ライフサイエンスコーパス: ring-forming

1 defines the sides of the bowl and the lower ring forming a closed assembly that forms the bottom of

2 in the S(1)' region, with the benzothiazole ring forming a hydrogen bond with His-57 and an aromatic

3 revealed that the subunits are arranged in a ring forming a putative central channel.

4 ylate, situated near the face of an aromatic ring, forming a bond to an arginine residue of a ligand.

5 re integral parts of the Torsin/cofactor AAA ring, forming a composite, membrane-spanning assembly.

6 It consists of two heptameric rings forming a homotetradecamer with an inner chamber t

7 lat-lying hexagon and three fused pentagonal rings, forming a cluster consisting of 15 individual wat

8 Ring-forming AAA(+) chaperones solubilize protein aggreg

9 Ring-forming AAA+ chaperones exert ATP-fueled substrate

10 The ring-forming AAA+ hexamer ClpC1 associates with the pept

11 Hsp104 is a ring-forming AAA+ machine that recognizes both aggregate

12 on the links between early forms of flexible ring-forming aggregates and their role in disease.

13 ly different conformations, with the "upper" ring forming an open assembly that defines the sides of

14 able) tendency to abstraction of 3H from one ring, forming an eta3-cyclohexenyl compound, and that wi

15 slightly twisted with the two (planar) outer rings forming an angle of 7 degrees.

16 Yeast Hsp104 is a ring-forming ATP-dependent protein disaggregase that, to

17 ClpB is a ring-forming, ATP-dependent protein disaggregase that co

18 SKD3, also known as CLPB, is a ring-forming, ATP-fueled protein disaggregase essential

19 The synthesis concludes with a ring-forming benzylic C-H oxidation to deliver oxepane 1

20 ciation of intermediates after each of seven ring-forming catalytic cycles, there is an overall direc

21 Bacteria and chloroplasts require the ring-forming cytoskeletal protein FtsZ for division.

22 y capped on one side with a bridging benzene ring, forming deep, chemically accessible cavities.

23 Large ring-forming dehydrogenation is initiated by anodic oxid

24 ymes that catalyze transformations (pyridone ring-forming desaturation, piperidine ring cleavage, and

25 The combination of multiple ring-forming elementary steps into a single cascade sequ

26 iscovery to an apparently common beta-lactam ring-forming enzyme, are now being revealed.

27 , but the isolated individual members of the ring-forming group bind to the motor nonspecifically.

28 A combined pRNA ring-forming group was very specific for motor binding,

29 e terminal COOH group onto the His imidazole ring, forming imidazoline radical intermediates.

30 cluding a highly Z-selective, eight-membered-ring-forming intramolecular Julia-Kocienski reaction, a

31 nt peptide stapling approach and heterocycle ring-forming macrocyclizations are included, along with

32 E-selective olefin formation in macrocyclic ring-forming metathesis.

33 Three ring-forming methods were explored and the controlled ox

34 y at the amino acid sequence but also at the ring-forming moiety.

35 The predicted ring-forming motif of SpoIIIAH and other evidence led to

36 rations, methanol can add to the cyclopropyl ring-forming N-3-methoxypropyl-N-biphenyl iminium ion.

37 roach comprises two transformations: a large-ring-forming, nucleophilic capture of a transient acylke

38 amework of condensed Au(2)P(6) and Au(4)P(6) rings forming parallel channels, which are filled by lea

39 This ring-forming process is successful with a variety of una

40 iflates also enter into the benzofuran-3-one ring-forming process under thermal cyclization condition

41 d to carefully designed substrates mostly in ring-forming processes(3,4).

42 Hsp104 is a ring-forming protein disaggregase that rescues stress-da

43 ons with the major outer-membrane-associated ring-forming protein, MxiD.

44 Heat shock protein (Hsp) 104 is a ring-forming, protein-remodeling machine that harnesses

45 transenvelope base containing at least three ring-forming proteins (MxiD, MxiJ, and MxiG in Shigella)

46 eins, SpoIIIAG, which has remote homology to ring-forming proteins found in type III secretion system

47 ng the bacterial inner membrane (IM) (24-mer ring-forming proteins PrgH and PrgK in the Salmonella en

48 on a foundation of three highly oligomerized ring-forming proteins that create a hollow scaffold span

49 The gating ring-forming RCK domain regulates channel gating in resp

50 A number of procedural variants of the key C-ring-forming reaction are illustrated in multiple exampl

51 l cyclizations, a recently developed type of ring-forming reaction for the expansion of polyaromatic

52 This powerful ring-forming reaction very quickly assembles complex tet

53 The key ring-forming reaction, in which a diazo ketone is conver

54 Herein, we describe two effective ring-forming reactions between acetyl ketene and electro

55 -driven approach to enable the prediction of ring-forming reactions, for which we have demonstrated i

56 features two regio- and stereoselective THF ring-forming reactions.

57 e cladiellins has been constructed via three ring-forming reactions: (i) an intramolecular reductive

58 y through the sequential use of two powerful ring-forming reactions: a modern metallacycle-mediated a

59 Many studies focus on the ring-forming regions of subunits Ku70 and Ku80.

60 thesis of oxazolines using resin capture and ring-forming release that eliminates traditional purific

61 However, by altering the ring forming residues and appending thiol and thioester

62 tituted along their long edges with aromatic rings forming rigid, cruciform molecules.

63 nBA side groups being sandwiched by aromatic rings forming ring-and-lock associations driven by pi-si

64 ln, and Ile located at the i+1 to i+3 of the ring-forming sequences share the same spatial orientatio

65 on-oxidation protocol in the key pyrrolidine ring forming step, an efficient total synthetic route to

66 o form a phenanthrene intermediate, the next ring-forming step is diverted from the conventional Mall

67 containing substrates that bypass a critical ring-forming step when Trx is the substrate.

68 a beta-carbon atom of the furan core upon a ring-forming step, thereby providing an alternative disc

69 tilizes a Friedel-Crafts reaction as its key ring-forming step, whereas the second route relies on an

70 tween a nitroolefin and a nitrile as its key ring-forming step.

71 The key ring forming steps are both based on biosynthetic consid

72 n transformations described herein may mimic ring-forming steps in the biosynthesis of trans-syn-tran

73 The utility of this N-heterocyclic ring-forming strategy as a synthetic tool that makes use

74 tical to determine whether SpoIIIAH adopts a ring-forming structural motif, and whether interaction o

75 However, the epsilon cyclase adds only one ring, forming the monocyclic delta-carotene (epsilon, ps

76 are densely aggregated in well-defined actin rings forming the sealing zone.

77 IAI triad at the top of the cleft, and the I rings forming the two sides.

78 The first ring-forming thioboration reaction of C-C pi bonds is re