ライフサイエンスコーパス: rodent

1 a proxy signal for BOLD in a freely behaving rodent.

2 ge and tedious experimentation-especially on rodents.

3 ecrease in synGAP in the PSDs of Syngap1(+/-)rodents.

4 emory and often studied as spatial memory in rodents.

5 ty of frequency preferences is not unique to rodents.

6 gic stimuli induced process extension, as in rodents.

7 ved from studies of chronic stress models in rodents.

8 ns and has been suggested to mediate itch in rodents.

9 g-induced, or spontaneous mutation models in rodents.

10 as come from studies of food palatability in rodents.

11 canines but is not naturally transmitted by rodents.

12 ave been shown to regulate EGP in humans and rodents.

13 ecision-making in the brains of primates and rodents.

14 t predatory threat in Sahara-Sahelian desert rodents.

15 ent findings in the primary visual cortex of rodents.

16 s antidiabetic and antiobesity properties in rodents.

17 k that is appropriate for both young and old rodents.

18 during the dark (active) phase in nocturnal rodents.

19 d by its exclusive application to adult male rodents.

20 asked if the S1 CST response is conserved in rodents.

21 itive method of assessing memory updating in rodents.

22 ohol drinking by women and experimentally in rodents.

23 escence imaging, in conscious, freely moving rodents.

24 toxic responses in the livers and kidneys of rodents.

25 f the central nervous system, as compared to rodents.

26 nic progenitor cells derived from humans and rodents.

27 o inhibitory at an early postnatal period in rodents.

28 antinociceptive agent similar to morphine in rodents.

29 ectivity to EP2, a short plasma half-life in rodents (1.7 h) and low aqueous solubility (27 muM), lim

30 In rodents, (18)F-LW223 displayed a specific uptake consist

31 main pathogenic entity in AD, as compared to rodent Abeta, the rat Amyloid Precursor Protein (App) ge

32 llele because human-Abeta is more toxic than rodent-Abeta and the pathogenic role of the p.R47H TREM2

33 t EGR3 expression was reduced only in female rodents after 20 days of forced abstinence.

34 of head movement, or head-fixation, of awake rodents allows for sophisticated investigation of neural

35 romising therapeutics have shown efficacy in rodent Alzheimer's disease models yet failed to benefit

36 ession studies have implicated BC200 and the rodent analog BC1 as negative regulators of translation

37 n vitro, GNF2133 is able to proliferate both rodent and human beta-cells.

38 focusing on the drug metformin, in parallel rodent and human studies of radiation injury.

39 not fully recapitulate increased EE seen in rodent and in vitro studies.

40 ssion of voltage-gated potassium channels in rodent and primate brains using qPCR, in situ hybridizat

41 produces long-lasting behavioral deficits in rodent and primate models; however, the mechanisms invol

42 establishing similarities and differences in rodent and primate neuroanatomy.

43 In preclinical rodent and rabbit models, we show that this system enabl

44 with reduced regularity of grid patterns in rodents and a grid-cell model based on the eigenvectors

45 s a key structure in affective processing in rodents and activation of its human homolog, the ventrom

46 l sharing in the tropics, particularly among rodents and bats, and within- and between-order sharing

47 the patterns of SCGN staining differ between rodents and human brains.

48 ite that uses conserved mechanisms to infect rodents and human hosts.

49 okinetic Algorithm Mapping GRI Efficacies in Rodents and Humans (PAMERAH) built upon our previous hum

50 Experimental sleep-wake disruption in rodents and humans causally modulates beta-amyloid (Abet

51 Experimental evidence in rodents and humans suggests that long-term memory consol

52 Our findings, both in rodents and humans, enable noninvasive mapping of critic

53 sed as a time cue for the circadian clock in rodents and humans.

54 our in several species, including zebrafish, rodents and humans.

55 ic regulation of body weight in postpubertal rodents and humans.

56 ronal structure have been implicated in both rodents and humans.

57 scillations in the peri-infarct zone in both rodents and humans.

58 en osteocalcin and IL-6 is conserved between rodents and humans.

59 igh-density cellular connectivity studies in rodents and imaging-based analyses of human brains.

60 effectively extinguished conditioned fear in rodents and lacked cardiac and behavioral side effects,

61 Research on rodents and non-human primates has established the invol

62 ed decisions, recent perturbation studies in rodents and non-human primates have challenged the hypot

63 In studies of both rodents and non-human primates, maternal obesity also pr

64 e for self and others stems from research in rodents and other non-human animals(1-3).

65 hich is tightly regulated developmentally in rodents and primates, and exhibits reduced cortical expr

66 Unlike rodents and primates, they demonstrate unique convergent

67 thin the primary somatosensory cortex of the rodent, and processes signals from the vibrissae.

68 ed to an adequate pharmacokinetic profile in rodents, and antinociceptive properties in the capsaicin

69 uman study participants, disease modeling in rodents, and cell-based assays, we examined whether S1P

70 cuitry underling complex movement control in rodents, and that striatal cholinergic interneurons are

71 oth chronic cuprizone and acute lysolecithin rodent animal models.

72 weaning and fasting-refeeding transitions in rodents are associated with changes in AMPK activation a

73 Rodents are critical for the transmission of Toxoplasma

74 Rodents are the most species-rich order within Mammalia

75 Post-inflammatory behaviours in rodents are widely used to model human depression and to

76 Using rodents as an example, we incorporate statistical differ

77 k analysis and identify NOX5, not present in rodents, as a sole neighbor to human vasodilatory endoth

78 In one habitat, a significant shift from rodent-associated to bird-associated Borrelia species wa

79 Medium-chain fatty acids (MCFAs) have in rodents been shown to have protective effects on glucose

80 atics and sequential organization of natural rodent behavior, its variation across individuals, and i

81 strated that interspecies complementation of rodent blastocysts lacking a developmental regulatory ge

82 n predator species richness and incidence of rodent-borne haemorrhagic fever with renal syndrome in t

83 Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks

84 ogical metric and data on human outbreaks of rodent-borne zoonoses, identifying matches between empir

85 tor) improves lung structure and function in rodent BPD models, severe side effects of VEGF therapy p

86 minergic neurons against toxic damage in the rodent brain and is in clinical trials to treat Parkinso

87 ivo optical imaging system across the entire rodent brain in under five minutes, making this methodol

88 action partners, ADAM22 and ADAM23, bound to rodent brain sections, and induced internalization of th

89 sition of signals in planar tissue including rodent brain slices, cultured cells, and brain regions w

90 Early models simply damaged the rodent brain through toxins or lesions.

91 ined receptor assembly in the monkey than in rodent brain.

92 eported the characterization of N-glycans in rodent brains, but there is a lack of spatial resolution

93 ances of N-glycans in the striatum and SN of rodent brains, serving as a foundation for identifying "

94 ve infiltration when transplanted into adult rodent brains.

95 D phenotype, higher psychosine levels in the rodent brainstem and spinal cord, and a significantly sh

96 Furthermore, propofol inhibits rodent but not human TRPA1.

97 g nonhuman primates, bats, horses, pigs, and rodents, but are not associated with disease.

98 Humans, nonhuman primates, and rodents can readily learn arbitrary categories defined b

99 Here we show that vascular injury in rodent carotid arteries induces YY1 expression along wit

100 We determined that, in the developing rodent cerebellar cortex (of both sexes), there is a tra

101 w developments in transgenic lines and human-rodent chimeras, we anticipate that in coming years, a c

102 However, recent evidence in human and rodent chronic sleep restriction (CSR) studies suggests

103 The standard partitioning of rodent cingulate cortex is inconsistent with that in any

104 tructural and functional organisation within rodent cingulate cortex itself.

105 y based on the nonhomologous partitioning of rodent cingulate cortex.

106 The emerging picture is one in which the rodent claustrum is closely tied to frontal/limbic regio

107 ave now assessed whether Muribacter muris (a rodent commensal from the same family) can prevent NTHi

108 he presence of chronically infected rodents, rodent control is unlikely to be a feasible approach for

109 d sediment analyses, we document hundreds of rodent coprolites found in association with plant materi

110 Dynamic clamp experiments in rodent cortical neurons confirm that channel cooperativi

111 we observed that human cMLCK phosphorylates rodent cTnI to a much smaller extent in vitro and in sit

112 tility of GenieScore for analyzing human and rodent data from proteomic and transcriptomic experiment

113 tions defined by state-specific markers from rodent data.

114 l rodent species Proechimys semispinosus The rodent deltavirus is highly distinct, showing a common a

115 cularized intron is reduced in the islets of rodent diabetes models and of type 2 diabetic patients,

116 Rodent dosimetry studies were performed to estimate the

117 d in sensory areas of head-fixed or tethered rodents due to technical limitations of recording from l

118 (VTA) contributes to reinforcement learning, rodent evidence suggests that slow changes in tonic VTA

119 Adolescent and adult rodents exposed to repeated administration of cannabinoi

120 ive therapies, based on systemic delivery in rodents failed, exposing the need for model with improve

121 Reliance on rodents for understanding pancreatic genetics, developme

122 f Peromyscus maniculatus (PEMA), an abundant rodent found across North America.

123 n intervention is applied to pregnant female rodents (genuine replicates) but the hypothesis is about

124 human spatial memory in a similar manner to rodent grid-cell activity and, therefore, strengthen the

125 now, the barrel cortex of common laboratory rodents has been an exceptionally useful model for study

126 Recent work in humans and rodents has demonstrated that the clinical utility of th

127 ctroretinography (ERG) studies in humans and rodents have revealed that retinal dysfunction is demons

128 Translational studies in rodents have used optogenetic and chemogenetic tools to

129 Two independent rodent heart failure models were used for the studies: t

130 ion as a prevention or treatment strategy in rodent heart failure models.

131 ene expression but phase-shifted relative to rodent hearts.

132 The recent discovery of an HCV-like rodent hepacivirus (RHV) enabled the development of such

133 Using rodent hepacivirus (RHV), a homolog of HCV that shares m

134 Early work in rodents highlighted the gut microbiota's importance in m

135 In the rodent hippocampus and entorhinal cortex, evidence accum

136 s GABAergic currents onto principal cells in rodent hippocampus likely through a postsynaptic mechani

137 sments in vivo after mAb injections into the rodent hippocampus.

138 eral posterior nucleus (LP) of thalamus, the rodent homologue of primate pulvinar, projects extensive

139 caution when translating data obtained from rodent HSC to events occurring in human cells.

140 ave lenses, saddle surfaces, waterdrops, and rodents, illustrate the essential ideas.

141 Initial rodent imaging studies showed that Gd(1) remains in the

142 ntial indicator of animal affect; humans and rodents in negative affective states often show potentia

143 Chronic stress in both humans and rodents induces a robust downregulation of neuroligin-2,

144 In adult rodents, inhibition of Cyp26a1 and Cyp26b1 increases atR

145 Adult neurogenesis in rodents is modulated by dopaminergic signaling and inhib

146 propose that Gestalt theory may explain why rodent islet architecture has historically been seen as

147 y linked to the long-standing dogma that the rodent islet has a mantle of non-beta-cells and that the

148 The unique architecture of rodent islets, a so-called core-mantle arrangement seen

149 uced by chronic ER stress in INS-1 cells and rodent islets.

150 gion that might correspond to a hypothetical rodent large delta antigen.

151 and hippocampal-dependent spatial memory in rodents, leading to clinical trials in human neurodegene

152 imorphic, and have been reproduced using the rodent limited bedding paradigm of early adversity.

153 the caregiver-infant context, we review the rodent literature on early-life fear development to char

154 Given the rodent literature, we hypothesised that minocycline woul

155 lation of B mAb-Ds was 57-83% but 15-58% for rodent mAb-Ds.

156 Disruption of PIMMS43 in the rodent malaria parasite Plasmodium berghei triggers robu

157 d female gametocytes and to ookinetes in the rodent malaria parasite Plasmodium berghei.

158 olves a longstanding debate by revealing how rodent mating plugs promote fertilization success under

159 principal neurons from slice preparations of rodent medial entorhinal cortex (MEC), but their functio

160 fferences and similarities between human and rodent microglia.

161 Here, we used a MIA rodent model in which polyinosinic: polycytidylic acid (

162 controversies around how representative the rodent model is of the human disease, and therefore sign

163 Using a naturalistic rodent model of ELS, the limited bedding paradigm (LB) b

164 performance and synaptodendritic health in a rodent model of HAND, which recapitulates the neuroinfla

165 In a high-fat, high-cholesterol diet-induced rodent model of NAFLD, we observed a progressive stepwis

166 tilized single prolonged stress, a validated rodent model of post-traumatic stress disorder, in combi

167 A rodent model of resilience and vulnerability to AN would

168 To advance a rodent model of the complex movement deficits of Parkins

169 entate gyrus (DG) in an electric stimulation rodent model which displays classical HS damage similar

170 However, in the mouse, a major preclinical rodent model, there is still no functional imaging evide

171 behavior, cognition, and brain activity in a rodent model.

172 he BLA, and facilitates fear extinction in a rodent model.

173 rate impairments in cued turning behavior in rodents modeling the cholinergic-dopaminergic losses obs

174 egulation that are difficult to obtain using rodent models alone.

175 icial effects on renin-angiotensin-dependent rodent models and human hypertension.

176 The intensity of cue-induced drug seeking in rodent models correlates with the induction of transient

177 n for this is that mechanistic studies using rodent models do not incorporate a critical facet of hum

178 ion of prion isolates with several recipient rodent models expressing small ruminants or heterologous

179 Clinical relevance of rodent models of 2,8-DHA crystal nephropathy induced by

180 astolic function in 2 hypertension-dependent rodent models of cardiac fibrosis.

181 inical nonhuman primate model of MS, and two rodent models of demyelinating disease, we investigated

182 to manifest kidney injury in several diverse rodent models of diabetes.

183 Common across multiple rodent models of early adversity is increased signaling

184 isystem nature of phenotypes in patients and rodent models of GALNT2-CDG suggest that there are multi

185 for the detection of demyelinated lesions in rodent models of MS.

186 In rodent models of NAFLD, treatment with a surrogate of TV

187 tion over time, using three well-established rodent models of optic nerve injury.

188 t for evaluating the outcome of experimental rodent models of respiratory diseases.

189 -inflammatory and neuroprotective actions in rodent models of status epilepticus.

190 uroprotectant strategies that have worked in rodent models of stroke have failed to provide protectio

191 In rodent models of type 2 diabetes (T2D), sustained remiss

192 In rodent models overexpressing the PMP22 (peripheral myeli

193 Studies in genetically modified rodent models suggest that activating G protein signalin

194 onse to psychological stressors, and work in rodent models suggests that PACAP manipulation exerts do

195 wever, there is a growing body of work using rodent models that inform on these potential toxicities.

196 efore suggest the horse as an alternative to rodent models to study mechanisms resulting in aneuploid

197 rol (2-AG), exert anxiolytic-like effects in rodent models via 2-AG-dependent activation of CB(1) can

198 Rodent models with spontaneous Kcnn2 mutations show abno

199 In rodent models, early-life adversity directly impacts hip

200 everal studies of TRE have been performed in rodent models, human studies are only now emerging.

201 Based on rodent models, researchers have theorized that the hippo

202 In rodent models, stress in the pre-pubertal period impairs

203 In rodent models, these fatty acids alleviate obesity-assoc

204 d largely abolishes the development of VC in rodent models, while not causing toxicity related to ser

205 nicotine, or alcohol seeking, as assessed in rodent models.

206 enetic mechanisms and research with relevant rodent models.

207 brain is more similar to that of human than rodent models.

208 ge to produce addiction-related behaviors in rodent models.

209 nduce the formation of high-grade gliomas in rodent models.

210 y defined in both the clinic and preclinical rodent models.

211 omparable with similar data from preclinical rodent models.

212 as an AI candidate gene through its study in rodent models.

213 r, replication was marginally reduced in two rodents models.

214 ifferences in timing and distribution across rodent, monkey and human studies.

215 Using simultaneous recordings of rodent motor (M1) and premotor (M2) cortex and computati

216 parative phylogenetic analyses on Australian rodents (Muridae: Hydromyini) and show that sociality ev

217 visual space, similar to those identified in rodents navigating physical space.

218 c potential using transfected HEK293T cells, rodent neuronal preparations, and behavioural and electr

219 release of misfolded alphaSN from human and rodent neurons is relevant to the progression and spread

220 growth and synaptic connectivity in cultured rodent neurons, but whether clinically relevant cytokine

221 In human and rodent neurons, CGG RAN-blocking ASOs suppressed repeat

222 While this gene is well studied in rodent neurons, its function in human neurons remains un

223 ive A1-like astrocytes is toxic to human and rodent neurons.

224 nd gene signatures associated with human and rodent nonalcoholic fatty liver disease (NAFLD) and hepa

225 CI in various animal models (lamprey, chick, rodents, nonhuman primates), different forms of spontane

226 In rodents, nucleus accumbens (NAc) afferents from the vent

227 rrhine (or New World) monkeys and caviomorph rodents of the Western Hemisphere derive from source gro

228 a two-choice interval-discrimination task in rodent OFC, specifically designed such that a lose-switc

229 In various altricial rodents, OHCs become functionally competent from around

230 Drosophila neurons, mouse muscle cells, and rodent oligodendrocytes.

231 This capromyine rodent once inhabited many islands but is now restricted

232 We demonstrate that the human and rodent ONLR possesses a mitotically active, age-depletab

233 Investigators acknowledge the limitations of rodent or non-human primate stroke models, hundreds of p

234 tral hippocampus and the prelimbic cortex in rodents or the dorsal anterior cingulate cortex in human

235 P2Y14 was expressed in both human and rodent pancreatic beta-cells.

236 ntal CM (ECM), induced by infection with the rodent parasite, Plasmodium berghei ANKA (PbANKA) has be

237 vivo infections of laboratory animals using rodent parasites.

238 nical studies show space radiation decreases rodent performance in low- and some high-level cognitive

239 Using a rodent periodontitis model, we assessed the ability of P

240 kinase in the dorsomedial striatum (DMS) of rodents plays a central role in mechanisms underlying ex

241 RI dynamics not captured by experiments on a rodent population (false negatives).

242 Certain arenaviruses that circulate in rodent populations can cause life-threatening hemorrhagi

243 In rodents, postnatal maturation of movement occurs from ro

244 le integration of head and visual signals in rodent primary visual cortex.

245 V) delivery of constitutively active Pfn1 to rodents promoted axonal regeneration, neuromuscular junc

246 the bulk and single-cell level in humans and rodents provide new insight into microglia-astrocyte com

247 Conversely, previous work in rodents provided conflicting results.

248 In the rodent, purinergic signaling is associated with changes

249 NA) modules showed significant enrichment of rodent quiescent stem cell marker genes (GSE70696_QNPbyT

250 thin the brains of large animals compared to rodents, rendering this approach suboptimal for treatmen

251 ssant effects of ketamine and (2R,6R)-HNK in rodents require activation of the mTORC1 kinase(10,11).

252 For NASA's Rodent Research-1 mission, female mice (ten 32 wk C57BL/

253 ailable - but currently not employed by most rodent researchers.

254 ysiological analysis of neuronal function in rodent retinal explants is useful for the study of early

255 Using patch-use theory, we evaluated the rodents' risk-assessment from each snake-separately, tog

256 Due to the presence of chronically infected rodents, rodent control is unlikely to be a feasible app

257 n the hippocampus encode information about a rodent's prior trajectory during performance of a contin

258 In a rodent schizophrenia model characterized by impaired glu

259 lly described in humans, identification of a rodent SN would provide the ability to mechanistically i

260 nfection are limited because most laboratory rodent species are refractory to disease.

261 cur in humans, identified in the neotropical rodent species Proechimys semispinosus The rodent deltav

262 Most accessible TEs are rodent-specific.

263 Local field potential recordings in rodent striatum show dopamine- and reward-dependent tran

264 s with meta-regression of 603 interventional rodent studies (10,364 animals) in NAFLD to assess which

265 however there is controversy from human and rodent studies as to whether ApoE4 is a risk factor for

266 Prior rodent studies have implicated these regions in regulati

267 Rodent studies indicate that ghrelin receptor blockade r

268 mologous definition better aligns results of rodent studies with those of other species, and reveals

269 Notably, this contrasts with rodent studies, where sex differences are focused in dee

270 hose of Nurr1/Nr4a2, have suggested that the rodent subplate and the persistent subplate cells in Lay

271 ntains a single active gene (AOX1), those of rodents, such as mice, are endowed with four genes (Aox1

272 In rodents, such drugs both diminish obesity and improve gl

273 ower in frequency and less prevalent than in rodents, suggesting interspecies differences in theta's

274 Extensive data from studies in rodents support a model in which theta oscillations fulf

275 ity from sensory discrimination to choice in rodent taste cortex.

276 Based on in vitro and rodent testing, a combination of two SUDV-specific mAbs,

277 However, in mice and other rodents, the IFIT1 orthologue has been lost, and the clo

278 In humans and rodents, the iron-regulatory hormone hepcidin is profoun

279 tor (mMOR)-1G is abundant and conserved from rodent to human.

280 ks in the brain neuronal network that allows rodents to explore the environment whisking with their m

281 avirus and preferentially infects neurons in rodents to induce an encephalomyelitis similar to the hu

282 viral vectors to generate somatic-transgenic rodents to monitor signalling pathways in diseased organ

283 olabeled tracers, and multiphoton imaging in rodents to show instead that cerebrospinal fluid surroun

284 iments, we exposed populations of two desert rodents to two different viper species, testing their ab

285 ng and space flight and given the ability of rodent touchscreen tasks to assess functional integrity

286 There has been some success treating RICD in rodents using human neural stem cell (hNSC) transplantat

287 ot play as big a role in directly modulating rodent V1 activity as previously thought.

288 se findings indicate that the latency of the rodent VEP is sensitive to changes mediated by the incre

289 t the opposite circadian cycles in nocturnal rodents versus diurnal humans(1,2) may contribute to thi

290 Fossorial rodents were also the only locomotor mode to consistentl

291 Unlike in rodents, where the grin1 knockout is embryonic lethal, g

292 e two extremes are represented in humans and rodents; whereas the human genome contains a single acti

293 e 20 mg/kg provoked "fast" theta sniffing in rodents which correlated with increased locomotor activi

294 Increasing evidence suggests rodents will work to reduce the distress of a conspecifi

295 Humans and rodents with Comparative Gene Identification-58 (CGI-58)

296 del of nicotine vapor self-administration in rodents with relevance to electronic cigarette use in hu

297 ats are highly vocal, eusocial, subterranean rodents with, counterintuitively, poor hearing.

298 reversed neuropathic pain in male and female rodents without altering normal pain response.

299 hanism for pediatric obesity consistent with rodent work showing that high saturated fat diets increa

300 Clinical and rodent work suggests that this postpartum drop in estrog