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1 ations of glutamate exhibited time-dependent run down.
2 +), accounting for the use dependence of the run down.
3 e signature of a mitotic clock that does not run down.
4 t-containing GABA(A)Rs by preventing current run-down.
5 zing nicotinic currents demonstrated delayed run-down.
6 hibition is a key determinant of the rate of run-down.
7  time-dependent right-shift in V0.5 values ("run-down"); (3) speeds macroscopic current activation ki
8 found that TRPV1 activity in excised patches ran down and that MgATP reactivated the channel.
9  hslo channels in that they show very little run-down and are not modulated by the addition of DTT.
10 ard this loss of sensitivity to stimulation (run-down) and it can be inferred that they interact with
11 ve potentials, increases the rate of channel run-down, and decreases the single-channel open probabil
12  DAT-null mice expressed DISC, but this DISC ran down at a significantly higher rate than littermate
13 cterized phenomenon of Ca2+-dependent NMDA-R run down because the effect of PDGF was blocked by the p
14                            The time at which run-down began ( approximately 5-30 min) was correlated
15 significantly reduced the time to glycolytic run-down by approximately 33 and 65%, respectively.
16 or 7 +/- 1.2 min before its deactivation, or running down, by approximately 60 %.
17         When GIRK1/4 channels are allowed to run down completely, they are not activated by addition
18 Synaptic NMDARs were also subject to current run-down during repeated low-frequency synaptic stimulat
19                  A second component did not 'run down' during dialysis and was resistant to nicardipi
20         Channel activity declined with time (run-down) following activation by beta-NAD+ in excised p
21 rgues that both traits evolved to facilitate running down game by persistence.
22 e and recombinant channels was precluded by 'run-down', i.e. channel activity could be elicited for o
23          In inside-out patches, SOC activity ran down immediately upon excision but was reactivated s
24 ibited by both Ba2+ and quinidine, underwent run-down in excised patches in the absence of ATP, and w
25 nce of sensory inputs they exhibit a gradual run-down in frequency before spontaneously terminating.
26 eprivation which was dependent on a complete run-down in glycolysis and a fall in cellular energy sta
27 ulatory proteins that cause Ca(2+)-dependent run-down in hippocampal neurones.
28                                       Little run-down in peak current amplitude was induced provided
29 ates during cell exit from the tailbud, then runs down in the anterior-ward cell flow in the PSM, the
30 fter patch excision, suggesting that channel run-down is due, in part, to membrane depletion of PIP2.
31                            The NMDAR current run-down may be mediated in part by a Ca(2+)-independent
32                           (1) Time-dependent run down of mK(ATP) activity was reversed by phosphatidy
33 easurements demonstrated that Ca(2+) induced run down of the glutamate response by downregulating cat
34                                              Run down of the glutamate response was also voltage depe
35 gic transmitters, ATP and adenosine, control run- down of swimming in the Xenopus embryo.
36  a general feedback mechanism that underlies run-down of all episodic motor patterns in vertebrates.
37                                         This run-down of AMPA receptor activity was proposed to occlu
38 ection of PKA inhibitory peptides leads to a run-down of AMPA receptor responses and prevents long-te
39 SD for at least four hours and prevented the run-down of amplitudes that is typically observed and wa
40                                    Following run-down of Ca2+ oscillations, depolarisation briefly re
41                                              Run-down of cellular polyphosphoinositides by concentrat
42 tory cytokine release thereby preventing the run-down of CSD amplitudes.
43                    During trains of stimuli, run-down of EPSPs was less extensive in inflamed tissue
44            PIP2 significantly attenuated the run-down of HERG channel activity that we normally obser
45 lylimidodiphosphate (AMP-PNP) to prevent the run-down of IK(IR))and the Mg2+ dependence of the ATP ef
46                                          The run-down of institutions, the new paradigm of recovery a
47            The model reproduced the temporal run-down of motor activity seen in the real embryo sugge
48 d, while CPA greatly speeded up, the rate of run-down of motor activity.
49 hypoxia on neuronal function is to produce a run-down of synaptic transmission, and more prolonged hy
50 recordings from Muller cells revealed that a run-down of the inwardly rectifying K+ current (IK(IR))
51 nd adenosine therefore seems to underlie the run-down of the motor pattern for swimming in Xenopus.
52 ineurin in the patch pipette accelerates the run-down of whole cell GluR6 responses in cells co-trans
53 e absence of pipette ATP, both GBa and Gquin ran down over 10 min.
54 but not KIR1.1 or KIR2.1 currents typically 'ran down' over 5 min to 60-80% of maximum amplitude.
55 tase inhibitors, we investigated whether the run-down phase was the result of dephosphorylation by an
56 od of run-up was followed by a use-dependent run-down phase.
57 s greatly from passive entrapment in webs to running down prey items on foot.
58                   Channel activity typically ran down quickly, however, and was not recovered in the
59 transients of longer duration but which then ran down quickly.
60 lease from intracellular calcium stores, and run down rapidly at resting membrane potentials when cal
61             We also hypothesize that channel run-down reflects accumulation of nAChRs in long-lived d
62 d cAMP (100 microM) restored the activity of run-down ROMK1 channels in inside-out patches in oocytes
63 is with a dynamin-inhibitory peptide reduced run-down, suggesting a role for clathrin-mediated endocy
64  in the amplitude of NMDAR currents (current run-down) that was use dependent and not readily reversi
65 sion, as opposed to TNTs, in which filaments run down the center.
66 open diameter of approximately 5.5 angstroms run down the membrane thickness.
67 of porphyrins in an elongated central cavity running down the center of the structure.
68 zinc-binding site lies within the vestibules running down the central axis of the receptor.
69 otherwise regular honeycomb pattern of holes running down the length of a fine silica glass fiber.
70 ide of the helix and contains a channel that runs down the helix axis.
71 avelength-scale morphological microstructure running down their length.
72 cised patches, the delayed rectifier current ran down, unmasking other K+ channels.
73                                              Run down was triggered, at least in part, by a rise in i
74            Although the rate of Ca2+ current run-down was not affected by 10-15 microM free Ca2+ in t
75                                         This run-down was prevented by okadaic acid, whereupon ICl,Ca
76                                              Run-down was reduced by increasing intracellular Ca(2+)
77 einyl leukotriene type I receptor activation run down when cells are pretreated with Li(+), an inhibi
78 olution but when ATP was omitted the current ran down with time.
79                         Kir6.1-SUR1 currents ran down within seconds of patch excision preventing ana
80                          TRPM2 currents also run down within minutes, but the molecular mechanism of