X receptor, and chromatin immunoprecipitation a

92 The glucocorticoid receptor, retinoid X receptor, and p53 underwent similar processin

93 by nuclear receptors retinoic acid receptor, retinoid X receptor, and thyroid hormone receptor and in

94 ic identity were linked to RUNX2, C/EBPbeta, retinoid X receptor, and vitamin D receptor binding site

95 th retinoic acid receptor, does not activate retinoid-X receptor, and is not a substrate for CYP26s,

96 unctional expression cloning approach, a gag-retinoid X receptor beta (gag-RXRbeta) fusion protein wa

97 We further identified and validated retinoid X receptor beta (RXRB) as the CRV receptor.

98 ecause neither retinoid X receptor alpha nor retinoid X receptor beta antibody supershifted the prote

99 nscription factors PPARalpha, PPARdelta, and retinoid X receptor beta; and (c) liver development asso

100 , all found in the MHC class III region; and retinoid X receptor, beta (RXRB),which resides in the MH

101 lly bind tretinoin and alitretinoin, whereas retinoid-X receptors bind only alitretinoin.

102 21 gene transcription was mediated by an FXR/retinoid X receptor binding site in the 5'-flanking regi

103 ites identified two vitamin D receptor (VDR)/retinoid X receptor binding sites in the 1-kb promoter r

104 s 1,25(OH)(2)D(3) induces rapid VDR and RXR (retinoid X receptor) binding to the Cyp24a1 gene in both

105 adipocyte differentiation favored PPARgamma, retinoid X receptor, C/EBPalpha, and C/EBPbeta binding s

106 peroxisome proliferator-activated receptor, retinoid X receptor, CCAAT/enhancer binding protein, and

107 element was associated with the VD receptor/retinoid X receptor complex in vitro.

108 Coexpression of TRbetaA1 with retinoid X receptor did not enhance regulation.

109 er and show that binding of the liganded VDR.retinoid X receptor directly impacts both the distal and

110 noid X Receptor alpha function and decreased Retinoid X Receptor expression was confirmed to occur 1-

111 f Fgf15 by vitamin A is mediated through the retinoid X receptor/farnesoid X receptor heterodimer and

112 imal promoter recruit retinoic acid receptor/retinoid X receptor from a distal RARE to form an enhanc

113 Disruption of retinoid X receptor function in young macrophages, using

114 Signaling via the retinoid X receptor gamma (RXR-gamma) has been shown to

115 ormone receptor siRNA library, we identified retinoid X receptor gamma (RXRgamma) instead as being in

116 receptors, retinoic acid receptor alpha and retinoid X receptor gamma, were up-regulated in response

117 D receptor (VDR), which heterodimerizes with retinoid X receptor, gamma (RXRG).

118 a direct transcriptional target for the LXR/retinoid X receptor heterodimer and that the ability of

119 (NRs), especially the liver X receptor (LXR)/retinoid X receptor heterodimer, as an important event i

120 ery in the peroxisome proliferator-activated/retinoid X receptor heterodimer.

121 IP205 in the context of a DNA-bound FXR/RXR (retinoid X receptor) heterodimer.

122 TRAP220 interacted predominantly with the TR.retinoid X receptor heterodimeric pair in a ligand-depen

123 Rather, LXR/retinoid X receptor heterodimers bound directly to a con

124 oic acid can activate retinoic acid receptor/retinoid X receptor heterodimers but not retinoid X rece

125 aling did not involve reduced binding of LXR/retinoid X receptor heterodimers to target gene promoter

126 hormone receptor (TR) homodimers, but not TR-retinoid X receptor heterodimers, to thyroid hormone res

127 to recruit constitutive androstane receptor-retinoid X receptor heterodimers.

128 s of the LXRbeta homodimer and LXRalpha:RXR (retinoid X receptor) heterodimers explains differences i

129 s are further magnified in the presence of a retinoid X receptor heteromeric partner.

130 tor/retinoid X receptor heterodimers but not retinoid X receptor homodimers in reporter cell assays.

131 association of the ligand-binding domain of retinoid X receptor in the presence and absence of 9-cis

132 )2D3-independent interaction between VDR and retinoid X receptors in primary keratinocytes, indicatin

133 that mediates promoter induction by LXR/RXR (retinoid X receptor) in transfection assays.

134 bition of IL-1beta-dependent genes by active retinoid X receptors involves antagonism of NF-kappaB si

135 of alpha-synuclein toxicity and suggest that retinoid X receptor ligands with appropriate pharmacolog

136 peroxisome proliferator-activated receptor, retinoid X receptor, liver X receptor, and activating pr

137 Similarly, ablation of retinoid X receptors loosens PML/RARA DNA binding, induc

138 udes the binding of the liver X receptor and retinoid X receptor (LXR/RXR) heterodimer to the DR-4 el

139 Arsenic-induced liver X receptor/retinoid X receptor (LXR/RXR) signaling inhibition is a

140 of matrix metalloproteases, liver X receptor/retinoid X receptor, nuclear factor erythroid 2-related

141 etic ligand for the nuclear hormone receptor retinoid X receptor, on the expression of matrix metallo

142 how that expression of genes involved in the retinoid X receptor pathway are decreased with ageing in

143 These results reveal the retinoid X receptor pathway as a positive regulator of m

144 Retinoid X receptor:peroxisome proliferative-activated r

145 Anti-miR-21 enhanced PPARalpha/retinoid X receptor (PPARalpha/RXR) activity and downstr

146 rogram in mammary epithelial cells through a retinoid X receptor/PPARgamma-mediated mechanism.

147 ), through binding to retinoic acid receptor-retinoid X receptor (RAR-RXR) heterodimers bound at RA r

148 er partner (SHP), and retinoic acid receptor/retinoid X receptor (RAR/RXR).

149 perfamily including retinoic acid receptors, retinoid X receptors (RAR and RXR, respectively), and pe

150 tg2 promoter and show that the element binds retinoid X receptor/RAR heterodimers in vitro, is occupi

151 on in response to 9-cis-RA as evident by the retinoid X receptor response element-luciferase assays.

152 In this review we focus on the role of retinoid X receptor, retinoic acid receptor, peroxisome

153 and migration, lower retinol, and abolished retinoid X receptor/retinoid A receptor transcriptional

154 ds bound to the ligand binding domain of the retinoid X receptor reveal key structural aspects that e

155 tinoid related orphan receptor Ror beta, and retinoid X receptor Rxr gamma.

156 ither BADGE nor BPA activated or antagonized retinoid "X" receptor (RXR) or PPARgamma in transient tr

157 were synthesized and assessed for selective retinoid X receptor (RXR) agonism.

158 thalenyl]-1-propenyl ) benzoic acid) and RAR/retinoid X receptor (RXR) agonist (9-cis-RA) promote exp

159 ious data demonstrate that bexarotene (Bex), retinoid X receptor (RXR) agonist, reduces soluble and i

160 Examination of three retinoid X receptor (RXR) agonists [Targretin (TRG), UAB

161 However, the expression of retinoid X receptor (RXR) alpha, peroxisomal proliferato

162 hether apocarotenoids activate or antagonize retinoid X receptor (RXR) alpha.

163 s unable to bind its nuclear binding partner retinoid X receptor (RXR) alpha.

164 served enrichment for liver X receptor (LXR)/retinoid X receptor (RXR) and farnesoid X receptor/RXR n

165 AEG-1 interacts with retinoid X receptor (RXR) and inhibits RXR function.

166 hormone receptor, which heterodimerizes with retinoid X receptor (RXR) and regulates transcription of

167 g protein (C/EBP), HNF3, and heterodimers of retinoid X receptor (RXR) and retinoic acid receptor (RA

168 The synthesis and bioactivity of the retinoid X receptor (RXR) antagonist 4-[(3'-n-butyl-5',6

169 ale gastropods, because of the activation of retinoid X receptor (RXR) at very low environmental conc

170 10R slightly but significantly decreased FXR/retinoid X receptor (RXR) binding affinity but enhanced

171 cognizable half site that is required for TR/retinoid X receptor (RXR) binding.

172 tor-activated receptor gamma (PPARgamma) and retinoid X receptor (RXR) by classical and nonclassical

173 The nuclear receptor retinoid X receptor (RXR) can regulate transcription thr

174 oth VDREs bound the vitamin D receptor (VDR)-retinoid X receptor (RXR) complex and drove reporter gen

175 rough interactions of NF-kappaB with the PXR.retinoid X receptor (RXR) complex.

176 eracts with retinoic acid receptor (RAR) and retinoid X receptor (RXR) constitutively, but hormone bi

177 hat competed with a normally functioning VDR-retinoid X receptor (RXR) dimer for binding to the vitam

178 Ligands that activate the nuclear receptor retinoid X receptor (RXR) display potent anticarcinogeni

179 Targeting retinoid X receptor (RXR) has been proposed as one of th

180 or, a transcriptional corepressor) from a TR*retinoid X receptor (RXR) heterodimer bound to a DR+4 th

181 multiprotein complex that assembles on a TR.retinoid X receptor (RXR) heterodimer in HeLa nuclear ex

182 ferator activated receptor-alpha (PPARalpha)/retinoid X receptor (RXR) heterodimer promotes transcrip

183 5(OH)(2)D(3)) via a vitamin D receptor (VDR)/retinoid X receptor (RXR) heterodimer that binds to two

184 a major transcriptional target for the NR4A-retinoid X receptor (RXR) heterodimer.

185 These response elements directly bind FXR/retinoid X receptor (RXR) heterodimers and confer the ac

186 cription by binding to RA receptor (RAR) and retinoid X receptor (RXR) heterodimers.

187 Retinoid X receptor (RXR) is a combinatorial partner for

188 The nuclear receptor retinoid X receptor (RXR) is a ligand-activated transcri

189 behavior of retinoic acid receptor (RAR) and retinoid X receptor (RXR) is revealed, and an extension

190 Retinoid X receptor (RXR) is the binding partner for PPA

191 anisms underlying the anti-cancer effects of retinoid X receptor (RXR) ligand (rexinoid) therapy are

192 The three-dimensional structure of the retinoid X receptor (RXR) ligand binding domain has been

193 The retinoic acid receptor (RAR) and retinoid X receptor (RXR) mediate the cellular effects o

194 ed receptor gamma (PPARgamma) interacts with retinoid X receptor (RXR) on PPAR response elements (PPR

195 tion was achieved through the binding of PXR-retinoid X receptor (RXR) or CAR-RXR heterodimers to dir

196 The retinoid X receptor (RXR) partners with numerous nuclear

197 Retinoid X receptor (RXR) plays a central role in the re

198 Retinoid X receptor (RXR) plays a pivotal role as a tran

199 orphan receptors and, in particular, of the retinoid X receptor (RXR) positioned nuclear receptors a

200 Retinoid X receptor (RXR) regulates key cellular respons

201 Retinoid X receptor (RXR) regulates several key function

202 In vitro studies demonstrated that the retinoid X receptor (RXR) retinoid, bexarotene, at biolo

203 itamin D receptor (VDR) FokI AA genotype and retinoid X receptor (RXR) rs7861779 TT genotype were ass

204 3254), are described and evaluated for their retinoid X receptor (RXR) selective agonism.

205 sed here expressed all RA receptor (RAR) and retinoid X receptor (RXR) subtypes (as detected by North

206 mechanisms that may cause aberrations in the retinoid X receptor (RXR) subunits, RXR-alpha and RXR-be

207 binding of retinoic acid receptor (RAR) and retinoid X receptor (RXR) to a dominant site in enhancer

208 he conventional retinoic acid receptor (RAR)/retinoid X receptor (RXR) to activate CREB.

209 heterodimeric transcription factors with the retinoid X receptor (RXR) to regulate diverse biological

210 (FXR), which binds as a heterodimer with the retinoid X receptor (RXR) to the FXR response element (F

211 g a co-activator of the LCPUFA-sensing PPARG-retinoid X receptor (RXR) transcription complex, may inf

212 A-I and is induced by liver X receptor (LXR)/retinoid X receptor (RXR) transcription factors.

213 a functional heterodimer between EcR and the retinoid X receptor (RXR) upon application of the chemic

214 (NRs) function as obligate heterodimers with retinoid X receptor (RXR), allowing integration of ligan

215 receptors (PPARs) form heterodimers with the retinoid X receptor (RXR), and PPAR-gamma has been inten

216 ion: thyroid hormone receptor beta (TRbeta), retinoid X receptor (RXR), and PPARalpha.

217 iption factors retinoic acid receptor (RAR), retinoid X receptor (RXR), and Sp-1 exhibited >2-fold in

218 a (PPARgamma) and its heterodimeric partner, retinoid X receptor (RXR), are effective agents for the

219 Nuclear receptors, such as the retinoid X receptor (RXR), are proteins that regulate a

220 did not require heterodimerization with the retinoid X receptor (RXR), indicating that FXR represses

221 by activating the retinoic acid receptor and retinoid X receptor (RXR), indirectly influencing RXR he

222 s additionally associated with regulation by retinoid X receptor (RXR), jun proto-oncogene (JUN), sin

223 ndrostane receptor, pregnane X receptor, and retinoid X receptor (RXR), modulate acetaminophen (APAP)

224 blished that as an obligate heterodimer with retinoid X receptor (RXR), PPARgamma binds directly repe

225 r hormone receptors that heterodimerize with retinoid X receptor (RXR), such as thyroid receptors, pe

226 Exposure to agonists of retinoid X receptor (RXR), the obligate heterodimer part

227 imers and heterodimers with PPARgamma or the retinoid X receptor (RXR), thereby competing with PPARga

228 Activation of the retinoid X receptor (RXR), which is involved in cell pro

229 selective ablation of the nuclear receptors retinoid X receptor (RXR)-alpha and RXR-beta in mouse ep

230 f hepatocyte nuclear factor (HNF)-1alpha and retinoid X receptor (RXR)-alpha to investigate whether a

231 s controlled by the transcription regulation retinoid X receptor (RXR)-liver X receptor (LXR) system.

232 tes fundamental biological processes through retinoid X receptor (RXR)-mediated gene expression, mole

233 However, when used in combination with a retinoid X receptor (RXR)-selective ligand, tazarotene c

234 We and others have shown that retinoid X receptor (RXR)-selective retinoids or "rexino

235 gh-affinity retinoid acid receptor (RAR)- or retinoid X receptor (RXR)-selective retinoids.

236 bexarotene, and their analysis in acting as retinoid X receptor (RXR)-specific agonists.

237 s an obligate heterodimer (CAR-RXR) with the retinoid X receptor (RXR).

238 dies to the vitamin D receptor (VDR) and the retinoid X receptor (RXR).

239 while 9-cis-retinoic acid also binds to the retinoid X receptor (RXR).

240 ion by binding DNA as a heterodimer with the Retinoid X receptor (RXR).

241 hormone metabolism as a heterodimer with the retinoid X receptor (RXR).

242 subfamily function as heterodimers with the retinoid X receptor (RXR).

243 ion, and apoptosis through activation of the retinoid X receptor (RXR).

244 ligand of Nurr1's heterodimerization partner retinoid X receptor (RXR).

245 Retinoid X receptor (RXR)/retinoic acid receptor (RAR) h

246 Retinoid X receptor (RXR)alpha is an essential partner o

247 PCR analyses showed increased PPAR mRNA and retinoid X receptor (RXR)alpha mRNA expression after exp

248 Because the effect of retinoid X receptor (RXR)alpha on arterial mononuclear l

249 The constitutive androstane (CAR) and retinoid X receptors (RXR) are ligand-mediated transcrip

250 The thyroid (TR) and retinoid X receptors (RXR) belong to the nuclear recepto

251 Bexarotene, a selective agonist for Retinoid X receptors (RXR) improves cognitive deficits a

252 soforms of retinoic acid receptors (RAR) and retinoid X receptors (RXR) with the exception of RXRgamm

253 RAR pan-agonists and Am580, but not retinoid X receptors (RXR)-agonists, stimulate the expre

254 D receptor (VDR), which heterodimerizes with retinoid X receptors (RXR).

255 id receptors (RAR-alpha, -beta, -gamma), and retinoid X receptors (RXR-alpha, -beta, -gamma) was perf

256 ion of retinoic acid receptor (RAR-beta) and retinoid X receptors (RXR-beta, -gamma) was significantl

257 Most studies on the nuclear retinoid-X receptor (RXR) have focused on its role as a

258 tor-activated receptor gamma (PPARgamma) and retinoid-X receptor (RXR) ligands on AIB3(+/-)/PyMT cell

259 ysone Receptor (EcR) and Ultraspiracle (USP)/Retinoid-X Receptor (RXR).

260 h activation of its heterodimer partner, the retinoid-X-receptor (RXR), was also readily detected by

261 Retinoid X receptor (RXRalpha) is activated by 9-cis-ret

262 totic effect was associated with loss of the retinoid X receptor (RXRalpha) protein in the adenocarci

263 ns of retinoic acid receptor (RARLBD) and of retinoid X receptor (RXRLBD).

264 Bexarotene-activated retinoid X receptors (RXRs) ameliorate memory deficits i

265 ic acid receptors (RARs) heterodimerize with retinoid X receptors (RXRs) and bind to RA response elem

266 fatty acid sensing nuclear receptor families retinoid X receptors (RXRs) and peroxisome proliferator-

267 Retinoid X receptors (RXRs) are important transcriptiona

268 Here, we demonstrate that retinoid X receptors (RXRs) are key elements of the tran

269 iferator-activated receptors (PPARs) and the retinoid X receptors (RXRs) are ligand-activated transcr

270 The retinoid X receptors (RXRs) are members of the family of

271 Retinoid X receptors (RXRs) are nuclear receptors that c

272 Retinoid X receptors (RXRs) are obligate partners for se

273 Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are transcription factors th

274 Retinoid X receptors (RXRs) comprise a family of nuclear

275 sms underlying neuritogenesis, we found that retinoid X receptors (RXRs) control neuritogenesis.

276 Retinoids that activate the nuclear retinoid X receptors (RXRs) display potential for chemop

277 Retinoid X receptors (RXRs) function as ligand-activated

278 activates retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in vitro.

279 t activation of liver X receptors (LXRs) and retinoid X receptors (RXRs) inhibits apoptotic responses

280 rodimeric binding partners of PPARgamma, the retinoid X receptors (RXRs), showed additive enhancement

281 Agonists of retinoid X receptors (RXRs), which include the natural 9

282 s of retinoic acid (RA) signaling, including retinoid X receptors (RXRs).

283 a and liver X receptors in coordination with retinoid X receptors (RXRs).

284 (RA) are mediated by RA receptors (RARs) and retinoid X receptors (RXRs).

285 reas rexinoids are selective ligands for the retinoid X receptors (RXRs).

286 vious studies of the retinoid, bexarotene, a retinoid X receptor-specific ligand, have indicated that

287 e expression of known retinoic acid receptor/retinoid X receptor target genes, whereas GW0742 did not

288 lly targeted by bexarotene, a ligand for the retinoid X receptor that forms heterodimers with Nurr1.

289 thelium, and we identify an inhibitor of the retinoid X receptor that improves intestinal regeneratio

290 factors are the retinoic acid receptor, the retinoid X receptor, the hepatocyte nuclear factor 4alph

291 ATRA signaled through the retinoid X receptor to decrease BCR-ABL leukemic cell vi

292 monstrated specific binding of PPARgamma and retinoid X receptor to the human and mouse pdx-1 x PPREs

293 omoted binding of the vitamin D receptor and retinoid X receptor to the promoters of osteoblastic tar

294 tation assay demonstrated binding of RAR and retinoid X receptor to the RA response element.

295 )2D3 increased recruitment of Vdr and rodent retinoid X receptor to the Shp promoter.

296 Binding of the vitamin D/retinoid-X receptor (VDR/RXRalpha) heterodimer to the AC

297 ts with a DNA response element known to bind retinoid X receptor-VDR heterodimers.

298 inoid receptors (retinoic acid receptors and retinoid X receptors), which are nuclear transcription f

299 DHA stimulates the retinoid X receptor, which reportedly regulates the expr

300 specific nuclear retinoic-acid receptors and retinoid-X receptors, which are encoded by separate gene