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1 hosphorylated 4E-binding protein 1, and p-S6 ribosomal protein.
2 protein (RNP) complexes containing rRNAs and ribosomal proteins.
3 tags for the recombinant production of human ribosomal proteins.
4 Hel2-dependent regulatory ubiquitylation of ribosomal proteins.
5 e limited to fewer "core" genes, such as the ribosomal proteins.
6 f multiple nuclear DNA-encoded mitochondrial ribosomal proteins.
7 ukaryotic translation initiation factors and ribosomal proteins.
8 ensity, which affected mostly mRNAs encoding ribosomal proteins.
9 gger site-specific ubiquitination on several ribosomal proteins.
10 karyotic ribosomes are composed of rRNAs and ribosomal proteins.
11 mal proteins competes with production of non-ribosomal proteins.
12 d down-regulation of genes encoding rRNA and ribosomal proteins.
13 ation-initiation and elongation factors, and ribosomal proteins.
14 , as well as a reduction in transcription of ribosomal proteins.
15 many mRNAs, although not with those encoding ribosomal proteins.
16 els and translation efficiencies for several ribosomal proteins.
17 anscripts with high initiation rates such as ribosomal proteins.
18 the LSU, as well as previously unidentified ribosomal proteins.
19 th a specific decrease in the translation of ribosomal proteins.
20 -dependent upregulation of mitochondrial 37S ribosomal protein 1/ATP-binding cassette subfamily C mem
22 Our structures further uncover how specific ribosomal proteins act as chaperones to correctly fold t
27 by TGF-beta1 were characterised by increased ribosomal proteins and dysregulated proteins involved in
29 f the mitoribosome reveals an assembly of 94-ribosomal proteins and four-rRNAs with an additional pro
30 in hippocampal neurons resulted in increased ribosomal proteins and initiation factors, but decreased
31 rocess that involves the ordered assembly of ribosomal proteins and numerous RNA structural rearrange
33 dules thus obtained reveals an enrichment of ribosomal proteins and pathways likely central to inheri
36 Selection pressure led to the loss of two ribosomal proteins and removal of essentially all eukary
38 environmental effects is challenging because ribosomal proteins and rRNA preclude most spectroscopic
40 ent of specific protein families such as the ribosomal proteins and the DEAD box helicases, we identi
41 e nuclear import of approximately 80 nascent ribosomal proteins and the elimination of excess amounts
42 ith significantly lower expression levels of ribosomal proteins and transcriptional and translational
45 bly chaperones recognize nascent unassembled ribosomal proteins and transport them together with kary
46 stic insights into the complex dynamics of a ribosomal protein, and it proposes a previously underapp
47 transcription, recovery of transcription of ribosomal proteins, and initiation of wound healing and
48 d iPSS in the polycistronic operons encoding ribosomal proteins, and the majority upstream and proxim
50 The long unstructured domains of unassembled ribosomal proteins are highly prone to misfolding and of
53 f pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the linchpins of ribosome biogene
55 -transcriptional rRNA modifications and some ribosomal proteins are underrepresented in the accumulat
57 mplex and heterogeneous process during which ribosomal proteins assemble on the nascent rRNA during t
60 oroplast protein chaperone machinery and 70S ribosomal proteins, but other parts of the proteostasis
61 ble for import can maintain the stability of ribosomal proteins by neutralizing unfavorable positive
62 control that involves the ubiquitination of ribosomal proteins by the E3 ubiquitin ligase Hel2/RQT1.
64 logical culture, nucleic acid amplification, ribosomal protein characterization, and genome sequencin
66 dia-specific and several repurposed existing ribosomal proteins compensate for the extensive rRNA red
67 osomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribos
69 onsistent with general translation shutdown, ribosomal proteins contacting the mRNA showed decreased
71 RNA molecules dominate the mass and why the ribosomal protein content is divided into 55-80 small, s
72 ing thioredoxin as a fusion protein, soluble ribosomal protein could be obtained directly from cell l
74 rsions of OVA model Ags displaying defective ribosomal protein-dependent and -independent Ag presenta
75 on and metabolism, as well as those encoding ribosomal proteins, DNA and histone-modifying enzymes an
76 d Mrt4 that prevent premature loading of the ribosomal protein eL24, the protein-folding machinery at
77 gulates nutrient-dependent downregulation of ribosomal protein encoding RNAs, leading to the redistri
78 ts to silence Phytoene desaturase (PDS) or a ribosomal protein-encoding gene, RPL10 (QM), in Nicotian
79 cation of CD4(+) T cell responses to defined ribosomal protein epitopes expands the range of antigeni
80 dings suggest that the monoubiquitination of ribosomal protein eS7A plays a crucial role in translati
81 rganisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit
83 translated proteins but also at the level of ribosomal protein expression, ribosome assembly, and rib
84 or margin were associated with expression of ribosomal proteins (false discovery rate <0.25; NES, 1.9
85 is report, we analyzed the eight-member uL18 ribosomal protein family in Arabidopsis uL18 proteins sh
86 How stable proteins that rely on defective ribosomal proteins for direct presentation are captured
88 ignature, which is associated with defective ribosomal protein function and linked to the erythroid l
91 ted by translational repression, while HiToP ribosomal protein genes are regulated posttranslationall
92 t of cells appears to decouple expression of ribosomal protein genes from the environmental stress re
93 tern of enrichment around the start codon of ribosomal protein genes in all stages but male gametocyt
94 eterozygous allelic variation in 1 of the 20 ribosomal protein genes of either the small or large rib
95 bundant class of intron-containing RNAs (the ribosomal protein genes) to Mer1-regulated transcripts.
96 ith wide nucleosome-deficient regions (e.g., ribosomal protein genes), known to harbor partially-unwr
97 dates identified in this search included two ribosomal protein genes, RPL35a and RPL23, and ferredoxi
98 pes can withstand genetic lesions of certain ribosomal protein genes, some of which are linked to div
99 p of human disorders most commonly caused by ribosomal protein haploinsufficiency or defects in ribos
100 eveals that the RNA-binding capacity of uL18 ribosomal proteins has been repurposed to create factors
102 In addition, as excessive heme could amplify ribosomal protein imbalance, prematurely lower GATA1, an
107 ng rRNA variants and rRNA modifications, and ribosomal proteins, including their stoichiometry, compo
108 er acetylation occupancy and lower levels of ribosomal proteins, including those involved in ribosome
109 ncing of Rps19, but not several other tested ribosomal proteins, indicating distinct cellular respons
112 od about the recombinant production of human ribosomal proteins involved the recovery of proteins fro
113 on that explains how integration of the last ribosomal proteins is coupled to release of the nuclear
114 f mRNAs encoding cytosolic and mitochondrial ribosomal proteins is substantially repressed by HRI dur
115 ed a transgene that expresses an eGFP-tagged ribosomal protein (L10a) under the control of the macrop
116 n in bacterial 23S rRNA is directly bound by ribosomal protein L11, and this complex is essential to
117 fiers of F508del-CFTR biogenesis, from which ribosomal protein L12 (RPL12/uL11) emerged as a molecula
120 echanism of inflammation control directed by ribosomal protein L13a and "GAIT" (Gamma Activated Inhib
121 een and a pull-down assay identified plastid ribosomal protein L15, uL15c (formerly RPL15), as intera
122 conventional organelles, colocalize with the ribosomal protein L22, and cluster the WNK signaling pat
126 d identifies a G70D mutation in the RplD 50S ribosomal protein L4 as significantly associated with in
127 d protein synthesis requires isoforms of the ribosomal protein L4 encoded by the cytokinin-inducible
129 ooperativity of the C-terminal domain of the ribosomal protein L9 in the pressure-temperature plane u
131 iptomic analyses show progressive changes in ribosomal protein levels and mitochondrial function as e
132 ities were also correlated with the cellular ribosomal protein levels, thereby suggesting that mRNA p
134 a C. neoformans ccr4Delta mutant, stabilized ribosomal protein mRNAs are retained in the translating
137 n genome, many nuclear-encoded mitochondrial ribosomal proteins (MRPs) are required for proper functi
138 ppressed the expression of the mitochondrial ribosomal protein MRPS10 and reduced 12S ribosomal RNA (
140 enin/MMP signaling and a YY1/lncRNA ESCCAL-1/ribosomal protein network are uncovered and validated as
144 y, coordinated translational upregulation of ribosomal proteins only occurred in the liver but not in
145 tants deficient in PSRP7, a plastid-specific ribosomal protein, OTP86, an RNA editing factor, and cpP
149 mes; to accomplish this task, ribosomes make ribosomal proteins, polymerases, enzymes, and signaling
150 ession of pre-ribosomal RNAs (pre-rRNAs) and ribosomal proteins, pre-rRNA processing, and subunit ass
151 LARP4 is a posttranscriptional regulator of ribosomal protein production in mammalian cells and sugg
152 cluding multiple aminoacyl tRNA synthetases, ribosomal proteins, protein chaperones, and the Clp syst
153 ocesses: RNA processing; gene transcription; ribosomal proteins; protein degradation; and metabolism
155 owth, cells must manage a massive economy of ribosomal proteins (r-proteins) and RNAs (rRNAs) to prod
157 s mediated by an interaction with a specific ribosomal protein, RACK1, and that an increase in cytopl
159 hly charged proteins, such as histone H1 and ribosomal proteins, requires a dimer of two transport re
160 duration of feast and the allocation of the ribosomal protein reserve to maximize the overall gain i
161 To visualize co-transcriptional assembly of ribosomal protein-RNA complexes in real time, we develop
165 wild-type cells and cells with mutations in ribosomal protein (Rp) genes in Drosophila melanogaster.
166 r in strains in which deletion of individual ribosomal protein (RP) genes leads to globally increased
168 most often due to heterozygous mutations in ribosomal protein (RP) genes that lead to defects in rib
169 ve results from a detailed analysis of human Ribosomal Protein (RP) levels in normal and cancer sampl
171 ls, TOR specifically promotes translation of ribosomal protein (RP) mRNAs when amino acids are availa
176 stence of eukaryotic ribosomes with distinct ribosomal protein (RP) stoichiometry and regulatory role
178 congenital disorders caused by mutations in ribosomal proteins (RP) or assembly factors and are char
179 gested that MYC drives the overexpression of ribosomal proteins (RP)L5 and RPL11, which bind and inhi
183 novo splice variants in RPL13, which encodes ribosomal protein RPL13 (also called eL13), in four unre
184 munoprecipitates with RNA polymerase I, with ribosomal proteins RPL26 and RPL24, and with components
185 Here, we show that a largely uncharacterized ribosomal protein, RPL26, is the principal target of UFM
190 folding and local autonomy of assembly with ribosomal proteins (rProteins), and that the rProtein an
191 omozygotes lacking any of the five different ribosomal proteins (RPs) can produce fully functional fi
192 ow cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotyp
193 ation in eukaryotes created paralog pairs of ribosomal proteins (RPs) that show high sequence similar
196 equences that follow genetic knockout of the ribosomal proteins RPS25 or RACK1 in a human cell line,
199 ould inhibit trans-translation by binding to Ribosomal protein S1 (RpsA) and competing with tmRNA, th
200 binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) and inhibits trans-translati
205 raction between the translation enhancer and ribosomal protein S1 to repress translation of manY mRNA
208 atterns of three putative dual-coding genes, ribosomal protein S12 (RPS12), the 5' editing domain of
212 that ectopic expression of the mitochondrial ribosomal protein S18-2 (MRPS18-2) led to immortalizatio
213 rt novel immunosuppressive properties of the ribosomal protein S19 (RPS19), which is upregulated in h
214 Here, we report that AtPRMT3 interacts with Ribosomal Protein S2 (RPS2), facilitating processing of
216 Specifically, human growth hormone 1, murine ribosomal protein S27, and murine ATP synthase H(+) tran
217 Differential expression of the RPS27L (40S ribosomal protein S27-like) gene, part of the p53/mammal
220 nduce an up-regulation of phosphorylated (p)-ribosomal protein S6 (rpS6) (namely, p-rpS6-S235/S236) a
221 hypochromic skin patches, we identified the ribosomal protein S6 (RPS6) p.R232H variant, present as
223 ted protein kinase (AMPK) alpha (Thr172) and ribosomal protein S6 (Ser235/Ser236) was performed using
228 IL-7 treatment increased levels of phospho-ribosomal protein S6 in HIV-specific CD8 T cells, sugges
229 e genes Nr4a1 and Irf8 and activation of the ribosomal protein S6 is also conserved across stimuli.
231 e, we show that multisite phosphorylation of ribosomal protein S6 kinase 1 (S6K1) alters target selec
234 of mammalian target of rapamycin complex 1, ribosomal protein S6 kinase 1, and eukaryotic translatio
235 ma model in which constitutive activation of ribosomal protein S6 kinase A1 drives tumor invasion.
239 age proinflammatory activation by catalyzing ribosomal protein S6 kinase beta-1 (S6K1) O-GlcNAcylatio
240 lular signal-regulated kinase) and S6K-RPS6 (ribosomal protein S6 kinase-ribosomal protein S6) axes.
241 educed constitutive activation of the mTORC1/ribosomal protein S6 pathway and downregulated constitut
242 es expressed higher levels of phosphorylated ribosomal protein S6 than paired fibroblasts from normal
243 1(Thr412) , 19%; p70 S6K1(Thr389) , 58%) and ribosomal protein S6(Ser235/236) (37%), greater rested-s
250 hyde-3 phosphate dehydrogenase (GAPDH), 40 S ribosomal protein S9 (RpS9) and ubiquitin-conjugating pr
252 umber of rRNA genes, and codon usage bias in ribosomal protein sequences were all higher in the ferti
253 global folds, including similarity to early ribosomal proteins, similar small molecule ligand bindin
255 tors of RAN translation and identified small ribosomal protein subunit 25 (RPS25), presenting a poten
256 his drug across glioma cell lines, revealing ribosomal protein subunit RPS11, 16, and 18 as putative
257 slation-related proteins such as 50S and 30S ribosomal protein subunit variants and elongation factor
258 ons in the expression of the large and small ribosomal protein subunits (RPL and RPS, respectively) i
259 ssion of specific isoforms of genes encoding ribosomal proteins, suggesting that alterations in prote
260 lision in vivo resulted in ubiquitination of ribosomal proteins, suggesting that collision is sensed
261 nsity at their C-terminus are overwhelmingly ribosomal proteins, suggesting the possibility that this
262 olecular dynamics simulations show that each ribosomal protein switches the 16S conformation and damp
266 ient mutants, NMD-susceptible transcripts of ribosomal proteins that are known for their role as nonc
267 protein complex comprises specific rRNAs and ribosomal proteins that are organized into functional do
269 probable only in the presence of additional ribosomal proteins that bind upstream and downstream of
270 osomes involves the hierarchical addition of ribosomal proteins that progressively stabilize the fold
271 tide and thioamide backbone substitutions in ribosomal proteins, the former likely conserved in all d
272 studies using human marrow erythroid cells, ribosomal protein transcripts and proteins increase, and
273 ells (CD71(+)Ter119(neg-lo)), heme increases ribosomal protein transcripts, suggesting that heme, in
275 ms reveal the importance of stalling-induced ribosomal protein ubiquitination by Hel2/ZNF598 for both
276 o-terminal amphipathic helix of SecA and the ribosomal protein uL23 form a composite binding site for
277 linking indicated that F399 in SecA contacts ribosomal protein uL29, and binding to nascent chains di
278 e functions of two NPET-associated proteins, ribosomal protein uL4 and assembly factor Nog1, in NPET
279 e suggest that altering the conformations of ribosomal protein uL6 and rRNA helix H69, which interact
281 th growth, including many encoding cytosolic ribosomal proteins, underwent distinct histone modificat
282 ere we report that ubiquitination of the 40S ribosomal protein uS10 by the E3 ubiquitin ligase Hel2 (
284 within the ribosomal S11 domain in the yeast ribosomal protein uS11 shows impaired growth and defecti
285 nking of aldehyde derivatives of RNAs to the ribosomal protein uS3 through its peptide 55-64 located
287 le molecule FRET to show how combinations of ribosomal proteins uS4, uS17 and bS20 in the 16S 5' doma
289 etween A-3 and the conserved beta-hairpin of ribosomal protein uS7 fails to diminish the contribution
291 that encode translation machinery, including ribosomal proteins, was upregulated during the T cell cl
294 avoidance of host transcripts encoding host ribosomal proteins, which are required by IAV for replic
295 avoidance of host transcripts encoding host ribosomal proteins, which are required by IAV for replic
296 oteins of a cell, comprise ribosomal RNA and ribosomal proteins, which coassemble hierarchically duri
297 n the phylogenies of both 16S rRNA genes and ribosomal proteins, which we propose to name (U)Petromon
298 y (LC-MS/MS) enable direct quantification of ribosomal proteins with high specificity, accuracy, and
299 ransferase center, and stable association of ribosomal proteins with rRNA surrounding the polypeptide
300 osomal ubiquitylation (RRub) on distinct 40S ribosomal proteins, yet the cellular role and fate of ub