ライフサイエンスコーパス: rheumatoid factor

1 psoriasis, antinuclear antibodies [ANA], and rheumatoid factor).

2 ucleoproteins (snRNPs), dsDNA, and self IgG (rheumatoid factor).

3 -cyclic citrullinated peptide (anti-CCP) and rheumatoid factor.

4 ng peak levels of antihistone, anti-DNA, and rheumatoid factor.

5 n of disease, level of formal education, and rheumatoid factor.

6 of symptom onset) who were seropositive for rheumatoid factor.

7 ow-affinity, polyreactive human (h)IgM/kappa rheumatoid factor.

8 Both DQ8.CD8(-/-) and DQ8 mice produced rheumatoid factor.

9 t nodules in the absence of detectable serum rheumatoid factor.

10 y stronger in patients who were positive for rheumatoid factor.

11 ted to patients whose sera were negative for rheumatoid factor.

12 ic, nuclear, and platelet autoantibodies and rheumatoid factor.

13 anti-chromatin, anti-dsDNA, anti-ssDNA, and rheumatoid factor.

14 23- B cell secreting immunoglobulin M, kappa rheumatoid factor.

15 mentation rate, C-reactive protein level, or rheumatoid factor.

16 VH gene that partially encodes an anti-IgG2a rheumatoid factor.

17 reased levels of endogenous anti-DNA Abs and rheumatoid factor.

18 red for the development of antichromatin and rheumatoid factor.

19 hyroperoxidase antibody, and 37 positive for rheumatoid factor.

20 inatus correlated with the presence of ACPAs/rheumatoid factor.

21 nts, anti-citrullinated protein antibody and rheumatoid factor.

22 trullinated peptide (anti-CCP) antibody, and rheumatoid factor.

23 evels of anti-dsDNA, anti-chromatin, and IgM rheumatoid factors.

24 ing to the pathogenic potential of 6-19 IgG3 rheumatoid factors.

25 elevated ESR (87 mm/hr), CRP (156 mg/L), and rheumatoid factor (184 IU/mL).

26 s), though none had systemic symptoms: 18.8% rheumatoid factor; 6.25% SS-A/SS-B; 31.3% early Sjogren

27 Anti-CCP2 had greater specificity than rheumatoid factor (96% vs. 86%), with similar sensitivit

28 ma cells producing an IgG3 cryoglobulin with rheumatoid factor activity against IgG2a of allotype a p

29 profile, level of alanine aminotransferase, rheumatoid factor activity, C4 fraction of complement, a

30 -69 encoded antibodies that have anti-IgG or rheumatoid factor activity.

31 te in women and more frequent positivity for rheumatoid factor among both men and women.

32 t circulating autoantibodies, including both rheumatoid factor and anti-citrullinated protein antibod

33 he ability of baseline serum measurements of rheumatoid factor and anti-cyclic citrullinated peptide

34 Although, reduced titers of rheumatoid factor and anti-cyclic citrullinated peptide

35 r nail psoriasis and in the usual absence of rheumatoid factor and anti-cyclic citrullinated peptide.

36 x studies examined outcome predictions using rheumatoid factor and antikeratin/anticyclic citrullinat

37 variate analysis were AKIN stage 3, positive rheumatoid factor and biclonal gammopathy at diagnosis.

38 mmation, and autoantibodies (particularly to rheumatoid factor and citrullinated peptide).

39 Rheumatoid factor and complement C4 levels were normal i

40 ve B cells producing antinuclear antibody or rheumatoid factor and exhibit the skewed Ig V gene reper

41 Rheumatoid factor and SE were also predictors to a lesse

42 e, disease duration, and baseline values for rheumatoid factor and the tender and swollen joint count

43 ce gavaged with E. lenta produce preclinical rheumatoid factor and, when induced for arthritis, devel

44 imited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein anti

45 aracteristics of IgG binding by gE-gI and by rheumatoid factors and bacterial Fc receptors such as St

46 high-sensitivity C-reactive protein (hsCRP), rheumatoid factor, and anti-citrullinated protein antibo

47 a combination of the CSQ, joint examination, rheumatoid factor, and anti-cyclic citrullinated peptide

48 ogic studies for antinuclear antibody (ANA), rheumatoid factor, and antibodies to extractable nuclear

49 A combination of age, sex, smoking, rheumatoid factor, and anticyclic citrullinated peptide

50 Serum IgE, rheumatoid factor, and antinuclear antibodies and skin s

51 High mean platelet volume, positive rheumatoid factor, and antinuclear antibodies were all s

52 edimentation rate, C-reactive protein level, rheumatoid factor, and antinuclear antibody levels were

53 on rate, hemoglobin, white count, platelets, rheumatoid factor, and antinuclear factor.

54 une features such as hypergammaglobulinemia, rheumatoid factor, and circulating immune complexes are

55 d for optimal production of IgG autoAbs, IgM rheumatoid factor, and other clinical parameters of dise

56 es to citrullinated protein antigens (ACPA), rheumatoid factor, and symptoms, such as inflammatory jo

57 sociated with serum anti-SSA/SSB positivity, rheumatoid factor, and the ocular component of SS, but n

58 with childhood-onset RA, which is defined as rheumatoid factor- and/or anti-citrullinated protein ant

59 including anti-DNA, anti-Smith antigen, and rheumatoid factor; and glomerulonephritis.

60 No association with rheumatoid factor, anti-cyclic citrullinated peptide, or

61 YYAA mice, like SKG mice, develop rheumatoid factor antibodies, but fail to develop autoim

62 otein, erythrocyte sedimentation rate (ESR), rheumatoid factor, anticitrullinated protein antibodies

63 idence of interaction between the effects of rheumatoid factor, antinuclear antibodies, positive skin

64 C-reactive protein, rheumatoid factor, antinuclear antibody, cytoplasmic ant

65 looked for a broad range of autoantibodies (rheumatoid factor, antinuclear antibody, smooth muscle a

66 The frequency of rheumatoid factor at 3 years postinfection was 29.5% and

67 us nodules or finger clubbing, low titers of rheumatoid factor at onset of lung disease, lymphocytosi

68 mphoid malignancy in the formation of public rheumatoid factor autoantibodies responsible for mixed c

69 more severe lupus, as judged by anti-DNA and rheumatoid factor autoantibodies, total serum Ig isotype

70 D88, had markedly reduced chromatin, Sm, and rheumatoid factor autoantibody titers.

71 pendent autoreactive EF response elicited in rheumatoid-factor B cells by DNA-containing immune compl

72 n non-B cells, we transferred anti-self-IgG (rheumatoid factor) B cells and their physiologic target

73 i-IgG2a rheumatoid factor, but not 46-42 IgA rheumatoid factor bearing the same IgA allotype, develop

74 ents have clonal expansions of hypermutated, rheumatoid factor-bearing marginal zone-like IgM(+)CD27(

75 iated with SSc-ILD were anti-CCP antibody or rheumatoid factor (beta coefficient, 2.652 [95% CI 1.472

76 rence from other serum proteins, prealbumin, rheumatoid factor, bilirubin, estrogen, or C-reactive pr

77 tive binding to ssDNA, dsDNA, and IgG (i.e., rheumatoid factor), but not to histones or Sm.

78 with hybridoma secreting 6-19 IgA anti-IgG2a rheumatoid factor, but not 46-42 IgA rheumatoid factor b

79 ndent Ags, including 23 anti-HIV mAbs and 51 rheumatoid factors, but differed from that of 43 Abs to

80 Mice with FIA possess rheumatoid factor, circulating immune complexes, and ant

81 tions such as the presence of high levels of rheumatoid factors, circulating immune complexes, anti-D

82 o arthritis-related self proteins, including rheumatoid factor, citrullinated peptide, and type II co

83 nti-cyclic citrullinated peptide antibodies, rheumatoid factor, complement levels, and cytokine level

84 rent, and the VH and V kappas encoding these rheumatoid factors contained a high frequency of somatic

85 o patients randomized to receive MTX who had rheumatoid factor data.

86 Monoclonal 6-19 IgG3 anti-IgG2a rheumatoid factor derived from lupus-prone MRL-Fas(lpr)

87 phenotype studies, anti-nuclear antibody and rheumatoid factor determinations, marrow cytogenetics, a

88 l IgG, IgG anti-chromatin, anti-DNA, and IgM rheumatoid factor directed against IgG1 and against IgG2

89 stations in terms of increased production of rheumatoid factors due to TLR ligation on B cells.

90 rted cells, we show that these predominantly rheumatoid factor-encoding V(H)1-69/J(H)4 and V(kappa)3-

91 of severe human RA, including production of rheumatoid factor, enhanced T cell production, and monoc

92 iopathic arthritis (positive or negative for rheumatoid factor), extended oligoarticular juvenile idi

93 The presence of IgG rheumatoid factor (IgG-RF) preceded the development of a

94 The presence of IgM rheumatoid factor (IgM-RF), IgG-RF, IgA-RF, and IgG anti

95 o histones (H1-H5) and chromatin and for IgM rheumatoid factors (IgM-RFs).

96 Low levels of RF (rheumatoid factor), IL-12, and IL-17 were sensitive and

97 Small IgG rheumatoid factor immune complexes may provide the trigg

98 ied the presence of these autoantibodies and rheumatoid factor in blood donors who later developed rh

99 electively binds IgG molecules, an important rheumatoid factor in RA.

100 It is characteristic that the rheumatoid factor in serum is absent.

101 y (accumulation of anti-dsDNA antibodies and rheumatoid factor in serum, deposits of IgG and IgM in k

102 tions support a model for the origin of some rheumatoid factors, in which they represent anti-idiotyp

103 gion of mouse IgA and suggests that 6-19 IgA rheumatoid factor-induced GN could serve as an experimen

104 The rheumatoid factor is characteristically absent in the se

105 citrullinated peptide antibodies and/or >/=2 rheumatoid factor isotypes (a profile that is 96% specif

106 ambda(s) 29.5), leukocytosis (lambda(s) 25), rheumatoid factor (lambda(s) 11.0), anemia (lambda(s) 1.

107 lammation with local production of ACPAs and rheumatoid factors, leading to development of the 'mucos

108 otein level, erythrocyte sedimentation rate, rheumatoid factor level, tender joint count in 68 joints

109 IgG rheumatoid factor levels were significantly lower in the

110 rs with sequelae showed significantly higher rheumatoid factor levels.

111 ctive B cells in BALB/c AM14 transgenic (Tg) rheumatoid factor mice are not subject to central or per

112 The monoclonal rheumatoid factors (mRF) that bear the WA cross-idiotype

113 ing hyper IgM (n = 9), hyper IgG (n = 8), or rheumatoid factor (n = 55) did not cross-react with the

114 rheumatoid factor positive and 42 (40%) were rheumatoid factor negative.

115 Seven rheumatoid factor-negative JRA patients with polyarticul

116 n southern Europe (1360 [56.7%] of 2400) and rheumatoid factor-negative polyarthritis was more freque

117 In 358 children with oligoarthritis and rheumatoid factor-negative polyarthritis, erythrocyte se

118 ligoarthritis, rheumatoid factor-positive or rheumatoid factor-negative polyarthritis, or systemic JI

119 of juvenile idiopathic arthritis (JIA), IgM rheumatoid factor-negative polyarticular JIA and oligoar

120 the most common subtypes (oligoarticular and rheumatoid factor-negative polyarticular JIA), and 13,05

121 with persistent oligoarticular JIA, 45 with rheumatoid factor-negative polyarticular JIA, and 20 wit

122 g); the donor was the patient's HLA-matched, rheumatoid factor-negative sister.

123 ssion analysis determined that psoriasis and rheumatoid factor negativity were the most important fea

124 otein level, erythrocyte sedimentation rate, rheumatoid factor, nodular disease, modified Health Asse

125 t the Health Assessment Questionnaire score, rheumatoid factor, nodules, and swollen joint counts wer

126 Blood chemistry tests revealed a rheumatoid factor of 8.5 IU/mL (normal range, 0-13.9 IU/

127 marker for serodiagnosis of acute infection, rheumatoid factor often causes false-positive reactions.

128 urface of T cells, except in the presence of rheumatoid factor or activated monocytes.

129 rheumatoid arthritis (RA) include those with rheumatoid factor or anti-citrullinated protein antibody

130 CFA was also associated with the presence of rheumatoid factor or antinuclear antibodies, but not wit

131 /lpr mice; however, they did not develop IgG rheumatoid factors or anti-dsDNA, and lacked histologic

132 duction of antibodies to autoantigens (e.g., rheumatoid factor) or exogenous antigens, or it may repr

133 re disease progression, including a positive rheumatoid factor, or anti-cyclic citrullinated peptide

134 IgG deposition, levels of anti-dsDNA Ab and rheumatoid factor, or spleen weights between the two gro

135 ti-citrullinated protein antibodies (ACPAs), rheumatoid factors, or other autoantibodies.

136 Nevertheless, B cells representative of this rheumatoid factor population proliferate vigorously in r

137 Sixty-four (60%) RA cases were rheumatoid factor positive and 42 (40%) were rheumatoid

138 Children, especially girls, with rheumatoid factor positive polyarticular juvenile idiopa

139 -reactive protein level 42 mg/liter, and 65% rheumatoid factor positive).

140 Sixty percent of the patients with RA were rheumatoid factor positive.

141 All patients were rheumatoid factor positive.

142 69% of whom were female and 66% of whom were rheumatoid factor positive.

143 time of initiation of HCQ treatment (31-43% rheumatoid factor positive; no previous disease-modifyin

144 E) alleles were significantly more common in rheumatoid factor-positive (RF+) patients fulfilling the

145 ticular course JIA (extended oligoarthritis, rheumatoid factor-positive or rheumatoid factor-negative

146 iduals, Toxoplasma IgG-negative individuals, rheumatoid factor-positive persons, and persons determin

147 onset) and (2) JIA, except for the systemic, rheumatoid factor-positive polyarthritis, and enthesitis

148 of peripheral blood CD34+,CD45+ HPCs from 63 rheumatoid factor-positive RA patients and 48 controls m

149 n and 1.7% for men, and the lifetime risk of rheumatoid factor-positive RA was 2.4% for women and 1.1

150 Adolescent girls with polyarticular rheumatoid factor-positive subtype appear to be most vul

151 other self-report items, was associated with rheumatoid factor positivity (P = 0.047) and higher dise

152 proved significance when modeling DRB1*04 or rheumatoid factor positivity as covariates.

153 It was shown that rheumatoid factor positivity does not exclude a diagnosi

154 positive predictive value (PPV) (80.0%), and rheumatoid factor positivity the lowest (44.6%).

155 adjustment for CVD risk factors, joint pain, rheumatoid factor positivity, and inflammatory markers (

156 te models, the mean ESR, mean grip strength, rheumatoid factor positivity, and tender joint count wer

157 as no significant association with male sex, rheumatoid factor positivity, or erosive disease.

158 ge, sex, body mass index (BMI), smoking, and rheumatoid factor positivity.

159 er adjusting for age, sex, BMI, smoking, and rheumatoid factor positivity.

160 rmalities including antinuclear antibody and rheumatoid factor positivity.

161 ful in establishing the diagnosis of RA, but rheumatoid factor potentially provides the most useful p

162 We have previously shown that rheumatoid factors produced by Fas-deficient autoimmune-

163 that iNKT cells suppress IgG anti-DNA Ab and rheumatoid factor production and reduce IL-10-secreting

164 ain whether the combination of anti-CCP2 and rheumatoid factor provides additional benefit over anti-

165 indings of others that while the spontaneous rheumatoid factor response of lpr/lpr mice was oligoclon

166 ion pathways at early and late stages of the rheumatoid factor response.

167 B6-derived B cells produced more rheumatoid factor (RF) against their own IgG2b(b), while

168 Rheumatoid factor (RF) and anti-CCP were measured in ser

169 Rheumatoid factor (RF) and anti-citrullinated protein an

170 Rheumatoid factor (RF) and anti-cyclic citrullinated pep

171 Rheumatoid factor (RF) and autoantibodies against cyclic

172 Blood was obtained and analyzed for rheumatoid factor (RF) and CRP concentration.

173 Cigarette smoking is known to increase rheumatoid factor (RF) and nodule formation in patients

174 Serum rheumatoid factor (RF) and other heterophilic antibodies

175 linical surrogates to substitute for missing rheumatoid factor (RF) and radiologic erosion data was a

176 igins, we traced the evolution of pathogenic rheumatoid factor (RF) autoantibodies in four HCV-cryova

177 prone MRL-lpr/lpr (MRL-lpr) background, AM14 rheumatoid factor (RF) B cells are activated, differenti

178 Rheumatoid factor (RF) B cells function as highly effici

179 AM14 rheumatoid factor (RF) B cells in the MRL/lpr mice are a

180 High-affinity pathologic rheumatoid factor (RF) B cells occur in autoimmune disea

181 Rheumatoid factor (RF) B cells proliferate during second

182 The proliferative response of autoreactive rheumatoid factor (RF) B cells to mammalian chromatin-co

183 ortant insights on RA and on the function of rheumatoid factor (RF) become apparent.

184 an diseases, autoreactive B cells expressing rheumatoid factor (RF) binding activity are prominent.

185 -cyclic citrullinated peptide (anti-CCP) and rheumatoid factor (RF) has been established.

186 In this study, we show in rheumatoid factor (RF) Ig-transgenic autoimmune-prone mi

187 .6 years prior to diagnosis) were tested for rheumatoid factor (RF) isotypes, anti-cyclic citrullinat

188 ept significantly reduced immunoglobulin and rheumatoid factor (RF) levels, but not anti-citrullinate

189 Here, using AM14 site-directed transgenic rheumatoid factor (RF) mice, we report that B cells can

190 k was higher among patients with RA who were rheumatoid factor (RF) positive (HR 2.59, 95% CI 1.95-3.

191 l as for the subgroups who were and were not rheumatoid factor (RF) positive at baseline.

192 s with early inflammatory arthritis who were rheumatoid factor (RF) positive, but were predictive in

193 Sixty-three percent were rheumatoid factor (RF) positive.

194 e swollen joints (8 versus 7), more frequent rheumatoid factor (RF) positivity (93% versus 84%), high

195 population studies have suggested that both rheumatoid factor (RF) production and rheumatoid arthrit

196 Rheumatoid factor (RF) production in rheumatoid arthriti

197 Rheumatoid factor (RF) production was found to be associ

198 Although rheumatoid factor (RF) seropositivity is a risk factor f

199 study was to define the structural basis for rheumatoid factor (RF) specificity and for the expressio

200 In separate analyses, we corrected for rheumatoid factor (RF) status and/or the presence of the

201 The rheumatoid factor (RF) status, C-reactive protein levels

202 Urinalysis and rheumatoid factor (RF) tests were conducted to evaluate

203 viral titers of WB and Pl, percentage of CP, rheumatoid factor (RF) titer, and serum alanine transami

204 osoma parasites, heterophile antibodies, and rheumatoid factor (RF) titers.

205 We have analyzed B cell tolerance in a rheumatoid factor (RF) transgenic mouse model.

206 Patients with RA who were seropositive for rheumatoid factor (RF) were more likely to have moderate

207 Baseline age and rheumatoid factor (RF) were significantly different betw

208 eline specimens, we measured serum anti-CCP, rheumatoid factor (RF), and antinuclear antibody in a de

209 ous combinations of ICD code 714, a positive rheumatoid factor (RF), and prescription for a disease-m

210 to cyclic citrullinated peptide (anti-CCP), rheumatoid factor (RF), and the 620W PTPN22 allele.

211 Autoantibodies, including rheumatoid factor (RF), are an important characteristic

212 Rheumatoid factor (RF)-expressing B lymphocytes in norma

213 persistent oligoarticular and polyarticular rheumatoid factor (RF)-negative juvenile idiopathic arth

214 Rheumatoid factor (RF)-negative patients with exposure t

215 an biomarkers for the classification of both rheumatoid factor (RF)-positive and negative RA patients

216 he onset of rheumatoid arthritis (RA) in 182 rheumatoid factor (RF)-positive European American patien

217 ), particularly in those with polyarticular, rheumatoid factor (RF)-positive JRA.

218 Patients ages 2-18 years with rheumatoid factor (RF)-positive or RF-negative polyarthr

219 ll-cause and CVD mortality were increased in rheumatoid factor (RF)-positive patients and in this sub

220 when restricted to more seriously affected (rheumatoid factor (RF)-positive) patients.

221 the severity of rheumatoid arthritis than is rheumatoid factor (RF).

222 IgG) make a class of autoantibodies known as rheumatoid factor (RF).

223 c citrullinated peptide (CCP) antibodies and rheumatoid factor (RF).

224 zyme-linked immunosorbent assay [ELISA]) and rheumatoid factor (RF; by nephelometry or ELISA for IgA,

225 ism, and approximately 16% were positive for rheumatoid factor (RF; including isotypes) and/or anti-c

226 Rheumatoid factors (RF) and the disease-specific anti-ci

227 Rheumatoid factors (RF) associated with arthritic joint

228 Rheumatoid factors (RF) recognize conformational determi

229 Half of 30 human polyclonal IgM rheumatoid factors (RF) showed positive ELISA reactions

230 tibodies including IgA-, IgM-, and IgG-class rheumatoid factors (RF), and of antibodies to cyclic cit

231 tended oligoarthritis, polyarthritis (either rheumatoid factor [RF] positive or RF negative), or syst

232 stemic inflammation and RA disease severity (rheumatoid factor [RF] seropositivity, erythrocyte sedim

233 B cells with specificity for self-IgG2a (the rheumatoid factor [RF] specificity) to understand how no

234 isit for any of 5 RA-related autoantibodies (rheumatoid factor [RF], anti-cyclic citrullinated peptid

235 , 42 with persistent oligoarthritis, 45 with rheumatoid factor [RF]-negative polyarthritis, and 21 wi

236 Rheumatoid factors (RFs) are a dominant class of autoant

237 mapped the specificity of 28 monoclonal IgM rheumatoid factors (RFs) produced by heterohybridomas de

238 and serum levels of BLyS, IgM, IgA, and IgG rheumatoid factors (RFs), anti-cyclic citrullinated pept

239 Rheumatoid factors (RFs)-IgM and -IgA were measured by E

240 resence of erosions at baseline, presence of rheumatoid factor, rheumatoid factor titer, and HLA-DRB1

241 In contrast to the functional, rheumatoid factor-secreting CD27(+)CD21(high) subset, th

242 and does not efficiently differentiate into rheumatoid factor-secreting plasmablasts, suggesting tha

243 Within the RA group, rheumatoid factor seropositivity and higher cumulative p

244 isability scores, C-reactive protein levels, rheumatoid factor seropositivity, and a lack of current

245 deformed joint counts, subcutaneous nodules, rheumatoid factor seropositivity, and erythrocyte sedime

246 ed CIA predominantly in females and produced rheumatoid factors, similar to the features of human RA.

247 AB29 transgenic mice expressing a hIgM/kappa rheumatoid factor specific for human IgG, with no detect

248 n between the presence of erosive disease or rheumatoid factor status and the dose of rheumatoid epit

249 odified Larsen score, demographic variables, rheumatoid factor status, and carriage of HLA-DRB1 share

250 age but were largely similar across sex and rheumatoid factor status, as were the HRs for VTE across

251 for age, sex, body mass index, smoking, and rheumatoid factor status.

252 as were the HRs for VTE across age, sex, and rheumatoid factor status.

253 ic and nephritogenic activities of 6-19 IgG3 rheumatoid factor, terminal sialylation attenuated the n

254 ormal level, <10 mg/L), were normal, and the rheumatoid factor test result was negative.

255 toantibodies to histones, DNA, or IgG (i.e., rheumatoid factors), the Vkappa regions, with those from

256 edimentation rate [ESR], C-reactive protein, rheumatoid factor, the HLA-DRB1 shared epitope, and cumu

257 pondyloarthropathies are not associated with rheumatoid factor, they show a strong association with H

258 at baseline, presence of rheumatoid factor, rheumatoid factor titer, and HLA-DRB1*04 alleles, partic

259 Rheumatoid factor titer, HLA-DRB1 polymorphisms, age, an

260 unt of fibrosis and the percentage of CP and rheumatoid factor titer, yet neither of the latter param

261 antibody titers among SLE patients and with rheumatoid factor titers among seropositive RA patients.

262 -small nuclear ribonucleoprotein (snRNP) and rheumatoid factor titers, but failed to promote the deve

263 lysozyme BCR transgenic strain and the AM14 rheumatoid factor transgenic strain.

264 elapse was associated with high pretreatment rheumatoid factor values, and FCR was inversely associat

265 d two distinct more galactosylated 6-19 IgG3 rheumatoid factor variants.

266 or associations between RA and RF+ (positive rheumatoid factor) vs. mental health (depression, anxiet

267 Rheumatoid factor was not detected.

268 s, antidrug antibodies, body mass index, and rheumatoid factor were independently inversely associate

269 f rheumatoid arthritis positive for ACPA and rheumatoid factor with inflammatory joint pain were recr