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3 In birds and nonprimate mammals, both the retinotectal and retinogeniculate pathways contribute cr
5 the expression of ephrin-As on axons of the retinotectal and vomeronasal projections suggests that t
10 ic HS sequences are essential for regulating retinotectal axon targeting and suggest that regionalise
12 lation in vitro and to rescue alterations of retinotectal axonal pathfinding induced by loss of NOVA2
14 tinotectal axons was investigated by imaging retinotectal axons labeled with the fluorescent indicato
16 n 5-HT it induces, on the terminal arbors of retinotectal axons rather than on their parent cells.
17 of melatonin on calcium dynamics in Xenopus retinotectal axons was investigated by imaging retinotec
18 since depolarization-evoked calcium rises in retinotectal axons were inhibited by GABA(C) receptor bl
19 ta therefore support the hypothesis that, in retinotectal axons, melatonin reduces cAMP levels, there
20 ls, GABA(C) receptors mediate inhibition, in retinotectal axons, the opposite appears to occur since
29 induce persistent modification of developing retinotectal circuits via spike timing-dependent plastic
30 development of the temporonasal axis of the retinotectal/collicular map, but the role of these molec
34 rbor size during formation and maturation of retinotectal connectivity and degraded functional proces
35 which is required for Eph receptor-dependent retinotectal development in chick and for development of
37 e test the role of axon-axon interactions in retinotectal development, by devising a technique to sel
40 cing intracellular calcium concentrations in retinotectal fibers in the frog optic tectum in vitro.
41 ectum, using confocal imaging of DiI-labeled retinotectal fibers in whole-mount tecta of embryos pret
44 Despite several studies, knowledge of the retinotectal guidance molecules is far from being comple
46 al layers, as demonstrated by destruction of retinotectal input by intraocular application of the dru
48 spensable for coarse topographic ordering of retinotectal inputs but does contribute to the fine-scal
57 uit, during a period in development when the retinotectal map undergoes activity-dependent refinement
58 priate to contribute to the formation of the retinotectal map, and we suggest that these methods be u
59 e influence the fine-scale topography of the retinotectal map, indicating that lineage relationships
66 s an axon guidance molecule, plays a role in retinotectal mapping along the medial-lateral axis, coun
69 requirement for endogenous EphA receptors in retinotectal mapping, show that the receptor intracellul
74 f their expression gradients with developing retinotectal maps and gradients of cellular development
77 est that nucleus isthmi input can facilitate retinotectal neurotransmission, and the mechanism could
81 These fibers may represent either a novel retinotectal pathway or collateral branches from centrif
82 lves a shift in visual processing toward the retinotectal pathway, and that gene therapy partially re
83 e that NO has some signaling function in the retinotectal pathway, but this function is not critical
87 rities and shared anatomical position in the retinotectal processing stream, carry out diverse, task-
89 -thymidine neuronography, we have mapped the retinotectal projection and the spatiotemporal progressi
90 olved in refinement of the topography of the retinotectal projection as well as in other aspects of r
91 visual system, topographic refinement of the retinotectal projection depends on electrical activity.
94 resent a detailed phenotypic analysis of the retinotectal projection in nev and show that dorsonasal
97 ptor-mediated elimination of the ipsilateral retinotectal projection is completely mediated via nitri
99 ing of retinal axons after the time that the retinotectal projection is normally topographically orga
102 conclusion that the effect of 5,7-DHT on the retinotectal projection may primarily be a function of t
103 dertaken to determine whether changes in the retinotectal projection of 5,7-DHT-treated animals were
108 , resulted in abnormalities in the uncrossed retinotectal projection similar to those observed in the
109 o the embryonic chick eye in vivo caused the retinotectal projection to develop without normal topogr
110 st that Tctp supports the development of the retinotectal projection via its regulation of pro-surviv
114 d in oligodendrocytes along the regenerating retinotectal projection, mirroring up-regulation of endo
115 ions during the formation of the topographic retinotectal projection, we coexpressed cytosolic fluore
129 inal OFF pathway controls turn movements via retinotectal projections and establishes correct orienta
131 elimination of topographically inappropriate retinotectal projections in a dose-dependent manner.
133 es between the organization of the uncrossed retinotectal projections of 5-HT-treated animals vs. eit
134 tp deficiency results in stunted and splayed retinotectal projections that fail to innervate the opti
135 placed over the SC on either P-1 or P-3, and retinotectal projections were assessed via anterograde t
136 ormalities in both the crossed and uncrossed retinotectal projections when these animals reach adulth
146 ELF-1 could determine nasal versus temporal retinotectal specificity, and providing a direct demonst
147 rons indicate that CPG15 expression promotes retinotectal synapse maturation by recruiting functional
148 f ephrin-B signaling increased the number of retinotectal synapses and stabilized the axon arbors of
150 elatively immature synaptic circuit in which retinotectal synapses are formed on developing filopodia
154 ely occluded long-term potentiation (LTP) of retinotectal synapses induced by direct electrical stimu
155 in the number of docked synaptic vesicles at retinotectal synapses made by RGC axons expressing GFP-T
156 e report that LTP and LTD induced in vivo at retinotectal synapses of Xenopus tadpoles undergo rapid
158 Xenopus tectal neurons shows that convergent retinotectal synapses undergo activity-dependent coopera
160 um, which induced persistent potentiation of retinotectal synapses, led to a rapid modification of sy
161 short period after the initial formation of retinotectal synapses, spike visual RFs of tectal neuron
168 ownstream of NMDA receptor activation during retinotectal synaptic competition because NMDA receptor
169 It is possible, however, that BDNF modulates retinotectal synaptic connectivity by differentially inf
174 performed in vivo imaging of the developing retinotectal system in the larval zebrafish to character
176 of the optic nerve in the developing Xenopus retinotectal system induces long-term potentiation (LTP)
178 recise axon pathfinding and targeting in the retinotectal system of the zebrafish (Danio rerio).
179 xpression of Homer in the developing Xenopus retinotectal system results in axonal pathfinding errors
180 ultrastructural organization of the Xenopus retinotectal system to understand better the maturation
181 , ligands for EphB2, in the developing chick retinotectal system using riboprobes, immunocytochemistr
182 alization of guidance cues in the developing retinotectal system, a three-compartment chamber was cre
186 In addition, as has been demonstrated in the retinotectal system, some of these genes are likely to c
187 report here that, in the developing Xenopus retinotectal system, the receptive field of tectal neuro
188 nce of topographically organized maps in the retinotectal system, we performed longitudinal visual re
192 f optimal shape, as might be relevant in the retinotectal system.Two distinct spatial limits on guida
193 5 protein is exported along RGC axons to the retinotectal terminals and may act as a neurotrophin car
195 ial interactions suggest that development of retinotectal topography critically depends on cell-speci
198 lopmental increase in AMPA receptor-mediated retinotectal transmission and increased GABAergic synapt
202 by information transmitted via the midbrain (retinotectal) visual pathway, and attention was probably