ライフサイエンスコーパス: rhadinovirus

1 which we have called RRV, for rhesus monkey rhadinovirus.

2 on manifested accelerated reactivation of RM rhadinovirus.

3 cells by KSHV and the related rhesus monkey rhadinovirus.

4 within the RV1 lineage of Old World primate rhadinoviruses.

5 The rhadinovirus 1 (RV1) lineage consists of human herpesvir

6 MneRV2 and RRV belong to the rhadinovirus 2 (RV2) rhadinovirus lineage of Old World p

7 Similar to other rhadinoviruses, alternative splicing, coupled with alter

8 We observed that ORF45s of rhesus rhadinovirus and herpesvirus saimiri are found exclusive

9 he related rhadinovirus TKs of rhesus monkey rhadinovirus and herpesvirus saimiri.

10 Herpesviral ORF57 (Rhadinovirus) and ICP27 (Simplexvirus) proteins both int

11 at the agent is a gamma-2 herpesvirus (genus Rhadinovirus) and is the first member of this genus know

12 s conserved among the gamma-2-herpesviruses (rhadinoviruses) and, in Kaposi's sarcoma-associated herp

13 Nine rhadinovirus antibody-negative and two rhadinovirus anti

14 Nine rhadinovirus antibody-negative and two rhadinovirus antibody-positive monkeys were used for the

15 ng antibodies that recognize KSHV or macaque rhadinovirus antigens.

16 s (Rev of SIV and ORF57 of the rhesus monkey rhadinovirus) are dependent on the nature of the skewed

17 This comparison provides insight into RV2 rhadinovirus biology and sets the groundwork for more in

18 a potential role for this unusual protein in rhadinovirus biology and suggest that gammaHV68 will be

19 macaques as an important model for studying rhadinovirus biology, transmission and pathology.

20 s baboons as a novel resource to investigate rhadinovirus biology, which can be developed into an ani

21 ORF75 homologs are conserved in all rhadinoviruses but so far have no assigned functions.

22 irus (RRV) is a primate gamma-2 herpesvirus (rhadinovirus) closely related to Kaposi sarcoma-associat

23 and to uncover how the lymphocryptovirus and rhadinovirus enzymes differ, the subcellular localizatio

24 ction by members of the gamma-2 herpesvirus (rhadinovirus) family.

25 logenetic trees constructed with our macaque rhadinovirus gB sequences and those derived from additio

26 The eight macaque rhadinovirus gB sequences were all approximately equidis

27 RNA repertoires in the Lymphocryptovirus and Rhadinovirus genera of gammaherpesviruses and provide ev

28 ls, which have added to our knowledge of RV2 rhadinovirus genetics.

29 s in RRV17577 that were not present in other rhadinovirus genomes, including an N-terminal duplicatio

30 mmaherpesvirus 68 (MHV68) are members of the Rhadinovirus genus of gammaherpesviruses.

31 functional protein encoded by members of the Rhadinovirus genus of gammaherpesviruses.

32 letely sequenced and the first sequenced RV1 rhadinovirus homolog of KSHV from a nonhuman Old World p

33 n model for the murid herpesvirus 68 (MHV68) rhadinovirus identified a cluster of circRNAs near an MH

34 The recognition of naturally occurring rhadinoviruses in macaque monkeys has spurred interest i

35 esence of two distinct lineages of KSHV-like rhadinoviruses in Old World primates.

36 To further study the role of rhadinoviruses in the development of lymphoma, we sequen

37 and divergent functions of LANA homologs in Rhadinovirus infection and disease.

38 nsight into the roles of viral miRNAs during rhadinovirus infection and provides an important step to

39 To investigate gM and gN in rhadinovirus infection, we utilized infectious and patho

40 This simian rhadinovirus is genetically similar to a recently descri

41 mestrina) were inoculated intravenously with rhadinovirus isolates derived from these species (rhesus

42 e results demonstrate a close relatedness of rhadinovirus isolates from different macaque species.

43 ships of gB sequences from eight independent rhadinovirus isolates obtained from three species: rhesu

44 Japanese macaque rhadinovirus (JMRV) is a novel gamma-2 herpesvirus that

45 Japanese macaque (JM) rhadinovirus (JMRV) is a novel, gamma-2 herpesvirus that

46 sus rhadinovirus [RRV], and Japanese macaque rhadinovirus [JMRV]), closely related to EBV and KSHV, u

47 maherpesviruses and, specifically, the human rhadinovirus,KSHV.

48 K served alternate functions relevant to the rhadinovirus life cycle and to reveal the contribution o

49 of these viral species within the same RV-1 rhadinovirus lineage and the hypothesis that RFHV is the

50 The first rhadinovirus lineage consists of KSHV and its closely re

51 The RV2 rhadinovirus lineage is distinct and consists of closely

52 2 and RRV belong to the rhadinovirus 2 (RV2) rhadinovirus lineage of Old World primates and are disti

53 SHV-like herpesvirus belonging to the second rhadinovirus lineage.

54 Two rhadinovirus lineages have been identified in Old World

55 e determined that the pig-tailed macaque RV2 rhadinovirus, MneRV2, is highly associated with lymphoma

56 it is useful to investigate closely related rhadinoviruses naturally occurring in nonhuman primates.

57 ated herpesvirus (KSHV), and closely related rhadinoviruses of chimpanzees, gorillas, macaques and ot

58 Using degenerate PCR we identified a novel rhadinovirus, PapRV2, that has substantial sequence iden

59 ciated nuclear antigen (LANA) is a conserved Rhadinovirus protein that is necessary for long-term chr

60 es (rhesus rhadinovirus [RRV] and pig-tailed rhadinovirus [PRV]).

61 irus Peru (RHVP) is a recently characterized rhadinovirus related to murine gammaherpesvirus 68 (MHV6

62 (SIV) isolate SIVmac251 and macaque-derived rhadinovirus resulted in an attenuated antibody response

63 forms of the gamma-herpesvirus rhesus monkey rhadinovirus (rRRV) expressing a replication-incompetent

64 erpesvirus closely related to rhesus macaque rhadinovirus (RRV) and human herpesvirus 8.

65 cally similar to a recently described rhesus rhadinovirus (RRV) and is designated RRV 17577.

66 Herpesviruses, including rhesus monkey rhadinovirus (RRV) and its close homolog, the oncogenic

67 Rhesus monkey rhadinovirus (RRV) and Kaposi's sarcoma-associated herpe

68 ated gamma-2 herpesvirus rhesus macaque (RM) rhadinovirus (RRV) are the only known viruses to encode

69 KSHV) and the closely related rhesus macaque rhadinovirus (RRV) are the only viruses known to encode

70 KSHV) and the closely related rhesus macaque rhadinovirus (RRV) are unique for encoding viral homolog

71 vestigated whether recombinant rhesus monkey rhadinovirus (RRV) could be used as a vaccine against DE

72 Rhesus monkey rhadinovirus (RRV) exhibits high levels of sequence homo

73 mpetent, recombinant strain of rhesus monkey rhadinovirus (RRV) expressing the Gag protein of SIVmac2

74 the gH and gL glycoproteins of rhesus monkey rhadinovirus (RRV) following transient-transfection assa

75 The related rhesus monkey rhadinovirus (RRV) has shown potential as a vector to im

76 ma-68-herpesvirus (MHV-68) and rhesus monkey rhadinovirus (RRV) homologs can functionally substitute

77 Rhesus monkey rhadinovirus (RRV) is a close relative of Kaposi's sarco

78 Rhesus rhadinovirus (RRV) is a gamma-2 herpesvirus and is the r

79 Rhesus monkey rhadinovirus (RRV) is a gamma-2 herpesvirus that exhibit

80 Rhesus monkey rhadinovirus (RRV) is a gamma-2 herpesvirus that is most

81 Rhesus monkey rhadinovirus (RRV) is a gamma-2-herpesvirus that is clos

82 Rhesus rhadinovirus (RRV) is a gammaherpesvirus closely related

83 Rhesus macaque rhadinovirus (RRV) is a gammaherpesvirus of rhesus macaq

84 Rhesus monkey rhadinovirus (RRV) is a gammaherpesvirus that is closely

85 DNA sequence analysis indicates that rhesus rhadinovirus (RRV) is a member of the lymphotropic gamma

86 Rhesus macaque rhadinovirus (RRV) is a primate gamma-2 herpesvirus (rha

87 reat KSHV infection.IMPORTANCERhesus macaque rhadinovirus (RRV) is a rhesus macaque homolog of KSHV a

88 Rhesus macaque rhadinovirus (RRV) is closely related to Kaposi sarcoma-

89 Rhesus rhadinovirus (RRV) is closely related to Kaposi's sarcom

90 Rhesus monkey rhadinovirus (RRV) is one of the closest phylogenetic re

91 Rhesus macaque rhadinovirus (RRV) is the rhesus macaque homologue of hu

92 Rhesus macaque rhadinovirus (RRV) is the RV2 prototype, and two RRV iso

93 region L-DNA (L for low GC) of rhesus monkey rhadinovirus (RRV) isolate 26-95 was determined.

94 estigated the role of microtubules in rhesus rhadinovirus (RRV) nuclear trafficking in rhesus fibrobl

95 relative human herpesvirus 8, rhesus monkey rhadinovirus (RRV) persists predominantly in B cells of

96 ach, we obtained an infectious BAC of rhesus rhadinovirus (RRV) strain RRV26-95 with the BAC vector c

97 hed utilizing closely related rhesus macaque rhadinovirus (RRV) that naturally infects rhesus macaque

98 rains of replication-competent rhesus monkey rhadinovirus (RRV) were constructed in which strong prom

99 atory previously reported that rhesus monkey rhadinovirus (RRV), a close homolog of the human pathoge

100 we analyzed the composition of rhesus monkey rhadinovirus (RRV), a close phylogenetic relative of KSH

101 the expression of gH and gL of rhesus monkey rhadinovirus (RRV), a close relative of the human Kaposi

102 In rhesus monkey rhadinovirus (RRV), a close relative of the human oncoge

103 encoded by open reading frame R15 of rhesus rhadinovirus (RRV), a gammaherpesvirus closely related t

104 mbinant, replication-competent rhesus monkey rhadinovirus (RRV), a persisting herpesvirus.

105 Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely

106 VSV), adenovirus type 5 (Ad5), rhesus monkey rhadinovirus (RRV), and DNA again.

107 mmaherpesvirus 68 (MHV68) and Rhesus macaque rhadinovirus (RRV), and that the FHA domains of FOXK pro

108 ciated herpesvirus (KSHV) and rhesus macaque rhadinovirus (RRV), are unique in that they express vira

109 e terminal repeats of the genome of a rhesus rhadinovirus (RRV), strain 17577.

110 DNA replication (oriLyt) for rhesus macaque rhadinovirus (RRV), the rhesus macaque homolog of human

111 ma-associated herpesvirus and rhesus macaque rhadinovirus (RRV), two closely related gammaherpesvirus

112 losely related primate virus, rhesus macaque rhadinovirus (RRV), which infects and induces disease in

113 -free infection by the related rhesus monkey rhadinovirus (RRV), which is relatively even more depend

114 V2, the pig-tailed macaque homolog of rhesus rhadinovirus (RRV).

115 SHV), and the closely related rhesus macaque rhadinovirus (RRV).

116 (MneRV-2)," with close similarity to rhesus rhadinovirus (RRV).

117 isolates derived from these species (rhesus rhadinovirus [RRV] and pig-tailed rhadinovirus [PRV]).

118 ses (rhesus lymphocryptovirus [rLCV], rhesus rhadinovirus [RRV], and Japanese macaque rhadinovirus [J

119 The rhesus rhadinovirus strain 17577 (RRV strain 17577) genome is e

120 functional protein encoded by members of the rhadinovirus subfamily of gammaherpesviruses, including

121 Among the gamma-2-herpesvirus (rhadinovirus) subfamily, this includes expression of the

122 ough KSHV and HVS are related members of the rhadinovirus subgroup of gamma herpesviruses, K1 and STP

123 K1 of KSHV, other members of the gamma-2 or rhadinovirus subgroup of herpesviruses.

124 of potential cross-reactivity to the rhesus rhadinovirus sVCA homologue could be demonstrated using

125 human herpesvirus TKs, KSHV TKs and related rhadinovirus TKs are constitutively tyrosine phosphoryla

126 survived, a property shared with the related rhadinovirus TKs of rhesus monkey rhadinovirus and herpe

127 evidence of an evolutionary transition from rhadinoviruses to lymphocryptoviruses.

128 pesvirus, provisionally named "M. nemestrina rhadinovirus type 2 (MneRV-2)," with close similarity to

129 tified in African green monkeys, Chlorocebus rhadinovirus types 1 and 2 (ChRV-1 and ChRV-2) reveals t

130 Further comparisons with KSHV and other RV1 rhadinoviruses will provide important avenues for dissec