ライフサイエンスコーパス: ribonuclease

1 ion can regulate the activity of a bacterial ribonuclease.

2 iRNA precursors by the Translin-Trax (Tn-Tx) ribonuclease.

3 aled depletion of omega1 transcripts and the ribonuclease.

4 the first example of a self-limiting CRISPR ribonuclease.

5 ivates the effector, typically a promiscuous ribonuclease.

6 ript to attack by 5'-monophosphate-dependent ribonucleases.

7 transcripts had little in common between the ribonucleases.

8 monophosphate-assisted cleavage by these two ribonucleases.

9 tranded RNA substrates, a rare quality among ribonucleases.

10 ry transcripts by 5'-monophosphate-dependent ribonucleases.

11 ertoire of regulatory strategies employed by ribonucleases.

12 rovide evidences that the Arabidopsis S-like Ribonuclease 1 (RNS1) might be involved in the biogenesi

13 use of the Csy-type (CRISPR system yersinia) ribonuclease 4 (Csy4) and tRNA processing enzymes to sim

14 Angiogenin (ANG) and ribonuclease 4 (RNASE4), two members of the secreted and

15 We previously identified ribonuclease 7 (RNase 7) as a human antimicrobial peptid

16 Using ribonuclease A (RNase A) and saporin as two representati

17 for inhibition of the enzymatic activity of ribonuclease A (RNase A).

18 p-aminobenzamidine (pABA), bovine pancreatic ribonuclease A (RNaseA), and uridine-3'-phosphate (3'UMP

19 kinetics, as demonstrated by the binding of ribonuclease A (RNaseA, 13.7 kDa) with cytidine nucleoti

20 panning the N-terminal 20 residues of bovine ribonuclease A (S peptide).

21 ers of [PO(3)]((-)), can bind to the enzymes ribonuclease A and NAD kinase, raising the question of w

22 models of ribonuclease cleavage and for the ribonuclease A enzyme itself, based on our studies of th

23 atalysis of RNA 2'-O-transphosphorylation by ribonuclease A is proposed to involve electrostatic stab

24 tations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are k

25 Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic

26 n-6 with barium chloride, and the binding of ribonuclease A with cytidine 2'-monophosphate within rea

27 pon unfolding of model proteins lysozyme and ribonuclease A, in solutions containing varying cosolute

28 helix formation in the isolated C-peptide in ribonuclease A, there is growing evidence that a signifi

29 Model proteins were studied: ribonuclease A, trypsin inhibitor, and carbonic anhydras

30 reduced non-specific displacement by BSA and ribonuclease A.

31 g a protein corona structure consisting of a ribonuclease-A (RNase-A) on the particle surfaces.

32 d eosinophils can result in unwanted cell or ribonuclease activation, leading to poor cell viability

33 The retention of a conserved ribonuclease active site as well as traits normally asso

34 'lasso' because it binds RNA and stimulates ribonuclease activities associated with Rrp44 and Rrp6 w

35 The ribonuclease activities of these complexes require tight

36 d to date possess two enzymatically distinct ribonuclease activities that are required for optimal in

37 Cas13a (formerly C2c2) contains two separate ribonuclease activities that catalyze crRNA maturation a

38 data highlight a communicative link between ribonuclease activity and central metabolism that may ha

39 Conversely, loss of ANG stability and ribonuclease activity correlated with longer survival fo

40 ome is a well-conserved protein complex with ribonuclease activity implicated in RNA metabolism.

41 or the cA4 ligand, a canonical cA4-activated ribonuclease activity in the Csx1 domain and a potent cA

42 combinant RNase 7 mutant showed that RNase 7 ribonuclease activity is dispensable for the observed re

43 The ribonuclease activity of deadenylase enzymes is attribut

44 ntly to animal cells, it does not temper the ribonuclease activity of inositol-requiring enzyme 1 (IR

45 forms of IRE1b it was demonstrated that the ribonuclease activity of IRE1 was required for protectin

46 Here we detail methods for detection of the ribonuclease activity of MazFSa, including a continuous

47 oadenylate (cOA) compounds that activate the ribonuclease activity of Pfu Csx1.

48 Loss of BMI1 enhanced ribonuclease activity of polynucleotide phosphorylase an

49 Ribonuclease activity of topoisomerase I (Top1) causes D

50 The toxin exerts a unique ribonuclease activity that cleaves the single-stranded 3

51 tly exhibited heightened levels of cytosolic ribonuclease activity that corresponded to substantial d

52 sure a robust but time-limited cOA-activated ribonuclease activity that is finely tuned to cA4 levels

53 xhibits a "collateral effect" of promiscuous ribonuclease activity upon target recognition.

54 Loss of ANG stability and ribonuclease activity were found to correlate with early

55 elicase activity and its relationship to the ribonuclease activity were not clear.

56 toxin 28 (Ntox28) domain that only exhibits ribonuclease activity when bound to the cysteine biosynt

57 vented S-nitrosylation and inhibition of its ribonuclease activity, indicating that Cys931 is the pre

58 e S-nitrosylation of IRE1alpha inhibited its ribonuclease activity, S-nitrosylation of PERK activated

59 sure to heat, leaving Sll1130 to exhibit its ribonuclease activity.

60 t highly purified NOC possesses little or no ribonuclease activity.

61 helicase activity that is independent of its ribonuclease activity.

62 small spheres on the surface, which retained ribonuclease activity.

63 performance and strict structural demands of ribonuclease activity.

64 , resulting in a significant increase of its ribonuclease activity.

65 se RNA maturation component poly(A)-specific ribonuclease affect the maturation and stability of telo

66 We demonstrated that Zt6 is a functional ribonuclease and that phytotoxicity is dependent on both

67 hain ribosomal RNAs that remain uncleaved by ribonucleases and assemble onto messenger RNA.

68 of this family maintain independent roles as ribonucleases and modulators of innate immunity.

69 RNA processing by ribonucleases and RNA modifying enzymes often involves s

70 Specialized ribonucleases and RNA-binding proteins govern the produc

71 ia the coordinated action of nuclear encoded ribonucleases and RNA-binding proteins.

72 ed actions of both PARN (a metazoan-specific ribonuclease) and RRP12 (a phylogenetically conserved 40

73 terize another RNase 1 homolog, bovine brain ribonuclease, and find pronounced similarities between t

74 The ribonuclease angiogenin is a component of the mammalian

75 The ribonuclease angiogenin is a component of the mammalian

76 mature tRNAs are cleaved by stress-activated ribonuclease angiogenin to generate 5'- and 3'-tRNA halv

77 related with expression of the tRNA-cleaving ribonuclease, angiogenin.

78 transcription and availability of the Dicer ribonuclease are the key determinants for primary siRNA

79 in vivo, and that the activities of the two ribonucleases are co-ordinated.

80 Ribonucleases are critically important in many cellular

81 Peptidyl-oligonucleotide ribonucleases are here chemically engineered to create a

82 otecting distal cleavage sites en masse from ribonuclease attack.

83 rd proteins myoglobin (m/z-value 16,950) and ribonuclease B (m/z-value 14,900) were measured with res

84 on of over 20 high-mannose glycan isomers in ribonuclease B and a diverse range of hybrid and complex

85 died using bovine fetuin, asialofetuin, IgG, ribonuclease B, and alpha-1 acid glycoprotein (AGP) by P

86 the well-characterized glycoproteins bovine ribonuclease B, human transferrin, bovine fetuin and hum

87 Here, we describe a probe and ribonuclease based strategy for bacterial rRNA removal.

88 th mRNAs, (e) regulatory proteins that alter ribonuclease binding affinities, (f) the presence or abs

89 ous ribonucleases or induction of endogenous ribonucleases by trypsin reagent proteases to RNA degrad

90 the programmable single-effector RNA-guided ribonuclease Cas13.

91 in the PARN gene (encoding poly(A)-specific ribonuclease) cause telomere diseases including familial

92 s a mechanism we have proposed for models of ribonuclease cleavage and for the ribonuclease A enzyme

93 m contrasts with earlier, generally accepted ribonuclease cleavage mechanisms where the proton donor

94 ar) 11, a divergent member of the eosinophil ribonuclease cluster, and the only known RNase A ribonuc

95 The RNA exosome is an essential ribonuclease complex required for processing and/or degr

96 The exosome is a conserved multi-subunit ribonuclease complex that functions in 3' end processing

97 strip incorporating an internal control for ribonuclease contamination, should facilitate SARS-CoV-2

98 a-adenylate (cA6) signalling pathway and the ribonuclease Csm6, rather than through DNA cleavage by t

99 clic tetra-adenylate (cA(4)), activating the ribonuclease Csx1, and showed that subsequent RNA cleava

100 llosterically activates the CRISPR ancillary ribonucleases Csx1/Csm6, which degrade RNA non-specifica

101 unusual fusion between cA4-activated CRISPR ribonuclease (Csx1) and a cA4-degrading ring nuclease (C

102 ding proteins HuR and PARN [Poly(A) specific ribonuclease deadenylase].

103 Here we show using RNA-seq analyses of ribonuclease-deficient strains in vivo and a 5'-sensor m

104 d on multivariate analysis, BSP5 and seminal ribonuclease defined the HF phenotype, while spermadhesi

105 RNA sequences by mass spectrometry involves ribonuclease digestion followed by LC-MS/MS analysis and

106 , creating a better substrate for subsequent ribonuclease digestion.

107 n, IRE1 activates its cytoplasmic kinase and ribonuclease domains to transduce the signal.

108 y the processing of longer precursors by the ribonucleases Drosha and Dicer.

109 In the presence of H-type ribonucleases, DSB repair proceeds through a complementa

110 (PNPase), ATP-dependent RNA helicase (RhlE), ribonuclease E (RNase E) and ribonuclease J (RNase J) as

111 cleolytic miRNA maturation, catalyzed by the ribonuclease EXO domain.

112 nuclease cluster, and the only known RNase A ribonuclease expressed specifically in response to Th2 c

113 The poly(A)-specific ribonuclease family deadenylase PNLDC1 is implicated in

114 into individual pre-tRNAs by one of several ribonucleases followed by 5' end maturation by ribonucle

115 plex without catalytic turnover for EMSA and ribonuclease footprinting analyses.

116 ouble-strand break repair machinery and as a ribonuclease for the regulation of mitochondrial transla

117 icutes have a fundamentally different set of ribonucleases for mRNA degradation and whether sRNAs can

118 emonstrate that Drosha and related RNase III ribonucleases from all three domains of life also elicit

119 effector C2c2 and demonstrate its RNA-guided ribonuclease function.

120 These ribonucleases function with the assistance of ancillary

121 nsing, nucleotide binding, dimerization, and ribonuclease functions highlights the evolutionary adapt

122 RNA digestions catalyzed by many ribonucleases generate RNA fragments that contain a 2',3

123 Since the ribonuclease H (RH) domain contains an occult cleavage s

124 e nucleic acid duplex in the vicinity of the ribonuclease H (RNase H) active site.

125 se (IN) and reverse transcriptase-associated ribonuclease H (RNase H) are both selective targets for

126 eolytic attack by HIV-1 protease cleaves the ribonuclease H (RNase H) domain of a single subunit to y

127 Two types of Ribonuclease H (RNase H) excise ribonucleotides when the

128 ng trajectories of ancestral proteins of the ribonuclease H (RNase H) family using ancestral sequence

129 idated reverse transcriptase (RT) associated ribonuclease H (RNase H) for human immunodeficiency viru

130 (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains an unvalidated antivira

131 Reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encode

132 (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains the only virally encode

133 To remove hybrids, all organisms use ribonuclease H (RNase H) to specifically degrade the RNA

134 INSTIs) that also displayed activity against ribonuclease H (RNase H).

135 associated DNA polymerase, and RT-associated ribonuclease H (RNase H).

136 mains and the acquisition of an Archaea-like ribonuclease H (RNH) domain.

137 all reduction in activity of T. thermophilus ribonuclease H compared to its mesophilic E. coli homolo

138 folding, dimerization and subunit-selective ribonuclease H domain (RH) proteolysis.

139 y essential aspartate to Mg(2+) or Ca(2+) in ribonuclease H from two organisms were computed using um

140 Loss-of-function mutations in ribonuclease H, senataxin, and topoisomerase I that reso

141 Ribonuclease H-like (RNHL) superfamily, also called the

142 strains, and between wild type and different ribonuclease H-mutant genotypes.

143 Encoding ribonuclease H1 (RNase H1) degrades RNA hybridized to DN

144 RNASEH1, encoding ribonuclease H1 (RNase H1), is an endonuclease that is p

145 gher RNA binding affinity but do not recruit ribonuclease H1 (RNase H1).

146 w the diverse thermostabilities of bacterial ribonuclease H1 (RNH) proteins evolved.

147 NA fiber analysis, we demonstrate that human ribonuclease H1 (RNH1) plays an important role in replic

148 Ribonuclease H1 ameliorates replication fork instability

149 These findings implicate ribonuclease H1 and RNA in the physical segregation of m

150 In cells with a pathological variant of ribonuclease H1 associated with mitochondrial disease, R

151 Ribonuclease H1 is essential for mitochondrial DNA repli

152 at can be disfavored in vitro and in vivo by ribonuclease H1 overexpression, resulting in VIM down-re

153 und that RNA-DNA recombination is blocked by ribonucleases H1 and H2.

154 enes encoding the genome surveillance enzyme ribonuclease H2 (RNase H2) cause Aicardi-Goutieres syndr

155 lleles of the genes encoding subunits of the ribonuclease H2 (RNase H2) complex, known for its role i

156 Ribonuclease H2 (RNase H2) is a nucleic acid repair enzy

157 Ribonuclease H2 plays an essential role for genome stabi

158 ed mice with epithelial-specific deletion of ribonuclease H2 subunit B (H2b(DeltaIEC)) and mice that

159 In analyses of mice with disruption of the ribonuclease H2 subunit B gene and colorectal tumors fro

160 cimens from 467 patients, measured levels of ribonuclease H2 subunit B, and associated these with pat

161 H2 is a holoenzyme, composed of 3 subunits (ribonuclease H2 subunits A, B, and C), that cleaves RNA:

162 These findings suggest that pancreatic ribonuclease has, in parallel, evolved a new role for di

163 In particular, ribonuclease HI (RNase H), an 18 kD globular protein tha

164 ups, (13)C(gamma/delta), in Escherichia coli ribonuclease HI (RNase H).

165 tion formed between Escherichia coli SSB and ribonuclease HI (RNase HI), an enzyme that hydrolyzes RN

166 e such mechanism is hydrolysis of R-loops by ribonuclease HI (RNase HI).

167 sis for reduced activity of the thermophilic ribonuclease HI enzyme from Thermus thermophilus, compar

168 Ribonuclease III (RNase III) enzymes are a family of dou

169 Ribonuclease III (RNase III) is a conserved, gene-regula

170 Dicer is a ribonuclease III enzyme in biosynthesis of micro-RNAs (m

171 er, a caspase-sensitive, fertility-promoting ribonuclease III enzyme, and key micro-RNAs in the repro

172 void requirements for host factors including ribonuclease III for bacterial RNA-mediated adaptive imm

173 ding Fem-3-binding-factor 2, Argonaute 2 and Ribonuclease III, NucleicNet can accurately recover inte

174 existence of citrate-mediated inhibition of ribonucleases in all three domains of life.

175 known about the mechanism of action of other ribonucleases in this microorganism.

176 f trypsin reagent identified the presence of ribonucleases in trypsin derived from animal pancreas.

177 protect siRNAs from degradation by serum and ribonucleases in vitro and upon intratumoral injection i

178 Ribonuclease inactivating point mutations are found in a

179 Experiments with a ribonuclease-inactive recombinant RNase 7 mutant showed

180 kin-derived native RNase 7 and a recombinant ribonuclease-inactive RNase 7 mutant.

181 ome profiling in yeast and mice with various ribonucleases including I, A, S7 and T1, characterized t

182 esigned leucine-rich repeats (LRRs) from the ribonuclease inhibitor (RI) family that assemble into st

183 Ribonuclease inhibitor (RI) is a conserved protein of th

184 gel electrophoresis revealed the endogenous ribonuclease inhibitor as the primary cellular target.

185 entering cells, ANG encounters the cytosolic ribonuclease inhibitor protein, which binds with femtomo

186 22-residue fragment; barstar, a fully folded ribonuclease inhibitor; R17, a 13.3 kDa system possessin

187 collagen I hydrogel membrane with entrapped ribonuclease inhibitors (RI) to protect small molecule R

188 IRE1 is a dual protein kinase/ribonuclease involved in the splicing of bZIP60 mRNA, an

189 cMazF) is the archetype of a large family of ribonucleases involved in bacterial stress response.

190 The plant UPR transducers are the kinase and ribonuclease IRE1 and the transcription factors bZIP28 a

191 volving the bifunctional protein kinase (PK)/ribonuclease, IRE1, a RNA splicing enzyme, and another i

192 This secreted ribonuclease is crucial for Th2 polarization and granulo

193 Angiogenin (ANG), a secreted vertebrate ribonuclease, is known to promote cell proliferation, le

194 NA, mediated by HuR, KSRP and its associated ribonucleases, is required for proper myogenesis.

195 elicase (RhlE), ribonuclease E (RNase E) and ribonuclease J (RNase J) as major components.

196 cking the 5'-->3' exonucleolytic activity of ribonuclease J (RNase J).

197 Here we found that ribonuclease kappa (RNASEK) is essential for the infecti

198 tethered transcription factor bZIP28 and the ribonuclease-kinase IRE1 along with its splicing target,

199 Ribonuclease L (RNase L) is a metal-ion-independent endo

200 nded RNA (dsRNA), protein kinase R (PKR) and ribonuclease L (RNase L) reprogram translation in mammal

201 -5' linked oligoadenylate (2-5A) to activate ribonuclease L (RNase L), which cleaves RNA to inhibit v

202 cleavage sites, (g) control of intracellular ribonuclease levels, and (h) physical location within th

203 Here, we use our ribonuclease-mediated structure and RBP-binding site map

204 re intrinsically resistant to degradation by ribonucleases, might be pursued as an alternative to ant

205 Our results suggest that brain ribonuclease, not RNase A, is the true bovine homolog of

206 MBL domain with CPSF73, as well as to other ribonucleases of the MBL superfamily.

207 lls, necessitating a means to deactivate the ribonuclease once viral infection has been cleared.

208 ncentration or specific activity of cellular ribonucleases or by unmasking the mRNA-degrading activit

209 The contribution of exogenous ribonucleases or induction of endogenous ribonucleases b

210 with MRPP2 and MRPP3, form the mitochondrial ribonuclease P (mt-RNase P) complex that cleaves the 5'

211 The mitochondrial form of ribonuclease P (mt:RNase P) is responsible for 5'-end ma

212 Ribonuclease P (RNase P) is an endonuclease that catalyz

213 Ribonuclease P (RNase P) is an essential endonuclease th

214 Ribonuclease P (RNase P) is essential for the 5'-end mat

215 Ribonuclease P (RNase P) is one of the first ribozymes d

216 re like a pre-tRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, to d

217 0 is an essential component of mitochondrial Ribonuclease P (RNase P), an enzyme required for mitocho

218 A single enzyme, ribonuclease P (RNase P), processes the 5' ends of tRNA

219 probe functions of conserved nucleobases in ribonuclease P (RNase P).

220 ocessing of precursor transfer RNA (tRNA) by ribonuclease P as a model system.

221 mponents-such as the RNA moiety of bacterial ribonuclease P-can sometimes be replaced with a highly d

222 bonucleases followed by 5' end maturation by ribonuclease P.

223 uR with the decay factor KSRP as well as the ribonuclease PARN and the exosome.

224 Germline mutations in poly(A)ribonuclease (PARN) cause accumulation of extended human

225 However, the role of poly(A) specific ribonuclease (PARN) deadenylase in miRNA-dependent mRNA

226 ations in the gene encoding poly(A)-specific ribonuclease (PARN) in 3 families with individuals exhib

227 ns in the gene encoding the poly(A)-specific ribonuclease (PARN) in individuals with a severe form of

228 Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease that plays a

229 Poly(A)-specific ribonuclease (PARN) is known to trim hTR precursors by r

230 Poly(A)-specific ribonuclease (PARN) is required for posttranscriptional

231 Here, we show that poly(A)-specific ribonuclease (PARN) participates in steps leading to 18S

232 coding mutations in TERT or poly(A)-specific ribonuclease (PARN), another gene linked to telomerase f

233 Ribonucleases play essential roles in all aspects of RNA

234 uced level of expression of core degradosome ribonucleases provided evidence of important pleiotropic

235 biochemical function in the pancreatic-type ribonuclease (ptRNase) superfamily.

236 vity, which bares resemblance to that of the ribonuclease reductase responsible for cellular dNTP pro

237 assembly, and its interaction with the core ribonuclease RNase E boosts the ATP-dependent activity o

238 e regulatory small RNA GlmZ to the essential ribonuclease RNase E for inactivation.

239 d processing of many RNAs is mediated by the ribonuclease RNase J, a member of the widely occurring m

240 ting evidence suggests that human pancreatic ribonuclease (RNase 1) plays important roles in vivo, ra

241 e mitochondria, the nucleus harbors a second ribonuclease (RNase H2).

242 We hypothesized that AMPs belonging to the Ribonuclease (RNase) A Superfamily are present in perito

243 sequencing of mRNA fragments protected from ribonuclease (RNase) digestion by ribosomes.

244 ntly enhance the number of detected modified ribonuclease (RNase) digestion products by approximately

245 Compounds that efficiently inhibit the ribonuclease (RNase) H activity of the human immunodefic

246 an RNA/DNA hybrid substrate by B. halodurans ribonuclease (RNase) H1 using hybrid quantum-mechanics/m

247 Mutations that impair ribonuclease (RNase) H2 enzyme function are the most fre

248 Human ribonuclease (RNase) H2 is the principal enzyme able to

249 ficiently removed in an error-free manner by ribonuclease (RNase) H2.

250 Members of the ribonuclease (RNase) III family regulate gene expression

251 The kinase activity of PERK and ribonuclease (RNase) of IRE1alpha mediated the upregulat

252 Angiogenin (ANG) is a secreted ribonuclease (RNase) with cell-type- and context-specifi

253 Cas12g is an RNA-guided ribonuclease (RNase) with collateral RNase and single-st

254 and glycosylated forms of bovine pancreatic ribonuclease (RNase).

255 related molecules (keratin 25, trichohyalin, ribonuclease, RNase A family, 7) and inflammation-relate

256 rtiodactyl ruminants) the enzymes pancreatic ribonuclease (RNASE1) and lysozyme C (LYZ), originally i

257 Pancreatic ribonuclease (RNASE1) is a digestive enzyme that has bee

258 inds with high affinity to diverse secretory ribonucleases (RNases) and inhibits their enzymatic acti

259 Ribonucleases (RNases) can be crucial factors contributi

260 Ribonucleases (RNases) maintain the cellular RNA pool by

261 are catalyzed by the double-strand specific ribonucleases (RNases) Mini-RNase III and RNase M5, resp

262 ibed as precursors and require processing by Ribonucleases (RNases) to generate mature and functional

263 with both human eosinophil granule cationic ribonucleases (RNases), namely, eosinophil-derived neuro

264 Consequently, RNA degrading enzymes (ribonucleases; RNases) such as the endoribonuclease RNas

265 inally, we provide evidence that Arabidopsis ribonuclease RNS1 might be involved in the processing an

266 Artificial virus-like capsids decorated with ribonuclease S (RNase S) on their exterior were construc

267 Human calmodulin and bovine ribonuclease S (RNase S) were screened against the libra

268 in binding peptide and S peptide as the only ribonuclease S binding peptide in the library.

269 bes in different solvent environments and in ribonuclease S to understand the sensitivity of carbonyl

270 This study provides a guide for ribonuclease selection in ribosome profiling experiments

271 e report that human RNase 1 and bovine brain ribonuclease share high catalytic activity against doubl

272 oblot analyses in the presence or absence of ribonuclease showed that these five RBPs are assembled i

273 bers of the secreted and vertebrate-specific ribonuclease superfamily, play important roles in cancer

274 on temperature of the unfolding enthalpy of ribonuclease T1 and the solvation enthalpies of the nonp

275 Ribonuclease T1 was the only enzyme that preserved ribos

276 le of an ancient extracellular RNase, called Ribonuclease T2 (RNASET2), within the ovarian stromal mi

277 Ribonuclease T2 gene (RNASET2) expression and methylatio

278 olecule targeted degradation of RNA targets (ribonuclease-targeted chimeras, RIBOTACs) and direct cle

279 e by recruiting an endogenous nuclease, or a ribonuclease targeting chimera (RIBOTAC).

280 ategies, such as bleomycin A5 conjugates and ribonuclease targeting chimeras (RIBOTACs), that allow f

281 attern and functional diversity of mammalian ribonuclease than previously thought.

282 ed protein TTHB144 is a cA(4)-activated HEPN ribonuclease that also degrades its activator.

283 ocyte (MK)-specific knockdown of Dicer1, the ribonuclease that cleaves miRNA precursors into mature m

284 uclease RNase J, the only prokaryotic 5'->3' ribonuclease that is commonly present in bacteria, Archa

285 Angiogenin (ANG) is a human ribonuclease that is compromised in patients with amyotr

286 pitated with polynucleotide phosphorylase, a ribonuclease that is responsible for decay of mtRNA tran

287 Angiogenin (ANG) is a ribonuclease that promotes cellular adaptation under str

288 Angiogenin (ANG) is a stress-activated ribonuclease that promotes the survival of motor neurons

289 a heterocycle that recruits and activates a ribonuclease to pre-miR-21 to substoichiometrically effe

290 ribonucleotides which can be cleaved by the ribonuclease to specifically initiate DNA amplification

291 ural information from chemical probes and/or ribonucleases to restrain RNA secondary structure predic

292 In some cases, ribonuclease treatment completely degraded ribosome popu

293 Ribonuclease V1 footprinting shows that hADAR2-D protect

294 ctivate downstream effectors, including Csm6 ribonucleases, via their CARF domains.

295 e, we observed that Sll1130 is a heat-stable ribonuclease whose activity was inhibited by Ssl2245 at

296 to capture 5' monophosphorylated RNA ends in ribonuclease wild-type and mutant strains.

297 this work characterizes a divergent RNase A ribonuclease with a unique expression pattern and functi

298 cium lead to the activation of an endogenous ribonuclease, XendoU.

299 structure of YfcM is similar to that of the ribonuclease YbeY, even though they do not share sequenc

300 Here, we characterized a secreted ribonuclease (Zt6) with an unusual biphasic expression p