ライフサイエンスコーパス: reveal

1 enetic analysis and gene inactivation tests, revealed 19 new cases of genes whose integrity is regula

2 Phylogenetic analysis revealed 20 OsPLDalpha1 cDNA variants which further tran

3 LostArc reveals 35 million deletions (~ 470,000 unique spans) in

4 Atomic force microscopy revealed 40-300 nm diameter OMVs from control and stress

5 This revealed 44,652 high-quality viral genomes (that is, >90

6 Host & Microbe, Guo, Kasahara et al. (2020) reveal a critical role for pDCs in antifungal immunity.

7 stal structures of arsenic-bound p53 mutants reveal a cryptic allosteric site involving three arsenic

8 We reveal a detailed and quantitative map of the features o

9 molecular dynamics simulation approaches to reveal a detailed mechanism.

10 -EM structures in the open and closed states reveal a dynamic tunnel lining, with implications for ga

11 We reveal a gating mechanism that involves two ion-conducti

12 Taken together, our findings reveal a key role and an epigenetic mechanism of action

13 The results reveal a local role for CEPR1 in the maternal reproducti

14 Our results reveal a mechanism by which satellite repeats regulate g

15 Jellyfish genomes reveal a mosaic of conserved and divergent genomic chara

16 o oligodendrocyte development and repair and reveal a new role for Nedd4 in glial biology.

17 n elements of transpeptidase substrates, (b) reveal a novel mechanism of stereochemical editing withi

18 The results reveal a paradoxical acetylation-mediated molecular clut

19 major disruptions in chromatin structure and reveal a role for Suv39h2 in depositing sufficient H3K9m

20 Patient specimens reveal a strong correlation between stromal CAF content

21 Our results reveal a surprising bidirectional regulation of molecula

22 Gene expression analyses of these plants reveal a trade-off between VTE and natural variation in

23 lts on the structure and activity of Lpg2603 reveal a unique mode of regulation of a protein kinase,

24 Our results, which further revealed a built-in mechanism controlling Gc membrane in

25 onformation capture (Hi-C)(1,2) analysis has revealed a complex genomic landscape of internal chromos

26 HPLC analysis revealed a decrease in carotenoid levels of the differen

27 Immunoblotting revealed a decrease of AQP5 protein abundance when each

28 Resistance mapping revealed a druggable site formed by the G protein fusion

29 Chemistry efforts on the scaffold revealed a dynamic structure activity relationship and d

30 structures of Saccharomyces cerevisiae Spf1 revealed a large, membrane-accessible substrate-binding

31 d; however, preclinical and clinical studies revealed a limited therapeutic time window and systemic

32 n remains unclear, and studies thus far have revealed a mixed pattern of results in support of either

33 Our study revealed a new mechanism by which platelets promote the

34 combined with electrophysiological tools, we revealed a population of glycinergic cells in the VCN di

35 Superresolution microscopy revealed a reduced interaction of CG with the microtubul

36 In vivo recordings revealed a strong role for hAPP/Abeta, but not tau, in t

37 NAcC neuronal recordings revealed a stronger representation of incentive than ins

38 Cryo-EM of the NTD dimer revealed a structural similarity to the scaffold domain

39 This study revealed a total of 33 brain neuropils and 30 neuronal f

40 density waves as being Fermi surface-driven, revealing a novel ordering mechanism in this nickelate t

41 5 +/- 0.02, and 0.20 +/- 0.05, respectively, revealing a V-shaped SF/RH dependence.

42 The structure reveals a composite binding site bridging over three dom

43 ctural analysis of the MvcA-UBE2N-Ub complex reveals a crucial role of the insertion domain in MvcA i

44 Despite the fact that this reveals a mechanism by which evolution could drive a pat

45 This work reveals a paracrine mechanism of antiandrogen resistance

46 Our study reveals a previously undiscovered Lyn-dependent exit rou

47 Cell-specific deletion reveals a requirement for GATA6 in various SAN lineages.

48 This study reveals a striking zonal architecture for the transition

49 Genome-wide transcriptomic analyses have revealed abundant expressed short open reading frames (O

50 homologs in C. elegans and other animals may reveal additional new compound families and signaling pa

51 nexplained recurrent respiratory infections, revealing age-dependent variation and suggesting a role

52 FTIR studies revealed alterations in protein secondary structure indu

53 Further, RNA sequencing analysis revealed altered gene expression in Tph1 deficient ILC2s

54 oss hundreds of thousands of yeast cells and reveals ample evidence of both vertical and horizontal p

55 ide dependence of mHsp60 ring formation, and reveal an inter-ring nucleotide symmetry consistent with

56 for the acute O(2) regulation of breathing, reveal an unanticipated role of HIF2alpha, and link acut

57 These findings reveal an unexpected aspect of theta-based hippocampal e

58 Pulses of FDAA labeling revealed an arrangement of separate regularly spaced "no

59 Imaging revealed an atypical form of rhombencephalosynapsis, a d

60 Meta-regression revealed an increase in Anisakis spp. abundance (average

61 adhesion-related proteins in SW480+APC cells revealed an increase in p120-catenin isoform 3A; similar

62 OSAS patients revealed an increased PD-1 and PD-L1 expression in T cel

63 Methane production reveals an additional bacterial pathway distinct from ar

64 ations, both primary and cultured, typically reveals an intercellular variability in migration speeds

65 Taken together, our study reveals an unexpected isoform diversity of MYO7A express

66 Together, our results reveal anatomic control of NK cell development and maint

67 n solvents by an eco-friendly procedure were revealed as a source of compounds with relevant antioxid

68 Modeling revealed attenuated directed exploration under L-dopa, w

69 herapy prevented a 1-month-of-life loss, and revealed bevacizumab, ranibizumab, and aflibercept confe

70 y faster decrease of the CNV lesion size, as revealed by in vivo imaging and immunohistochemistry fro

71 impeded DNA replication across the genome as revealed by microfluidic-assisted replication track anal

72 terization of the turnover chemistry of Pgp3 reveals cell wall D,D-endopeptidase and D,D-carboxypepti

73 vice (Atcor Medical Sphygmocor XCEL) (n = 5) revealed central aortic systolic pulse (CASP) and centra

74 m of a foot amputated from an affected child revealed complete absence of skeletal muscle (i.e., segm

75 e chromatin interaction mapping, using Hi-C, reveals condensin-mediated chromatin interactions in int

76 Previous studies have revealed consistent suppression of predicted stimulus in

77 oband-parent trios, and case-control cohorts revealed defects in cardiomyopathy-associated genes in p

78 Purification and identification revealed deleted in malignant brain tumors 1 (DMBT1) (al

79 Moreover, human cohort data have revealed differential DNA methylation signatures in prox

80 blot monitoring of teichoic acid production revealed differential patterns in response to each inhib

81 itation (HITS-CLIP) and biochemical analyses revealed direct binding between endogenous TruB1 and the

82 s in both disease states, but the metabolome reveals disease-specific patterns.

83 solution analyses of these two types of QTLs reveal distinct positions of enrichment at the central t

84 patterns in conventional monocytes and pMos revealed distinct baseline signaling profiles and far gr

85 Our systematic and comprehensive analyses revealed distinct genetic architecture of human NP and A

86 The study also revealed distinct parallels to photoredox-catalyzed reac

87 nm and with a spatial resolution ca. 5 nm to reveal domain morphology and distribution.

88 ith PTOA treated with liposomal A2AR agonist revealed downregulation of genes associated with matrix

89 Both basic and clinical evidence reveal dual roles for GJs, in tumor suppression, general

90 Our data reveal effector-triggered and phosphorylation-regulated

91 olonic crypts isolated from CR-infected mice revealed elevated levels of LRP5/6 and FZD10 and beta-ca

92 gression around the 90-minute cutoff did not reveal evidence of a significant discontinuity (P=0.66).

93 We again reveal favorable results, particularly in extracting win

94 These findings reveal for the first time, to our knowledge, the dynamic

95 nctional aspects of sour cherry vinegar were revealed for the first time.

96 Proteomics data further reveal functional effects of somatic mutations and copy

97 f the produced compounds is of importance to reveal functional interactions in microbiomes.

98 the principled physics of driving forces and reveals granular detail of conformational populations in

99 The immunologic study revealed high titers of IgG autoantibodies in serum and

100 kinetic control with highly viscous FIL/ILs, revealing higher performance differences between FIL/IL

101 of the largest ubiquitin ligase subtype and reveal how a defined architecture within a disordered re

102 These findings reveal how an interaction between cells in different EMT

103 microscopy and density functional theory to reveal how the generation of S-vacancies within MoS(2) n

104 BP membrane in osmotic energy conversion and reveal how the oxidation of BP influences power generati

105 atomic structures of Abeta oligomers, which reveal how they form lipid-stabilized pores that might d

106 A new study reveals how differences in tubulin populations between t

107 of the FigC N-citrylornithine decarboxylase reveals how the larger substrate is accommodated and how

108 Cryo-ET reveals how the shape of the helical membrane tube arise

109 Particularly, our results revealed IGFALS as a useful biomarker for moderate-sever

110 Post-FUS contrast MRI revealed immediate and sizable hippocampal parenchymal e

111 Superresolution microscopy revealed in infected cells the vertical displacement of

112 Our findings reveal increased oscillatory activity in the beta band (

113 ion using a hippocampal computational model, revealing increased representational dissimilarity for u

114 research on NF-kappaB in invertebrates will reveal information about the evolutionary roots of this

115 trol of gut bacterial metabolism in order to reveal its local and systemic effects on host health and

116 pe, including its endocast and inner ear, to reveal its morphology for the first time.

117 Paired TCRalphabeta analyses of MAIT cells revealed large clonal expansions in older adults and tis

118 At admission, laboratory studies revealed leukocytosis, with a white blood cell count of

119 Previous studies revealed maize and mixed-food refuse at both sites, but

120 Histological examinations did not reveal major structural changes at proximal sciatic nerv

121 Our results reveal malaria parasites are at least partly responsible

122 d rat models of cancer with a thermal camera reveals material heterogeneity and delineates diseased f

123 Travel history revealed multiple journeys to tropic and subtropic regio

124 saicin-mediated TRPV1 activation gating, and reveals multiple ligand-channel interactions that stabil

125 omosome conformation capture (Hi-C) analysis revealed multiplex, activated enhancer-promoter configur

126 e integrative disease-modelling strategy may reveal new insights into mechanisms of cardiac disease a

127 Our findings reveal new links between avian physiology, ecology, beha

128 ting fundamental properties of lncRNA genes, revealing new insights into the RNA structure-function r

129 ta and BCAR episodes from all six CTG trials revealed no safety concerns when compared with the RGT.

130 ve that utilizing registries and biobanks to reveal other monogenic atypical forms of diabetes is an

131 he study of familial autoimmune diseases can reveal pathophysiological mechanisms involved in more co

132 ients according to their PK parameter values revealed patient subgroups for each drug in which inter-

133 Our experiments revealed PLD3 as the principal acid 5' exonuclease in He

134 with multiple nuclear RNA binding proteins, revealing preferential colocalization of subsets of fact

135 Domain swap chimeras also revealed previously unknown functional differences in th

136 The constitutive equation also reveals previously unknown ballistic and diffusive limit

137 protein complexes in a membrane environment, revealing putative sites for conformational switching.

138 The core disease signature revealed remarkably strong connections to genes with est

139 rected mutagenesis of both cofilin and actin revealed residues critical for sustaining or abrogating

140 racterization of OFF-RGC terminals in tectum revealed responses that varied in their photosensitiviti

141 Mean-field analysis and computer simulation reveal rich phase behavior for this simple model, featur

142 nscriptome analysis of Hh-deficient mesoderm revealed selective deficits in anterior mesoderm populat

143 Metagenomic analysis did not reveal significant differences in taxonomic or functiona

144 s results, our transcriptomics analyses also revealed significant alterations in gene expression leve

145 The SPECT/CT and basic fuchsin staining revealed significant higher-density spatial accumulation

146 Mosaic knockout of either PKS or GCM revealed spatial lineage commitment in the transition fr

147 Electron tomography unexpectedly revealed spermatocyte anaphase A does not stem solely fr

148 review of the manufacturer's training video revealed sterility breaches in contrast preparation.

149 Different diagnostic ratios revealed sterols originating from human and nonhuman sew

150 We use genomic profiling to reveal strong and broad loss of neural APA in elav/fne d

151 Field experiments revealed strong broad- and narrow-sense trait heritabili

152 hat IrtAB has an ABC exporter fold, but also reveals structural peculiarities at the transmembrane re

153 They also reveal stunning differences between compensatory process

154 hate crime perceptions can be purposive and reveal supremacist sympathies.

155 These results reveal that 5' auto-processing of progenitor sgRNAs occu

156 In current research, we reveal that a dendronized polymer augments the efficacy

157 resonance, and NMR spectroscopy experiments reveal that a disorder-to-order transition of the ankyri

158 reveal that a gain-of-function JAK1 genetic variant resu

159 These results reveal that ACC is a critical node in model-based contro

160 Our findings reveal that accessibility to all positions tested is mod

161 These findings reveal that aerobic glycolysis is a process functionally

162 Cell surface-based loss-of-function screens reveal that ATP7A, a copper-exporter upregulated by muta

163 Here we reveal that BRs also participate in the control of ovule

164 c and aromatic archetypes, respectively, and reveal that CBD fulfills the criteria on the state order

165 reveal that excessive placental DNA damage in murine mod

166 Mass spectrometry analyses reveal that HIPK2 is at least O-GlcNAc modified at S852,

167 ar dynamics simulations and studies in cells reveal that LD targeting of these motifs requires deeply

168 Together, these data reveal that liver sinusoidal endothelial cells sense the

169 Recent experiments reveal that micro-structured tungsten can exhibit signif

170 Our analyses reveal that not all traits are equally well-suited for r

171 Experimental data reveal that the CIE coordinates within the studied serie

172 e feed with low surface tension, experiments reveal that the number of polyelectrolyte layers, rather

173 Mutagenesis studies reveal that the region D1 in p27 plays a significant rol

174 We reveal that the SARS-CoV-2 virus becomes more infectious

175 Phylogenetic analyses reveal that these form-function associations reflect con

176 Furthermore, our findings revealed that 3 mo of OLT1177 diet can rescue synaptic p

177 different functional modules of the network revealed that 76% of the genes and all gene modules part

178 Our analysis revealed that 82% of real-world examples of climate chan

179 rray analysis and single-cell RNA sequencing revealed that a number of cytokine-inducible genes share

180 However, the optimal models revealed that both the density of eels and the number of

181 Our analysis of other oomycete genomes revealed that both uridine phosphorylases are present in

182 c and chromatin immunoprecipitation analysis revealed that CDK8 positively regulates the transcriptio

183 DynaFit revealed that cell fitness in cancer cell lines, primary

184 diffraction and inelastic neutron scattering revealed that confined nickel(II) sites enabled chemosel

185 In vivo calcium imaging revealed that different GA drugs activate a shared ensem

186 Reconstruction of the 3D nucleus revealed that distances of the homologous chromosomes to

187 Computational modeling revealed that dominant learning mechanisms underpinning

188 ar-producing accessions of Solanum pennellii revealed that expression levels of known and novel candi

189 An investigation into barrier proteins revealed that heme primarily affected the tight junction

190 The present findings also revealed that high doses of BrdU lead to the activation

191 Chemical screening revealed that inhibition of MEK/ERK signaling overcame t

192 Further analysis and in vitro validation revealed that metformin optimally reverts diabetogenic g

193 Atomic force microscopy revealed that MFS CMs are stiffer compared to corrected

194 Finally, microscopy-based metabolic analysis revealed that migratory cells selectively utilize oxidat

195 Microarray analysis of ventricular tissue revealed that miR-21 and miR-221, 2 activators of profib

196 s in genetic and proteomic technologies have revealed that more of the genome encodes proteins than o

197 A sample-to-sample matrix revealed that MPS populations could be separated based u

198 Our data analysis revealed that multiple biological processes including tr

199 2D and 3D co-cultures of NHFs and PDAC cells revealed that older NHFs stimulate proliferation of and

200 Our results revealed that over-expressing CENH3 in callus is lethal

201 miR-21 expression in the TCGA glioma dataset revealed that overexpression of miR-21 was a potential i

202 s spectrometry of polished flat ore surfaces revealed that P. glomerata could effect changes in Se/Te

203 m20C itself in OPN phosphorylation, but also revealed that phosphorylation was essential for OPN secr

204 Computational analysis revealed that reward led to both an increase in feedback

205 Furthermore, Raman spectroscopy results revealed that the 9th-week GBs has a fine and strong MB

206 Cosedimentation experiments with liposomes revealed that the Aster-B GRAM domain binds to membranes

207 Indirect calorimetry analyses revealed that the deletion of ALX dysregulated energy me

208 Recent studies have revealed that the failure of proteostasis with age is tr

209 ing-state functional MRI (fMRI) studies have revealed that the global signal (GS) exhibits a nonunifo

210 Our studies revealed that the interleukin-22 (IL-22)/IL-17-producing

211 Therefore, this study has structurally revealed that the niche is organized into multiple compa

212 An intention-to-treat analysis revealed that the proportion of participants commencing

213 In this study, we revealed that the specific DRs are involved in the produ

214 -specific smallest effect sizes of interest, revealed that the treatment effects observed in four out

215 itoring of CaCC activity and Ca(2+) dynamics revealed that the TRPV1 ligand capsaicin activated CaCCs

216 In vivo fiber photometry revealed that these neurons are selectively excited by t

217 Theoretical modeling revealed that these regulatory strategies (bursting and

218 nvolution of the PC1 top-correlated segments revealed that these segments are comprised of methylatio

219 WGS revealed that this prevalence was not due to clonal spre

220 Desorption and regeneration experiments revealed that TLSB could be desorbed with HCl to recover

221 Morphometric analyses revealed that Treg depletion blocked plaque remodeling a

222 X-ray diffraction, and gelatinization assays revealed that ultrasound treatment induced changes in gr

223 mission and transient absorption experiments revealed that upon excitation, our multichromophoric rot

224 Phylogenetic analyses revealed that while a few genes cluster with those of ot

225 systematic studies of these interactions are revealing that proteins may exhibit different binding mo

226 pressed with a P. marinus sulfite reductase, revealing that pssm2-Fd can transfer electrons to a host

227 Analysis of this dataset reveals that a soil area of 11.73 Mkm(2) located in nonf

228 Our study reveals that ad hoc or experience-based flow management

229 oss-sectional cohort of CHIKV-deaths to date reveals that CHIKV-ECSA strains can cause death in indiv

230 Metabolomic analysis reveals that dietary uptake of glutamine effectively inc

231 The structure reveals that FlhB/SctU extends the helical export gate w

232 A click chemistry-based flux assay reveals that necrocytosis provides not only amino acids,

233 Analysis of downstream effectors reveals that Nfatc1 promotes the expression of twist1b-a

234 QUAD analysis reveals that protein stability varied within tissues, bu

235 specific Tet2 deletion mouse model, the data reveals that TET2 plays a pivotal role in mammary gland

236 Photochemical cross-linking reveals that the baboon amylin, like human amylin, forms

237 Overall, this study reveals that the choice of EV isolation procedure signif

238 Exploration of the potential energy surface reveals that the cyclization step is a key step controll

239 Holding m = 1, spectroscopy reveals that the n = 1 superlattice contains Ni(3+) and

240 This structure reveals that two Rab33B molecules bind to the diverging

241 In this review, we reveal the basic principles of oral bacterial delivery,

242 er than to the plasma membrane, our findings reveal the complexity of recruitment mechanisms that nee

243 c stem cells with quantitative proteomics to reveal the dynamics and specificity of Parkin-dependent

244 Our findings reveal the existence of an underlying adaptive codon-bas

245 Collectively, these data reveal the existence of parallel differentiation program

246 Together, our results reveal the fundamental mechanisms and constraints with w

247 intrajejunal, and intracolon inoculations to reveal the impact of the plasmid on chlamydial colonizat

248 Here, we reveal the importance of a mutation's collateral fitness

249 inding pathways of TSPO ligands, which could reveal the molecular interactions governing ligand resid

250 eractions characterized here comprehensively reveal the nature of SARAH domain-mediated complex forma

251 These analyses reveal the noncanonical nature of the transformations at

252 nts of full length p53 tetramers binding DNA reveal the parameters that define the stability of p53/D

253 proximant of the quasicrystal, Ta(21)Te(13), reveal the presence of symmetry-protected nodal crossing

254 Together these studies reveal the previously unrecognized conformational cycle

255 Thus, deep learning can reveal the regulatory syntax predictive of the full diff

256 e-cell mutation and phospho-protein analyses reveal the segregation of oncogenic STAT5 and ERK activa

257 These findings reveal the spatiotemporal evolution of vascular remodeli

258 Our data reveal the specific coupling between ENaC gamma-subunit

259 We conclude that transportation big data reveal the status of regional economic development and c

260 These results reveal the structural determinants of tip-link-mediated

261 ustify the evaluation of their mechanics and reveal the underlying physics responsible for their unus

262 gy-filtered transmission electron microscopy reveal the well-associated optical and electron signal a

263 The structure also revealed the arrangement of multiple forms of alpha- and

264 Phylogenetic analyses revealed the cryptic introduction of at least seven diff

265 to cognate and wobble codons on the ribosome revealed the disruption of a C(32-)A(38) cross-loop inte

266 encoding the small subunit ribosomal RNA has revealed the extensive diversity of bacterial life on ea

267 and transient gene knockdown into the system revealed the formation of invasive leader cells with upr

268 rom patients with type 2 diabetes (T2DM), we revealed the implication of LXR and Nox4 in the pathophy

269 screen for increased female chasing behavior revealed the involvement of another sexually dimorphic n

270 acillus subtilis, we identified factors that revealed the link between chromosome translocation and p

271 asmid propagation in healthcare settings and revealed the national distribution of the resistance-enc

272 Our study revealed the potential of a structural approach to infor

273 cific replacement of active-site amino acids revealed the presence of a water-coordinating aspartate

274 Atom probe tomography of these crystals revealed the presence of heterogeneous spatial sequences

275 Circular dichroism spectroscopy revealed the presence of largely disordered species and

276 formance of the metabolic fingerprinting and revealed the presence of metabolites with significant in

277 er, recent in vivo tracking experiments have revealed the presence of SSCs not only within the bone m

278 erarchical clustering of OMP occurrence data revealed the relevance of 11 most frequently detected OM

279 I and a soluble CA IX mimetic (CA IX-mimic), revealed the structural basis of this particular inhibit

280 Recordings from cell pairs revealed the synchronized occurrence of distinct groups

281 By revealing the structural mechanisms of SA perception by

282 In addition, magnetic force microscopy reveals the ability to tune DMI in a range that stabiliz

283 This work also reveals the actual charge density (over 4.0 mC m(-2)) in

284 imics tassel blasting and drought stress and reveals the genetic mechanisms underlying these processe

285 the nonlinear behavior encoded in our record reveals the key role that polar ice volume plays in the

286 This study reveals the potential for a bacterial symbiont's sRNAs n

287 on the propagation rate coefficient (k(p)), reveals the transition state barrier for polycarbonate f

288 w their synthesis is regulated is crucial to revealing these lipids' role in health and disease.

289 ule imaging of p44/p62 complexes without XPD reveals they bind to and randomly diffuse on DNA, howeve

290 cultured isolates and metagenomic datasets, revealing thousands of encoded antibiotics.

291 Collectively, our results revealed three signals associated with systemic sclerosi

292 omprehensive mapping of synaptic connections reveals three recurrent circuit modules engaged sequenti

293 This connection is revealed through a combination of scanning PTE and elect

294 The measurements reveal time profiles of dissolved O(2) in each sample vi

295 ind this photoelectron-induced reduction was revealed to be concentration-dependent interfacial chemi

296 Mechanistic studies are presented that reveal two mechanisms for C-H borylation, (i) electrophi

297 Functional magnetic resonance imaging (fMRI) revealed two distinct patterns of activity, one in anter

298 Surgical correlation (n = 4) revealed unusual yellow discoloration of the bowel (n =

299 omonic features, but quantitative assessment reveals variability and a normal mean rate of age-relate

300 y and highlight the role of alpha rhythms in revealing when and where different types of memories are