ライフサイエンスコーパス: rhythmicity

1 EC neuronal hyperactivity and impaired theta rhythmicity.

2 positional information can be used to create rhythmicity.

3 eurons that control network excitability and rhythmicity.

4 gulation of endosymbiosis and exhibit a diel rhythmicity.

5 ges in firing rate or firing synchronization/rhythmicity.

6 Nor are the changes in sensitivity due to CS rhythmicity.

7 in CKI protein levels sufficient for normal rhythmicity.

8 however, the basal ganglia develop amplified rhythmicity.

9 nt insights into the mechanisms of circadian rhythmicity.

10 and cognition are also affected by circadian rhythmicity.

11 d corresponding restoration of circadian HPA rhythmicity.

12 e and SCN firing, and disrupting behavioural rhythmicity.

13 NAi)) of qsm, NKCC, or Shaw led to robust LL rhythmicity.

14 subsequently induce an increased respiratory rhythmicity.

15 d striatum that promotes synchronization and rhythmicity.

16 ts of human health and disease display daily rhythmicity.

17 es in MDD to restore and stabilize circadian rhythmicity.

18 heating increased thalamocortical slow-wave rhythmicity.

19 erase mice following UCMS to assess cellular rhythmicity.

20 2+) channels play a critical role in cardiac rhythmicity.

21 ptic plasticity and cerebellar Purkinje cell rhythmicity.

22 that drive moment-to-moment changes in theta rhythmicity.

23 etabolic consequences of disturbed circadian rhythmicity.

24 overy and/or strengthening of synchrony, and rhythmicity.

25 teady-state mRNA level, despite Noc's robust rhythmicity.

26 clock than for entrainment of organism-level rhythmicity.

27 on the other hand, is required for circadian rhythmicity.

28 oop, which was thought to generate sustained rhythmicity.

29 nels control neuronal and cardiac electrical rhythmicity.

30 cic segments leads to a weakening of scratch rhythmicity.

31 required for robust and sustained circadian rhythmicity.

32 ich is functionally important in maintaining rhythmicity.

33 ompared with cells exhibiting high-amplitude rhythmicity.

34 yocytes but also drastically compromised the rhythmicity.

35 were applied to each time series to describe rhythmicity.

36 ittle effect at night, and decreased circuit rhythmicity.

37 ng Tip60 HAT expression drastically weakened rhythmicity.

38 chrony of the SCN and stability of circadian rhythmicity.

39 ck and sleep influences on overall metabolic rhythmicity.

40 s of the expressed genes exhibited circadian rhythmicity.

41 imal locomotor activity and body temperature rhythmicity.

42 f-day-specific effects on firing and circuit rhythmicity.

43 H31R, in DN1ps mainly regulates free-running rhythmicity.

44 ich are essential for constant darkness (DD) rhythmicity.

45 xonal target areas fire with a low degree of rhythmicity.

46 tive feedback loops that generate endogenous rhythmicities.

47 MSG-treated hamsters that retained circadian rhythmicity after DPS treatment, quantitative parameters

48 immunopositive Teevra cells show the highest rhythmicity among MS neurons and fire with short burst d

49 ling, lncRNAs, and CRFH and how these impact rhythmicity, amplitude, period, and phase of circadian c

50 p, which manifests into changes in molecular rhythmicity and abnormal circadian behavioral output.

51 ortant roles in modulating hepatic circadian rhythmicity and aging.

52 the activity of HE neurons had also lost its rhythmicity and appeared tonic, and production of peptid

53 revealed that type of work, changes in daily rhythmicity and changes in sleep drive predict spatial m

54 ce of the sleep-wake distribution to diurnal rhythmicity and circadian processes.

55 k, and they collectively shape the circadian rhythmicity and composition of the fecal microbiota in m

56 othesis that body mass and T2DM affect daily rhythmicity and concentrations of circulating metabolite

57 otype in squirrel monkeys: loss of circadian rhythmicity and emergence of approximately 4-h sleep/wak

58 o the progressive dysregulation of circadian rhythmicity and entrainment seen in HD mice.

59 tide-gated (HCN) channels control electrical rhythmicity and excitability in the heart and brain, but

60 Theta rhythmicity and feedforward input from grid cell network

61 separate contribution of sleep and circadian rhythmicity and found that the sleep-wake cycle coordina

62 abolished both velocity modulation of theta rhythmicity and grid cell firing patterns.

63 Human performance is modulated by circadian rhythmicity and homeostatic sleep pressure.

64 interventions aimed at stabilizing circadian rhythmicity and improving sleep in dementia, namely time

65 ling of firing periodicity relative to theta rhythmicity and it partitions the theta cycle into segme

66 adian (E) neurons that are a major source of rhythmicity and locomotor activity.

67 erefore, visible light can modulate cellular rhythmicity and metabolism through unexpectedly photosen

68 ective of this study was to characterize the rhythmicity and phase coherence of core clock genes and

69 pal place cells exhibiting significant theta rhythmicity and phase precession were observed, which ma

70 an oscillator, which plays a pivotal role in rhythmicity and phase resetting of the circadian clock.

71 s, and >100 transcripts exhibited consistent rhythmicity and phase synchrony across regions.

72 Artificial light delays circadian rhythmicity and preferred sleep timing and compromises s

73 ughout the brain destabilize corticothalamic rhythmicity and produce this phenotype.

74 rior basal forebrain, displayed strong theta rhythmicity and responded with precise single spikes aft

75 These data establish the impact of circadian rhythmicity and sex on waking cognition and have implica

76 he effects of this polymorphism on circadian rhythmicity and sleep homeostasis by introducing the pol

77 el incorporating effects of light, circadian rhythmicity and sleep homeostasis to provide a quantitat

78 in general, is the balance between circadian rhythmicity and sleep need, rather than sleep homoeostas

79 yer 3 neurons showed only weak spiking theta rhythmicity and sparse head-direction selectivity.

80 Because our approach exploits the rhythmicity and sparse structure of neural activity, fea

81 n show prestimulus activity, licking-related rhythmicity and taste responses.

82 ponsive transcriptional repressor, providing rhythmicity and temperature responsiveness to growth thr

83 e parasubiculum might shape entorhinal theta rhythmicity and the (dorsoventral) integration of inform

84 ion of the thalamocortical slow-wave pattern rhythmicity and the appearance of fast LFP spikes, with

85 but the requirement of peripheral clocks for rhythmicity and their effects on physiology are not well

86 euronal Ca(2+) current, strongly influencing rhythmicity and triggering neurotransmitter release thro

87 ay of TRN-VB synaptic circuits that generate rhythmicity and TRN cell-intrinsic mechanisms that contr

88 Gut microbes exhibit diurnal rhythmicity, and disruptions in this rhythmicity potenti

89 sults in reduced GluA4 expression, disrupted rhythmicity, and increased pyramidal neuron excitability

90 rrelatedness of sleep homeostasis, circadian rhythmicity, and metabolism.

91 processing, sensory gating, thalamocortical rhythmicity, and slow-wave sleep.

92 behavior, endocrine function, and circadian rhythmicity are all regulated by SIRT1.

93 mary, disruptions in metabolic and circadian rhythmicity are associated with increased fetal size, wi

94 on these observations we interpret circadian rhythmicity as an emerging property of the circadian net

95 identify the disruption of normal circadian rhythmicity as an independent risk factor for hepatocell

96 of spike-wave morphology, frequency, diurnal rhythmicity, associated immobility, and sensitivity to t

97 her this discrepancy reflects differences in rhythmicity at a cellular level, we performed whole-cell

98 regulation plays a major role in determining rhythmicity at the mRNA level.

99 The sleep-wake cycle and circadian rhythmicity both contribute to brain function, but wheth

100 ty genes exhibited ultradian transcriptional rhythmicity, both in vivo and in vitro, including 5 gene

101 scillators differed in frequency, power, and rhythmicity, but both required GABAA and AMPA receptors.

102 ns showed only weak directionality and theta-rhythmicity, but were significantly modulated by angular

103 plication abolished both overt and molecular rhythmicities by repressing frequency (frq) gene transcr

104 Taken together, CLOCK modulates metabolic rhythmicity by acting as a rhythmic acetyl-transferase f

105 pression of BcFRQ1, or by suppression of its rhythmicity by constant light, abrogates circadian regul

106 Core clock genes were analyzed for rhythmicity by cosinor fit.

107 ous darkness, showing that the regulation of rhythmicity by RITMO1 is not directly dependent on light

108 y by conventional statistics and for 24-hour rhythmicity by the cosinor method.

109 an variability and that distinct patterns of rhythmicity can be recognized depending on the signal de

110 underlying phenomena as diverse as circadian rhythmicity, cell cycle control, stress and damage respo

111 challenge induces a loss of serum metabolite rhythmicity compared with liver, indicating a circadian

112 phila clock neurons that regulate behavioral rhythmicity contribute to temperature synchronization at

113 but another possibility is that an intrinsic rhythmicity contributes to low frequencies in behavior.

114 REBH in the liver exhibits typical circadian rhythmicity controlled by the core clock oscillator BMAL

115 Circadian rhythmicity demonstrated phase alignment within function

116 tion of homeostatic glucocorticoid circadian rhythmicity due to chronic stress exposure is correlated

117 n = 109), with 78 of these maintaining their rhythmicity during 24 h of wakefulness, most with reduce

118 t of genes that adopted increased or de novo rhythmicity during aging, enriched for stress-response f

119 nd into mechanisms essential for respiratory rhythmicity during normal breathing.

120 creates and maintains cellular and systemic rhythmicity essential to homeostasis.

121 Rhythmicity facilitates the coordination of neuronal act

122 t virtually all oscillating metabolites lost rhythmicity following treatment.

123 d into different groups based on strength of rhythmicity for a subset of triglycerides and phosphatid

124 Loss of circadian rhythmicity fundamentally affects the neuroendocrine, im

125 As a consequence of this mitotic rhythmicity, hairs grow faster in the morning than in th

126 To date, the molecular mechanism behind this rhythmicity has remained elusive.

127 Although core regulatory components of clock rhythmicity have been defined, insight into the mechanis

128 Underlying mechanisms for the shift in rhythmicity have not been identified experimentally, but

129 to how the relationship between dopamine and rhythmicity impacts motor function.

130 DF may act on DN1ps to regulate free-running rhythmicity in a hierarchical manner.

131 altered sympatho-vagal regulation of cardiac rhythmicity in adults characterized by a chronotropic in

132 s the circadian period and impairs circadian rhythmicity in animals.

133 Patients with bipolar disorder show altered rhythmicity in body temperature and melatonin rhythms, h

134 his mechanism could contribute to electrical rhythmicity in cells.

135 he oscillator structure for accurately timed rhythmicity in changing environmental conditions.

136 toward a "morning" chronotype and a loss of rhythmicity in circulating hormones.

137 The model results reveal the rhythmicity in deadenylation as the strongest contributo

138 Rhythmicity in expression was found in approximately 10%

139 The lack of theta rhythmicity in FS interneurons suggests that different m

140 tion was not associated with overt circadian rhythmicity in GHT output, indicating modulation at the

141 ivity, as evidenced by the lack of circadian rhythmicity in GR-deficient B cell counts normally assoc

142 ), consistent with the depletion and loss of rhythmicity in hepatic glycogen levels.

143 d into the trough of insulin action and lack rhythmicity in insulin action and activity patterns.

144 als the presence and coordination of diurnal rhythmicity in intracellular organelles.

145 tion on hepatic transcriptome and metabolome rhythmicity in male C57BL/6 mice orally gavaged with 2,3

146 le in the regulation of body homeostasis and rhythmicity in mammals.

147 ulation in the bee brain, disrupts circadian rhythmicity in many individual bees, shifts the timing o

148 metabolic challenge, rather than drive basal rhythmicity in metabolic activity.

149 f GABAergic input to the PVH reduces diurnal rhythmicity in metabolism and causes obesity.

150 GABAergic neurotransmission mediates diurnal rhythmicity in metabolism and is implicated in diet-indu

151 r hypothalamic (PVH) neurons reduces diurnal rhythmicity in metabolism, causes obesity and diminishes

152 evels, both show obesity and reduced diurnal rhythmicity in metabolism.

153 c steatosis and inflammation display diurnal rhythmicity in mice developing steatohepatitis upon feed

154 leotide-modulated (HCN) ion channels control rhythmicity in neurons and cardiomyocytes.

155 Interestingly, a set of transcripts gained rhythmicity in older individuals, which may represent a

156 nd jet lag, is associated with disruption of rhythmicity in physiology and endocrinology.

157 nylation as the strongest contributor to the rhythmicity in poly(A) tail length and the rhythmicity i

158 er, most of these transcripts do not exhibit rhythmicity in poly(A) tail length or steady-state mRNA

159 ver, hundreds of genes were found to exhibit rhythmicity in poly(A) tail length, and the poly(A) rhyt

160 Here we report clear evidence of 7-9 Hz rhythmicity in raw intra-hippocampus EEG traces during r

161 ents at the preBotC imparts the network with rhythmicity in reduced states of arousal, although the n

162 We report daily rhythmicity in responsiveness to PDF in critical pacemak

163 cell-autonomous and network-level circadian rhythmicity in SCN never previously exposed to CRY.

164 We also identify age-onset rhythmicity in several putative primary piRNA transcript

165 re tetrameric proteins that evoke electrical rhythmicity in specialized neurons and cardiomyocytes.

166 e rhythmicity in poly(A) tail length and the rhythmicity in the abundance of the mRNA subpopulation w

167 had a beneficial effect on restoring normal rhythmicity in the diabetic cornea.

168 with insulin partially restored the altered rhythmicity in the diabetic cornea.

169 a core molecular clock component, abolished rhythmicity in the fecal microbiota composition in both

170 al encounters were associated with increased rhythmicity in the high theta range (7-10 Hz) that was p

171 Rhythmicity in the intravascular reactivity of adherent

172 nded to a fearful stimulus by enhancement of rhythmicity in the low theta range (3-7 Hz).

173 HD cell characteristics while sparing theta rhythmicity in these regions.

174 Measuring circadian behavioral and SCN rhythmicity in these temporally chimeric male mice thus

175 ndance and identified 13 taxa with disrupted rhythmicity in type 2 diabetes (T2D).

176 ociated sympathetic innervation in governing rhythmicity in vascular inflammation in both arteries an

177 because of a perceived absence of ultradian rhythmicity in vitro and a lack of known molecular ultra

178 nging phenomena such as ultradian (2-3 hour) rhythmicity in whole blood samples of the common vole (M

179 being involved in several aspects of cardiac rhythmicity, including cardiac conduction, pace making a

180 Circadian rhythmicity is a defining feature of mammalian metabolis

181 Moreover, when circadian rhythmicity is absent or severely disrupted, it is not k

182 Such rhythmicity is also observed in cultured neurons from th

183 Circadian rhythmicity is an approximately 24-h cell-autonomous per

184 In the basal ganglia, focused rhythmicity is an important feature of network activity

185 Disruption of circadian rhythmicity is associated with obesity and related disor

186 of membrane currents regulating pathological rhythmicity is both degenerate and age-dependent.

187 Circadian rhythmicity is created endogenously by genetically encod

188 different from those of layer 2, where theta rhythmicity is prominent and spatially modulated cells o

189 hy (EEG) studies have demonstrated that this rhythmicity is reflected by the phase of ongoing brain o

190 Importantly, this rhythmicity is required by the processes underlying the

191 p between physiological factors and cortical rhythmicity is required.

192 When rhythmicity is rescued in the Bmal1-knockout mice by exp

193 lled conditionality; namely, that endogenous rhythmicity is robustly expressed under some environment

194 An important step in generating rhythmicity is the translocation of clock components int

195 king, has motor parallels with speech in its rhythmicity, its developmental trajectory, and the coord

196 or genetically induced deregulation of brain rhythmicity led to disrupted circadian ILC3 oscillations

197 euron firing rates exhibit significant 10-Hz rhythmicity locked to song syllables, peaking prior to s

198 In contrast, contributions to circadian rhythmicity made by a handful of post-translational mech

199 effects of these polymorphisms on circadian rhythmicity may affect sleep duration and body weight re

200 With increasing acuity of illness, circadian rhythmicity may be lost entirely.

201 ggest that cellular disruption of clock gene rhythmicity may occur by mechanisms shared with inflamma

202 The rapid shift in rhythmicity might be more common across migratory songbi

203 ersistent disruptions in sleep and circadian rhythmicity, mimicking attributes of stress-related cond

204 The altered rhythmicity observed in RITMO1 overexpression lines in c

205 across languages, with a preferred range of rhythmicity of 2- 8 Hz.

206 lic acetylation of AceCS1 contributes to the rhythmicity of acetyl-CoA levels both in vivo and in cul

207 ns of interneurons that set the strength and rhythmicity of behaviors such as locomotion.

208 Rhythmicity of biological functions is fundamental for o

209 w-wave sleep (SWS), as well as the circadian rhythmicity of body temperature and locomotor activity.

210 at Ano1 is required to maintain coordination/rhythmicity of Ca(2+) transients.

211 Twenty-four-hour rhythmicity of circulating metabolites: effect of body m

212 x at an interstimulus interval mimicking the rhythmicity of descending late indirect (I) waves in cor

213 In late mouse pregnancy, rhythmicity of energy metabolism-related genes in the mu

214 display unique features (i.e., strong theta rhythmicity of firing, prominent head-direction selectiv

215 ABA-A receptor gamma2 subunit, and dampening rhythmicity of GABAergic input to the PVH reduces diurna

216 Circadian rhythmicity of gene expression has been observed in anim

217 tic XBP1 predominantly regulates the 12-hour rhythmicity of gene transcription in the mouse liver and

218 rum and muscle metabolites and regulates the rhythmicity of genes controlling amino acid transport, w

219 (h) GH gene (hGH1) locus to investigate the rhythmicity of hGH synthesis and secretion and to show t

220 S-DBB glutamatergic neurons did increase the rhythmicity of hippocampal theta oscillations, whereas s

221 Furthermore, STRA6 is necessary for diurnal rhythmicity of insulin action and JAK/STAT signaling in

222 and demonstrates that disturbing the natural rhythmicity of insulin action will disrupt the rhythmic

223 However, the mechanisms driving rhythmicity of ischemic vascular events are unknown.

224 tical excitability, and that the 1- to 10-Hz rhythmicity of LC discharge appeared to increase the pow

225 back control, and suggest that the intrinsic rhythmicity of motor cortical networks reflects an inter

226 The circadian rhythmicity of oxygen consumption rate (Vo2) was disrupt

227 nism for the observed inversion of the daily rhythmicity of pain sensation under neuropathic pain con

228 The diurnal rhythmicity of phagocytosis is almost lost, indicated by

229 short-term TRF in overweight men affects the rhythmicity of serum and muscle metabolites and regulate

230 In muscle, TRF induces rhythmicity of several amino acid transporter genes and

231 TCDD diminished the rhythmicity of several core clock regulators (e.g. Arntl

232 ld properties correlate with theta-frequency rhythmicity of spiking and membrane-potential resonance;

233 ied parasubicular neurons shows strong theta rhythmicity of spiking, a large fraction of head-directi

234 marrow was associated with loss of circadian rhythmicity of stem/progenitor cell release into the cir

235 ng has the opposite effect; it increases the rhythmicity of thalamocortical slow oscillation.

236 nsulin-dependent diabetes altered the normal rhythmicity of the cornea, and insulin administration ha

237 anisms use endogenous clocks to adapt to the rhythmicity of the environment and to synchronize social

238 be under strong selection, influenced by the rhythmicity of the environment.

239 type Ca(2+) channels which contribute to the rhythmicity of the heart and brain.

240 ion provide a fast feedback that can enhance rhythmicity of the intracellular circadian clock.

241 Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fe

242 Here, we examined diurnal rhythmicity of the RBP4/STRA6 signaling axis and investi

243 neural oscillations beyond the timescale and rhythmicity of the stimulus.

244 tive, these latter circuits will entrain the rhythmicity of the thoracic circuitry.

245 ey are rhythmically active, will entrain the rhythmicity of the thoracic circuitry.

246 The rhythmicity of their firing decreases from septal to tem

247 e systems and the consequences of distorting rhythmicity of these systems.

248 isms that underlie the initiation and robust rhythmicity of UP states are unknown.

249 imed electrical drives collaborate to impose rhythmicity on Drosophila clock neurons.

250 Circadian rhythmicity, one of the key adaptations of life forms on

251 1,591 in BA47) that exhibited age-dependent rhythmicity or alterations in rhythmicity patterns with

252 inct types dependent on whether they display rhythmicity or not during locomotion.

253 tified metabolites, 7 (22%) exhibited cosine rhythmicity over at least one 24 h period; 5 exhibiting

254 with machine learning to identify microbial rhythmicity patterns that predict Type 2 Diabetes incide

255 age-dependent rhythmicity or alterations in rhythmicity patterns with aging.

256 ough circadian activation is critical to ccg rhythmicity, posttranscriptional regulation plays a majo

257 diurnal rhythmicity, and disruptions in this rhythmicity potentially impact host health.

258 und that epochs of highly synchronized theta rhythmicity preferentially occurred during behavioral ta

259 current magnitudes, and reduced SCN circuit rhythmicity recorded by multi-electrode arrays.

260 ein, we demonstrate that dietary content and rhythmicity regulate the diurnally shifting SI epithelia

261 ffects the molecular regulators of circadian rhythmicity remains to be established.

262 thm, yet the physiological relevance of this rhythmicity remains unclear.

263 acetylation of AceCS1 is cyclic and that its rhythmicity requires a functional circadian clock and th

264 ive polyadenylation (APA), display circadian rhythmicity resulting from oscillation in the genes invo

265 distinct, but together they control de novo rhythmicity, setting ensemble period and phase with circ

266 Moreover, theta rhythmicity showed different pattern of coherence betwee

267 by a distinct default pattern of infra-slow rhythmicity.SIGNIFICANCE STATEMENT Information processin

268 ge set of clinical data showing that diurnal rhythmicity (sleep, temperature, mood and hormone secret

269 mismatch between sleep timing and circadian rhythmicity ('social jet-lag').

270 hifts, or weak or complete loss of circadian rhythmicity, suggesting alterations in circadian gene ex

271 ranscription-based oscillators for circadian rhythmicity, supported by the recent discovery of oxidat

272 ratory exchange ratio with a loss of diurnal rhythmicity that showed a gradual but incomplete recover

273 tical responses showed significant circadian rhythmicity, the phase of which varied across brain regi

274 for SCN function and whole animal circadian rhythmicity, the specific contributions of VIP cell outp

275 between the nuclear periphery and circadian rhythmicity, therefore bridging two global regulatory sy

276 ed role for MTA1 in maintenance of circadian rhythmicity through acting on the positive limb of the c

277 and PDF hierarchically regulate free-running rhythmicity through DN1ps.

278 We found the age-related transition from rhythmicity to arrhythmicity for each parameter occurs u

279 ents PDF function in regulating free-running rhythmicity using male flies.

280 of a single functional allele of dpCry2, and rhythmicity was abolished in the absence of dpCRY2.

281 ion of the KaiB and KaiC proteins, intrinsic rhythmicity was enhanced at cool temperatures that are e

282 Significant circadian rhythmicity was identified in five of six core clock gen

283 We demonstrate that although behavioural rhythmicity was maintained in diet-induced obesity (DIO)

284 Although variation due to circadian rhythmicity was not a significant source of variation in

285 ivity was markedly reduced and rest-activity rhythmicity was undetectable, neither of which was repli

286 ch subtle dynamic changes in the contractile rhythmicity were delicately illustrated.

287 signals, normal place cell firing and theta rhythmicity were found.

288 und that activity in the heart tubes and its rhythmicity were greatly diminished.

289 (ii) 58% of these genes lose transcriptional rhythmicity when the IDC is out-of-synchrony with host r

290 f-function mutants (Dh31(#51)) showed normal rhythmicity, whereas Dh31(#51);Pdf(01) double mutants ex

291 arly to Nipped-A RNAi knockdown and weakened rhythmicity, whereas reducing Tip60 HAT expression drast

292 ates that elicit different patterns of theta rhythmicity, which cause the same brain areas to communi

293 ibly by driving velocity modulation of theta rhythmicity, which may be used as a speed signal to gene

294 undance of Bacteroidetes exhibited circadian rhythmicity, which was more pronounced in female mice.

295 This modulation of theta rhythmicity, which was specific for social stimuli, appe

296 liana) rosettes displays a genuine circadian rhythmicity with a peak around midday.

297 tly rhythmic in old flies, while others lost rhythmicity with age, resulting in constitutive over- or

298 l composition and function exhibit circadian rhythmicity with fasting-feeding.

299 rm of NOC possesses high-amplitude circadian rhythmicity with peak expression level during the early

300 g of suprachiasmatic nucleus (SCN) circadian rhythmicity, would compromize the generation of ultradia