ライフサイエンスコーパス: ring flip

1 imidazole rings, such as the reaction-driven ring flip.

2 ng the chromophore proposed the prototypic D-ring flip.

3 barrier to N-inversion and a low barrier to ring-flip.

4 ectral congestion and line-broadening due to ring flips.

5 n breathing motions that are associated with ring flipping.

6 ernative conformations that are related by a ring flip and a small translation of the fluorinated ben

7 an electrocyclic ring opening followed by a ring flip and a subsequent electrocyclization proposed b

8 hin the stress-strain diagram, the thiophene ring flip and DAD planarization are thus two separated p

9 tation of such piperidines is the piperidine ring flip and not nitrogen inversion or rotation about t

10 Correlation between pyranose ring flipping and the conformation of the 1,4-glycosidic

11 arable to the enthalpic barriers typical for ring flips and disulfide isomerizations at ambient tempe

12 sult was a relatively high-energy barrier to ring-flip and a low barrier to N-inversion.

13 were the Gibbs free energy barriers for the ring-flip and the N-inversion.

14 The conformational inversion (ring-flip) and nitrogen-atom inversion (N-inversion) ene

15 elical foldamers is coupled with cyclohexane ring-flipping, and results in a reversal of the directio

16 er redistribution in the form of a thiophene ring flip as the major part of the overall mechanochromi

17 opose a proton conduction mechanism in which ring-flip-assisted imidazole deprotonation is the rate-l

18 bound pentafluorobenzyl ring undergoes rapid ring-flipping at about 20 000 s(-1).

19 The ring flip barrier of a series of benzannulated cycloocta

20 The His-175 imidazole ring flips becoming almost perpendicular to the original

21 , benditerpenoic acid exists in two distinct ring-flipped bicyclic conformations with a rotational ba

22 ed bicyclic nitriles, whereas generating the ring-flipped conformer, through a stepwise sequence, all

23 however, due to its clear preference for the ring-flipped coplanar conformation.

24 the lowest-energy stereodynamic process was ring-flip coupled with N-inversion, as N-inversion alone

25 ray data, this suggests that the chromophore ring flips during the transition from pB' to pB.

26 ively trapped inside a MOF and find a phenyl ring flipping energy barrier of 43(6) kJ/mol.

27 ment would be necessary to accommodate these ring flipping events(1).

28 to (i) harvest potential benefits of stalled ring-flipping for refining NMR solution structures, (ii)

29 conversion process takes place by rotational ring flipping, has an activation energy of 22 kcal mol(-

30 ural changes are completed (phenylalanine F4 ring flips), highly collective and activated motions con

31 activity lend support to the reaction-driven ring flip hypothesis.

32 mization of the torsional barrier for phenyl ring flipping in a metal-organic framework (MOF) based o

33 BPTI and activation parameters available for ring-flipping in Iso-2-cytochrome c reveal that in these

34 erved site of Trp83 indicate that the indole ring flip is common in flaviviral NS2B-NS3 proteases in

35 yond detection and averaging of NOEs through ring-flipping is abolished.

36 a by delineating a specific sequence, Phe272 ring flip, large thumb movement, Arg258 rotation with re

37 that it enables a reaction-driven imidazole ring flip mechanism, overcoming a major dilemma inherent

38 hose co-planar A-C pyrrole rings support a D-ring flip mechanism.

39 proceed toward the product state without a "ring-flip mechanism", proposed earlier on the basis of N

40 internal motional modes associated with the ring flip of Phe 45 is hardly affected by lowering T wel

41 The ring flip of tetraphenylene proceeds through a nonplanar

42 ween the calculation and the dynamics of the ring flip of the unsymmetrical t-CHP ring and the observ

43 the structural rearrangements that accompany ring flipping of a buried tyrosine residue in an SH3 dom

44 ht bfloGFPa1, a Tyrosine (Tyr159) promotes a ring flipping of a Tryptophan (Trp157) that in turn allo

45 of about 4 s(-1), indicating that mobility (ring flipping) of the benzyl alcohol is relatively restr

46 imulations further suggest more frequent F87 ring flipping on the nanosecond time scale in the A25T d

47 Phe, it is shown that Phe56 undergoes a slow ring flipping on the NMR time scale in the triple mutant

48 2) and R(61,3) adducts, which underwent slow ring flips on the NMR time scale and for which small seq

49 as 27 pN at early stages of deformation, the ring flip precedes mechanically induced planarization of

50 The styrene aromatic rings flipped rapidly on the NMR time scale; under these

51 The reduced ring-flipping rate constant of Phe 45 in supercooled wat

52 At T = -15 degrees C, the ring-flipping rate constants of Tyr 23, Tyr 35, and Phe

53 increased flexibility, as probed by aromatic ring flip rates and native state hydrogen exchange.

54 As the thiophene ring flip requires much smaller forces than planarizatio

55 o dissect the kinetics of the conformational ring-flip that precedes C-3 acyl participation and the p

56 showed that aromatic side chains can undergo ring flips-that is, 180 degrees rotations-despite their

57 Conformational exchange via ring flipping then allows the rotor and stator to twist

58 ined upon PSM, but pore closing now leads to ring-flipping to avert steric clash of amide methyl grou