ライフサイエンスコーパス: ring expansion

1 istically interesting products (e.g., double ring expansion).

2 igration, similar to that in a Dowd-Beckwith ring expansion.

3 I) species that does not catalyze productive ring expansion.

4 t with both radical rearrangement and cation ring expansion.

5 er isomers were prone to ring opening and/or ring expansion.

6 er, affect the overall barrier to reversible ring expansion.

7 to the ketone followed by rearrangement and ring expansion.

8 nation, followed by cycloreversion-initiated ring expansion.

9 This reaction is competitive with the ring expansion.

10 g, Two-Directional Synthesis, and Successive Ring Expansion.

11 trogen ylide formation followed by azetidine ring expansion.

12 cyclopropyl gold(I) carbenes, followed by a ring expansion.

13 ng groups, and provides a method for n-->n+4 ring expansion.

14 o the formal 6-endo products via homoallylic ring expansion.

15 (I)-templated helical knot precursor through ring expansion.

16 ylation, monoatomic phosphide insertion, and ring-expansion.

17 alladation, Pd oxidation, and chemoselective ring expansion 1,2-Csp(3)/Pd(IV) dyotropic rearrangement

18 rearrange into cyclohexyne (with DeltaE for ring expansion=-15.1 kcal mol(-1) ).

19 sis providing both the 5,5,6- and, through a ring expansion, 5,5,7-tricyclic ring systems present in

20 rearrange into cyclopentyne (with DeltaE for ring expansion=-6.2 kcal mol(-1) ).

21 These pathways result in five-membered ring expansion-a critical mechanism crucial to PAH mass

22 on yields cyclopropylidenecyclobutane, while ring-expansion affords bicyclo[3.2.0]hept-1(5)-ene.

23 ted tethered alkylidyne tungsten complex for ring expansion alkyne metathesis polymerization (REAMP)

24 ynthesis include an oxiranium mediated ether ring expansion, an oxa-Michael/retro-oxa-Michael cascade

25 y whereas actin reorganizes through cortical ring expansion and clearance from the poles.

26 opane-stabilized carbocation, which triggers ring expansion and concomitant 1,2-metalate rearrangemen

27 As such, the known mechanisms for ring expansion and contraction determine the classes of

28 unusual reactions, including ring couplings, ring expansion and contraction, and fusion of substrates

29 e, is proposed to form and partition between ring expansion and direct fragmentation to alkene; event

30 cules are involved in the catalyst-regulated ring expansion and eventual cyclization, forming authent

31 egioselective, and convergent method for the ring expansion and rearrangement of 1-sulfonyl-1,2,3-tri

32 to the natural product through a sequential ring expansion and reduction strategy.

33 Ring expansion and ring fragmentation products were synt

34 lowed by an intermolecular reaction during a ring-expansion and a ring-extrusion reaction followed by

35 (6) core bridging, (7) ring contraction, (8) ring expansion, and (9) C-H and C-C bond activation.

36 ric epoxidation of benzylidenecyclopropanes, ring expansion, and Baeyer-Villiger oxidation.

37 ding Sequential Cycloaddition/Fragmentation, Ring Expansions, and Miscellaneous.

38 cyclooctane fragment relies on an oxidative ring-expansion, and complete stereochemical relay in the

39 A "ring expansion-annulation strategy" for the synthesis of

40 ductant to access aryl nitrenes, which after ring expansion, are trapped by amine nucleophiles to giv

41 d with our experimental measurements of swim ring expansion as a function of time, demonstrating good

42 The sulfones were found to undergo ring expansion at a much higher rate compared to the thi

43 e skeletal editing of organic frameworks via ring expansion at the level of one or more aliphatic (me

44 plausible mechanism of tetrahydropyrimidine ring expansion based on DFT calculation at B3LYP/6-31+G(

45 A novel ring expansion based on the readily available 2-azido-2-

46 They do not undergo ring expansion but form basic nitrenes that protonate to

47 s (F and Cl) raise the activation barrier to ring expansion by approximately 5 kcal/mol.

48 nate carbodiimide, and the scarcely observed ring expansion by insertion of a chloro(imino)phosphine

49 contraction within the carbene prevails over ring-expansion by a factor of 6.7:1.

50 that the core bromonium-induced cyclization/ring-expansion can be initiated using an enyne with an i

51 ing some epoxides that do not undergo simple ring-expansion carbonylation.

52 c catalyst to facilitate a novel cyclisation/ring expansion cascade sequence.

53 ple nitroarenes by photochemical dearomative ring expansion centred on the conversion of the nitro gr

54 method expands the toolbox of radical-based ring expansions, complementing classical approaches such

55 iates into pyrrolizidines through an unusual ring expansion/contraction mechanism, and catalyze the b

56 The observed ring expansion/contraction reactions are characteristic

57 ized rings can be prepared using cyclization/ring expansion (CRE) cascade reactions, without resortin

58 BX, the resulting products undergo divergent ring expansions depending on the mode of activation, pro

59 Competition between direct atom transfer and ring expansion followed by diolate cycloreversion is dem

60 es 1,3-dipolar cycloaddition, regioselective ring expansion, followed by the elimination of tosyl gro

61 n of the alkene and subsequent acid-promoted ring expansion for the pyrrolidine formation.

62 A Pd(II)/Bronsted acid catalyzed migratory ring expansion for the synthesis of indene derivatives p

63 , 1-adamantyl, or 3-homoadamantyl, or by the ring expansion-fragmentation of R'CH(2)OCCl, with R' = 1

64 ion pairs, produced by either the direct or ring expansion-fragmentations, were identical, solvent-

65 concept of thionium ion-initiated pinacolic ring expansion has been developed for accessing C4'-spir

66 is retained, but protodecyclometalation and ring-expansion have been sparingly observed.

67 his common approach the hydrated imidazoline ring expansion (HIRE) reaction.

68 The hydrated imidazoline ring expansion (HIRE-type) reaction was investigated for

69 This approach in the context of ring expansion holds promise for preparing lactones from

70 ite can control whether the enzyme catalyzes ring-expansion, hydroxylation, or both reactions.

71 referred over an allylic pathway wherein the ring expansion in a Pd-pi-allyl intermediate occurs subs

72 stereoelectronic restrictions on homoallylic ring expansion in alkyne reactions and to develop a new

73 arbolines undergo sodium periodate oxidative ring expansion in the presence of formaldehyde and other

74 owed by reports on the use of cyclic ketones ring expansion in total synthesis.

75 In contrast, ring expansion is observed to be the major reaction path

76 kyl donor-acceptor cyclopropanes can undergo ring expansion leading to aliphatic azetidines without r

77 Ring expansion metathesis polymerization (REMP) is a rob

78 oromethyl)phen-1-yl)borate) were used in the ring expansion metathesis polymerization (REMP) of cycli

79 ng to the short list of catalysts capable of ring expansion metathesis polymerization (REMP), complex

80 first catalyst to polymerize norbornene via ring expansion metathesis polymerization to yield highly

81 res along their backbone were prepared using ring expansion metathesis polymerization.

82 Ring-expansion metathesis polymerization (REMP) has show

83 Ring-expansion metathesis polymerization (REMP) mediated

84 s of 66, 56, and 28 angstrom and used in the ring-expansion metathesis polymerization (REMP) of cycli

85 lar architecture were developed by combining ring-expansion metathesis polymerization and click chemi

86 lic organic nanostructures were prepared via ring-expansion metathesis polymerization of a dendronize

87 to dispense a pure cyclic polymer after bulk ring-expansion metathesis polymerization of cyclopentene

88 Here, ring-expansion metathesis polymerization was used to syn

89 ocycles were prepared in one step by a novel ring-expansion method using olefin metathesis.

90 We have expanded the scope of this ring expansion methodology and investigated the effect s

91 ell phenylnitrene, which is known to undergo ring expansion much more readily than phenylcarbene.

92 cts result from a combination of cyclopropyl ring expansion (N-biphenylazetium ion) and ethylene elim

93 th anomerization and furanosyl --> pyranosyl ring expansion occurred.

94 The asymmetric gold(I)-catalyzed ring expansion of 1-allenylcyclopropanols is described.

95 Direct 2C-ring expansion of 1-indanones with ynones to 5H-benzo[7]

96 We observed ring expansion of 1-methylcyclobutylfluorocarbene at 8 k

97 b) to 1-aza-1,2,4,6-cycloheptatetraene (3b), ring expansion of 1c to 3c is computed to be quite endot

98 A novel ring expansion of 2-azabicyclo[4.1.0]heptanes, readily a

99 obenzoazepinediones 15a-15c via the proposed ring expansion of 3-vinyl-3-hydroxyisoindolinone interme

100 e synthetic pathways involves the one-carbon ring expansion of a cyclic allylic phosphonate to a subs

101 tom tunneling reaction involving spontaneous ring expansion of a fused-ring benzazirine into a seven-

102 synthesized through a novel route involving ring expansion of a perhydroindolone to afford the AC ri

103 ys a unique synthetic strategy featuring the ring expansion of a substituted cyclopentanone to a cycl

104 The catalyzed desymmetrizative ring expansion of alkenylcyclobutanols promoted by halof

105 A novel, dual-pathway ring expansion of alkynylcyclopropanols is described.

106 rmediate by hydropalladation of allenes, the ring expansion of allenylcyclobutanol substrates proceed

107 tereochemistry, diastereoselective oxidative ring expansion of an alpha-hydroxyfuran to access the py

108 of (+)-plectosphaeroic acid C was formed by ring expansion of an epidisulfide precursor.

109 rst examples where both cyclopropanation and ring expansion of arenes were rendered reversible.

110 e novo protein, but also of enzyme-catalyzed ring expansion of aromatic heterocycles via carbene tran

111 The synthesis relied on the B-ring expansion of available 6-keto estradiol derivatives

112 We previously reported a Rh-catalyzed ring expansion of aziridines and N-sulfonyl-1,2,3-triazo

113 We report enantioselective one-carbon ring expansion of aziridines to make azetidines as a new

114 Here, we report a [3 + 3] ring expansion of bicyclic aziridines and rhodium-bound

115 Base-catalyzed ring expansion of both (+/-)/(-)-epi-claulansine D and (

116 ree steps by the alkylidene carbene-mediated ring expansion of commercial cycloheptanones.

117 The scope and limitations of the ring expansion of cyclic 2-hydroxymethyl amines induced

118 port here a catalytic method for the modular ring expansion of cyclic aliphatic alcohols.

119 report an unprecedented visible-light-driven ring expansion of cyclic oximes through a photochemical

120 Wacker-type pathway (involving a semipinacol ring expansion of cyclobutanol followed by a reductive e

121 tenones were synthesized by the diazomethane ring expansion of cyclobutanones, produced by the photoc

122 The reaction represents a ring expansion of DBU.

123 This led to an efficient three-atom ring expansion of diarene-fused [1.4]oxazepines and [1.4

124 Herein, we report a Lewis acid-mediated ring expansion of donor-acceptor cyclopropanes (DACs) to

125 of substituted dihydrotropones by two-carbon ring expansion of enol ethers of cyclopentane-1,3-dion.

126 ich included cyclization, rearrangement, and ring expansion of hemiacetal, 15, is proposed.

127 sequence starts with an asymmetric migratory ring expansion of indoline, tetrahydroquinoline, or tetr

128 thoxybenzaldehyde demonstrate the reversible ring expansion of methoxyphenylcarbene (CH(3)O-C(6)H(4)-

129 ceeds through a Michael addition followed by ring expansion of methylenecyclopropanes and nucleophili

130 bene precursors for the selective one-carbon ring expansion of N-substituted pyrroles and indoles to

131 he rate constant for carbon tunneling in the ring expansion of noradamantylmethylcarbene (1d) to 2-me

132 in N, did not play a significant role in the ring expansion of penicillin G by resting cells or cell-

133 n C synthase (DAOCS) catalyses the oxidative ring expansion of penicillin N, the committed step in th

134 ate an intermediate that catalyzes oxidative ring expansion of penicillin substrates in cephalosporin

135 port here the Sn-catalyzed mild protocol for ring expansion of peroxyoxindoles to afford the series o

136 the most plausible mechanism of cyclization/ring expansion of proline with o-alkynylbenzaldehyde.

137 seven-membered rings is reported through the ring expansion of stable azapentalene derivatives upon r

138 Unlike the comparable ring expansion of the (1)A(2) state of phenylnitrene (1b

139 to investigate the potential surface for the ring expansion of the (1)A(2) state of phenylphosphinide

140 The teixobactin pharmacophore tolerates ring expansion of the 13-membered ring to 14-,15-, and 1

141 This involves ring expansion of the acenaphthylene precursor to genera

142 ydro-4H-1,2-oxazines via a Cloke-Wilson-type ring expansion of the aryl-substituted cyclopropane carb

143 analogue was found to undergo an unexpected ring expansion of the bryolactone core to generate the c

144 ermediate with "6-6-5" rings followed by the ring expansion of the C-ring concomitant with the format

145 ibutable to 4-homoadamantyne, resulting from ring expansion of the carbene, could be detected.

146 ction, the reactions involving oxidation and ring expansion of the corrole macrocycle are described c

147 ed by acidic alumina-mediated regioselective ring expansion of the cyclopropyl ketone.

148 the syn-Tp'Re(O)(diolate) complex, formed by ring expansion of the epoxide.

149 pathway, the alkylidene ligand is lost, via ring expansion of the metallacyclobutane intermediate, l

150 ter complexation with metal ions, leading to ring expansion of the metallo-macrocycle.

151 ens type rearrangement leading to an [n + 1] ring expansion of the tetrahydrofuran moiety, which resu

152 do-1-benzyl-beta-lactams, and TEMPO-mediated ring expansion of these compounds to the corresponding N

153 y to induce 1,2-metalate rearrangements, via ring expansion of vinylcyclopropyl boronate complexes ac

154 onal theory computations of the Cu-catalyzed ring expansion of vinyloxiranes is mediated by a tracele

155 his paper highlights various methods for the ring expansion of vinyloxiranes, -thiiranes, and -azirid

156 The regiochemistry of ring expansions of 2-substituted cyclic ketones using 1,

157 rbonyl compounds were synthesized by azirine ring expansions of alkyl 2-diazo-3-oxo-3-(2H-azirin-2-yl

158 ction surfaces leading to rearrangements and ring expansions of azapentalene cycloadducts of imidazol

159 es described include EtMgBr-promoted pinacol ring expansions of hydroxy mesylates 23 and 34, intramol

160 prepared under mild conditions by employing ring expansions of silylated methyleneaziridines.

161 he Schmidt reaction permits stereocontrol in ring expansions of symmetrical cyclohexanones.

162 eview highlights the state-of-the-art of the ring expansions of three- and four-membered cycles and i

163 mer: conformational restriction of the sugar ring, expansion of the pyrimidine pi-stacking surface an

164 Here, we present an approach for the ring-expansion of ketones, enabled by the rare electroph

165 alosporin C, whereas the W82A mutant reduced ring-expansion of penicillin G (an "unnatural" substrate

166 5L/M306I triple mutant selectively catalyzed ring-expansion of penicillin G and had improved kinetic

167 CS to residue 310 (Delta310 mutant) enhanced ring-expansion of penicillin G by approximately 2-fold.

168 catalyzes two oxidative reactions, oxidative ring-expansion of penicillin N to deacetoxycephalosporin

169 The crucial step in this transformation is a ring-expansion of the anionic intermediate by [1,3] sigm

170 rahydrofurobenzofuran systems via an in situ ring-expansion of the cyclopropane carbaldehydes followe

171 Attempts to perform this ring expansion on a monocyclic analogue have been also e

172 azide addition to the carbonyl, followed by ring expansion or rearrangement, respectively.

173 ces clavuligerus, which selectively catalyze ring-expansion or hydroxylation reactions, respectively.

174 catalysis and gold catalysis is applied to a ring expansion-oxidative arylation reaction.

175 The ring-expansion pathway is described by the rate equation

176 s the reaction mechanism of the zwitterionic ring expansion polymerization (ZREP) of monosubstituted

177 rboxyanhydrides (NNCA) using LiHMDS promoted ring-expansion polymerization (REP) in DMF.

178 A novel, one-pot ring-expansion procedure was developed using Me3S(O)I, N

179 The unprecedented 3 -> 4 ring expansion process is argued to be driven by an ambi

180 ey finding is that the five- to six-membered ring expansion process is not a viable reaction pathway

181 of external esters, which then underwent the ring-expansion process, and the incipient carbocation wa

182 ition metal complexes as a catalyst for this ring-expansion process.

183 e to stable structures, can compete with the ring-expansion process.

184 e-like centers that compete effectively with ring expansion processes of cyclopropylcarbenes.

185 H(5))C(triple bond)CTol] (12-E and 12-Z); no ring expansion product was observed.

186 ienone led to the formation of a 2-tropolone ring expansion product, consistent with a direct 1,2-alk

187 te is the ketenimine or a ketenimine-derived ring expansion product.

188 A ring-expansion product derived from the norcaranyl C-2 c

189 oducts, while the O-atom found in the cation ring-expansion products was predominantly obtained by re

190 l group to the adjacent carbon to afford the ring-expansion products.

191 in Wagner-Meerwein shifts was examined in a ring expansion protocol.

192 ynthesis are a silicate-directed elimination/ring expansion reaction and a highly diastereoselective

193 The ring expansion reaction led to a variety of functionaliz

194 pin-2-ones based on the nucleophile-mediated ring expansion reaction of 5-functionalized 4-mesyloxyme

195 of Pd(II)-Bronsted acid catalyzed migratory ring expansion reaction of an indenyl cyclobutanol to a

196 ytochrome P450 that catalyses the remarkable ring expansion reaction that is required to produce the

197 sis of 1 and 2 required the development of a ring expansion reaction to provide a 6-membered ring sui

198 ch also required the development of a unique ring expansion reaction to provide a six-membered ring s

199 to form the bicyclic intermediate 2c in the ring expansion reaction, is computed to be only slightly

200 xample of a phosphorus analog of the Buchner ring expansion reaction.

201 tically active 3-substituted piperidines via ring expansion reaction.

202 t, Delta310/M306I, selectively catalyzed the ring-expansion reaction and had similar kinetic paramete

203 Mechanistic studies provide evidence for the ring-expansion reaction being the result of a cascade ba

204 l provides an unusual opportunity to study a ring-expansion reaction controlled entirely by stereoele

205 A catalytic protio-semipinacol ring-expansion reaction has been developed for the highl

206 The technique described here involves a ring-expansion reaction of a 4-substituted cyclohexanone

207 It was also found that the ring-expansion reaction rate is more than 1 order of mag

208 The ring-expansion reaction takes place at 10 K with a rate

209 nine, but could be explained by a subsequent ring-expansion reaction to give an eight-membered ring v

210 protocol carries out the diastereoselective ring-expansion reaction with higher selectivity than com

211 This Michael-initiated ring-expansion reaction would enable two C-C and one C-O

212 into variants that can catalyze an oxidative ring-expansion reaction, showcasing the potential of uti

213 The lactones are prepared via cascade ring expansion reactions and elaborated via Suzuki-Miyau

214 These ring expansion reactions involve enamide (X-ray evidence

215 The ring expansion reactions of 1 with benzene and 1,4-bis(t

216 The origins of these differences between the ring expansion reactions of 1b and 1c have been elucidat

217 ns, we explore the mechanism of redox-active/ring expansion reactions of aldehydes furnishing lactone

218 Ring expansion reactions of strained vinylic heterocycli

219 es of arenes in thermally reversible Buchner ring expansion reactions, marking the first examples whe

220 s of oxetane derivatives in ring-opening and ring-expansion reactions are described.

221 ontrasts with the more usual silver-promoted ring-expansion reactions in which endocyclic bond cleava

222 ne) species by tetrabromodiborane(4)-induced ring-expansion reactions of cobaltocene.

223 n heterocycles can be prepared by performing ring-expansion reactions of gamma-silyloxy-gamma-lactams

224 hlorins is also susceptible to oxidation and ring-expansion reactions, generating chromene-annulated

225 Further, multiple transformations such as ring-expansion, reduction, aldol condensation, and Witti

226 e, a key cyclopentene annulation followed by ring-expansion results in an elusive hydrazulene that un

227 These include ring expansion, ring opening, and C-2 functionalization.

228 6',7',1'-lmnop]chrysene (14) by a double 5/6 ring-expansion/ring-contraction.

229 photoproduct proceeds more rapidly than the ring-expansion route.

230 xycyclization (spirocyclic selenolactams) or ring expansion (selenoquinolones) can be achieved throug

231 chanistic evidence for the 5-exo cyclization/ring expansion sequence.

232 be generated through a telescoped acylation/ring-expansion sequence, leading to the insertion of lin

233 ein, we demonstrate that a bromonium-induced ring expansion, starting from a common tetrahydrofuran-c

234 ng classical protecting groups, with the key ring expansion step initiated by nitro reduction and ami

235 Two new ring expansion strategies are reported for the synthesis

236 iketene annulation reaction and an oxidative ring expansion strategy designed to complement the presu

237 nes is reported, which provides a two-carbon ring expansion strategy for preparing seven-membered cyc

238 The previously reported ring-expansion strategy involving hydrolytically prone i

239 Herein, we describe a unique one-carbon ring-expansion strategy to access multi-substituted 2-in

240 own" from smaller rings using the successive ring-expansion (SuRE) method.

241 kers were made by regiochemically controlled ring expansion techniques (for substitution on Aca posit

242 Ring expansions that enable interconversion of privilege

243 esulted in the investigation of sulfur ylide ring expansions, thiocarbonyl chemistry, azomethine ylid

244 formation switch proceeds via strain-driven ring expansion through a 1,2-shift of the C-C bond.

245 nes, and their homologues) undergo migratory ring expansion through deprotonation of their benzylic u

246 ethoxycyclopropyl-d3-methylcarbene undergoes ring expansion to 1-d3-methylcyclobutene.

247 s, in which C-phenylnitrile imines 8 undergo ring expansion to 1-diazenyl-1,2,4,6-cycloheptatetraenes

248 ene has been found experimentally to undergo ring expansion to 2-chloroadamantene at cryogenic temper

249 arting from 1-isoquinolylcarbene; path a via ring expansion to 3-aza-benzo[c]cyclohepta-1,2,4,6-tetra

250 nother portion of 2-pyridylcarbene undergoes ring expansion to 4-azacyclohepta-1,2,4,6-tetraene 42, w

251 es in the transition-metal-free cyclobutanol ring expansion to 4-tetralones under N-bromosuccinimide

252 flates and subsequently treated with base, a ring expansion to 6,7,8,13-tetrahydro-5H-dibenzo[c,f]azo

253 id, which when heated in ethanol underwent a ring expansion to a hydroximino derivative, 38, of compo

254 cis to the ester group was found to undergo ring expansion to a mixture of cis- and trans-oxazolidin

255 c palladium intermediate, (3) regioselective ring expansion to a palladacycle, and (4) reductive elim

256 at the cyclopentadienyl ring and consecutive ring expansion to a pyridine ring.

257 e developed a rare example of regiodivergent ring expansion to access two regioisomers from a common

258 condensations, Diels-Alder chemistry, and a ring expansion to advance a chiral starting material con

259 owed by homoallyl (3-exo-trig/fragmentation) ring expansion to afford the benzylic radical necessary

260 cloheptatriene followed by isomerization and ring expansion to an aromatic 1,3,5-cyclooctatrien-7-yl

261 ction to aminofulvenediones like 38 and also ring expansion to azepinediones like 40 and cyclization

262 ycloaddition, a Claisen rearrangement, and a ring expansion to construct the core of the frondosin A

263 an efficient cyclopropanation and subsequent ring expansion to construct the cycloheptylfuranone core

264 Our synthesis features Carreira ring expansion to construct the tetracyclic spirooxindol

265 he known rearrangements to phenyldiazirines, ring expansion to diazenylcycloheptatetraene, or a new,

266 pene cyclase with a subsequent Ths-dependent ring expansion to form tetrahymanol.

267 ion to the aromatic ring occurs, followed by ring expansion to generate novel bicyclic sulfones.

268 the alkenyl cyclopropane 2 underwent smooth ring expansion to give the sesquiterpene (-)-delobabone

269 tep and (2) a regioselective Baeyer-Villiger ring expansion to install the fully substituted dihydroo

270 e 36, which undergoes tandem azide reduction/ring expansion to macrolactam 37.

271 carbene rearrangement, whereby DPC undergoes ring expansion to phenylcycloheptatetraene (PhCHT) follo

272 e, isamic acid 1, led to decarboxylation and ring expansion to quinazolino[4,5-b]quinazoline-6,8-dion

273 C-H activation with concomitant semipinacol ring expansion to the nascent pi-allylpalladium species.

274 nt dioxygenase which catalyzes the oxidative ring expansion to the tropolone nucleus via hydroxylatio

275 thylene aziridines results in a formal [3+1] ring expansion to yield highly substituted methylene aze

276 uivalents of alkynes by coupling homoallylic ring expansion to yield the formal "6-endo" products wit

277 e moiety were able to undergo regioselective ring expansions to produce corresponding cyclopentanones

278 cores, the enantioselective version of such ring-expansions to create (hetero)biaryl atropisomers ha

279 An unprecedented further oxidative ring expansion toward dibenzo[b,e]oxepines is also repor

280 t effect, and reaction mechanisms behind the ring expansion transformations, are presented.

281 nstead, 1 exhibits an intermolecular Buchner-ring-expansion-type reactivity; the silylene is capable

282 stitution with azide and imparted subsequent ring-expansion under metal/acid free-conditions.

283 lines following in situ Heine-type aziridine ring expansion upon treatment with BF(3).OEt(2).

284 These compounds undergo facial oxy-Cope ring expansions upon treatment with vinyllithium; the fo

285 ivity was also observed in the carbonylative ring expansion using Co(2)(CO)(8) to give a beta-lactam.

286 ewis acid-promoted Boyer-Schmidt-Aube lactam ring expansions using an azidoalkylboronate enabled gene

287 ewis acid-promoted Boyer-Schmidt-Aube lactam ring expansions using an azidoalkylboronate enabled gene

288 PhI(OAc)(2)-mediated ring expansion via 1,2-bond migration and concurrent sol

289 ed ring system, and (c) a diastereoselective ring expansion via a bicyclic aziridinium intermediate t

290 e five-membered ring in advance of transient ring expansion via diketone formation and intramolecular

291 the Pd-carbenoid complex, and intramolecular ring expansion via N-N bond cleavage.

292 eries of atom-swapping reactions followed by ring expansion via the oxaborin intermediate.

293 of bishomoallylic amines followed by in situ ring-expansion (via intramolecular ring-opening of the c

294 ditions were used with 14 other penicillins, ring expansion was achieved in all cases.

295 iazo strategy for the intramolecular azirine ring expansion was developed.

296 nusual stereospecific and diastereoselective ring expansion was uncovered.

297 tablish the structural requirements for this ring expansion, we have studied the effect of different

298 d the regioselective Tiffeneau-Demjanov-type ring expansion were the pivotal steps in these syntheses

299 bined with a subsequent cobalt(II)-catalyzed ring expansion with 1,3-diketones.

300 eterocycles, cyclopropanation and subsequent ring expansions, ylide formation with subsequent rearran