ライフサイエンスコーパス: retrograde

1 Retrograde (53% versus 30%, P<0.001) and antegrade disse

2 wth cone velocity by regulating the internal retrograde actin flow in an N-cadherin-dependent fashion

3 e variants of the same principle of coupling retrograde actin flow to the environment and thus can po

4 ortical actin belts in spheroids, and slowed retrograde actin flow.

5 transported, ultimately suggesting Jip3 is a retrograde adapter of active Ret51.

6 de amnesia), together with temporally graded retrograde amnesia covering ~5 y prior to the cardiac ar

7 These studies may help explain retrograde amnesia following seizures.

8 oadly, triggering windows of anterograde and retrograde amnesia in healthy people.

9 which was prevented under anisomycin-induced retrograde amnesia.

10 Hence, we administered a combination of retrograde and anterograde tracers into structures impor

11 Combined retrograde and anterograde tracing identified the parave

12 ctions to the VTA through cell-type-specific retrograde and anterograde tracing.

13 gral membrane proteins from the endosome via retrograde and plasma membrane recycling pathways.

14 ange of secondary metabolites, combined with retrograde and reactive oxygen signalling, provides exqu

15 been performed in over 150 patients using a retrograde approach that can be technically challenging.

16 onclusive evidence for existence of acquired retrograde axonal degeneration that is truly trans-synap

17 protein, pUL37, is an essential effector of retrograde axonal transport and also houses a deamidase

18 of this strain can induce optic neuritis by retrograde axonal transport from the brain to the retina

19 id variants with refined properties, such as retrograde axonal transport in specific subtypes of neur

20 HSV-1 pUL37 contributes to the neuroinvasive retrograde axonal transport mechanism.

21 cells, performing functions that range from retrograde axonal transport to mitotic spindle assembly(

22 neurons via their distal axons and spread by retrograde axonal transport to the neuronal cell bodies.

23 the spike has a role in MHV pathogenesis and retrograde axonal transport.

24 T tau, likely due to differential effects on retrograde axonal transport.

25 ty in pcd neurons and noted markedly reduced retrograde axonal transport.

26 APK8IP3 has been shown to be involved in the retrograde axonal-transport machinery, but many of its s

27 relates with valvular dysfunction and severe retrograde blood flow that persist into adulthood.

28 Retrograde BMP signaling and canonical pMad/Medea-mediat

29 ith dopamine beta-hydroxylase, as well as by retrograde bone-brain tracing using a sympathetic nerve-

30 bove systemic arterial values, suggestive of retrograde capillary blood aspiration, were discarded, l

31 starch mobilization to dawn does not require retrograde carbon signaling to the transcriptional clock

32 The Erv41-Erv46 complex is a conserved retrograde cargo receptor that retrieves ER resident pro

33 vesicle coat complex that mediates primarily retrograde cargo traffic in the Golgi.

34 s mechanism is essential for the delivery of retrograde cargos to the TGN.

35 nstrate that ARFRP1 is a master regulator of retrograde-carrier tethering to the TGN.

36 calyces, maximum 60 mg per instillation) via retrograde catheter to the renal pelvis and calyces.

37 be understood, the frequency and function of retrograde (cell body directed) mitochondrial transport

38 ates the connection between RNA turnover and retrograde chloroplast-to-nucleus signaling independentl

39 Endoscopic retrograde cholangio-pancreatography (ERCP) is commonly

40 er surgery and 21.9% (7/32) after endoscopic retrograde cholangiography (ERC).

41 l of 37 patients who had MRCP and endoscopic retrograde cholangiography (ERCP) were included.

42 iliary cannulation (SBC) and post endoscopic retrograde cholangiography and pancreatography (ERCP) co

43 nd severity of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP) in high-risk

44 -level data on the performance of endoscopic retrograde cholangiopancreatography (ERCP) in the United

45 enteral feeding, judicious use of endoscopic retrograde cholangiopancreatography (ERCP), and gallblad

46 the most feared complications of endoscopic retrograde cholangiopancreatography (ERCP), with an inci

47 Endoscopic retrograde cholangiopancreatography and balloon trawling

48 e bile of PSC patients undergoing endoscopic retrograde cholangiopancreatography earlier in their cli

49 rasound examinations, and 169,500 endoscopic retrograde cholangiopancreatography procedures were perf

50 lowing abdominal trauma, surgery, endoscopic retrograde cholangiopancreatography, and gallstones.

51 analysis from tissue extracted by endoscopic retrograde cholangiopancreatography.

52 ut could not be detected in cilia, even when retrograde ciliary transport was blocked.

53 The patient was cooled to 34.0 degrees C and retrograde cold blood cardioplegia was infused continuou

54 -augmin subunits increased the percentage of retrograde comets initiated at boutons, indicating that

55 rotein translation in the axon to facilitate retrograde communication to the soma and amplify neurona

56 ination of the pulmonary circulation and the retrograde contribution of the left heart.

57 ort of proteins from distinct domains in the retrograde direction likely due to coendocytosis along t

58 umber of them are displaced in the opposite (retrograde) direction.

59 nal motion state in both the anterograde and retrograde directions and a stationary state.

60 p in the asthenosphere explains the peculiar retrograde displacement revealed by seafloor geodesy, wh

61 rade wire escalation (N=24), ADR (N=35), and retrograde dissection and reentry (N=44).

62 antegrade dissection and reentry (ADR), and retrograde dissection and reentry.

63 ecretion of basement membrane components via retrograde dynein-dependent endosomal trafficking that r

64 further investigation for the possibility of retrograde ejaculation with urine cytology, the results

65 sor of neuronal activity and an amplifier of retrograde electrical signaling in the cerebral vasculat

66 n be fully explained by the disengagement of retrograde endocannabinoid signaling selectively at exci

67 nsion, possibly by TANGO1-mediated fusion of retrograde ERGIC membranes and (ii) by force application

68 ation and AF triggers that can be ablated by retrograde ethanol infusion.

69 polymerization at dendrite tips; they drive retrograde extension of an actin filament array that spe

70 We show that these dendrites develop by retrograde extension, in which the nascent dendrite endi

71 l molecular mechanism for dendrite growth by retrograde extension.

72 rs in an anterograde (from entry to exit) or retrograde fashion are still strongly debated.

73 ors are committed progenitors that lack such retrograde fate plasticity.

74 ow, because inhibition of endocytosis blocks retrograde flow and motility.

75 that swimming is five times slower than the retrograde flow of cortex and also that lymphocytes are

76 Here the retrograde flow of the actin cytoskeleton follows the te

77 RN-tre depletion led to an increase in actin retrograde flow rate and cellular contractility in S2 an

78 Net flow, peak velocity, retrograde flow, and retrograde fraction were measured o

79 nsion in WAVE1 KO cells are offset by faster retrograde flow, and therefore do not translate into fas

80 In growth cones, Pfn1 increased actin retrograde flow, MT growth speed, and invasion of filopo

81 lsatility was positively associated with the retrograde flow.

82 afferent connectivity of the mouse RE using retrograde Fluoro-Gold tracing.

83 et flow, peak velocity, retrograde flow, and retrograde fraction were measured on 14 analysis planes.

84 oligomeric Golgi (COG) complex and multiple retrograde Golgi Q-SNAREs (where SNARE is soluble NSF-at

85 Rab6 loss-of-function inhibits retrograde Golgi trafficking, induces an increase in Gol

86 te PHC (<=20 ms ahead of the His) due to the retrograde His conduction time.

87 stsynaptic compartment necessary to generate retrograde homeostatic signaling.

88 sults confirm the retromer-mediated model of retrograde HPV entry and validate intracellular virus tr

89 ilia disassembly, shortened primary cilia, a retrograde IFT defect for IFT and BBS proteins, and redu

90 nt requires cytoplasmic microtubules and the retrograde IFT motor, dynein 1b [14].

91 leaving the cilium, but not in activation of retrograde IFT.

92 vides insights into the pathways for tRNAPhe retrograde import and re-export and is a tool that can b

93 revealed that the karyopherin Mtr10 mediates retrograde import of tRNAPhe, constitutively and in resp

94 with cell type specific promoters to target retrograde infection of pseudotyped and genetically modi

95 stand the underlying circuitry, we performed retrograde injections of modified rabies virus in the vi

96 Further, these data support the retrograde inoculation hypothesis, whereby the infant or

97 ectivity, substantially more anterograde and retrograde label was present in the hemisphere ipsilater

98 licited by psychostimulants, the position of retrograde-labeled neurons stained by injections into th

99 Retrograde labeling from the colon showed that NG and TL

100 Combined cfos imaging and retrograde labeling in dopamine transporter (DAT) Cre mi

101 ) into the NTS produces a similar pattern of retrograde labeling in rats and mice.

102 Retrograde labeling of AT(2)R-eGFP(+) neurons projecting

103 Similar patterns of retrograde labeling result from tracer injections into d

104 Retrograde labeling studies in mice from the parabrachia

105 Using anterograde and retrograde labeling, we found that a sparse and relative

106 Retrograde labelling of bladder-projecting dorsal root g

107 nssynaptic viruses (PRV152) transported in a retrograde manner, the long-distance indirect projection

108 pears to be crucial for the establishment of retrograde membrane flow, because inhibition of endocyto

109 Here the retrograde membrane is, in itself, an anterograde carrie

110 Numerous mutations that impair retrograde membrane trafficking between endosomes and th

111 o prevent membrane mixing between ER and the retrograde membrane.

112 TANGO1 corrals retrograde membranes at ER exit sites to create an expor

113 productive age, and is thought to arise from retrograde menstruation and implantation of endometrial

114 indings establish a key role of a plastidial retrograde metabolite in orchestrating the transduction

115 th a TRM phenotype that nevertheless undergo retrograde migration, yet remain durably committed to th

116 LN via the lymphatic vessels, which we term retrograde migration.

117 Disrupting retrograde mitochondrial flux in neurons leads to accumu

118 er, our work shows the conserved reliance on retrograde mitochondrial transport for maintaining a hea

119 Disrupting retrograde mitochondrial transport impacts the homeostat

120 he mean frequency, velocity, and distance of retrograde mitochondrial transport in the adjacent axon.

121 supports a previously unappreciated role for retrograde mitochondrial transport in the maintenance of

122 nsistent with this, we provide evidence that retrograde mitochondrial transport is important for remo

123 ime spent in anterograde motion was reduced; retrograde motion was spared.

124 coupling organelles to the microtubule (MT) retrograde motor dynein-dynactin.

125 sts of the anterograde motor kinesin-II, the retrograde motor IFT dynein, and the IFT-A and -B comple

126 tering proximal to nuclear lamina folds, and retrograde movement of actin bundles that correlated wit

127 accumulation at the immunological synapse to retrograde movement toward the distal end of the T cell

128 n sympathetic neurons that was essential for retrograde nerve growth factor (NGF) signaling and neuro

129 Retrograde neural tracers were injected in different par

130 Anterograde and retrograde neuroanatomical tracing confirmed the connect

131 eparate cohort of animals were injected with retrograde neuronal tracer (DiI) and dye uptake in nodos

132 To investigate this, we injected retrograde neuronal tracers occupying the whole visuotop

133 These results suggest that regulation of retrograde NGF signaling in sympathetic neurons by Elp1

134 revisiae to identify proteins mediating tRNA retrograde nuclear import and re-export using the unique

135 evolutionarily conserved process called tRNA retrograde nuclear import, before relocalization back to

136 r the directionality of the Mla system being retrograde (OM to IM) or anterograde (IM to OM).

137 Here, we placed injections of retrograde or anterograde tracers into LDTg, LHb, IP, an

138 y that requires the Rcy1 F-box protein and a retrograde pathway originating from the multivesicular/p

139 There is a link between PAP/SAL retrograde pathway, ethylene signaling and Fe metabolism

140 m in three different mutants of the PAP/SAL1 retrograde pathway.

141 Retrograde peri-implantitis (RPI) is a rapidly progressi

142 symmetrical Gram-negative outer membrane via retrograde phospholipid transport.

143 Retrograde polysynaptic neuronal tracing from the intest

144 f elevated extracellular K(+) and initiate a retrograde, propagating, hyperpolarizing signal that dil

145 eases, and mutations of the Golgi-associated retrograde protein (GARP) complex cause progressive cere

146 or function of the related Golgi-associated retrograde protein (GARP) complex.

147 (2) treatment inhibited both anterograde and retrograde protein transport, consistent with the loss o

148 y of newborn Tau(VLW) DGCs, and monosynaptic retrograde rabies virus tracing showed that these cells

149 se and a transcriptional corepressor enables retrograde regulation by vPK of ZEBRA, an observation th

150 nating post-and pre-synaptic strength, using retrograde regulation of axonal actin dynamics to mobili

151 uli to optimize growth via the mitochondrial retrograde response signaling pathway.

152 entified as a regulator of the mitochondrial retrograde response.

153 , and suggest a critical role for long-range retrograde Ret signaling in regulating growth cone dynam

154 ted Ret in pioneer growth cones, and reduced retrograde Ret51 transport.

155 hing their intracellular trafficking via the retrograde route, from early endosomes to the Golgi appa

156 llows the texture of the substrate, creating retrograde shear forces that are sufficient to drive the

157 013 and ANAC017, which mediate a ROS-related retrograde signal originating from mitochondrial complex

158 sitivity to neurotransmitter and activates a retrograde signal that restores synaptic function by adj

159 We attributed this to a novel apocarotenoid retrograde signal, as chemical inhibition of carotenoid

160 The mitochondria-to-nucleus retrograde signaling (MtRS) pathway aids in cellular ada

161 trin, a key component of the MPS, suppresses retrograde signaling and protects axons against degenera

162 tmentalized at postsynaptic densities, gates retrograde signaling and provides an intriguing molecula

163 dy has identified pathological mitochondrial retrograde signaling as a disease modifier in primary an

164 eceptor dephosphorylation, which resulted in retrograde signaling failure and neuron death.

165 s well as heterosynaptic mechanisms, such as retrograde signaling from postsynaptic cholinergic and G

166 Previous studies on retrograde signaling have mainly analyzed the regulation

167 The plastidial retrograde signaling metabolite methylerythritol cyclodi

168 receptor phytochrome B (phyB) and plastidial retrograde signaling metabolite methylerythritol cyclodi

169 a recently identified class of mitochondrial retrograde signaling molecules and are reported to be po

170 abotropic glutamate receptor mGluR5 triggers retrograde signaling of endocannabinoids that activate p

171 e pancreatic cancer (Rip1-Tag2), mediated by retrograde signaling of transmembrane Sema4D in macropha

172 ive phosphorylation genes, trigger a ROS-JNK retrograde signaling pathway that drives CCF formation a

173 outline an extended mitochondria-to-nucleus retrograde signaling pathway that initiates formation of

174 egulated plastid-to-nucleus communication by retrograde signaling pathways is essential for fine-tuni

175 but how activity engages and maintains this retrograde signaling system is not well understood.

176 tion with the endoplasmic reticulum, and how retrograde signaling upregulates the mitochondrial stres

177 tant for axon integrity and for axon-to-soma retrograde signaling, a process critical for axon develo

178 in the absence of Elp1 rescued NGF-dependent retrograde signaling, and in an animal model of FD it re

179 ved in synaptic targeting and morphogenesis, retrograde signaling, and neuronal survival.

180 We also discuss emerging concepts including retrograde signaling, approaches to mapping these networ

181 and posttranslational regulation to plastid retrograde signaling, we combined label-free proteomics

182 or mutant affected in chloroplast-to-nucleus retrograde signaling-as the first known component in cpU

183 ted signaling, innate immune activation, and retrograde signaling.

184 lasts and suggests that MORF2 is involved in retrograde signaling.

185 tional responses of markers of mitochondrial retrograde signaling.

186 oroplast biology, including the discovery of retrograde signaling.

187 with the plastid gene expression pathway of retrograde signaling.

188 ge number of nuclear genes, a process called retrograde signaling.

189 nism by which palmitoylation controls axonal retrograde signaling.

190 Retrograde signals contribute to circadian timing 1750 I

191 ne expression is regulated by a diversity of retrograde signals that travel from organelles to the nu

192 ne expression in response to plastid-derived retrograde signals.

193 olecular level the origin of the lowered and retrograde solubility of the protein.

194 of the transmembrane lysine residues ablate retrograde sorting and subject Snc1 to quality control v

195 plex connection with Rab7a, which blocks the retrograde sorting of Cation-independent Mannose 6-Phosp

196 and defines a role for CHC22 in addition to retrograde sorting of GLUT4 after endocytic recapture, e

197 radation as well as enzyme susceptibility of retrograded starch was explored.

198 ore ordered physical structure in native and retrograded starches.

199 igher resistance to enzyme hydrolysis of the retrograded starches.

200 Retrograde sterol internalization to STRIC is independen

201 replacement) were shorter, compared with the retrograde technique in the LAMPOON investigational devi

202 uring the relapse test by using Fos plus the retrograde tracer cholera toxin B (injected into the OFC

203 Retrograde tracer Fluoro-Gold injected into the RTN labe

204 The retrograde tracer Fluorogold was injected into inferior

205 Injections of the retrograde tracer fragment B of cholera toxin (CTb) were

206 ce that allows exploration of results of 143 retrograde tracer injections in the marmoset neocortex.

207 e made small iontophoretic injections of the retrograde tracer microruby, targeted to the koniocellul

208 of the cholera toxin which is a monosynaptic retrograde tracer was used as a control to be able to di

209 aging and then injected fluorescently tagged retrograde tracers (cholera toxin subunit B) into retino

210 Injections of different retrograde tracers in each nucleus produced similar patt

211 Visceral afferents were back-labeled using retrograde tracers injected into proximal and distal reg

212 despite being extensively labeled by general retrograde tracers injected into the VTA.

213 We used double labeling with fluorescent retrograde tracers to identify individual IC cells that

214 ll, discrete coinjections of anterograde and retrograde tracers within the thalamus and cortex, our c

215 We found cells in the IC that contained both retrograde tracers, indicating that they project bilater

216 In the present study, we combined retrograde tracing and immunohistochemistry to examine t

217 We combined a viral retrograde tracing approach to map direct brainstem proj

218 Retrograde tracing from the dorsolateral striatum reveal

219 Combined with pseudorabies virus retrograde tracing from the iWAT, we defined the pregang

220 Rabies-mediated monosynaptic retrograde tracing identified the central nucleus of amy

221 Retrograde tracing in adult male rats (Rattus norvegicus

222 modified rabies virus-mediated monosynaptic retrograde tracing method to interrogate presynaptic int

223 Retrograde tracing plus triple-label immunofluorescence

224 s into different NTS subdivisions, with dual retrograde tracing revealing that many afferent neurons

225 Retrograde tracing showed extensive direct projections f

226 Retrograde tracing showed that NPY neurons are principal

227 port, we implemented in vivo anterograde and retrograde tracing techniques aiming to elucidate the or

228 al cortex was analyzed using anterograde and retrograde tracing techniques.

229 ical pharmacology, immunohistochemistry, and retrograde tracing to demonstrate a critical role of the

230 Retrograde tracing using cholera toxin beta (CTB) in the

231 Retrograde tracing using indocarbocyanine dye (DiI) reve

232 Using multicolor retrograde tracing we determined the density, topography

233 Here we use retrograde tracing with cholera toxin subunit b to show

234 Retrograde tracing with fluorescent cholera toxin subuni

235 Here, we combined retrograde tracing with immunocytochemistry against tyro

236 enotype of LDTg afferents to IP by combining retrograde tracing with immunofluorescence and in situ h

237 For this, we combined anterograde and retrograde tracing with immunohistochemical approaches t

238 We combined retrograde tracing with single-unit recording and labell

239 cell transcriptional profiling, monosynaptic retrograde tracing, and multiplexed FISH to characterize

240 Next, we used retrograde tracing, chemogenetic, and electrophysiologic

241 otometry, chemo/optogenetics, virus-assisted retrograde tracing, ChR2-assisted circuit mapping and be

242 Here, we combine birth-dating analysis, retrograde tracing, gene overexpression and knockdown, a

243 lateral geniculate nucleus were confirmed by retrograde tracing, suggesting they contribute to patter

244 Here, using retrograde tracing, we demonstrate differences in the di

245 Using retrograde tracing, we found LJA5 neurons receive inputs

246 To study this, we used trans-neuronal viral retrograde tract tracing, using isogenic strains of pseu

247 ory/regulatory proteins of retromer-mediated retrograde trafficking from endosomes.

248 n 1 (COPI)-vesicle coatomer, which regulates retrograde trafficking of cargo between the Golgi appara

249 This internalization is followed by retrograde trafficking of CFTR to the endoplasmic reticu

250 Therefore, retromer does contribute to the retrograde trafficking of CI-M6PR required for maturatio

251 ther, our work explains how Retro-2 prevents retrograde trafficking of toxins by inhibiting TA-protei

252 We used a retrograde trans-synaptic rabies virus system to generat

253 lular structures involved in anterograde and retrograde transmission and suggest a key role for DCs i

254 Here, we used retrograde transneuronal transport of rabies virus to id

255 isiae golgin Coy1 contributes to intra-Golgi retrograde transport and binds to the conserved oligomer

256 in-BicD2, the dynactin p150 subunit promotes retrograde transport and could serve as a target for reg

257 f TMEM16K function led to impaired endosomal retrograde transport and neuromuscular function, one of

258 tlas of the brain, although its capacity for retrograde transport currently limits its use to unidire

259 Thm1-mutant cilia also show a retrograde transport defect for the Hedgehog transducer,

260 oat protein I (COPI)-coated vesicles mediate retrograde transport from the Golgi to the endoplasmic r

261 tidylinositol-3,5-bisphosphate synthesis and retrograde transport from the vacuole.

262 o, a new capsid variant capable of efficient retrograde transport in brain, was generated in mice usi

263 for trans-Golgi network (TGN) functions and retrograde transport in HSV entry.

264 Our results suggest that Golgi to ER retrograde transport may be important under conditions o

265 Together, these studies demonstrate strong retrograde transport of AAV2.retro in NHP brain, highlig

266 1 (dynein) is the motor responsible for most retrograde transport of cargoes along microtubules in eu

267 We show that retrograde transport of mitochondria from axon terminals

268 TRIM46-labeled microtubules drive retrograde transport of Neurofascin-186 to the proximal

269 hat the dynein adaptor RILP is essential for retrograde transport of neuronal autophagosomes, and sur

270 Retrograde transport of this organelle has been implicat

271 , including effecting nuclear migration, and retrograde transport of various cargos.

272 Ypt6 is critical for the retrograde transport of vesicles from endosomes to the t

273 cell body, the precise impact of disrupting retrograde transport on the organelles and the axon was

274 protein and sorts incoming virions into the retrograde transport pathway for trafficking to the nucl

275 or Rab11 GTPases, which are involved in the retrograde transport pathway, resulted in only a slight

276 he processes of autophagosome biogenesis and retrograde transport to control autophagic turnover.

277 of endosomal trafficking pathways including retrograde transport to the trans-Golgi network (TGN), i

278 on, we adopted moss kinesin-14 for efficient retrograde transport with minimal adverse effects on end

279 autophagosomes undergo UNC-16/JIP3-mediated retrograde transport, and that autophagosomes containing

280 kely promotes coat protein complexI-mediated retrograde transport, thus maintaining the steady-state

281 de from the cis-Golgi to the ER through COPI retrograde transport.

282 (TA) proteins, including SNAREs required for retrograde transport.

283 while they bud, thereby promoting efficient retrograde transport.

284 isease etiologies within the KDELR-family of retrograde transporters.

285 sted the model that transcription results in retrograde transposition of nucleosomes along a transcri

286 and for mapping inputs to such neurons using retrograde transsynaptic tracing with modified rabies vi

287 um-Activated Tracer), a genetically encoded, retrograde, transsynaptic labeling system.

288 Stress is known to induce retrograde tRNA translocation from the cytoplasm to the

289 n functional experiments, another virus with retrograde tropism, a canine adenovirus expressing Cre r

290 nism of action (MOA), which involves halting retrograde vesicle transport to the endoplasmic reticulu

291 We show that anterograde or retrograde vesicular transports are asymptotic behaviors

292 Using a retrograde viral labeling technique and real-time monito

293 In a separate experiment, retrograde viral tracers were used to examine connection

294 primer on currently applied anterograde and retrograde viral tracers with practical guidance on expe

295 method, termed "Connect-seq," which combines retrograde viral tracing and single-cell transcriptomics

296 Furthermore, retrograde viral tracing from muscles that control orofa

297 ible Rosa-eGFP-L10a mice in combination with retrograde viral tracing to identify circuits was used t

298 AV8-DIO-hM(4)Di into the LHb and CAV2-CRE (a retrograde viral vector) into one of the three target ar

299 eated with antegrade wire escalation (N=90), retrograde wire escalation (N=24), ADR (N=35), and retro

300 compared between antegrade wire escalation, retrograde wire escalation, antegrade dissection and ree